lidocaine and Drug Hypersensitivity
lidocaine has been researched along with Drug Hypersensitivity in 188 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Drug Hypersensitivity: Immunologically mediated adverse reactions to medicinal substances used legally or illegally.
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"Lidocaine hydrochloride is an amide-type local anesthetic, commonly used for facial plastic as well as other surgical procedures." | 5.27 | Anaphylactic reaction to lidocaine. ( Cave, RH; Kennedy, KS, 1986) |
" The diphenhydramine median pain score was 55 mm, compared with 12." | 5.08 | Randomized trial of diphenhydramine versus benzyl alcohol with epinephrine as an alternative to lidocaine local anesthesia. ( Bartfield, JM; Jandreau, SW; Raccio-Robak, N, 1998) |
" We discuss the literature that has influenced current office behavior regarding endocarditis prophylaxis, the use of electrosurgery with pacemakers, arrhythmogenic drug interactions, vasovagal syncope, lidocaine "allergy," and bleeding complications from oral anticoagulants." | 4.79 | Medical issues and emergencies in the dermatology office. ( Fader, DJ; Johnson, TM, 1997) |
" On the second occasion, he received only sevoflurane and presented anaphylaxis, treated with intramuscular adrenaline." | 4.31 | [Anafilaxia perioperatoria a sevoflurano, un caso muy raro]. ( González-Vallejo, AG; Hernandez-López, E, 2023) |
"Allergic contact dermatitis (ACD) to lidocaine is rising in prevalence." | 3.80 | Lidocaine contact allergy is becoming more prevalent. ( de Gannes, G; Kossintseva, I; To, D, 2014) |
"We report a rare case of hypersensitivity in a 63-year-old man who received subconjunctival lidocaine, cefazolin, and gentamicin for corneal abscess." | 3.73 | Lidocaine hypersensitivity after subconjunctival injection. ( Levy, J; Lifshitz, T, 2006) |
"A 43-year-old woman with a history of lidocaine allergy required dermatologic surgery during pregnancy." | 3.71 | A pregnant woman with previous anaphylactic reaction to local anesthetics: a case report. ( Birnbach, DJ; Browne, IM, 2001) |
"The patient described here experienced an acute anaphylactic reaction after receiving parenteral lidocaine, oral aspirin, codeine, and penicillin following routine dental treatment." | 3.66 | Dental drugs and anaphylactic reactions. Report of a case. ( Gill, C; Michaelides, PL, 1980) |
"A 39-year-old man developed allergic hypersensitivity to lidocaine hydrochloride and showed urticarial dermographism." | 3.66 | Allergic hypersensitivity to lidocaine hydrochloride. ( Chin, TM; Fellner, MJ, 1980) |
"A 38-year-old white woman developed left medical rectus myositis possibly due to an immune response to mepivacaine (Carbocaine) injected around her upper left first molar." | 3.66 | Vertical pendular nystagmus in chronic myositis of medial and lateral rectus. ( Goldberg, RT, 1978) |
"However type I hypersensitivity to lignocaine is rare and there have been very few cases reported in the literature." | 1.33 | IgE-mediated hypersensitivity reaction to lignocaine - a case report. ( Gendeh, BS; Mujahid, SH; Noormalin, A; Rosmilah, M; Shahnaz, M, 2005) |
"Lidocaine is an anaesthetic agent used worldwide in various clinical specialties." | 1.32 | Evaluation of re-challenge in patients with suspected lidocaine allergy. ( Amsler, E; Aractingi, S; Flahault, A; Mathelier-Fusade, P, 2004) |
"Patients with drug allergy show a specific immune response to drugs." | 1.30 | Recognition of local anesthetics by alphabeta+ T cells. ( Hari, Y; Pichler, WJ; Schnyder, B; von Greyerz, S; Zanni, MP, 1999) |
"A young woman was found to have a true type I hypersensitivity to lignocaine." | 1.30 | Allergic reactions to lignocaine. ( Ball, IA, 1999) |
"In 87 of the 90 patients with suspected anaphylactoid reactions to local anesthetic agents, negative skin reactions to at least one of the agents allowed intrabuccal challenge and subsequent recommendation of an agent for future use." | 1.29 | Skin testing after anaphylactoid reactions to dental local anesthetics. A comparison with controls. ( Challacombe, SJ; Hodgson, TA; Shirlaw, PJ, 1993) |
"Tocainide is a primary analog of lidocaine with antiarrhythmic properties used to treat ventricular rhythm disorders." | 1.27 | Tocainide: a severe adverse reaction. ( DeSimone, A; Dunn, JM; Groth, PE, 1988) |
" We retrospectively reviewed all our consultations for evaluation of local anesthetic allergy from 1965 to 1985 to assess the safety and efficacy of skin testing and provocative test dosing with a variety of local anesthetic agents." | 1.27 | Provocative challenge with local anesthetics in patients with a prior history of reaction. ( Chandler, MJ; Grammer, LC; Patterson, R, 1987) |
"Lidocaine hydrochloride is an amide-type local anesthetic, commonly used for facial plastic as well as other surgical procedures." | 1.27 | Anaphylactic reaction to lidocaine. ( Cave, RH; Kennedy, KS, 1986) |
"In a study of 7 cases of adverse reactions to local anaesthetics the early symptoms of toxicity (malaise, anxiety, feeling of impending death, peripheral paresthesias and tachycardia) are reviewed." | 1.26 | [Minor toxic effects of local anaesthetics. 7 cases (author's transl)]. ( Dry, J; Leynadier, F, 1980) |
Research
Studies (188)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 97 (51.60) | 18.7374 |
1990's | 30 (15.96) | 18.2507 |
2000's | 37 (19.68) | 29.6817 |
2010's | 19 (10.11) | 24.3611 |
2020's | 5 (2.66) | 2.80 |
Authors
Authors | Studies |
---|---|
Barradas Lopes, J | 1 |
Reis Ferreira, A | 1 |
Sousa, MJ | 1 |
Cadinha, S | 1 |
González-Vallejo, AG | 1 |
Hernandez-López, E | 1 |
Carrión Sari, SK | 1 |
Lezaun, A | 1 |
Colas Sanz, C | 1 |
Selmanoglu, A | 1 |
Güvenir, H | 1 |
Celik, IK | 1 |
Karaatmaca, B | 1 |
Toyran, M | 1 |
Civelek, E | 1 |
Misirlioglu, ED | 1 |
Bahar, E | 1 |
Yoon, H | 1 |
Maxey-Jones, CL | 1 |
Palmerton, A | 1 |
Farmer, JR | 1 |
Bateman, BT | 1 |
Elkoundi, A | 1 |
Bensghir, M | 1 |
Lalaoui, SJ | 1 |
Bina, B | 1 |
Hersh, EV | 1 |
Hilario, M | 1 |
Alvarez, K | 1 |
McLaughlin, B | 1 |
Hermann, R | 1 |
Lam, F | 1 |
Spackman, G | 1 |
Kvisselgaard, AD | 1 |
Melchiors, BB | 1 |
Krøigaard, M | 1 |
Garvey, LH | 1 |
Sanan, N | 1 |
Lee, J | 1 |
Baxter, C | 1 |
Jeskey, J | 1 |
Hostoffer, R | 1 |
Dyer, JE | 1 |
Nafie, S | 1 |
Mellon, JK | 1 |
Khan, MA | 1 |
To, D | 1 |
Kossintseva, I | 1 |
de Gannes, G | 1 |
Nishi, M | 1 |
Zen, K | 1 |
Kambayashi, D | 1 |
Asada, S | 1 |
Yamaguchi, S | 1 |
Tatsukawa, H | 1 |
Thompson, TM | 1 |
Theobald, JL | 1 |
Rajalakshmi, AR | 1 |
Kumar, MA | 1 |
King, G | 1 |
Byrne, A | 1 |
Fleming, P | 1 |
Yamaguchi, T | 1 |
Nakagome, K | 1 |
Udagawa, K | 1 |
Takaku, Y | 1 |
Sato, N | 1 |
Soma, T | 1 |
Hagiwara, K | 1 |
Kanazawa, M | 1 |
Nagata, M | 1 |
Hu, WL | 1 |
Chang, CH | 1 |
Hung, YC | 1 |
Shieh, TY | 1 |
Tanboğa, IH | 1 |
Karabay, CY | 1 |
Can, MM | 1 |
Akgün, T | 1 |
Güler, A | 1 |
Turkylmaz, E | 1 |
Ozveren, O | 1 |
Kaymaz, C | 1 |
Sambrook, PJ | 1 |
Smith, W | 1 |
Elijah, J | 1 |
Goss, AN | 1 |
Kluger, N | 1 |
Raison-Peyron, N | 1 |
Michot, C | 1 |
Guillot, B | 1 |
Bessis, D | 1 |
Glück, J | 1 |
Rymarczyk, B | 1 |
Rogala, B | 1 |
Kamata, M | 1 |
Tada, Y | 1 |
Yazawa, N | 1 |
Watanabe, T | 1 |
Kikuchi, K | 1 |
Sato, S | 1 |
Becker, DE | 1 |
Reed, KL | 1 |
Kartal, O | 1 |
Gulec, M | 1 |
Caliskaner, AZ | 1 |
Sener, O | 1 |
Evans, LA | 1 |
Pointing, J | 1 |
Wills, EJ | 1 |
Michalopoulos, J | 1 |
Adelstein, S | 1 |
Knowles, SR | 1 |
Uetrecht, JP | 1 |
Shear, NH | 1 |
Hawkins, JM | 1 |
Moore, PA | 1 |
Helfman, M | 1 |
Mackley, CL | 1 |
Marks, JG | 1 |
Anderson, BE | 1 |
Calman, C | 1 |
Cox, B | 1 |
Durieux, ME | 1 |
Marcus, MA | 1 |
Kaufmann, JM | 1 |
Hale, EK | 1 |
Ashinoff, RA | 1 |
Cohen, DE | 1 |
CERCIELLO, G | 1 |
RAJKA, G | 2 |
SKOG, E | 1 |
NAGOSHI, Y | 1 |
KANEKO, Z | 1 |
UMEZAWA, S | 1 |
MICHINOSHITA, K | 1 |
YAMAMOTO, K | 1 |
NAKAI, Y | 1 |
FUKUDA, S | 1 |
AOKI, S | 1 |
MIYABE, I | 1 |
SUGIYAMA, S | 1 |
HONJO, S | 1 |
YAMADA, T | 1 |
KIMURA, S | 1 |
NAKAZAWA, A | 1 |
FURUYA, M | 1 |
HOSOGAWA, A | 1 |
KOBAYASHI, Y | 1 |
MEYER, RA | 1 |
JAKUBOWSKI, W | 1 |
CAMPOLATTARO, JP | 1 |
HAROLDSON, JH | 1 |
WELBORN, JF | 1 |
KANE, JP | 1 |
ANSELL, G | 1 |
ANSELL, A | 1 |
PERKINS, HM | 1 |
Berkun, Y | 1 |
Ben-Zvi, A | 1 |
Levy, Y | 1 |
Galili, D | 1 |
Shalit, M | 1 |
Lange, G | 1 |
Venter, EK | 1 |
Meyer, BJ | 1 |
Parker, JF | 1 |
Vats, A | 1 |
Bauer, G | 1 |
Amsler, E | 1 |
Flahault, A | 1 |
Mathelier-Fusade, P | 1 |
Aractingi, S | 1 |
Quhill, F | 1 |
Bowling, B | 1 |
Packard, RB | 1 |
Suzuki, J | 1 |
Nikko, H | 1 |
Kaiho, F | 1 |
Yamaguchi, K | 1 |
Wada, H | 1 |
Suzuki, M | 1 |
Acharya, D | 1 |
Kohase, H | 1 |
Umino, M | 1 |
Dance, D | 1 |
Basti, S | 1 |
Koch, DD | 1 |
Patil, B | 1 |
Agius-Fernandez, A | 1 |
Worstmann, T | 1 |
Ng, JM | 1 |
Villeneuve, V | 1 |
Kaufman, I | 1 |
Weeks, S | 1 |
Deschamps, A | 1 |
Komericki, P | 1 |
Arbab, E | 1 |
Grims, R | 1 |
Kränke, B | 1 |
Aberer, W | 1 |
Levy, J | 1 |
Lifshitz, T | 1 |
Noormalin, A | 1 |
Shahnaz, M | 1 |
Rosmilah, M | 1 |
Mujahid, SH | 1 |
Gendeh, BS | 1 |
Parkinson, J | 1 |
Tremblay, F | 1 |
Haugen, RN | 1 |
Brown, CW | 1 |
Gottlieb, SJ | 1 |
Falliers, CJ | 1 |
Fardon, DF | 1 |
Tamura, T | 1 |
Duff, HJ | 1 |
Roden, DM | 1 |
Marney, S | 1 |
Colley, DG | 1 |
Maffucci, R | 1 |
Primm, RK | 1 |
Oates, JA | 1 |
Woosley, RL | 1 |
Lederman, DA | 1 |
Freedman, PD | 1 |
Kerpel, SM | 1 |
Lumerman, H | 1 |
Metzner, HH | 1 |
Braun, G | 1 |
Wahl, G | 1 |
Sekiguchi, M | 1 |
Kamiura, M | 1 |
Iinuma, M | 1 |
Ito, K | 1 |
Baba, H | 1 |
Asakura, T | 1 |
Maeda, M | 1 |
Brubnjak-Jevtic, V | 1 |
Swanson, JG | 2 |
Barer, MR | 1 |
McAllen, MK | 1 |
Wildsmith, JA | 1 |
Gill, C | 1 |
Michaelides, PL | 1 |
Babajews, AV | 1 |
Ivanyi, L | 1 |
Srivastava, VK | 1 |
Nath, C | 1 |
Srivastava, M | 1 |
Pape, LA | 1 |
Dry, J | 1 |
Leynadier, F | 1 |
Chin, TM | 1 |
Fellner, MJ | 1 |
Mulvey, PM | 1 |
Jackson, D | 1 |
Chen, AH | 1 |
Bennett, CR | 1 |
Thakur, BK | 1 |
Murali, MR | 1 |
Dire, DJ | 1 |
Hogan, DE | 1 |
Hodgson, TA | 1 |
Shirlaw, PJ | 1 |
Challacombe, SJ | 1 |
Green, SM | 1 |
Whalen, JD | 1 |
Dufresne, RG | 1 |
Goswamy, R | 1 |
Prabhudesai, P | 1 |
Chaudhuri, A | 1 |
Mahashur, AA | 1 |
Vaidyanathan, S | 1 |
Krishnan, KR | 1 |
Soni, BM | 1 |
Fraser, MH | 1 |
Zanni, MP | 3 |
von Greyerz, S | 3 |
Schnyder, B | 3 |
Mauri-Hellweg, D | 1 |
Brander, C | 1 |
Kalbermatten, C | 1 |
Pichler, WJ | 3 |
Fader, DJ | 1 |
Johnson, TM | 1 |
Cuesta-Herranz, J | 1 |
