Page last updated: 2024-10-28

lidocaine and Drug Hypersensitivity

lidocaine has been researched along with Drug Hypersensitivity in 188 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Drug Hypersensitivity: Immunologically mediated adverse reactions to medicinal substances used legally or illegally.

Research Excerpts

ExcerptRelevanceReference
"Lidocaine hydrochloride is an amide-type local anesthetic, commonly used for facial plastic as well as other surgical procedures."5.27Anaphylactic reaction to lidocaine. ( Cave, RH; Kennedy, KS, 1986)
" The diphenhydramine median pain score was 55 mm, compared with 12."5.08Randomized trial of diphenhydramine versus benzyl alcohol with epinephrine as an alternative to lidocaine local anesthesia. ( Bartfield, JM; Jandreau, SW; Raccio-Robak, N, 1998)
" We discuss the literature that has influenced current office behavior regarding endocarditis prophylaxis, the use of electrosurgery with pacemakers, arrhythmogenic drug interactions, vasovagal syncope, lidocaine "allergy," and bleeding complications from oral anticoagulants."4.79Medical issues and emergencies in the dermatology office. ( Fader, DJ; Johnson, TM, 1997)
" On the second occasion, he received only sevoflurane and presented anaphylaxis, treated with intramuscular adrenaline."4.31[Anafilaxia perioperatoria a sevoflurano, un caso muy raro]. ( González-Vallejo, AG; Hernandez-López, E, 2023)
"Allergic contact dermatitis (ACD) to lidocaine is rising in prevalence."3.80Lidocaine contact allergy is becoming more prevalent. ( de Gannes, G; Kossintseva, I; To, D, 2014)
"We report a rare case of hypersensitivity in a 63-year-old man who received subconjunctival lidocaine, cefazolin, and gentamicin for corneal abscess."3.73Lidocaine hypersensitivity after subconjunctival injection. ( Levy, J; Lifshitz, T, 2006)
"A 43-year-old woman with a history of lidocaine allergy required dermatologic surgery during pregnancy."3.71A pregnant woman with previous anaphylactic reaction to local anesthetics: a case report. ( Birnbach, DJ; Browne, IM, 2001)
"The patient described here experienced an acute anaphylactic reaction after receiving parenteral lidocaine, oral aspirin, codeine, and penicillin following routine dental treatment."3.66Dental drugs and anaphylactic reactions. Report of a case. ( Gill, C; Michaelides, PL, 1980)
"A 39-year-old man developed allergic hypersensitivity to lidocaine hydrochloride and showed urticarial dermographism."3.66Allergic hypersensitivity to lidocaine hydrochloride. ( Chin, TM; Fellner, MJ, 1980)
"A 38-year-old white woman developed left medical rectus myositis possibly due to an immune response to mepivacaine (Carbocaine) injected around her upper left first molar."3.66Vertical pendular nystagmus in chronic myositis of medial and lateral rectus. ( Goldberg, RT, 1978)
"However type I hypersensitivity to lignocaine is rare and there have been very few cases reported in the literature."1.33IgE-mediated hypersensitivity reaction to lignocaine - a case report. ( Gendeh, BS; Mujahid, SH; Noormalin, A; Rosmilah, M; Shahnaz, M, 2005)
"Lidocaine is an anaesthetic agent used worldwide in various clinical specialties."1.32Evaluation of re-challenge in patients with suspected lidocaine allergy. ( Amsler, E; Aractingi, S; Flahault, A; Mathelier-Fusade, P, 2004)
"Patients with drug allergy show a specific immune response to drugs."1.30Recognition of local anesthetics by alphabeta+ T cells. ( Hari, Y; Pichler, WJ; Schnyder, B; von Greyerz, S; Zanni, MP, 1999)
"A young woman was found to have a true type I hypersensitivity to lignocaine."1.30Allergic reactions to lignocaine. ( Ball, IA, 1999)
"In 87 of the 90 patients with suspected anaphylactoid reactions to local anesthetic agents, negative skin reactions to at least one of the agents allowed intrabuccal challenge and subsequent recommendation of an agent for future use."1.29Skin testing after anaphylactoid reactions to dental local anesthetics. A comparison with controls. ( Challacombe, SJ; Hodgson, TA; Shirlaw, PJ, 1993)
"Tocainide is a primary analog of lidocaine with antiarrhythmic properties used to treat ventricular rhythm disorders."1.27Tocainide: a severe adverse reaction. ( DeSimone, A; Dunn, JM; Groth, PE, 1988)
" We retrospectively reviewed all our consultations for evaluation of local anesthetic allergy from 1965 to 1985 to assess the safety and efficacy of skin testing and provocative test dosing with a variety of local anesthetic agents."1.27Provocative challenge with local anesthetics in patients with a prior history of reaction. ( Chandler, MJ; Grammer, LC; Patterson, R, 1987)
"Lidocaine hydrochloride is an amide-type local anesthetic, commonly used for facial plastic as well as other surgical procedures."1.27Anaphylactic reaction to lidocaine. ( Cave, RH; Kennedy, KS, 1986)
"In a study of 7 cases of adverse reactions to local anaesthetics the early symptoms of toxicity (malaise, anxiety, feeling of impending death, peripheral paresthesias and tachycardia) are reviewed."1.26[Minor toxic effects of local anaesthetics. 7 cases (author's transl)]. ( Dry, J; Leynadier, F, 1980)

Research

Studies (188)

TimeframeStudies, this research(%)All Research%
pre-199097 (51.60)18.7374
1990's30 (15.96)18.2507
2000's37 (19.68)29.6817
2010's19 (10.11)24.3611
2020's5 (2.66)2.80

Authors

AuthorsStudies
Barradas Lopes, J1
Reis Ferreira, A1
Sousa, MJ1
Cadinha, S1
González-Vallejo, AG1
Hernandez-López, E1
Carrión Sari, SK1
Lezaun, A1
Colas Sanz, C1
Selmanoglu, A1
Güvenir, H1
Celik, IK1
Karaatmaca, B1
Toyran, M1
Civelek, E1
Misirlioglu, ED1
Bahar, E1
Yoon, H1
Maxey-Jones, CL1
Palmerton, A1
Farmer, JR1
Bateman, BT1
Elkoundi, A1
Bensghir, M1
Lalaoui, SJ1
Bina, B1
Hersh, EV1
Hilario, M1
Alvarez, K1
McLaughlin, B1
Hermann, R1
Lam, F1
Spackman, G1
Kvisselgaard, AD1
Melchiors, BB1
Krøigaard, M1
Garvey, LH1
Sanan, N1
Lee, J1
Baxter, C1
Jeskey, J1
Hostoffer, R1
Dyer, JE1
Nafie, S1
Mellon, JK1
Khan, MA1
To, D1
Kossintseva, I1
de Gannes, G1
Nishi, M1
Zen, K1
Kambayashi, D1
Asada, S1
Yamaguchi, S1
Tatsukawa, H1
Thompson, TM1
Theobald, JL1
Rajalakshmi, AR1
Kumar, MA1
King, G1
Byrne, A1
Fleming, P1
Yamaguchi, T1
Nakagome, K1
Udagawa, K1
Takaku, Y1
Sato, N1
Soma, T1
Hagiwara, K1
Kanazawa, M1
Nagata, M1
Hu, WL1
Chang, CH1
Hung, YC1
Shieh, TY1
Tanboğa, IH1
Karabay, CY1
Can, MM1
Akgün, T1
Güler, A1
Turkylmaz, E1
Ozveren, O1
Kaymaz, C1
Sambrook, PJ1
Smith, W1
Elijah, J1
Goss, AN1
Kluger, N1
Raison-Peyron, N1
Michot, C1
Guillot, B1
Bessis, D1
Glück, J1
Rymarczyk, B1
Rogala, B1
Kamata, M1
Tada, Y1
Yazawa, N1
Watanabe, T1
Kikuchi, K1
Sato, S1
Becker, DE1
Reed, KL1
Kartal, O1
Gulec, M1
Caliskaner, AZ1
Sener, O1
Evans, LA1
Pointing, J1
Wills, EJ1
Michalopoulos, J1
Adelstein, S1
Knowles, SR1
Uetrecht, JP1
Shear, NH1
Hawkins, JM1
Moore, PA1
Helfman, M1
Mackley, CL1
Marks, JG1
Anderson, BE1
Calman, C1
Cox, B1
Durieux, ME1
Marcus, MA1
Kaufmann, JM1
Hale, EK1
Ashinoff, RA1
Cohen, DE1
CERCIELLO, G1
RAJKA, G2
SKOG, E1
NAGOSHI, Y1
KANEKO, Z1
UMEZAWA, S1
MICHINOSHITA, K1
YAMAMOTO, K1
NAKAI, Y1
FUKUDA, S1
AOKI, S1
MIYABE, I1
SUGIYAMA, S1
HONJO, S1
YAMADA, T1
KIMURA, S1
NAKAZAWA, A1
FURUYA, M1
HOSOGAWA, A1
KOBAYASHI, Y1
MEYER, RA1
JAKUBOWSKI, W1
CAMPOLATTARO, JP1
HAROLDSON, JH1
WELBORN, JF1
KANE, JP1
ANSELL, G1
ANSELL, A1
PERKINS, HM1
Berkun, Y1
Ben-Zvi, A1
Levy, Y1
Galili, D1
Shalit, M1
Lange, G1
Venter, EK1
Meyer, BJ1
Parker, JF1
Vats, A1
Bauer, G1
Amsler, E1
Flahault, A1
Mathelier-Fusade, P1
Aractingi, S1
Quhill, F1
Bowling, B1
Packard, RB1
Suzuki, J1
Nikko, H1
Kaiho, F1
Yamaguchi, K1
Wada, H1
Suzuki, M1
Acharya, D1
Kohase, H1
Umino, M1
Dance, D1
Basti, S1
Koch, DD1
Patil, B1
Agius-Fernandez, A1
Worstmann, T1
Ng, JM1
Villeneuve, V1
Kaufman, I1
Weeks, S1
Deschamps, A1
Komericki, P1
Arbab, E1
Grims, R1
Kränke, B1
Aberer, W1
Levy, J1
Lifshitz, T1
Noormalin, A1
Shahnaz, M1
Rosmilah, M1
Mujahid, SH1
Gendeh, BS1
Parkinson, J1
Tremblay, F1
Haugen, RN1
Brown, CW1
Gottlieb, SJ1
Falliers, CJ1
Fardon, DF1
Tamura, T1
Duff, HJ1
Roden, DM1
Marney, S1
Colley, DG1
Maffucci, R1
Primm, RK1
Oates, JA1
Woosley, RL1
Lederman, DA1
Freedman, PD1
Kerpel, SM1
Lumerman, H1
Metzner, HH1
Braun, G1
Wahl, G1
Sekiguchi, M1
Kamiura, M1
Iinuma, M1
Ito, K1
Baba, H1
Asakura, T1
Maeda, M1
Brubnjak-Jevtic, V1
Swanson, JG2
Barer, MR1
McAllen, MK1
Wildsmith, JA1
Gill, C1
Michaelides, PL1
Babajews, AV1
Ivanyi, L1
Srivastava, VK1
Nath, C1
Srivastava, M1
Pape, LA1
Dry, J1
Leynadier, F1
Chin, TM1
Fellner, MJ1
Mulvey, PM1
Jackson, D1
Chen, AH1
Bennett, CR1
Thakur, BK1
Murali, MR1
Dire, DJ1
Hogan, DE1
Hodgson, TA1
Shirlaw, PJ1
Challacombe, SJ1
Green, SM1
Whalen, JD1
Dufresne, RG1
Goswamy, R1
Prabhudesai, P1
Chaudhuri, A1
Mahashur, AA1
Vaidyanathan, S1
Krishnan, KR1
Soni, BM1
Fraser, MH1
Zanni, MP3
von Greyerz, S3
Schnyder, B3
Mauri-Hellweg, D1
Brander, C1
Kalbermatten, C1
Pichler, WJ3
Fader, DJ1
Johnson, TM1
Cuesta-Herranz, J1
de las Heras, M1
Fernández, M1
Lluch, M1
Figueredo, E1
Umpierrez, A1
Lahoz, C1
Gourrier, E1
Karoubi, P1
el Hanache, A1
Merbouche, S1
Mouchnino, G1
Leraillez, J1
Selcuk, E1
Ertürk, S1
Afrashi, A1
Meechan, J1
Wendland, T1
Bartfield, JM1
Jandreau, SW1
Raccio-Robak, N1
Ezsias, A2
Hari, Y1
Walters, G1
Georgiou, T1
Hayward, JM1
Ball, IA1
Bircher, AJ1
Surber, C1
Dilraj, A1
Cutts, FT1
Bennett, JV1
Coovadia, HM1
Lorette, G1
Kakuyama, M1
Toda, H1
Osawa, M1
Fukuda, K1
Zuberi, BF1
Shaikh, MR1
Jatoi, NU1
Shaikh, WM1
Rood, JP2
Scala, E1
Giani, M1
Pirrotta, L1
Guerra, EC1
Girardelli, CR1
De Pità, O1
Puddu, P1
Kalghatgi, S1
Campbell, JR1
Maestrello, CL1
Campbell, RL1
Simon, E1
Matee, M1
Browne, IM1
Birnbach, DJ1
Cetinkaya, F1
Brown, RS1
Paluvoi, S1
Choksi, S1
Burgess, CM1
Reece, ER1
Sabbah, A2
Hoffmann, H1
Maibach, HI1
Prout, E1
Luebke, NH1
Walker, JA1
Aldrete, JA4
Cass, N1
Dosseh, MB1
Dupiot, M1
Guèye, MS1
Goldberg, RT1
Wightman, MA1
Vaughan, RW1
Verrill, PJ1
Grimes, DA1
Cates, W1
Ravindranathan, N1
Poraszka, J1
Szeluga, J1
Stofer, AR1
Ulrich, L1
Steinsiepe, KF1
Egger, G1
Narang, R1
Dunoyer-Geindre, S1
Ludi, F1
Perez, T1
Terki, N1
Gumowski, PI1
Girard, JP1
Klein, CE1
Gall, H1
Kurashima, K1
Ogawa, H1
Namura, M1
Kanaya, N1
Oya, T1
Hayashi, M1
Fujimura, M1
Matsuda, T1
Ahmad, S1
Fisher, DA1
Grothe, DR1
Sunderland, T1
Vitiello, B1
Martinez, R1
Harris, P1
Le Sellin, J1
Drouet, M1
Bonneau, JC1
Dooms-Goossens, A1
de Alam, AG1
Degreef, H1
Kochuyt, A1
Dunn, JM1
Groth, PE1
DeSimone, A1
Tucker, LE1
Ruffles, SP1
Gayres, JG1
Levy, SM1
Baker, KA1
Chandler, MJ1
Grammer, LC1
Patterson, R1
Miyake, T1
Kawamori, J1
Yoshida, T1
Ivey, DF1
Müller, U1
Bircher, A1
Bischof, M1
Falace, DA1
Hill, JS1
Kennedy, KS1
Cave, RH1
Eyre, J1
Nally, FF1
Lehner, T1
Wetherall, JD1
Hackshaw, R1
Turner, KJ1
Sehhati, G1
Frey, R1
Mildner, R1
Smith, RB1
Everett, WG1
Shields, PW2
Divinyi, T1
Gyulavári, O1
Alföldy, G1
Harris, R1
Brown, LL1
Covino, BG1
Fink, BR1
Reinisch, J1
Myers, B1
Judit, BS1
Sandmire, HF1
Austin, SD1
Farber, HI1
Oelschläger, H1
Nieschulz, O1
Meyer, F1
Schulz, KH1
Finsterbush, A1
Stein, H1
Robin, GC1
Geller, R1
Cotev, S1
Woldorf, NM1
Pastore, PN1
Collan, Y1
Servo, C1
Winblad, I1
O'Higgins, JW1
Geddes, IC1
Waldman, HB1
Binkley, G1
Wellins, SL1
Terai, Y1
Tamagawa, K1
Kojima, M1
Gruszecka, M1
Kralisz, W1
Todd, DP1
Bartsch, R1
Graupner, K1
Walker, RT1
Jedrzejewska, A1
Lynas, RF1
Munsey, WF1
Kopp, WL1

