lidocaine has been researched along with Drug Overdose in 52 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We attempted to clarify this issue by comparing the clinical course of methemoglobinemia caused by dapsone and that caused by other toxic agents." | 7.83 | Difference of the clinical course and outcome between dapsone-induced methemoglobinemia and other toxic-agent-induced methemoglobinemia. ( Ahn, S; Kim, WY; Kim, YJ; Lee, JH; Lee, YS; Lim, KS; Oh, BJ; Ryoo, SM; Seo, DW; Sohn, CH, 2016) |
| "We report a case of neonatal seizures after lidocaine administration for circumcision." | 7.74 | Generalized seizures following topical lidocaine administration during circumcision: establishing causation. ( Finkelstein, Y; Koren, G; Railton, C; Rezvani, M; Verjee, Z, 2007) |
| "Torsade de pointes is a polymorphic ventricular tachyarrhythmia associated with a long QT interval." | 6.40 | Torsade de pointes with sotalol overdose treated successfully with lidocaine. ( Assimes, TL; Malcolm, I, 1998) |
| "Bupropion is an atypical antidepressant often used in the treatment of depression, tobacco cessation, seasonal affective disorder, and off label for ADHD." | 5.72 | Treatment of status epilepticus and prolonged QT after massive intentional bupropion overdose with lidocaine. ( Robinson, S, 2022) |
| "Amantadine hydrochloride is a commonly prescribed drug with a narrow therapeutic-to-toxic range." | 5.28 | Amantadine toxicity presenting with complex ventricular ectopy and hallucinations. ( Hughes, B; Pimentel, L, 1991) |
| "We attempted to clarify this issue by comparing the clinical course of methemoglobinemia caused by dapsone and that caused by other toxic agents." | 3.83 | Difference of the clinical course and outcome between dapsone-induced methemoglobinemia and other toxic-agent-induced methemoglobinemia. ( Ahn, S; Kim, WY; Kim, YJ; Lee, JH; Lee, YS; Lim, KS; Oh, BJ; Ryoo, SM; Seo, DW; Sohn, CH, 2016) |
| "The purpose of the present study is to determine the role of lidocaine, caffeine and dextromethorphan, used as adulterant substances, in five cases of drug overdose which have come to our attention." | 3.79 | The pathogenetic role of adulterants in 5 cases of drug addicts with a fatal outcome. ( Barbera, N; Busardò, FP; Indorato, F; Romano, G, 2013) |
| "We report a case of neonatal seizures after lidocaine administration for circumcision." | 3.74 | Generalized seizures following topical lidocaine administration during circumcision: establishing causation. ( Finkelstein, Y; Koren, G; Railton, C; Rezvani, M; Verjee, Z, 2007) |
| "We treated an 88-year-old man with aortic valvular stenosis/insufficiency and paroxysmal atrial fibrillation, who developed ventricular tachycardia due to pilsicainide toxicity." | 3.72 | A case of the toxicity of pilsicainide hydrochloride with comparison of the serial serum pilsicainide levels and electrocardiographic findings. ( Funada, A; Horita, Y; Kaku, B; Kanaya, H; Kitajima, S; Matsumura, M; Satoh, T; Uno, Y; Yamazaki, T, 2004) |
| "A 19-year-old woman presented with status epilepticus and ventricular dysrhythmias less than one hour after ingesting 5,000 mg dimenhydrinate (Dramamine)." | 3.68 | Fatality secondary to massive overdose of dimenhydrinate. ( McDonnell, KP; Winn, RE, 1993) |
| "The development of safe and effective local anesthetic agents has possibly been the most important advancement in dental science to occur in the last century." | 2.46 | Local anesthetics: pharmacology and toxicity. ( Hersh, EV; Moore, PA, 2010) |