de las Heras, M | 1 |
Fernández, M | 1 |
Lluch, M | 1 |
Figueredo, E | 1 |
Umpierrez, A | 1 |
Lahoz, C | 1 |
Gourrier, E | 1 |
Karoubi, P | 1 |
el Hanache, A | 1 |
Merbouche, S | 1 |
Mouchnino, G | 1 |
Leraillez, J | 1 |
Selcuk, E | 1 |
Ertürk, S | 1 |
Afrashi, A | 1 |
Meechan, J | 1 |
Wendland, T | 1 |
Bartfield, JM | 1 |
Jandreau, SW | 1 |
Raccio-Robak, N | 1 |
Ezsias, A | 2 |
Hari, Y | 1 |
Walters, G | 1 |
Georgiou, T | 1 |
Hayward, JM | 1 |
Ball, IA | 1 |
Bircher, AJ | 1 |
Surber, C | 1 |
Dilraj, A | 1 |
Cutts, FT | 1 |
Bennett, JV | 1 |
Coovadia, HM | 1 |
Lorette, G | 1 |
Kakuyama, M | 1 |
Toda, H | 1 |
Osawa, M | 1 |
Fukuda, K | 1 |
Zuberi, BF | 1 |
Shaikh, MR | 1 |
Jatoi, NU | 1 |
Shaikh, WM | 1 |
Rood, JP | 2 |
Scala, E | 1 |
Giani, M | 1 |
Pirrotta, L | 1 |
Guerra, EC | 1 |
Girardelli, CR | 1 |
De Pità, O | 1 |
Puddu, P | 1 |
Kalghatgi, S | 1 |
Campbell, JR | 1 |
Maestrello, CL | 1 |
Campbell, RL | 1 |
Simon, E | 1 |
Matee, M | 1 |
Browne, IM | 1 |
Birnbach, DJ | 1 |
Cetinkaya, F | 1 |
Brown, RS | 1 |
Paluvoi, S | 1 |
Choksi, S | 1 |
Burgess, CM | 1 |
Reece, ER | 1 |
Sabbah, A | 2 |
Hoffmann, H | 1 |
Maibach, HI | 1 |
Prout, E | 1 |
Luebke, NH | 1 |
Walker, JA | 1 |
Aldrete, JA | 4 |
Cass, N | 1 |
Dosseh, MB | 1 |
Dupiot, M | 1 |
Guèye, MS | 1 |
Goldberg, RT | 1 |
Wightman, MA | 1 |
Vaughan, RW | 1 |
Verrill, PJ | 1 |
Grimes, DA | 1 |
Cates, W | 1 |
Ravindranathan, N | 1 |
Poraszka, J | 1 |
Szeluga, J | 1 |
Stofer, AR | 1 |
Ulrich, L | 1 |
Steinsiepe, KF | 1 |
Egger, G | 1 |
Narang, R | 1 |
Dunoyer-Geindre, S | 1 |
Ludi, F | 1 |
Perez, T | 1 |
Terki, N | 1 |
Gumowski, PI | 1 |
Girard, JP | 1 |
Klein, CE | 1 |
Gall, H | 1 |
Kurashima, K | 1 |
Ogawa, H | 1 |
Namura, M | 1 |
Kanaya, N | 1 |
Oya, T | 1 |
Hayashi, M | 1 |
Fujimura, M | 1 |
Matsuda, T | 1 |
Ahmad, S | 1 |
Fisher, DA | 1 |
Grothe, DR | 1 |
Sunderland, T | 1 |
Vitiello, B | 1 |
Martinez, R | 1 |
Harris, P | 1 |
Le Sellin, J | 1 |
Drouet, M | 1 |
Bonneau, JC | 1 |
Dooms-Goossens, A | 1 |
de Alam, AG | 1 |
Degreef, H | 1 |
Kochuyt, A | 1 |
Dunn, JM | 1 |
Groth, PE | 1 |
DeSimone, A | 1 |
Tucker, LE | 1 |
Ruffles, SP | 1 |
Gayres, JG | 1 |
Levy, SM | 1 |
Baker, KA | 1 |
Chandler, MJ | 1 |
Grammer, LC | 1 |
Patterson, R | 1 |
Miyake, T | 1 |
Kawamori, J | 1 |
Yoshida, T | 1 |
Ivey, DF | 1 |
Müller, U | 1 |
Bircher, A | 1 |
Bischof, M | 1 |
Falace, DA | 1 |
Hill, JS | 1 |
Kennedy, KS | 1 |
Cave, RH | 1 |
Eyre, J | 1 |
Nally, FF | 1 |
Lehner, T | 1 |
Wetherall, JD | 1 |
Hackshaw, R | 1 |
Turner, KJ | 1 |
Sehhati, G | 1 |
Frey, R | 1 |
Mildner, R | 1 |
Smith, RB | 1 |
Everett, WG | 1 |
Shields, PW | 2 |
Divinyi, T | 1 |
Gyulavári, O | 1 |
Alföldy, G | 1 |
Harris, R | 1 |
Brown, LL | 1 |
Covino, BG | 1 |
Fink, BR | 1 |
Reinisch, J | 1 |
Myers, B | 1 |
Judit, BS | 1 |
Sandmire, HF | 1 |
Austin, SD | 1 |
Farber, HI | 1 |
Oelschläger, H | 1 |
Nieschulz, O | 1 |
Meyer, F | 1 |
Schulz, KH | 1 |
Finsterbush, A | 1 |
Stein, H | 1 |
Robin, GC | 1 |
Geller, R | 1 |
Cotev, S | 1 |
Woldorf, NM | 1 |
Pastore, PN | 1 |
Collan, Y | 1 |
Servo, C | 1 |
Winblad, I | 1 |
O'Higgins, JW | 1 |
Geddes, IC | 1 |
Waldman, HB | 1 |
Binkley, G | 1 |
Wellins, SL | 1 |
Terai, Y | 1 |
Tamagawa, K | 1 |
Kojima, M | 1 |
Gruszecka, M | 1 |
Kralisz, W | 1 |
Todd, DP | 1 |
Bartsch, R | 1 |
Graupner, K | 1 |
Walker, RT | 1 |
Jedrzejewska, A | 1 |
Lynas, RF | 1 |
Munsey, WF | 1 |
Kopp, WL | 1 |
Clinical Trials (12)
Trial Overview
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Efficacy and Safety of Prilocaine 2% and Lidocaine 5% Hyperbaric Against Spinal Anesthesia in Post Cystoscopy Procedure[NCT05834647] | Phase 4 | 45 participants (Anticipated) | Interventional | 2023-08-01 | Not yet recruiting | ||
Effects of Continuous Lidocaine Infusion Via Closed Chest Drainage Tube on Postoperative Analgesia for Patients Undergoing Thoracoscopic Partial Lung Resection: a Single-center Randomized Controlled Clinical Trial[NCT05901389] | 456 participants (Anticipated) | Interventional | 2023-06-30 | Not yet recruiting | |||
Efficacy of Postoperative Pain Control Between Transarticular VS Periartiucular Multimodal Drug Infiltration in Total Hip Arthroplasty: Double-blinded Randomized Control Trial[NCT05325671] | 120 participants (Anticipated) | Interventional | 2022-04-05 | Not yet recruiting | |||
The Comparison Between Dexamethasone and Morphine as an Adjuvant to Epidural Bupivacaine for Post-operative Analgesia in Lower Extremity Surgery[NCT03051022] | 64 participants (Actual) | Interventional | 2016-05-01 | Completed | |||
Comparative Study of the Anaesthetic Efficacy of 4% Articaine Versus 2% Mepivacaine in Mandibular Third Molar Germectomy Using Different Anaesthetic Techniques: a Split-mouth Clinical Trial[NCT04465149] | 50 participants (Actual) | Interventional | 2018-06-30 | Completed | |||
Clinical Evaluation of Arrhythmia Mapping With a Globe-Shaped, High-Density, Multi-Electrode Mapping Catheter[NCT05373862] | 40 participants (Actual) | Interventional | 2022-07-29 | Completed | |||
Clinical Evaluation of Arrhythmia Mapping With the Multi-Electrode OPTRELL™ Mapping Catheter[NCT04983797] | 31 participants (Actual) | Interventional | 2021-08-25 | Completed | |||
Clinical Evaluation of Intracardiac Ultrasound With the NUVISION NAV Ultrasound Catheter[NCT05970120] | 30 participants (Anticipated) | Interventional | 2023-09-05 | Recruiting | |||
Maternal-Fetal Monitoring of Patients With Rheumatic Heart Disease During Dental Procedure Under Local Anesthesia[NCT00482573] | Phase 1 | 31 participants (Actual) | Interventional | 2004-04-30 | Completed | ||
Antipruritic Effect of Topical Ketamine, Amitriptyline, and Lidocaine[NCT03096444] | Phase 2 | 13 participants (Actual) | Interventional | 2017-05-23 | Terminated (stopped due to Efficacy was not seen after interim analysis) | ||
Assessing the Effect of Paracervical Block Volume on Pain Control for Dilation and Curettage: a Randomized Controlled Trial[NCT03636451] | Phase 3 | 114 participants (Actual) | Interventional | 2018-10-29 | Completed | ||
An Evaluation of the Paracervical Block for Pain Control in First Trimester Surgical Abortion[NCT01094366] | Phase 4 | 121 participants (Actual) | Interventional | 2010-04-30 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Trial Outcomes
Number of Participants With Non-serious Adverse Events Within 7 Days of Index Procedure Associated With the Use of the OPTRELL Catheter
Number of participants with non-serious adverse events within 7 days of index procedure associated with the use of the OPTRELL catheter were reported. An AE is any untoward medical occurrence in a participant participating in a clinical study that does not necessarily have a causal relationship with the pharmaceutical/biological agent under study. (NCT04983797)
Timeframe: Up to 7 days of index procedure at Day 0
Intervention | Participants (Count of Participants) |
---|---|
OPTRELL Mapping Catheter | 0 |
Number of Participants With Pre-ablation Mapping and Clinically Indicated Mapping Performed With the OPTRELL Catheter Without Resort to Other Mapping Catheters
Number of participants with pre-ablation mapping and clinically indicated mapping performed with the OPTRELL catheter without resort to other mapping catheters were reported. (NCT04983797)
Timeframe: Up to 72 days
Intervention | Participants (Count of Participants) |
---|---|
OPTRELL Mapping Catheter | 31 |
Number of Participants With SAEs Within 7 Days of Index Procedure
Number of participants with SAEs within 7 days of index procedure were reported. An AE is any untoward medical occurrence in a participant whether or not related to the investigational device. SAE is any AE that results in: death, persistent or significant disability/incapacity, requires inpatient hospitalization or prolongation of existing hospitalization, is life-threatening experience, is a congenital anomaly/birth defect and may jeopardize participant and/or may require medical or surgical intervention to prevent one of the outcomes listed above. (NCT04983797)
Timeframe: Up to 7 days of index procedure at Day 0
Intervention | Participants (Count of Participants) |
---|---|
OPTRELL Mapping Catheter | 3 |
Number of Participants With Serious Adverse Events (SAEs) Within 7 Days of Index Procedure Related to the OPTRELL Catheter
Number of participants with SAEs within 7 days of index procedure related to the OPTRELL catheter were reported. An adverse event (AE) is any untoward medical occurrence in a participant whether or not related to the investigational device. SAE is any AE that results in: death, persistent or significant disability/incapacity, requires inpatient hospitalization or prolongation of existing hospitalization, is life-threatening experience, is a congenital anomaly/birth defect and may jeopardize participant and/or may require medical or surgical intervention to prevent one of the outcomes listed above. (NCT04983797)
Timeframe: Up to 7 days of index procedure at Day 0
Intervention | Participants (Count of Participants) |
---|---|
OPTRELL Mapping Catheter | 0 |
Number of Responders for Physician Assessment for Ability to Characterize the Tissue
Number of responders for physician assessment for ability to characterize the tissue were reported. A post-procedure survey of 11 questions, each with individual sub-questions were asked. Each question/sub-question was answered by the physician using a Likert scale of 1 to 7 (1=poor and 7=excellent). Responders refers to participants with physician assessment for ability to characterize the tissue. (NCT04983797)
Timeframe: Up to 72 days
Intervention | Participants (Count of Participants) | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Compared to the PENTARAY catheter?: Score 1 | Compared to the PENTARAY catheter?: Score 2 | Compared to the PENTARAY catheter?: Score 3 | Compared to the PENTARAY catheter?: Score 4 | Compared to the PENTARAY catheter?: Score 5 | Compared to the PENTARAY catheter?: Score 6 | Compared to the PENTARAY catheter?: Score 7 | Compared to other competitive multielectrode catheters?: Score 1 | Compared to other competitive multielectrode catheters?: Score 2 | Compared to other competitive multielectrode catheters?: Score 3 | Compared to other competitive multielectrode catheters?: Score 4 | Compared to other competitive multielectrode catheters?: Score 5 | Compared to other competitive multielectrode catheters?: Score 6 | Compared to other competitive multielectrode catheters?: Score 7 | |