Clinical Trials (12)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy and Safety of Prilocaine 2% and Lidocaine 5% Hyperbaric Against Spinal Anesthesia in Post Cystoscopy Procedure[NCT05834647]Phase 445 participants (Anticipated)Interventional2023-08-01Not yet recruiting
Effects of Continuous Lidocaine Infusion Via Closed Chest Drainage Tube on Postoperative Analgesia for Patients Undergoing Thoracoscopic Partial Lung Resection: a Single-center Randomized Controlled Clinical Trial[NCT05901389]456 participants (Anticipated)Interventional2023-06-30Not yet recruiting
Efficacy of Postoperative Pain Control Between Transarticular VS Periartiucular Multimodal Drug Infiltration in Total Hip Arthroplasty: Double-blinded Randomized Control Trial[NCT05325671]120 participants (Anticipated)Interventional2022-04-05Not yet recruiting
The Comparison Between Dexamethasone and Morphine as an Adjuvant to Epidural Bupivacaine for Post-operative Analgesia in Lower Extremity Surgery[NCT03051022]64 participants (Actual)Interventional2016-05-01Completed
Comparative Study of the Anaesthetic Efficacy of 4% Articaine Versus 2% Mepivacaine in Mandibular Third Molar Germectomy Using Different Anaesthetic Techniques: a Split-mouth Clinical Trial[NCT04465149]50 participants (Actual)Interventional2018-06-30Completed
Clinical Evaluation of Arrhythmia Mapping With a Globe-Shaped, High-Density, Multi-Electrode Mapping Catheter[NCT05373862]40 participants (Actual)Interventional2022-07-29Completed
Clinical Evaluation of Arrhythmia Mapping With the Multi-Electrode OPTRELL™ Mapping Catheter[NCT04983797]31 participants (Actual)Interventional2021-08-25Completed
Clinical Evaluation of Intracardiac Ultrasound With the NUVISION NAV Ultrasound Catheter[NCT05970120]30 participants (Anticipated)Interventional2023-09-05Recruiting
Maternal-Fetal Monitoring of Patients With Rheumatic Heart Disease During Dental Procedure Under Local Anesthesia[NCT00482573]Phase 131 participants (Actual)Interventional2004-04-30Completed
Antipruritic Effect of Topical Ketamine, Amitriptyline, and Lidocaine[NCT03096444]Phase 213 participants (Actual)Interventional2017-05-23Terminated (stopped due to Efficacy was not seen after interim analysis)
Assessing the Effect of Paracervical Block Volume on Pain Control for Dilation and Curettage: a Randomized Controlled Trial[NCT03636451]Phase 3114 participants (Actual)Interventional2018-10-29Completed
An Evaluation of the Paracervical Block for Pain Control in First Trimester Surgical Abortion[NCT01094366]Phase 4121 participants (Actual)Interventional2010-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants With Non-serious Adverse Events Within 7 Days of Index Procedure Associated With the Use of the OPTRELL Catheter

Number of participants with non-serious adverse events within 7 days of index procedure associated with the use of the OPTRELL catheter were reported. An AE is any untoward medical occurrence in a participant participating in a clinical study that does not necessarily have a causal relationship with the pharmaceutical/biological agent under study. (NCT04983797)
Timeframe: Up to 7 days of index procedure at Day 0

InterventionParticipants (Count of Participants)
OPTRELL Mapping Catheter0

Number of Participants With Pre-ablation Mapping and Clinically Indicated Mapping Performed With the OPTRELL Catheter Without Resort to Other Mapping Catheters

Number of participants with pre-ablation mapping and clinically indicated mapping performed with the OPTRELL catheter without resort to other mapping catheters were reported. (NCT04983797)
Timeframe: Up to 72 days

InterventionParticipants (Count of Participants)
OPTRELL Mapping Catheter31

Number of Participants With SAEs Within 7 Days of Index Procedure

Number of participants with SAEs within 7 days of index procedure were reported. An AE is any untoward medical occurrence in a participant whether or not related to the investigational device. SAE is any AE that results in: death, persistent or significant disability/incapacity, requires inpatient hospitalization or prolongation of existing hospitalization, is life-threatening experience, is a congenital anomaly/birth defect and may jeopardize participant and/or may require medical or surgical intervention to prevent one of the outcomes listed above. (NCT04983797)
Timeframe: Up to 7 days of index procedure at Day 0

InterventionParticipants (Count of Participants)
OPTRELL Mapping Catheter3

Number of Participants With Serious Adverse Events (SAEs) Within 7 Days of Index Procedure Related to the OPTRELL Catheter

Number of participants with SAEs within 7 days of index procedure related to the OPTRELL catheter were reported. An adverse event (AE) is any untoward medical occurrence in a participant whether or not related to the investigational device. SAE is any AE that results in: death, persistent or significant disability/incapacity, requires inpatient hospitalization or prolongation of existing hospitalization, is life-threatening experience, is a congenital anomaly/birth defect and may jeopardize participant and/or may require medical or surgical intervention to prevent one of the outcomes listed above. (NCT04983797)
Timeframe: Up to 7 days of index procedure at Day 0

InterventionParticipants (Count of Participants)
OPTRELL Mapping Catheter0

Number of Responders for Physician Assessment for Ability to Characterize the Tissue

Number of responders for physician assessment for ability to characterize the tissue were reported. A post-procedure survey of 11 questions, each with individual sub-questions were asked. Each question/sub-question was answered by the physician using a Likert scale of 1 to 7 (1=poor and 7=excellent). Responders refers to participants with physician assessment for ability to characterize the tissue. (NCT04983797)
Timeframe: Up to 72 days

InterventionParticipants (Count of Participants)
Compared to the PENTARAY catheter?: Score 1Compared to the PENTARAY catheter?: Score 2Compared to the PENTARAY catheter?: Score 3Compared to the PENTARAY catheter?: Score 4Compared to the PENTARAY catheter?: Score 5Compared to the PENTARAY catheter?: Score 6Compared to the PENTARAY catheter?: Score 7Compared to other competitive multielectrode catheters?: Score 1Compared to other competitive multielectrode catheters?: Score 2Compared to other competitive multielectrode catheters?: Score 3Compared to other competitive multielectrode catheters?: Score 4Compared to other competitive multielectrode catheters?: Score 5Compared to other competitive multielectrode catheters?: Score 6Compared to other competitive multielectrode catheters?: Score 7
OPTRELL Mapping Catheter00000161500000250

Number of Responders for Physician Assessment for Arrhythmogenicity

Number of responders with physician assessment for arrhythmogenicity were reported. A post-procedure survey of 11 questions, each with individual sub-questions were asked. Each question/sub-question was answered by the physician using a Likert scale of 1 to 7 (1=poor and 7=excellent). Responders refers to participants with physician assessment for arrhythmogenicity. (NCT04983797)
Timeframe: Up to 72 days

InterventionParticipants (Count of Participants)
Compared to the PENTARAY catheter?: Score 1Compared to the PENTARAY catheter?: Score 2Compared to the PENTARAY catheter?: Score 3Compared to the PENTARAY catheter?: Score 4Compared to the PENTARAY catheter?: Score 5Compared to the PENTARAY catheter?: Score 6Compared to the PENTARAY catheter?: Score 7Compared to other competitive multielectrode catheters?: Score 1Compared to other competitive multielectrode catheters?: Score 2Compared to other competitive multielectrode catheters?: Score 3Compared to other competitive multielectrode catheters?: Score 4Compared to other competitive multielectrode catheters?: Score 5Compared to other competitive multielectrode catheters?: Score 6Compared to other competitive multielectrode catheters?: Score 7
OPTRELL Mapping Catheter00025101400005191

Number of Responders for Physician Assessment for Catheter Design in OPTRELL Catheter for Mapping

Number of responders for physician assessment for catheter design were reported. A post-procedure survey of 11 questions, each with individual sub-questions were asked. Each question/sub-question was answered by the physician using a Likert scale of 1 to 7 (1=poor and 7=excellent). Responders refers to participants with physician assessment for catheter design in OPTRELL catheter for mapping. (NCT04983797)
Timeframe: Up to 72 days

InterventionParticipants (Count of Participants)
Ability to achieve electrode contact with cardiac tissue: Score 1Ability to achieve electrode contact with cardiac tissue: Score 2Ability to achieve electrode contact with cardiac tissue: Score 3Ability to achieve electrode contact with cardiac tissue: Score 4Ability to achieve electrode contact with cardiac tissue: Score 5Ability to achieve electrode contact with cardiac tissue: Score 6Ability to achieve electrode contact with cardiac tissue: Score 7Electrodes spacing: Score 1Electrodes spacing: Score 2Electrodes spacing: Score 3Electrodes spacing: Score 4Electrodes spacing: Score 5Electrodes spacing: Score 6Electrodes spacing: Score 7Electrode array coverage: Score 1Electrode array coverage: Score 2Electrode array coverage: Score 3Electrode array coverage: Score 4Electrode array coverage: Score 5Electrode array coverage: Score 6Electrode array coverage: Score 7
OPTRELL Mapping Catheter0102218801000131701000921