| "Lidocaine was detected in the subject's urine through immunoenzymatic screening." | 2.44 | Suicide due to oral ingestion of lidocaine: a case report and review of the literature. ( Centini, F; Fineschi, V; Fiore, C; Riezzo, I; Rossi, G, 2007) |
| "Torsade de pointes is a polymorphic ventricular tachyarrhythmia associated with a long QT interval." | 2.40 | Torsade de pointes with sotalol overdose treated successfully with lidocaine. ( Assimes, TL; Malcolm, I, 1998) |
| "Lidocaine should not be used to treat painful mouth lesions in children until further safety data are available." | 2.39 | Lidocaine overdose: another preventable case? ( Druckenbrod, RW; Gonzalez del Rey, J; Wason, S, 1994) |
| "Bupropion is an atypical antidepressant often used in the treatment of depression, tobacco cessation, seasonal affective disorder, and off label for ADHD." | 1.72 | Treatment of status epilepticus and prolonged QT after massive intentional bupropion overdose with lidocaine. ( Robinson, S, 2022) |
| "Citalopram overdose may produce bradycardia, QT prolongation, and torsades de pointes (TdP)." | 1.35 | Citalopram overdose: late presentation of torsades de pointes (TdP) with cardiac arrest. ( Hoffman, RS; Nelson, L; Tarabar, AF, 2008) |
| "Caffeine overdoses produce multiple symptoms, most of which are commonly associated with a marked increase in adrenergic tone." | 1.35 | Treatment of cardiovascular collapse from caffeine overdose with lidocaine, phenylephrine, and hemodialysis. ( Kapur, R; Smith, MD, 2009) |
| "As electrocardiography (ECG) revealed ventricular tachycardia (VT), cardioversion was administered but was unsuccessful." | 1.33 | [Case in which magnesium sulfate effectively treated ventricular tachycardia due to overdose of pilsicainide hydrochloride]. ( Mato, T; Moriwaki, R; Nakata, K; Takenouchi, S; Tsutsumi, H; Yamaguchi, A, 2006) |
| " They have apparently safe cardiac safety profiles in both therapeutic and supratherapeutic doses, but recently the Federal Drug Administration has issued a caution regarding ziprasidone use in combination with other drugs that are known to prolong the QTc interval." | 1.32 | Cardiotoxicity associated with intentional ziprasidone and bupropion overdose. ( Biswas, AK; Mayes, KL; Morris-Kukoski, CL; Zabrocki, LA, 2003) |
| " The number of adverse reactions reported, particularly toxic reactions, are extraordinarily negligible." | 1.30 | Lidocaine toxicity. ( Caiazzo, A; Maloney, P; Mehra, P, 1998) |
| "Amantadine hydrochloride is a commonly prescribed drug with a narrow therapeutic-to-toxic range." | 1.28 | Amantadine toxicity presenting with complex ventricular ectopy and hallucinations. ( Hughes, B; Pimentel, L, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 16 (30.77) | 18.2507 |
| 2000's | 21 (40.38) | 29.6817 |
| 2010's | 13 (25.00) | 24.3611 |
| 2020's | 2 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Robinson, S | 1 |
| Zhu, E | 1 |
| Gabriele, M | 1 |
| Nguyen, MT | 1 |
| Szadkowski, M | 1 |
| Drapkin, Z | 1 |
| Hewes, H | 1 |
| Caravati, EM | 1 |
| Plumb, J | 1 |
| Fukasawa, M | 1 |
| Ninomiya, K | 1 |
| Kawakami, Y | 1 |
| Fuke, C | 1 |
| Miyazaki, T | 1 |
| Sullivan, RW | 1 |
| Ryzewski, M | 1 |
| Holland, MG | 1 |
| Marraffa, JM | 1 |
| Bhupali, C | 1 |
| Cummings, BM | 1 |
| Parker, L | 1 |
| Young, R | 1 |
| Noviski, N | 1 |
| Weaver, JM | 2 |
| Hoda, S | 1 |
| O'Brien, J | 1 |
| Gamble, J | 1 |
| Kim, YJ | 1 |
