lidocaine has been researched along with Dupuytren Contracture in 15 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Dupuytren Contracture: A fibromatosis of the palmar fascia characterized by thickening and contracture of the fibrous bands on the palmar surfaces of the hand and fingers. It arises most commonly in men between the ages of 30 and 50.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dupuytren contracture is a debilitating disease that characteristically presents as a firm nodularity on the palmar surface of the hand with coalescing cords of soft tissue on the webs and digits." | 5.37 | Management of Dupuytren contracture with ultrasound-guided lidocaine injection and needle aponeurotomy coupled with osteopathic manipulative treatment. ( Aufiero, D; Meng, M; Montenegro, R; Sampson, S; Schulte, A; Trainor, D, 2011) |
| "In outpatients undergoing surgery for Dupuytren's contracture, a midhumeral block was used with the musculocutaneous and radial nerves blocked by lidocaine and the median and ulnar nerves blocked with bupivacaine." | 5.08 | The use of a selective axillary nerve block for outpatient hand surgery. ( Benhamou, D; Bouaziz, H; Khoury, A; Mercier, FJ; Narchi, P; Poirier, T, 1998) |
| " We prospectively evaluated the use of four anesthetic techniques (general anesthesia, axillary block, and IV regional anesthesia [IVRA] with lidocaine with or without clonidine) for patients undergoing fasciectomy for Dupuytren's contracture." | 3.73 | The incidence of complex regional pain syndrome after fasciectomy for Dupuytren's contracture: a prospective observational study of four anesthetic techniques. ( Dixon, D; Faruqi, S; Madabhushi, L; Pristas, R; Reuben, SS; Wenner, S, 2006) |
| " Subsequently 80 patients were treated in a random, placebo-controlled, dose-response study of collagenase at 2 test centers." | 2.70 | Collagen as a clinical target: nonoperative treatment of Dupuytren's disease. ( Badalamente, MA; Hentz, VR; Hurst, LC, 2002) |
| "Dupuytren contracture is a debilitating disease that characteristically presents as a firm nodularity on the palmar surface of the hand with coalescing cords of soft tissue on the webs and digits." | 1.37 | Management of Dupuytren contracture with ultrasound-guided lidocaine injection and needle aponeurotomy coupled with osteopathic manipulative treatment. ( Aufiero, D; Meng, M; Montenegro, R; Sampson, S; Schulte, A; Trainor, D, 2011) |
| "Dupuytren's contracture is a common hand problem." | 1.33 | Dupuytren's fasciectomies in 60 consecutive digits using lidocaine with epinephrine and no tourniquet. ( Denkler, K, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (20.00) | 18.7374 |
| 1990's | 4 (26.67) | 18.2507 |
| 2000's | 4 (26.67) | 29.6817 |
| 2010's | 3 (20.00) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Noureddine, H | 1 |
| Vejsbjerg, K | 1 |
| Harrop, JE | 1 |
| White, MJ | 1 |
| Chakravarthy, J | 1 |
| Harrison, JWK | 1 |
| Schechtman, AD | 1 |
| Sampson, S | 1 |
| Meng, M | 1 |
| Schulte, A | 1 |
| Trainor, D | 1 |
| Montenegro, R | 1 |
| Aufiero, D | 1 |
| Sibbitt, WL | 1 |
| Michael, AA | 1 |
| Poole, JL | 1 |
| Chavez-Chiang, NR | 1 |
| Delea, SL | 1 |
| Bankhurst, AD | 1 |
| Tate, R | 1 |
| Mackay, D | 1 |
| Broome, G | 1 |
| Badalamente, MA | 1 |
| Hurst, LC | 1 |
| Hentz, VR | 1 |
| CORNAGLIA, C | 1 |
| DANIELI, GG | 1 |
| VERNONI, S | 1 |
| Denkler, K | 1 |
| Reuben, SS | 1 |
| Pristas, R | 1 |
| Dixon, D | 1 |
| Faruqi, S | 1 |
| Madabhushi, L | 1 |
| Wenner, S | 1 |
| Robins, RH | 1 |
| Scott, TD | 1 |
| Griffiths, DP | 1 |
| Bouaziz, H | 1 |
| Narchi, P | 1 |
| Mercier, FJ | 1 |
| Khoury, A | 1 |
| Poirier, T | 1 |
| Benhamou, D | 1 |
| McCarthy, DM | 1 |
| Gandy, CL | 1 |
| Cramer, A | 1 |
| Dupont, C | 1 |
| Ciaburro, H | 1 |
| Prévost, Y | 1 |
| Cloutier, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized Controlled Trial of the Reciprocating Procedure Device Versus the Conventional Syringe in Syringe-and-Needle Procedures[NCT00651625] | 437 participants (Actual) | Interventional | 2004-11-30 | Completed | |||