Number of Responders for Physician Assessment for Catheter Visualization

Number of responders for physician assessment for catheter visualization were reported. A post-procedure survey of 11 questions, each with individual sub-questions were asked. Each question/sub-question was answered by the physician using a Likert scale of 1 to 7 (1=poor and 7=excellent). Responders refers to participants with physician assessment for catheter visualization. (NCT04983797)
Timeframe: Up to 72 days

InterventionParticipants (Count of Participants)
Visualization under fluoroscopy: Score 1Visualization under fluoroscopy: Score 2Visualization under fluoroscopy: Score 3Visualization under fluoroscopy: Score 4Visualization under fluoroscopy: Score 5Visualization under fluoroscopy: Score 6Visualization under fluoroscopy: Score 7Visualization in CARTO 3: Score 1Visualization in CARTO 3: Score 2Visualization in CARTO 3: Score 3Visualization in CARTO 3: Score 4Visualization in CARTO 3: Score 5Visualization in CARTO 3: Score 6Visualization in CARTO 3: Score 7
OPTRELL Mapping Catheter00007915000031018

Number of Responders for Physician Assessment for Catheters Interactions

Number of responders for physician assessment for catheters interactions were reported. A post-procedure survey of 11 questions, each with individual sub-questions were asked. Each question/sub-question was answered by the physician using a Likert scale of 1 to 7 (1=poor and 7=excellent). Responders refers to participants with physician assessment for catheters interactions. (NCT04983797)
Timeframe: Up to 72 days

InterventionParticipants (Count of Participants)
With CARTO 3 System: Score 1With CARTO 3 System: Score 2With CARTO 3 System: Score 3With CARTO 3 System: Score 4With CARTO 3 System: Score 5With CARTO 3 System: Score 6With CARTO 3 System: Score 7EP Lab recording equipment: Score 1EP Lab recording equipment: Score 2EP Lab recording equipment: Score 3EP Lab recording equipment: Score 4EP Lab recording equipment: Score 5EP Lab recording equipment: Score 6EP Lab recording equipment: Score 7Pacing equipment: Score 1Pacing equipment: Score 2Pacing equipment: Score 3Pacing equipment: Score 4Pacing equipment: Score 5Pacing equipment: Score 6Pacing equipment: Score 7Introducer tool on catheter: Score 1Introducer tool on catheter: Score 2Introducer tool on catheter: Score 3Introducer tool on catheter: Score 4Introducer tool on catheter: Score 5Introducer tool on catheter: Score 6Introducer tool on catheter: Score 7Sheath: Score 1Sheath: Score 2Sheath: Score 3Sheath: Score 4Sheath: Score 5Sheath: Score 6Sheath: Score 7Irrigation bag and tubing: Score 1Irrigation bag and tubing: Score 2Irrigation bag and tubing: Score 3Irrigation bag and tubing: Score 4Irrigation bag and tubing: Score 5Irrigation bag and tubing: Score 6Irrigation bag and tubing: Score 7ICD or other implantable devices: Score 1ICD or other implantable devices: Score 2ICD or other implantable devices: Score 3ICD or other implantable devices: Score 4ICD or other implantable devices: Score 5ICD or other implantable devices: Score 6ICD or other implantable devices: Score 7
OPTRELL Mapping Catheter000041215000181210000043700036148000361480000515110001223

Number of Responders for Physician Assessment for Design and Coverage for Confirming PVI

Number of responders for physician assessment for design and coverage for confirming PVI were reported. A post-procedure survey of 11 questions, each with individual sub-questions were asked. Each question/sub-question was answered by the physician using a Likert scale of 1 to 7 (1=poor and 7=excellent). Responders refers to participants with physician assessment for design and coverage for confirming PVI. (NCT04983797)
Timeframe: Up to 72 days

InterventionParticipants (Count of Participants)
Compared to the PENTARAY catheter?: Score 1Compared to the PENTARAY catheter?: Score 2Compared to the PENTARAY catheter?: Score 3Compared to the PENTARAY catheter?: Score 4Compared to the PENTARAY catheter?: Score 5Compared to the PENTARAY catheter?: Score 6Compared to the PENTARAY catheter?: Score 7Compared to other competitive multielectrode catheters?: Score 1Compared to other competitive multielectrode catheters?: Score 2Compared to other competitive multielectrode catheters?: Score 3Compared to other competitive multielectrode catheters?: Score 4Compared to other competitive multielectrode catheters?: Score 5Compared to other competitive multielectrode catheters?: Score 6Compared to other competitive multielectrode catheters?: Score 7
OPTRELL Mapping Catheter000327900040134

Number of Responders for Physician Assessment for Maneuverability & Handling

Number of responders for physician assessment for maneuverability & handling were reported. A post-procedure survey of 11 questions, each with individual sub-questions were asked. Each question/sub-question was answered by the physician using a Likert scale of 1 to 7 (1=poor and 7=excellent). Responders refers to participants with physician assessment for maneuverability & handling. (NCT04983797)
Timeframe: Up to 72 days

InterventionParticipants (Count of Participants)
Ability to Deploy (Left Atrium): Score 1Ability to Deploy (Left Atrium): Score 2Ability to Deploy (Left Atrium): Score 3Ability to Deploy (Left Atrium): Score 4Ability to Deploy (Left Atrium): Score 5Ability to Deploy (Left Atrium): Score 6Ability to Deploy (Left Atrium): Score 7Ability to Deploy (Right Atrium): Score 1Ability to Deploy (Right Atrium): Score 2Ability to Deploy (Right Atrium): Score 3Ability to Deploy (Right Atrium): Score 4Ability to Deploy (Right Atrium): Score 5Ability to Deploy (Right Atrium): Score 6Ability to Deploy (Right Atrium): Score 7Ability to Deploy (Left Ventricle): Score 1Ability to Deploy (Left Ventricle): Score 2Ability to Deploy (Left Ventricle): Score 3Ability to Deploy (Left Ventricle): Score 4Ability to Deploy (Left Ventricle): Score 5Ability to Deploy (Left Ventricle): Score 6Ability to Deploy (Left Ventricle): Score 7Ability to Deploy (Right Ventricle): Score 1Ability to Deploy (Right Ventricle): Score 2Ability to Deploy (Right Ventricle): Score 3Ability to Deploy (Right Ventricle): Score 4Ability to Deploy (Right Ventricle): Score 5Ability to Deploy (Right Ventricle): Score 6Ability to Deploy (Right Ventricle): Score 7Ability to Maneuver (Left Atrium): Score 1Ability to Maneuver (Left Atrium): Score 2Ability to Maneuver (Left Atrium): Score 3Ability to Maneuver (Left Atrium): Score 4Ability to Maneuver (Left Atrium): Score 5Ability to Maneuver (Left Atrium): Score 6Ability to Maneuver (Left Atrium): Score 7Ability to Maneuver (Right Atrium): Score 1Ability to Maneuver (Right Atrium): Score 2Ability to Maneuver (Right Atrium): Score 3Ability to Maneuver (Right Atrium): Score 4Ability to Maneuver (Right Atrium): Score 5Ability to Maneuver (Right Atrium): Score 6Ability to Maneuver (Right Atrium): Score 7Ability to Maneuver (Left Ventricle): Score 1Ability to Maneuver (Left Ventricle): Score 2Ability to Maneuver (Left Ventricle): Score 3Ability to Maneuver (Left Ventricle): Score 4Ability to Maneuver (Left Ventricle): Score 5Ability to Maneuver (Left Ventricle): Score 6Ability to Maneuver (Left Ventricle): Score 7Ability to Maneuver (Right Ventricle): Score 1Ability to Maneuver (Right Ventricle): Score 2Ability to Maneuver (Right Ventricle): Score 3Ability to Maneuver (Right Ventricle): Score 4Ability to Maneuver (Right Ventricles): Score 5Ability to Maneuver (Right Ventricle): Score 6Ability to Maneuver (Right Ventricle): Score 7Ability to Reach Areas (Left Atrium): Score 1Ability to Reach Areas (Left Atrium): Score 2Ability to Reach Areas (Left Atrium): Score 3Ability to Reach Areas (Left Atrium): Score 4Ability to Reach Areas (Left Atrium): Score 5Ability to Reach Areas (Left Atrium): Score 6Ability to Reach Areas (Left Atrium): Score 7Ability to Reach Areas (Right Atrium): Score 1Ability to Reach Areas (Right Atrium): Score 2Ability to Reach Areas (Right Atrium): Score 3Ability to Reach Areas (Right Atrium): Score 4Ability to Reach Areas (Right Atrium): Score 5Ability to Reach Areas (Right Atrium): Score 6Ability to Reach Areas (Right Atrium): Score 7Ability to Reach Areas (Left Ventricle): Score 1Ability to Reach Areas (Left Ventricle): Score 2Ability to Reach Areas (Left Ventricle): Score 3Ability to Reach Areas (Left Ventricle): Score 4Ability to Reach Areas (Left Ventricle): Score 5Ability to Reach Areas (Left Ventricle): Score 6Ability to Reach Areas (Left Ventricle): Score 7Ability to Reach Areas (Right Ventricle): Score 1Ability to Reach Areas (Right Ventricle): Score 2Ability to Reach Areas (Right Ventricle): Score 3Ability to Reach Areas (Right Ventricle): Score 4Ability to Reach Areas (Right Ventricle): Score 5Ability to Reach Areas (Right Ventricle): Score 6Ability to Reach Areas (Right Ventricle): Score 7Ability to Withdraw (Left Atrium): Score 1Ability to Withdraw (Left Atrium): Score 2Ability to Withdraw (Left Atrium): Score 3Ability to Withdraw (Left Atrium): Score 4Ability to Withdraw (Left Atrium): Score 5Ability to Withdraw (Left Atrium): Score 6Ability to Withdraw (Left Atrium): Score 7Ability to Withdraw (Right Atrium): Score 1Ability to Withdraw (Right Atrium): Score 2Ability to Withdraw (Right Atrium): Score 3Ability to Withdraw (Right Atrium): Score 4Ability to Withdraw (Right Atrium): Score 5Ability to Withdraw (Right Atrium): Score 6Ability to Withdraw (Right Atrium): Score 7Ability to Withdraw (Left Ventricle): Score 1Ability to Withdraw (Left Ventricle): Score 2Ability to Withdraw (Left Ventricle): Score 3Ability to Withdraw (Left Ventricle): Score 4Ability to Withdraw (Left Ventricle): Score 5Ability to Withdraw (Left Ventricle): Score 6Ability to Withdraw (Left Ventricle): Score 7Ability to Withdraw (Right Ventricle): Score 1Ability to Withdraw (Right Ventricle): Score 2Ability to Withdraw (Right Ventricle): Score 3Ability to Withdraw (Right Ventricle): Score 4Ability to Withdraw (Right Ventricle): Score 5Ability to Withdraw (Right Ventricle): Score 6Ability to Withdraw (Right Ventricle): Score 7Insertion/ Withdrawal from Introducer Sheath: Score 1Insertion/ Withdrawal from Introducer Sheath: Score 2Insertion/ Withdrawal from Introducer Sheath: Score 3Insertion/ Withdrawal from Introducer Sheath: Score 4Insertion/ Withdrawal from Introducer Sheath: Score 5Insertion/ Withdrawal from Introducer Sheath: Score 6Insertion/ Withdrawal from Introducer Sheath: Score 7Learning Curve: Score 1Learning Curve: Score 2Learning Curve: Score 3Learning Curve: Score 4Learning Curve: Score 5Learning Curve: Score 6Learning Curve: Score 7
OPTRELL Mapping Catheter00000617000003300031500001000000077900001140005040001000000023126000021300132300001000000008150000042000225000000100012991000044185

Number of Responders for Physician Assessment for Pacing

Number of responders for physician assessment for pacing (local pacing capture) were reported. A post-procedure survey of 11 questions, each with individual sub-questions were asked. Each question/sub-question was answered by the physician using a Likert scale of 1 to 7 (1=poor and 7=excellent). Responders refers to participants with physician assessment for pacing. (NCT04983797)
Timeframe: Up to 72 days

InterventionParticipants (Count of Participants)
Local pacing capture: Score 1Local pacing capture: Score 2Local pacing capture: Score 3Local pacing capture: Score 4Local pacing capture: Score 5Local pacing capture: Score 6Local pacing capture: Score 7
OPTRELL Mapping Catheter0011223

Number of Responders for Physician Assessment for Signal Collection and Quality

Number of responders for physician assessment for signal collection and quality were reported. A post-procedure survey of 11 questions, each with individual sub-questions were asked. Each question/sub-question was answered by the physician using a Likert scale of 1 to 7 (1=poor and 7=excellent). Responders refers to participants with physician assessment for signal collection and quality (NCT04983797)
Timeframe: Up to 72 days