| Sohn, CH | 1 |
| Ryoo, SM | 1 |
| Ahn, S | 1 |
| Seo, DW | 1 |
| Lee, YS | 1 |
| Lee, JH | 1 |
| Oh, BJ | 1 |
| Lim, KS | 1 |
| Kim, WY | 1 |
| Tarabar, AF | 1 |
| Hoffman, RS | 1 |
| Nelson, L | 1 |
| Kapur, R | 1 |
| Smith, MD | 1 |
| Moore, PA | 1 |
| Hersh, EV | 1 |
| Gordh, T | 1 |
| Thyen, AB | 1 |
| McAllister, RK | 1 |
| Councilman, LM | 1 |
| Barbera, N | 1 |
| Busardò, FP | 1 |
| Indorato, F | 1 |
| Romano, G | 1 |
| Lange, DB | 1 |
| Schwartz, D | 1 |
| DaRoza, G | 1 |
| Gair, R | 1 |
| Schmitt, C | 1 |
| Matulic, M | 1 |
| Kervégant, M | 1 |
| Tichadou, L | 1 |
| Boutin, A | 1 |
| Glaizal, M | 1 |
| de Haro, L | 1 |
| Berger, I | 1 |
| Steinberg, A | 1 |
| Schlesinger, Y | 1 |
| Seelenfreund, M | 1 |
| Schimmel, MS | 1 |
| Kalin, JR | 1 |
| Brissie, RM | 1 |
| Koerner, KR | 1 |
| Taylor, SE | 1 |
| Biswas, AK | 1 |
| Zabrocki, LA | 1 |
| Mayes, KL | 1 |
| Morris-Kukoski, CL | 1 |
| Kudo, K | 1 |
| Nishida, N | 1 |
| Kiyoshima, A | 1 |
| Ikeda, N | 1 |
| Horita, Y | 1 |
| Kanaya, H | 1 |
| Uno, Y | 1 |
| Yamazaki, T | 1 |
| Kaku, B | 1 |
| Funada, A | 1 |
| Kitajima, S | 1 |
| Matsumura, M | 1 |
| Satoh, T | 1 |
| Barbaro, A | 1 |
| Kranioti, EF | 1 |
| Mavroforou, A | 1 |
| Mylonakis, P | 1 |
| Michalodimitrakis, M | 1 |
| Nakata, K | 1 |
| Moriwaki, R | 1 |
| Yamaguchi, A | 1 |
| Takenouchi, S | 1 |
| Mato, T | 1 |
| Tsutsumi, H | 1 |
| Centini, F | 1 |
| Fiore, C | 1 |
| Riezzo, I | 1 |
| Rossi, G | 1 |
| Fineschi, V | 1 |
| Rezvani, M | 1 |
| Finkelstein, Y | 1 |
| Verjee, Z | 1 |
| Railton, C | 1 |
| Koren, G | 1 |
| Kempen, PM | 1 |
| Takeuchi, S | 1 |
| Homma, M | 1 |
| Inoue, J | 1 |
| Kato, H | 1 |
| Murata, K | 1 |
| Ogasawara, T | 1 |
| Martínez, MA | 1 |
| Ballesteros, S | 1 |
| Segura, LJ | 1 |
| García, M | 1 |
| Jha, SK | 1 |
| Kumar, R | 1 |
| Verma, BS | 1 |
| Gonzalez del Rey, J | 1 |
| Wason, S | 1 |
| Druckenbrod, RW | 1 |
| Winn, RE | 1 |
| McDonnell, KP | 1 |
| Butterworth, J | 2 |
| James, RL | 2 |
| Grimes, J | 1 |
| Meechan, J | 1 |
| Assimes, TL | 1 |
| Malcolm, I | 1 |
| Avery, JK | 1 |
| Mehra, P | 1 |
| Caiazzo, A | 1 |
| Maloney, P | 1 |
| de Jong, RH | 1 |
| Grazer, FM | 1 |
| Groban, L | 1 |
| Deal, DD | 1 |
| Vernon, JC | 1 |
| Obiechina, AE | 1 |
| Oji, C | 1 |
| Meyer, GA | 1 |
| Lin, HC | 1 |
| Hanson, RR | 1 |
| Hayes, TL | 1 |
| Nisse, P | 1 |
| Lhermitte, M | 1 |
| Dherbecourt, V | 1 |
| Fourier, C | 1 |
| Leclerc, F | 1 |
| Houdret, N | 1 |
| Mathieu-Nolf, M | 1 |
| Bruguerolle, B | 1 |
| Emperaire, N | 1 |
| Nichols, GR | 1 |
| Davis, GJ | 1 |
| Collee, GG | 1 |
| Samra, GS | 1 |
| Hanson, GC | 1 |
| Palmisano, JM | 1 |
| Meliones, JN | 1 |
| Crowley, DC | 1 |
| Martin, JM | 1 |
| Truman, KH | 1 |
| Krauzowicz, BA | 1 |
| Rocchini, AP | 1 |
| Pimentel, L | 1 |
| Hughes, B | 1 |
| Normand de La Tranchade, M | 1 |
| Maurisset, O | 1 |
| Jonville, AP | 1 |
| Barbier, P | 1 |
| Blond, MH | 1 |
| Boscq, M | 1 |
| Autret, E | 1 |
| Breteau, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Antipruritic Effect of Topical Ketamine, Amitriptyline, and Lidocaine[NCT03096444] | Phase 2 | 13 participants (Actual) | Interventional | 2017-05-23 | Terminated (stopped due to Efficacy was not seen after interim analysis) | ||
| Intravenous Lidocaine for Postoperative Recovery in Liver Surgery, a Randomized Double Blinded Placebo-controlled Study[NCT05153785] | Phase 2/Phase 3 | 80 participants (Anticipated) | Interventional | 2021-11-15 | Recruiting | ||