OPTRELL Mapping Catheter | 0 | 0 | 0 | 0 | 0 | 16 | 15 | 0 | 0 | 0 | 0 | 0 | 25 | 0 |
Number of Responders for Physician Assessment for Arrhythmogenicity
Number of responders with physician assessment for arrhythmogenicity were reported. A post-procedure survey of 11 questions, each with individual sub-questions were asked. Each question/sub-question was answered by the physician using a Likert scale of 1 to 7 (1=poor and 7=excellent). Responders refers to participants with physician assessment for arrhythmogenicity. (NCT04983797)
Timeframe: Up to 72 days
Intervention | Participants (Count of Participants) | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Compared to the PENTARAY catheter?: Score 1 | Compared to the PENTARAY catheter?: Score 2 | Compared to the PENTARAY catheter?: Score 3 | Compared to the PENTARAY catheter?: Score 4 | Compared to the PENTARAY catheter?: Score 5 | Compared to the PENTARAY catheter?: Score 6 | Compared to the PENTARAY catheter?: Score 7 | Compared to other competitive multielectrode catheters?: Score 1 | Compared to other competitive multielectrode catheters?: Score 2 | Compared to other competitive multielectrode catheters?: Score 3 | Compared to other competitive multielectrode catheters?: Score 4 | Compared to other competitive multielectrode catheters?: Score 5 | Compared to other competitive multielectrode catheters?: Score 6 | Compared to other competitive multielectrode catheters?: Score 7 | |
OPTRELL Mapping Catheter | 0 | 0 | 0 | 2 | 5 | 10 | 14 | 0 | 0 | 0 | 0 | 5 | 19 | 1 |
Number of Responders for Physician Assessment for Catheter Design in OPTRELL Catheter for Mapping
Number of responders for physician assessment for catheter design were reported. A post-procedure survey of 11 questions, each with individual sub-questions were asked. Each question/sub-question was answered by the physician using a Likert scale of 1 to 7 (1=poor and 7=excellent). Responders refers to participants with physician assessment for catheter design in OPTRELL catheter for mapping. (NCT04983797)
Timeframe: Up to 72 days
Intervention | Participants (Count of Participants) | ||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ability to achieve electrode contact with cardiac tissue: Score 1 | Ability to achieve electrode contact with cardiac tissue: Score 2 | Ability to achieve electrode contact with cardiac tissue: Score 3 | Ability to achieve electrode contact with cardiac tissue: Score 4 | Ability to achieve electrode contact with cardiac tissue: Score 5 | Ability to achieve electrode contact with cardiac tissue: Score 6 | Ability to achieve electrode contact with cardiac tissue: Score 7 | Electrodes spacing: Score 1 | Electrodes spacing: Score 2 | Electrodes spacing: Score 3 | Electrodes spacing: Score 4 | Electrodes spacing: Score 5 | Electrodes spacing: Score 6 | Electrodes spacing: Score 7 | Electrode array coverage: Score 1 | Electrode array coverage: Score 2 | Electrode array coverage: Score 3 | Electrode array coverage: Score 4 | Electrode array coverage: Score 5 | Electrode array coverage: Score 6 | Electrode array coverage: Score 7 | |
OPTRELL Mapping Catheter | 0 | 1 | 0 | 2 | 2 | 18 | 8 | 0 | 1 | 0 | 0 | 0 | 13 | 17 | 0 | 1 | 0 | 0 | 0 | 9 | 21 |
Number of Responders for Physician Assessment for Catheter Visualization
Number of responders for physician assessment for catheter visualization were reported. A post-procedure survey of 11 questions, each with individual sub-questions were asked. Each question/sub-question was answered by the physician using a Likert scale of 1 to 7 (1=poor and 7=excellent). Responders refers to participants with physician assessment for catheter visualization. (NCT04983797)
Timeframe: Up to 72 days
Intervention | Participants (Count of Participants) | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Visualization under fluoroscopy: Score 1 | Visualization under fluoroscopy: Score 2 | Visualization under fluoroscopy: Score 3 | Visualization under fluoroscopy: Score 4 | Visualization under fluoroscopy: Score 5 | Visualization under fluoroscopy: Score 6 | Visualization under fluoroscopy: Score 7 | Visualization in CARTO 3: Score 1 | Visualization in CARTO 3: Score 2 | Visualization in CARTO 3: Score 3 | Visualization in CARTO 3: Score 4 | Visualization in CARTO 3: Score 5 | Visualization in CARTO 3: Score 6 | Visualization in CARTO 3: Score 7 | |
OPTRELL Mapping Catheter | 0 | 0 | 0 | 0 | 7 | 9 | 15 | 0 | 0 | 0 | 0 | 3 | 10 | 18 |
Number of Responders for Physician Assessment for Catheters Interactions
Number of responders for physician assessment for catheters interactions were reported. A post-procedure survey of 11 questions, each with individual sub-questions were asked. Each question/sub-question was answered by the physician using a Likert scale of 1 to 7 (1=poor and 7=excellent). Responders refers to participants with physician assessment for catheters interactions. (NCT04983797)
Timeframe: Up to 72 days
Intervention | Participants (Count of Participants) | ||||||||||||||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
With CARTO 3 System: Score 1 | With CARTO 3 System: Score 2 | With CARTO 3 System: Score 3 | With CARTO 3 System: Score 4 | With CARTO 3 System: Score 5 | With CARTO 3 System: Score 6 | With CARTO 3 System: Score 7 | EP Lab recording equipment: Score 1 | EP Lab recording equipment: Score 2 | EP Lab recording equipment: Score 3 | EP Lab recording equipment: Score 4 | EP Lab recording equipment: Score 5 | EP Lab recording equipment: Score 6 | EP Lab recording equipment: Score 7 | Pacing equipment: Score 1 | Pacing equipment: Score 2 | Pacing equipment: Score 3 | Pacing equipment: Score 4 | Pacing equipment: Score 5 | Pacing equipment: Score 6 | Pacing equipment: Score 7 | Introducer tool on catheter: Score 1 | Introducer tool on catheter: Score 2 | Introducer tool on catheter: Score 3 | Introducer tool on catheter: Score 4 | Introducer tool on catheter: Score 5 | Introducer tool on catheter: Score 6 | Introducer tool on catheter: Score 7 | Sheath: Score 1 | Sheath: Score 2 | Sheath: Score 3 | Sheath: Score 4 | Sheath: Score 5 | Sheath: Score 6 | Sheath: Score 7 | Irrigation bag and tubing: Score 1 | Irrigation bag and tubing: Score 2 | Irrigation bag and tubing: Score 3 | Irrigation bag and tubing: Score 4 | Irrigation bag and tubing: Score 5 | Irrigation bag and tubing: Score 6 | Irrigation bag and tubing: Score 7 | ICD or other implantable devices: Score 1 | ICD or other implantable devices: Score 2 | ICD or other implantable devices: Score 3 | ICD or other implantable devices: Score 4 | ICD or other implantable devices: Score 5 | ICD or other implantable devices: Score 6 | ICD or other implantable devices: Score 7 | |
OPTRELL Mapping Catheter | 0 | 0 | 0 | 0 | 4 | 12 | 15 | 0 | 0 | 0 | 1 | 8 | 12 | 10 | 0 | 0 | 0 | 0 | 4 | 3 | 7 | 0 | 0 | 0 | 3 | 6 | 14 | 8 | 0 | 0 | 0 | 3 | 6 | 14 | 8 | 0 | 0 | 0 | 0 | 5 | 15 | 11 | 0 | 0 | 0 | 1 | 2 | 2 | 3 |
Number of Responders for Physician Assessment for Design and Coverage for Confirming PVI
Number of responders for physician assessment for design and coverage for confirming PVI were reported. A post-procedure survey of 11 questions, each with individual sub-questions were asked. Each question/sub-question was answered by the physician using a Likert scale of 1 to 7 (1=poor and 7=excellent). Responders refers to participants with physician assessment for design and coverage for confirming PVI. (NCT04983797)
Timeframe: Up to 72 days
Intervention | Participants (Count of Participants) | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Compared to the PENTARAY catheter?: Score 1 | Compared to the PENTARAY catheter?: Score 2 | Compared to the PENTARAY catheter?: Score 3 | Compared to the PENTARAY catheter?: Score 4 | Compared to the PENTARAY catheter?: Score 5 | Compared to the PENTARAY catheter?: Score 6 | Compared to the PENTARAY catheter?: Score 7 | Compared to other competitive multielectrode catheters?: Score 1 | Compared to other competitive multielectrode catheters?: Score 2 | Compared to other competitive multielectrode catheters?: Score 3 | Compared to other competitive multielectrode catheters?: Score 4 | Compared to other competitive multielectrode catheters?: Score 5 | Compared to other competitive multielectrode catheters?: Score 6 | Compared to other competitive multielectrode catheters?: Score 7 | |
OPTRELL Mapping Catheter | 0 | 0 | 0 | 3 | 2 | 7 | 9 | 0 | 0 | 0 | 4 | 0 | 13 | 4 |
Number of Responders for Physician Assessment for Maneuverability & Handling
Number of responders for physician assessment for maneuverability & handling were reported. A post-procedure survey of 11 questions, each with individual sub-questions were asked. Each question/sub-question was answered by the physician using a Likert scale of 1 to 7 (1=poor and 7=excellent). Responders refers to participants with physician assessment for maneuverability & handling. (NCT04983797)
Timeframe: Up to 72 days