InterventionParticipants (Count of Participants)
UNIPOLAR signals in Atrium: Score 1UNIPOLAR signals in Atrium: Score 2UNIPOLAR signals in Atrium: Score 3UNIPOLAR signals in Atrium: Score 4UNIPOLAR signals in Atrium: Score 5UNIPOLAR signals in Atrium: Score 6UNIPOLAR signals in Atrium: Score 7UNIPOLAR signals in Ventricle: Score 1UNIPOLAR signals in Ventricle: Score 2UNIPOLAR signals in Ventricle: Score 3UNIPOLAR signals in Ventricle: Score 4UNIPOLAR signals in Ventricle: Score 5UNIPOLAR signals in Ventricle: Score 6UNIPOLAR signals in Ventricle: Score 7UNIPOLAR noise encountered: Score 1UNIPOLAR noise encountered: Score 2UNIPOLAR noise encountered: Score 3UNIPOLAR noise encountered: Score 4UNIPOLAR noise encountered: Score 5UNIPOLAR noise encountered: Score 6UNIPOLAR noise encountered: Score 7BIPOLAR signals in Atrium: Score 1BIPOLAR signals in Atrium: Score 2BIPOLAR signals in Atrium: Score 3BIPOLAR signals in Atrium: Score 4BIPOLAR signals in Atrium: Score 5BIPOLAR signals in Atrium: Score 6BIPOLAR signals in Atrium: Score 7BIPOLAR signals in Ventricle: Score 1BIPOLAR signals in Ventricle: Score 2BIPOLAR signals in Ventricle: Score 3BIPOLAR signals in Ventricle: Score 4BIPOLAR signals in Ventricle: Score 5BIPOLAR signals in Ventricle: Score 6BIPOLAR signals in Ventricle: Score 7BIPOLAR noise encountered: Score 1BIPOLAR noise encountered: Score 2BIPOLAR noise encountered: Score 3BIPOLAR noise encountered: Score 4BIPOLAR noise encountered: Score 5BIPOLAR noise encountered: Score 6BIPOLAR noise encountered: Score 7
OPTRELL Mapping Catheter000014200013400001474000007160000171000131215

Number of Responders for Physician Assessment for Workflow

Number of responders for physician assessment for workflow were reported. A post-procedure survey of 11 questions, each with individual sub-questions were asked. Each question/sub-question was answered by the physician using a Likert scale of 1 to 7 (1=poor and 7=excellent). Responders refers to participants with physician assessment for workflow. (NCT04983797)
Timeframe: Up to 72 days

InterventionParticipants (Count of Participants)
Ability to reduce fluoroscopy: Score 1Ability to reduce fluoroscopy: Score 2Ability to reduce fluoroscopy: Score 3Ability to reduce fluoroscopy: Score 4Ability to reduce fluoroscopy: Score 5Ability to reduce fluoroscopy: Score 6Ability to reduce fluoroscopy: Score 7Time for pre-procedure mapping: Score 1Time for pre-procedure mapping: Score 2Time for pre-procedure mapping: Score 3Time for pre-procedure mapping: Score 4Time for pre-procedure mapping: Score 5Time for pre-procedure mapping: Score 6Time for pre-procedure mapping: Score 7Time for post-procedure mapping after standard of care ablation: Score 1Time for post-procedure mapping after standard of care ablation: Score 2Time for post-procedure mapping after standard of care ablation: Score 3Time for post-procedure mapping after standard of care ablation: Score 4Time for post-procedure mapping after standard of care ablation: Score 5Time for post-procedure mapping after standard of care ablation: Score 6Time for post-procedure mapping after standard of care ablation: Score 7Ability to identify targets: Score 1Ability to identify targets: Score 2Ability to identify targets: Score 3Ability to identify targets: Score 4Ability to identify targets: Score 5Ability to identify targets: Score 6Ability to identify targets: Score 7
OPTRELL Mapping Catheter000106105000841090002499000101314

Peak Itch Intensity Between the Vehicle and Active Treatments (Individual and KeAmLi-combo).

"Peak itch intensity between the vehicle and 4 other active treatments (individual ketamine, amitriptyline, or lidocaine, and KeAmLi-combo). Itch intensity was measured on a 100mm scale visual analog scale for 10 minutes. 0 was weighted with no itch and 100 was weighted with most itch imaginable." (NCT03096444)
Timeframe: 10 minutes

InterventionIntensity score (Mean)
Topical KeAmLi Combo62.7
Topical Ketamine63.1
Topical Amitriptyline69.2
Topical Lidocaine65.8
Topical Vehicle61.9

Mechanical Thresholds (Mechanical Detection and Pain).

Assess mechanical detection and pain thresholds using von Frey filaments stimulators (measured in force mN) to calculate the final threshold as the geometric mean of five series of ascending and descending stimuli. (NCT03096444)
Timeframe: 5 minutes

,,,,
InterventionmN (Mean)
Mechanical Detection ThresholdMechanical Pain Threshold
Topical Amitriptyline3.573423965152.4768146
Topical KeAmLi Combo3.519376956152.3293608
Topical Ketamine3.464204768135.9
Topical Lidocaine3.546037659126.9
Topical Vehicle3.525692637148.7138273

Thermal Threshold Detection (Warmth and Heat Pain)

Two standardized quantitative sensory tests are performed to measure warmth detection threshold (assesses the threshold of which warmth sensation is first detected) and heat pain threshold (assesses the threshold at which heat pain sensation is first detected). Measured in change in celsius. (NCT03096444)
Timeframe: 3 minutes

,,,,
InterventionDegrees celsius (Mean)
Warm Detection ThresholdHeat Pain Threshold
Topical Amitriptyline33.940.0
Topical KeAmLi Combo33.639.8
Topical Ketamine34.040.0
Topical Lidocaine33.739.4
Topical Vehicle33.839.7

Overall Pain

Distance (mm) from the left of the 100-mm Visual Analog Scale (VAS) (reflecting magnitude of pain) recorded after the procedure reflecting the overall pain felt during the procedure. Pain will be assessed using a 100 mm visual analogue scale with the anchors 0 = none, 100 mm = worst imaginable. (NCT03636451)
Timeframe: Once 10 minutes after the procedure on the day of recruitment, approximately one minute.

Interventionunits on a scale (Median)
20cc 1% Lidocaine With 2 Units of Vasopressin Paracervical Block57
40cc Buffered 0.5% Lidocaine With 2 Units of Vasopressin Paracervical Block56

Pain 10 Minutes Post Procedure

Distance (mm) from the left of the 100-mm Visual Analog Scale (VAS) (reflecting magnitude of pain) recorded 10 minutes after the completion of the procedure. Pain will be assessed using a 100 mm visual analogue scale with the anchors 0 = none, 100 mm = worst imaginable. (NCT03636451)
Timeframe: Once 10 minutes after the procedure on the day of recruitment, approximately one minute.

Interventionunits on a scale (Median)
20cc 1% Lidocaine With 2 Units of Vasopressin Paracervical Block26
40cc Buffered 0.5% Lidocaine With 2 Units of Vasopressin Paracervical Block11

Pain With Cervical Dilation

Distance (mm) from the left of the 100-mm Visual Analog Scale (VAS) (reflecting magnitude of pain) recorded at time of cervical dilation. Pain will be assessed using a 100 mm visual analogue scale with the anchors 0 = none, 100 mm = worst imaginable. (NCT03636451)
Timeframe: Once during the procedure on the day of recruitment, approximately one minute. During procedure at time of cervical dilation.

Interventionunits on a scale (Median)
20cc 1% Lidocaine With 2 Units of Vasopressin Paracervical Block52
40cc Buffered 0.5% Lidocaine With 2 Units of Vasopressin Paracervical Block45

Pain With Uterine Aspiration

Distance (mm) from the left of the 100-mm Visual Analog Scale (VAS) (reflecting magnitude of pain) recorded immediately after uterine aspiration. Pain will be assessed using a 100 mm visual analogue scale with the anchors 0 = none, 100 mm = worst imaginable. (NCT03636451)
Timeframe: Once during the procedure on the day of recruitment, approximately 1 minute. During procedure immediately after uterine aspiration.

Interventionunits on a scale (Median)
20cc 1% Lidocaine With 2 Units of Vasopressin Paracervical Block46
40cc Buffered 0.5% Lidocaine With 2 Units of Vasopressin Paracervical Block58

Reviews

12 reviews available for lidocaine and Drug Hypersensitivity

ArticleYear
Lidocaine: A Local Anesthetic, Its Adverse Effects and Management.
    Medicina (Kaunas, Lithuania), 2021, Jul-30, Volume: 57, Issue:8

    Topics: Anesthesia, Local; Anesthetics, Local; Drug Hypersensitivity; Drug-Related Side Effects and Adverse

2021
True Allergy to Amide Local Anesthetics: A Review and Case Presentation.
    Anesthesia progress, 2018,Summer, Volume: 65, Issue:2

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Contraindications, Drug; Diphenhydramine; Drug Hypers

2018
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthetics: review of pharmacological considerations.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Ane

2012
Local anesthesia: advances in agents and techniques.
    Dental clinics of North America, 2002, Volume: 46, Issue:4

    Topics: Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Carticaine; Chemistry, Pharm

2002
Toxicity of local anaesthetics.
    Best practice & research. Clinical anaesthesiology, 2003, Volume: 17, Issue:1

    Topics: Anesthetics, Local; Animals; Bupivacaine; Cardiovascular System; Cocaine; Drug Hypersensitivity; Eti

2003
Toxicity of local anaesthetics.
    Best practice & research. Clinical anaesthesiology, 2003, Volume: 17, Issue:1

    Topics: Anesthetics, Local; Animals; Bupivacaine; Cardiovascular System; Cocaine; Drug Hypersensitivity; Eti

2003
Toxicity of local anaesthetics.
    Best practice & research. Clinical anaesthesiology, 2003, Volume: 17, Issue:1

    Topics: Anesthetics, Local; Animals; Bupivacaine; Cardiovascular System; Cocaine; Drug Hypersensitivity; Eti

2003
Toxicity of local anaesthetics.
    Best practice & research. Clinical anaesthesiology, 2003, Volume: 17, Issue:1

    Topics: Anesthetics, Local; Animals; Bupivacaine; Cardiovascular System; Cocaine; Drug Hypersensitivity; Eti

2003
Toxicity of local anaesthetics.
    Best practice & research. Clinical anaesthesiology, 2003, Volume: 17, Issue:1

    Topics: Anesthetics, Local; Animals; Bupivacaine; Cardiovascular System; Cocaine; Drug Hypersensitivity; Eti

2003
Toxicity of local anaesthetics.
    Best practice & research. Clinical anaesthesiology, 2003, Volume: 17, Issue:1

    Topics: Anesthetics, Local; Animals; Bupivacaine; Cardiovascular System; Cocaine; Drug Hypersensitivity; Eti

2003
Toxicity of local anaesthetics.
    Best practice & research. Clinical anaesthesiology, 2003, Volume: 17, Issue:1

    Topics: Anesthetics, Local; Animals; Bupivacaine; Cardiovascular System; Cocaine; Drug Hypersensitivity; Eti

2003
Toxicity of local anaesthetics.
    Best practice & research. Clinical anaesthesiology, 2003, Volume: 17, Issue:1

    Topics: Anesthetics, Local; Animals; Bupivacaine; Cardiovascular System; Cocaine; Drug Hypersensitivity; Eti

2003
Toxicity of local anaesthetics.
    Best practice & research. Clinical anaesthesiology, 2003, Volume: 17, Issue:1

    Topics: Anesthetics, Local; Animals; Bupivacaine; Cardiovascular System; Cocaine; Drug Hypersensitivity; Eti

2003
What is the role of diphenhydramine in local anesthesia?
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 1996, Volume: 3, Issue:3

    Topics: Anesthesia, Local; Anesthetics, Local; Diphenhydramine; Drug Hypersensitivity; Emergency Medical Ser

1996
Medical issues and emergencies in the dermatology office.
    Journal of the American Academy of Dermatology, 1997, Volume: 36, Issue:1

    Topics: Anaphylaxis; Anesthetics, Local; Anti-Arrhythmia Agents; Anticoagulants; Cerebrovascular Disorders;

1997
An adverse reaction to local anaesthesia: report of a case.
    Dental update, 1996, Volume: 23, Issue:8

    Topics: Adult; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Diagnostic Errors; Drug Hypersensi

1996
Physiology and pharmacology of local anesthetic agents.
    International ophthalmology clinics, 1973,Summer, Volume: 13, Issue:2

    Topics: Administration, Topical; Amides; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular System; Ce

