Page last updated: 2024-10-28

lidocaine and Endometrial Diseases

lidocaine has been researched along with Endometrial Diseases in 6 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kaya, C1
Sener, EB1
Koksal, E1
Ustun, YB1
Celik, H1
Sahinoglu, AH1
Edelstam, G1
Sjösten, A1
Jablonowska, B1
Kjellberg, S1
Spira, J1
Dogan, E1
Celiloglu, M1
Sarihan, E1
Demir, A1
Soriano, D1
Ajaj, S1
Chuong, T1
Deval, B1
Fauconnier, A1
Daraï, E1
Hasson, HM1
Richards, MT1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Injection of 0.125% Marcaine During Mid-Urethral Sling Placement for Pain Relief: A Randomized Control Trial[NCT00746863]42 participants (Actual)Interventional2007-01-31Completed
Double Blind, Randomized, Prospective Trial of Impact of Pain Scores on Intrauterine Lidocaine vs Normal Saline Infusion Before IUD Placement.[NCT01311102]Phase 440 participants (Actual)Interventional2008-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Difference in Postoperative Pain Using a Visual Analog Scale at 2 Hours.

"At approximately two hours postoperatively patients completed a visual analog scale (VAS), which was a 10-cm numeric scale on which 0 represented no pain and 10 represented the worst pain ever." (NCT00746863)
Timeframe: 2 hours postoperative from mid-urethral sling placement

Interventioncm (Mean)
Intervention Group - Received Marcaine1.9
Control Group - No Marcaine2.6

Difference in Postoperative Pain Using a Visual Analog Scale at 24 Hours.

"At approximately twenty-four hours postoperatively patients completed a visual analog scale (VAS), which was a 10-cm numeric scale on which 0 represented no pain and 10 represented the worst pain ever." (NCT00746863)
Timeframe: 24 hours postoperative from mid-urethral sling placement

Interventioncm (Mean)
Intervention Group - Received Marcaine2.0
Control Group - No Marcaine2.3

Difference in Postoperative Pain Using a Visual Analog Scale at 6 Hours.

"At approximately six hours postoperatively patients completed a visual analog scale (VAS), which was a 10-cm numeric scale on which 0 represented no pain and 10 represented the worst pain ever." (NCT00746863)
Timeframe: 6 hours postoperative from mid-urethral sling placement

Interventioncm (Mean)
Intervention Group - Received Marcaine2.1
Control Group - No Marcaine2.3

Difference in Successful Voiding Trial Prior to Discharge Following Placement of Mid-urethral Sling Via the Suprapubic Approach.

Prior to discharge, patients underwent voiding trials. At our institution, in order to pass the voiding trial, they must void at least 200 cc spontaneously and have less than 100 cc as a post void residual two times in a row. (NCT00746863)
Timeframe: From after surgery to discharge from hospital.

Interventionparticipants w/sucessful voiding trial (Number)
Intervention Group - Received Marcaine4
Control Group - No Marcaine7

In-hospital Medication Amounts

Secondary outcome included differences in amount of pain medication used in the hospital. This was assessed by comparing the number of pills of oral narcotics the patient took while hospitalized. (NCT00746863)
Timeframe: From surgery until discharge, average

Interventionnumber of pills (Mean)
Intervention Group - Received Marcaine4
Control Group - No Marcaine6

Pain During IUD Placement

"IUD was inserted following the manufacturer's instructions, and a pain score was immediately obtained. Pain was scored on 0-9 scale; with 0 being no pain and 9 being worst pain in life." (NCT01311102)
Timeframe: Immediately after IUD placement

Interventionunits on a scale of 0-9 (Mean)
Lidocaine2.95
Normal Saline3.68

Pain During Tenaculum Placement

"Pain score on 0-9 scale for tenaculum placement (without anesthesia); with 0 being no pain and 9 being worst pain in life. Taken to adjust for different pain thresholds among subjects" (NCT01311102)
Timeframe: Immediately following tenaculum placement

