Page last updated: 2024-10-28

lidocaine and Erythermalgia

lidocaine has been researched along with Erythermalgia in 13 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Research Excerpts

ExcerptRelevanceReference
"Nociceptive thresholds and supra-threshold pain ratings as well as their reduction upon local injection with lidocaine were compared between healthy subjects and patients with erythromelalgia (EM)."9.24Pain thresholds, supra-threshold pain and lidocaine sensitivity in patients with erythromelalgia, including the I848Tmutation in Na ( Helås, T; Jönsson, B; Jørum, E; Kleggetveit, IP; Quiding, H; Sagafos, D; Salter, H; Schmelz, M; Segerdahl, M; Zhang, Z, 2017)
"Erythromelalgia is a rare, chronic, debilitating condition characterized by redness, warmth, and severe burning pain of the distal extremities."5.33Primary erythromelalgia in a child responding to intravenous lidocaine and oral mexiletine treatment. ( Guite, JW; Hehir, D; Milovcich, K; Nathan, A; Rose, JB, 2005)
"In a family exhibiting severe familial erythermalgia involving 5 members over 3 generations, we treated 4 patients aged 41, 39, 19 and 15 years."5.32[Treatment of familial erythermalgia with the association of lidocaine and mexiletine]. ( Dupre, D; Guillet, G; Kupfer, I; Legroux-Crespel, E; Misery, L; Sassolas, B, 2003)
"Nociceptive thresholds and supra-threshold pain ratings as well as their reduction upon local injection with lidocaine were compared between healthy subjects and patients with erythromelalgia (EM)."5.24Pain thresholds, supra-threshold pain and lidocaine sensitivity in patients with erythromelalgia, including the I848Tmutation in Na ( Helås, T; Jönsson, B; Jørum, E; Kleggetveit, IP; Quiding, H; Sagafos, D; Salter, H; Schmelz, M; Segerdahl, M; Zhang, Z, 2017)
"The treatment of primitive erythermalgia is based on sodium channel blockers such as mexiletine or lidocaine infusions, and on drugs effective on neuropathic pain, such as gabapentin or amitryptiline, in case of erythermalgia associated with small fiber neuropathy."1.72[Paroxysmal vascular acrosyndromes: Practical approach to diagnosis and management]. ( Senet, P, 2022)
"Conclusion: Erythermalgia may involve the face alone, and combinative approaches may be of choice for its treatment."1.51Erythermalgia Involving the Face Alone: Two Case Reports. ( Huang, YB; Liu, JH; Luo, DQ; Weng, ZS; Wu, HH; Zhao, YK, 2019)
"Erythromelalgia has not been well characterized in the pediatric population."1.38Pediatric erythromelalgia: a retrospective review of 32 cases evaluated at Mayo Clinic over a 37-year period. ( Cook-Norris, RH; Cruz-Inigo, AE; Davis, DM; Davis, MD; Sandroni, P; Tollefson, MM, 2012)
"Erythromelalgia is a rare disorder characterized by recurrent pain attacks, swelling and redness in the distal extremities."1.38Primary erythromelalgia in a 12-year-old boy: positive response to sodium channel blockers despite negative SCN9A mutations. ( Berner, R; Creutzfeldt, R; Hufnagel, M; Jakob, A; Staszewski, O; Winterpacht, A, 2012)
"Erythromelalgia is a rare, chronic, debilitating condition characterized by redness, warmth, and severe burning pain of the distal extremities."1.33Primary erythromelalgia in a child responding to intravenous lidocaine and oral mexiletine treatment. ( Guite, JW; Hehir, D; Milovcich, K; Nathan, A; Rose, JB, 2005)
"In a family exhibiting severe familial erythermalgia involving 5 members over 3 generations, we treated 4 patients aged 41, 39, 19 and 15 years."1.32[Treatment of familial erythermalgia with the association of lidocaine and mexiletine]. ( Dupre, D; Guillet, G; Kupfer, I; Legroux-Crespel, E; Misery, L; Sassolas, B, 2003)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (15.38)18.2507
2000's5 (38.46)29.6817
2010's5 (38.46)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Senet, P1
Helås, T1
Sagafos, D1
Kleggetveit, IP1
Quiding, H1
Jönsson, B1
Segerdahl, M1
Zhang, Z1
Salter, H1
Schmelz, M1
Jørum, E1
Liu, JH1
Weng, ZS1
Luo, DQ1
Zhao, YK1
Wu, HH1
Huang, YB1
Cook-Norris, RH1
Tollefson, MM1
Cruz-Inigo, AE1
Sandroni, P3
Davis, MD4
Davis, DM1
Jakob, A1
Creutzfeldt, R1
Staszewski, O1
Winterpacht, A1
Berner, R1
Hufnagel, M1
Elgueta, F1
de la Cuadra-Fontaine, JC1
Clede, L1
Fierro, C1
Valderrama, A1
Legroux-Crespel, E1
Sassolas, B1
Guillet, G1
Kupfer, I1
Dupre, D1
Misery, L1
Nathan, A1
Rose, JB1
Guite, JW1
Hehir, D1
Milovcich, K1
Sheets, PL1
Jackson, JO1
Waxman, SG1
Dib-Hajj, SD1
Cummins, TR1
Rauck, RL1
Naveira, F1
Speight, KL1
Smith, BP1
Kuhnert, SM1
Phillips, WJ1

