lidocaine and Emesis studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Research Excerpts

Excerpt	Relevance	Reference
"Lignocaine has been shown to reduce the incidence of pain on injection of propofol."	9.07	Propofol injection pain: comparing the addition of lignocaine or metoclopramide. ( Mecklem, DW, 1994)
"Epistaxis is a common problem that occurs in up to 60% of the general population, and is a common emergency department (ED) complaint."	5.43	Lidocaine Toxicity During Attempted Epistaxis Cautery. ( Nicholas, E; Thornton, MD, 2016)
"Idiopathic subjective tinnitus (IST) is one of the most obscure otological pathologies."	5.28	Treatment of tinnitus by intratympanic instillation of lignocaine (lidocaine) 2 per cent through ventilation tubes. ( David, YB; Fradis, M; Podoshin, L, 1992)
"Children (3-16 yr) undergoing elective strabismus surgery as inpatients were randomly allocated to four anaesthetic techniques: (A) thiopentone induction and isoflurane maintenance; (B) as (A) plus ondansetron 5 mg x m(-2) i."	5.08	Oculocardiac reflex and postoperative vomiting in paediatric strabismus surgery. A randomised controlled trial comparing four anaesthetic techniques. ( Fuchs-Buder, T; Rifat, K; Sansonetti, A; Tramèr, MR, 1998)
"Lignocaine has been shown to reduce the incidence of pain on injection of propofol."	5.07	Propofol injection pain: comparing the addition of lignocaine or metoclopramide. ( Mecklem, DW, 1994)
" Subjects were randomized to initial dosing to a T4 dermatome surgical anesthetic level with either 3% CP or 2% lidocaine with 1:200,000 epinephrine and sodium bicarbonate (LEB)."	3.30	Postcesarean Analgesia With Epidural Morphine After Epidural 2-Chloroprocaine: A Randomized Noninferiority Trial. ( Lee, LO; Lu, M; Ramirez-Chapman, AL; Suresh, MS; White, DL; Zhang, X, 2023)
"Pelvic pain was assessed, with a 100 mm visual analogue scale, at 1 hour, at hospital discharge, and time of first analgesia or any other time analgesia was demanded."	2.68	Local anaesthetic on Filshie clips for pain relief after tubal sterilisation: a randomised double-blind controlled trial. ( Breeson, AJ; Ezeh, UO; Lamb, MD; Martin, JL; Shoulder, VS; Vellacott, ID, 1995)
"Nausea and vomiting is also a problem."	2.68	Analgesia after otoplasty: regional nerve blockade vs local anaesthetic infiltration of the ear. ( Casey, W; Conway, F; Cregg, N, 1996)
"This study was designed to determine and compare the dose-response characteristics, speed of onset, and relative potency of single-dose epidural fentanyl (F) and sufentanil (S) for postoperative pain relief."	2.68	A randomized, double-blind, dose-response comparison of epidural fentanyl versus sufentanil analgesia after cesarean section. ( Grass, JA; Harris, AP; Michitsch, R; Sakima, NT; Schmidt, R; Zuckerman, RL, 1997)
"IV lidocaine has a multidimensional effect on the quality of recovery."	2.52	Efficacy of Intravenous Lidocaine for Postoperative Analgesia Following Laparoscopic Surgery: A Meta-Analysis. ( Brady, RR; Fearon, KC; Foo, I; Kennedy, ED; Paterson, HM; Speake, D; Ventham, NT, 2015)
"Additionally, the incidence of postoperative nausea and vomiting, administration of pain rescue medication, time to hospital discharge and to first bowel movement, as well as any postoperative complications were recorded."	1.48	Factors associated with intravenous lidocaine in pediatric patients undergoing laparoscopic appendectomy - a retrospective, single-centre experience. ( Both, CP; Bühler, PK; Piegeler, T; Schmitz, A; Thomas, J; Weiss, M, 2018)
"Epistaxis is a common problem that occurs in up to 60% of the general population, and is a common emergency department (ED) complaint."	1.43	Lidocaine Toxicity During Attempted Epistaxis Cautery. ( Nicholas, E; Thornton, MD, 2016)
"Idiopathic subjective tinnitus (IST) is one of the most obscure otological pathologies."	1.28	Treatment of tinnitus by intratympanic instillation of lignocaine (lidocaine) 2 per cent through ventilation tubes. ( David, YB; Fradis, M; Podoshin, L, 1992)
"SUN 1165 had no effect on clonic convulsions induced by pentetrazol and pictrotoxin in mice, while both mexiletine and lidocaine prolonged the duration of clonic convulsions."	1.27	General pharmacological studies on N-(2,6-dimethylphenyl)-8-pyrrolizidineacetamide hydrochloride hemihydrate. 1st communication: effect on the central nervous system. ( Hashimoto, Y; Hatta, M; Hattori, Y; Hirotsu, I; Ishihara, T; Kihara, T; Kitakaze, Y; Miyata, T; Nakamura, S; Takahama, K, 1988)