| Methemoglobin Levels in Generally Anesthetized Pediatric Dental Patients Receiving Prilocaine Versus Lidocaine[NCT01402869] | 91 participants (Actual) | Interventional | 2011-08-31 | Completed | |||
| Safety of Local Dental Anesthesia in Patients With Cardiac Channelopathies[NCT03182777] | 31 participants (Actual) | Interventional | 2015-05-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Peak itch intensity between the vehicle and 4 other active treatments (individual ketamine, amitriptyline, or lidocaine, and KeAmLi-combo). Itch intensity was measured on a 100mm scale visual analog scale for 10 minutes. 0 was weighted with no itch and 100 was weighted with most itch imaginable." (NCT03096444)
Timeframe: 10 minutes
| Intervention | Intensity score (Mean) |
|---|---|
| Topical KeAmLi Combo | 62.7 |
| Topical Ketamine | 63.1 |
| Topical Amitriptyline | 69.2 |
| Topical Lidocaine | 65.8 |
| Topical Vehicle | 61.9 |
Assess mechanical detection and pain thresholds using von Frey filaments stimulators (measured in force mN) to calculate the final threshold as the geometric mean of five series of ascending and descending stimuli. (NCT03096444)
Timeframe: 5 minutes
| Intervention | mN (Mean) | |
|---|---|---|
| Mechanical Detection Threshold | Mechanical Pain Threshold | |
| Topical Amitriptyline | 3.573423965 | 152.4768146 |
| Topical KeAmLi Combo | 3.519376956 | 152.3293608 |
| Topical Ketamine | 3.464204768 | 135.9 |
| Topical Lidocaine | 3.546037659 | 126.9 |
| Topical Vehicle | 3.525692637 | 148.7138273 |
Two standardized quantitative sensory tests are performed to measure warmth detection threshold (assesses the threshold of which warmth sensation is first detected) and heat pain threshold (assesses the threshold at which heat pain sensation is first detected). Measured in change in celsius. (NCT03096444)
Timeframe: 3 minutes
| Intervention | Degrees celsius (Mean) | |
|---|---|---|
| Warm Detection Threshold | Heat Pain Threshold | |
| Topical Amitriptyline | 33.9 | 40.0 |
| Topical KeAmLi Combo | 33.6 | 39.8 |
| Topical Ketamine | 34.0 | 40.0 |
| Topical Lidocaine | 33.7 | 39.4 |
| Topical Vehicle | 33.8 | 39.7 |
Change in percentage of methemoglobin in blood from baseline level to peak level (NCT01402869)
Timeframe: From administration of local anesthetic or start of restorative procedures to time at which maximum methemoglobin blood level was documented during dental treatment for an average of 2 hours
| Intervention | percentage of methemoglobin in blood (Mean) |
|---|---|
| Prilocaine | 2.73 |
| Lidocaine | 0.78 |
| No Local Anesthetic | 0.76 |
The maximum percentage of methemoglobin in blood (NCT01402869)
Timeframe: Measured at 10 second intervals during dental treatment for an average of 2 hours
| Intervention | percentage of methemoglobin in blood (Mean) |
|---|---|
| Prilocaine | 3.55 |
| Lidocaine | 1.63 |
| No Local Anesthetic | 1.60 |
The length of time between the administration of local anesthetic (Prilocaine and Lidocaine Groups) or start of restorative dental procedures (No local anesthetic Group) and the time at which the maximum methemoglobin blood level is observed. (NCT01402869)
Timeframe: Measured at 10 second intervals during dental treatment for an average of 2 hours
| Intervention | minutes (Mean) |
|---|---|
| Prilocaine | 62.73 |
| Lidocaine | 57.50 |
| No Local Anesthetic | 29.50 |
6 reviews available for lidocaine and Drug Overdose
| Article | Year |
|---|---|
Pilsicainide Poisoning: An Autopsy Case and Review of Literature.
