lidocaine has been researched along with Disease Models, Animal in 342 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 56 (16.37) | 18.7374 |
| 1990's | 49 (14.33) | 18.2507 |
| 2000's | 84 (24.56) | 29.6817 |
| 2010's | 133 (38.89) | 24.3611 |
| 2020's | 20 (5.85) | 2.80 |
| Authors | Studies |
|---|---|
| Baizman, ER; Becker, C; Bell, RH; Birsner, NC; Bohnet, EA; Busacca, CA; Carabateas, PM; Chadwick, CC; Gruett, MD; Johnson, RE | 1 |
| Bajda, M; Brus, B; Czerwińska, P; Filipek, B; Gobec, S; Malawska, B; Sałat, K; Więckowska, A; Więckowski, K | 1 |
| Braisted, J; Dranchak, P; Earnest, TW; Gu, X; Hoon, MA; Inglese, J; Oliphant, E; Solinski, HJ | 1 |
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Biros, E; Dobson, GP; Letson, HL; Morris, JL | 2 |
| Bingham, JR; Conner, JR; Eckert, MJ; Franko, JJ; Ieronimakis, N; Lammers, DT; Parsons, ME; Reynolds, GD; Vu, MM | 1 |
| Adkson Sales Lima, C; Amato, MBP; Brochard, L; Costa, ELV; Goligher, EC; Ho, YL; Morais, CCA; Nakamura, MAM; Pereira, SM; Ranzani, OT; Sinedino, BE; Sklar, MC; Taniguchi, LU; Tucci, MR; Vieira, JE | 1 |
| Chen, YS; Hsieh, ST; Wang, YC | 1 |
| Biros, E; Birosova, E; Moran, CS | 1 |
| Biben, JA; Prasetyono, TOH; Tantri, AR | 1 |
| Chim, H; Miller, NL; Pearse, DD; Rao, S; Salgado, CJ; Wolfe, EM | 1 |
| Albaiceta, GM; Amado-Rodríguez, L; Francis, RCE; González-López, A; Kuebler, W; López-Alonso, I; Niendorf, T; Pickerodt, PA; Reimann, H; Spies, CD; von Haefen, C | 1 |
| Han, SW; Kang, HJ; Kim, JH; Kim, SW; Lee, YS | 1 |
| Andrews, NA; Bean, BP; Heckman, LM; Jacquemont, T; Jain, A; Jo, S; Kotoda, M; Lee, J; Lee, S; Liu, PW; Pascal, M; Puopolo, M; Talbot, S; Woolf, CJ; Zhang, HB | 1 |
| Bai, K; Chen, Y; He, J; Hong, B; Huang, W; Le, Q | 1 |
| Alexa-Stratulat, T; Cojocaru, E; Harabagiu, V; Leon-Constantin, MM; Luca, A; Tamba, BI; Trandafir, LM | 1 |
| Chen, JC; Chen, JM; Liu, KC; Liu, SJ; Yeh, WL | 1 |
| Dobson, GP; Granfeldt, A; Jensen, TH; Letson, HL; Mattson, TH | 1 |
| Abdalla, HB; Burga-Sánchez, J; da Costa, JP; de Freitas Domingues, JS; Ferreira, LEN; Groppo, FC; Volpato, MC | 1 |
| Dobson, GP; Letson, HL | 3 |
| Cheng, Z; Guo, Q; Jian, Y; Song, Z; Wang, E; Wang, J; Wang, Y; Wu, L; Zhang, Z | 1 |
| Han, HC; Lee, SW; Moon, SW; Park, JS; Suh, HR | 1 |
| Brown, DR; Cardin, S; Glaser, JJ; Hathaway, EN; Hemond, PJ; Morgan, CG; Neidert, LE; Salas, M; Stigall, KS; Tiller, MM | 1 |
| Earnest, R; Goodman, MD; McGlone, E; Morris, MC; Singer, KE; Stevens-Topie, S; Wallen, TE | 1 |
| Buggy, DJ; Crowley, PD; Wall, TP | 1 |
| He, C; Li, B; Tu, Y; Xu, H; Zou, W | 1 |
| Karthik, F; Kirschner, A; Koch, SE; Lorenz, JN; Mudigonda, P; Nieman, ML; Ramasubramanian, R; Robbins, N; Rubinstein, J | 1 |
| Bingham, J; Conner, J; Dobson, G; Eckert, M; Holtestaul, T; Jones, I; Kuckelman, J; Lammers, D; Letson, H | 1 |
| Baek, CW; Cho, WJ; Choi, GJ; Hong, ME; Jung, YH; Kang, H; Kim, JW; Lee, Y; Park, ILK; Shin, HY | 1 |
| Allen, J; Havelin, J; Henderson, T; Imbert, I; King, T; Liaw, L; Stevenson, G | 1 |
| Feng, GG; Fujiwara, Y; Kazaoka, Y; Kinoshita, H; Saito, T; Yamamoto, Y | 1 |
| Chen, J; Ding, H; Fu, YJ; Shi, XQ; Zheng, LR | 1 |
| Fu, YJ; Shi, XQ; Zheng, LR | 1 |
| Davenport, L; Dobson, GP; Letson, HL | 1 |
| Asiri, YI; Asseri, KA; Barr, AM; Fung, T; MacLeod, BA; Puil, E; Schuppli, CA; Schwarz, SKW; Wall, RA; Welch, ID | 1 |
| Chang, YT; Chen, CC; Chen, WH; Chen, YH; Cheng, YF; Shih, HC; Shyu, BC | 1 |
| Chen, WS; Huang, WT; Huang, YY; Kuo, PL; Lin, KH; Luh, JJ | 1 |
| Baptista-Hon, D; Bull, F; Dalgaty, F; Gallacher, M; Hales, TG; Ibbotson, SH; Wright, L | 1 |
| Sunada, K; Tsutsui, Y | 1 |
| de Bruin, K; Hollmann, MW; Horn, J; Lirk, P; Picardi, S; Rigaud, M; Tan, HL; Ten Hoope, W; Verberne, HJ; Verhamme, C; Verkerk, AO | 1 |
| Cheng, K; King, T; Li, F; Li, N; Nippert, A; Porreca, F; Remeniuk, B; Rice, KC; Sukhtankar, D | 1 |
| Kim, DP; Klein, JA; Klein, PA; Makdisi, JR | 1 |
| Bruzzese, E; Cuomo, R; D'Alessandro, A; Esposito, G; Gigli, S; Lattanzi, R; Lu, J; Pesce, M; Sarnelli, G; Seguella, L; Steardo, L | 1 |
| Fang, L; Li, S; Liu, R; Shen, Q; Wang, L; Wang, M; Wu, H; Zhang, S | 1 |
| Hua, R; Ji, NN; Kang, J; Zhang, YM | 1 |
| Breda, SA; Manzo, RH; Olivera, ME; Sanchez, MF; Soria, EA; Tártara, LI | 1 |
| Chen, W; Marvizón, JC; Taché, Y | 1 |
| Broomhead, M; Eriksson, E; Nuutila, K; Proppe, K; Yang, L | 1 |
| Eskandari, M; Sarchahi, AA | 1 |
| Chakraborty, S; Raju, TR; Shankaranarayana Rao, BS; Srikumar, BN; Tripathi, SJ | 1 |
| Cantet, RJC; Nishida, F; Portiansky, EL; Sisti, MS; Zanuzzi, CN | 1 |
| Alptekin, NÖ; Bilgin Çetin, M; Börçek, P; Bulut, Ş; Sezgin, Y | 1 |
| Chen, J; Ding, H; Fu, YJ; Shi, XQ; Zhang, SS | 1 |
| Araya, EI; Chichorro, JG; Claudino, RF; de Oliveira, SB; Ferreira, LEN; Franz-Montan, M; Gambeta, E | 1 |
| Cantet, RJC; Laurella, SL; Nishida, F; Portiansky, EL; Sisti, MS; Zanuzzi, CN | 1 |
| Choi, SH; Kim, JM | 1 |
| Cardin, S; Fryer, DM; Glaser, JJ; How, RA; Morgan, CG; Ozuna, KM; Sams, VG; Schaub, LJ | 1 |
| Khrestian, A; Khrestian, CM; Lee, S; Markowitz, A; Sahadevan, J; Waldo, AL | 1 |
| Iwasaki, K; Iwasaki, N; Sudo, H; Tsujimoto, T; Ukeba, D; Ura, K | 1 |
| Bauer, CA; Brozoski, TJ; Kurt, W; Sybert, LT | 1 |
| Blaha, CD; Dickson, PE; Goldowitz, D; Heck, DH; McKimm, E; Mittleman, G; Rogers, TD | 1 |
| Bargas, J; Carrillo-Reid, L; Drucker-Colin, R; Fiordelisio, T; Galarraga, E; López-Huerta, VG; Tapia, D | 1 |
| Dong, Z; Gong, Y; Li, X; Shan, B; Shen, L; Shu, X; Wang, Z; Zhang, L | 1 |
| De Felice, M; Guo, W; King, T; Ossipov, MH; Porreca, F; Wang, R | 1 |
| Niemann, JT; Rosborough, JP; Shah, AP; Thomas, JL; Youngquist, ST | 1 |
| Griffith, BP; Li, T; Sanchez, PG; Watkins, AC; Wei, X; Wu, ZJ | 1 |
| Bone, CC; Cline, JM; Dobson, GP; Granfeldt, A; Jiang, R; Schmarkey, SL; Shi, W; Tønnesen, E; Vinten-Johansen, J; Wogensen, L | 1 |
| Bertram, JE; Gutmann, A; Hurtig, M; Matyas, JR; Randev, J | 1 |
| Ansah, OB; Linderoth, B; Meyerson, BA; Pertovaara, A; Song, Z | 1 |
| Liu, J; Qi, Z; Zhang, H; Zheng, X | 1 |
| Aschenbrenner, CA; Eisenach, JC; Houle, TT; Peters, CM; Ririe, D | 1 |
| Ohki, M; Takeuchi, N | 1 |
| Dobson, GP; Granfeldt, A; Hyldebrandt, JA; Letson, HL; Nielsen, TK; Salcedo, PA; Tønnesen, E; Vinten-Johansen, J; Wang, ER | 1 |
| Heo, T; Hun Jung, Y; Il Min, Y; Jeong, IS; Joon Lee, S; Kook Lee, B; Lim, V; Woon Jeung, K; Youn Lee, H | 1 |
| Cao, J; Tan, H; Zhang, J; Zuo, Z | 1 |
| Bai, N; Chen, YZ; Fu, Y; Lin, Q; Mao, KP; Xue, Y | 1 |
| Dobson, GP; Griffin, MJ; Letson, HL | 2 |
| Aguila, J; Cudeiro, J; Rivadulla, C | 1 |
| Catterall, WA; Jones, CJ; Rubinstein, M; Scheuer, T; Westenbroek, RE; Yu, FH | 1 |
| Ba-M'hamed, S; Bennis, M; Ouhaz, Z | 1 |
| Chen, J; Fu, Y; Green, TA; Guptarak, J; Jensen, KL; Sarna, SK; Shi, XZ; Winston, JH | 1 |
| Khodagholi, F; Motamedi, F; Nategh, M; Nikseresht, S | 1 |
| Dobson, GP; Granfeldt, A; Letson, HL; Shi, W; Tønnesen, E; Vinten-Johansen, J | 1 |
| Abe, T; Igarashi, T; Inoue, K; Katori, N; Kosugi, S; Minamishima, S; Mori, K; Morisaki, H; Sano, F; Seki, H; Suzuki, T; Yamada, T | 1 |
| Cui, W; Han, R; Li, J; Wang, Q; Wang, S | 1 |
| Frank, JE; Glickman, LT; Gordon, CJ; Katz, LM; Lambert, BH; McGwin, G | 1 |
| King, T; Navratilova, E; Okun, A; Porreca, F; Remeniuk, B; Sukhtankar, D; Xie, JY | 1 |
| Alvarez, P; Green, PG; Levine, JD | 1 |
| Abdulnour, RE; Agac, B; Bean, BP; Burkett, PR; Chiu, IM; Cronin, SJ; DiBiase, M; Foster, SL; Ghasemlou, N; Haworth, O; Kuchroo, VK; Laedermann, C; Lai, N; Lee, S; Levy, BD; Pascal, MA; Penninger, JM; Roberson, D; Seki, H; Talbot, S; Tran, JV; Von Hehn, C; Woolf, CJ | 1 |
| Kharatmal, SB; Sharma, SS; Singh, JN | 1 |
| Chang, LL; Chen, PL; Cheng, KI; Chou, CW; Chuang, YT; Lai, CS; Tseng, KY; Wang, HC; Wu, YC | 1 |
| Almeida, A; Amorim, D; Pertovaara, A; Pinto-Ribeiro, F; Viisanen, H; Wei, H | 1 |
| Anjos-Valotta, EA; Cordeiro, RS; Costa, JC; Cotias, AC; Couto, GC; de Carvalho, KI; Faria, RX; Martins, MA; Neves, JS; Olsen, PC; Pão, CR; Serra, MF; Silva, PM | 1 |
| Allen, J; Cormier, J; Havelin, J; Imbert, I; King, T; Porreca, F | 1 |
| Goto, T; Harano, N; Hitomi, S; Inenaga, K; Inoue, H; Ito, M; Matoba, M; Miyano, K; Nodai, T; Ono, K; Uezono, Y; Watanabe, S; Yamaguchi, K | 1 |
| Abreu, MS; Barcellos, LJ; Giacomini, AC; Kalueff, AV | 1 |
| Hattori, T; Hitomi, S; Imai, R; Inenaga, K; Kase, Y; Kubota, K; Omiya, Y; Ono, K; Terawaki, K; Yamaguchi, K | 1 |
| Baba, F; Hacibeyoglu, G; Kiyici, A; Narin, C; Onoglu, R; Sarigul, A; Sarkilar, G | 1 |
| Göktalay, G; Millington, WR | 1 |
| Bali, KK; Gritsch, S; Kuner, R; Vardeh, D | 1 |
| Beck-Schimmer, B; Blyszczuk, P; Eriksson, U; Jakob, P; Kania, G; Krasniqi, N; Müller-Edenborn, B; Osto, E | 1 |
| Chen, S; Lewkowich, IP; Li, AL; Strong, JA; Xie, W; Zhang, JM | 1 |
| Ellrich, J; Feistel, S; Messlinger, K; Nöbel, M | 1 |
| Chen, SB; Hou, BC; Huang, J; Liu, WC; Luo, XL; Wang, XF; Zhan, YP | 1 |
| Chen, Y; DeSimone, J; He, Y; Lu, J; Molokie, RE; Tian, X; Wang, ZJ; Wilkie, DJ; Xiao, C; Yang, C | 1 |
| Calvo, A; Casanova, J; García, C; Garutti, I; Marchal-Duval, E; Paredes, SD; Rancan, L; Rincón, D; Simón, C; Turrero, A; Vara, E | 1 |
| Aceves, M; Grau, JW; Hook, MA; Huang, YJ; Reynolds, JA; Strain, MM; Turtle, JD | 1 |
| Krzemiński, TF; Mitręga, KA; Porc, M; Żorniak, M | 1 |
| Byram, SC; Byram, SW; Fargo, KN; Miller, NM | 1 |
| Bogni, A; Carafa, M; Del Favero, E; Di Marzio, L; Marianecci, C; Paolino, D; Pieretti, S; Ponti, J; Rinaldi, F; Rondelli, V; Rossi, F | 1 |
| Chen, DT; Chen, YH; Li, Q; Pan, JH; Xing, W; Xue, RF; Yan, Y; Yuan, YF; Zeng, WA | 1 |
| Authier, N; Coudoré, F; Decalonne, L; Eschalier, A; Ling, B | 1 |
| Comtois, P; Munoz, M; Nattel, S; Sakabe, M; Shiroshita-Takeshita, A; Texier, A; Vigmond, EJ | 1 |
| d'Avila, A; Dando, JD; Darrow, RD; Dukkipati, SR; Dumoulin, CL; Foo, TK; Fung, M; Guhde, R; Holmvang, G; Kampa, G; Malchano, Z; Mallozzi, R; McPherson, C; Reddy, VY; Ruskin, JN; Schmidt, EJ; Slavin, G | 1 |
| Henry, JL; Pitcher, GM | 1 |
| Benveniste, H; Du, C; Glass, PS; Kritzer, M; Luo, Z; Ma, Y; Smith, SD; Volkow, ND; Yu, M | 1 |
| De Felice, M; Ibrahim, MM; Malan, TP; Mata, HP; Porreca, F; Rivat, C; Stagg, NJ; Vera-Portocarrero, LP | 1 |
| Bjorling, DE; Boldon, K; Bushman, W; Guerios, SD; Wang, ZY | 1 |
| Harada, M; Honjo, H; Ishiguro, YS; Kamiya, K; Kodama, I; Morishima, M; Nakagawa, H; Okuno, Y; Opthof, T; Sakuma, I; Suzuki, T; Takanari, H; Yamazaki, M | 1 |
| Dosdall, DJ | 1 |
| Adjamian, P; Hall, DA; Sereda, M | 1 |
| Abbadie, C; Cook, JJ; Hargreaves, R; Meng, X; Reicin, AS; Ritter, A; Welsh, DC; Williams, DS; Williams, M; Zhao, F | 1 |
| Mizumura, K; Nasu, T; Taguchi, T | 1 |
| Demir, MN; Demir, ZA; Nurözler, AB; Ornek, F; Yalçin Tök, O; Yilmaz, FM; Yilmaz, G | 1 |
| Chen, CL; Chen, JJ; Chiang, RP; Huang, CT; Lin, LH; Lue, JH; Tsai, YJ | 1 |
| Antzelevitch, C; Burashnikov, A; Nof, E | 1 |
| Juszczak, K; Thor, PJ; Wyczolkowski, M; Ziomber, A | 1 |
| Almeida, JP; Batista, IM; Batista, LM; Carvalho, CH; Castro-Costa, CM; Castro-Costa, SB | 1 |
| Lazzara, R | 1 |
| Hajós, M; Hoffmann, WE; Kiss, T | 1 |
| Wang, DF; Xie, JD | 1 |
| Ashcroft, GS; Gilliver, SC; Hardman, MJ; Masterson, GR; Waite, A | 1 |
| Nakazato, Y; Obata, H; Saito, S; Suto, T; Tabata, Y; Tobe, M; Yokoo, H | 1 |
| Aguilar, J; Alonso-Calviño, E; Foffani, G; Humanes-Valera, D; Moxon, KA; Oliviero, A; Yague, JG | 1 |
| Ahmed, R; Habazettl, H; Perschel, FH; Schäfer, M; Schäper, J; Welte, M | 1 |
| Krzemiński, TF; Mitrega, K; Porc, M; Zorniak, M | 1 |
| Cetin, C; Karabaggli, Y; Kiremitci, A; Kocman, E; Kose, AA | 1 |
| Harada, M; Honjo, H; Ishiguro, YS; Kamiya, K; Kodama, I; Nakagawa, H; Okuno, Y; Sakuma, I; Takanari, H; Yamazaki, M | 1 |
| Chang, SM; Wang, X; Yu, GR | 1 |
| Gerner, P; Pancaro, C; Strichartz, G; Wang, CF | 1 |
| Hosaka, Y; Kadomatsu, K; Kadota, S; Shimizu, Y; Takeuchi, K; Tosa, Y; Yokoyama, T | 1 |
| Faggioni, M; Hasdemir, C; Hwang, HS; Knollmann, BC; Laver, D; Mehra, D; Turhan, K; Yin, H | 1 |
| Dalle, C; Gamper, N; Ooi, L; Robertson, B; Rose, K; Wood, IC | 1 |
| Choi, JW; In, JH; Jeon, YS; Joo, JD; Jung, HS; Kim, DW; Kim, YS; Lee, JA; Shin, EY; Yeom, JH | 1 |
| Baron, R; Bartsch, F; Gorodetskaya, N; Grossmann, L; Jänig, W; Kirillova, I; Rausch, VH; Struck, M; Teliban, A; Tode, J | 1 |
| Asano, K; Chancellor, M; Egawa, S; Furuta, A; Honda, M; Koike, Y; Naruoka, T; Suzuki, Y; Yoshimura, N | 1 |
| Butterworth, JF; Wolfe, JW | 1 |
| Gunay, I; Gunes, Y; Mert, T | 1 |
| Eblen-Zajjur, A; Wix-Ramos, R | 1 |
| Adanır, T; Aksun, M; Karabuğa, T; Köseoğlu, M; Nazlı, O; Sencan, A; Yılmaz Karaören, G | 1 |
| Brion, T; Davis, P; Dussor, GO; King, T; Liu, P; Okun, A; Ossipov, MH; Porreca, F; Remeniuk, B; Ren, J; Xie, J | 1 |
| Adães, S; Castro-Lopes, JM; Ferreira-Gomes, J; Mendonça, M | 1 |
| Baltes, C; Bosshard, SC; Grandjean, J; Rudin, M; Schroeter, A; Zeilhofer, HU | 1 |
| Ellis, LD; Soanes, KH | 1 |
| Cheng, J; Fox, LE; Shen, J | 1 |
| Al Amin, HA; Atweh, SF; Barchini, J; Jabbur, SJ; Saadé, NE; Shamaa, F; Tchachaghian, S | 1 |
| Dobson, GP; Letson, HL; Mhango, LP; Pecheniuk, NM | 1 |
| Anjos-Valotta, EA; Arantes, AC; Cordeiro, RS; Cotias, AC; Couto, GC; Ferreira, TP; Jurgilas, PB; Martins, MA; Olsen, PC; Pão, CR; Pires, AL; Serra, MF; Silva, PM | 1 |
| Barlow, P; Bemis, D; Coan, P; Daley, BJ; Goldman, MH; Karlstad, M; Lawson, CM; Newkirk, K; Norwood, J; Sams, VG | 1 |
| Nakazato, Y; Obata, H; Oku, H; Saito, S; Suto, T; Tobe, M; Yokoo, H | 1 |
| Dobson, GP; Frøkiær, J; Granfeldt, A; Hyldebrandt, JA; Nielsen, TK; Sølling, C; Tønnesen, E; Vinten-Johansen, J; Wogensen, L | 1 |
| Proctor, KG; Van Haren, RM | 1 |
| Bean, BP; Brenneis, C; Cobos, EJ; Ferreirós, N; Geisslinger, G; Ghasemlou, N; Kistner, K; Labocha, S; Puopolo, M; Reeh, PW; Roberson, D; Segal, D; Sisignano, M; Strominger, A; Woolf, CJ | 1 |
| Mailman, D | 1 |
| Dabezies, EJ; Graham, S; Henry, BJ; Kenison, M; McVay, C; Rasty, J; Rolfe, R; Slauterbeck, J | 1 |
| Blackburn-Munro, G; Erichsen, HK; Hao, JX; Xu, XJ | 1 |
| Hatori, N; Hinokiyama, K; Maehara, T; Ochi, M; Tanaka, S | 1 |
| Miller, AW; Sims, JJ; Ujhelyi, MR | 1 |
| Del Bel, EA; Prado, WA; Villarreal, CF | 1 |
| Hatakenaka, S; Miyakubo, H; Nomura, M; Tanaka, J | 1 |