Research

Studies (39)

Authors

Clinical Trials (6)

Trial Overview

Trial Outcomes

Clinical Duration

Timeframe	Studies, this research(%)	All Research%
pre-1990	21 (53.85)	18.7374
1990's	11 (28.21)	18.2507
2000's	1 (2.56)	29.6817
2010's	5 (12.82)	24.3611
2020's	1 (2.56)	2.80

Authors	Studies
Lee, LO	1
Ramirez-Chapman, AL	1
White, DL	1
Zhang, X	1
Lu, M	1
Suresh, MS	1
Echevarría, GC	1
Altermatt, FR	1
Paredes, S	1
Puga, V	1
Auad, H	1
Veloso, AM	1
Elgueta, MF	1
Both, CP	1
Thomas, J	1
Bühler, PK	1
Schmitz, A	1
Weiss, M	1
Piegeler, T	1
Clivatti, J	1
Siddiqui, N	1
Goel, A	1
Shaw, M	1
Crisan, I	1
Carvalho, JC	1
Ventham, NT	1
Kennedy, ED	1
Brady, RR	1
Paterson, HM	1
Speake, D	1
Foo, I	1
Fearon, KC	1
Nicholas, E	1
Thornton, MD	1
GEJROT, T	1
Arai, M	1
Nakazawa, K	1
Takagi, A	1
Kishi, R	1
Osada, K	1
Ryu, S	1
Miyake, F	1
Ezeh, UO	1
Shoulder, VS	1
Martin, JL	1
Breeson, AJ	1
Lamb, MD	1
Vellacott, ID	1
Edwards, ND	1
Chan, ST	1
Tham, CS	1
Mecklem, DW	1
Cregg, N	1
Conway, F	1
Casey, W	1
Grass, JA	1
Sakima, NT	1
Schmidt, R	1
Michitsch, R	1
Zuckerman, RL	1
Harris, AP	1
Tramèr, MR	1
Sansonetti, A	1
Fuchs-Buder, T	1
Rifat, K	1
Añíbarro, B	1
Seoane, FJ	1
Baheti, DK	1
Muir, VM	1
Leonard, M	1
Haddaway, E	1
Galway, JE	1
Caves, PK	1
Dundee, JW	2
Roberts, RH	1
Tan, ST	1
Sinclair, SW	1
Podoshin, L	1
Fradis, M	1
David, YB	1
Ghaly, G	1
Christensen, S	1
Farrow-Gillespie, A	1
Lerman, J	1
Hirotsu, I	1
Kihara, T	1
Nakamura, S	1
Hattori, Y	1
Hatta, M	1
Kitakaze, Y	1
Takahama, K	1
Hashimoto, Y	1
Miyata, T	1
Ishihara, T	1
Warner, LO	1
Rogers, GL	1
Martino, JD	1
Bremer, DL	1
Beach, TP	1
Tree-Trakarn, T	1
Pirayavaraporn, S	1
Müller, H	1
Chung, EK	1
Moore, J	1
Murnaghan, GA	1
Lewis, MA	1
Karlsson, E	1
Collste, P	1
Rawlins, MD	1
Filias, N	1
Milne, MK	1
Lawson, JI	1
Farber, HI	1
Abrahamsson, H	1
Thorén, P	1
Fisher, A	1
Bryce-Smith, R	1
Smith, ER	1
Duce, BR	2
Burckhardt, D	1
Sefidpar, M	1
Boyes, RN	1
Adams, HJ	1
Lawso, HH	1