Interventionunits on a scale of 0-9 (Mean)
Lidocaine2.20
Normal Saline2.70

Pain Measurement During Liquid Infusion/Sounding

"After liquid infused into three parts of the endometrial cavity: in the lower one third, the middle, and at the top of the cavity. Pain was scored on a 0-9 scale; with 0 being no pain and 9 being worst pain in life." (NCT01311102)
Timeframe: Recorded at the end of the infusion

Interventionunits on a scale of 0-9 (Mean)
Lidocaine2.50
Normal Saline3.39

Pain Scores During Overall IUD Placement

"Pain score on 0-9 scale obtained just before the patient left the examination room; with 0 being no pain and 9 being worst pain in life." (NCT01311102)
Timeframe: Before patient left the examination room at conclusion of procedure

Interventionunits on a scale of 0-9 (Mean)
Lidocaine2.12
Normal Saline1.73

Trials

4 trials available for lidocaine and Endometrial Diseases

ArticleYear
Comparison of placebo and intrauterine lidocaine with/or without rectal diclofenac sodium suppositories used in office endometrial biopsy.
    JPMA. The Journal of the Pakistan Medical Association, 2015, Volume: 65, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Biopsy;

2015
Pertubation with lidocaine--a non-hormonal, long-term treatment of dysmenorrhea due to endometriosis.
    Sexual & reproductive healthcare : official journal of the Swedish Association of Midwives, 2012, Volume: 3, Issue:2

    Topics: Adult; Anesthetics, Local; Dose-Response Relationship, Drug; Double-Blind Method; Dysmenorrhea; Endo

2012
Anesthetic effect of intrauterine lidocaine plus naproxen sodium in endometrial biopsy.
    Obstetrics and gynecology, 2004, Volume: 103, Issue:2

    Topics: Administration, Oral; Adult; Aged; Ambulatory Care; Anesthetics, Local; Biopsy, Needle; Double-Blind

2004
Anesthetic effect of intrauterine lidocaine plus naproxen sodium in endometrial biopsy.
    Obstetrics and gynecology, 2004, Volume: 103, Issue:2

    Topics: Administration, Oral; Adult; Aged; Ambulatory Care; Anesthetics, Local; Biopsy, Needle; Double-Blind

2004
Anesthetic effect of intrauterine lidocaine plus naproxen sodium in endometrial biopsy.
    Obstetrics and gynecology, 2004, Volume: 103, Issue:2

    Topics: Administration, Oral; Adult; Aged; Ambulatory Care; Anesthetics, Local; Biopsy, Needle; Double-Blind

2004
Anesthetic effect of intrauterine lidocaine plus naproxen sodium in endometrial biopsy.
    Obstetrics and gynecology, 2004, Volume: 103, Issue:2

    Topics: Administration, Oral; Adult; Aged; Ambulatory Care; Anesthetics, Local; Biopsy, Needle; Double-Blind

2004
Lidocaine spray and outpatient hysteroscopy: randomized placebo-controlled trial.
    Obstetrics and gynecology, 2000, Volume: 96, Issue:5 Pt 1

    Topics: Aerosols; Ambulatory Surgical Procedures; Anesthetics, Local; Female; Humans; Hysteroscopy; Lidocain

2000

Other Studies

2 other studies available for lidocaine and Endometrial Diseases

ArticleYear
Clinical applications of the wing sound device.
    Obstetrics and gynecology, 1974, Volume: 43, Issue:4

    Topics: Adult; Biopsy; Cervix Uteri; Endometrium; Female; Follow-Up Studies; Genital Diseases, Female; Gynec

1974
Uterine curettage as an office procedure.
    Canadian Medical Association journal, 1972, Jul-22, Volume: 107, Issue:2

    Topics: Ambulatory Care; Anesthesia, Local; Curettage; Economics, Medical; Female; Humans; Lidocaine; Method

1972