| Azoulay, E; Brochard, L; Delclaux, C; Harf, A; Herigault, S; Levame, M; Schlemmer, B | 1 |
| Barrett, TD; Sarraf, G; Walker, MJ | 1 |
| Al-Amin, HA; Apkarian, AV; Atweh, SF; Baliki, M; Hawwa, N; Jabbur, SJ; Jaber, M; Saadé, NE | 1 |
| Apan, A; Kisa, U; Saray, A | 1 |
| Binker, MG; Cosen-Binker, LI; Negri, G; Tiscornia, O | 1 |
| Ashikaga, K; Higuma, T; Iwasa, A; Kimura, M; Kobayashi, T; Motomura, S; Okumura, K; Owada, S; Sasaki, S | 1 |
| Balaraman, V; Easa, D; Egan, E; Huang, TK; Miyasato, CY; Person, D; Uyehara, CF | 1 |
| Ben-Dor, E; Devor, M; Raber, P; Sukhotinsky, I | 1 |
| Capuano-Waters, C; Cottrell, JE; Kass, IS; Lei, B; Popp, S | 1 |
| Marques, MJ; Neto, HS; Pertille, A; Somazz, MC; Teodori, RM | 1 |
| Bertelli, JA; Calixto, JB; Campos, MM; Ferreira, J; Rodrigues-Filho, R; Santos, AR | 1 |
| Kina, VA; Prado, WA; Villarreal, CF | 1 |
| Chevalier, E; Chovet, M; Langlois, A; Pétoux, F | 1 |
| Cristea, M; Kolesnikov, Y; Oksman, G; Torosjan, A; Wilson, R | 1 |
| Imaki, R; Inuo, K; Izumi, T; Morohoshi, Y; Nakayama, S; Niwano, S; Yuge, M | 1 |
| Dey, DD; Landrum, O; Oaklander, AL | 1 |
| Radhakrishnan, R; Skyba, DA; Sluka, KA | 1 |
| Barros, SP; Oliveira, MC; Parada, CA; Rodrigues, LR; Tambeli, CH; Veiga, MC | 1 |
| Bozeman, WP; Idris, AH | 1 |
| Hashimoto, K; Honsho, S; Nakamura, Y; Sugiyama, A; Takahara, A | 1 |
| Lauritzen, B; Lykkegaard, K; Svendsen, O; Tessem, L; Weikop, P | 1 |
| Higashi, H; Kuroiwa, M; Murai, Y; Niiyama, S; Noguchi, M; Sakamoto, H; Satani, M; Takahashi, K; Tanaka, E; Tsuji, S; Yamada, A | 1 |
| Cassuto, J; Jodal, M; Lundgren, O; Tuttle, R | 1 |
| Huda, K; Imoto, K; Inoue, T; Miyata, M; Sasaki, S | 1 |
| Aiba, T; Hidaka, I; Inagaki, M; Kamiya, A; Noda, T; Shimizu, W; Sugimachi, M; Sunagawa, K; Uemura, K; Zheng, C | 1 |
| Evdokimova, NR; Gavrovskaya, LK; Krylova, IB; Sapronov, NS | 1 |
| King, T; Kowal, J; Ossipov, MH; Porreca, F; Vera-Portocarrero, LP; Xie, JY; Yie, JX | 1 |
| Biella, GE; Caramenti, GC; Sotgiu, ML; Valente, M | 1 |
| Doya, H; Inoue, G; Ito, T; Koshi, T; Moriya, H; Ohtori, S; Saito, T; Takahashi, K | 1 |
| Black, YD; Di Pietro, NC; Kantak, KM | 1 |
| Crown, ED; Hulsebosch, CE; McAdoo, DJ; Rooney, BA | 1 |
| Morita, H; Morita, ST; Wu, J; Zipes, DP | 1 |
| Deschênes, I; Laurita, KR | 1 |
| Menegazzi, JJ; Reynolds, JC; Rittenberger, JC | 1 |
| Itoh, H; Kurachi, M; Matsuoka, T; Sumiyoshi, T; Uehara, T | 1 |
| Kim, JH; Lee, SE | 1 |
| Ayoub, IM; Gazmuri, RJ; Kolarova, JD; Radhakrishnan, J; Taglieri, DM; Wang, S | 1 |
| Marques, MJ; Minatel, E; Neto, HS; Taniguti, AP | 1 |
| Gu, MN; Lin, CS; Liu, YY; Ruan, LY | 1 |
| Bourghardt Peebo, B; Fagerholm, P; Gan, L; Knutsen, A; Rearden, A; Sun, XF | 1 |
| Lim, TK; Macleod, BA; Ries, CR; Schwarz, SK | 1 |
| Grace, AA; Huang, CL; Li, LM; Sabir, IN | 1 |
| Feng, G; Liu, GJ; Liu, S; Wang, GL | 1 |
| Ferchichi, H; Klouz, A; Kourda, N; Lakhal, M; Morin, D; Ouanes, L; Saïd, DB; Tillement, JP | 1 |
| Gu, YW; Su, DS; Tian, J; Wang, XR | 1 |
| Rudick, CN; Schaeffer, AJ; Thumbikat, P | 1 |
| Inoue, H; Mashima, S; Matsuo, H; Murao, S | 1 |
| Banitt, EH; Kvam, DC; Schmid, JR | 1 |
| Bogoiavlenskaia, TA; Danilov, MA; Kirpatovskiĭ, VI; Lubiako, AA; Onishchenko, NA | 1 |
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| Koltai, M; Leprán, I; Siegmund, W; Szekeres, L | 1 |
| Borerwe, TA; Evans, EF; Wilson, JP | 1 |
| Bergey, JL; McCallum, JD; Nocella, K | 1 |
| Fukuzaki, H; Hatani, M; Hori, Y; Imai, N; Nadai, T; Okamoto, R; Takano, S; Toh, H | 1 |
| Adams, D; Lixfeld, W; Shum, A; Sole, MJ | 1 |
| Haruna, M; Kimoto, S; Nakao, T; Ueda, M | 1 |
| Calabro, J; Ettinger, PO; Moore, RJ; Oldewurtel, HA; Regan, TJ | 1 |
| Campos, CJ; Cavalheiro, EA | 1 |
| Clark, C; Foreman, MI; Kane, KA; McDonald, FM; Parratt, JR | 1 |
| Marshall, RJ; Parratt, JR | 1 |
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| Aupetit, JF; Barral-Cadière, L; Faucon, G; Freysz, M; Lopez, M; Loufoua-Moundanga, J; Timour, Q | 1 |
| Castagna, A; Lacerenza, M; Marchettini, P; Sotgiu, ML | 1 |
| Igbo, IN; Onuaguluchi, G | 1 |
| Sluka, KA; Westlund, KN | 1 |
| Eimerl, D; Haskel, Y; Schiffman, J; Udassin, R | 1 |
| Bardin, M; Chantelauze, C; Courteix, C; Eschalier, A; Lavarenne, J | 1 |
| Armstrong, JM; Bellemin-Baurreau, J; Hicks, PE; Poizot, A | 1 |
| Karatassas, A; Morris, RG; Slavotinek, AH | 1 |
| Anastasiou-Nana, MI; Moulopoulos, SD; Nanas, JN; Nanas, SN; Poyadjis, A; Rapti, A; Stathaki, S | 1 |
| Chow, MS; Fan, C; Kluger, J; O'Rangers, EA; Ujhelyi, MR | 1 |
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| Cerra, FB; Hu, MY; Hu, WS; Mann, HJ; Nyberg, SL; Payne, WD; Remmel, RP | 1 |
| Behnia, R; Koushanpour, E; Sinclair, DM | 1 |
| Hämäläinen, MM; Pertovaara, A; Wei, H | 1 |
| Bruyninckx, FL; Marcus, MA; Van Aken, H; Vertommen, JD; Wouters, PF | 1 |
| Manabe, Y; Oka, H; Saito, H; Yoshida, S | 1 |
| Jund, R; Kastenbauer, E | 1 |
| Agrawal, SK; Fehlings, MG | 1 |
| Kuraoka, F; Kuroiwa, A; Murasato, Y; Nagamoto, Y; Nakashima, Y; Urabe, T | 1 |
| Allessie, M; Anvari, A; Mast, F; Schmidinger, H; Schuster, E | 1 |
| Bardakhch'ian , EA; Kharlanova, NG; Lomov, IM | 1 |
| Kaga, K; Sakata, H; Tsuzuku, T; Uno, A; Yamada, K | 1 |
| Coutts, RT; Jewell, LD; Tam, YK; Zaman, N | 1 |
| Cromeens, D; Evans, GR; Gherardini, G; Gürlek, A; Joly, GA; Wang, BG | 1 |
| Goldstein, S; Lesch, M; Maltsev, VA; Sabbah, HN; Tanimura, M; Undrovinas, AI | 1 |
| de Curtis, M; Forti, M; Radici, C | 1 |
| Baumgarten, KM; Gerstenblith, G; Weiss, RG | 1 |
| Blisard, KS; Follis, FM; Pett, SB; Temes, RT; Varvitsiotis, PS; Wernly, JA | 1 |
| Kiyonari, Y; Maekawa, N; Mikawa, K; Nishina, K; Obara, H | 1 |
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| Hayashi, Y; Hidaka, T; Inomata, N; Inoue, T; Komoriya, K | 1 |
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| Amir, A; Barness, I; Chapman, S; Fishbeine, E; Kadar, T; Liani, H; Meshulam, Y; Sahar, R | 1 |
| Ishii, T; Kaneko, H; Katagiri, M; Maeda, T; Otsuka, Y; Shiba, T; Takagi, S; Tamura, A; Tsuchiya, M | 1 |
| Baba, JS; Cameron, BD; Coté, GL | 1 |
| Bertram, EH; Mangan, PS; Scott, CA; Williamson, JM; Zhang, D | 1 |
| Kikuchi, S; Myers, RR; Onda, A; Satoh, K; Yabuki, S | 1 |
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| Bazzani, C; Bertolini, A; Cainazzo, MM; Ferrazza, G; Guarini, S; Mioni, C | 1 |
| Black, Y; Eichenbaum, HB; Green-Jordan, K; Kantak, KM; Valencia, E | 2 |
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| Blecic, S; Contempré, B; Reuse, C; Vachiery, JL; Vincent, JL | 1 |
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| Iwai, K; Kudoh, D; Nishiki, K; Nishinaga, K | 1 |
| Iwai, K; Kudoh, D; Nakagawa, H; Nishiki, K; Nishinaga, K | 1 |
| Parnes, SM; Spektor, Z; Strominger, N | 1 |
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| Inoue, H; Mashima, S; Matsuo, H; Murao, S; Sugimoto, T | 1 |
| Doppman, JL; Girton, M; Oldfield, EH | 1 |
| Heapy, CG; O'Neill, PA; Russell, NJ; Stark, RD; Stretton, TB | 1 |
| Geter, RK; Puckett, CL; Winters, RR | 1 |
| Schwartz, PJ; Vanoli, E; Zaza, A; Zuanetti, G | 1 |
| Inoue, H; Mashima, S; Matsuo, H; Nozaki, A; Sugimoto, T; Toda, I | 1 |
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| Chiale, P; Elizari, MV; Halpern, MS; Lázzari, JO; Levi, RJ; Nau, GJ; Novakovsky, A; Rosenbaum, MB | 1 |
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| Baum, T; Eckfeld, DK; Rowles, G; Shropshire, AT; Varner, LL | 1 |
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12 review(s) available for lidocaine and Disease Models, Animal
| Article | Year |
|---|---|
Mechanistic considerations for adenosine-lidocaine-magnesium (ALM) in controlling coagulopathy.
Topics: Adenosine; Animals; Disease Models, Animal; Humans; Lidocaine; Magnesium; Shock, Hemorrhagic; Swine | 2023 |
The mechanisms of tinnitus: perspectives from human functional neuroimaging.
Topics: Action Potentials; Animals; Auditory Cortex; Disease Models, Animal; Electroencephalography; Electrophysiological Phenomena; Humans; Lidocaine; Magnetoencephalography; Models, Neurological; Perceptual Masking; Tinnitus | 2009 |
Local anesthetic systemic toxicity: update on mechanisms and treatment.
Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular Diseases; Disease Models, Animal; Epinephrine; Fat Emulsions, Intravenous; Humans; Lidocaine; Neurotoxicity Syndromes; Vasoconstrictor Agents; Vasopressins | 2011 |
Drug administration in animal studies of cardiac arrest does not reflect human clinical experience.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Clinical Trials as Topic; Disease Models, Animal; Drug Administration Schedule; Epinephrine; Heart Arrest; Humans; Lidocaine; Life Support Care; Magnesium Sulfate; Regression Analysis; Sodium Bicarbonate; Time Factors; Vasoconstrictor Agents; Vasopressins | 2007 |
Animal models of tinnitus.
Topics: Acoustic Stimulation; Action Potentials; Aged; Animals; Cats; Cochlear Nerve; Disease Models, Animal; Ear, Middle; Guinea Pigs; Humans; Lidocaine; Oxygen; Pressure; Salicylates; Time Factors; Tinnitus | 1981 |
Lidocaine for acute lung injury: questions still to answer.
Topics: Animals; Critical Illness; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Inflammation; Lidocaine; Neutrophils; Phospholipases A; Rabbits; Respiratory Distress Syndrome; Trypsin | 2000 |
Potential neurotoxicity of spinal anesthesia with lidocaine.
Topics: Adverse Drug Reaction Reporting Systems; Anesthesia, Spinal; Anesthetics, Local; Animals; Bupivacaine; Disease Models, Animal; Humans; Incidence; Lidocaine; Pain; Radiculopathy; Risk Factors; Spinal Nerves; Tetracaine | 2000 |
Advanced cardiac life support antiarrhythmic drugs.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Bretylium Compounds; Cardiopulmonary Resuscitation; Clinical Trials as Topic; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Heart Arrest; Humans; Lidocaine; Life Support Care; Magnesium; Male; Procainamide; Treatment Outcome | 2002 |
Clinical relevance of experimentally obtained electrophysiologic data on antiarrhythmic drugs.
Topics: Animals; Anti-Arrhythmia Agents; Coronary Disease; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Electrophysiology; Heart; Humans; Lidocaine; Tachycardia | 1979 |
Endotracheal drug delivery.
Topics: Animals; Atropine; Cardiopulmonary Resuscitation; Disease Models, Animal; Epinephrine; Humans; Intubation, Intratracheal; Lidocaine; Naloxone; Pediatrics | 1992 |
[Compounds with antiarrhythmic effects].
Topics: Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Animals, Laboratory; Anti-Arrhythmia Agents; Antidepressive Agents; Antimalarials; Arrhythmias, Cardiac; Chemical Phenomena; Chemistry; Disease Models, Animal; Histamine H1 Antagonists; Lidocaine; Procainamide; Quinidine; Structure-Activity Relationship | 1973 |
Cerebral arterial spasm: current concepts.
Topics: Anesthesia, General; Animals; Blood Coagulation; Blood Platelets; Brain; Catecholamines; Cerebral Arterial Diseases; Cerebral Arteries; Disease Models, Animal; Dogs; Humans; Intracranial Aneurysm; Intracranial Pressure; Isoproterenol; Lidocaine; Nerve Block; Norepinephrine; Prostaglandins; Receptors, Adrenergic; Receptors, Cholinergic; Reserpine; Spasm; Subarachnoid Hemorrhage; Sympathectomy; Sympathetic Nervous System; Time Factors | 1974 |
2 trial(s) available for lidocaine and Disease Models, Animal
| Article | Year |
|---|---|
Effects of a Lidocaine-Loaded Poloxamer/Alginate/CaCl2 Mixture on Postoperative Pain and Adhesion in a Rat Model of Incisional Pain.
Topics: Alginates; Anesthetics, Local; Animals; Anti-Inflammatory Agents; Behavior, Animal; Calcium Chloride; Disease Models, Animal; Glucuronic Acid; Hexuronic Acids; Lidocaine; Linear Models; Male; Multivariate Analysis; Pain Measurement; Pain, Postoperative; Poloxamer; Rats; Rats, Sprague-Dawley; Tissue Adhesions; Treatment Outcome | 2017 |
Effects of small-particle aerosols of local anaesthetic on dyspnoea in patients with respiratory disease.
Topics: Aerosols; Aged; Animals; Clinical Trials as Topic; Disease Models, Animal; Drug Evaluation, Preclinical; Dyspnea; Female; Humans; Lidocaine; Lung Diseases, Obstructive; Male; Middle Aged; Particle Size; Pulmonary Embolism; Rats; Respiration; Respiratory Tract Diseases; Solutions | 1985 |
328 other study(ies) available for lidocaine and Disease Models, Animal
| Article | Year |
|---|---|
4,5-Dihydro-1-phenyl-1H-2,4-benzodiazepines: novel antiarrhythmic agents.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzodiazepines; Cats; Disease Models, Animal; Dogs; Guinea Pigs; Heart Ventricles; Male; Myocardial Contraction; Myocardial Infarction; Potassium Channels; Rats; Rats, Sprague-Dawley; Refractory Period, Electrophysiological; Sodium Channels; Structure-Activity Relationship | 1993 |
Synthesis of new N-benzylpiperidine derivatives as cholinesterase inhibitors with β-amyloid anti-aggregation properties and beneficial effects on memory in vivo.
Topics: Acetylcholinesterase; Alzheimer Disease; Amnesia; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Disease Models, Animal; Donepezil; Humans; Indans; Indoles; Male; Memory; Mice; Models, Molecular; Neuroprotective Agents; Phthalimides; Piperidines; Protein Aggregates; Scopolamine; Structure-Activity Relationship | 2015 |
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, Spinal; Humans; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pruritus; Receptors, Atrial Natriuretic Factor; Reproducibility of Results; Signal Transduction; Small Molecule Libraries | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
ALM Fluid Therapy Shifts Sympathetic Hyperactivity to Parasympathetic Dominance in the Rat Model of Non-Compressible Hemorrhagic Shock.
Topics: Adenosine; Animals; Disease Models, Animal; Drug Combinations; Fluid Therapy; Lidocaine; Magnesium; Male; Parasympathetic Nervous System; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic; Sympathetic Nervous System | 2022 |
Adenosine, lidocaine, and magnesium for attenuating ischemia reperfusion injury from resuscitative endovascular balloon occlusion of the aorta in a porcine model.