Trial	Phase	Enrollment	Study Type	Start Date	Status
Use of Intravenous Lidocaine in the Prevention of Postoperative Vomiting in Elective Tonsil Surgery, With or Without Adenoids[NCT01986309]	Phase 4	92 participants (Actual)	Interventional	2012-03-31	Completed
Intravenous Lignocaine as an Analgesic Adjunct in Adolescent Idiopathic Scoliosis Surgery (IGNITE-AIS Study)[NCT04931433]	Phase 4	102 participants (Anticipated)	Interventional	2020-12-24	Recruiting
Effect of Intravenous Infusion of Magnesium Sulfate Associated or Not to Lidocaine On the Neuromuscular Blockade Induced by Muscle Relaxant Cistracurium[NCT02483611]	Phase 4	48 participants (Actual)	Interventional	2015-07-31	Completed
Therapeutic Efficacy of Intravenous Lidocaine Infusion Compared With Epidural Analgesia for Postoperative Pain Control in Adult Patients Undergoing Major Abdominal Surgery: Non-Inferiority Clinical Trial[NCT04017013]	Phase 4	210 participants (Actual)	Interventional	2020-03-01	Completed
High Dose Intravenous Lidocaine vs Hydromorphone for Acute Abdominal Pain in the Emergency Department: A Randomized, Comparative Efficacy Trial[NCT04398316]	Phase 4	187 participants (Anticipated)	Interventional	2021-02-18	Recruiting
Does Neurostimulation Improve Efficacy for Ultrasound-Guided Transperineal Pudendal Nerve Block In Children: A Randomized Clinical Trial[NCT03931850]		40 participants (Anticipated)	Interventional	2019-04-30	Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

"The clinical duration is the elapsed time for T1 recovery = 25% (Dur25%) of the original value of T1 after the infusion of cisatracurium.~This outcome meansure was presented in minutes." (NCT02483611)
Timeframe: Participants were followed during the anesthetic - surgical procedure, an average of 90 minutes

Final Recovery Index

Intervention	minutes (Median)
Group M	82.68
Group ML	86.33
Group C	64.8

"The final recovery index is the elapsed time between the T1 recovery = 25% (Dur25%) and T4 / T1 = 80% (TOF = 80%) after the infusion of cisatracurium.~This outcome measure was presented in minutes." (NCT02483611)
Timeframe: Participants were followed during the anesthetic - surgical procedure, an average of 90 minutes

HR - M1 (Heart Rate in the Moment 1)

Intervention	minutes (Mean)
Group M	27.97
Group ML	33.81
Group C	21.51

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The measure of heart rate was recorded and annotated at various times such as in the arrival of the patient in the operating room. This time point was named as moment '1'. (NCT02483611)
Timeframe: This measure of heart rate was performed when the patient arrived in the operating room

HR - M2 (Heart Rate in the Moment 2)

Intervention	beats/min (Mean)
Group M	79.94
Group ML	77.25
Group C	73.66

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as in the moment immediately before the anesthesia induction. This time point was named as moment '2'. (NCT02483611)
Timeframe: This measure of heart rate was performed immediately before induction of anesthesia

HR - M3 (Heart Rate in the Moment 3)

Intervention	beats/min (Mean)
Group M	74.69
Group ML	73.69
Group C	75.40

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as immediately before the start of the infusion of the solution X (magnesium sulfate or isotonic solution) and Y solution (lidocaine or isotonic solution). This time point was named as moment '3'. (NCT02483611)
Timeframe: This measure of heart rate was performed immediately before the start of the infusion of the solution X (magnesium sulfate or isotonic solution) and Y solution (lidocaine or isotonic solution)

HR - M4 (Heart Rate in the Moment 4)

Intervention	beats/min (Mean)
Group M	72.94
Group ML	74.19
Group C	75.40

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as in the end of the study solutions infusion. This time point was named as moment '4'. (NCT02483611)
Timeframe: This measure of heart rate was performed five minutes after M3 (in the end of the X and Y solutions infusion)

HR - M5 (Heart Rate in the Moment 5)

Intervention	beats/min (Mean)
Group M	71.94
Group ML	72.25
Group C	65.07

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as immediately before the tracheal intubation. This time point was named as moment '5'. (NCT02483611)
Timeframe: This measure of heart rate was performed immediately before the tracheal intubation

HR - M6 (Heart Rate in the Moment 6)

Intervention	beats/min (Mean)
Group M	67.56
Group ML	69.31
Group C	64.27

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as one minute after the tracheal intubation. This time point was named as moment '6'. (NCT02483611)
Timeframe: This measure of heart rate was performed one minute after the tracheal intubation

