lidocaine has been researched along with Endophthalmitis in 6 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Endophthalmitis: Suppurative inflammation of the tissues of the internal structures of the eye frequently associated with an infection.
| Excerpt | Relevance | Reference |
|---|---|---|
| "1% methylparaben for anesthesia may reduce rates of endophthalmitis after intravitreal (IVT) injection." | 7.80 | Antibacterial properties of 2% lidocaine and reduced rate of endophthalmitis after intravitreal injection. ( Chomsky, A; Hubbard, GB; Kim, SJ; Sheng, J; Tustin, A, 2014) |
| "The purpose of this study was to determine the incidence of infectious endophthalmitis after intravitreal injection of antivascular endothelial growth factor medications using 2% topical lidocaine gel anesthesia." | 7.77 | Incidence of endophthalmitis after intravitreal injection of antivascular endothelial growth factor medications using topical lidocaine gel anesthesia. ( Anderson, NG; Inman, ZD, 2011) |
| "Application of povidone-iodine before lidocaine gel, compared to after, significantly decreased rate of IVI endophthalmitis, with no significant changes in visual and microbiological outcomes." | 4.31 | Lowering the Incidence of Endophthalmitis Following Intravitreal Anti-VEGF Injection: An Analysis of Aseptic Protocol Adjustment. ( Horesh, R; Jewart, B; Lee, D; Seebruck, C; Uner, OE, 2023) |
| "1% methylparaben for anesthesia may reduce rates of endophthalmitis after intravitreal (IVT) injection." | 3.80 | Antibacterial properties of 2% lidocaine and reduced rate of endophthalmitis after intravitreal injection. ( Chomsky, A; Hubbard, GB; Kim, SJ; Sheng, J; Tustin, A, 2014) |
| "The purpose of this study was to determine the incidence of infectious endophthalmitis after intravitreal injection of antivascular endothelial growth factor medications using 2% topical lidocaine gel anesthesia." | 3.77 | Incidence of endophthalmitis after intravitreal injection of antivascular endothelial growth factor medications using topical lidocaine gel anesthesia. ( Anderson, NG; Inman, ZD, 2011) |
| " Injection of subconjunctival cefuroxime can be very painful, especially after phacoemulsification under topical anesthesia." | 3.71 | Topical anesthesia for phacoemulsification and painless subconjunctival antibiotic injection. ( Dinakaran, S; Kayarkar, VV, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Uner, OE | 1 |
| Lee, D | 1 |
| Horesh, R | 1 |
| Jewart, B | 1 |
| Seebruck, C | 1 |
| Tustin, A | 1 |
| Kim, SJ | 1 |
| Chomsky, A | 1 |
| Hubbard, GB | 1 |
| Sheng, J | 1 |
| Awotesu, S | 1 |
| Eke, T | 1 |
| Inman, ZD | 1 |
| Anderson, NG | 1 |
| RODGER, FC | 1 |
| Kayarkar, VV | 1 |
| Dinakaran, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of Three Different Anesthetic Approaches for Intravitreal Injections: A Prospective Randomized Trial[NCT02263690] | Phase 4 | 92 participants (Actual) | Interventional | 2014-06-30 | Completed | ||
| Cefazolin-Lidocaine Solution for Reducing Pain Associated With Subconjunctival Antibiotic Prophylaxis in Vitreo-Retinal Surgery[NCT02324166] | Phase 4 | 54 participants (Anticipated) | Interventional | 2015-01-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 other studies available for lidocaine and Endophthalmitis
| Article | Year |
|---|---|
Lowering the Incidence of Endophthalmitis Following Intravitreal Anti-VEGF Injection: An Analysis of Aseptic Protocol Adjustment.
Topics: Endophthalmitis; Humans; Incidence; Intravitreal Injections; Lidocaine; Povidone-Iodine; Retrospecti | 2023 |
Antibacterial properties of 2% lidocaine and reduced rate of endophthalmitis after intravitreal injection.
Topics: Anesthetics, Local; Anti-Bacterial Agents; Bacteriological Techniques; Colony Count, Microbial; Endo | 2014 |
Preoperative lidocaine gel.
Topics: Administration, Topical; Anesthetics, Local; Anti-Infective Agents; Bacteria; Colony Count, Microbia | 2010 |
Incidence of endophthalmitis after intravitreal injection of antivascular endothelial growth factor medications using topical lidocaine gel anesthesia.
Topics: Anesthesia, Local; Anesthetics, Local; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; A | 2011 |
REPOSITORY CORTICOTHERAPY IN OPHTHALMIC THEORY AND PRACTICE.
Topics: Drug Therapy; Endophthalmitis; Eye Diseases; Humans; Injections; Keratitis; Lidocaine; Methylprednis | 1965 |
Topical anesthesia for phacoemulsification and painless subconjunctival antibiotic injection.
Topics: Aged; Anesthesia, Local; Anesthetics, Local; Antibiotic Prophylaxis; Cefuroxime; Cephalosporins; Con | 2001 |