Topics: Adenosine; Animals; Aorta; Balloon Occlusion; Disease Models, Animal; Endovascular Procedures; Hemorrhage; Lidocaine; Magnesium; Reperfusion Injury; Shock, Hemorrhagic; Swine | 2022 |
Phrenic Nerve Block and Respiratory Effort in Pigs and Critically Ill Patients with Acute Lung Injury.
Topics: Acute Lung Injury; Animals; Critical Illness; Disease Models, Animal; Female; Humans; Lidocaine; Phrenic Nerve; Respiration, Artificial; Respiratory Distress Syndrome; Respiratory Mechanics; Swine; Tidal Volume | 2022 |
Neuroprotective Effects of a Cardioplegic Combination (Adenosine, Lidocaine, and Magnesium) in an Ischemic Stroke Model.
Topics: Adenosine; Animals; Cardioplegic Solutions; Cobalt; Disease Models, Animal; Glucose; Humans; Ischemic Stroke; Lidocaine; Magnesium; Neuroblastoma; Neuroprotective Agents; Oxygen; Rats; Stroke | 2022 |
Experimental Study of Tumescence Injection to Provide Anesthesia Without Local Anesthetics.
Topics: Anesthesia, Local; Anesthetics, Local; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Epinephrine; Injections, Subcutaneous; Lidocaine; Male; Mice; Pain; Pain Measurement; Surgical Procedures, Operative | 2020 |
Analysis of Epineurial Lidocaine Injection for Nerve Transfers in a Rat Sciatic Nerve Model.
Topics: Animals; Calcium Gluconate; Disease Models, Animal; Injections; Lidocaine; Nerve Transfer; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Time Factors | 2019 |
Lung Purinoceptor Activation Triggers Ventilator-Induced Brain Injury.
Topics: Anesthetics, Local; Animals; Brain Injuries; Cell Line; Disease Models, Animal; Hippocampus; Humans; Lidocaine; Lung; Magnetic Resonance Imaging; Mice, Inbred C57BL; Purinergic P2X Receptor Antagonists; Receptors, Purinergic P2X; Respiration, Artificial; Tidal Volume; TRPV Cation Channels | 2019 |
Effects of 1% Lidocaine Instillation on Overactive Bladder Induced by Bladder Outlet Obstruction in Rats.
Topics: Administration, Intravesical; Anesthetics, Local; Animals; Disease Models, Animal; Female; Lidocaine; Rats; Rats, Sprague-Dawley; Urinary Bladder Neck Obstruction; Urinary Bladder, Overactive | 2020 |
Novel charged sodium and calcium channel inhibitor active against neurogenic inflammation.
Topics: Animals; Bupivacaine; Calcium; Calcium Channel Blockers; Calcium Channels, N-Type; Calcium Signaling; Disease Models, Animal; Ganglia, Spinal; Humans; Lidocaine; Mice; Neurogenic Inflammation; Nociceptors; Pain; Sodium Channel Blockers; Sodium Channels | 2019 |
Combination Formulation of Tetrodotoxin and Lidocaine as a Potential Therapy for Severe Arrhythmias.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Drug Combinations; Drug Stability; Excipients; Female; Freeze Drying; Lidocaine; Male; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Tetrodotoxin; Voltage-Gated Sodium Channel Blockers | 2019 |
The morphofunctional impact of topical Lidocaine formulation in inflammatory pain - experimental study.
Topics: Administration, Topical; Anesthetics, Local; Animal Experimentation; Animals; Disease Models, Animal; Humans; Inflammation; Lidocaine; Male; Rats; Rats, Wistar | 2019 |
Sustained Release of Levobupivacaine, Lidocaine, and Acemetacin from Electrosprayed Microparticles: In Vitro and In Vivo Studies.
Topics: 3T3 Cells; Analgesics; Animals; Delayed-Action Preparations; Disease Models, Animal; Drug Compounding; Femoral Fractures; Fractures, Bone; Indomethacin; Levobupivacaine; Lidocaine; Mice; Microtechnology; Molecular Structure; Pain; Particle Size; Rats; Spectrometry, Mass, Electrospray Ionization | 2020 |
Adenosine, Lidocaine, and Magnesium Support a High Flow, Hypotensive, Vasodilatory State With Improved Oxygen Delivery and Cerebral Protection in a Pig Model of Noncompressible Hemorrhage.
Topics: Adenosine; Animals; Brain; Brain Chemistry; Disease Models, Animal; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluid Therapy; Glycerol; Humans; Hypotension; Hypoxia-Inducible Factor 1, alpha Subunit; Hypoxia, Brain; Infusions, Intravenous; Injections, Intravenous; Lactic Acid; Lidocaine; Liver; Magnesium; Oxygen; Resuscitation; Shock, Hemorrhagic; Stroke Volume; Sus scrofa; Vascular Resistance; Vasodilation | 2020 |
Effects of 2-Hydroxypropil-Β-Cyclodextrin-Lidocaine on Tumor Growth and Inflammatory Response.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Animals; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chemokine CXCL1; Disease Models, Animal; Drug Carriers; Drug Compounding; Drug Screening Assays, Antitumor; Edema; HaCaT Cells; Humans; Inflammation; Interleukin-1alpha; Lidocaine; Male; Neoplasms; Rats; Rats, Wistar; Signal Transduction; Tumor Necrosis Factor-alpha | 2020 |
Buprenorphine Analgesia Reduces Survival With ALM Resuscitation in a Rat Model of Uncontrolled Hemorrhage: Concerns for Trauma-Related Research.
Topics: Adenosine; Analgesia; Analgesics, Opioid; Animals; Biomedical Research; Buprenorphine; Disease Models, Animal; Hemorrhage; Lidocaine; Magnesium; Male; Random Allocation; Rats; Rats, Sprague-Dawley; Resuscitation; Survival Rate; Wounds and Injuries | 2021 |
Downregulation of microRNA-199a-5p alleviated lidocaine-induced sensory dysfunction and spinal cord myelin lesions in a rat model.
Topics: Animals; Antagomirs; Disease Models, Animal; Down-Regulation; Lidocaine; Male; MicroRNAs; Myelin Sheath; Neurotoxicity Syndromes; Pain Threshold; Rats, Sprague-Dawley; Sensation Disorders; Spinal Cord; Spinal Cord Diseases; Transcription Factors | 2021 |
Methylene blue induces an analgesic effect by significantly decreasing neural firing rates and improves pain behaviors in rats.
Topics: Action Potentials; Analgesics; Animals; Coloring Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Femoral Nerve; Hindlimb; Lidocaine; Male; Methylene Blue; Neural Inhibition; Neurons; Pain; Rats; Rats, Sprague-Dawley | 2021 |
Therapeutic cardiac arrest as an adjunct to resuscitative endovascular balloon occlusion of the aorta: Bridging the gap from fatal hemorrhage to definitive surgical control in swine.
Topics: Adenosine; Animals; Aorta; Balloon Occlusion; Cardioplegic Solutions; Cardiovascular Agents; Disease Models, Animal; Endovascular Procedures; Exsanguination; Heart Arrest, Induced; Hemostasis, Surgical; Lidocaine; Magnesium; Pharmaceutical Solutions; Preoperative Care; Resuscitation; Swine | 2021 |
Postinjury treatments to make early tactical aeromedical evacuation practical for the brain after TBI.
Topics: Adenosine; Air Ambulances; Allopurinol; Amitriptyline; Animals; Brain; Brain Chemistry; Brain Injuries, Traumatic; Cytokines; Disease Models, Animal; Emergency Medical Services; Lidocaine; Magnesium; Male; Mice; Mice, Inbred C57BL; Propranolol; Rotarod Performance Test | 2021 |
The Effect of Lidocaine and Bosutinib on 4T1 Murine Breast Cancer Cell Behaviour
Topics: Aniline Compounds; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Survival; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Female; Lidocaine; Mice; Neoplasm Metastasis; Nitriles; Quinolines | 2021 |
Lidocaine prevents breast cancer growth by targeting neuronatin to inhibit nerve fibers formation.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; Female; Humans; Lidocaine; Male; Mice; Neoplasm Metastasis; Nerve Fibers; Nerve Tissue Proteins | 2021 |
Pharmacologic Inhibition of Pain Response to Incomplete Vascular Occlusion Blunts Cardiovascular Preconditioning Response.
Topics: Anesthetics, Local; Animals; Cytokines; Disease Models, Animal; Echocardiography; Forelimb; Ischemic Preconditioning; Lidocaine; Ligation; Male; Mice, Inbred C57BL; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Pain Threshold; Radial Artery; Regional Blood Flow; Time Factors | 2021 |
Combatting ischemia reperfusion injury from resuscitative endovascular balloon occlusion of the aorta using adenosine, lidocaine and magnesium: A pilot study.
Topics: Adenosine; Animals; Anti-Inflammatory Agents; Aorta; Balloon Occlusion; Disease Models, Animal; Drug Therapy, Combination; Endovascular Procedures; Hydrogen-Ion Concentration; Lactic Acid; Lidocaine; Magnesium; Protective Agents; Reperfusion Injury; Resuscitation; Shock, Hemorrhagic; Swine; Treatment Outcome | 2021 |
Effects of Treadmill Exercise on Advanced Osteoarthritis Pain in Rats.
Topics: Anesthetics, Local; Animals; Arthralgia; Arthritis, Experimental; Behavior, Animal; Disease Models, Animal; Enzyme Inhibitors; Hyperalgesia; Injections, Intra-Articular; Iodoacetic Acid; Knee Joint; Lidocaine; Male; Medulla Oblongata; Naloxone; Narcotic Antagonists; Osteoarthritis, Knee; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley; Tibia; Weight-Bearing; X-Ray Microtomography | 2017 |
Lidocaine Prevents Oxidative Stress-Induced Endothelial Dysfunction of the Systemic Artery in Rats With Intermittent Periodontal Inflammation.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Aorta; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Gingiva; Inflammation Mediators; Injections; Lidocaine; Lipopolysaccharides; Male; NADPH Oxidases; Oxidative Stress; Periodontitis; Rats, Wistar; Reactive Oxygen Species; Time Factors; Tumor Necrosis Factor-alpha; Vasodilation; Vasodilator Agents | 2017 |
[Neuroprotection Mechanism of Lidocaine in Rabbits with Early Brain Injury Resulted from Subarachnoid Hemorrhage].
Topics: Animals; Caspase 3; Disease Models, Animal; Electron Transport Complex IV; Lidocaine; Neuroprotective Agents; Rabbits; Random Allocation; Subarachnoid Hemorrhage | 2017 |
[Comparison of Two Methods of Lidocaine Administrating for Neuroprotection in Rabbit Model of Subarachnoid Hemorrhage].
Topics: Administration, Intravenous; Animals; Basilar Artery; Cisterna Magna; Disease Models, Animal; Injections; Interleukin-6; Lidocaine; Neuroprotection; Rabbits; Subarachnoid Hemorrhage | 2017 |
Immune-inflammatory activation after a single laparotomy in a rat model: effect of adenosine, lidocaine and Mg
Topics: Adenosine; Alkalosis, Respiratory; Animals; Blood Coagulation; Blood Platelets; Complex Mixtures; Disease Models, Animal; Fibrinolysis; Humans; Immunity, Innate; Inflammation; Infusions, Intravenous; Interleukin-10; Interleukin-6; Laparotomy; Lidocaine; Magnesium; Male; Neutrophils; Postoperative Complications; Rats; Rats, Sprague-Dawley | 2017 |
An Intraplantar Hypertonic Saline Assay in Mice for Rapid Screening of Analgesics.
Topics: Analgesics; Analgesics, Opioid; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Injections; Lidocaine; Male; Mice; Morphine; Pain; Pain Measurement; Receptors, Opioid, mu; Saline Solution, Hypertonic; Sodium Chloride | 2018 |
Cardioprotection induced in a mouse model of neuropathic pain via anterior nucleus of paraventricular thalamus.
Topics: Animals; Butadienes; Chronic Pain; Disease Models, Animal; Enzyme Inhibitors; Ganglionic Blockers; Heart Rate; Hexamethonium; Lidocaine; Male; Mice, Inbred C57BL; Midline Thalamic Nuclei; Myocardial Infarction; Myocardial Reperfusion Injury; Neuralgia; Nitriles; Optogenetics | 2017 |
Effects of Extracorporeal Shock Wave-Mediated Transdermal Local Anesthetic Drug Delivery on Rat Caudal Nerves.
Topics: Administration, Cutaneous; Anesthetics, Local; Animals; Disease Models, Animal; Extracorporeal Shockwave Therapy; Lidocaine; Lidocaine, Prilocaine Drug Combination; Male; Pain; Prilocaine; Rats; Rats, Wistar; Tail | 2018 |
Menthol reduces phototoxicity pain in a mouse model of photodynamic therapy.
Topics: Acrylamides; Animals; Animals, Newborn; Antipruritics; Bridged Bicyclo Compounds, Heterocyclic; Dermatitis, Phototoxic; Disease Models, Animal; Evoked Potentials; HEK293 Cells; Humans; Hyperalgesia; Lidocaine; Lipid Metabolism; Menthol; Mice; Mice, Inbred C57BL; Neurons; Pain; Pain Threshold; Photochemotherapy; Reactive Oxygen Species; TRPV Cation Channels | 2018 |
Dexmedetomidine Increases the Latency of Thermal Antinociception in Rats.
Topics: Acute Pain; Adrenergic alpha-2 Receptor Agonists; Anesthetics, Local; Animals; Dexmedetomidine; Disease Models, Animal; Drug Therapy, Combination; Epinephrine; Injections; Lidocaine; Male; Rats; Rats, Wistar; Time Factors | 2017 |
Pharmacodynamics and Pharmacokinetics of Lidocaine in a Rodent Model of Diabetic Neuropathy.
Topics: Anesthetics, Local; Animals; Diabetic Neuropathies; Disease Models, Animal; Lidocaine; Male; Nerve Block; Rats; Sciatic Nerve | 2018 |
Disease modifying actions of interleukin-6 blockade in a rat model of bone cancer pain.
Topics: Adenocarcinoma; Analgesics; Analysis of Variance; Anesthetics, Local; Animals; Bone Neoplasms; Bufanolides; Cancer Pain; Disease Models, Animal; Drug Delivery Systems; Female; Hyperalgesia; Interleukin-6; Lidocaine; Pain Measurement; Radiography; Rats; Rats, Inbred F344; Signal Transduction; STAT3 Transcription Factor | 2018 |
Tumescent contravenom: murine model for prehospital treatment of Naja naja neurotoxic snake envenomation.
Topics: Animals; Antivenins; Disease Models, Animal; Epinephrine; Female; Humans; Injections, Subcutaneous; Kaplan-Meier Estimate; Lidocaine; Mice; Naja naja; Neurotoxicity Syndromes; Pilot Projects; Random Allocation; Sensitivity and Specificity; Snake Bites; Snake Venoms | 2018 |
Adenosine, lidocaine, and Mg2+ (ALM) resuscitation fluid protects against experimental traumatic brain injury.
Topics: Adenosine; Animals; Brain Injuries, Traumatic; Disease Models, Animal; Disease Progression; Fluid Therapy; Lidocaine; Magnesium; Male; Random Allocation; Rats; Rats, Sprague-Dawley; Resuscitation | 2018 |
HIV-1 Tat-induced diarrhea is improved by the PPARalpha agonist, palmitoylethanolamide, by suppressing the activation of enteric glia.
Topics: Amides; Anesthetics, Local; Animals; Antiviral Agents; Diarrhea; Disease Models, Animal; Ethanolamines; Gastrointestinal Tract; Gene Expression Regulation, Viral; Lidocaine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuroglia; NF-kappa B; Palmitic Acids; PPAR alpha; Rats; Rats, Wistar; S100 Calcium Binding Protein beta Subunit; tat Gene Products, Human Immunodeficiency Virus | 2018 |
Nebulized lidocaine ameliorates allergic airway inflammation via downregulation of TLR2.
Topics: Administration, Inhalation; Animals; Disease Models, Animal; Down-Regulation; Female; Inflammation; Lidocaine; Mice; Mice, Inbred C57BL; Nebulizers and Vaporizers; Respiratory Hypersensitivity; Signal Transduction; Toll-Like Receptor 2 | 2018 |
Involvement of dopamine system in the regulation of the brain corticotropin-releasing hormone in paraventricular nucleus in a rat model of chronic visceral pain.
Topics: Animals; Animals, Newborn; Central Nervous System Agents; Chronic Pain; Corticotropin-Releasing Hormone; Depression; Disease Models, Animal; Dopamine; Lidocaine; Male; Paraventricular Hypothalamic Nucleus; Random Allocation; Rats, Sprague-Dawley; RNA Interference; Ventral Tegmental Area; Visceral Pain | 2018 |
Ciprofloxacin-lidocaine-based hydrogel: development, characterization, and in vivo evaluation in a second-degree burn model.
Topics: Administration, Topical; Animals; Burns; Ciprofloxacin; Disease Models, Animal; Hydrogels; Lidocaine; Male; Rabbits; Rheology; Treatment Outcome; Wound Healing | 2018 |
Corticotropin-Releasing Factor in the Brain and Blocking Spinal Descending Signals Induce Hyperalgesia in the Latent Sensitization Model of Chronic Pain.
Topics: Analgesics, Opioid; Animals; Brain; Central Nervous System Sensitization; Chronic Pain; Corticotropin-Releasing Hormone; Disease Models, Animal; Efferent Pathways; Freund's Adjuvant; Hyperalgesia; Lidocaine; Male; Rats; Rats, Sprague-Dawley; Spinal Cord | 2018 |
Topically Delivered Minocycline Penetrates a Full-Thickness Burn Eschar and Reduces Tissue Bacterial Counts.
Topics: Administration, Topical; Anesthetics, Local; Animals; Anti-Bacterial Agents; Bacterial Load; Burns; Debridement; Disease Models, Animal; Female; Lidocaine; Methicillin-Resistant Staphylococcus aureus; Minocycline; Staphylococcal Infections; Swine; Wound Healing; Wound Infection | 2018 |
Effect of four local anesthetics (tetracaine, proparacaine, lidocaine, and bupivacaine) on intraocular pressure in dogs.
Topics: Administration, Topical; Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Disease Models, Animal; Dogs; Female; Glaucoma; Intraocular Pressure; Lidocaine; Male; Propoxycaine; Tetracaine | 2019 |
Basolateral amygdalar inactivation blocks chronic stress-induced lamina-specific reduction in prefrontal cortex volume and associated anxiety-like behavior.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Anxiety; Avoidance Learning; Basolateral Nuclear Complex; Chronic Disease; Disease Models, Animal; Electroshock; Excitatory Amino Acid Agonists; Ibotenic Acid; Lidocaine; Male; Prefrontal Cortex; Rats; Rats, Wistar; Stress, Psychological | 2019 |
Effects of an Intraparenchymal Injection of Lidocaine in the Rat Cervical Spinal Cord.
Topics: Anesthetics, Local; Animals; Cervical Vertebrae; Disease Models, Animal; Injections, Spinal; Lidocaine; Male; Neurons; Rats, Sprague-Dawley; Spinal Cord | 2018 |
Evaluating the Effects of a Topical Preparation with Dexpanthenol, Silbiol, Undecylenic Acid, and Lidocaine on Palatal Mucosa Wound Healing in a Rat Model
Topics: Administration, Topical; Animals; Disease Models, Animal; Drug Combinations; Lidocaine; Palate; Pantothenic Acid; Plant Extracts; Rats; Rats, Sprague-Dawley; Undecylenic Acids; Wound Healing | 2019 |
[Effects of Lidocaine on the Rho/ROCK Signal Transduction of the Posterior Basilar Artery in Rabbit SAH].
Topics: Animals; Basilar Artery; Calmodulin; Disease Models, Animal; Lidocaine; Myosin Light Chains; Rabbits; rho-Associated Kinases; Signal Transduction; Subarachnoid Hemorrhage; Vasospasm, Intracranial | 2018 |
Comparison of antinociceptive effects of plain lidocaine versus lidocaine complexed with hydroxypropyl-β-cyclodextrin in animal models of acute and persistent orofacial pain.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Analgesics; Animals; Capsaicin; Carrageenan; Disease Models, Animal; Formaldehyde; Hot Temperature; Hyperalgesia; Lidocaine; Male; Pain; Rats, Wistar | 2019 |
Lidocaine protects neurons of the spinal cord in an excitotoxicity model.
Topics: Animals; Disease Models, Animal; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; Lidocaine; Male; Neurons; Neuroprotective Agents; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries | 2019 |
Reversing Effect of Insulin on Local Anesthetics-Induced Sciatic Nerve Block in Rats.
Topics: Anesthesia, Local; Animals; Bupivacaine; Disease Models, Animal; Drug Combinations; Humans; Insulin; Lidocaine; Nerve Block; Rats; Sciatic Nerve; Sciatic Neuropathy | 2019 |
Prehospital adenosine, lidocaine, and magnesium has inferior survival compared with tactical combat casualty care resuscitation in a porcine model of prolonged hemorrhagic shock.