HR - M7a (Heart Rate in the Moment 7a)

Intervention	beats/min (Mean)
Group M	66.50
Group ML	68.19
Group C	65.13

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as 15 minutes after the traqueal intubation.This time point was named as moment '7a'. (NCT02483611)
Timeframe: This measure of heart rate was performed 15 minutes after the traqueal intubation

HR - M7b (Heart Rate in the Moment 7b)

Intervention	beats/min (Mean)
Group M	68.94
Group ML	68.19
Group C	67.13

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as 30 minutes after the traqueal intubation. This time point was named as moment '7b'. (NCT02483611)
Timeframe: This measure of heart rate was performed 30 minutes after the traqueal intubation

HR - M7c (Heart Rate in the Moment 7c)

Intervention	beats/min (Mean)
Group M	67.44
Group ML	68.38
Group C	64.00

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as 45 minutes after the traqueal intubation. This time point was named as moment '7c'. (NCT02483611)
Timeframe: This measure of heart rate was performed 45 minutes after the traqueal intubation

HR - M7d (Heart Rate in the Moment 7d)

Intervention	beats/min (Mean)
Group M	65.75
Group ML	65.75
Group C	62.33

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as 60 minutes after the traqueal intubation. This time point was named as moment '7d'. (NCT02483611)
Timeframe: This measure of heart rate was performed 60 minutes after the traqueal intubation

HR - M7e (Heart Rate in the Moment 7e)

Intervention	beats/min (Mean)
Group M	66.19
Group ML	65.31
Group C	61.93

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as 75 minutes after the traqueal intubation. This time point was named as moment '7e'. (NCT02483611)
Timeframe: This measure of heart rate was performed 75 minutes after the traqueal intubation

HR - M7f (Heart Rate in the Moment 7f)

Intervention	beats/min (Median)
Group M	66.50
Group ML	63.00
Group C	58.00

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as 90 minutes after the traqueal intubation. This time point was named as moment '7f'. (NCT02483611)
Timeframe: This measure of heart rate was performed 90 minutes after the traqueal intubation

Latency

Intervention	beats/min (Median)
Group M	66.00
Group ML	61.00
Group C	61.00

"The latency is computed as the elapsed time to reduce the response of T1 to 5% of the initial contraction force after the infusion of cisatracurium.~This outcome meansure was presented in seconds." (NCT02483611)
Timeframe: Participants were followed during the anesthetic - surgical procedure, an average of 90 minutes

MAP - M1 (Mean Arterial Pressure in the Moment 1)

Intervention	seconds (Mean)
Group M	139.70
Group ML	151.30
Group C	147.80

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as in the arrival of the patient in the operating room. This time point was named as moment '1'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed when the patient arrived in the operating room

MAP - M2 (Mean Arterial Pressure in the Moment 2)

Intervention	mmHg (Mean)
Group M	94.63
Group ML	88.75
Group C	100.10

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as in the moment immediately before the anesthesia induction. This time point was named as moment '2'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed immediately before induction of anesthesia

MAP - M3 (Mean Arterial Pressure in the Moment 3)

Intervention	mmHg (Mean)
Group M	87.63
Group ML	84.69
Group C	92.47

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as immediately before the start of the infusion of the solution X (magnesium sulfate or isotonic solution) and Y solution (lidocaine or isotonic solution). This time point was named as moment '3'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed immediately before the start of the infusion of the solution X (magnesium sulfate or isotonic solution) and Y solution (lidocaine or isotonic solution)

MAP - M4 (Mean Arterial Pressure in the Moment 4)

Intervention	mmHg (Mean)
Group M	75.88
Group ML	73.88
Group C	76.73

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as in the end of the study solutions infusion.This time point was named as moment '4'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed five minutes after M3 (in the end of the X and Y solutions infusion)

MAP - M5 (Mean Arterial Pressure in the Moment 5)

Intervention	mmHg (Median)
Group M	69.00
Group ML	63.00
Group C	74.00

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as immediately before the tracheal intubation. This time point was named as moment '5'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed immediately before the tracheal intubation

MAP - M6 (Mean Arterial Pressure in the Moment 6)

Intervention	mmHg (Median)
Group M	62.50
Group ML	61.50
Group C	67.00

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as one minute after the tracheal intubation. This time point was named as moment '6'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed one minute after the tracheal intubation