Intervention | Participants (Count of Participants) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ability to Deploy (Left Atrium): Score 1 | Ability to Deploy (Left Atrium): Score 2 | Ability to Deploy (Left Atrium): Score 3 | Ability to Deploy (Left Atrium): Score 4 | Ability to Deploy (Left Atrium): Score 5 | Ability to Deploy (Left Atrium): Score 6 | Ability to Deploy (Left Atrium): Score 7 | Ability to Deploy (Right Atrium): Score 1 | Ability to Deploy (Right Atrium): Score 2 | Ability to Deploy (Right Atrium): Score 3 | Ability to Deploy (Right Atrium): Score 4 | Ability to Deploy (Right Atrium): Score 5 | Ability to Deploy (Right Atrium): Score 6 | Ability to Deploy (Right Atrium): Score 7 | Ability to Deploy (Left Ventricle): Score 1 | Ability to Deploy (Left Ventricle): Score 2 | Ability to Deploy (Left Ventricle): Score 3 | Ability to Deploy (Left Ventricle): Score 4 | Ability to Deploy (Left Ventricle): Score 5 | Ability to Deploy (Left Ventricle): Score 6 | Ability to Deploy (Left Ventricle): Score 7 | Ability to Deploy (Right Ventricle): Score 1 | Ability to Deploy (Right Ventricle): Score 2 | Ability to Deploy (Right Ventricle): Score 3 | Ability to Deploy (Right Ventricle): Score 4 | Ability to Deploy (Right Ventricle): Score 5 | Ability to Deploy (Right Ventricle): Score 6 | Ability to Deploy (Right Ventricle): Score 7 | Ability to Maneuver (Left Atrium): Score 1 | Ability to Maneuver (Left Atrium): Score 2 | Ability to Maneuver (Left Atrium): Score 3 | Ability to Maneuver (Left Atrium): Score 4 | Ability to Maneuver (Left Atrium): Score 5 | Ability to Maneuver (Left Atrium): Score 6 | Ability to Maneuver (Left Atrium): Score 7 | Ability to Maneuver (Right Atrium): Score 1 | Ability to Maneuver (Right Atrium): Score 2 | Ability to Maneuver (Right Atrium): Score 3 | Ability to Maneuver (Right Atrium): Score 4 | Ability to Maneuver (Right Atrium): Score 5 | Ability to Maneuver (Right Atrium): Score 6 | Ability to Maneuver (Right Atrium): Score 7 | Ability to Maneuver (Left Ventricle): Score 1 | Ability to Maneuver (Left Ventricle): Score 2 | Ability to Maneuver (Left Ventricle): Score 3 | Ability to Maneuver (Left Ventricle): Score 4 | Ability to Maneuver (Left Ventricle): Score 5 | Ability to Maneuver (Left Ventricle): Score 6 | Ability to Maneuver (Left Ventricle): Score 7 | Ability to Maneuver (Right Ventricle): Score 1 | Ability to Maneuver (Right Ventricle): Score 2 | Ability to Maneuver (Right Ventricle): Score 3 | Ability to Maneuver (Right Ventricle): Score 4 | Ability to Maneuver (Right Ventricles): Score 5 | Ability to Maneuver (Right Ventricle): Score 6 | Ability to Maneuver (Right Ventricle): Score 7 | Ability to Reach Areas (Left Atrium): Score 1 | Ability to Reach Areas (Left Atrium): Score 2 | Ability to Reach Areas (Left Atrium): Score 3 | Ability to Reach Areas (Left Atrium): Score 4 | Ability to Reach Areas (Left Atrium): Score 5 | Ability to Reach Areas (Left Atrium): Score 6 | Ability to Reach Areas (Left Atrium): Score 7 | Ability to Reach Areas (Right Atrium): Score 1 | Ability to Reach Areas (Right Atrium): Score 2 | Ability to Reach Areas (Right Atrium): Score 3 | Ability to Reach Areas (Right Atrium): Score 4 | Ability to Reach Areas (Right Atrium): Score 5 | Ability to Reach Areas (Right Atrium): Score 6 | Ability to Reach Areas (Right Atrium): Score 7 | Ability to Reach Areas (Left Ventricle): Score 1 | Ability to Reach Areas (Left Ventricle): Score 2 | Ability to Reach Areas (Left Ventricle): Score 3 | Ability to Reach Areas (Left Ventricle): Score 4 | Ability to Reach Areas (Left Ventricle): Score 5 | Ability to Reach Areas (Left Ventricle): Score 6 | Ability to Reach Areas (Left Ventricle): Score 7 | Ability to Reach Areas (Right Ventricle): Score 1 | Ability to Reach Areas (Right Ventricle): Score 2 | Ability to Reach Areas (Right Ventricle): Score 3 | Ability to Reach Areas (Right Ventricle): Score 4 | Ability to Reach Areas (Right Ventricle): Score 5 | Ability to Reach Areas (Right Ventricle): Score 6 | Ability to Reach Areas (Right Ventricle): Score 7 | Ability to Withdraw (Left Atrium): Score 1 | Ability to Withdraw (Left Atrium): Score 2 | Ability to Withdraw (Left Atrium): Score 3 | Ability to Withdraw (Left Atrium): Score 4 | Ability to Withdraw (Left Atrium): Score 5 | Ability to Withdraw (Left Atrium): Score 6 | Ability to Withdraw (Left Atrium): Score 7 | Ability to Withdraw (Right Atrium): Score 1 | Ability to Withdraw (Right Atrium): Score 2 | Ability to Withdraw (Right Atrium): Score 3 | Ability to Withdraw (Right Atrium): Score 4 | Ability to Withdraw (Right Atrium): Score 5 | Ability to Withdraw (Right Atrium): Score 6 | Ability to Withdraw (Right Atrium): Score 7 | Ability to Withdraw (Left Ventricle): Score 1 | Ability to Withdraw (Left Ventricle): Score 2 | Ability to Withdraw (Left Ventricle): Score 3 | Ability to Withdraw (Left Ventricle): Score 4 | Ability to Withdraw (Left Ventricle): Score 5 | Ability to Withdraw (Left Ventricle): Score 6 | Ability to Withdraw (Left Ventricle): Score 7 | Ability to Withdraw (Right Ventricle): Score 1 | Ability to Withdraw (Right Ventricle): Score 2 | Ability to Withdraw (Right Ventricle): Score 3 | Ability to Withdraw (Right Ventricle): Score 4 | Ability to Withdraw (Right Ventricle): Score 5 | Ability to Withdraw (Right Ventricle): Score 6 | Ability to Withdraw (Right Ventricle): Score 7 | Insertion/ Withdrawal from Introducer Sheath: Score 1 | Insertion/ Withdrawal from Introducer Sheath: Score 2 | Insertion/ Withdrawal from Introducer Sheath: Score 3 | Insertion/ Withdrawal from Introducer Sheath: Score 4 | Insertion/ Withdrawal from Introducer Sheath: Score 5 | Insertion/ Withdrawal from Introducer Sheath: Score 6 | Insertion/ Withdrawal from Introducer Sheath: Score 7 | Learning Curve: Score 1 | Learning Curve: Score 2 | Learning Curve: Score 3 | Learning Curve: Score 4 | Learning Curve: Score 5 | Learning Curve: Score 6 | Learning Curve: Score 7 | |
OPTRELL Mapping Catheter | 0 | 0 | 0 | 0 | 0 | 6 | 17 | 0 | 0 | 0 | 0 | 0 | 3 | 3 | 0 | 0 | 0 | 3 | 1 | 5 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7 | 7 | 9 | 0 | 0 | 0 | 0 | 1 | 1 | 4 | 0 | 0 | 0 | 5 | 0 | 4 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 3 | 12 | 6 | 0 | 0 | 0 | 0 | 2 | 1 | 3 | 0 | 0 | 1 | 3 | 2 | 3 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8 | 15 | 0 | 0 | 0 | 0 | 0 | 4 | 2 | 0 | 0 | 0 | 2 | 2 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 2 | 9 | 9 | 10 | 0 | 0 | 0 | 4 | 4 | 18 | 5 |
Number of Responders for Physician Assessment for Pacing
Number of responders for physician assessment for pacing (local pacing capture) were reported. A post-procedure survey of 11 questions, each with individual sub-questions were asked. Each question/sub-question was answered by the physician using a Likert scale of 1 to 7 (1=poor and 7=excellent). Responders refers to participants with physician assessment for pacing. (NCT04983797)
Timeframe: Up to 72 days
Intervention | Participants (Count of Participants) | ||||||
---|---|---|---|---|---|---|---|
Local pacing capture: Score 1 | Local pacing capture: Score 2 | Local pacing capture: Score 3 | Local pacing capture: Score 4 | Local pacing capture: Score 5 | Local pacing capture: Score 6 | Local pacing capture: Score 7 | |
OPTRELL Mapping Catheter | 0 | 0 | 1 | 1 | 2 | 2 | 3 |
Number of Responders for Physician Assessment for Signal Collection and Quality
Number of responders for physician assessment for signal collection and quality were reported. A post-procedure survey of 11 questions, each with individual sub-questions were asked. Each question/sub-question was answered by the physician using a Likert scale of 1 to 7 (1=poor and 7=excellent). Responders refers to participants with physician assessment for signal collection and quality (NCT04983797)
Timeframe: Up to 72 days
Intervention | Participants (Count of Participants) | |||||||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
UNIPOLAR signals in Atrium: Score 1 | UNIPOLAR signals in Atrium: Score 2 | UNIPOLAR signals in Atrium: Score 3 | UNIPOLAR signals in Atrium: Score 4 | UNIPOLAR signals in Atrium: Score 5 | UNIPOLAR signals in Atrium: Score 6 | UNIPOLAR signals in Atrium: Score 7 | UNIPOLAR signals in Ventricle: Score 1 | UNIPOLAR signals in Ventricle: Score 2 | UNIPOLAR signals in Ventricle: Score 3 | UNIPOLAR signals in Ventricle: Score 4 | UNIPOLAR signals in Ventricle: Score 5 | UNIPOLAR signals in Ventricle: Score 6 | UNIPOLAR signals in Ventricle: Score 7 | UNIPOLAR noise encountered: Score 1 | UNIPOLAR noise encountered: Score 2 | UNIPOLAR noise encountered: Score 3 | UNIPOLAR noise encountered: Score 4 | UNIPOLAR noise encountered: Score 5 | UNIPOLAR noise encountered: Score 6 | UNIPOLAR noise encountered: Score 7 | BIPOLAR signals in Atrium: Score 1 | BIPOLAR signals in Atrium: Score 2 | BIPOLAR signals in Atrium: Score 3 | BIPOLAR signals in Atrium: Score 4 | BIPOLAR signals in Atrium: Score 5 | BIPOLAR signals in Atrium: Score 6 | BIPOLAR signals in Atrium: Score 7 | BIPOLAR signals in Ventricle: Score 1 | BIPOLAR signals in Ventricle: Score 2 | BIPOLAR signals in Ventricle: Score 3 | BIPOLAR signals in Ventricle: Score 4 | BIPOLAR signals in Ventricle: Score 5 | BIPOLAR signals in Ventricle: Score 6 | BIPOLAR signals in Ventricle: Score 7 | BIPOLAR noise encountered: Score 1 | BIPOLAR noise encountered: Score 2 | BIPOLAR noise encountered: Score 3 | BIPOLAR noise encountered: Score 4 | BIPOLAR noise encountered: Score 5 | BIPOLAR noise encountered: Score 6 | BIPOLAR noise encountered: Score 7 | |
OPTRELL Mapping Catheter | 0 | 0 | 0 | 0 | 1 | 4 | 2 | 0 | 0 | 0 | 1 | 3 | 4 | 0 | 0 | 0 | 0 | 1 | 4 | 7 | 4 | 0 | 0 | 0 | 0 | 0 | 7 | 16 | 0 | 0 | 0 | 0 | 1 | 7 | 1 | 0 | 0 | 0 | 1 | 3 | 12 | 15 |
Number of Responders for Physician Assessment for Workflow
Number of responders for physician assessment for workflow were reported. A post-procedure survey of 11 questions, each with individual sub-questions were asked. Each question/sub-question was answered by the physician using a Likert scale of 1 to 7 (1=poor and 7=excellent). Responders refers to participants with physician assessment for workflow. (NCT04983797)
Timeframe: Up to 72 days
Intervention | Participants (Count of Participants) | |||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ability to reduce fluoroscopy: Score 1 | Ability to reduce fluoroscopy: Score 2 | Ability to reduce fluoroscopy: Score 3 | Ability to reduce fluoroscopy: Score 4 | Ability to reduce fluoroscopy: Score 5 | Ability to reduce fluoroscopy: Score 6 | Ability to reduce fluoroscopy: Score 7 | Time for pre-procedure mapping: Score 1 | Time for pre-procedure mapping: Score 2 | Time for pre-procedure mapping: Score 3 | Time for pre-procedure mapping: Score 4 | Time for pre-procedure mapping: Score 5 | Time for pre-procedure mapping: Score 6 | Time for pre-procedure mapping: Score 7 | Time for post-procedure mapping after standard of care ablation: Score 1 | Time for post-procedure mapping after standard of care ablation: Score 2 | Time for post-procedure mapping after standard of care ablation: Score 3 | Time for post-procedure mapping after standard of care ablation: Score 4 | Time for post-procedure mapping after standard of care ablation: Score 5 | Time for post-procedure mapping after standard of care ablation: Score 6 | Time for post-procedure mapping after standard of care ablation: Score 7 | Ability to identify targets: Score 1 | Ability to identify targets: Score 2 | Ability to identify targets: Score 3 | Ability to identify targets: Score 4 | Ability to identify targets: Score 5 | Ability to identify targets: Score 6 | Ability to identify targets: Score 7 | |
OPTRELL Mapping Catheter | 0 | 0 | 0 | 10 | 6 | 10 | 5 | 0 | 0 | 0 | 8 | 4 | 10 | 9 | 0 | 0 | 0 | 2 | 4 | 9 | 9 | 0 | 0 | 0 | 1 | 0 | 13 | 14 |
Peak Itch Intensity Between the Vehicle and Active Treatments (Individual and KeAmLi-combo).