Topics: Accidents; Anti-Arrhythmia Agents; Drug Overdose; Humans; Lidocaine; Male; Middle Aged | 2018 |
Local anesthetics: pharmacology and toxicity.
Topics: Anesthesia, Dental; Anesthetics, Local; Bupivacaine; Carticaine; Drug Overdose; Humans; Hydrogen-Ion | 2010 |
Local anesthetics: pharmacology and toxicity.
Topics: Anesthesia, Dental; Anesthetics, Local; Bupivacaine; Carticaine; Drug Overdose; Humans; Hydrogen-Ion | 2010 |
Local anesthetics: pharmacology and toxicity.
Topics: Anesthesia, Dental; Anesthetics, Local; Bupivacaine; Carticaine; Drug Overdose; Humans; Hydrogen-Ion | 2010 |
Local anesthetics: pharmacology and toxicity.
Topics: Anesthesia, Dental; Anesthetics, Local; Bupivacaine; Carticaine; Drug Overdose; Humans; Hydrogen-Ion | 2010 |
Lethal self administration of propofol (Diprivan). A case report and review of the literature.
Topics: Adult; Anesthetics, Intravenous; Anesthetics, Local; Drug Overdose; Female; Humans; Lidocaine; Liver | 2007 |
Suicide due to oral ingestion of lidocaine: a case report and review of the literature.
Topics: Administration, Oral; Adult; Anesthetics, Local; Drug Overdose; Female; Forensic Toxicology; Gas Chr | 2007 |
Lidocaine overdose: another preventable case?
Topics: Acute Disease; Administration, Topical; Drug Overdose; Humans; Infant; Infant, Newborn; Lidocaine; M | 1994 |
Torsade de pointes with sotalol overdose treated successfully with lidocaine.
Topics: Adrenergic beta-Antagonists; Aged; Anti-Arrhythmia Agents; Drug Overdose; Electrocardiography; Follo | 1998 |
46 other studies available for lidocaine and Drug Overdose
| Article | Year |
|---|---|
Treatment of status epilepticus and prolonged QT after massive intentional bupropion overdose with lidocaine.
Topics: Adolescent; Antidepressive Agents, Second-Generation; Bupropion; Cardiotoxicity; Drug Overdose; Fema | 2022 |
The Use of Intravenous Lidocaine in the Setting of Chronic Dofetilide Overdose: A Case Report.
Topics: Alcoholism; Drug Overdose; Electrocardiography; Humans; Lidocaine; Long QT Syndrome; Substance Withd | 2022 |
A Teenager With Seizures and Cardiac Arrest After Drug Overdose: Are We Numb to the Danger?
Topics: Adolescent; Anesthetics, Local; Arrhythmias, Cardiac; Drug Overdose; Electrocardiography; Fatal Outc | 2017 |
Compounded ointment results in severe toxicity in a pediatric patient.
Topics: Administration, Cutaneous; Amines; Analgesics; Body Surface Area; Bradycardia; Clonidine; Combined M | 2013 |
Positive lidocaine toxicology screen after J-Tip for venipuncture.
Topics: Anesthetics, Local; Child, Preschool; Clonazepam; Consciousness Disorders; Drug Overdose; Emergency | 2013 |
When can a normal dose be an overdose? Who is at risk?
Topics: Adjuvants, Anesthesia; Age Factors; Anesthetics, Local; Conscious Sedation; Dose-Response Relationsh | 2014 |
Intractable seizures in a toddler after application of an over-the-counter local anesthetic cream.
Topics: Administration, Cutaneous; Anesthetics, Local; Bandages; Burns; Drug Overdose; Emergency Service, Ho | 2016 |
Difference of the clinical course and outcome between dapsone-induced methemoglobinemia and other toxic-agent-induced methemoglobinemia.
Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Dapsone; Dose-Response Relationship, Drug; Dru | 2016 |
Citalopram overdose: late presentation of torsades de pointes (TdP) with cardiac arrest.
Topics: Adult; Anti-Arrhythmia Agents; Antidepressive Agents, Second-Generation; Citalopram; Drug Overdose; | 2008 |
Treatment of cardiovascular collapse from caffeine overdose with lidocaine, phenylephrine, and hemodialysis.
Topics: Adolescent; Anti-Arrhythmia Agents; Caffeine; Cardiotonic Agents; Combined Modality Therapy; Drug Ov | 2009 |
Lidocaine: the origin of a modern local anesthetic. 1949.
Topics: Anesthesia, Conduction; Anesthesia, Local; Anesthetics, Local; Drug Discovery; Drug Overdose; Histor | 2010 |
Epidural pump programming error leading to inadvertent 10-fold dosing error during epidural labor analgesia with ropivacaine.
Topics: Adult; Amides; Analgesia, Epidural; Anesthetics, Local; Drug Overdose; Drug-Related Side Effects and | 2010 |
The pathogenetic role of adulterants in 5 cases of drug addicts with a fatal outcome.
Topics: Adult; Anesthetics, Local; Antitussive Agents; Bile; Brain Chemistry; Caffeine; Central Nervous Syst | 2013 |
Use of intravenous lipid emulsion to reverse central nervous system toxicity of an iatrogenic local anesthetic overdose in a patient on peritoneal dialysis.
Topics: Adult; Anesthetics, Local; Central Nervous System Diseases; Drug Overdose; Fat Emulsions, Intravenou | 2012 |
[Methaemoglobinaemia in a child treated with Emla(®) cream: circumstances and consequences of overdose].
Topics: Anesthetics, Combined; Child, Preschool; Dosage Forms; Drug Overdose; Female; Humans; Lidocaine; Lid | 2012 |
Neonatal mydriasis: intravenous lidocaine adverse reaction.
Topics: Anti-Arrhythmia Agents; Anticonvulsants; Diagnosis, Differential; Drug Overdose; Drug Therapy, Combi | 2002 |
A case of homicide by lethal injection with lidocaine.
Topics: Adult; Anesthetics, Local; Arrhythmias, Cardiac; Cause of Death; Drug Overdose; Homicide; Humans; Li | 2002 |
Emergencies associated with local anesthetics.
Topics: Adolescent; Adult; Akathisia, Drug-Induced; Anesthesia, Dental; Anesthetics, Local; Brain; Child, Pr | 2000 |
Cardiotoxicity associated with intentional ziprasidone and bupropion overdose.
Topics: Adolescent; Anti-Arrhythmia Agents; Antidepressive Agents, Second-Generation; Antipsychotic Agents; | 2003 |
A fatal case of poisoning by lidocaine overdosage--analysis of lidocaine in formalin-fixed tissues: a case report.
Topics: Aged; Animals; Anti-Arrhythmia Agents; Brain Chemistry; Drug Overdose; Fatal Outcome; Fixatives; For | 2004 |
A case of the toxicity of pilsicainide hydrochloride with comparison of the serial serum pilsicainide levels and electrocardiographic findings.
Topics: Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Creatinine; Drug Overdose; Ele | 2004 |
About an unusual case: GC-MS detection of lidocaine.
Topics: Adult; Anesthetics, Local; Arrhythmias, Cardiac; Brain Chemistry; Cocaine; Dopamine Uptake Inhibitor | 2004 |
[Case in which magnesium sulfate effectively treated ventricular tachycardia due to overdose of pilsicainide hydrochloride].
Topics: Adult; Anti-Asthmatic Agents; Drug Overdose; Hemoperfusion; Humans; Infusions, Intravenous; Lidocain | 2006 |
Calculating the maximum recommended dose of local anesthetic.
Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Body Weight; Bupivacaine; Child; Drug Interactions; D | 2007 |
Generalized seizures following topical lidocaine administration during circumcision: establishing causation.
Topics: Administration, Topical; Anesthetics, Local; Circumcision, Male; Dose-Response Relationship, Drug; D | 2007 |
Weakness following an overdose of lidocaine during general anesthesia.
Topics: Anesthesia, General; Drug Overdose; Humans; Lidocaine; Muscle Weakness | 2007 |
[Case of intractable ventricula fibrillation by a multicomponent dietary supplement containing ephedra and caffeine overdose].