MAP - M7a (Mean Arterial Pressure in the Moment 7a)

Intervention	mmHg (Median)
Group M	64.50
Group ML	64.00
Group C	69.00

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as 15 minutes after the traqueal intubation. This time point was named as moment '7a'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed 15 minutes after the traqueal intubation

MAP - M7b (Mean Arterial Pressure in the Moment 7b)

Intervention	mmHg (Median)
Group M	66.00
Group ML	61.50
Group C	69.00

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as 30 minutes after the traqueal intubation. This time point was named as moment '7b'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed 30 minutes after the traqueal intubation

MAP - M7c (Mean Arterial Pressure in the Moment 7c)

Intervention	mmHg (Median)
Group M	66.50
Group ML	63.50
Group C	68.00

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as 45 minutes after the traqueal intubation. This time point was named as moment '7c'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed 45 minutes after the traqueal intubation

MAP - M7d (Mean Arterial Pressure in the Moment 7d)

Intervention	mmHg (Mean)
Group M	69.25
Group ML	63.00
Group C	69.00

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as 60 minutes after the traqueal intubation. This time point was named as moment '7d'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed 60 minutes after the traqueal intubation

MAP - M7e (Mean Arterial Pressure in the Moment 7e)

Intervention	mmHg (Median)
Group M	68.00
Group ML	62.00
Group C	66.00

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as 75 minutes after the traqueal intubation. This time point was named as moment '7e'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed 75 minutes after the traqueal intubation

MAP - M7f (Mean Arterial Pressure in the Moment 7f)

Intervention	mmHg (Median)
Group M	68.00
Group ML	66.00
Group C	69.00

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as 90 minutes after the traqueal intubation. This time point was named as moment '7f'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed 90 minutes after the traqueal intubation

Recovery Index

Intervention	mmHg (Median)
Group M	64.00
Group ML	64.50
Group C	72.00

"The recovery index is the elapsed time between the T1 recovery =25% (Dur25%) and T1 =75% (Dur75%) after the infusion of cisatracurium.~This outcome meansure was presented in minutes." (NCT02483611)
Timeframe: Participants were followed during the anesthetic - surgical procedure, an average of 90 minutes

Spontaneous Recovery (T4/T1=90%)

Intervention	minutes (Mean)
Group M	20.08
Group ML	20.26
Group C	14.53

"Spontaneous recovery is the elapsed time for the recovery of the TOF (T4 / T1) response to 90% of the original after infusion of cisatracurium.~This outcome measure was presented in minutes." (NCT02483611)
Timeframe: The participants were followed during the anesthetic - surgical procedure

Total Duration (Dur95%)

Intervention	minutes (Mean)
Group M	120.20
Group ML	126.70
Group C	90.03

"The total duration is the elapsed time for T1 recovery of the response to reach 95% of the initial after the infusion of cisatracurium.~This outcome measure was presented in minutes." (NCT02483611)
Timeframe: Participants were followed during the anesthetic - surgical procedure, an average of 90 minutes