"Peak itch intensity between the vehicle and 4 other active treatments (individual ketamine, amitriptyline, or lidocaine, and KeAmLi-combo). Itch intensity was measured on a 100mm scale visual analog scale for 10 minutes. 0 was weighted with no itch and 100 was weighted with most itch imaginable." (NCT03096444)
Timeframe: 10 minutes
Intervention | Intensity score (Mean) |
---|---|
Topical KeAmLi Combo | 62.7 |
Topical Ketamine | 63.1 |
Topical Amitriptyline | 69.2 |
Topical Lidocaine | 65.8 |
Topical Vehicle | 61.9 |
Mechanical Thresholds (Mechanical Detection and Pain).
Assess mechanical detection and pain thresholds using von Frey filaments stimulators (measured in force mN) to calculate the final threshold as the geometric mean of five series of ascending and descending stimuli. (NCT03096444)
Timeframe: 5 minutes
Intervention | mN (Mean) | |
---|---|---|
Mechanical Detection Threshold | Mechanical Pain Threshold | |
Topical Amitriptyline | 3.573423965 | 152.4768146 |
Topical KeAmLi Combo | 3.519376956 | 152.3293608 |
Topical Ketamine | 3.464204768 | 135.9 |
Topical Lidocaine | 3.546037659 | 126.9 |
Topical Vehicle | 3.525692637 | 148.7138273 |
Thermal Threshold Detection (Warmth and Heat Pain)
Two standardized quantitative sensory tests are performed to measure warmth detection threshold (assesses the threshold of which warmth sensation is first detected) and heat pain threshold (assesses the threshold at which heat pain sensation is first detected). Measured in change in celsius. (NCT03096444)
Timeframe: 3 minutes
Intervention | Degrees celsius (Mean) | |
---|---|---|
Warm Detection Threshold | Heat Pain Threshold | |
Topical Amitriptyline | 33.9 | 40.0 |
Topical KeAmLi Combo | 33.6 | 39.8 |
Topical Ketamine | 34.0 | 40.0 |
Topical Lidocaine | 33.7 | 39.4 |
Topical Vehicle | 33.8 | 39.7 |
Overall Pain
Distance (mm) from the left of the 100-mm Visual Analog Scale (VAS) (reflecting magnitude of pain) recorded after the procedure reflecting the overall pain felt during the procedure. Pain will be assessed using a 100 mm visual analogue scale with the anchors 0 = none, 100 mm = worst imaginable. (NCT03636451)
Timeframe: Once 10 minutes after the procedure on the day of recruitment, approximately one minute.
Intervention | units on a scale (Median) |
---|---|
20cc 1% Lidocaine With 2 Units of Vasopressin Paracervical Block | 57 |
40cc Buffered 0.5% Lidocaine With 2 Units of Vasopressin Paracervical Block | 56 |
Pain 10 Minutes Post Procedure
Distance (mm) from the left of the 100-mm Visual Analog Scale (VAS) (reflecting magnitude of pain) recorded 10 minutes after the completion of the procedure. Pain will be assessed using a 100 mm visual analogue scale with the anchors 0 = none, 100 mm = worst imaginable. (NCT03636451)
Timeframe: Once 10 minutes after the procedure on the day of recruitment, approximately one minute.
Intervention | units on a scale (Median) |
---|---|
20cc 1% Lidocaine With 2 Units of Vasopressin Paracervical Block | 26 |
40cc Buffered 0.5% Lidocaine With 2 Units of Vasopressin Paracervical Block | 11 |
Pain With Cervical Dilation
Distance (mm) from the left of the 100-mm Visual Analog Scale (VAS) (reflecting magnitude of pain) recorded at time of cervical dilation. Pain will be assessed using a 100 mm visual analogue scale with the anchors 0 = none, 100 mm = worst imaginable. (NCT03636451)
Timeframe: Once during the procedure on the day of recruitment, approximately one minute. During procedure at time of cervical dilation.
Intervention | units on a scale (Median) |
---|---|
20cc 1% Lidocaine With 2 Units of Vasopressin Paracervical Block | 52 |
40cc Buffered 0.5% Lidocaine With 2 Units of Vasopressin Paracervical Block | 45 |
Pain With Uterine Aspiration
Distance (mm) from the left of the 100-mm Visual Analog Scale (VAS) (reflecting magnitude of pain) recorded immediately after uterine aspiration. Pain will be assessed using a 100 mm visual analogue scale with the anchors 0 = none, 100 mm = worst imaginable. (NCT03636451)
Timeframe: Once during the procedure on the day of recruitment, approximately 1 minute. During procedure immediately after uterine aspiration.
Intervention | units on a scale (Median) |
---|---|
20cc 1% Lidocaine With 2 Units of Vasopressin Paracervical Block | 46 |
40cc Buffered 0.5% Lidocaine With 2 Units of Vasopressin Paracervical Block | 58 |
Reviews
12 reviews available for lidocaine and Drug Hypersensitivity
Article | Year |
---|---|
Lidocaine: A Local Anesthetic, Its Adverse Effects and Management.
Topics: Anesthesia, Local; Anesthetics, Local; Drug Hypersensitivity; Drug-Related Side Effects and Adverse | 2021 |
True Allergy to Amide Local Anesthetics: A Review and Case Presentation.
Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Contraindications, Drug; Diphenhydramine; Drug Hypers | 2018 |
Local anesthetics: review of pharmacological considerations.
Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane | 2012 |
Local anesthetics: review of pharmacological considerations.
Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane | 2012 |
Local anesthetics: review of pharmacological considerations.
Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane | 2012 |
Local anesthetics: review of pharmacological considerations.
Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane | 2012 |
Local anesthetics: review of pharmacological considerations.
Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane | 2012 |
Local anesthetics: review of pharmacological considerations.
Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane | 2012 |
Local anesthetics: review of pharmacological considerations.
Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane | 2012 |
Local anesthetics: review of pharmacological considerations.
Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane | 2012 |
Local anesthetics: review of pharmacological considerations.
Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane | 2012 |
Local anesthetics: review of pharmacological considerations.
Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane | 2012 |
Local anesthetics: review of pharmacological considerations.
Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane | 2012 |
Local anesthetics: review of pharmacological considerations.
Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane | 2012 |
Local anesthetics: review of pharmacological considerations.
Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane | 2012 |
Local anesthetics: review of pharmacological considerations.
Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane | 2012 |
Local anesthetics: review of pharmacological considerations.
Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane | 2012 |
Local anesthetics: review of pharmacological considerations.
Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane | 2012 |
Local anesthetics: review of pharmacological considerations.
Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane | 2012 |
Local anesthetics: review of pharmacological considerations.
Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane | 2012 |
Local anesthetics: review of pharmacological considerations.
Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane | 2012 |
Local anesthetics: review of pharmacological considerations.
Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane | 2012 |
Local anesthetics: review of pharmacological considerations.
Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane | 2012 |
Local anesthetics: review of pharmacological considerations.
Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane | 2012 |
Local anesthetics: review of pharmacological considerations.
Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane | 2012 |
Local anesthetics: review of pharmacological considerations.
Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane | 2012 |
Local anesthetics: review of pharmacological considerations.
Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane | 2012 |
Local anesthesia: advances in agents and techniques.
Topics: Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Carticaine; Chemistry, Pharm | 2002 |
Toxicity of local anaesthetics.
Topics: Anesthetics, Local; Animals; Bupivacaine; Cardiovascular System; Cocaine; Drug Hypersensitivity; Eti | 2003 |
Toxicity of local anaesthetics.
Topics: Anesthetics, Local; Animals; Bupivacaine; Cardiovascular System; Cocaine; Drug Hypersensitivity; Eti | 2003 |
Toxicity of local anaesthetics.
Topics: Anesthetics, Local; Animals; Bupivacaine; Cardiovascular System; Cocaine; Drug Hypersensitivity; Eti | 2003 |
Toxicity of local anaesthetics.
Topics: Anesthetics, Local; Animals; Bupivacaine; Cardiovascular System; Cocaine; Drug Hypersensitivity; Eti | 2003 |
Toxicity of local anaesthetics.
Topics: Anesthetics, Local; Animals; Bupivacaine; Cardiovascular System; Cocaine; Drug Hypersensitivity; Eti | 2003 |
Toxicity of local anaesthetics.
Topics: Anesthetics, Local; Animals; Bupivacaine; Cardiovascular System; Cocaine; Drug Hypersensitivity; Eti | 2003 |
Toxicity of local anaesthetics.
Topics: Anesthetics, Local; Animals; Bupivacaine; Cardiovascular System; Cocaine; Drug Hypersensitivity; Eti | 2003 |
Toxicity of local anaesthetics.
Topics: Anesthetics, Local; Animals; Bupivacaine; Cardiovascular System; Cocaine; Drug Hypersensitivity; Eti | 2003 |
Toxicity of local anaesthetics.
Topics: Anesthetics, Local; Animals; Bupivacaine; Cardiovascular System; Cocaine; Drug Hypersensitivity; Eti | 2003 |
What is the role of diphenhydramine in local anesthesia?
Topics: Anesthesia, Local; Anesthetics, Local; Diphenhydramine; Drug Hypersensitivity; Emergency Medical Ser | 1996 |
Medical issues and emergencies in the dermatology office.
Topics: Anaphylaxis; Anesthetics, Local; Anti-Arrhythmia Agents; Anticoagulants; Cerebrovascular Disorders; | 1997 |
An adverse reaction to local anaesthesia: report of a case.
Topics: Adult; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Diagnostic Errors; Drug Hypersensi | 1996 |
Physiology and pharmacology of local anesthetic agents.
Topics: Administration, Topical; Amides; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular System; Ce | 1973 |
Local anesthesia. 1.
Topics: Action Potentials; Anesthesia, Local; Anesthetics, Local; Animals; Cardiovascular System; Cell Membr | 1972 |
Acute and chronic toxicity of local anaesthetics.
Topics: Anesthesia, Obstetrical; Anesthetics, Local; Animals; Brain; Cats; Diazepam; Drug Hypersensitivity; | 1973 |
[N-(gamma-(4-phenoxymethylphenyl)propyl)-morpholine--a new surface anesthetic of remarkable tolerance. 6. Report on the syntheses of new compounds with local anethetic effect. 1].