| Double-blind, Randomized Placebo Controlled Study of the Relative Safety and Efficacy of Collagenase Therapy in the Treatment of Residual-type Dupuytren's Disease.[NCT00260429] | Phase 3 | 38 participants (Actual) | Interventional | 2003-06-30 | Completed | ||
| Collagenase and Needle Aponeurotomy: Single Modality Versus Combination Treatment for Dupuytren's Disease[NCT01776892] | Phase 3 | 0 participants (Actual) | Interventional | 2013-05-31 | Withdrawn | ||
| Effectiveness of Distal Peripheral Nerve Blocks on Postoperative Pain Management After Ambulatory Thumb Resection Arthroplasty.[NCT01597479] | Phase 4 | 52 participants (Actual) | Interventional | 2012-02-29 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT00651625)
Timeframe: during procedure, 2 weeks afterwards, and 6 months afterwards
| Intervention | participants (Number) |
|---|---|
| 1Conventional Syringe | 0 |
| 2RPD Syringe | 0 |
Aspirated fluid volume during procedure (NCT00651625)
Timeframe: during procedure
| Intervention | ml (Mean) |
|---|---|
| 1Conventional Syringe | 7.2 |
| 2RPD Syringe | 14.5 |
0-10 cm VAS pain scale at 2 weeks compared to 0-10 cm VAS pain scale at 0 weeks where 0= no pain, and 10 = the worst pain imaginable. The difference (2 week VAS-0 week VAS) is the primary outcome measure. (NCT00651625)
Timeframe: 2 weeks
| Intervention | cm (Mean) |
|---|---|
| 1Conventional Syringe | 5.2 |
| 2RPD Syringe | 6.2 |
"0- 10 cm visual analogue satisfaction scale (VASS)~0-10 cm VASS at 2 weeks compared to 0-10 cm VASS pain scale at 0 weeks where 0= completely dissatisfied, and 10 = completely satsified. The difference (2 week VAS-0 week VAS) is the outcome measure" (NCT00651625)
Timeframe: during procedure
| Intervention | cm (Mean) |
|---|---|
| 1Conventional Syringe | 6.4 |
| 2RPD Syringe | 8.5 |
"The Primary Outcome Measure for patients treated with AA4500 is the percentage of 23 joints that were successfully treated where successfully treated was defined as reduction in contracture to 5° or less.~The Primary Outcome Measure for placebo treated patients is the percentage of 12 joints that were successfully treated where successfully treated was defined as reduction in contracture to 5° or less." (NCT00260429)
Timeframe: 30 days after the last injection
| Intervention | % Joints (Number) |
|---|---|
| AA4500 | 91.3 |
| Placebo | 0 |
Number of participants with Maximum pain intensity NVS > 3; Rescue analgesia; Nausea and Vomiting incidence; use of ondansetron for NVPO; Ondansetron being effective (number of participants for whom ondansetron was effective to stop NVPO). (NCT01597479)
Timeframe: Up to 48 hours
| Intervention | participants (Number) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Maximum pain intensity 24h (NVS>3) | Maximum pain intensity 48h (NVS >3) | Rescue analgesia 24h (n) | Rescue Analgesia 48h (n) | Nausea and vomiting 24h (n) | Nausea and vomiting 48h (n) | Use of ondansetron 24h (n) | Use of ondansetron 48h (n) | Effectiveness of ondansetron 24h | Efectiveness of ondansetron 48h | |
| dPNBs Group | 8 | 5 | 2 | 5 | 1 | 0 | 1 | 0 | 1 | 0 |
| Non dPNBs Group | 24 | 21 | 17 | 17 | 10 | 5 | 5 | 5 | 4 | 2 |
Pain scores assessed using pain numerical visual scale (NVS) of 0-10 (o= no pain and 10= worst pain imaginable). We defined mild pain (NVS 0-3); moderate pain (NVS 4-6) and severe pain (NVS 7-10).The analysis of this variable at the end of the study will confirm or not the effectiveness of dPNBs for management of postoperative pain after TRA. (NCT01597479)
Timeframe: Up to 48 hours
| Intervention | percentage of patients (Number) | |
|---|---|---|
| Pain intensity NVS>3 on call 24h | Pain intensity NVS>3 on call 48h | |
| Distal Peripheral Nerve Blocks Group (dPNBs Group) | 8.3 | 4.2 |
| Non Distal Peripheral Nerve Blocks (Non dPNBs Group) | 80.8 | 42.3 |
1 review available for lidocaine and Dupuytren Contracture
| Article | Year |
|---|---|
Anesthesia for Dupuytren's contracture.