Article	Year
Efficacy of Intravenous Lidocaine for Postoperative Analgesia Following Laparoscopic Surgery: A Meta-Analysis. World journal of surgery, 2015, Volume: 39, Issue:9 Topics: Administration, Intravenous; Analgesia; Analgesics, Opioid; Anesthetics, Local; Eating; Humans; Lapa	2015
Efficacy of Intravenous Lidocaine for Postoperative Analgesia Following Laparoscopic Surgery: A Meta-Analysis. World journal of surgery, 2015, Volume: 39, Issue:9 Topics: Administration, Intravenous; Analgesia; Analgesics, Opioid; Anesthetics, Local; Eating; Humans; Lapa	2015
Efficacy of Intravenous Lidocaine for Postoperative Analgesia Following Laparoscopic Surgery: A Meta-Analysis. World journal of surgery, 2015, Volume: 39, Issue:9 Topics: Administration, Intravenous; Analgesia; Analgesics, Opioid; Anesthetics, Local; Eating; Humans; Lapa	2015
Efficacy of Intravenous Lidocaine for Postoperative Analgesia Following Laparoscopic Surgery: A Meta-Analysis. World journal of surgery, 2015, Volume: 39, Issue:9 Topics: Administration, Intravenous; Analgesia; Analgesics, Opioid; Anesthetics, Local; Eating; Humans; Lapa	2015
Efficacy of Intravenous Lidocaine for Postoperative Analgesia Following Laparoscopic Surgery: A Meta-Analysis. World journal of surgery, 2015, Volume: 39, Issue:9 Topics: Administration, Intravenous; Analgesia; Analgesics, Opioid; Anesthetics, Local; Eating; Humans; Lapa	2015
Efficacy of Intravenous Lidocaine for Postoperative Analgesia Following Laparoscopic Surgery: A Meta-Analysis. World journal of surgery, 2015, Volume: 39, Issue:9 Topics: Administration, Intravenous; Analgesia; Analgesics, Opioid; Anesthetics, Local; Eating; Humans; Lapa	2015
Efficacy of Intravenous Lidocaine for Postoperative Analgesia Following Laparoscopic Surgery: A Meta-Analysis. World journal of surgery, 2015, Volume: 39, Issue:9 Topics: Administration, Intravenous; Analgesia; Analgesics, Opioid; Anesthetics, Local; Eating; Humans; Lapa	2015
Efficacy of Intravenous Lidocaine for Postoperative Analgesia Following Laparoscopic Surgery: A Meta-Analysis. World journal of surgery, 2015, Volume: 39, Issue:9 Topics: Administration, Intravenous; Analgesia; Analgesics, Opioid; Anesthetics, Local; Eating; Humans; Lapa	2015
Efficacy of Intravenous Lidocaine for Postoperative Analgesia Following Laparoscopic Surgery: A Meta-Analysis. World journal of surgery, 2015, Volume: 39, Issue:9 Topics: Administration, Intravenous; Analgesia; Analgesics, Opioid; Anesthetics, Local; Eating; Humans; Lapa	2015
Digitalis intoxication. Postgraduate medical journal, 1972, Volume: 48, Issue:557 Topics: Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Digitalis Glycosides; Edetic Acid; Electric Count	1972

Article	Year
Postcesarean Analgesia With Epidural Morphine After Epidural 2-Chloroprocaine: A Randomized Noninferiority Trial. Anesthesia and analgesia, 2023, 01-01, Volume: 136, Issue:1 Topics: Analgesia, Epidural; Analgesics, Opioid; Double-Blind Method; Female; Humans; Lidocaine; Morphine; N	2023
Intra-operative lidocaine in the prevention of vomiting after elective tonsillectomy in children: A randomised controlled trial. European journal of anaesthesiology, 2018, Volume: 35, Issue:5 Topics: Anesthetics, Local; Antiemetics; Child; Child, Preschool; Double-Blind Method; Elective Surgical Pro	2018