1973
Local anesthesia. 1.
    The New England journal of medicine, 1972, May-04, Volume: 286, Issue:18

    Topics: Action Potentials; Anesthesia, Local; Anesthetics, Local; Animals; Cardiovascular System; Cell Membr

1972
Acute and chronic toxicity of local anaesthetics.
    Canadian Anaesthetists' Society journal, 1973, Volume: 20, Issue:1

    Topics: Anesthesia, Obstetrical; Anesthetics, Local; Animals; Brain; Cats; Diazepam; Drug Hypersensitivity;

1973
[N-(gamma-(4-phenoxymethylphenyl)propyl)-morpholine--a new surface anesthetic of remarkable tolerance. 6. Report on the syntheses of new compounds with local anethetic effect. 1].
    Arzneimittel-Forschung, 1968, Volume: 18, Issue:6

    Topics: Anesthetics, Local; Animals; Anti-Inflammatory Agents; Autonomic Nervous System; Bacteria; Blood Pre

1968

Trials

4 trials available for lidocaine and Drug Hypersensitivity

ArticleYear
Double-blinded comparison of diphenhydramine versus lidocaine as a local anesthetic.
    Annals of emergency medicine, 1993, Volume: 22, Issue:9

    Topics: Adult; Anesthetics, Local; Diphenhydramine; Double-Blind Method; Drug Hypersensitivity; Humans; Inje

1993
Use of EMLA cream in a department of neonatology.
    Pain, 1996, Volume: 68, Issue:2-3

    Topics: Anesthetics, Local; Drug Combinations; Drug Eruptions; Drug Hypersensitivity; Hospital Departments;

1996
Randomized trial of diphenhydramine versus benzyl alcohol with epinephrine as an alternative to lidocaine local anesthesia.
    Annals of emergency medicine, 1998, Volume: 32, Issue:6

    Topics: Adult; Anesthetics, Local; Benzyl Alcohol; Diphenhydramine; Double-Blind Method; Drug Combinations;

1998
Comparison of compounds used for intradermal anesthesia.
    Anesthesiology, 1976, Volume: 45, Issue:6

    Topics: Adult; Anesthesia, Local; Anesthetics, Local; Benzyl Alcohols; Clinical Trials as Topic; Drug Hypers

1976

Other Studies

172 other studies available for lidocaine and Drug Hypersensitivity

ArticleYear
Anaphylactic Shock to Lidocaine: A Rare Case With Evaluation of Cross-Reactivity Between Local Anesthetics.
    Journal of investigational allergology & clinical immunology, 2021, Volume: 31, Issue:5

    Topics: Anaphylaxis; Anesthetics, Local; Cross Reactions; Drug Hypersensitivity; Humans; Lidocaine

2021
[Anafilaxia perioperatoria a sevoflurano, un caso muy raro].
    Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993), 2023, Volume: 70, Issue:4

    Topics: Anaphylaxis; Anesthetics; Child; Drug Hypersensitivity; Epinephrine; Humans; Latex; Lidocaine; Male;

2023
Anaphylaxis due to Perioperative Intravenous Lidocaine.
    Journal of investigational allergology & clinical immunology, 2021, Apr-20, Volume: 31, Issue:2

    Topics: Administration, Intravenous; Aged; Allergens; Anaphylaxis; Anesthesia; Drug Hypersensitivity; Humans

2021
Immediate local anesthetic reactions and diagnostic test results in pediatric patients.
    Allergologia et immunopathologia, 2021, Volume: 49, Issue:3

    Topics: Adolescent; Anesthetics, Local; Child; Child, Preschool; Drug Hypersensitivity; Female; Humans; Hype

2021
Difficult Airway Management Caused by Local Anesthetic Allergy During Emergent Cesarean Delivery: A Case Report.
    A & A case reports, 2017, Aug-01, Volume: 9, Issue:3

    Topics: Adult; Airway Management; Anaphylaxis; Anesthetics, Local; Angioedema; Cesarean Section; Drug Hypers

2017
Nebulized ketamine for successful management of difficult airway.
    Journal of clinical anesthesia, 2017, Volume: 41

    Topics: Abscess; Administration, Inhalation; Adult; Aerosols; Anti-Infective Agents; Bronchoscopes; C-Reacti

2017
CAT of the Month (Critically Appraised Topics): True Allergic Reaction to Amide Local Anesthetics such as Lidocaine is Confirmed by Immunologic Testing (UT CAT# 3062).
    Texas dental journal, 2016, Volume: 133, Issue:11

    Topics: Adult; Amides; Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Hypersensitivity, Delayed;

2016
Lidocaine as a Rare and Hidden Allergen in the Perioperative Setting: A Case Report.
    A&A practice, 2019, Jun-15, Volume: 12, Issue:11

    Topics: Allergens; Drug Hypersensitivity; Drug Interactions; Female; Humans; Lidocaine; Mepivacaine; Middle

2019
Delayed and protracted allergic reaction to oral lidocaine.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2019, Volume: 123, Issue:4

    Topics: Adult; Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Immunoglobulin E; Lidocaine; Skin

2019
Anaphylactic reaction to intraurethral chlorhexidine: sensitisation following previous repeated uneventful administration.
    Annals of the Royal College of Surgeons of England, 2013, Volume: 95, Issue:6

    Topics: Aged, 80 and over; Anaphylaxis; Anti-Infective Agents, Local; Chlorhexidine; Cystoscopy; Drug Combin

2013
Lidocaine contact allergy is becoming more prevalent.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2014, Volume: 40, Issue:12

    Topics: Anesthesia, Local; Benzocaine; British Columbia; Dermatitis, Allergic Contact; Drug Hypersensitivity

2014
Stent dislodgement induced by a vasodilator used for severe coronary artery spasm caused by Kounis syndrome.
    Cardiovascular intervention and therapeutics, 2016, Volume: 31, Issue:1

    Topics: Aged; Anesthetics, Local; Coronary Vasospasm; Device Removal; Drug Hypersensitivity; Foreign-Body Mi

2016
Hoigne syndrome: a little-known adverse effect of lidocaine.
    The American journal of emergency medicine, 2016, Volume: 34, Issue:3

    Topics: Acute Disease; Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Lidocaine; Syndrome; Young

2016
Hyaluronidase hypersensitivity: A rare complication of peribulbar block.
    Indian journal of ophthalmology, 2016, Volume: 64, Issue:2

    Topics: Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Cataract Extraction; Drug Hypersensitivity;

2016
A case of severe NSAID exacerbated respiratory disease (NERD) following a dental procedure in a child.
    European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, 2016, Volume: 17, Issue:4

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Cyclooxygenase 2 Inhibitors; Drug Hyper

2016
[Clinical examination of challenge test to local anesthetics].
    Arerugi = [Allergy], 2009, Volume: 58, Issue:6

    Topics: Adult; Aged; Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Lidocaine; Male; Middle Aged

2009
Acupuncture anesthesia for complicated dental extractions in patients with lidocaine allergy.
    Journal of alternative and complementary medicine (New York, N.Y.), 2009, Volume: 15, Issue:11

    Topics: Acupuncture Analgesia; Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Lidocaine; Middle

2009
Kounis syndrome presenting with cardiogenic shock.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2011, Volume: 12, Issue:11

    Topics: Anaphylaxis; Anesthetics, Local; Coronary Angiography; Coronary Vasospasm; Drug Hypersensitivity; El

2011
Severe adverse reactions to dental local anaesthetics: systemic reactions.
    Australian dental journal, 2011, Volume: 56, Issue:2

    Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Anesthesia, Den

2011
Acute bullous irritant contact dermatitis caused by EMLA® cream.
    Contact dermatitis, 2011, Volume: 65, Issue:3

    Topics: Acute Disease; Anesthetics, Local; Blister; Dermatitis, Irritant; Drug Hypersensitivity; Eczema; Emo

2011
An immediate hypersensitivity reaction caused by tolperisone hydrochloride.
    Journal of investigational allergology & clinical immunology, 2011, Volume: 21, Issue:5

    Topics: Drug Hypersensitivity; Edema; Erythema; Humans; Lidocaine; Male; Middle Aged; Muscle Relaxants, Cent

2011
Drug fever caused by eutectic mixture of local anesthetic cream.
    Journal of investigational allergology & clinical immunology, 2011, Volume: 21, Issue:5

    Topics: Debridement; Drug Hypersensitivity; Drug Interactions; Female; Fever; Humans; Leg Ulcer; Lidocaine;

2011
IgE-mediated reaction to local anaesthetics.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2013, Volume: 23, Issue:2

    Topics: Adult; Anesthesia, Epidural; Anesthetics, Local; Bupivacaine; Cesarean Section; Drug Hypersensitivit

2013
Recurrent facial swelling following dental procedures.
    The Medical journal of Australia, 2002, Nov-04, Volume: 177, Issue:9

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Drug Hypersensitivity; Edema; Face; Humans; Hypersens

2002
Confirming false adverse reactions to drugs by performing individualized, randomized trials.
    The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique, 2002,Fall, Volume: 9, Issue:3

    Topics: Administration, Oral; Adult; Anesthetics, Local; Codeine; Dimenhydrinate; Double-Blind Method; Drug

2002
An unusual symptom of lidocaine allergy. Report of a case.
    The New York state dental journal, 2002, Volume: 68, Issue:10

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Lidocaine; Vis

2002
Delayed-type hypersensitivity to lidocaine.
    Archives of dermatology, 2003, Volume: 139, Issue:3

    Topics: Adult; Aged; Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Hypersensitivity, Delayed; I

2003
Look elsewhere for the culprit.
    The New York state dental journal, 2003, Volume: 69, Issue:2

    Topics: Anesthesia, Dental; Anesthetics, Local; Drug Hypersensitivity; Humans; Lidocaine; Reproducibility of

2003
Cutaneous lidocaine allergy confirmed by patch testing.
    Journal of drugs in dermatology : JDD, 2002, Volume: 1, Issue:2

    Topics: Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Lidocaine; Middle Aged; Patch Tests

2002
[General toxic syndromes caused by local anesthetics].
    Minerva anestesiologica, 1963, Volume: 29

    Topics: Anesthetics; Anesthetics, Local; Cardiovascular Agents; Drug Hypersensitivity; Humans; Lidocaine; Pr

1963
[BRONCHIAL ASTHMA AS A RESULT OF LIDOCAINE ALLERGY].
    Allergie und Asthma, 1963, Volume: 9

    Topics: Asthma; Drug Hypersensitivity; Humans; Lidocaine; Sinusitis; Skin Tests; Surgical Procedures, Operat

1963
[CASES OF SHOCK-LIKE CONDITIONS. (3) CLINICAL CASES OF SHOCK-LIKE CONDITIONS CAUSED BY DRUGS].
    Jibi inkoka Otolaryngology, 1963, Volume: 35

    Topics: Adolescent; Child; Drug Hypersensitivity; Lidocaine; Otolaryngology; Penicillins; Procaine; Shock; S

1963
[CASES OF SHOCK-LIKE CONDITIONS. (6)].
    Jibi inkoka Otolaryngology, 1963, Volume: 35

    Topics: Adenoidectomy; Child; Cocaine; Drug Hypersensitivity; Lidocaine; Otolaryngology; Shock; Shock, Septi

1963
[CASES OF SHOCK-LIKE CONDITIONS. (8)].
    Jibi inkoka Otolaryngology, 1963, Volume: 35

    Topics: Drug Hypersensitivity; Heart Massage; Infant; Lidocaine; Otolaryngology; Resuscitation; Shock; Shock

1963
[CASE OF SUCCESSFUL TREATMENT OF SHOCK IN TONSILLECTOMY AND MEASURES FOR PREVENTING IT].
    Jibi inkoka Otolaryngology, 1963, Volume: 35

    Topics: Blood Sedimentation; Blood Transfusion; Caffeine; Cyanosis; Drug Hypersensitivity; Electrocardiograp

1963
[CASE OF SHOCK CAUSED BY LOCAL ANESTHESIA].
    Jibi inkoka Otolaryngology, 1963, Volume: 35

    Topics: Anesthesia, Local; Blood Transfusion; Cocaine; Drug Hypersensitivity; Lidocaine; Oxygen Inhalation T

1963
[5 RECENT CASES OF LOCAL ANESTHETIC TOXICITY IN TONSILLECTOMY].
    Jibi inkoka Otolaryngology, 1963, Volume: 35

    Topics: Anesthesia, Local; Anesthetics, Local; Child; Cocaine; Drug Hypersensitivity; Lidocaine; Pharmacolog

1963
USE OF TRIPELENNAMINE AND DIPHENHYDRAMINE AS LOCAL ANESTHETICS.
    Journal of the American Dental Association (1939), 1964, Volume: 69

    Topics: Anesthetics; Anesthetics, Local; Biomedical Research; Dental Care; Diphenhydramine; Drug Hypersensit