Topics: Adult; Caffeine; Dietary Supplements; Drug Overdose; Drug Synergism; Electric Countershock; Ephedra; | 2007 |
Reporting a fatality during tumescent liposuction.
Topics: Adult; Ambulatory Care; Anesthetics, Local; Drug Overdose; Epilepsy, Tonic-Clonic; Epinephrine; Fata | 2008 |
A case of barium carbonate poisoning.
Topics: Adolescent; Barium; Carbonates; Cardiac Complexes, Premature; Critical Care; Drug Overdose; Electroc | 1993 |
Fatality secondary to massive overdose of dimenhydrinate.
Topics: Adult; Arrhythmias, Cardiac; Cardiopulmonary Resuscitation; Charcoal; Colon; Dimenhydrinate; Diphenh | 1993 |
Structure-affinity relationships and stereospecificity of several homologous series of local anesthetics for the beta2-adrenergic receptor.
Topics: Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Antagonists; Adult; Alkanes; Amides; Anesthe | 1997 |
How to avoid local anaesthetic toxicity.
Topics: Adult; Aged; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Body Weight; Child; Child, P | 1998 |
Routine procedure--bad outcome.
Topics: Aged; Anesthetics, Local; Bradycardia; Brain Diseases; Bronchoscopy; Drug Overdose; Heart Arrest; Hu | 1998 |
Lidocaine toxicity.
Topics: Administration, Topical; Adult; Anesthesia, Dental; Anesthetics, Local; Dose-Response Relationship, | 1998 |
"Tumescent" liposuction alert: deaths from lidocaine cardiotoxicity.
Topics: Anesthetics, Local; Cause of Death; Dose-Response Relationship, Drug; Drug Overdose; Forensic Medici | 1999 |
Ventricular arrhythmias with or without programmed electrical stimulation after incremental overdosage with lidocaine, bupivacaine, levobupivacaine, and ropivacaine.
Topics: Amides; Anesthetics, Local; Animals; Bupivacaine; Cardiac Pacing, Artificial; Dogs; Drug Overdose; L | 2000 |
Evaluation of precautions adopted by dental surgeon using local anaesthesia.
Topics: Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Drug Overdose; Female; Gloves, Surgical; | 2001 |
Effects of intravenous lidocaine overdose on cardiac electrical activity and blood pressure in the horse.
Topics: Anesthetics, Local; Animals; Behavior, Animal; Blood Pressure; Drug Overdose; Electrocardiography; F | 2001 |
[Fatal intoxication after accidental ingestion of viscous 2% lidocaine in a young child].
Topics: Administration, Oral; Anesthetics, Local; Cardiovascular System; Chromatography, High Pressure Liqui | 2002 |
Local anesthetic-induced toxicity may be modified by low doses of flumazenil.
Topics: Anesthesia, Local; Animals; Drug Overdose; Etidocaine; Flumazenil; Lidocaine; Male; Mepivacaine; Mic | 1992 |
Body packing with a twist. Death of a salesman.
Topics: Adult; Crime; Drug Overdose; Humans; Illicit Drugs; Lidocaine; Male | 1992 |
Chloroquine poisoning: ventricular fibrillation following 'trivial' overdose in a child.
Topics: Adolescent; Cardiopulmonary Resuscitation; Chloroquine; Drug Overdose; Electrocardiography; Gastric | 1992 |
Lidocaine toxicity after subcutaneous infiltration in children undergoing cardiac catheterization.
Topics: Cardiac Catheterization; Child, Preschool; Drug Overdose; Humans; Infant; Injections, Subcutaneous; | 1991 |
Amantadine toxicity presenting with complex ventricular ectopy and hallucinations.
Topics: Adolescent; Amantadine; Arrhythmias, Cardiac; Charcoal; Drug Overdose; Electrocardiography; Emergenc | 1991 |
[Reversible coma after bronchoscopy attributed to lidocaine overdose].
Topics: Bronchoscopy; Coma; Drug Overdose; Female; Humans; Lidocaine; Middle Aged | 1990 |
Accidental lidocaine overdosage in an infant.
Topics: Drug Overdose; Hemodynamics; Humans; Infant, Newborn; Injections, Intravenous; Lidocaine; Male; Medi | 1990 |