Local anaesthetic on Filshie clips for pain relief after tubal sterilisation: a randomised double-blind controlled trial. Lancet (London, England), 1995, Jul-08, Volume: 346, Issue:8967 Topics: Adult; Cyclizine; Diclofenac; Double-Blind Method; Female; Gels; Humans; Laparoscopy; Lidocaine; Mef	1995
The effects of 2% lignocaine gel on incidence of retching with the use of the laryngeal mask airway. Anaesthesia, 1995, Volume: 50, Issue:3 Topics: Adolescent; Adult; Anesthesia, General; Female; Humans; Laryngeal Masks; Lidocaine; Lubrication; Mal	1995
Propofol injection pain: comparing the addition of lignocaine or metoclopramide. Anaesthesia and intensive care, 1994, Volume: 22, Issue:5 Topics: Adult; Anesthesia Recovery Period; Anesthesia, Intravenous; Blood Pressure; Extrapyramidal Tracts; F	1994
Analgesia after otoplasty: regional nerve blockade vs local anaesthetic infiltration of the ear. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1996, Volume: 43, Issue:2 Topics: Adolescent; Analgesia; Anesthetics, Local; Child; Child, Preschool; Ear, External; Female; Humans; L	1996
A randomized, double-blind, dose-response comparison of epidural fentanyl versus sufentanil analgesia after cesarean section. Anesthesia and analgesia, 1997, Volume: 85, Issue:2 Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Anesthesia, Epidural; Anesth	1997
Oculocardiac reflex and postoperative vomiting in paediatric strabismus surgery. A randomised controlled trial comparing four anaesthetic techniques. Acta anaesthesiologica Scandinavica, 1998, Volume: 42, Issue:1 Topics: Adolescent; Alfentanil; Analgesics, Opioid; Anesthesia, General; Anesthetics, Inhalation; Anesthetic	1998
Effect of intercostal nerve blockade during operation on lung function and the relief of pain following thoracotomy. British journal of anaesthesia, 1975, Volume: 47, Issue:6 Topics: Blood Pressure; Bupivacaine; Headache; Humans; Intercostal Nerves; Lidocaine; Nerve Block; Pain, Pos	1975
Lignocaine vs bupivacaine in prominent ear correction: a controlled trial. British journal of plastic surgery, 1992, Volume: 45, Issue:7 Topics: Acetaminophen; Adolescent; Adult; Anesthesia, General; Anesthesia, Local; Bupivacaine; Child; Child,	1992
Incidence of emesis and postanesthetic recovery after strabismus surgery in children: a comparison of droperidol and lidocaine. Anesthesiology, 1989, Volume: 70, Issue:2 Topics: Adolescent; Anesthesia Recovery Period; Antiemetics; Child; Child, Preschool; Clinical Trials as Top	1989
Intravenous lidocaine reduces the incidence of vomiting in children after surgery to correct strabismus. Anesthesiology, 1988, Volume: 68, Issue:4 Topics: Child; Child, Preschool; Clinical Trials as Topic; Humans; Infant; Injections, Intravenous; Lidocain	1988
Postoperative pain relief for circumcision in children: comparison among morphine, nerve block, and topical analgesia. Anesthesiology, 1985, Volume: 62, Issue:4 Topics: Adolescent; Anesthesia, General; Anesthesia, Local; Bupivacaine; Child; Child, Preschool; Circumcisi	1985
Spinal analgesic agents. A comparison of cinchocaine, lignocaine and prilocaine. Anaesthesia, 1971, Volume: 26, Issue:3 Topics: Anesthesia, Spinal; Dibucaine; Female; Headache; Humans; Hypotension; Lidocaine; Prilocaine; Time Fa	1971