Trials

1 trial available for lidocaine and Erythermalgia

ArticleYear
Pain thresholds, supra-threshold pain and lidocaine sensitivity in patients with erythromelalgia, including the I848Tmutation in Na
    European journal of pain (London, England), 2017, Volume: 21, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Dose-Response Relationship, Drug; Double-Blind M

2017

Other Studies

12 other studies available for lidocaine and Erythermalgia

ArticleYear
[Paroxysmal vascular acrosyndromes: Practical approach to diagnosis and management].
    La Revue de medecine interne, 2022, Volume: 43, Issue:10

    Topics: Antibodies, Antinuclear; Aspirin; Calcium Channel Blockers; Erythromelalgia; Gabapentin; Humans; Ilo

2022
Erythermalgia Involving the Face Alone: Two Case Reports.
    Journal of oral & facial pain and headache, 2019,Summer, Volume: 33, Issue:3

    Topics: Erythromelalgia; Female; Humans; Lidocaine; Male; Middle Aged; Pain; Skin

2019
Pediatric erythromelalgia: a retrospective review of 32 cases evaluated at Mayo Clinic over a 37-year period.
    Journal of the American Academy of Dermatology, 2012, Volume: 66, Issue:3

    Topics: Adolescent; Anesthetics, Local; Cellulitis; Child; Child, Preschool; Comorbidity; Disease Progressio

2012
Primary erythromelalgia in a 12-year-old boy: positive response to sodium channel blockers despite negative SCN9A mutations.
    Klinische Padiatrie, 2012, Volume: 224, Issue:5

    Topics: Administration, Oral; Amines; Analgesics; Child; Cyclohexanecarboxylic Acids; Diagnosis, Differentia

2012
Erythromelagia: a rare and hard-to-treat condition: a 9-year-old boy responsive to intravenous lidocaine and oral mexilitene.
    Pain medicine (Malden, Mass.), 2013, Volume: 14, Issue:2

    Topics: Administration, Intravenous; Administration, Oral; Child; Erythromelalgia; Humans; Lidocaine; Male;

2013
[Treatment of familial erythermalgia with the association of lidocaine and mexiletine].
    Annales de dermatologie et de venereologie, 2003, Volume: 130, Issue:4

    Topics: Administration, Oral; Adolescent; Adult; Anesthetics, Local; Dose-Response Relationship, Drug; Drug

2003
Primary erythromelalgia in a child responding to intravenous lidocaine and oral mexiletine treatment.
    Pediatrics, 2005, Volume: 115, Issue:4

    Topics: Administration, Oral; Analgesia, Epidural; Anesthetics, Local; Bupivacaine; Child; Erythromelalgia;

2005
Lidocaine patch for pain of erythromelalgia: follow-up of 34 patients.
    Archives of dermatology, 2005, Volume: 141, Issue:10

    Topics: Adolescent; Adult; Aged; Anesthetics, Local; Erythromelalgia; Female; Follow-Up Studies; Humans; Lid

2005
A Nav1.7 channel mutation associated with hereditary erythromelalgia contributes to neuronal hyperexcitability and displays reduced lidocaine sensitivity.
    The Journal of physiology, 2007, Jun-15, Volume: 581, Issue:Pt 3

    Topics: Action Potentials; Anesthetics, Local; Binding Sites; Cell Line; Computer Simulation; Dose-Response

2007
Refractory idiopathic erythromelalgia.
    Anesthesia and analgesia, 1996, Volume: 82, Issue:5

    Topics: Adolescent; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anes

1996
Lidocaine and mexiletine therapy for erythromelalgia.
    Archives of dermatology, 1999, Volume: 135, Issue:12

    Topics: Administration, Oral; Adult; Drug Therapy, Combination; Erythromelalgia; Follow-Up Studies; Humans;

1999
Lidocaine patch for pain of erythromelalgia.
    Archives of dermatology, 2002, Volume: 138, Issue:1

    Topics: Administration, Cutaneous; Adolescent; Delayed-Action Preparations; Erythromelalgia; Female; Follow-

2002