1964
DIPHENHYDRAMINE HYDROCHLORIDE (BENADRYL) AS A LOCAL ANESTHETIC IN PROCAINE AND LIDOCAINE SENSITIVE PATIENTS.
    Military medicine, 1964, Volume: 129

    Topics: Anesthesia, Dental; Anesthesia, Local; Anesthetics; Anesthetics, Local; Diphenhydramine; Drug Hypers

1964
CONDUCTION ANESTHESIA USING DIPHENHYDRAMINE HYDROCHLORIDE.
    Journal of the American Dental Association (1939), 1964, Volume: 69

    Topics: Anesthesia; Anesthesia, Conduction; Diphenhydramine; Drug Hypersensitivity; Humans; Lidocaine; Pharm

1964
MEDICAL EMERGENCIES IN THE X-RAY DEPARTMENT PREVENTION AND TREATMENT.
    The British journal of radiology, 1964, Volume: 37

    Topics: Anesthesia; Anesthetics; Anesthetics, Local; Angioedema; Barium Sulfate; Contrast Media; Drug Hypers

1964
TOXIC REACTIONS TO LOCAL ANESTHETICS.
    The Journal of the Florida Medical Association. Florida Medical Association, 1965, Volume: 52

    Topics: Anesthetics, Local; Cardiovascular Agents; Drug Hypersensitivity; Lidocaine; Postoperative Complicat

1965
[On lidocaine allergy].
    Allergie und Asthma, 1961, Volume: 7

    Topics: Drug Hypersensitivity; Humans; Hypersensitivity; Immune System Diseases; Lidocaine

1961
Evaluation of adverse reactions to local anesthetics: experience with 236 patients.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2003, Volume: 91, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Bupivacaine; Child; Child, Preschool

2003
Bone scan 14 days after a toxic lignocaine reaction.
    Clinical nuclear medicine, 2004, Volume: 29, Issue:1

    Topics: Adult; Anaphylaxis; Angioedema; Diagnosis, Differential; Drug Hypersensitivity; Female; Humans; Inci

2004
EMLA toxicity after application for allergy skin testing.
    Pediatrics, 2004, Volume: 113, Issue:2

    Topics: Anesthetics, Local; Child, Preschool; Drug Hypersensitivity; Eczema; Female; Humans; Lidocaine; Lido

2004
Evaluation of re-challenge in patients with suspected lidocaine allergy.
    Dermatology (Basel, Switzerland), 2004, Volume: 208, Issue:2

    Topics: Drug Hypersensitivity; Female; France; Humans; Injections, Subcutaneous; Lidocaine; Male; Predictive

2004
Hyaluronidase allergy after peribulbar anesthesia with orbital inflammation.
    Journal of cataract and refractive surgery, 2004, Volume: 30, Issue:4

    Topics: Aged; Anesthesia, Local; Anesthetics, Combined; Bupivacaine; Cellulitis; Drug Hypersensitivity; Fema

2004
[The problems of multiple-chemical sensitivity patients in using medicinal drugs].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2004, Volume: 124, Issue:8

    Topics: Adult; Aspirin; Caffeine; Contraindications; Drug Hypersensitivity; Drug-Related Side Effects and Ad

2004
A primigravida allegedly allergic to local anaesthetics.
    International journal of obstetric anesthesia, 2004, Volume: 13, Issue:2

    Topics: Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Lidocaine; Pregnancy; Vagina

2004
Allergic reaction to epinephrine preparation in 2% lidocaine: two case reports.
    Anesthesia progress, 2004, Volume: 51, Issue:4

    Topics: Adolescent; Anesthetics, Local; Arrhythmias, Cardiac; Drug Hypersensitivity; Edema; Epinephrine; Fem

2004
Use of preservative-free lidocaine for cataract surgery in a patient allergic to "caines".
    Journal of cataract and refractive surgery, 2005, Volume: 31, Issue:4

    Topics: Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Cataract Extraction; Drug Hypersensi

2005
Hyaluronidase allergy after peribulbar anesthesia with orbital inflammation.
    Journal of cataract and refractive surgery, 2005, Volume: 31, Issue:8

    Topics: Anesthesia, Local; Anesthetics, Combined; Bupivacaine; Cellulitis; Drug Hypersensitivity; Glucocorti

2005
Thoracotomy in a patient with a history of local anesthetic allergy.
    Anesthesia and analgesia, 2005, Volume: 101, Issue:5

    Topics: Adult; Anesthesia, Epidural; Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Lidocaine; T

2005
Anesthetic management of a labouring parturient with urticaria pigmentosa.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2006, Volume: 53, Issue:4

    Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Intravenous;

2006
Tryptase as severity marker in drug provocation tests.
    International archives of allergy and immunology, 2006, Volume: 140, Issue:2

    Topics: Acetaminophen; Adolescent; Adult; Aspirin; Diclofenac; Drug Hypersensitivity; Female; Humans; Lidoca

2006
Lidocaine hypersensitivity after subconjunctival injection.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2006, Volume: 41, Issue:2

    Topics: Abscess; Anesthetics, Local; Conjunctiva; Corneal Diseases; Drug Hypersensitivity; Humans; Injection

2006
IgE-mediated hypersensitivity reaction to lignocaine - a case report.
    Tropical biomedicine, 2005, Volume: 22, Issue:2

    Topics: Anesthesia, Dental; Anesthetics, Local; Child; Drug Hypersensitivity; Female; Humans; Hypersensitivi

2005
Obtaining a contact lens acquired electroretinogram in the presence of topical anesthetic hypersensitivity.
    Documenta ophthalmologica. Advances in ophthalmology, 2008, Volume: 116, Issue:3

    Topics: Adult; Anesthetics, Local; Contact Lenses, Hydrophilic; Drug Hypersensitivity; Electroretinography;

2008
Case reports: type I hypersensitivity to lidocaine.
    Journal of drugs in dermatology : JDD, 2007, Volume: 6, Issue:12

    Topics: Acne Keloid; Adult; Anesthetics, Local; Drug Hypersensitivity; Humans; Hypersensitivity, Immediate;

2007
Dental anesthesia with lidocaine hydrochloride for children with intractable asthma and associated allergies.
    Journal of oral therapeutics and pharmacology, 1967, Volume: 3, Issue:6

    Topics: Adolescent; Anesthesia, Dental; Anesthesia, Local; Asthma; Child; Child, Institutionalized; Dentistr

1967
Unusual reactions to tetanus toxoid.
    JAMA, 1967, Jan-09, Volume: 199, Issue:2

    Topics: Adult; Drug Hypersensitivity; Female; Humans; Lidocaine; Middle Aged; Tetanus Toxoid; Urticaria

1967
[Warnings issued by the Ministry of Health on the safety of antibiotics, anti-inflammatory analgesics and lidocaine].
    Nihon Shika Ishikai zasshi, 1984, Volume: 36, Issue:10

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Drug Hypersensitivity; Humans; Lidoc

1984
Molecular basis for the antigenicity of lidocaine analogs: tocainide and mexiletine.
    American heart journal, 1984, Volume: 107, Issue:3

    Topics: Aged; Anti-Arrhythmia Agents; Antigens; Cross Reactions; Drug Hypersensitivity; Female; Humans; Intr

1984
An unusual skin reaction following local anesthetic injection. Review of the literature and report of four cases.
    Oral surgery, oral medicine, and oral pathology, 1980, Volume: 49, Issue:1

    Topics: Arthus Reaction; Child; Drug Eruptions; Drug Hypersensitivity; Drug Tolerance; Erythema; Female; Hum

1980
[Shock syndrome caused by lidocaine hydrochloride (Xylocitin)].
    Dermatologische Monatschrift, 1984, Volume: 170, Issue:10

    Topics: Anaphylaxis; Drug Hypersensitivity; Hemodynamics; Humans; Lidocaine; Male; Middle Aged

1984
[Local anesthesia and Para group allergy].
    Zahnarztliche Praxis, 1983, Aug-12, Volume: 34, Issue:8

    Topics: Anesthetics, Local; Chemical Phenomena; Chemistry; Drug Hypersensitivity; Humans; Lidocaine; Mepivac

1983
[A rare chin skin reaction following infiltration anesthesia with 2% xylocaine. Report of 3 cases].
    Shoni shikagaku zasshi. The Japanese journal of pedodontics, 1984, Volume: 22, Issue:3

    Topics: Anesthesia, Dental; Anesthesia, Local; Child; Child, Preschool; Drug Hypersensitivity; Female; Human

1984
[Toxic and allergic reactions to local anesthetics].
    Zobozdravstveni vestnik, 1984,Summer, Volume: 39, Issue:6

    Topics: Bupivacaine; Drug Hypersensitivity; Humans; Lidocaine; Procaine

1984
Assessment of allergy to local anesthetic.
    Annals of emergency medicine, 1983, Volume: 12, Issue:5

    Topics: Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Lidocaine; Middle Aged; Parabens; Skin Te

1983
Hypersensitivity to local anaesthetics: a direct challenge test with lignocaine for definitive diagnosis.
    British medical journal (Clinical research ed.), 1982, Apr-24, Volume: 284, Issue:6324

    Topics: Adolescent; Adult; Drug Hypersensitivity; Female; Humans; Lidocaine; Male; Middle Aged

1982
Hypersensitivity to local anaesthetics: a direct challenge test with lignocaine for definitive diagnosis.
    British medical journal (Clinical research ed.), 1982, Jun-05, Volume: 284, Issue:6330

    Topics: Anesthetics, Local; Drug Hypersensitivity; Humans; Lidocaine; Skin Tests

1982
Dental drugs and anaphylactic reactions. Report of a case.
    Oral surgery, oral medicine, and oral pathology, 1980, Volume: 50, Issue:1

    Topics: Adult; Anaphylaxis; Anesthesia, Dental; Aspirin; Codeine; Drug Combinations; Drug Hypersensitivity;

1980
The relationship between in vivo and in vitro reactivity of patients with a history of allergy to local anaesthetics.
    British dental journal, 1982, Jun-01, Volume: 152, Issue:11

    Topics: Adolescent; Adult; Anesthetics, Local; Drug Hypersensitivity; Female; Humans; In Vitro Techniques; I

1982
Hypersensitivity to certain drugs in a rural population.
    The Indian journal of medical research, 1981, Volume: 73

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Drug Hypersensitivity; Humans; India; Infant; Infa

1981
Problems of peppermint-flavored lidocaine.
    The New England journal of medicine, 1980, Jan-10, Volume: 302, Issue:2

    Topics: Drug Hypersensitivity; Flavoring Agents; Humans; Lidocaine; Pharmaceutic Aids

1980
[Minor toxic effects of local anaesthetics. 7 cases (author's transl)].
    La Nouvelle presse medicale, 1980, May-03, Volume: 9, Issue:20

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Anxiety; Drug Hypersensitivity; Female; Humans; Hyper

1980
Allergic hypersensitivity to lidocaine hydrochloride.
    International journal of dermatology, 1980, Volume: 19, Issue:3

    Topics: Adolescent; Adult; Anesthesia, Dental; Child; Drug Hypersensitivity; Female; Humans; Lidocaine; Male

1980
Allergy to local anaesthetics.
    The Medical journal of Australia, 1980, Apr-19, Volume: 1, Issue:8

    Topics: Anaphylaxis; Child; Drug Hypersensitivity; Female; Humans; Lidocaine

1980
Identifying true lidocaine allergy.
    Journal of the American Dental Association (1939), 1994, Volume: 125, Issue:10

    Topics: Anesthesia, Dental; Anesthesia, Local; Dental Anxiety; Diagnosis, Differential; Drug Hypersensitivit

1994
Identifying true lidocaine allergy.
    Journal of the American Dental Association (1939), 1994, Volume: 125, Issue:10

    Topics: Anesthesia, Dental; Anesthesia, Local; Dental Anxiety; Diagnosis, Differential; Drug Hypersensitivit

1994
Identifying true lidocaine allergy.
    Journal of the American Dental Association (1939), 1994, Volume: 125, Issue:10

    Topics: Anesthesia, Dental; Anesthesia, Local; Dental Anxiety; Diagnosis, Differential; Drug Hypersensitivit

1994
Identifying true lidocaine allergy.
    Journal of the American Dental Association (1939), 1994, Volume: 125, Issue:10

    Topics: Anesthesia, Dental; Anesthesia, Local; Dental Anxiety; Diagnosis, Differential; Drug Hypersensitivit

1994
EMLA cream-induced allergic contact dermatitis: a role for prilocaine as an immunogen.
    The Journal of allergy and clinical immunology, 1995, Volume: 95, Issue:3

    Topics: Aged; Dermatitis, Allergic Contact; Drug Combinations; Drug Hypersensitivity; Female; Humans; Lidoca