Article	Year
Factors associated with intravenous lidocaine in pediatric patients undergoing laparoscopic appendectomy - a retrospective, single-centre experience. BMC anesthesiology, 2018, 07-18, Volume: 18, Issue:1 Topics: Administration, Intravenous; Anesthetics, Local; Appendectomy; Case-Control Studies; Child; Constipa	2018
Quality of labour neuraxial analgesia and maternal satisfaction at a tertiary care teaching hospital: a prospective observational study. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2013, Volume: 60, Issue:8 Topics: Adjuvants, Anesthesia; Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesia, Patient-Contro	2013
Lidocaine Toxicity During Attempted Epistaxis Cautery. The Journal of emergency medicine, 2016, Volume: 51, Issue:3 Topics: Anesthesia, Local; Anesthetics, Local; Bradycardia; Cautery; Epistaxis; Humans; Lidocaine; Male; Sei	2016
INTRAVENOUS XYLOCAINE IN THE TREATMENT OF ATTACKS OF MENI'ERE'S DISEASE. Acta oto-laryngologica. Supplementum, 1964, Volume: 188 Topics: Humans; Injections, Intravenous; Lidocaine; Meniere Disease; Motion Sickness; Nausea; Nystagmus, Pat	1964
Brugada syndrome-like ST-segment elevation increase exacerbated by vomiting. Circulation journal : official journal of the Japanese Circulation Society, 2004, Volume: 68, Issue:7 Topics: Acetylcholine; Anti-Arrhythmia Agents; Coronary Vessels; Electrocardiography; Humans; Infusions, Int	2004
Lignocaine gel and the laryngeal mask airway. Anaesthesia, 1995, Volume: 50, Issue:8 Topics: Humans; Laryngeal Masks; Lidocaine; Vomiting	1995
Adverse reaction to lidocaine. Allergy, 1998, Volume: 53, Issue:7 Topics: Adolescent; Akathisia, Drug-Induced; Anesthetics, Local; Dizziness; Double-Blind Method; Euphoria; F	1998
Epidural analgesia with left lateral tilt for Caesarean section. Anaesthesia, 1975, Volume: 30, Issue:3 Topics: Adult; Anesthesia, Epidural; Apgar Score; Back Pain; Blood Pressure; Body Weight; Cesarean Section;	1975
Morbidity following dental extraction. A comparative survey of local analgesia and general anaesthesia. Anaesthesia, 1976, Volume: 31, Issue:2 Topics: Adolescent; Adult; Age Factors; Aged; Anesthesia, Dental; Anesthesia, General; Anesthesia, Local; Ch	1976
Treatment of tinnitus by intratympanic instillation of lignocaine (lidocaine) 2 per cent through ventilation tubes. The Journal of laryngology and otology, 1992, Volume: 106, Issue:7 Topics: Adult; Aged; Female; Humans; Injections; Instillation, Drug; Lidocaine; Male; Middle Aged; Middle Ea	1992
Local anesthesia blocks the antiemetic action of P6 acupuncture. Clinical pharmacology and therapeutics, 1991, Volume: 50, Issue:1 Topics: Acupuncture Analgesia; Adult; Anesthesia, Local; Female; Humans; Lidocaine; Nalbuphine; Postoperativ	1991
General pharmacological studies on N-(2,6-dimethylphenyl)-8-pyrrolizidineacetamide hydrochloride hemihydrate. 1st communication: effect on the central nervous system. Arzneimittel-Forschung, 1988, Volume: 38, Issue:10 Topics: Administration, Oral; Animals; Anti-Arrhythmia Agents; Body Temperature; Catalepsy; Cats; Central Ne	1988
[A severe complication of stellatum blockade]. HNO, 1969, Volume: 17, Issue:10 Topics: Autonomic Nerve Block; Ganglionic Blockers; Humans; Lidocaine; Male; Middle Aged; Procaine; Seizures	1969
A clinical evaluation of the maternal effects of lumbar extradural analgesia for labour. Anaesthesia, 1974, Volume: 29, Issue:5 Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Bupivacaine; Cesarean Section; Epinephrine; Extractio	1974
Plasma levels of lidocaine during combined treatment with phenytoin and procainamide. European journal of clinical pharmacology, 1974, Oct-04, Volume: 7, Issue:6 Topics: Aged; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Blood Pressu	1974
[Some suggestions for the treatment of myocardial infarct in the pre-hospitalization phase]. Revue medicale de la Suisse romande, 1973, Volume: 93, Issue:12 Topics: Allied Health Personnel; Ambulances; Angina Pectoris; Arrhythmias, Cardiac; Atropine; Droperidol; He	1973
Epidural analgesia for Caesarean section. A review of 182 cases. British journal of anaesthesia, 1973, Volume: 45, Issue:12 Topics: Anesthesia, Epidural; Blood Pressure; Bupivacaine; Cesarean Section; Epinephrine; Ergonovine; Female	1973
Fever, vomiting, and liver dysfunction with procainamide therapy. Postgraduate medicine, 1974, Volume: 56, Issue:1 Topics: Ampicillin; Blood; Chemical and Drug Induced Liver Injury; Digitalis; Drug Hypersensitivity; Female;	1974
Reflex relaxation of the stomach elicited from receptors located in the heart. An analysis of the receptors and afferents involved. Acta physiologica Scandinavica, 1972, Volume: 84, Issue:2 Topics: Animals; Aorta; Blood Pressure; Cats; Electric Stimulation; Evoked Potentials; Heart Conduction Syst	1972
The acute antiarrhythmic and toxic effects in mice and dogs of 2-ethylamino-2',6-'acetoxylidine (L-86), a metabolite of lidocaine. The Journal of pharmacology and experimental therapeutics, 1971, Volume: 179, Issue:3 Topics: Acetanilides; Administration, Oral; Animals; Arrhythmias, Cardiac; Blood Pressure; Chloroform; Dogs;	1971
[Digitalis poisoning. Diagnosis and therapy]. Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1971, Dec-21, Volume: 60, Issue:51 Topics: Arrhythmias, Cardiac; Digitalis Glycosides; Humans; Lidocaine; Phenytoin; Poisoning; Potassium; Vomi	1971
Oral absorption and disposition kinetics of lidocaine hydrochloride in dogs. The Journal of pharmacology and experimental therapeutics, 1970, Volume: 174, Issue:1 Topics: Absorption; Administration, Oral; Animals; Computers; Dogs; Female; Injections, Intravenous; Kinetic	1970
Some aspects of gastroscopy and gastric biopsy. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1970, Nov-28, Volume: 44, Issue:47 Topics: Anesthesia; Apnea; Biopsy; Gastroscopy; Humans; Lidocaine; Methods; Stomach; Vomiting	1970

lidocaine and Emesis