Topics: Anesthetics, Local; Animals; Anti-Inflammatory Agents; Autonomic Nervous System; Bacteria; Blood Pre | 1968 |
Trials
4 trials available for lidocaine and Drug Hypersensitivity
Article | Year |
---|---|
Double-blinded comparison of diphenhydramine versus lidocaine as a local anesthetic.
Topics: Adult; Anesthetics, Local; Diphenhydramine; Double-Blind Method; Drug Hypersensitivity; Humans; Inje | 1993 |
Use of EMLA cream in a department of neonatology.
Topics: Anesthetics, Local; Drug Combinations; Drug Eruptions; Drug Hypersensitivity; Hospital Departments; | 1996 |
Randomized trial of diphenhydramine versus benzyl alcohol with epinephrine as an alternative to lidocaine local anesthesia.
Topics: Adult; Anesthetics, Local; Benzyl Alcohol; Diphenhydramine; Double-Blind Method; Drug Combinations; | 1998 |
Comparison of compounds used for intradermal anesthesia.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Benzyl Alcohols; Clinical Trials as Topic; Drug Hypers | 1976 |
Other Studies
172 other studies available for lidocaine and Drug Hypersensitivity
Article | Year |
---|---|
Anaphylactic Shock to Lidocaine: A Rare Case With Evaluation of Cross-Reactivity Between Local Anesthetics.
Topics: Anaphylaxis; Anesthetics, Local; Cross Reactions; Drug Hypersensitivity; Humans; Lidocaine | 2021 |
[Anafilaxia perioperatoria a sevoflurano, un caso muy raro].
Topics: Anaphylaxis; Anesthetics; Child; Drug Hypersensitivity; Epinephrine; Humans; Latex; Lidocaine; Male; | 2023 |
Anaphylaxis due to Perioperative Intravenous Lidocaine.
Topics: Administration, Intravenous; Aged; Allergens; Anaphylaxis; Anesthesia; Drug Hypersensitivity; Humans | 2021 |
Immediate local anesthetic reactions and diagnostic test results in pediatric patients.
Topics: Adolescent; Anesthetics, Local; Child; Child, Preschool; Drug Hypersensitivity; Female; Humans; Hype | 2021 |
Difficult Airway Management Caused by Local Anesthetic Allergy During Emergent Cesarean Delivery: A Case Report.
Topics: Adult; Airway Management; Anaphylaxis; Anesthetics, Local; Angioedema; Cesarean Section; Drug Hypers | 2017 |
Nebulized ketamine for successful management of difficult airway.
Topics: Abscess; Administration, Inhalation; Adult; Aerosols; Anti-Infective Agents; Bronchoscopes; C-Reacti | 2017 |
CAT of the Month (Critically Appraised Topics): True Allergic Reaction to Amide Local Anesthetics such as Lidocaine is Confirmed by Immunologic Testing (UT CAT# 3062).
Topics: Adult; Amides; Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Hypersensitivity, Delayed; | 2016 |
Lidocaine as a Rare and Hidden Allergen in the Perioperative Setting: A Case Report.
Topics: Allergens; Drug Hypersensitivity; Drug Interactions; Female; Humans; Lidocaine; Mepivacaine; Middle | 2019 |
Delayed and protracted allergic reaction to oral lidocaine.
Topics: Adult; Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Immunoglobulin E; Lidocaine; Skin | 2019 |
Anaphylactic reaction to intraurethral chlorhexidine: sensitisation following previous repeated uneventful administration.
Topics: Aged, 80 and over; Anaphylaxis; Anti-Infective Agents, Local; Chlorhexidine; Cystoscopy; Drug Combin | 2013 |
Lidocaine contact allergy is becoming more prevalent.
Topics: Anesthesia, Local; Benzocaine; British Columbia; Dermatitis, Allergic Contact; Drug Hypersensitivity | 2014 |
Stent dislodgement induced by a vasodilator used for severe coronary artery spasm caused by Kounis syndrome.
Topics: Aged; Anesthetics, Local; Coronary Vasospasm; Device Removal; Drug Hypersensitivity; Foreign-Body Mi | 2016 |
Hoigne syndrome: a little-known adverse effect of lidocaine.
Topics: Acute Disease; Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Lidocaine; Syndrome; Young | 2016 |
Hyaluronidase hypersensitivity: A rare complication of peribulbar block.
Topics: Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Cataract Extraction; Drug Hypersensitivity; | 2016 |
A case of severe NSAID exacerbated respiratory disease (NERD) following a dental procedure in a child.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Cyclooxygenase 2 Inhibitors; Drug Hyper | 2016 |
[Clinical examination of challenge test to local anesthetics].
Topics: Adult; Aged; Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Lidocaine; Male; Middle Aged | 2009 |
Acupuncture anesthesia for complicated dental extractions in patients with lidocaine allergy.
Topics: Acupuncture Analgesia; Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Lidocaine; Middle | 2009 |
Kounis syndrome presenting with cardiogenic shock.
Topics: Anaphylaxis; Anesthetics, Local; Coronary Angiography; Coronary Vasospasm; Drug Hypersensitivity; El | 2011 |
Severe adverse reactions to dental local anaesthetics: systemic reactions.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Anesthesia, Den | 2011 |
Acute bullous irritant contact dermatitis caused by EMLA® cream.
Topics: Acute Disease; Anesthetics, Local; Blister; Dermatitis, Irritant; Drug Hypersensitivity; Eczema; Emo | 2011 |
An immediate hypersensitivity reaction caused by tolperisone hydrochloride.
Topics: Drug Hypersensitivity; Edema; Erythema; Humans; Lidocaine; Male; Middle Aged; Muscle Relaxants, Cent | 2011 |
Drug fever caused by eutectic mixture of local anesthetic cream.
Topics: Debridement; Drug Hypersensitivity; Drug Interactions; Female; Fever; Humans; Leg Ulcer; Lidocaine; | 2011 |
IgE-mediated reaction to local anaesthetics.
Topics: Adult; Anesthesia, Epidural; Anesthetics, Local; Bupivacaine; Cesarean Section; Drug Hypersensitivit | 2013 |
Recurrent facial swelling following dental procedures.
Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Drug Hypersensitivity; Edema; Face; Humans; Hypersens | 2002 |
Confirming false adverse reactions to drugs by performing individualized, randomized trials.
Topics: Administration, Oral; Adult; Anesthetics, Local; Codeine; Dimenhydrinate; Double-Blind Method; Drug | 2002 |
An unusual symptom of lidocaine allergy. Report of a case.
Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Lidocaine; Vis | 2002 |
Delayed-type hypersensitivity to lidocaine.
Topics: Adult; Aged; Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Hypersensitivity, Delayed; I | 2003 |
Look elsewhere for the culprit.
Topics: Anesthesia, Dental; Anesthetics, Local; Drug Hypersensitivity; Humans; Lidocaine; Reproducibility of | 2003 |
Cutaneous lidocaine allergy confirmed by patch testing.
Topics: Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Lidocaine; Middle Aged; Patch Tests | 2002 |
[General toxic syndromes caused by local anesthetics].
Topics: Anesthetics; Anesthetics, Local; Cardiovascular Agents; Drug Hypersensitivity; Humans; Lidocaine; Pr | 1963 |
[BRONCHIAL ASTHMA AS A RESULT OF LIDOCAINE ALLERGY].
Topics: Asthma; Drug Hypersensitivity; Humans; Lidocaine; Sinusitis; Skin Tests; Surgical Procedures, Operat | 1963 |
[CASES OF SHOCK-LIKE CONDITIONS. (3) CLINICAL CASES OF SHOCK-LIKE CONDITIONS CAUSED BY DRUGS].
Topics: Adolescent; Child; Drug Hypersensitivity; Lidocaine; Otolaryngology; Penicillins; Procaine; Shock; S | 1963 |
[CASES OF SHOCK-LIKE CONDITIONS. (6)].
Topics: Adenoidectomy; Child; Cocaine; Drug Hypersensitivity; Lidocaine; Otolaryngology; Shock; Shock, Septi | 1963 |
[CASES OF SHOCK-LIKE CONDITIONS. (8)].
Topics: Drug Hypersensitivity; Heart Massage; Infant; Lidocaine; Otolaryngology; Resuscitation; Shock; Shock | 1963 |
[CASE OF SUCCESSFUL TREATMENT OF SHOCK IN TONSILLECTOMY AND MEASURES FOR PREVENTING IT].
Topics: Blood Sedimentation; Blood Transfusion; Caffeine; Cyanosis; Drug Hypersensitivity; Electrocardiograp | 1963 |
[CASE OF SHOCK CAUSED BY LOCAL ANESTHESIA].
Topics: Anesthesia, Local; Blood Transfusion; Cocaine; Drug Hypersensitivity; Lidocaine; Oxygen Inhalation T | 1963 |
[5 RECENT CASES OF LOCAL ANESTHETIC TOXICITY IN TONSILLECTOMY].
Topics: Anesthesia, Local; Anesthetics, Local; Child; Cocaine; Drug Hypersensitivity; Lidocaine; Pharmacolog | 1963 |
USE OF TRIPELENNAMINE AND DIPHENHYDRAMINE AS LOCAL ANESTHETICS.
Topics: Anesthetics; Anesthetics, Local; Biomedical Research; Dental Care; Diphenhydramine; Drug Hypersensit | 1964 |
DIPHENHYDRAMINE HYDROCHLORIDE (BENADRYL) AS A LOCAL ANESTHETIC IN PROCAINE AND LIDOCAINE SENSITIVE PATIENTS.
Topics: Anesthesia, Dental; Anesthesia, Local; Anesthetics; Anesthetics, Local; Diphenhydramine; Drug Hypers | 1964 |
CONDUCTION ANESTHESIA USING DIPHENHYDRAMINE HYDROCHLORIDE.
Topics: Anesthesia; Anesthesia, Conduction; Diphenhydramine; Drug Hypersensitivity; Humans; Lidocaine; Pharm | 1964 |
MEDICAL EMERGENCIES IN THE X-RAY DEPARTMENT PREVENTION AND TREATMENT.
Topics: Anesthesia; Anesthetics; Anesthetics, Local; Angioedema; Barium Sulfate; Contrast Media; Drug Hypers | 1964 |
TOXIC REACTIONS TO LOCAL ANESTHETICS.
Topics: Anesthetics, Local; Cardiovascular Agents; Drug Hypersensitivity; Lidocaine; Postoperative Complicat | 1965 |
[On lidocaine allergy].
Topics: Drug Hypersensitivity; Humans; Hypersensitivity; Immune System Diseases; Lidocaine | 1961 |
Evaluation of adverse reactions to local anesthetics: experience with 236 patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Bupivacaine; Child; Child, Preschool | 2003 |
Bone scan 14 days after a toxic lignocaine reaction.
Topics: Adult; Anaphylaxis; Angioedema; Diagnosis, Differential; Drug Hypersensitivity; Female; Humans; Inci | 2004 |
EMLA toxicity after application for allergy skin testing.
Topics: Anesthetics, Local; Child, Preschool; Drug Hypersensitivity; Eczema; Female; Humans; Lidocaine; Lido | 2004 |
Evaluation of re-challenge in patients with suspected lidocaine allergy.
Topics: Drug Hypersensitivity; Female; France; Humans; Injections, Subcutaneous; Lidocaine; Male; Predictive | 2004 |
Hyaluronidase allergy after peribulbar anesthesia with orbital inflammation.
Topics: Aged; Anesthesia, Local; Anesthetics, Combined; Bupivacaine; Cellulitis; Drug Hypersensitivity; Fema | 2004 |
[The problems of multiple-chemical sensitivity patients in using medicinal drugs].
Topics: Adult; Aspirin; Caffeine; Contraindications; Drug Hypersensitivity; Drug-Related Side Effects and Ad | 2004 |
A primigravida allegedly allergic to local anaesthetics.
Topics: Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Lidocaine; Pregnancy; Vagina | 2004 |
Allergic reaction to epinephrine preparation in 2% lidocaine: two case reports.
Topics: Adolescent; Anesthetics, Local; Arrhythmias, Cardiac; Drug Hypersensitivity; Edema; Epinephrine; Fem | 2004 |
Use of preservative-free lidocaine for cataract surgery in a patient allergic to "caines".
Topics: Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Cataract Extraction; Drug Hypersensi | 2005 |
Hyaluronidase allergy after peribulbar anesthesia with orbital inflammation.
Topics: Anesthesia, Local; Anesthetics, Combined; Bupivacaine; Cellulitis; Drug Hypersensitivity; Glucocorti | 2005 |
Thoracotomy in a patient with a history of local anesthetic allergy.