1995
Skin testing after anaphylactoid reactions to dental local anesthetics. A comparison with controls.
    Oral surgery, oral medicine, and oral pathology, 1993, Volume: 75, Issue:6

    Topics: Adolescent; Adult; Aged; Anaphylaxis; Anesthesia, Dental; Anesthetics, Local; Chi-Square Distributio

1993
Delayed-type hypersensitivity after subcutaneous administration of amide anesthetic.
    Archives of dermatology, 1996, Volume: 132, Issue:10

    Topics: Aged; Amides; Anesthetics, Local; Drug Eruptions; Drug Hypersensitivity; Female; Humans; Hypersensit

1996
Lignocaine toxicity following pleurodesis.
    The Journal of the Association of Physicians of India, 1995, Volume: 43, Issue:6

    Topics: Adult; Drug Hypersensitivity; Humans; Hypersensitivity, Immediate; Lidocaine; Male; Middle Aged; Ple

1995
Unusual complications of intermittent self-catheterisation in spinal cord injury patients.
    Spinal cord, 1996, Volume: 34, Issue:12

    Topics: Adult; Anesthetics, Local; Drug Hypersensitivity; Equipment Failure; Female; Humans; Lidocaine; Male

1996
T cell reactions in patients showing adverse immune reactions to drugs.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1996, Volume: 45 Suppl 2

    Topics: Adult; Anesthetics, Local; Anti-Infective Agents; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphoc

1996
Allergic reaction caused by local anesthetic agents belonging to the amide group.
    The Journal of allergy and clinical immunology, 1997, Volume: 99, Issue:3

    Topics: Adult; Allergens; Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Immunoglobulin E; Lidoc

1997
How to avoid local anaesthetic toxicity.
    British dental journal, 1998, Apr-11, Volume: 184, Issue:7

    Topics: Adult; Aged; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Body Weight; Child; Child, P

1998
Allele-unrestricted presentation of lidocaine by HLA-DR molecules to specific alphabeta+ T cell clones.
    International immunology, 1998, Volume: 10, Issue:4

    Topics: Adult; Alleles; Anesthetics, Local; Animals; Antigen-Presenting Cells; Clone Cells; Drug Hypersensit

1998
Lignocaine and anaesthetic allergy.
    British dental journal, 1998, Nov-14, Volume: 185, Issue:9

    Topics: Adult; Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Incidence; Lidocaine; Prilocaine;

1998
Recognition of local anesthetics by alphabeta+ T cells.
    The Journal of investigative dermatology, 1999, Volume: 112, Issue:2

    Topics: Anesthetics, Local; Cell Line; Clone Cells; Cross Reactions; Drug Hypersensitivity; Epitopes; Humans

1999
Sight-threatening acute orbital swelling from peribulbar local anesthesia.
    Journal of cataract and refractive surgery, 1999, Volume: 25, Issue:3

    Topics: Acute Disease; Aged; Anesthetics, Local; Drug Hypersensitivity; Edema; Female; Follow-Up Studies; Gl

1999
Allergic reactions to lignocaine.
    British dental journal, 1999, Mar-13, Volume: 186, Issue:5

    Topics: Adult; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Diagnosis, Differential; Drug Hype

1999
Anaphylactic reaction to lidocaine.
    Australian dental journal, 1999, Volume: 44, Issue:1

    Topics: Adolescent; Anaphylaxis; Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Hypersensitivity

1999
Adverse reactions possibly associated with the use of Emla cream.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1999, Volume: 89, Issue:4

    Topics: Anesthetics, Combined; Anesthetics, Local; Child; Drug Hypersensitivity; Female; Humans; Lidocaine;

1999
[The use of EMLA cream in pediatrics].
    Annales de dermatologie et de venereologie, 1999, Volume: 126, Issue:3

    Topics: Anesthetics, Combined; Anesthetics, Local; Child; Drug Hypersensitivity; Humans; Lidocaine; Lidocain

1999
An adverse effect of carboxymethylcellulose in lidocaine jelly.
    Anesthesiology, 1999, Volume: 91, Issue:6

    Topics: Aged; Anesthetics, Local; Carboxymethylcellulose Sodium; Drug Hypersensitivity; Female; Gels; Humans

1999
Lidocaine toxicity in a student undergoing upper gastrointestinal endoscopy.
    Gut, 2000, Volume: 46, Issue:3

    Topics: Adult; Anesthetics, Local; Drug Hypersensitivity; Fatal Outcome; Humans; Lidocaine; Male

2000
Adverse reaction to dental local anaesthetic injection--'allergy' is not the cause.
    British dental journal, 2000, Oct-14, Volume: 189, Issue:7

    Topics: Anesthesia, Dental; Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Immunologic Tests; In

2000
Local anaesthetics.
    British dental journal, 2000, Dec-23, Volume: 189, Issue:12

    Topics: Anesthesia, Dental; Anesthetics, Local; Drug Hypersensitivity; Humans; Lidocaine; Maximum Tolerated

2000
Simultaneous [correction of Spontaneous] allergy to ampicillin and local anesthetics.
    Allergy, 2001, Volume: 56, Issue:5

    Topics: Ampicillin; Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Hypersensitivity, Delayed; In

2001
Just the berries. Allergy to local anesthetics.
    Canadian family physician Medecin de famille canadien, 2001, Volume: 47

    Topics: Aged; Anesthetics, Local; Drug Hypersensitivity; Humans; Lacerations; Lidocaine; Male; Skin Test End

2001
Allergic response to metabisulfite in lidocaine anesthetic solution.
    Anesthesia progress, 2001,Winter, Volume: 48, Issue:1

    Topics: Adult; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Antioxidants; Drug Hypersensitivit

2001
Post-extraction complications seen at a referral dental clinic in Dar Es Salaam, Tanzania.
    International dental journal, 2001, Volume: 51, Issue:4

    Topics: Abscess; Adolescent; Adult; Ambulatory Surgical Procedures; Anesthesia, Dental; Anesthetics, Local;

2001
A pregnant woman with previous anaphylactic reaction to local anesthetics: a case report.
    American journal of obstetrics and gynecology, 2001, Volume: 185, Issue:5

    Topics: Adult; Anaphylaxis; Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Lidocaine; Pregnancy;

2001
Sensitivity to local anaesthetics among asthmatic children.
    International journal of paediatric dentistry, 2001, Volume: 11, Issue:6

    Topics: Adolescent; Allergens; Anesthetics, Local; Animals; Asthma; Child; Drug Hypersensitivity; Female; Hu

2001
Evaluating a dental patient for local anesthesia allergy.
    Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995), 2002, Volume: 23, Issue:2

    Topics: Aged; Allergens; Anesthesia, Dental; Anesthetics, Local; Drug Hypersensitivity; Exanthema; Humans; H

2002
[A study of allergy to local anesthetics using the lymphoblast transformation test].
    Annales de l'anesthesiologie francaise, 1976, Volume: 17, Issue:3

    Topics: Adult; Anesthetics, Local; Chemical Phenomena; Chemistry; Drug Hypersensitivity; Female; Humans; Lid

1976
Letter: Presumed generalized exfoliative dermatitis to lidocaine.
    Archives of dermatology, 1975, Volume: 111, Issue:2

    Topics: Adult; Anesthesia, Dental; Dermatitis, Exfoliative; Drug Hypersensitivity; Humans; Lidocaine; Male

1975
Discussion of sensitivity to preservatives in anesthetics.
    Journal of the American Dental Association (1939), 1978, Volume: 97, Issue:4

    Topics: Adult; Anesthesia, Dental; Drug Hypersensitivity; Female; Humans; Lidocaine; Parabens; Pharmaceutic

1978
Sensitivity to lignocaine.
    Anaesthesia and intensive care, 1979, Volume: 7, Issue:1

    Topics: Anesthesia, Local; Drug Hypersensitivity; Humans; Lidocaine; Skin Tests

1979
Sensitivity to lignocaine.
    Anaesthesia and intensive care, 1977, Volume: 5, Issue:4

    Topics: Aged; Drug Hypersensitivity; Humans; Lidocaine; Male; Syncope

1977
[Apropos of a severe complication of local anesthesia using xylocaine].
    Bulletin de la Societe medicale d'Afrique noire de langue francaise, 1977, Volume: 22, Issue:3

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Drug Hypersensitivity; Female; Hiccup; Humans; Lidoca

1977
Vertical pendular nystagmus in chronic myositis of medial and lateral rectus.
    Annals of ophthalmology, 1978, Volume: 10, Issue:12

    Topics: Adult; Chronic Disease; Diplopia; Drug Hypersensitivity; Female; Humans; Lidocaine; Mepivacaine; Myo

1978
Adverse reactions to local anaesthetics and vasoconstrictor drugs.
    The Practitioner, 1975, Volume: 214, Issue:1281

    Topics: Anaphylaxis; Anesthesia, Dental; Anesthetics, Local; Arteriosclerosis; Blood Pressure; Coronary Dise

1975
Deaths from paracervical anesthesia used for first-trimester abortion, 1972-1975.
    The New England journal of medicine, 1976, Dec-16, Volume: 295, Issue:25

    Topics: Abortion, Induced; Adolescent; Adult; Anesthesia, Obstetrical; Cervix Uteri; Dose-Response Relations

1976
Deaths from paracervical anesthesia used for first-trimester abortion, 1972-1975.
    The New England journal of medicine, 1976, Dec-16, Volume: 295, Issue:25

    Topics: Abortion, Induced; Adolescent; Adult; Anesthesia, Obstetrical; Cervix Uteri; Dose-Response Relations

1976
Deaths from paracervical anesthesia used for first-trimester abortion, 1972-1975.
    The New England journal of medicine, 1976, Dec-16, Volume: 295, Issue:25

    Topics: Abortion, Induced; Adolescent; Adult; Anesthesia, Obstetrical; Cervix Uteri; Dose-Response Relations

1976
Deaths from paracervical anesthesia used for first-trimester abortion, 1972-1975.
    The New England journal of medicine, 1976, Dec-16, Volume: 295, Issue:25

    Topics: Abortion, Induced; Adolescent; Adult; Anesthesia, Obstetrical; Cervix Uteri; Dose-Response Relations

1976
Allergic reaction to lignocaine. A case report.
    British dental journal, 1975, Feb-04, Volume: 138, Issue:3

    Topics: Anesthesia, Dental; Anesthesia, Local; Child; Drug Hypersensitivity; Edema; Eyelid Diseases; Female;

1975
[A case of early-type hypersesitivity to lignocaine].
    Czasopismo stomatologiczne, 1976, Volume: 29, Issue:6

    Topics: Adult; Anesthesia, Dental; Drug Hypersensitivity; Edema; Female; Humans; Lidocaine

1976
[Clinical and experimental contribution to the pathogenesis of acute life-threatening incidents following neck anesthesia].
    Schweizerische medizinische Wochenschrift, 1975, Jan-11, Volume: 105, Issue:2

    Topics: Acute Disease; Anaphylaxis; Anesthesia, Epidural; Anesthesia, Local; Anesthetics; Drug Hypersensitiv

1975
Letter: Deaths due to local analgesia in dentistry.
    Anaesthesia, 1975, Volume: 30, Issue:5

    Topics: Anesthesia, Dental; Anesthesia, Intravenous; Carotid Arteries; Drug Hypersensitivity; Humans; Lidoca

1975
PAF acether release on antigenic challenge. A method for the investigation of drug allergic reactions.
    Allergy, 1992, Volume: 47, Issue:1

    Topics: Antigens; Aspirin; Drug Hypersensitivity; Humans; Immunoglobulin E; Leukocytes; Lidocaine; Lymphocyt

1992
Type IV allergy to amide-type local anesthetics.
    Contact dermatitis, 1991, Volume: 25, Issue:1

    Topics: Anesthetics, Local; Cross Reactions; Drug Hypersensitivity; Female; Humans; Hypersensitivity, Delaye

1991
[A case of eosinophilic pneumonitis with drug hypersensitivity].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1991, Jan-10, Volume: 80, Issue:1

    Topics: Alveolitis, Extrinsic Allergic; Atropine; Cefixime; Cefotaxime; Drug Hypersensitivity; Female; Human

1991
Tocainide: interstitial pneumonitis.
    Journal of the American College of Cardiology, 1990, Volume: 15, Issue:6

    Topics: Aged; Anti-Arrhythmia Agents; Drug Hypersensitivity; Humans; Lidocaine; Male; Pulmonary Fibrosis; To

1990
Local anesthesia in dermatologic surgery.
    Journal of the American Academy of Dermatology, 1990, Volume: 22, Issue:1

    Topics: Anesthesia, Local; Dermatologic Surgical Procedures; Drug Hypersensitivity; Humans; Lidocaine; Skin