Topics: Adenosine; Animals; Cardioplegic Solutions; Disease Models, Animal; Emergency Medical Services; Lidocaine; Magnesium; Male; Military Medicine; Resuscitation; Shock, Hemorrhagic; Swine; Wounds and Injuries | 2019 |
Effect of Lidocaine Injection of Ganglionated Plexi in a Canine Model and Patients With Persistent and Long-Standing Persistent Atrial Fibrillation.
Topics: Action Potentials; Aged; Aged, 80 and over; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Function, Left; Disease Models, Animal; Dogs; Electrophysiologic Techniques, Cardiac; Female; Ganglia, Autonomic; Heart Atria; Heart Rate; Humans; Injections; Lidocaine; Male; Middle Aged; Time Factors; Treatment Outcome | 2019 |
Effects of Intradiscal Injection of Local Anesthetics on Intervertebral Disc Degeneration in Rabbit Degenerated Intervertebral Disc.
Topics: Anesthetics, Local; Animals; Bupivacaine; Disease Models, Animal; Intervertebral Disc; Intervertebral Disc Degeneration; Lidocaine; Nucleus Pulposus; Organ Culture Techniques; Rabbits | 2019 |
Adenosine, lidocaine, and Mg2+ fluid therapy leads to 72-hour survival after hemorrhagic shock: A model for studying differential gene expression and extending biological time.
Topics: Adenosine; Animals; Disease Models, Animal; Fluid Therapy; Gene Expression; Gene Expression Profiling; Lidocaine; Magnesium; Male; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Shock, Hemorrhagic; Time Factors | 2019 |
The cerebellum as a novel tinnitus generator.
Topics: Animals; Auditory Perception; Auditory Threshold; Cerebellum; Disease Models, Animal; Hearing Loss, Noise-Induced; Hyperacusis; Lidocaine; Magnetic Resonance Imaging; Male; Psychoacoustics; Rats; Rats, Long-Evans; Tinnitus | 2013 |
Reorganization of circuits underlying cerebellar modulation of prefrontal cortical dopamine in mouse models of autism spectrum disorder.
Topics: Animals; Cerebellum; Child Development Disorders, Pervasive; Disease Models, Animal; Dopamine; Infusions, Intraventricular; Kynurenic Acid; Lidocaine; Male; Mice; Mice, 129 Strain; Mice, Inbred CBA; Mice, Knockout; Mice, Neurologic Mutants; Nerve Net; Neuronal Plasticity; Prefrontal Cortex | 2013 |
The balance of striatal feedback transmission is disrupted in a model of parkinsonism.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adrenergic Agents; Anesthetics, Local; Animals; Animals, Newborn; Bicuculline; Biophysics; Calcium; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Antagonists; Feedback, Physiological; GABA Antagonists; gamma-Aminobutyric Acid; Green Fluorescent Proteins; In Vitro Techniques; Lidocaine; Lysine; Male; Mice; Mice, Transgenic; Monte Carlo Method; Neostriatum; Neural Inhibition; Neural Pathways; Neurons; Oxidopamine; Parkinsonian Disorders; Patch-Clamp Techniques; Pyridazines; Rats; Rats, Wistar; Reaction Time; Receptors, Dopamine D1; Receptors, Dopamine D2; Synaptic Transmission; Time Factors; Valine | 2013 |
Pain‑relieving effect of a compound isolated from white peony root oral liquid on acute radiation‑induced esophagitis.
Topics: Administration, Oral; Anesthetics, Local; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Body Weight; Dexamethasone; Disease Models, Animal; Esophagitis; Gentamicins; Immunohistochemistry; Lidocaine; Male; Paeonia; Pain Management; Plant Extracts; Plant Roots; Radiation Injuries; Rats; Rats, Wistar; Substance P; X-Rays | 2013 |
Descending facilitation maintains long-term spontaneous neuropathic pain.
Topics: Afferent Pathways; Anesthetics, Local; Animals; Benzodiazepines; Conditioning, Operant; Disease Models, Animal; Hormone Antagonists; Hyperalgesia; Lidocaine; Male; Medulla Oblongata; Neuralgia; Oncogene Proteins v-fos; Ondansetron; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Spinal Nerves; Time Factors | 2013 |
Administration of amiodarone during resuscitation is associated with higher tumor necrosis factor-α levels in the early postarrest period in the swine model of ischemic ventricular fibrillation.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Coronary Vessels; Disease Models, Animal; Heart Arrest; Hemodynamics; Inflammation; Lidocaine; Male; Myocardial Ischemia; Random Amplified Polymorphic DNA Technique; Swine; Tumor Necrosis Factor-alpha; Ventricular Fibrillation | 2013 |
Prophylactic amiodarone and lidocaine improve survival in an ovine model of large size myocardial infarction.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Disease Models, Animal; Hemodynamics; Lidocaine; Mortality; Myocardial Infarction; Severity of Illness Index; Sheep, Domestic; Tachycardia, Ventricular; Ventricular Fibrillation | 2013 |
The effects of adenocaine (adenosine and lidocaine) on early post-resuscitation cardiac and neurological dysfunction in a porcine model of cardiac arrest.
Topics: Adenosine; Animals; Brain Death; Cardiopulmonary Resuscitation; Cardiovascular Agents; Coronary Angiography; Disease Models, Animal; Drug Combinations; Heart Arrest; Hemodynamics; Lidocaine; Oxygen; Random Allocation; Reperfusion Injury; Survival Rate; Swine | 2013 |
Intra-articular anaesthesia mitigates established pain in experimental osteoarthritis: a preliminary study of gait impulse redistribution as a biomarker of analgesia pharmacodynamics.
Topics: Anesthetics, Local; Animals; Anterior Cruciate Ligament Injuries; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Arthritis, Experimental; Biomarkers; Disease Models, Animal; Dogs; Female; Femoral Fractures; Gait; Injections, Intra-Articular; Injections, Intradermal; Lidocaine; Male; Meloxicam; Osteoarthritis, Knee; Pilot Projects; Thiazines; Thiazoles; Weight-Bearing | 2013 |
Exploration of supraspinal mechanisms in effects of spinal cord stimulation: role of the locus coeruleus.
Topics: Action Potentials; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Anesthetics, Local; Animals; Disease Models, Animal; Electric Stimulation; Hyperalgesia; Imidazoles; Lidocaine; Locus Coeruleus; Male; Neural Pathways; Neurons; Pain Threshold; Physical Stimulation; Prazosin; Rats; Rats, Wistar; Sciatica; Spinal Cord | 2013 |
Lidocaine protects against renal and hepatic dysfunction in septic rats via downregulation of Toll‑like receptor 4.
Topics: Animals; Disease Models, Animal; Down-Regulation; Interleukin-6; Kidney; Lidocaine; Lipopolysaccharides; Liver; Male; NF-kappa B; Protective Agents; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sepsis; Toll-Like Receptor 4 | 2014 |
Nociceptor-selective peripheral nerve block induces delayed mechanical hypersensitivity and neurotoxicity in rats.
Topics: Anesthetics, Combined; Anesthetics, Local; Animals; Behavior, Animal; Capsaicin; Disease Models, Animal; Hyperalgesia; Hypersensitivity, Delayed; Lidocaine; Male; Nerve Block; Nerve Fibers; Neural Conduction; Neurotoxicity Syndromes; Nociceptors; Pain, Postoperative; Physical Stimulation; Rats; Rats, Sprague-Dawley; Sensory System Agents; TRPV Cation Channels | 2014 |
Recovery of motor neuron excitability after facial nerve impairment in rats.
Topics: Anesthetics, Local; Animals; Disease Models, Animal; Electric Stimulation; Electromyography; Evoked Potentials, Motor; Face; Facial Nerve Injuries; Lidocaine; Motor Neurons; Rats; Rats, Wistar; Recovery of Function; Time Factors | 2014 |
Small-volume 7.5% NaCl adenosine, lidocaine, and Mg2+ has multiple benefits during hypotensive and blood resuscitation in the pig following severe blood loss: rat to pig translation.
Topics: Adenosine; Animals; Blood Volume; Disease Models, Animal; Drug Therapy, Combination; Female; Fluid Therapy; Hemoglobin A; Hypotension; Infusions, Intravenous; Lidocaine; Magnesium; Oxygen Consumption; Rats; Rehydration Solutions; Shock, Hemorrhagic; Sodium Chloride; Stroke Volume; Sus scrofa; Vasodilator Agents | 2014 |
Effects of potassium/lidocaine-induced cardiac standstill during cardiopulmonary resuscitation in a pig model of prolonged ventricular fibrillation.
Topics: Animals; Biomarkers; Cardioplegic Solutions; Cardiopulmonary Resuscitation; Disease Models, Animal; Drug Combinations; Heart Arrest; Lidocaine; Male; Potassium Chloride; Random Allocation; Single-Blind Method; Sus scrofa; Troponin I; Ventricular Fibrillation; Ventricular Function, Left | 2014 |
Critical role of inflammatory cytokines in impairing biochemical processes for learning and memory after surgery in rats.
Topics: Animals; Carotid Arteries; Cytokines; Disease Models, Animal; Gene Expression Regulation; Hippocampus; In Vitro Techniques; Isoflurane; Learning Disabilities; Lidocaine; Male; Maze Learning; Memory Disorders; Postoperative Complications; Potassium Channel Blockers; Protein Transport; Rats; Rats, Inbred F344; Receptors, AMPA; Tetraethylammonium | 2014 |
Synergistic effect of lidocaine with pingyangmycin for treatment of venous malformation using a mouse spleen model.
Topics: Anesthetics, Local; Animals; Apoptosis; Bleomycin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Endothelial Cells; Female; Lidocaine; Mice; Microscopy, Electron, Transmission; Sclerosing Solutions; Splenic Vein; Time Factors | 2014 |
Adenosine, lidocaine and Mg2+ (ALM) induces a reversible hypotensive state, reduces lung edema and prevents coagulopathy in the rat model of polymicrobial sepsis.
Topics: Adenosine; Animals; Blood Coagulation Disorders; Disease Models, Animal; Drug Therapy, Combination; Edema; Hypotension; Infusions, Intravenous; Lidocaine; Lung Diseases; Magnesium; Male; Partial Thromboplastin Time; Prothrombin Time; Rats; Rats, Sprague-Dawley; Sepsis | 2014 |
Effects of Static Magnetic Fields on the Visual Cortex: reversible Visual Deficits and Reduction of Neuronal Activity.
Topics: Action Potentials; Analysis of Variance; Anesthetics, Local; Animals; Cats; Disease Models, Animal; Female; Lidocaine; Macaca mulatta; Male; Neurons; Paralysis; Reaction Time; Time Factors; Transcranial Magnetic Stimulation; Vision Disorders; Visual Cortex; Visual Perception; Wakefulness | 2016 |
Genetic background modulates impaired excitability of inhibitory neurons in a mouse model of Dravet syndrome.
Topics: Action Potentials; Animals; Animals, Newborn; Biophysical Phenomena; Conditioning, Psychological; Disease Models, Animal; Epilepsies, Myoclonic; Excitatory Postsynaptic Potentials; Fear; Hippocampus; Hyperthermia, Induced; In Vitro Techniques; Lidocaine; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; NAV1.1 Voltage-Gated Sodium Channel; Neural Inhibition; Sodium Channel Blockers | 2015 |
Haloperidol treatment at pre-exposure phase reduces the disturbance of latent inhibition in rats with neonatal ventral hippocampus lesions.
Topics: Animals; Animals, Newborn; Antipsychotic Agents; Behavior, Animal; Conditioning, Psychological; Disease Models, Animal; Haloperidol; Hippocampus; Lidocaine; Motor Activity; Rats; Rats, Sprague-Dawley; Schizophrenia; Schizotypal Personality Disorder; Taste | 2014 |
Genesis of anxiety, depression, and ongoing abdominal discomfort in ulcerative colitis-like colon inflammation.
Topics: Abdominal Pain; Action Potentials; Anesthetics, Local; Animals; Anxiety; Behavior, Animal; Colitis, Ulcerative; Colon; Conditioning, Psychological; Depression; Dextran Sulfate; Disease Models, Animal; Diterpenes; Ganglia, Spinal; Kv1.1 Potassium Channel; Kv1.4 Potassium Channel; Lidocaine; Rats; RNA, Messenger; Time Factors; TRPV Cation Channels | 2015 |
Nucleus incertus inactivation impairs spatial learning and memory in rats.
Topics: Anesthetics, Local; Animals; Avoidance Learning; Disease Models, Animal; Gene Expression Regulation; Hippocampus; Learning Disabilities; Lidocaine; Male; Maze Learning; Memory; Mental Recall; Motor Activity; Proto-Oncogene Proteins c-fos; Raphe Nuclei; Rats; Rats, Wistar; Reaction Time; Spatial Learning; Time Factors | 2015 |
Adenosine, lidocaine and Mg2+ improves cardiac and pulmonary function, induces reversible hypotension and exerts anti-inflammatory effects in an endotoxemic porcine model.
Topics: Adenosine; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Drug Therapy, Combination; Endotoxemia; Female; Heart; Hypotension; Inflammation Mediators; Lidocaine; Lung; Magnesium; Random Allocation; Respiratory Function Tests; Swine | 2014 |
The effects of epidural anesthesia on growth of Escherichia coli at pseudosurgical site: the roles of the lipocalin-2 pathway.
Topics: Anesthesia, Epidural; Anesthetics, Local; Animals; Cytokines; Disease Models, Animal; DNA, Bacterial; Escherichia coli; Escherichia coli Infections; Host-Pathogen Interactions; Inflammation Mediators; Lidocaine; Lipocalin-2; Lipocalins; Male; Rats, Wistar; RNA, Messenger; Signal Transduction; Surgical Wound Infection; Time Factors; Up-Regulation | 2015 |
Correction of acute traumatic coagulopathy with small-volume 7.5% NaCl adenosine, lidocaine, and Mg2+ occurs within 5 minutes: a ROTEM analysis.
Topics: Adenosine; Animals; Blood Coagulation Disorders; Disease Models, Animal; Hemodynamics; Lidocaine; Magnesium; Male; Partial Thromboplastin Time; Prothrombin Time; Random Allocation; Rats; Rats, Sprague-Dawley; Resuscitation; Shock, Hemorrhagic; Sodium Chloride; Thrombelastography; Time Factors | 2015 |
CaMKII Phosphorylation in Primary Somatosensory Cortical Neurons is Involved in the Inhibition of Remifentanil-induced Hyperalgesia by Lidocaine in Male Sprague-Dawley Rats.
Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Disease Models, Animal; Hyperalgesia; Lidocaine; Male; Neurons; Phosphorylation; Piperidines; Rats; Rats, Sprague-Dawley; Remifentanil; Somatosensory Cortex | 2016 |
Effect of a pharmacologically induced decrease in core temperature in rats resuscitated from cardiac arrest.
Topics: Anesthetics, Local; Animals; Body Temperature; Cardiopulmonary Resuscitation; Disease Models, Animal; Drug Combinations; Ethanol; Female; Heart Arrest; Hypothermia, Induced; Lidocaine; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents; Vasopressins | 2015 |
Behavioral and neurochemical analysis of ongoing bone cancer pain in rats.
Topics: Adenocarcinoma; Analgesics, Opioid; Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Bone Neoplasms; Cell Line, Tumor; Diclofenac; Disease Models, Animal; Female; Gyrus Cinguli; Lidocaine; Morphine; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Pain; Rats; Rats, Inbred F344 | 2015 |
Topical Tetrodotoxin Attenuates Photophobia Induced by Corneal Injury in the Rat.
Topics: Administration, Topical; Analysis of Variance; Anesthetics, Local; Animals; Corneal Injuries; Disease Models, Animal; Dose-Response Relationship, Drug; Lidocaine; Male; Photic Stimulation; Photophobia; Rats; Rats, Sprague-Dawley; Tetrodotoxin; Time Factors | 2015 |
Silencing Nociceptor Neurons Reduces Allergic Airway Inflammation.
Topics: Airway Remodeling; Anesthetics, Local; Animals; Animals, Newborn; Capsaicin; Cytokines; Disease Models, Animal; Freund's Adjuvant; Green Fluorescent Proteins; Interleukin-5; Lidocaine; Mice; Nociceptors; Ovalbumin; Respiratory Hypersensitivity; Time Factors; Vasoactive Intestinal Peptide | 2015 |
Comparative evaluation of in vitro and in vivo high glucose-induced alterations in voltage-gated tetrodotoxin-resistant sodium channel: Effects attenuated by sodium channel blockers.
Topics: Animals; Antibiotics, Antineoplastic; Cells, Cultured; Diabetes Mellitus, Experimental; Disease Models, Animal; Drug Interactions; Ganglia, Spinal; Glucose; Lidocaine; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Streptozocin; Sweetening Agents; Tetrodotoxin; Voltage-Gated Sodium Channels | 2015 |
Sciatic Nerve Intrafascicular Lidocaine Injection-induced Peripheral Neuropathic Pain: Alleviation by Systemic Minocycline Administration.
Topics: Activating Transcription Factor 3; Analysis of Variance; Anesthetics, Local; Animals; Anti-Bacterial Agents; CD11b Antigen; Disease Models, Animal; Ganglia, Spinal; Glial Fibrillary Acidic Protein; Lidocaine; Male; Minocycline; Myelin Basic Protein; Neuralgia; Neuroglia; Pain Measurement; Rats; Sciatic Nerve; Sodium Channels | 2016 |
Galanin-Mediated Behavioural Hyperalgesia from the Dorsomedial Nucleus of the Hypothalamus Involves Two Independent Descending Pronociceptive Pathways.
Topics: Animals; Arthritis; Behavior, Animal; Disease Models, Animal; Electrophysiology; Galanin; Glutamic Acid; Hyperalgesia; Hypothalamus; Lidocaine; Male; Mediodorsal Thalamic Nucleus; Neurons; Nociception; Ondansetron; Pain; Pressure; Protein Precursors; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT3; Serotonin; Spinal Cord | 2015 |
JM25-1, a Lidocaine Analog Combining Airway Relaxant and Antiinflammatory Properties: Implications for New Bronchospasm Therapy.
Topics: Anesthetics, Local; Animals; Anti-Inflammatory Agents; Bronchial Spasm; Disease Models, Animal; Inflammation; Lidocaine; Mice; Rats; Rats, Wistar; Trachea | 2016 |
Central Sensitization and Neuropathic Features of Ongoing Pain in a Rat Model of Advanced Osteoarthritis.
Topics: Analgesics; Animals; Arthralgia; Central Nervous System Sensitization; Disease Models, Animal; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Hindlimb; Lidocaine; Male; Medulla Oblongata; Neuralgia; Osteoarthritis, Knee; Proto-Oncogene Proteins c-fos; Rats, Sprague-Dawley; Spinal Cord | 2016 |
Distinct TRPV1- and TRPA1-based mechanisms underlying enhancement of oral ulcerative mucositis-induced pain by 5-fluorouracil.
Topics: Acetanilides; Anesthetics, Local; Animals; Anti-Bacterial Agents; Antimetabolites; Carcinosarcoma; Cyclooxygenase 2; Cytokines; Disease Models, Animal; Eating; Fluorouracil; Hyperalgesia; Leukocytes; Lidocaine; Male; Microbial Viability; Pain; Pain Management; Polymyxin B; Purines; Rats; Rats, Wistar; Stomatitis; Trigeminal Ganglion; TRPV Cation Channels | 2016 |
The smell of "anxiety": Behavioral modulation by experimental anosmia in zebrafish.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Antidepressive Agents, Second-Generation; Anxiety; Disease Models, Animal; Female; Fluoxetine; Hydrocortisone; Lidocaine; Locomotion; Male; Odorants; Olfaction Disorders; Statistics, Nonparametric; Zebrafish | 2016 |
The traditional Japanese medicine hangeshashinto alleviates oral ulcer-induced pain in a rat model.
Topics: Acetic Acid; Administration, Topical; Analgesics; Animals; Disease Models, Animal; Drugs, Chinese Herbal; Hypersensitivity; Indomethacin; Japan; Lidocaine; Male; Mouth Mucosa; Mouthwashes; Oral Ulcer; Pain; Random Allocation; Rats; Rats, Wistar; Stomatitis | 2016 |
The Potential Effect of Epidural Anesthesia on Mesenteric Injury after Supraceliac Aortic Clamping in a Rabbit Model.
Topics: Anesthesia, Epidural; Anesthetics, Local; Animals; Aorta, Abdominal; Biomarkers; Constriction; Disease Models, Animal; Interleukin-6; Lidocaine; Male; Malondialdehyde; Mesenteric Arteries; Mesenteric Ischemia; Rabbits; Regional Blood Flow; Reperfusion Injury; Serum Albumin; Serum Albumin, Human; Splanchnic Circulation; Superoxide Dismutase; Time Factors; Vascular Surgical Procedures | 2016 |
Hypovolemic hemorrhage induces Fos expression in the rat hypothalamus: Evidence for involvement of the lateral hypothalamus in the decompensatory phase of hemorrhage.