Topics: Adult; Anesthesia, Epidural; Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Lidocaine; T | 2005 |
Anesthetic management of a labouring parturient with urticaria pigmentosa.
Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Intravenous; | 2006 |
Tryptase as severity marker in drug provocation tests.
Topics: Acetaminophen; Adolescent; Adult; Aspirin; Diclofenac; Drug Hypersensitivity; Female; Humans; Lidoca | 2006 |
Lidocaine hypersensitivity after subconjunctival injection.
Topics: Abscess; Anesthetics, Local; Conjunctiva; Corneal Diseases; Drug Hypersensitivity; Humans; Injection | 2006 |
IgE-mediated hypersensitivity reaction to lignocaine - a case report.
Topics: Anesthesia, Dental; Anesthetics, Local; Child; Drug Hypersensitivity; Female; Humans; Hypersensitivi | 2005 |
Obtaining a contact lens acquired electroretinogram in the presence of topical anesthetic hypersensitivity.
Topics: Adult; Anesthetics, Local; Contact Lenses, Hydrophilic; Drug Hypersensitivity; Electroretinography; | 2008 |
Case reports: type I hypersensitivity to lidocaine.
Topics: Acne Keloid; Adult; Anesthetics, Local; Drug Hypersensitivity; Humans; Hypersensitivity, Immediate; | 2007 |
Dental anesthesia with lidocaine hydrochloride for children with intractable asthma and associated allergies.
Topics: Adolescent; Anesthesia, Dental; Anesthesia, Local; Asthma; Child; Child, Institutionalized; Dentistr | 1967 |
Unusual reactions to tetanus toxoid.
Topics: Adult; Drug Hypersensitivity; Female; Humans; Lidocaine; Middle Aged; Tetanus Toxoid; Urticaria | 1967 |
[Warnings issued by the Ministry of Health on the safety of antibiotics, anti-inflammatory analgesics and lidocaine].
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Drug Hypersensitivity; Humans; Lidoc | 1984 |
Molecular basis for the antigenicity of lidocaine analogs: tocainide and mexiletine.
Topics: Aged; Anti-Arrhythmia Agents; Antigens; Cross Reactions; Drug Hypersensitivity; Female; Humans; Intr | 1984 |
An unusual skin reaction following local anesthetic injection. Review of the literature and report of four cases.
Topics: Arthus Reaction; Child; Drug Eruptions; Drug Hypersensitivity; Drug Tolerance; Erythema; Female; Hum | 1980 |
[Shock syndrome caused by lidocaine hydrochloride (Xylocitin)].
Topics: Anaphylaxis; Drug Hypersensitivity; Hemodynamics; Humans; Lidocaine; Male; Middle Aged | 1984 |
[Local anesthesia and Para group allergy].
Topics: Anesthetics, Local; Chemical Phenomena; Chemistry; Drug Hypersensitivity; Humans; Lidocaine; Mepivac | 1983 |
[A rare chin skin reaction following infiltration anesthesia with 2% xylocaine. Report of 3 cases].
Topics: Anesthesia, Dental; Anesthesia, Local; Child; Child, Preschool; Drug Hypersensitivity; Female; Human | 1984 |
[Toxic and allergic reactions to local anesthetics].
Topics: Bupivacaine; Drug Hypersensitivity; Humans; Lidocaine; Procaine | 1984 |
Assessment of allergy to local anesthetic.
Topics: Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Lidocaine; Middle Aged; Parabens; Skin Te | 1983 |
Hypersensitivity to local anaesthetics: a direct challenge test with lignocaine for definitive diagnosis.
Topics: Adolescent; Adult; Drug Hypersensitivity; Female; Humans; Lidocaine; Male; Middle Aged | 1982 |
Hypersensitivity to local anaesthetics: a direct challenge test with lignocaine for definitive diagnosis.
Topics: Anesthetics, Local; Drug Hypersensitivity; Humans; Lidocaine; Skin Tests | 1982 |
Dental drugs and anaphylactic reactions. Report of a case.
Topics: Adult; Anaphylaxis; Anesthesia, Dental; Aspirin; Codeine; Drug Combinations; Drug Hypersensitivity; | 1980 |
The relationship between in vivo and in vitro reactivity of patients with a history of allergy to local anaesthetics.
Topics: Adolescent; Adult; Anesthetics, Local; Drug Hypersensitivity; Female; Humans; In Vitro Techniques; I | 1982 |
Hypersensitivity to certain drugs in a rural population.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Drug Hypersensitivity; Humans; India; Infant; Infa | 1981 |
Problems of peppermint-flavored lidocaine.
Topics: Drug Hypersensitivity; Flavoring Agents; Humans; Lidocaine; Pharmaceutic Aids | 1980 |
[Minor toxic effects of local anaesthetics. 7 cases (author's transl)].
Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Anxiety; Drug Hypersensitivity; Female; Humans; Hyper | 1980 |
Allergic hypersensitivity to lidocaine hydrochloride.
Topics: Adolescent; Adult; Anesthesia, Dental; Child; Drug Hypersensitivity; Female; Humans; Lidocaine; Male | 1980 |
Allergy to local anaesthetics.
Topics: Anaphylaxis; Child; Drug Hypersensitivity; Female; Humans; Lidocaine | 1980 |
Identifying true lidocaine allergy.
Topics: Anesthesia, Dental; Anesthesia, Local; Dental Anxiety; Diagnosis, Differential; Drug Hypersensitivit | 1994 |
Identifying true lidocaine allergy.
Topics: Anesthesia, Dental; Anesthesia, Local; Dental Anxiety; Diagnosis, Differential; Drug Hypersensitivit | 1994 |
Identifying true lidocaine allergy.
Topics: Anesthesia, Dental; Anesthesia, Local; Dental Anxiety; Diagnosis, Differential; Drug Hypersensitivit | 1994 |
Identifying true lidocaine allergy.
Topics: Anesthesia, Dental; Anesthesia, Local; Dental Anxiety; Diagnosis, Differential; Drug Hypersensitivit | 1994 |
EMLA cream-induced allergic contact dermatitis: a role for prilocaine as an immunogen.
Topics: Aged; Dermatitis, Allergic Contact; Drug Combinations; Drug Hypersensitivity; Female; Humans; Lidoca | 1995 |
Skin testing after anaphylactoid reactions to dental local anesthetics. A comparison with controls.
Topics: Adolescent; Adult; Aged; Anaphylaxis; Anesthesia, Dental; Anesthetics, Local; Chi-Square Distributio | 1993 |
Delayed-type hypersensitivity after subcutaneous administration of amide anesthetic.
Topics: Aged; Amides; Anesthetics, Local; Drug Eruptions; Drug Hypersensitivity; Female; Humans; Hypersensit | 1996 |
Lignocaine toxicity following pleurodesis.
Topics: Adult; Drug Hypersensitivity; Humans; Hypersensitivity, Immediate; Lidocaine; Male; Middle Aged; Ple | 1995 |
Unusual complications of intermittent self-catheterisation in spinal cord injury patients.
Topics: Adult; Anesthetics, Local; Drug Hypersensitivity; Equipment Failure; Female; Humans; Lidocaine; Male | 1996 |
T cell reactions in patients showing adverse immune reactions to drugs.
Topics: Adult; Anesthetics, Local; Anti-Infective Agents; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphoc | 1996 |
Allergic reaction caused by local anesthetic agents belonging to the amide group.
Topics: Adult; Allergens; Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Immunoglobulin E; Lidoc | 1997 |
How to avoid local anaesthetic toxicity.
Topics: Adult; Aged; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Body Weight; Child; Child, P | 1998 |
Allele-unrestricted presentation of lidocaine by HLA-DR molecules to specific alphabeta+ T cell clones.
Topics: Adult; Alleles; Anesthetics, Local; Animals; Antigen-Presenting Cells; Clone Cells; Drug Hypersensit | 1998 |
Lignocaine and anaesthetic allergy.
Topics: Adult; Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Incidence; Lidocaine; Prilocaine; | 1998 |
Recognition of local anesthetics by alphabeta+ T cells.
Topics: Anesthetics, Local; Cell Line; Clone Cells; Cross Reactions; Drug Hypersensitivity; Epitopes; Humans | 1999 |
Sight-threatening acute orbital swelling from peribulbar local anesthesia.
Topics: Acute Disease; Aged; Anesthetics, Local; Drug Hypersensitivity; Edema; Female; Follow-Up Studies; Gl | 1999 |
Allergic reactions to lignocaine.
Topics: Adult; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Diagnosis, Differential; Drug Hype | 1999 |
Anaphylactic reaction to lidocaine.
Topics: Adolescent; Anaphylaxis; Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Hypersensitivity | 1999 |
Adverse reactions possibly associated with the use of Emla cream.
Topics: Anesthetics, Combined; Anesthetics, Local; Child; Drug Hypersensitivity; Female; Humans; Lidocaine; | 1999 |
[The use of EMLA cream in pediatrics].
Topics: Anesthetics, Combined; Anesthetics, Local; Child; Drug Hypersensitivity; Humans; Lidocaine; Lidocain | 1999 |
An adverse effect of carboxymethylcellulose in lidocaine jelly.
Topics: Aged; Anesthetics, Local; Carboxymethylcellulose Sodium; Drug Hypersensitivity; Female; Gels; Humans | 1999 |
Lidocaine toxicity in a student undergoing upper gastrointestinal endoscopy.
Topics: Adult; Anesthetics, Local; Drug Hypersensitivity; Fatal Outcome; Humans; Lidocaine; Male | 2000 |
Adverse reaction to dental local anaesthetic injection--'allergy' is not the cause.
Topics: Anesthesia, Dental; Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Immunologic Tests; In | 2000 |
Local anaesthetics.
Topics: Anesthesia, Dental; Anesthetics, Local; Drug Hypersensitivity; Humans; Lidocaine; Maximum Tolerated | 2000 |
Simultaneous [correction of Spontaneous] allergy to ampicillin and local anesthetics.
Topics: Ampicillin; Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Hypersensitivity, Delayed; In | 2001 |
Just the berries. Allergy to local anesthetics.
Topics: Aged; Anesthetics, Local; Drug Hypersensitivity; Humans; Lacerations; Lidocaine; Male; Skin Test End | 2001 |
Allergic response to metabisulfite in lidocaine anesthetic solution.
Topics: Adult; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Antioxidants; Drug Hypersensitivit | 2001 |
Post-extraction complications seen at a referral dental clinic in Dar Es Salaam, Tanzania.
Topics: Abscess; Adolescent; Adult; Ambulatory Surgical Procedures; Anesthesia, Dental; Anesthetics, Local; | 2001 |
A pregnant woman with previous anaphylactic reaction to local anesthetics: a case report.
Topics: Adult; Anaphylaxis; Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Lidocaine; Pregnancy; | 2001 |
Sensitivity to local anaesthetics among asthmatic children.
Topics: Adolescent; Allergens; Anesthetics, Local; Animals; Asthma; Child; Drug Hypersensitivity; Female; Hu | 2001 |
Evaluating a dental patient for local anesthesia allergy.
Topics: Aged; Allergens; Anesthesia, Dental; Anesthetics, Local; Drug Hypersensitivity; Exanthema; Humans; H | 2002 |
[A study of allergy to local anesthetics using the lymphoblast transformation test].
Topics: Adult; Anesthetics, Local; Chemical Phenomena; Chemistry; Drug Hypersensitivity; Female; Humans; Lid | 1976 |
Letter: Presumed generalized exfoliative dermatitis to lidocaine.
Topics: Adult; Anesthesia, Dental; Dermatitis, Exfoliative; Drug Hypersensitivity; Humans; Lidocaine; Male | 1975 |
Discussion of sensitivity to preservatives in anesthetics.
Topics: Adult; Anesthesia, Dental; Drug Hypersensitivity; Female; Humans; Lidocaine; Parabens; Pharmaceutic | 1978 |
Sensitivity to lignocaine.
Topics: Anesthesia, Local; Drug Hypersensitivity; Humans; Lidocaine; Skin Tests | 1979 |
Sensitivity to lignocaine.
Topics: Aged; Drug Hypersensitivity; Humans; Lidocaine; Male; Syncope | 1977 |
[Apropos of a severe complication of local anesthesia using xylocaine].
Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Drug Hypersensitivity; Female; Hiccup; Humans; Lidoca | 1977 |
Vertical pendular nystagmus in chronic myositis of medial and lateral rectus.