Topics: Anesthesia, General; Brachial Plexus; Bupivacaine; Contraindications; Dupuytren Contracture; Humans; | 1991 |
3 trials available for lidocaine and Dupuytren Contracture
| Article | Year |
|---|---|
Nerve blocks at the wrist for painful injections of the palm.
Topics: Adrenal Cortex Hormones; Adult; Anesthetics, Local; Dupuytren Contracture; Female; Hand; Humans; Inj | 2011 |
Collagen as a clinical target: nonoperative treatment of Dupuytren's disease.
Topics: Aged; Analysis of Variance; Anesthetics, Local; Clostridium; Dose-Response Relationship, Drug; Doubl | 2002 |
Collagen as a clinical target: nonoperative treatment of Dupuytren's disease.
Topics: Aged; Analysis of Variance; Anesthetics, Local; Clostridium; Dose-Response Relationship, Drug; Doubl | 2002 |
Collagen as a clinical target: nonoperative treatment of Dupuytren's disease.
Topics: Aged; Analysis of Variance; Anesthetics, Local; Clostridium; Dose-Response Relationship, Drug; Doubl | 2002 |
Collagen as a clinical target: nonoperative treatment of Dupuytren's disease.
Topics: Aged; Analysis of Variance; Anesthetics, Local; Clostridium; Dose-Response Relationship, Drug; Doubl | 2002 |
The use of a selective axillary nerve block for outpatient hand surgery.
Topics: Ambulatory Surgical Procedures; Analgesia; Anesthesia Recovery Period; Anesthetics, Local; Axilla; B | 1998 |
11 other studies available for lidocaine and Dupuytren Contracture
| Article | Year |
|---|---|
Fasciectomy under local anaesthetic and adrenaline for Dupuytren's contracture in a community setting in the UK with a cost analysis.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Costs and Cost Analysis; Dupu | 2020 |
Combining triamcinolone and lidocaine for soft tissue injections.
Topics: Anesthetics, Local; Chemical Precipitation; Drug Combinations; Drug Therapy, Combination; Dupuytren | 2008 |
Management of Dupuytren contracture with ultrasound-guided lidocaine injection and needle aponeurotomy coupled with osteopathic manipulative treatment.
Topics: Dupuytren Contracture; Fascia; Fasciotomy; Female; Humans; Injections, Intramuscular; Lidocaine; Man | 2011 |
A prospective study of limited palmar and digital fasciectomy under local anaesthetic wrist block and upper arm tourniquet.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Bupivacaine; Dupuytren Contracture; Fasciotomy; | 2011 |
[OUR EXPERIENCE WITH REGIONAL ANESTHESIA, USING INTRAVENOUS ADMINISTRATION].
Topics: Administration, Intravenous; Anesthesia; Anesthesia, Conduction; Anesthesia, Intravenous; Cellulitis | 1963 |
Dupuytren's fasciectomies in 60 consecutive digits using lidocaine with epinephrine and no tourniquet.
Topics: Adult; Aged; Ambulatory Surgical Procedures; Anesthetics, Local; Dupuytren Contracture; Epinephrine; | 2005 |
The incidence of complex regional pain syndrome after fasciectomy for Dupuytren's contracture: a prospective observational study of four anesthetic techniques.
Topics: Aged; Anesthesia; Anesthesia, Conduction; Anesthesia, General; Anesthesia, Intravenous; Arm; Axilla; | 2006 |
Day care surgery for Dupuytren's contracture.
Topics: Adult; Aged; Ambulatory Surgical Procedures; Anesthesia, Conduction; Bupivacaine; Cost Control; Dupu | 1993 |
The long-term results of enzymic fasciotomy.
Topics: Dupuytren Contracture; Fascia; Humans; Hyaluronoglucosaminidase; Lidocaine; Middle Aged; Recurrence; | 1992 |
[Letter: Infiltration therapy of Dupuytren's contracture].
Topics: Dupuytren Contracture; Humans; Injections; Lidocaine | 1973 |
Hand surgery under wrist block and local infiltration anesthesia, using an upper arm tourniquet.
Topics: Anesthesia, Local; Dupuytren Contracture; Epinephrine; Hand; Humans; Lidocaine; Nerve Compression Sy | 1972 |