Topics: Animals; Bradycardia; Cobalt; Disease Models, Animal; Hemorrhage; Hemostatics; Hypothalamus; Hypovolemia; Lidocaine; Male; Neurons; Proto-Oncogene Proteins c-fos; Rats, Sprague-Dawley | 2016 |
Functional characterization of a mouse model for central post-stroke pain.
Topics: Animals; Collagenases; Disease Models, Animal; Hyperalgesia; Kainic Acid; Lidocaine; Mice, Inbred C57BL; Microinjections; Nerve Fibers, Unmyelinated; Pain; Sensation; Spinal Cord; Stroke; Thalamus; TRPV Cation Channels; Ventral Thalamic Nuclei | 2016 |
Lidocaine Enhances Contractile Function of Ischemic Myocardial Regions in Mouse Model of Sustained Myocardial Ischemia.
Topics: Animals; Diastole; Disease Models, Animal; Electrocardiography; Lidocaine; Mice; Mice, Inbred BALB C; Myocardial Contraction; Myocardial Ischemia; Systole; Ventricular Dysfunction, Left | 2016 |
Localized Sympathectomy Reduces Mechanical Hypersensitivity by Restoring Normal Immune Homeostasis in Rat Models of Inflammatory Pain.
Topics: Anesthetics, Local; Animals; Cytokines; Disease Models, Animal; Female; Ganglia, Spinal; Homeostasis; Hyperalgesia; Inflammation; Lidocaine; Male; Membrane Potentials; Pain; Pain Measurement; Pain Threshold; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Sympathectomy; Tyrosine 3-Monooxygenase | 2016 |
ATP-sensitive muscle afferents activate spinal trigeminal neurons with meningeal afferent input in rat - pathophysiological implications for tension-type headache.
Topics: Adenosine Triphosphate; Animals; Disease Models, Animal; Dura Mater; Lidocaine; Male; Muscle, Skeletal; Neurons; Neurons, Afferent; Rats; Rats, Wistar; Tension-Type Headache | 2016 |
Small-Volume Adenosine, Lidocaine, and Mg2+ 4-Hour Infusion Leads to 88% Survival after 6 Days of Experimental Sepsis in the Rat without Antibiotics.
Topics: Acidosis; Adenosine; Animals; Anti-Bacterial Agents; C-Reactive Protein; Cytokines; Disease Models, Animal; Drug Therapy, Combination; Edema; Hyperkalemia; Infusions, Intravenous; Interleukin-1beta; Interleukin-6; Lidocaine; Magnesium Sulfate; Male; Rats; Sepsis | 2016 |
Effect of dexmedetomidine priming on convulsion reaction induced by lidocaine.
Topics: Administration, Topical; Adrenergic alpha-2 Receptor Agonists; Anesthetics, Local; Animals; Dexmedetomidine; Disease Models, Animal; Dose-Response Relationship, Drug; Lidocaine; Male; Rabbits; Seizures | 2016 |
CaMKIIα underlies spontaneous and evoked pain behaviors in Berkeley sickle cell transgenic mice.
Topics: Anemia, Sickle Cell; Anesthetics, Local; Animals; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Conditioning, Operant; Disease Models, Animal; Enzyme Inhibitors; Formaldehyde; Ganglia, Spinal; Gene Expression Regulation; Hemoglobins; Hyperalgesia; Inflammation; Lidocaine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Pain; Pain Threshold; Physical Stimulation; Spinal Cord; Sulfonamides | 2016 |
Lidocaine Administration Controls MicroRNAs Alterations Observed After Lung Ischemia-Reperfusion Injury.
Topics: Animals; Apoptosis Regulatory Proteins; Disease Models, Animal; Gene Expression Regulation; Inflammation Mediators; Lidocaine; Lung; Lung Injury; Lung Transplantation; Male; MicroRNAs; Reperfusion Injury; Sus scrofa; Time Factors; Transplantation, Autologous | 2016 |
Pain Input Impairs Recovery after Spinal Cord Injury: Treatment with Lidocaine.
Topics: Anesthetics, Local; Animals; Disease Models, Animal; Lidocaine; Male; Pain; Rats; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord Injuries | 2017 |
New approach to molsidomine active metabolites coming from the results of 2 models of experimental cardiology.
Topics: Animals; Anti-Asthmatic Agents; Arrhythmias, Cardiac; Creatine Kinase; Disease Models, Animal; Hemodynamics; Isolated Heart Preparation; Lidocaine; Male; Molsidomine; Nitrosamines; Rats; Reperfusion Injury | 2017 |
Bupivacaine increases the rate of motoneuron death following peripheral nerve injury.
Topics: Animals; Axotomy; Bupivacaine; Cell Death; Disease Models, Animal; Lidocaine; Male; Mice; Mice, Inbred C57BL; Motor Neurons; Peripheral Nerve Injuries | 2017 |
pH-sensitive niosomes: Effects on cytotoxicity and on inflammation and pain in murine models.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; BALB 3T3 Cells; Cells, Cultured; Disease Models, Animal; Fibroblasts; Humans; Hydrogen-Ion Concentration; Ibuprofen; Inflammation; Lidocaine; Liposomes; Mice; Pain; Pain Measurement; Surface-Active Agents | 2017 |
Lidocaine Induces Apoptosis and Suppresses Tumor Growth in Human Hepatocellular Carcinoma Cells In Vitro and in a Xenograft Model In Vivo.
Topics: Anesthetics, Local; Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Hep G2 Cells; Heterografts; Humans; In Vitro Techniques; Lidocaine; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Xenograft Model Antitumor Assays | 2017 |
Comparative antiallodynic activity of morphine, pregabalin and lidocaine in a rat model of neuropathic pain produced by one oxaliplatin injection.
Topics: Analgesics; Analysis of Variance; Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Lidocaine; Male; Morphine; Neuralgia; Organoplatinum Compounds; Oxaliplatin; Pain Measurement; Pain Threshold; Pregabalin; Rats; Rats, Sprague-Dawley; Reaction Time | 2008 |
Mechanisms of atrial fibrillation termination by rapidly unbinding Na+ channel blockers: insights from mathematical models and experimental correlates.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Body Surface Potential Mapping; Computer Simulation; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Heart Conduction System; Kinetics; Lidocaine; Models, Cardiovascular; Potassium; Sodium; Sodium Channel Blockers; Sodium Channels; Vagus Nerve | 2008 |
Electroanatomic mapping of the left ventricle in a porcine model of chronic myocardial infarction with magnetic resonance-based catheter tracking.
Topics: Animals; Catheter Ablation; Catheterization; Disease Models, Animal; Electrophysiologic Techniques, Cardiac; Heart Ventricles; Lidocaine; Magnetic Resonance Imaging; Myocardial Infarction; Swine; Tachycardia, Ventricular | 2008 |
Governing role of primary afferent drive in increased excitation of spinal nociceptive neurons in a model of sciatic neuropathy.
Topics: Anesthetics, Local; Animals; Disease Models, Animal; Lidocaine; Male; Membrane Potentials; Nerve Block; Nociceptors; Physical Stimulation; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy; Skin; Spinal Cord | 2008 |
The effect of intravenous lidocaine on brain activation during non-noxious and acute noxious stimulation of the forepaw: a functional magnetic resonance imaging study in the rat.
Topics: Anesthetics, Local; Animals; Brain; Brain Mapping; Disease Models, Animal; Electric Stimulation; Female; Forelimb; Image Interpretation, Computer-Assisted; Infusions, Intravenous; Lidocaine; Limbic System; Magnetic Resonance Imaging; Pain; Rats; Rats, Sprague-Dawley; Somatosensory Cortex; Thalamus | 2009 |
Spinal NK-1 receptor-expressing neurons and descending pathways support fentanyl-induced pain hypersensitivity in a rat model of postoperative pain.
Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Disease Models, Animal; Dynorphins; Fentanyl; Immunohistochemistry; Lidocaine; Male; Medulla Oblongata; Neural Pathways; Neurons; Pain Threshold; Pain, Postoperative; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Spinal Cord | 2009 |
Lidocaine prevents referred hyperalgesia associated with cystitis.
Topics: Administration, Intravesical; Anesthetics, Local; Animals; Cystitis; Disease Models, Animal; Female; Ganglia, Spinal; Hyperalgesia; Injections, Spinal; Lidocaine; Nerve Growth Factor; Pain Measurement; Pain Threshold; Rats; Rats, Wistar; Time Factors; Urinary Bladder | 2009 |
Early termination of spiral wave reentry by combined blockade of Na+ and L-type Ca2+ currents in a perfused two-dimensional epicardial layer of rabbit ventricular myocardium.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Disease Models, Animal; Electrophysiologic Techniques, Cardiac; Heart Rate; Heart Ventricles; Lidocaine; Pericardium; Rabbits; Sodium Channel Blockers; Sodium Channels; Tachycardia, Sinoatrial Nodal Reentry; Treatment Outcome; Verapamil | 2009 |
Mapping ventricular fibrillation: a simplified experimental model leads to a complicated result.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Disease Models, Animal; Electrophysiologic Techniques, Cardiac; Heart Rate; Heart Ventricles; Lidocaine; Pericardium; Rabbits; Sodium Channel Blockers; Sodium Channels; Tachycardia, Ventricular; Treatment Outcome; Verapamil | 2009 |
fMRI investigation of the effect of local and systemic lidocaine on noxious electrical stimulation-induced activation in spinal cord.
Topics: Anesthetics, Local; Animals; Blood Pressure; Disease Models, Animal; Drug Administration Routes; Electric Stimulation; Image Processing, Computer-Assisted; Lidocaine; Magnetic Resonance Imaging; Oxygen; Pain; Rats; Rats, Sprague-Dawley; Reaction Time; Spinal Cord; Time Factors | 2009 |
Persistent deep mechanical hyperalgesia induced by repeated cold stress in rats.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Chronic Disease; Cold Temperature; Disease Models, Animal; Hyperalgesia; Lidocaine; Male; Muscle, Skeletal; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Stress, Physiological | 2010 |
Oxidative stress of intracameral lidocaine and levobupivacaine on ocular tissues.
Topics: Anesthetics, Local; Animals; Anterior Chamber; Bupivacaine; Cornea; Corneal Opacity; Disease Models, Animal; Lens, Crystalline; Levobupivacaine; Lidocaine; Malondialdehyde; Oxidative Stress; Rabbits; Sulfhydryl Compounds | 2010 |
Effects of pre-emptive drug treatment on astrocyte activation in the cuneate nucleus following rat median nerve injury.
Topics: Adrenergic alpha-Agonists; Animals; Astrocytes; Citrates; Clonidine; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glial Fibrillary Acidic Protein; Hyperalgesia; Lidocaine; Male; Median Neuropathy; Medulla Oblongata; Pain Threshold; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Tetrodotoxin; Time Factors; Up-Regulation | 2010 |
Cellular basis for atrial fibrillation in an experimental model of short QT1: implications for a pharmacological approach to therapy.
Topics: Action Potentials; Analysis of Variance; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Chlorobenzenes; Disease Models, Animal; Dogs; Electrocardiography; Isoproterenol; Lidocaine; ortho-Aminobenzoates; Quinidine | 2010 |
Urodynamic effects of the bladder C-fiber afferent activity modulation in chronic model of overactive bladder in rats.
Topics: Administration, Intravesical; Afferent Pathways; Anesthetics, Local; Animals; Capsaicin; Cystitis; Disease Models, Animal; Female; Lidocaine; Nerve Fibers, Unmyelinated; Random Allocation; Rats; Rats, Wistar; Sensory System Agents; Urinary Bladder; Urinary Bladder, Overactive; Urination; Urodynamics | 2009 |
Preemptive analgesic effect of lidocaine in a chronic neuropathic pain model.
Topics: Anesthetics, Local; Animals; Chronic Disease; Disease Models, Animal; Lidocaine; Pain, Postoperative; Rats; Rats, Wistar; Sciatic Nerve; Sciatica; Time Factors | 2009 |
How the heart can fibrillate: when diversity is a disadvantage.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Chlorobenzenes; Disease Models, Animal; Dogs; Humans; Lidocaine; ortho-Aminobenzoates; Quinidine | 2010 |
Delta oscillation and short-term plasticity in the rat medial prefrontal cortex: modelling NMDA hypofunction of schizophrenia.
Topics: Animals; Biphenyl Compounds; Delta Rhythm; Disease Models, Animal; Dizocilpine Maleate; Electric Stimulation; Electroencephalography; Excitatory Postsynaptic Potentials; Hippocampus; Lidocaine; Male; N-Methylaspartate; Neuronal Plasticity; Prefrontal Cortex; Quinazolines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Sulfonamides; Synaptic Transmission; Time Factors | 2011 |
[A study of the protective effects of lidocaine and nerve growth factor pretreatment on cerebral ischemia/reperfusion injury in gerbils].
Topics: Animals; Apoptosis; Brain Ischemia; Disease Models, Animal; Gerbillinae; Ischemic Preconditioning; Lidocaine; Nerve Growth Factor; Neurons; Reperfusion Injury | 2010 |
Clinically relevant doses of lidocaine and bupivacaine do not impair cutaneous wound healing in mice.
Topics: Aging; Anesthetics, Local; Animals; Bupivacaine; Collagen; Dermatologic Surgical Procedures; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Lidocaine; Mice; Mice, Inbred C57BL; Postmenopause; Skin; Wound Healing | 2010 |
Long-term effect of sciatic nerve block with slow-release lidocaine in a rat model of postoperative pain.
Topics: Animals; Delayed-Action Preparations; Disease Models, Animal; Drug Delivery Systems; Lidocaine; Male; Nerve Block; Pain, Postoperative; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Time Factors | 2010 |
Spinal cord injury immediately changes the state of the brain.
Topics: Afferent Pathways; Analysis of Variance; Animals; Biophysics; Disease Models, Animal; Electric Stimulation; Electroencephalography; Evoked Potentials, Somatosensory; Lidocaine; Lower Extremity; Male; Rats; Rats, Wistar; Sodium Channel Blockers; Somatosensory Cortex; Spinal Cord Injuries; Statistics as Topic; Tetrodotoxin | 2010 |
Thoracic epidural anesthesia attenuates endotoxin-induced impairment of gastrointestinal organ perfusion.
Topics: Anesthesia, Epidural; Anesthetics, Local; Animals; Catecholamines; Disease Models, Animal; Endotoxemia; Endotoxins; Gastrointestinal Tract; Lidocaine; Male; Microcirculation; Microspheres; Rats; Rats, Sprague-Dawley; Sodium Chloride; Thoracic Vertebrae | 2010 |
Differential effects of four xylidine derivatives in the model of ischemia- and re-perfusion-induced arrhythmias in rats in vivo.
Topics: Amides; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Carticaine; Disease Models, Animal; Dose-Response Relationship, Drug; Heart Rate; Lidocaine; Male; Mepivacaine; Myocardial Reperfusion Injury; Rats; Rats, Sprague-Dawley; Ropivacaine; Severity of Illness Index; Tachycardia; Time Factors; Ventricular Fibrillation | 2010 |
Do local anesthetics have antibacterial effect on Staphylococcus aureus under in vivo conditions? An experimental study.
Topics: Anesthetics, Local; Animals; Bupivacaine; Carticaine; Disease Models, Animal; Lidocaine; Male; Prilocaine; Rats; Rats, Sprague-Dawley; Staphylococcal Infections; Staphylococcus aureus; Surgical Wound Infection | 2010 |
Acute amiodarone promotes drift and early termination of spiral wave re-entry.
Topics: Action Potentials; Amiodarone; Animals; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Disease Models, Animal; Electrophysiologic Techniques, Cardiac; Heart Conduction System; Heart Ventricles; Kinetics; Lidocaine; Perfusion; Rabbits; Tachycardia, Ventricular | 2010 |
The influence of anaesthetics on the reverse-flow fasciocutaneous flaps.
Topics: Anesthesia, Epidural; Anesthetics, Local; Animals; Disease Models, Animal; Lidocaine; Rabbits; Skin Transplantation; Surgical Flaps | 2011 |
Prolonged suppression of postincisional pain by a slow-release formulation of lidocaine.
Topics: Anesthetics, Local; Animals; Behavior, Animal; Delayed-Action Preparations; Disease Models, Animal; Drug Implants; Follow-Up Studies; Lidocaine; Male; Pain, Postoperative; Rats; Rats, Sprague-Dawley; Sciatic Nerve | 2011 |
Changes in the blood flow and prevention of vasospasm of the femoral artery by topical application of lidocaine in rats.
Topics: Administration, Topical; Anesthetics, Local; Animals; Constriction, Pathologic; Disease Models, Animal; Drug Administration Schedule; Epinephrine; Femoral Artery; Free Tissue Flaps; Lidocaine; Male; Microcirculation; Microsurgery; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents | 2011 |
Inhibition of cardiac Ca2+ release channels (RyR2) determines efficacy of class I antiarrhythmic drugs in catecholaminergic polymorphic ventricular tachycardia.
Topics: Analysis of Variance; Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Calsequestrin; Defibrillators, Implantable; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Countershock; Electrocardiography; Flecainide; Humans; Ion Channel Gating; Lidocaine; Male; Mice; Mice, Knockout; Mutation, Missense; Myocytes, Cardiac; Procainamide; Propafenone; Ryanodine Receptor Calcium Release Channel; Sodium Channel Blockers; Tachycardia, Ventricular; Time Factors; Young Adult | 2011 |
Transcriptional repression of the M channel subunit Kv7.2 in chronic nerve injury.
Topics: Aminopyridines; Analgesics; Analysis of Variance; Anesthetics, Local; Animals; Chronic Disease; Disease Models, Animal; Ganglia, Spinal; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Glycoproteins; Hyperalgesia; Indoles; KCNQ2 Potassium Channel; Lectins; Lidocaine; Male; Membrane Potentials; Neurofilament Proteins; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Repressor Proteins; RNA, Messenger; Sciatic Neuropathy; TRPV Cation Channels; Versicans | 2011 |
Lidocaine suppresses the increased extracellular signal-regulated kinase/cyclic AMP response element-binding protein pathway and pro-inflammatory cytokines in a neuropathic pain model of rats.
Topics: Anesthetics, Local; Animals; Cyclic AMP Response Element-Binding Protein; Cytokines; Disease Models, Animal; Inflammation Mediators; Lidocaine; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neuralgia; Random Allocation; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2011 |
Effect of local and intravenous lidocaine on ongoing activity in injured afferent nerve fibers.
Topics: Action Potentials; Anesthetics, Local; Animals; Blood Pressure; Disease Models, Animal; Drug Administration Routes; Electric Stimulation; Lidocaine; Male; Nerve Fibers; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Pain Threshold; Peripheral Nervous System Diseases; Rats; Rats, Wistar; Reaction Time; Skin; Statistics, Nonparametric; Time Factors | 2011 |
Time-dependent changes in bladder function and plantar sensitivity in a rat model of fibromyalgia syndrome induced by hydrochloric acid injection into the gluteus.
Topics: Anesthetics, Local; Animals; Case-Control Studies; Chronic Pain; Disease Models, Animal; Female; Fibromyalgia; Hindlimb; Hydrochloric Acid; Lidocaine; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; Time Factors; Urinary Bladder; Urinary Bladder, Overactive; Urination | 2012 |
Comparison of actions of systemically and locally administrated local anaesthetics in diabetic rats with painful neuropathy.
Topics: Anesthetics, Local; Animals; Bupivacaine; Diabetes Mellitus, Experimental; Disease Models, Animal; Female; Hyperalgesia; Hyperglycemia; Injections, Intraperitoneal; Levobupivacaine; Lidocaine; Neuralgia; Rats; Rats, Wistar | 2013 |
Time course of acute neuroprotective effects of lidocaine evaluated by brain impedanciometry in the global ischemia model.
Topics: Animals; Brain; Brain Edema; Brain Ischemia; Disease Models, Animal; Electric Impedance; Lidocaine; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley | 2011 |
Effect of epidural anesthesia on anastomotic leakage in colonic surgery: experimental study.
Topics: Anastomosis, Surgical; Anastomotic Leak; Anesthesia, Epidural; Anesthetics, Local; Animals; Colonic Diseases; Disease Models, Animal; Laparoscopy; Lidocaine; Male; Postoperative Complications; Rabbits; Wound Healing | 2012 |
Afferent drive elicits ongoing pain in a model of advanced osteoarthritis.
Topics: Afferent Pathways; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Injections, Intra-Articular; Lidocaine; Male; Neurons, Afferent; Osteoarthritis; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Severity of Illness Index; TRPV Cation Channels; Weight-Bearing | 2012 |
Analgesic effects of lidocaine, morphine and diclofenac on movement-induced nociception, as assessed by the Knee-Bend and CatWalk tests in a rat model of osteoarthritis.