1990
Supersensitivity to subcutaneous lidocaine.
    Clinical pharmacy, 1990, Volume: 9, Issue:5

    Topics: Administration, Cutaneous; Drug Hypersensitivity; Humans; Lidocaine; Male; Middle Aged

1990
[Management of suspected allergy to lidocaine].
    Allergie et immunologie, 1986, Volume: 18, Issue:3

    Topics: Drug Hypersensitivity; Female; Histamine Release; Humans; Lidocaine; Lymphocyte Activation; Postoper

1986
Local anesthetic intolerance due to metabisulfite.
    Contact dermatitis, 1989, Volume: 20, Issue:2

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Drug Combinations; Drug Hypersensitivity; Female; Hum

1989
Tocainide: a severe adverse reaction.
    Drug intelligence & clinical pharmacy, 1988, Volume: 22, Issue:2

    Topics: Aged; Anti-Arrhythmia Agents; Drug Eruptions; Drug Hypersensitivity; Humans; Lidocaine; Male; Tocain

1988
Tocainide-induced granulomatous hepatitis.
    JAMA, 1986, Jun-27, Volume: 255, Issue:24

    Topics: Anti-Arrhythmia Agents; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Granuloma; Hu

1986
Fatal bronchospasm after topical lignocaine before bronchoscopy.
    British medical journal (Clinical research ed.), 1987, Jun-27, Volume: 294, Issue:6588

    Topics: Administration, Topical; Aged; Bronchial Spasm; Bronchoscopy; Drug Hypersensitivity; Humans; Lidocai

1987
Fatal bronchospasm after topical lignocaine before bronchoscopy.
    British medical journal (Clinical research ed.), 1987, Sep-05, Volume: 295, Issue:6598

    Topics: Bronchial Spasm; Bronchoscopy; Drug Hypersensitivity; Humans; Lidocaine; Male

1987
An answer for a questionable allergy to local anesthetics.
    Annals of emergency medicine, 1988, Volume: 17, Issue:5

    Topics: Drug Hypersensitivity; Humans; Lidocaine; Parabens

1988
Considerations in differential diagnosis of adverse reactions to local anesthetic: report of case.
    Journal of the American Dental Association (1939), 1986, Volume: 113, Issue:2

    Topics: Anesthesia, Dental; Anesthesia, Local; Diagnosis, Differential; Drug Hypersensitivity; Female; Human

1986
Provocative challenge with local anesthetics in patients with a prior history of reaction.
    The Journal of allergy and clinical immunology, 1987, Volume: 79, Issue:6

    Topics: Anaphylaxis; Anesthetics, Local; Drug Hypersensitivity; Humans; Intradermal Tests; Lidocaine; Procai

1987
[A pediatric case of lidocaine hypersensitivity].
    Masui. The Japanese journal of anesthesiology, 1987, Volume: 36, Issue:4

    Topics: Adolescent; Anesthesia, Dental; Drug Hypersensitivity; Female; Humans; Lidocaine

1987
Local anesthesia. Implications for the perioperative nurse.
    AORN journal, 1987, Volume: 45, Issue:3

    Topics: Adult; Anesthesia, Local; Anesthetics, Local; Documentation; Drug Hypersensitivity; Female; Humans;

1987
[Allergic angioedema after local dental anesthesia and a hyaluronidase-containing preanesthetic injection solution].
    Schweizerische medizinische Wochenschrift, 1986, Dec-20, Volume: 116, Issue:51

    Topics: Adult; Anesthesia, Dental; Anesthesia, Local; Angioedema; Drug Hypersensitivity; Female; Humans; Hya

1986
Allergy to lidocaine and mepivacaine: report of a case.
    The Compendium of continuing education in dentistry, 1985, Volume: 6, Issue:4

    Topics: Adult; Drug Hypersensitivity; Humans; Hypersensitivity, Immediate; Lidocaine; Male; Mepivacaine

1985
Anaphylactic reaction to lidocaine.
    Archives of otolaryngology--head & neck surgery, 1986, Volume: 112, Issue:6

    Topics: Adult; Anaphylaxis; Bupivacaine; Drug Evaluation; Drug Hypersensitivity; Female; Humans; Intradermal

1986
Nasal test for hypersensitivity. Including a positive reaction to lignocaine.
    Lancet (London, England), 1971, Feb-06, Volume: 1, Issue:7693

    Topics: Adult; Anesthesia, Dental; Drug Hypersensitivity; Female; Humans; Lidocaine; Methods; Nose; Solution

1971
Lignocaine hypersensitivity.
    Lancet (London, England), 1971, Jun-12, Volume: 1, Issue:7711

    Topics: Anesthesia, Local; Drug Hypersensitivity; Humans; Lidocaine; Lymphocyte Activation; Skin Tests

1971
The rat mast cell degranulation assay as an in vitro allergy test.
    Australian and New Zealand journal of medicine, 1974, Volume: 4, Issue:2

    Topics: Age Factors; Animals; Cycloserine; Cytoplasmic Granules; Dextrans; Drug Hypersensitivity; Histamine

1974
[Complications of regional anaesthesia and their treatment (author's transl)].
    Munchener medizinische Wochenschrift (1950), 1973, Oct-12, Volume: 115, Issue:41

    Topics: Adrenal Cortex Hormones; Anesthesia, Local; Apnea; Barbiturates; Bradycardia; Bupivacaine; Diagnosis

1973
Local anaesthetic sensitivity. Case report.
    Australian dental journal, 1972, Volume: 17, Issue:1

    Topics: Antigen-Antibody Reactions; Asthma; Drug Hypersensitivity; Edema; Epinephrine; Female; Humans; Hyper

1972
[A case of lidocaine allergy].
    Fogorvosi szemle, 1972, Volume: 65, Issue:2

    Topics: Drug Hypersensitivity; Humans; Lidocaine; Skin Tests

1972
[Lidocaine hypersensitivity].
    Fogorvosi szemle, 1973, Volume: 66, Issue:1

    Topics: Adolescent; Adult; Anesthesia, Dental; Drug Hypersensitivity; Humans; Lidocaine; Male; Skin Tests

1973
Sensitivity to local anaesthetic.
    Australian dental journal, 1972, Volume: 17, Issue:5

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Benzoates; Drug Hypersensitivity; Female; Humans; Lid

1972
Local anaesthetic sensitivity. Case report.
    Newsletter. International College of Dentists. India Section, 1972, Volume: 9, Issue:4

    Topics: Anesthesia, Dental; Drug Hypersensitivity; Lidocaine

1972
A case of lignocaine hypersensitivity.
    British dental journal, 1973, Nov-06, Volume: 135, Issue:9

    Topics: Adolescent; Drug Hypersensitivity; Female; Humans; Lidocaine; Nasal Mucosa; Procaine; Skin Tests; Ur

1973
Local anesthetic reactions: prevention, diagnosis, treatment.
    Journal of the South Carolina Medical Association (1975), 1974, Volume: 70, Issue:11

    Topics: Aged; Anesthesia, Local; Drug Hypersensitivity; Female; Humans; Lidocaine; Male; Middle Aged; Tetrac

1974
The effect of local anesthesia with epinephrine on skin flap survival.
    Plastic and reconstructive surgery, 1974, Volume: 54, Issue:3

    Topics: Anesthesia, Local; Animals; Drug Hypersensitivity; Epinephrine; Lidocaine; Necrosis; Skin; Skin Tran

1974
[Iatrogenic lesion in ophthalmologic anesthesia].
    Klinische Monatsblatter fur Augenheilkunde, 1972, Volume: 161, Issue:3

    Topics: Adult; Aged; Anesthesia, General; Anesthesia, Local; Anesthetics; Anesthetics, Local; Atropine; Blin

1972
Curettage as an office procedure.
    American journal of obstetrics and gynecology, 1974, May-01, Volume: 119, Issue:1

    Topics: Abortion, Therapeutic; Anesthesia, Local; Costs and Cost Analysis; Curettage; Dilatation; Drug Hyper

1974
Fever, vomiting, and liver dysfunction with procainamide therapy.
    Postgraduate medicine, 1974, Volume: 56, Issue:1

    Topics: Ampicillin; Blood; Chemical and Drug Induced Liver Injury; Digitalis; Drug Hypersensitivity; Female;

1974
Recent experiences with intravenous regional anesthesia in limbs.
    The Journal of trauma, 1972, Volume: 12, Issue:1

    Topics: Anesthesia, Conduction; Anesthesia, Intravenous; Arm; Drug Hypersensitivity; Foot; Hand; Humans; Leg

1972
Extreme epinephrine sensitivity with a general anesthesia.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1972, Volume: 96, Issue:3

    Topics: Adult; Anesthesia, Inhalation; Arrhythmias, Cardiac; Blood Pressure; Child; Drug Hypersensitivity; D

1972
An acute immune response to intra-articular injection of osmium tetroxide.
    Acta rheumatologica Scandinavica, 1971, Volume: 17, Issue:3

    Topics: Arthritis, Rheumatoid; Creatinine; Drug Hypersensitivity; Female; Humans; Injections, Intra-Articula

1971
Evaluation of patients with history of allergy to local anesthetic drugs.
    Southern medical journal, 1971, Volume: 64, Issue:9

    Topics: Adolescent; Adult; Aged; Anesthetics, Local; Child; Drug Hypersensitivity; Female; Humans; Lidocaine

1971
Local anaesthetics.
    Laval medical, 1971, Volume: 42, Issue:8

    Topics: Amides; Anesthetics, Local; Brain Edema; Cardiovascular Diseases; Central Nervous System Diseases; C

1971
Lidocaine hypersensitivity: report of a case.
    Journal of the American Dental Association (1939), 1967, Volume: 74, Issue:4

    Topics: Adult; Anesthesia, Dental; Drug Hypersensitivity; Epinephrine; Female; Humans; Lidocaine

1967
Hypersensitivity to lidocaine hydrochloride. Report of a case.
    Oral surgery, oral medicine, and oral pathology, 1969, Volume: 28, Issue:5

    Topics: Adult; Drug Hypersensitivity; Humans; Lidocaine; Male

1969
[Studies of the skin test of local anesthetic drugs and the interview test of outpatients in dental clinical offices].
    Kyoto Daigaku kokukagaku kiyo. Bulletin of stomatology, Kyoto University, 1969, Volume: 9, Issue:1

    Topics: Drug Hypersensitivity; Lidocaine; Skin Tests

1969
[Allergic skin reactions to topical anesthetics in patients with bronchial asthma].
    Czasopismo stomatologiczne, 1971, Volume: 24, Issue:5

    Topics: Asthma; Drug Hypersensitivity; Humans; Lidocaine; Procaine; Skin Tests

1971
More about the "allergic reaction to lidocaine".
    Anesthesiology, 1970, Volume: 32, Issue:3

    Topics: Drug Hypersensitivity; Humans; Lidocaine

1970
An "allergic" reaction?
    Anesthesiology, 1970, Volume: 32, Issue:2

    Topics: Anesthesia, Local; Drug Hypersensitivity; Humans; Lidocaine; Skin Tests

1970
[Prothanon eyedrops. 1. Results of experimental animal and orientative clinical studies].
    Die Pharmazie, 1970, Feb-02, Volume: 25, Issue:2

    Topics: Anesthetics, Local; Animals; Conjunctivitis; Cornea; Drug Hypersensitivity; Drug Tolerance; Eye; Hum

1970
Hypersensitivity reaction to lignocaine.
    Journal of the Royal Naval Medical Service, 1971,Spring, Volume: 57, Issue:1

    Topics: Drug Hypersensitivity; Female; Humans; Lidocaine

1971
[Test for drug sensitization in patients with cerebral stroke].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1969, Volume: 24, Issue:14

    Topics: Adult; Aged; Cerebrovascular Disorders; Drug Hypersensitivity; Female; Hemiplegia; Humans; Lidocaine

1969
A suspected allergic reaction to lidocaine.
    Anesthesiology, 1969, Volume: 31, Issue:4

    Topics: Anaphylaxis; Drug Hypersensitivity; Humans; Hypersensitivity, Delayed; Lidocaine; Male; Middle Aged;

1969
Diphenhydramine for local anesthesia in "caine" sensitive patients. A case report.
    Journal of the American Podiatry Association, 1966, Volume: 56, Issue:1

    Topics: Adult; Anesthesia, Local; Diphenhydramine; Drug Hypersensitivity; Female; Humans; Lidocaine; Warts

1966
Anaphylaxis from alphazurine 2G during lymphography.
    JAMA, 1966, Nov-07, Volume: 198, Issue:6

    Topics: Adult; Coloring Agents; Diphenhydramine; Drug Hypersensitivity; Epinephrine; Hodgkin Disease; Humans

1966
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