Topics: Adult; Chronic Disease; Diplopia; Drug Hypersensitivity; Female; Humans; Lidocaine; Mepivacaine; Myo | 1978 |
Adverse reactions to local anaesthetics and vasoconstrictor drugs.
Topics: Anaphylaxis; Anesthesia, Dental; Anesthetics, Local; Arteriosclerosis; Blood Pressure; Coronary Dise | 1975 |
Deaths from paracervical anesthesia used for first-trimester abortion, 1972-1975.
Topics: Abortion, Induced; Adolescent; Adult; Anesthesia, Obstetrical; Cervix Uteri; Dose-Response Relations | 1976 |
Deaths from paracervical anesthesia used for first-trimester abortion, 1972-1975.
Topics: Abortion, Induced; Adolescent; Adult; Anesthesia, Obstetrical; Cervix Uteri; Dose-Response Relations | 1976 |
Deaths from paracervical anesthesia used for first-trimester abortion, 1972-1975.
Topics: Abortion, Induced; Adolescent; Adult; Anesthesia, Obstetrical; Cervix Uteri; Dose-Response Relations | 1976 |
Deaths from paracervical anesthesia used for first-trimester abortion, 1972-1975.
Topics: Abortion, Induced; Adolescent; Adult; Anesthesia, Obstetrical; Cervix Uteri; Dose-Response Relations | 1976 |
Allergic reaction to lignocaine. A case report.
Topics: Anesthesia, Dental; Anesthesia, Local; Child; Drug Hypersensitivity; Edema; Eyelid Diseases; Female; | 1975 |
[A case of early-type hypersesitivity to lignocaine].
Topics: Adult; Anesthesia, Dental; Drug Hypersensitivity; Edema; Female; Humans; Lidocaine | 1976 |
[Clinical and experimental contribution to the pathogenesis of acute life-threatening incidents following neck anesthesia].
Topics: Acute Disease; Anaphylaxis; Anesthesia, Epidural; Anesthesia, Local; Anesthetics; Drug Hypersensitiv | 1975 |
Letter: Deaths due to local analgesia in dentistry.
Topics: Anesthesia, Dental; Anesthesia, Intravenous; Carotid Arteries; Drug Hypersensitivity; Humans; Lidoca | 1975 |
PAF acether release on antigenic challenge. A method for the investigation of drug allergic reactions.
Topics: Antigens; Aspirin; Drug Hypersensitivity; Humans; Immunoglobulin E; Leukocytes; Lidocaine; Lymphocyt | 1992 |
Type IV allergy to amide-type local anesthetics.
Topics: Anesthetics, Local; Cross Reactions; Drug Hypersensitivity; Female; Humans; Hypersensitivity, Delaye | 1991 |
[A case of eosinophilic pneumonitis with drug hypersensitivity].
Topics: Alveolitis, Extrinsic Allergic; Atropine; Cefixime; Cefotaxime; Drug Hypersensitivity; Female; Human | 1991 |
Tocainide: interstitial pneumonitis.
Topics: Aged; Anti-Arrhythmia Agents; Drug Hypersensitivity; Humans; Lidocaine; Male; Pulmonary Fibrosis; To | 1990 |
Local anesthesia in dermatologic surgery.
Topics: Anesthesia, Local; Dermatologic Surgical Procedures; Drug Hypersensitivity; Humans; Lidocaine; Skin | 1990 |
Supersensitivity to subcutaneous lidocaine.
Topics: Administration, Cutaneous; Drug Hypersensitivity; Humans; Lidocaine; Male; Middle Aged | 1990 |
[Management of suspected allergy to lidocaine].
Topics: Drug Hypersensitivity; Female; Histamine Release; Humans; Lidocaine; Lymphocyte Activation; Postoper | 1986 |
Local anesthetic intolerance due to metabisulfite.
Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Drug Combinations; Drug Hypersensitivity; Female; Hum | 1989 |
Tocainide: a severe adverse reaction.
Topics: Aged; Anti-Arrhythmia Agents; Drug Eruptions; Drug Hypersensitivity; Humans; Lidocaine; Male; Tocain | 1988 |
Tocainide-induced granulomatous hepatitis.
Topics: Anti-Arrhythmia Agents; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Granuloma; Hu | 1986 |
Fatal bronchospasm after topical lignocaine before bronchoscopy.
Topics: Administration, Topical; Aged; Bronchial Spasm; Bronchoscopy; Drug Hypersensitivity; Humans; Lidocai | 1987 |
Fatal bronchospasm after topical lignocaine before bronchoscopy.
Topics: Bronchial Spasm; Bronchoscopy; Drug Hypersensitivity; Humans; Lidocaine; Male | 1987 |
An answer for a questionable allergy to local anesthetics.
Topics: Drug Hypersensitivity; Humans; Lidocaine; Parabens | 1988 |
Considerations in differential diagnosis of adverse reactions to local anesthetic: report of case.
Topics: Anesthesia, Dental; Anesthesia, Local; Diagnosis, Differential; Drug Hypersensitivity; Female; Human | 1986 |
Provocative challenge with local anesthetics in patients with a prior history of reaction.
Topics: Anaphylaxis; Anesthetics, Local; Drug Hypersensitivity; Humans; Intradermal Tests; Lidocaine; Procai | 1987 |
[A pediatric case of lidocaine hypersensitivity].
Topics: Adolescent; Anesthesia, Dental; Drug Hypersensitivity; Female; Humans; Lidocaine | 1987 |
Local anesthesia. Implications for the perioperative nurse.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Documentation; Drug Hypersensitivity; Female; Humans; | 1987 |
[Allergic angioedema after local dental anesthesia and a hyaluronidase-containing preanesthetic injection solution].
Topics: Adult; Anesthesia, Dental; Anesthesia, Local; Angioedema; Drug Hypersensitivity; Female; Humans; Hya | 1986 |
Allergy to lidocaine and mepivacaine: report of a case.
Topics: Adult; Drug Hypersensitivity; Humans; Hypersensitivity, Immediate; Lidocaine; Male; Mepivacaine | 1985 |
Anaphylactic reaction to lidocaine.
Topics: Adult; Anaphylaxis; Bupivacaine; Drug Evaluation; Drug Hypersensitivity; Female; Humans; Intradermal | 1986 |
Nasal test for hypersensitivity. Including a positive reaction to lignocaine.
Topics: Adult; Anesthesia, Dental; Drug Hypersensitivity; Female; Humans; Lidocaine; Methods; Nose; Solution | 1971 |
Lignocaine hypersensitivity.
Topics: Anesthesia, Local; Drug Hypersensitivity; Humans; Lidocaine; Lymphocyte Activation; Skin Tests | 1971 |
The rat mast cell degranulation assay as an in vitro allergy test.
Topics: Age Factors; Animals; Cycloserine; Cytoplasmic Granules; Dextrans; Drug Hypersensitivity; Histamine | 1974 |
[Complications of regional anaesthesia and their treatment (author's transl)].
Topics: Adrenal Cortex Hormones; Anesthesia, Local; Apnea; Barbiturates; Bradycardia; Bupivacaine; Diagnosis | 1973 |
Local anaesthetic sensitivity. Case report.
Topics: Antigen-Antibody Reactions; Asthma; Drug Hypersensitivity; Edema; Epinephrine; Female; Humans; Hyper | 1972 |
[A case of lidocaine allergy].
Topics: Drug Hypersensitivity; Humans; Lidocaine; Skin Tests | 1972 |
[Lidocaine hypersensitivity].
Topics: Adolescent; Adult; Anesthesia, Dental; Drug Hypersensitivity; Humans; Lidocaine; Male; Skin Tests | 1973 |
Sensitivity to local anaesthetic.
Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Benzoates; Drug Hypersensitivity; Female; Humans; Lid | 1972 |
Local anaesthetic sensitivity. Case report.
Topics: Anesthesia, Dental; Drug Hypersensitivity; Lidocaine | 1972 |
A case of lignocaine hypersensitivity.
Topics: Adolescent; Drug Hypersensitivity; Female; Humans; Lidocaine; Nasal Mucosa; Procaine; Skin Tests; Ur | 1973 |
Local anesthetic reactions: prevention, diagnosis, treatment.
Topics: Aged; Anesthesia, Local; Drug Hypersensitivity; Female; Humans; Lidocaine; Male; Middle Aged; Tetrac | 1974 |
The effect of local anesthesia with epinephrine on skin flap survival.
Topics: Anesthesia, Local; Animals; Drug Hypersensitivity; Epinephrine; Lidocaine; Necrosis; Skin; Skin Tran | 1974 |
[Iatrogenic lesion in ophthalmologic anesthesia].
Topics: Adult; Aged; Anesthesia, General; Anesthesia, Local; Anesthetics; Anesthetics, Local; Atropine; Blin | 1972 |
Curettage as an office procedure.
Topics: Abortion, Therapeutic; Anesthesia, Local; Costs and Cost Analysis; Curettage; Dilatation; Drug Hyper | 1974 |
Fever, vomiting, and liver dysfunction with procainamide therapy.
Topics: Ampicillin; Blood; Chemical and Drug Induced Liver Injury; Digitalis; Drug Hypersensitivity; Female; | 1974 |
Recent experiences with intravenous regional anesthesia in limbs.
Topics: Anesthesia, Conduction; Anesthesia, Intravenous; Arm; Drug Hypersensitivity; Foot; Hand; Humans; Leg | 1972 |
Extreme epinephrine sensitivity with a general anesthesia.
Topics: Adult; Anesthesia, Inhalation; Arrhythmias, Cardiac; Blood Pressure; Child; Drug Hypersensitivity; D | 1972 |
An acute immune response to intra-articular injection of osmium tetroxide.
Topics: Arthritis, Rheumatoid; Creatinine; Drug Hypersensitivity; Female; Humans; Injections, Intra-Articula | 1971 |
Evaluation of patients with history of allergy to local anesthetic drugs.
Topics: Adolescent; Adult; Aged; Anesthetics, Local; Child; Drug Hypersensitivity; Female; Humans; Lidocaine | 1971 |
Local anaesthetics.
Topics: Amides; Anesthetics, Local; Brain Edema; Cardiovascular Diseases; Central Nervous System Diseases; C | 1971 |
Lidocaine hypersensitivity: report of a case.
Topics: Adult; Anesthesia, Dental; Drug Hypersensitivity; Epinephrine; Female; Humans; Lidocaine | 1967 |
Hypersensitivity to lidocaine hydrochloride. Report of a case.
Topics: Adult; Drug Hypersensitivity; Humans; Lidocaine; Male | 1969 |
[Studies of the skin test of local anesthetic drugs and the interview test of outpatients in dental clinical offices].
Topics: Drug Hypersensitivity; Lidocaine; Skin Tests | 1969 |
[Allergic skin reactions to topical anesthetics in patients with bronchial asthma].
Topics: Asthma; Drug Hypersensitivity; Humans; Lidocaine; Procaine; Skin Tests | 1971 |
More about the "allergic reaction to lidocaine".
Topics: Drug Hypersensitivity; Humans; Lidocaine | 1970 |
An "allergic" reaction?
Topics: Anesthesia, Local; Drug Hypersensitivity; Humans; Lidocaine; Skin Tests | 1970 |
[Prothanon eyedrops. 1. Results of experimental animal and orientative clinical studies].
Topics: Anesthetics, Local; Animals; Conjunctivitis; Cornea; Drug Hypersensitivity; Drug Tolerance; Eye; Hum | 1970 |
Hypersensitivity reaction to lignocaine.
Topics: Drug Hypersensitivity; Female; Humans; Lidocaine | 1971 |
[Test for drug sensitization in patients with cerebral stroke].
Topics: Adult; Aged; Cerebrovascular Disorders; Drug Hypersensitivity; Female; Hemiplegia; Humans; Lidocaine | 1969 |
A suspected allergic reaction to lidocaine.
Topics: Anaphylaxis; Drug Hypersensitivity; Humans; Hypersensitivity, Delayed; Lidocaine; Male; Middle Aged; | 1969 |
Diphenhydramine for local anesthesia in "caine" sensitive patients. A case report.
Topics: Adult; Anesthesia, Local; Diphenhydramine; Drug Hypersensitivity; Female; Humans; Lidocaine; Warts | 1966 |
Anaphylaxis from alphazurine 2G during lymphography.
Topics: Adult; Coloring Agents; Diphenhydramine; Drug Hypersensitivity; Epinephrine; Hodgkin Disease; Humans | 1966 |