Topics: Administration, Oral; Analgesics; Animals; Arthralgia; Diclofenac; Disease Models, Animal; Injections, Intra-Articular; Injections, Subcutaneous; Lidocaine; Male; Morphine; Movement; Nociception; Osteoarthritis; Pain Measurement; Rats; Rats, Wistar | 2012 |
Hyperalgesia by low doses of the local anesthetic lidocaine involves cannabinoid signaling: an fMRI study in mice.
Topics: Anesthetics, Local; Animals; Cannabinoids; Disease Models, Animal; Female; Hyperalgesia; Lidocaine; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nociceptors; Pain; Pain Measurement; Receptor, Cannabinoid, CB1 | 2012 |
A larval zebrafish model of bipolar disorder as a screening platform for neuro-therapeutics.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Antipsychotic Agents; Bipolar Disorder; Dark Adaptation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; GABA Antagonists; Haloperidol; Larva; Lidocaine; Pentylenetetrazole; Seizures; Video Recording; Zebrafish | 2012 |
Differential effects of peripheral versus central coadministration of QX-314 and capsaicin on neuropathic pain in rats.
Topics: Anesthetics, Local; Animals; Antipruritics; Capsaicin; Disease Models, Animal; Drug Administration Routes; Drug Therapy, Combination; Hyperalgesia; Lidocaine; Male; Neuralgia; Peripheral Nerves; Rats; Rats, Sprague-Dawley | 2012 |
Brainstem injection of lidocaine releases the descending pain-inhibitory mechanisms in a rat model of mononeuropathy.
Topics: Animals; Brain Stem; Cold Temperature; Disease Models, Animal; Female; Hot Temperature; Injections, Spinal; Lidocaine; Microinjections; Mononeuropathies; Pain Measurement; Rats; Rats, Sprague-Dawley | 2012 |
Reversal of acute coagulopathy during hypotensive resuscitation using small-volume 7.5% NaCl adenocaine and Mg2+ in the rat model of severe hemorrhagic shock.
Topics: Adenosine; Animals; Blood Coagulation Disorders; Disease Models, Animal; Drug Combinations; Hemodynamics; Lidocaine; Magnesium; Male; Partial Thromboplastin Time; Prothrombin Time; Rats; Resuscitation; Shock, Hemorrhagic; Sodium Chloride | 2012 |
Nebulized lidocaine prevents airway inflammation, peribronchial fibrosis, and mucus production in a murine model of asthma.
Topics: Anesthetics, Local; Animals; Asthma; Bronchi; Disease Models, Animal; Fibrosis; GATA3 Transcription Factor; Lidocaine; Lung; Male; Matrix Metalloproteinase 9; Mice; Mucus; Nebulizers and Vaporizers; T-Lymphocytes | 2012 |
Effect of local anesthetic on microorganisms in a murine model of surgical site infection.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Disease Models, Animal; Escherichia coli; Female; Incidence; Injections, Subcutaneous; Lidocaine; Mice; Mice, Inbred Strains; Microbial Viability; Preoperative Care; Random Allocation; Reference Values; Sensitivity and Specificity; Staphylococcus aureus; Surgical Wound Infection | 2012 |
Long-term effect of epidural injection with sustained-release lidocaine particles in a rat model of postoperative pain.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Delayed-Action Preparations; Disease Models, Animal; Dose-Response Relationship, Drug; Injections, Epidural; Lidocaine; Male; Pain Measurement; Pain, Postoperative; Rats; Rats, Sprague-Dawley; Time | 2012 |
Adenocaine and Mg(2+) reduce fluid requirement to maintain hypotensive resuscitation and improve cardiac and renal function in a porcine model of severe hemorrhagic shock*.
Topics: Adenosine; Animals; Disease Models, Animal; Drug Combinations; Female; Fluid Therapy; Heart; Hypotension; Kidney; Lidocaine; Magnesium; Resuscitation; Severity of Illness Index; Shock, Hemorrhagic; Swine | 2012 |
Clinically relevant animal models needed to advance state of the art fluid resuscitation*.
Topics: Adenosine; Animals; Disease Models, Animal; Drug Combinations; Female; Fluid Therapy; Heart; Hypotension; Kidney; Lidocaine; Magnesium; Resuscitation; Shock, Hemorrhagic | 2012 |
Phenotyping the function of TRPV1-expressing sensory neurons by targeted axonal silencing.
Topics: Action Potentials; Anesthetics, Local; Animals; Axons; Behavior, Animal; Capsaicin; Chronic Pain; Disease Models, Animal; Lidocaine; Male; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Sensory Receptor Cells; TRPV Cation Channels | 2013 |
A role for abdominal vagal afferents in lipopolysaccharide-induced hypotension.
Topics: Animals; Blood Pressure Determination; Capsaicin; Disease Models, Animal; Drug Interactions; Female; Hypotension; Injections, Intravenous; Leukocyte Count; Lidocaine; Lipopolysaccharides; Nerve Block; Neutrophils; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Reference Values; Sensitivity and Specificity; Shock, Septic; Vagus Nerve | 2002 |
The effect of local hematoma blocks on early fracture healing.
Topics: Analysis of Variance; Animals; Bupivacaine; Disease Models, Animal; Femoral Fractures; Fracture Fixation; Fracture Healing; Hematoma; Injections, Intralesional; Lidocaine; Male; Probability; Random Allocation; Rats; Rats, Long-Evans; Reference Values; Sensitivity and Specificity; Tensile Strength; Weight-Bearing | 2002 |
A comparison of the antinociceptive effects of voltage-activated Na+ channel blockers in two rat models of neuropathic pain.
Topics: Analgesics; Analysis of Variance; Anesthetics, Local; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Hindlimb; Lamotrigine; Lidocaine; Male; Mexiletine; Neuralgia; Pain Measurement; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Sodium Channels; Time Factors; Tocainide; Triazines | 2003 |
Myocardial protective effect of lidocaine during experimental off-pump coronary artery bypass grafting.
Topics: Animals; Coronary Artery Bypass; Disease Models, Animal; Female; Lidocaine; Male; Myocardial Reperfusion Injury; Random Allocation; Swine; Time Factors; Ventricular Function, Left | 2003 |
Electrical heterogeneity and arrhythmogenesis: importance of conduction velocity dispersion.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Vessels; Disease Models, Animal; Electrocardiography; Electrophysiology; Heart; Heart Conduction System; Infusion Pumps; Lidocaine; Refractory Period, Electrophysiological; Sotalol; Swine; Ventricular Fibrillation | 2003 |
Involvement of the anterior pretectal nucleus in the control of persistent pain: a behavioral and c-Fos expression study in the rat.
Topics: Anesthetics, Local; Animals; Bupivacaine; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Functional Laterality; Hyperalgesia; Immunohistochemistry; Lidocaine; Male; Mesencephalon; Microinjections; Pain; Pain Measurement; Pain Threshold; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Skin; Spinal Cord | 2003 |
Noradrenaline release in the median preoptic nucleus area caused by hemorrhage in the rat.
Topics: Anesthetics, Local; Animals; Blood; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Extracellular Space; Hemorrhage; Lidocaine; Male; Microdialysis; Norepinephrine; Preoptic Area; Rats; Rats, Wistar; Sodium Chloride | 2003 |
Effect of granulocyte colony-stimulating factor on bleomycin-induced acute lung injury and pulmonary fibrosis.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Cell Adhesion; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; Granulocyte Colony-Stimulating Factor; Instillation, Drug; Lidocaine; Lung Compliance; Male; Neutrophil Activation; Neutrophil Infiltration; Pulmonary Alveoli; Pulmonary Fibrosis; Random Allocation; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome | 2003 |
Tedisamil and lidocaine enhance each other's antiarrhythmic activity against ischaemia-induced arrhythmias in rats.
Topics: Animals; Anti-Asthmatic Agents; Arrhythmias, Cardiac; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Cyclopropanes; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Electrocardiography; Injections, Intravenous; Lidocaine; Myocardial Ischemia; Rats | 2003 |
Attenuation of neuropathic manifestations by local block of the activities of the ventrolateral orbito-frontal area in the rat.
Topics: Adrenergic Agents; Anesthetics, Local; Animals; Cold Temperature; Disease Models, Animal; Electricity; Excitatory Amino Acid Agonists; Female; Hindlimb; Hot Temperature; Hyperalgesia; Kainic Acid; Lidocaine; Mononeuropathies; Nerve Block; Oxidopamine; Pain; Pain Measurement; Pain Threshold; Physical Stimulation; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reference Values; Somatosensory Cortex | 2003 |
Free radical-induced damage in experimental peripheral nerve injection injury.
Topics: Analysis of Variance; Animals; Biopsy, Needle; Disease Models, Animal; Immunohistochemistry; Injury Severity Score; Lidocaine; Male; Peripheral Nerve Injuries; Phenol; Probability; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury; Risk Assessment; Sciatic Nerve; Sensitivity and Specificity; Thiobarbituric Acid Reactive Substances; Wounds and Injuries | 2003 |
Acute pancreatitis possible initial triggering mechanism and prophylaxis.
Topics: Acute Disease; Anesthetics, Local; Animals; Disease Models, Animal; Duodenum; Lidocaine; Male; Pancreas; Pancreatitis; Rats; Rats, Wistar; Reflex; Visceral Afferents | 2003 |
Mechanism of ST elevation and ventricular arrhythmias in an experimental Brugada syndrome model.
Topics: Animals; Disease Models, Animal; Dogs; Electrocardiography; Female; In Vitro Techniques; Lidocaine; Male; Pinacidil; Potassium Channels; Sodium Channel Blockers; Syndrome; Tachycardia, Ventricular | 2004 |
Surfactant lavage with lidocaine improves pulmonary function in piglets after HCl-induced acute lung injury.
Topics: Adjuvants, Immunologic; Animals; Bronchoalveolar Lavage; Disease Models, Animal; Drug Therapy, Combination; Female; Hydrochloric Acid; Lidocaine; Lung; Male; Pulmonary Surfactants; Reference Values; Respiratory Distress Syndrome; Respiratory Function Tests; Surface Tension; Swine | 2004 |
Key role of the dorsal root ganglion in neuropathic tactile hypersensibility.
Topics: Anesthetics, Local; Animals; Disease Models, Animal; Ganglia, Spinal; Hindlimb; Hyperesthesia; Lidocaine; Male; Neuralgia; Pain Threshold; Rats; Rats, Wistar; Rhizotomy; Synaptic Transmission | 2004 |
Lidocaine attenuates apoptosis in the ischemic penumbra and reduces infarct size after transient focal cerebral ischemia in rats.
Topics: Animals; Apoptosis; Caspase 3; Caspases; Cerebral Infarction; Cerebrovascular Circulation; Cytochromes c; Disease Models, Animal; DNA Fragmentation; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Lidocaine; Male; Nerve Degeneration; Rats; Rats, Wistar; Reaction Time; Recovery of Function; Treatment Outcome | 2004 |
Primary nerve repair by muscle autografts prepared with local anesthetic.
Topics: Anesthesia, Local; Animals; Disease Models, Animal; Female; Lidocaine; Male; Microscopy, Confocal; Muscle Fibers, Skeletal; Muscle, Skeletal; Nerve Regeneration; Rats; Rats, Wistar; Reference Values; Sciatic Nerve; Sensitivity and Specificity; Tissue Transplantation; Transplantation, Autologous | 2004 |
Pharmacological characterisation of the rat brachial plexus avulsion model of neuropathic pain.
Topics: Acetates; Amines; Analgesics; Analysis of Variance; Animals; Brachial Plexus; Brachial Plexus Neuropathies; Celecoxib; Clonidine; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Ketamine; Lidocaine; Male; Morphine; Neuralgia; Nociceptors; Pain Measurement; Pain Threshold; Pyrazoles; Radiculopathy; Rats; Rats, Wistar; Sulfonamides | 2004 |
Antinociception induced by stimulating the anterior pretectal nucleus in two models of pain in rats.
Topics: Analgesia; Anesthetics, Local; Animals; Brain; Disease Models, Animal; Efferent Pathways; Electric Stimulation; Hindlimb; Lidocaine; Male; Microinjections; Pain; Pain Threshold; Rats; Rats, Wistar; Spinal Cord; Tail; Time Factors | 2004 |
Beneficial effect of trimebutine and N-monodesmethyl trimebutine on trinitrobenzene sulfonic acid-induced colitis in rats.
Topics: Administration, Rectal; Anesthetics, Local; Animals; Bupivacaine; Colitis; Colon; Disease Models, Animal; Dose-Response Relationship, Drug; Gastrointestinal Agents; Injections, Subcutaneous; Lidocaine; Male; Organ Size; Rats; Rats, Sprague-Dawley; Trimebutine; Trinitrobenzenesulfonic Acid | 2004 |
Evaluation of the tail formalin test in mice as a new model to assess local analgesic effects.
Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Lidocaine; Male; Mice; Mice, Inbred ICR; Morphine; Pain; Pain Measurement; Tail | 2004 |
Mexiletine protects myocardium during acute ischemia by opening sarcolemmal K-ATP channel: studies in closed-chest acute ischemia model in rabbits.
Topics: Acute Disease; Animals; Anti-Arrhythmia Agents; ATP-Binding Cassette Transporters; Disease Models, Animal; Electrocardiography; Hemodynamics; KATP Channels; Lidocaine; Mexiletine; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rabbits; Sarcolemma; Sodium Channel Blockers; Stroke Volume; Ventricular Function, Left | 2004 |
Central neuropathic itch from spinal-cord cavernous hemangioma: a human case, a possible animal model, and hypotheses about pathogenesis.
Topics: Anesthetics, Local; Animals; Disease Models, Animal; Hemangioma, Cavernous; Humans; Laminectomy; Lidocaine; Male; Middle Aged; Pain; Pruritus; Rats; Spinal Cord Diseases; Treatment Outcome | 2005 |
Characterization of a method for measuring primary hyperalgesia of deep somatic tissue.
Topics: Animals; Arthralgia; Carrageenan; Disease Models, Animal; Functional Laterality; Hyperalgesia; Inflammation; Knee Joint; Lidocaine; Male; Morphine; Muscle, Skeletal; Nociceptors; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Skin | 2005 |
Evidence for the involvement of endogenous ATP and P2X receptors in TMJ pain.
Topics: Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; Arthralgia; Arthritis; Carrageenan; Disease Models, Animal; Down-Regulation; Lidocaine; Male; Nociceptors; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2X; Sensory Receptor Cells; Temporomandibular Joint; Temporomandibular Joint Disorders | 2005 |
Intracranial pressure changes during rapid sequence intubation: a swine model.
Topics: Animals; Brain Injuries; Cross-Over Studies; Disease Models, Animal; Emergency Treatment; Intracranial Pressure; Intubation, Intratracheal; Lidocaine; Pancuronium; Pilot Projects; Succinylcholine; Swine; Thiopental | 2005 |
A simple in vivo atrial fibrillation model of rat induced by transesophageal atrial burst pacing.
Topics: Animals; Atrial Fibrillation; Cardiac Pacing, Artificial; Disease Models, Animal; Electrocardiography; Lidocaine; Male; Rats; Rats, Sprague-Dawley | 2005 |
Local anaesthetics attenuates spinal nociception and HPA-axis activation during experimental laparotomy in pigs.
Topics: Adrenocorticotropic Hormone; Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; C-Reactive Protein; Disease Models, Animal; Female; Hydrocortisone; Hypothalamo-Hypophyseal System; Interleukin-6; Laparotomy; Lidocaine; Male; Pain; Pituitary-Adrenal System; Swine; Swine Diseases | 2005 |
Neuroprotective mechanisms of lidocaine against in vitro ischemic insult of the rat hippocampal CA1 pyramidal neurons.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Brain Infarction; Calcium Signaling; Disease Models, Animal; Dose-Response Relationship, Drug; Energy Metabolism; Excitatory Postsynaptic Potentials; Flavoproteins; Glucose; Hippocampus; Hypoxia-Ischemia, Brain; Lidocaine; Male; Membrane Potentials; Microscopy, Electron, Transmission; Mitochondria; Neuroprotective Agents; Organ Culture Techniques; Pyramidal Cells; Rats; Rats, Wistar; Recovery of Function; Synaptic Transmission | 2005 |
On the role of intramural nerves in the pathogenesis of cholera toxin-induced intestinal secretion.
Topics: Anesthetics, Local; Animals; Cats; Celiac Plexus; Cholera; Cholera Toxin; Disease Models, Animal; Female; Intestinal Secretions; Jejunum; Lidocaine; Male; Poisons; Rats; Rats, Sprague-Dawley; Tetrodotoxin | 1981 |
Impaired feedforward inhibition of the thalamocortical projection in epileptic Ca2+ channel mutant mice, tottering.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Age Factors; Animals; Calcium Channel Blockers; Calcium Channels, N-Type; Disease Models, Animal; Electric Stimulation; Electroencephalography; Epilepsy, Absence; Evoked Potentials; Excitatory Postsynaptic Potentials; Homeostasis; Lidocaine; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; omega-Agatoxin IVA; omega-Conotoxin GVIA; Patch-Clamp Techniques; Picrotoxin; Pyramidal Cells; Somatosensory Cortex; Synaptic Transmission; Thalamic Nuclei; Valine | 2006 |
Cellular basis for trigger and maintenance of ventricular fibrillation in the Brugada syndrome model: high-resolution optical mapping study.
Topics: Action Potentials; Animals; Cardiovascular Agents; Disease Models, Animal; Dogs; Electrocardiography; Electrophysiologic Techniques, Cardiac; Endocardium; Heart Conduction System; Heart Diseases; Heart Ventricles; Lidocaine; Male; Pericardium; Pinacidil; Tachycardia, Ventricular; Terfenadine; Ventricular Fibrillation | 2006 |
Antiarrhythmic activity of taurhythman.
Topics: Aconitine; Alkanesulfonic Acids; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiotonic Agents; Disease Models, Animal; Heart Arrest; Lidocaine; Male; Procainamide; Rats; Tachycardia, Paroxysmal; Ventricular Fibrillation | 2005 |
Descending facilitation from the rostral ventromedial medulla maintains visceral pain in rats with experimental pancreatitis.
Topics: Animals; Biopsy, Needle; Disease Models, Animal; Drug Interactions; Immunohistochemistry; Injections, Spinal; Lidocaine; Male; Medulla Oblongata; N-Glycosyl Hydrolases; Opioid Peptides; Pain Measurement; Pain, Intractable; Pancreatitis; Rats; Rats, Sprague-Dawley; Reference Values; Ribosome Inactivating Proteins, Type 1; Saporins; Severity of Illness Index; Spinal Nerves | 2006 |
Heterotopic inputs facilitate poststimulus afterdischarges of spinal WDR neurons in rats with chronic nerve constriction.
Topics: Action Potentials; Anesthetics, Local; Animals; Behavior, Animal; Chronic Disease; Constriction; Disease Models, Animal; Functional Laterality; Lidocaine; Male; Nerve Block; Neurons; Pain Measurement; Physical Stimulation; Rats; Rats, Sprague-Dawley; Reaction Time; Sciatic Neuropathy; Spinal Cord; Time Factors | 2006 |
Up-regulation of acid-sensing ion channel 3 in dorsal root ganglion neurons following application of nucleus pulposus on nerve root in rats.
Topics: Acid Sensing Ion Channels; Animals; Disease Models, Animal; Ganglia, Spinal; Hyperalgesia; Intervertebral Disc; Intervertebral Disc Displacement; Lidocaine; Male; Membrane Proteins; Nerve Tissue Proteins; Neurons; Rats; Rats, Sprague-Dawley; Sodium Channels; Spinal Nerve Roots; Up-Regulation | 2006 |
Context-dependent prefrontal cortex regulation of cocaine self-administration and reinstatement behaviors in rats.
Topics: Acoustic Stimulation; Anesthetics, Local; Animals; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Environment; Environment, Controlled; Lidocaine; Male; Neural Pathways; Odorants; Photic Stimulation; Prefrontal Cortex; Rats; Reward; Self Administration | 2006 |
Preemptive analgesia with lidocaine prevents Failed Back Surgery Syndrome.
Topics: Amino Acids; Analysis of Variance; Anesthetics, Local; Animals; Back Pain; Disease Models, Animal; Lidocaine; Male; Microdialysis; Pain Measurement; Rats; Rats, Sprague-Dawley; Rhizotomy; Spinal Nerve Roots; Time Factors | 2007 |
Temperature modulation of ventricular arrhythmogenicity in a canine tissue model of Brugada syndrome.
Topics: Action Potentials; Animals; Body Temperature; Brugada Syndrome; Disease Models, Animal; Dogs; Electrocardiography; Fever; Hypothermia, Induced; Lidocaine; Ventricular Dysfunction | 2007 |
How can a single mutation cause such arrhythmic havoc?
Topics: Action Potentials; Animals; Body Temperature; Brugada Syndrome; Disease Models, Animal; Dogs; Electrocardiography; Fever; Hypothermia, Induced; Ion Channels; Lidocaine; Mutation; Ventricular Dysfunction | 2007 |
Effect of prefrontal cortex inactivation on behavioral and neurochemical abnormalities in rats with excitotoxic lesions of the entorhinal cortex.
Topics: Amygdala; Anesthetics, Local; Animals; Denervation; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Entorhinal Cortex; Lidocaine; Limbic System; Male; Methamphetamine; Motor Activity; Neural Inhibition; Neural Pathways; Nucleus Accumbens; Prefrontal Cortex; Quinolinic Acid; Rats; Rats, Wistar; Schizophrenia; Synaptic Transmission | 2007 |
Involvement of substance P and calcitonin gene-related peptide in development and maintenance of neuropathic pain from spinal nerve injury model of rat.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Behavior, Animal; Calcitonin Gene-Related Peptide; Disease Models, Animal; Dose-Response Relationship, Drug; Lidocaine; Male; Neuralgia; Pain Measurement; Peptide Fragments; Quinuclidines; Rats; Rats, Sprague-Dawley; Spinal Nerves; Substance P; Time Factors | 2007 |
Limiting sarcolemmal Na+ entry during resuscitation from ventricular fibrillation prevents excess mitochondrial Ca2+ accumulation and attenuates myocardial injury.
Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Calcium; Coronary Circulation; Disease Models, Animal; Heart Ventricles; Lidocaine; Male; Mitochondria, Heart; Myocardial Reperfusion Injury; Myocardium; Rats; Rats, Sprague-Dawley; Research Design; Resuscitation; Sarcolemma; Sodium; Sodium Channel Blockers; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase; Troponin I; Ventricular Fibrillation; Ventricular Function, Left | 2007 |
Nerve terminal contributes to acetylcholine receptor organization at the dystrophic neuromuscular junction of mdx mice.
Topics: Age Factors; Animals; Disease Models, Animal; Lidocaine; Mice; Mice, Inbred mdx; Microscopy, Confocal; Muscle Denervation; Muscle, Skeletal; Muscular Dystrophy, Animal; Muscular Dystrophy, Duchenne; Neuromuscular Junction; Presynaptic Terminals; Receptor Aggregation; Receptors, Cholinergic; Regeneration | 2007 |
[Protective effects of lidocaine against lung injury after hemorrhagic shock in rabbits].
Topics: Animals; Disease Models, Animal; Lidocaine; Lung; Lung Injury; Malondialdehyde; Rabbits; Shock, Hemorrhagic; Superoxide Dismutase | 2007 |
Expression of the focal adhesion protein PINCH in normal and alkali-injured corneas and the role of PMNs.
Topics: Animals; Anticoagulants; Azepines; Burns, Chemical; Cornea; Corneal Injuries; Disease Models, Animal; DNA-Binding Proteins; Endothelium, Vascular; Eye Burns; Focal Adhesions; Immunoenzyme Techniques; Lidocaine; Neutrophils; Polysaccharides; Rabbits; Sodium Hydroxide; Wound Healing; Zinc Fingers | 2007 |
The quaternary lidocaine derivative, QX-314, produces long-lasting local anesthesia in animal models in vivo.
Topics: Action Potentials; Anesthesia, Local; Anesthetics, Local; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Intradermal Tests; Lidocaine; Mice; Nerve Block; Pain; Pain Measurement; Quaternary Ammonium Compounds; Random Allocation; Sciatic Nerve; Sciatic Neuropathy; Sodium Chloride; Survival Analysis; Time Factors | 2007 |
Restitution analysis of alternans and its relationship to arrhythmogenicity in hypokalaemic Langendorff-perfused murine hearts.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Pacing, Artificial; Disease Models, Animal; Electrocardiography; Endocardium; Fourier Analysis; Heart Rate; Hypokalemia; Lidocaine; Mice; Models, Cardiovascular; Perfusion; Pericardium; Reproducibility of Results; Time Factors | 2008 |
Lidocaine attenuates lipopolysaccharide-induced acute lung injury through inhibiting NF-kappaB activation.
Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Lidocaine; Lipopolysaccharides; Lung; Male; NF-kappa B; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome | 2008 |
Protection of cellular and mitochondrial functions against liver ischemia by N-benzyl-N'-(2-hydroxy-3,4-dimethoxybenzyl)-piperazine (BHDP), a sigma1 ligand.
Topics: Adenosine Triphosphate; Animals; Biotransformation; Cell Membrane; Cell Respiration; Cold Ischemia; Disease Models, Animal; Dose-Response Relationship, Drug; Hepatocytes; Lidocaine; Ligands; Liver; Male; Mitochondria, Liver; Piperazines; Protective Agents; Rats; Rats, Wistar; Receptors, sigma; Reperfusion Injury; Sigma-1 Receptor; Time Factors | 2008 |
Attenuating phosphorylation of p38 MAPK in the activated microglia: a new mechanism for intrathecal lidocaine reversing tactile allodynia following chronic constriction injury in rats.
Topics: Anesthetics, Local; Animals; Constriction, Pathologic; Disease Models, Animal; Hyperesthesia; Injections, Spinal; Lidocaine; Male; Microglia; Nerve Tissue Proteins; p38 Mitogen-Activated Protein Kinases; Pain Measurement; Peripheral Nervous System Diseases; Phosphorylation; Rats; Rats, Sprague-Dawley; Spinal Cord; Time Factors | 2008 |
Experimental autoimmune prostatitis induces chronic pelvic pain.
Topics: Amines; Analgesics; Anesthetics, Local; Animals; Autoimmune Diseases; Chronic Disease; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Lidocaine; Male; Mice; Mice, Inbred NOD; Nerve Fibers; Pain Measurement; Pelvic Pain; Prostate; Prostatitis; Rats; Rats, Inbred BB; Syndrome; Time Factors; Tissue Extracts | 2008 |
Effects of atrial pacing, isoprenaline and lignocaine on experimental polymorphous ventricular tachycardia.
Topics: Animals; Blood Pressure; Cardiac Pacing, Artificial; Disease Models, Animal; Dogs; Electrocardiography; Female; Heart Atria; Heart Rate; Heart Ventricles; Isoproterenol; Lidocaine; Male; Quinidine; Tachycardia | 1984 |
Antiarrhythmic and electrophysiologic actions of flecainide in animal models.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Dogs; Electrophysiology; Flecainide; Heart Conduction System; In Vitro Techniques; Lidocaine; Piperidines; Procainamide; Quinidine; Rabbits | 1984 |
[Pharmacological protection of the kidneys from ischemic damage. The effectiveness of anti-ischemia protection of the kidneys in simulating the terminal state in the donors].
Topics: Animals; Death; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Humans; Hypotension; Ischemia; Kidney; Kidney Transplantation; Lidocaine; Pentoxifylline; Prednisolone; Shock, Hemorrhagic; Tissue Donors | 1982 |
Indomethacin improves survival in gram-negative sepsis.
Topics: Animals; Blood Pressure; Disease Models, Animal; Escherichia coli Infections; Indomethacin; Leukocyte Count; Lidocaine; Male; Peritonitis; Platelet Count; Rats; Rats, Inbred Strains; Shock, Septic | 1981 |
[Pharmacologic evaluation of electrical processes in the myocardium].
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Electrophysiology; Heart; Heart Conduction System; In Vitro Techniques; Lidocaine; Nitroglycerin; Pindolol; Verapamil | 1982 |
Localization and mechanism of ventricular tachycardia by ice mapping 1 week after the onset of myocardial infarction in dogs.
Topics: Action Potentials; Animals; Atrioventricular Node; Bundle of His; Cold Temperature; Disease Models, Animal; Dogs; Electrophysiology; Lidocaine; Myocardial Infarction; Tachycardia | 1983 |
Coronary artery ligation, early arrhythmias, and determination of the ischemic area in conscious rats.
Topics: Animals; Arrhythmias, Cardiac; Coronary Disease; Coronary Vessels; Disease Models, Animal; Lidocaine; Ligation; Male; Myocardial Infarction; Pindolol; Rats; Rats, Inbred Strains | 1983 |
Acute coronary artery occlusion-reperfusion-induced arrhythmias in rats, dogs and pigs: antiarrhythmic evaluation of quinidine, procainamide and lidocaine.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Coronary Disease; Disease Models, Animal; Dogs; Female; Heart Rate; Lidocaine; Male; Perfusion; Potassium; Procainamide; Quinidine; Rats; Rats, Inbred Strains; Species Specificity; Swine | 1982 |
Studies on the preventive method of lowered ventricular fibrillation threshold during experimental acute myocardial infarctions. A comparison between disopyramide phosphate and lidocaine.
Topics: Animals; Disease Models, Animal; Disopyramide; Dogs; Dose-Response Relationship, Drug; Injections, Intramuscular; Injections, Intravenous; Lidocaine; Myocardial Infarction; Pyridines; Ventricular Fibrillation | 1981 |
Inhibition of serotonin synthesis within the medulla and posterior hypothalamus by cardiac vagal afferents during acute myocardial ischemia in the rat.
Topics: Afferent Pathways; Animals; Coronary Disease; Disease Models, Animal; Hypothalamus; Lidocaine; Male; Medulla Oblongata; Rats; Rats, Inbred Strains; Serotonin; Vagotomy; Vagus Nerve | 1981 |
[Effects of antiarrhythmic agents on ventricular arrhythmias following myocardial infarct induced with glass beads in dogs (author's transl)].
Topics: Animals; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Coronary Vessels; Disease Models, Animal; Dogs; Electrocardiography; Female; Glass; Injections, Intra-Arterial; Lidocaine; Male; Myocardial Infarction; Propranolol; Quinidine | 1981 |
Ventricular tachyarrhythmias in regional myocardial hyperkalemia: efficacy of three antiarrhythmic agents.
Topics: Animals; Coronary Disease; Disease Models, Animal; Dogs; Electrocardiography; Heart Conduction System; Heart Rate; Heart Ventricles; Lidocaine; Male; Myocardium; Potassium; Potassium Chloride; Practolol; Procainamide; Tachycardia; Ventricular Fibrillation | 1980 |
The paradoxical effect of lidocaine on an experimental model of epilepsy.
Topics: Animals; Anticonvulsants; Convulsants; Disease Models, Animal; Electric Stimulation; Electroencephalography; Epilepsy; Hippocampus; Lidocaine; Male; Rats; Time Factors | 1980 |
Coronary artery ligation in anesthetized rats as a method for the production of experimental dysrhythmias and for the determination of infarct size.
Topics: Androstanols; Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Coronary Vessels; Disease Models, Animal; Electroencephalography; Heart Rate; Lidocaine; Ligation; Male; Myocardial Infarction; Rats | 1980 |
Prophylactic lignocaine and early post-coronary artery occlusion dysrhythmias in anaesthetized greyhounds.
Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Coronary Vessels; Disease Models, Animal; Dogs; Female; Hemodynamics; Lidocaine; Male; Myocardial Infarction | 1980 |
Antiarrhythmic effects of bisaramil on triggered arrhythmias produced by intracoronary injection of digitalis and adrenaline in the dog.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bridged Bicyclo Compounds, Heterocyclic; Chlorobenzenes; Digitalis Glycosides; Disease Models, Animal; Disopyramide; Dogs; Epinephrine; Female; Flecainide; Injections, Intra-Arterial; Lidocaine; Male; Ouabain; Verapamil | 1995 |
Profibrillatory effects of lidocaine in the acutely ischemic porcine heart.
Topics: Action Potentials; Animals; Cardiac Pacing, Artificial; Coronary Disease; Disease Models, Animal; Electrocardiography; Electrophysiology; Female; Lidocaine; Male; Myocardial Ischemia; Reproducibility of Results; Swine; Ventricular Fibrillation | 1995 |
Pre-injury lidocaine treatment prevents thermal hyperalgesia and cutaneous thermal abnormalities in a rat model of peripheral neuropathy.
Topics: Animals; Disease Models, Animal; Hyperalgesia; Lidocaine; Ligation; Male; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Skin Temperature | 1995 |
Effect of levamisole hydrochloride on the guinea-pig atrium.
Topics: Animals; Arrhythmias, Cardiac; Atropine; Disease Models, Animal; Drug Antagonism; Drug Evaluation, Preclinical; Electric Stimulation; Female; Guinea Pigs; Heart Atria; Hexamethonium; In Vitro Techniques; Levamisole; Lidocaine; Male; Practolol; Verapamil | 1993 |
Spinal cord amino acid release and content in an arthritis model: the effects of pretreatment with non-NMDA, NMDA, and NK1 receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Arthritis; Biphenyl Compounds; Disease Models, Animal; Glutamates; Glutamic Acid; Immunohistochemistry; Lidocaine; Male; Microdialysis; Neurokinin-1 Receptor Antagonists; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1993 |
Epidural anesthesia accelerates the recovery of postischemic bowel motility in the rat.
Topics: Anesthesia, Epidural; Animals; Disease Models, Animal; Gastrointestinal Motility; Intestines; Ischemia; Lidocaine; Male; Rats; Rats, Inbred Strains; Sodium Chloride | 1994 |
Study of the sensitivity of the diabetes-induced pain model in rats to a range of analgesics.
Topics: Analgesics; Animals; Antidepressive Agents, Tricyclic; Aspirin; Clonidine; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Models, Animal; Humans; Lidocaine; Male; Morphine; Pain; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity | 1994 |
An in vitro method for the evaluation of antiarrhythmic and antiischemic agents by using programmed electrical stimulation of rabbit heart.
Topics: Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Electric Stimulation; Glycine; Heart; Heart Ventricles; In Vitro Techniques; Lidocaine; Myocardial Ischemia; Myocardial Reperfusion Injury; Rabbits; Sotalol; Ventricular Function | 1994 |
The relationship between regional blood flow and absorption of lignocaine.
Topics: Absorption; Animals; Disease Models, Animal; Epinephrine; Forelimb; Half-Life; Hindlimb; Injections, Intramuscular; Injections, Intravenous; Lidocaine; Muscles; Regional Blood Flow; Sheep; Sodium Pertechnetate Tc 99m | 1993 |
Effects of amiodarone on refractory ventricular fibrillation in acute myocardial infarction: experimental study.
Topics: Amiodarone; Animals; Disease Models, Animal; Dogs; Electric Stimulation; Epinephrine; Female; Heart Conduction System; Heart Rate; Hemodynamics; Injections, Intravenous; Lidocaine; Male; Myocardial Infarction; Ventricular Fibrillation | 1994 |
Antifibrillatory and electrophysiologic actions of moricizine alone and in combination with lidocaine: a prospective, randomized trial.
Topics: Animals; Blood Pressure; Disease Models, Animal; Double-Blind Method; Electrocardiography; Lidocaine; Moricizine; Prospective Studies; Random Allocation; Swine; Ventricular Fibrillation | 1993 |
Halothane and the reperfusion injury in the intact animal model.
Topics: Animals; Arrhythmias, Cardiac; Disease Models, Animal; Dose-Response Relationship, Drug; Halothane; Heart; Hemodynamics; Lidocaine; Myocardial Ischemia; Myocardial Reperfusion Injury; Swine; Systole; Ventricular Function | 1993 |
Effects of a new amiodarone-like agent, SR 33589, in comparison to amiodarone, D,L-sotalol, and lignocaine, on ischemia-induced ventricular arrhythmias in anesthetized pigs.
Topics: Amiodarone; Analysis of Variance; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzofurans; Death, Sudden, Cardiac; Disease Models, Animal; Dronedarone; Female; Lidocaine; Male; Myocardial Ischemia; Sotalol; Stereoisomerism; Swine; Tachycardia, Ventricular; Ventricular Fibrillation | 1995 |
SR 33589, a new amiodarone-like agent: effect on ischemia- and reperfusion-induced arrhythmias in anesthetized rats.
Topics: Administration, Oral; Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzofurans; Chi-Square Distribution; Disease Models, Animal; Dose-Response Relationship, Drug; Dronedarone; Electrocardiography; Heart Block; Heart Rate; Injections, Intravenous; Lidocaine; Myocardial Reperfusion Injury; Random Allocation; Rats; Sotalol; Ventricular Fibrillation | 1995 |
Lidocaine reduces reperfusion injury and neutrophil migration in canine lung allografts.
Topics: Animals; CD11 Antigens; Cell Adhesion; Chemotaxis, Leukocyte; Disease Models, Animal; Dogs; Flow Cytometry; Fluorescent Antibody Technique; Lidocaine; Lung Transplantation; Neutrophils; Reperfusion Injury; Transplantation, Homologous | 1996 |
Neurological decompression illness in swine.
Topics: Animals; Decompression Sickness; Disease Models, Animal; Lidocaine; Male; Purpura; Skin; Spinal Cord; Swine | 1996 |
Extrahepatic metabolism of 4-methylumbelliferone and lidocaine in the anhepatic rabbit.
Topics: Anesthetics, Local; Animals; Disease Models, Animal; Hepatectomy; Hymecromone; Indicators and Reagents; Lidocaine; Rabbits; Umbelliferones | 1996 |
Pressure-heart rate relationship in intact and after stepwise elimination of three major baroreflex loops in dogs.
Topics: Action Potentials; Adjuvants, Anesthesia; Anesthetics, Local; Animals; Aorta; Arteriosclerosis; Baroreflex; Blood Pressure; Carotid Sinus; Disease Models, Animal; Dogs; Feedback; Heart Rate; Hypertension; Lidocaine; Linear Models; Nerve Block; Nitroprusside; Pentobarbital; Phenylephrine; Pressoreceptors; Reproducibility of Results; Vasoconstrictor Agents; Vasodilator Agents | 1996 |
Lidocaine in the rostroventromedial medulla and the periaqueductal gray attenuates allodynia in neuropathic rats.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Lidocaine; Male; Medulla Oblongata; Motor Neuron Disease; Periaqueductal Gray; Rats; Rats, Wistar; Sensory Thresholds | 1996 |
Spinal somatosensory evoked potentials after epidural isoproterenol in awake sheep.
Topics: Adrenergic beta-Agonists; Anesthesia, Epidural; Anesthetics, Local; Animals; Disease Models, Animal; Electric Stimulation; Evoked Potentials, Somatosensory; Female; Follow-Up Studies; Injections, Epidural; Isoproterenol; Lidocaine; Neural Pathways; Reaction Time; Sciatic Nerve; Sheep; Spinal Cord; Wakefulness | 1997 |
Effects of lidocaine on salicylate-induced discharge of neurons in the inferior colliculus of the guinea pig.
Topics: Action Potentials; Anesthetics, Local; Animals; Auditory Pathways; Disease Models, Animal; Electrophysiology; Female; Guinea Pigs; Humans; Inferior Colliculi; Lidocaine; Neurons; Salicylates; Salicylic Acid; Tinnitus | 1997 |
Susceptibility of isolated rat facial nerve to anaerobic stress.
Topics: Action Potentials; Anaerobiosis; Anesthetics, Local; Animals; Anticonvulsants; Cyanides; Disease Models, Animal; Disease Susceptibility; Facial Nerve; Facial Paralysis; Glucose; Hypoxia; Ischemia; Lidocaine; Male; Membrane Potentials; Neural Conduction; Neuroprotective Agents; Nitrogen; Phenytoin; Rats; Rats, Wistar; Reaction Time | 1997 |
The effect of the sodium channel blocker QX-314 on recovery after acute spinal cord injury.
Topics: Anesthetics, Local; Animals; Disease Models, Animal; Female; Lidocaine; Rats; Rats, Wistar; Spinal Cord Injuries; Time Factors | 1997 |
Effects of lidocaine and diltiazem on recovery of electrophysiologic activity during partial reperfusion following severe myocardial ischemia in canine hearts.
Topics: Animals; Anti-Arrhythmia Agents; Blood Flow Velocity; Coronary Vessels; Diltiazem; Disease Models, Animal; Dogs; Electrocardiography; Heart Conduction System; Infusions, Intravenous; Lidocaine; Myocardial Ischemia; Myocardial Reperfusion Injury; Random Allocation; Tachycardia, Ventricular; Treatment Outcome; Vasodilator Agents | 1997 |
Effects of lidocaine, ajmaline, and diltiazem on ventricular defibrillation energy requirements in isolated rabbit heart.
Topics: Ajmaline; Analysis of Variance; Animals; Anti-Arrhythmia Agents; Cardiovascular Agents; Defibrillators, Implantable; Diltiazem; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Countershock; Electrocardiography; Equipment Failure; Female; Heart; In Vitro Techniques; Lidocaine; Male; Rabbits; Ventricular Fibrillation | 1997 |
[Effect of lidocaine on ultrastructural changes in jejunum, kidney medulla and lungs of suckling rabbits, caused by vibrio cholerae].
Topics: Anesthetics, Local; Animals; Animals, Newborn; Cholera; Cytoplasm; Dinoprostone; Disease Models, Animal; Enterochromaffin Cells; Jejunum; Kidney Medulla; Lidocaine; Lung; Phospholipases A; Rabbits; Serotonin; Vibrio cholerae | 1997 |
Auditory evoked responses under total spinal anesthesia in rats.
Topics: Action Potentials; Anesthesia, Spinal; Anesthetics, Local; Animals; Auditory Pathways; Cochlear Microphonic Potentials; Cochlear Nerve; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Monitoring; Evoked Potentials, Auditory, Brain Stem; Lidocaine; Male; Rats; Rats, Wistar | 1997 |
Effects of intravenous lipid as a source of energy in parenteral nutrition associated hepatic dysfunction and lidocaine elimination: a study using isolated rat liver perfusion.
Topics: Amino Acids; Animals; Biomarkers; Body Weight; Chromatography, High Pressure Liquid; Disease Models, Animal; Fat Emulsions, Intravenous; Fatty Liver; Glucose; Hydroxylation; In Vitro Techniques; Injections, Intravenous; Lidocaine; Liver; Male; Organ Size; Parenteral Nutrition; Perfusion; Random Allocation; Rats; Rats, Sprague-Dawley | 1997 |
Drug-induced vasodilation: in vitro and in vivo study on the effects of lidocaine and papaverine on rabbit carotid artery.
Topics: Animals; Carotid Arteries; Disease Models, Animal; Dose-Response Relationship, Drug; In Vitro Techniques; Lidocaine; Male; Papaverine; Rabbits; Reference Values; Vasodilation; Vasodilator Agents | 1998 |
Relationship between action potential, contraction-relaxation pattern, and intracellular Ca2+ transient in cardiomyocytes of dogs with chronic heart failure.
Topics: Action Potentials; Animals; Calcium; Cells, Cultured; Disease Models, Animal; Dogs; Electrophysiology; Heart; Heart Failure; Lidocaine; Muscle Contraction; Saxitoxin | 1998 |
Cellular mechanisms underlying spontaneous interictal spikes in an acute model of focal cortical epileptogenesis.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Acute Disease; Animals; Bicuculline; Brain; Cerebral Cortex; Disease Models, Animal; Epilepsies, Partial; Functional Laterality; Glutamic Acid; Guinea Pigs; In Vitro Techniques; Lidocaine; Membrane Potentials; Reaction Time; Synaptic Transmission | 1999 |
High extracellular K+ during hypoxic preconditioning episodes attenuates the post-ischemic contractile and ionic benefits of preconditioning.
Topics: Animals; Calcium; Disease Models, Animal; Dose-Response Relationship, Drug; Edetic Acid; Hypoxia; Ischemia; Ischemic Preconditioning, Myocardial; Lidocaine; Male; Perfusion; Potassium; Rats; Rats, Wistar; Reperfusion; Sarcolemma; Time Factors; Ventricular Pressure | 1999 |
Selective protection of gray and white matter during spinal cord ischemic injury.
Topics: Animals; Brain; Disease Models, Animal; Evaluation Studies as Topic; Excitatory Amino Acid Antagonists; Injections, Spinal; Ischemia; Lidocaine; Male; Paraplegia; Piperazines; Random Allocation; Rats; Rats, Sprague-Dawley; Sodium Chloride; Spinal Cord; Time Factors | 1999 |
Lidocaine attenuates acute lung injury induced by a combination of phospholipase A2 and trypsin.
Topics: Animals; Blood Gas Analysis; Disease Models, Animal; Disease Progression; Drug Evaluation, Preclinical; Infusions, Intravenous; Leukocyte Count; Lidocaine; Male; Neutrophils; Organ Size; Phospholipases A; Phospholipases A2; Platelet Count; Rabbits; Random Allocation; Respiration, Artificial; Respiratory Distress Syndrome; Respiratory Mechanics; Trypsin | 2000 |
[Antiarrhythmic effects of pilsicainide hydrochloride and effects on cardiac function and ECG in dogs: comparison with disopyramide].
Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Vessels; Disease Models, Animal; Disopyramide; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Female; Hemodynamics; Infusions, Intravenous; Lidocaine; Ligation | 2000 |
[Effect of mexiletine on spontaneous sensory afferent activity in spontaneous diabetic rats (WBN/Kob rats)].
Topics: Action Potentials; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Depression, Chemical; Diabetes Complications; Diabetes Mellitus; Diabetic Neuropathies; Disease Models, Animal; Lidocaine; Mexiletine; Nerve Fibers; Neurons, Afferent; Peripheral Nervous System Diseases; Rats; Rats, Inbred Strains; Rats, Wistar | 2000 |
Effects of sodium channel blockade on ibutilide induced prolongation of repolarization in the isolated rabbit ventricle.
Topics: Action Potentials; Analysis of Variance; Animals; Anti-Arrhythmia Agents; Culture Techniques; Disease Models, Animal; Electric Conductivity; Female; Heart Ventricles; Lidocaine; Male; Probability; Rabbits; Reference Values; Sodium Channel Blockers; Sulfonamides; Tetrodotoxin; Ventricular Function | 2000 |
Lack of pre-emptive analgesic effects of local anaesthetics on neuropathic pain.
Topics: Anesthetics, Local; Animals; Bupivacaine; Disease Models, Animal; Lidocaine; Male; Pain Threshold; Pain, Postoperative; Rats; Rats, Sprague-Dawley; Spinal Nerves | 2000 |
Topical iodine preparation as therapy against sulfur mustard-induced skin lesions.
Topics: Administration, Topical; Animals; Anti-Infective Agents, Local; Dermatologic Agents; Disease Models, Animal; Drug Interactions; Guinea Pigs; Irritants; Lidocaine; Male; Mustard Gas; Povidone-Iodine; Skin; Skin Diseases; Time Factors | 2000 |
Treatment of skin injuries induced by sulfur mustard with calmodulin antagonists, using the pig model.
Topics: Administration, Topical; Anesthetics, Local; Animals; Blister; Calmodulin; Dermatologic Agents; Disease Models, Animal; Dopamine Antagonists; Female; Injections, Intradermal; Lidocaine; Mustard Gas; Procaine; Swine; Thioridazine; Trifluoperazine | 2000 |
Reassessment of monoethylglycinexylidide as preoperative liver function test in a rat model of liver cirrhosis and man.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bilirubin; Disease Models, Animal; Hepatectomy; Hepatitis; Hepatitis C, Chronic; Humans; Indicators and Reagents; Indocyanine Green; Lidocaine; Liver; Liver Cirrhosis; Liver Cirrhosis, Experimental; Liver Function Tests; Male; Organic Chemicals; Prothrombin Time; Rats; Rats, Wistar; Regression Analysis; Serum Albumin; Thioacetamide | 2001 |
Measurement of the glucose transport time delay between the blood and aqueous humor of the eye for the eventual development of a noninvasive glucose sensor.
Topics: Anesthetics, Local; Animals; Aqueous Humor; Biological Transport; Blood Glucose; Blood Glucose Self-Monitoring; Diabetes Mellitus; Disease Models, Animal; Glucose; Lidocaine; Osmolar Concentration; Rabbits; Time Factors | 2001 |
The midline thalamus: alterations and a potential role in limbic epilepsy.
Topics: Anatomy, Cross-Sectional; Animals; Cell Count; Disease Models, Animal; Electric Stimulation; Electrodes, Implanted; Epilepsy, Temporal Lobe; Hippocampus; Kindling, Neurologic; Lidocaine; Limbic System; Male; Neural Pathways; Neurons; Rats; Rats, Sprague-Dawley; Thalamic Nuclei; Thalamus | 2001 |
Effects of lidocaine on blood flow and endoneurial fluid pressure in a rat model of herniated nucleus pulposus.
Topics: Anesthetics, Local; Animals; Disease Models, Animal; Extracellular Space; Female; Ganglia, Spinal; Hindlimb; Intervertebral Disc; Intervertebral Disc Displacement; Lidocaine; Peripheral Nerves; Pressure; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Spinal Nerves | 2001 |
Development of a behavioral model of TMJ pain in rats: the TMJ formalin test.
Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Behavior, Animal; Disease Models, Animal; Lidocaine; Male; Morphine; Nociceptors; Pain; Pain Measurement; Rats; Rats, Wistar; Temporomandibular Joint | 2001 |
Involvement of the central nervous system in the protective effect of melanocortins in myocardial ischaemia/reperfusion injury.
Topics: Adrenocorticotropic Hormone; Animals; Central Nervous System; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Injections, Intravenous; Injections, Intraventricular; Lidocaine; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Probability; Rats; Rats, Wistar; Reference Values; Sensitivity and Specificity; Sodium Chloride; Survival Analysis | 2002 |
Dissociable effects of lidocaine inactivation of the rostral and caudal basolateral amygdala on the maintenance and reinstatement of cocaine-seeking behavior in rats.
Topics: Acoustic Stimulation; Amygdala; Anesthetics, Local; Animals; Behavior, Animal; Cocaine-Related Disorders; Conditioning, Psychological; Cues; Discrimination Learning; Disease Models, Animal; Extinction, Psychological; Feeding Behavior; Injections, Intravenous; Lidocaine; Male; Photic Stimulation; Rats; Rats, Wistar; Recurrence; Self Administration | 2002 |
Stimulus-response functions of the lateral dorsal striatum and regulation of behavior studied in a cocaine maintenance/cue reinstatement model in rats.
Topics: Acoustic Stimulation; Anesthetics, Local; Animals; Association Learning; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Cues; Discrimination Learning; Disease Models, Animal; Dose-Response Relationship, Drug; Extinction, Psychological; Infusions, Intravenous; Lidocaine; Male; Photic Stimulation; Rats; Rats, Wistar; Reinforcement Schedule; Self Administration; Time Factors | 2002 |
Continual systemic infusion of lidocaine provides analgesia in an animal model of neuropathic pain.
Topics: Anesthetics, Local; Animals; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Infusion Pumps, Implantable; Lidocaine; Ligation; Male; Rats; Rats, Sprague-Dawley; Sciatica | 2002 |
Effects of lidocaine on the electrophysiological properties of subendocardial Purkinje fibers surviving acute myocardial infarction.
Topics: Animals; Disease Models, Animal; Dogs; Electrophysiology; Heart Conduction System; Heart Ventricles; In Vitro Techniques; Lidocaine; Male; Membrane Potentials; Myocardial Infarction; Purkinje Fibers | 1979 |
The effects of lidocaine on hyperoxic seizure activity in the rat.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hyperbaric Oxygenation; Lidocaine; Rats; Seizures | 1978 |
Arterial hypertension induced by femoral lengthening. A canine model.
Topics: Anesthesia, Spinal; Animals; Blood Pressure; Bone Lengthening; Disease Models, Animal; Dogs; Femur; Hypertension; Lidocaine; Phenoxybenzamine; Propranolol; Reserpine; Sciatic Nerve; Sympathetic Nervous System; Trimethaphan | 1978 |
A comparison of immunologic asthma to two types of cholinergic respiratory responses in the rhesus monkey.
Topics: Acetylcholine; Aerosols; Airway Resistance; Animals; Antigens; Ascaris; Asthma; Atropine; Carbachol; Cholinergic Fibers; Disease Models, Animal; Female; Haplorhini; Lidocaine; Macaca mulatta; Male; Peak Expiratory Flow Rate; Physostigmine; Respiration; Vagus Nerve | 1976 |
Reduction of ischemic myocardial damage in the dog by lidocaine infusion.
Topics: Animals; Biopsy; Body Temperature; Cardiopulmonary Bypass; Coronary Disease; Disease Models, Animal; Dogs; Heart Arrest; Infusions, Parenteral; Lidocaine; Mitochondria, Muscle; Mitochondrial Swelling; Myocardium; Time Factors | 1977 |
Proceedings: Effects of barbiturates on blood pressure in lidocaine hydrochloride injected SHR.
Topics: Animals; Barbiturates; Blood Pressure; Disease Models, Animal; Drug Therapy, Combination; Female; Hypertension; Lidocaine; Male; Premedication; Rats | 1976 |
Pharmacological modification of arrhythmias after experimentally induced acute myocardial infarction. Drugs acting on the nervous system.
Topics: Acute Disease; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Compounds; Chlordiazepoxide; Death, Sudden; Diazepam; Digitalis Glycosides; Disease Models, Animal; Dogs; Lidocaine; Myocardial Infarction; Propranolol | 1975 |
Effects of SUN-1165, N-(2,6-dimethylphenyl)-8-pyrrolizidine acetamide hydrochloride hemihydrate, a new class I antiarrhythmic drug, on ventricular arrhythmias, intraventricular conduction, and the refractory period in canine myocardial infarction.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Dogs; Electric Stimulation; Electrocardiography; Heart Conduction System; Lidocaine; Myocardial Infarction; Refractory Period, Electrophysiological; Ventricular Function | 1992 |
Concentration-dependent effects of lidocaine on corneal epithelial wound healing.
Topics: Animals; Cell Division; Cell Movement; Cornea; Disease Models, Animal; Dose-Response Relationship, Drug; Epithelium; Fluorophotometry; Lidocaine; Organ Culture Techniques; Rabbits; Wound Healing | 1992 |
Monoethylglycinexylidide production parallels changes in hepatic blood flow and oxygen delivery in lung injury managed with positive end-expiratory pressure.
Topics: Animals; Blood Flow Velocity; Critical Illness; Disease Models, Animal; Dogs; Evaluation Studies as Topic; Female; Hemodynamics; Injections, Intravenous; Lidocaine; Liver Circulation; Male; Oxygen Consumption; Positive-Pressure Respiration; Respiratory Distress Syndrome | 1992 |
A canine model for studying laryngospasm and its prevention.
Topics: Administration, Topical; Anesthesia, Inhalation; Animals; Clinical Protocols; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Female; Laryngismus; Lidocaine | 1992 |
Effect of lidocaine on somatosensory evoked response and cerebral blood flow after canine cerebral air embolism.
Topics: Animals; Blood Pressure; Brain Ischemia; Cerebrovascular Circulation; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Embolism, Air; Evoked Potentials, Somatosensory; Heart Rate; Intracranial Embolism and Thrombosis; Lidocaine; Male; Norepinephrine | 1992 |
Vasodepressor reaction induced by inferior vena caval occlusion and isoproterenol.
Topics: Animals; Atropine; Disease Models, Animal; Drug Administration Routes; Heart Rate; Hypotension; Infusions, Intravenous; Isoproterenol; Lidocaine; Male; Muscle Contraction; Muscle, Smooth, Vascular; Oxidopamine; Pericardium; Rats; Rats, Wistar; Stellate Ganglion; Syncope; Thrombophlebitis; Time Factors; Vagotomy; Vena Cava, Inferior | 1992 |
Effects of flecainide on ventricular arrhythmias, abnormal automaticity and activation in a canine model of myocardial infarction.
Topics: Animals; Arrhythmias, Cardiac; Disease Models, Animal; Dogs; Electrocardiography; Flecainide; Heart Rate; Heart Ventricles; Injections, Intravenous; Lidocaine; Myocardial Infarction | 1992 |
Isolated paced guinea pig left atrium: a new ouabain-induced arrhythmia model.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Function, Left; Clonidine; Disease Models, Animal; Drug Evaluation; Female; Guinea Pigs; In Vitro Techniques; Lidocaine; Male; Ouabain; Propranolol; Reproducibility of Results | 1991 |
Studies in autotomy: its pathophysiology and usefulness as a model of chronic pain.
Topics: Afferent Pathways; Animals; Behavior, Animal; Chronic Disease; Denervation; Disease Models, Animal; Electrophysiology; Ethanol; Infusion Pumps, Implantable; Lidocaine; Male; Muscles; Pain; Rats; Rats, Inbred Strains; Sciatic Nerve | 1991 |
Selective 3-hydroxylation deficiency of lidocaine and its metabolite in Dark Agouti rats.
Topics: Animals; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Disease Models, Animal; Female; Hydroxylation; Lidocaine; Male; Microsomes, Liver; Mixed Function Oxygenases; Rats; Rats, Inbred Strains | 1991 |
The role of lidocaine, epinephrine, and flap elevation in wound healing after chemical peel.
Topics: Animals; Chemexfoliation; Cicatrix; Disease Models, Animal; Epinephrine; Humans; Lidocaine; Rats; Rats, Inbred Strains; Skin; Wound Healing | 1991 |
Cocaine-base smoking in rhesus monkeys: reinforcing and physiological effects.
Topics: Animals; Blood Pressure; Cocaine; Disease Models, Animal; Dose-Response Relationship, Drug; Heart Rate; Humans; Lidocaine; Macaca mulatta; Male; Reinforcement, Psychology; Smoking; Substance-Related Disorders | 1990 |
Bretylium tosylate versus lidocaine in experimental cardiac arrest.
Topics: Animals; Bretylium Tosylate; Disease Models, Animal; Dogs; Electric Countershock; Heart Arrest; Hemodynamics; Lidocaine; Sodium Chloride; Stroke Volume; Ventricular Fibrillation | 1990 |
Inducible monomorphic sustained ventricular tachycardia in the conscious pig.
Topics: Animals; Coronary Vessels; Disease Models, Animal; Heart Ventricles; Hemodynamics; Lidocaine; Ligation; Magnesium; Metoprolol; Myocardial Infarction; Procainamide; Swine; Tachycardia | 1990 |
Ventricular arrhythmias following one-stage and two-stage coronary reperfusion: evidence for both reentry and enhanced automaticity.
Topics: Animals; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Cardiac Pacing, Artificial; Coronary Circulation; Coronary Disease; Disease Models, Animal; Dogs; Electrocardiography; Heart Atria; Heart Rate; Heart Ventricles; Lidocaine; Tachycardia; Vagus Nerve; Ventricular Fibrillation | 1985 |
Development of an in vivo model for assessment of drug-induced vascular injury.
Topics: Animals; Diazepam; Disease Models, Animal; Ear; Female; Infusions, Intravenous; Lidocaine; Male; Premedication; Rabbits; Sodium Chloride; Thrombophlebitis; Veins | 1989 |
Acute induction of sustained ventricular tachycardia: a new porcine model.
Topics: Animals; Disease Models, Animal; Electric Stimulation; Electrocardiography; Heart; Heart Ventricles; Lidocaine; Myocardial Infarction; Sotalol; Swine; Tachycardia; Time Factors; Ventricular Fibrillation | 1989 |
Role of noradrenergic system in limbic seizures induced by pilocarpine. I. Importance of beta-adrenergic receptor.
Topics: Albuterol; Animals; Disease Models, Animal; Lidocaine; Limbic System; Male; Pilocarpine; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Seizures | 1988 |
Model of electrocardiographic changes seen with subarachnoid hemorrhage in rabbits.
Topics: Animals; Arrhythmias, Cardiac; Dinoprost; Disease Models, Animal; Electrocardiography; Injections; Lidocaine; Models, Cardiovascular; Rabbits; Radiography; Skull; Subarachnoid Hemorrhage; Subarachnoid Space | 1989 |
[Croton oil-induced hemorrhoid model in rat: comparison of anti-inflammatory activity of diflucortolone valerate with other glucocorticoids].
Topics: Animals; Anti-Inflammatory Agents; Croton Oil; Diflucortolone; Disease Models, Animal; Drug Combinations; Fluocortolone; Hemorrhoids; Hydrocortisone; Lidocaine; Male; Rats; Rats, Inbred Strains; Rectum | 1988 |
[Neriproct: its anti-inflammatory effect on an experimentally induced hemorrhoid model in the rat].
Topics: Animals; Anti-Inflammatory Agents; Croton Oil; Diflucortolone; Disease Models, Animal; Dosage Forms; Drug Combinations; Fluocortolone; Hemorrhoids; Lidocaine; Male; Rats; Rats, Inbred Strains; Rectum | 1988 |
Effects of lidocaine infusion in cats after unilateral labyrinthectomy.
Topics: Adaptation, Physiological; Animals; Cats; Disease Models, Animal; Ear, Inner; Electronystagmography; Eye Movements; Infusions, Intravenous; Lidocaine; Time Factors; Vertigo; Vestibule, Labyrinth | 1988 |
Electrical and contractile behavior of large intestinal musculature of piebald mouse model for Hirschsprung's disease.
Topics: Animals; Disease Models, Animal; Electric Stimulation; Epinephrine; Hirschsprung Disease; Intestine, Large; Lidocaine; Membrane Potentials; Mice; Mice, Mutant Strains; Microelectrodes; Muscle Contraction; Tetrodotoxin; Time Factors; Transducers, Pressure | 1986 |
Ventricular fibrillation threshold in canine hearts with quinidine induced prolonged QT interval: effects of atrial pacing, isoproterenol, and lignocaine.
Topics: Animals; Cardiac Pacing, Artificial; Disease Models, Animal; Dogs; Female; Heart; Isoproterenol; Lidocaine; Male; Quinidine; Tachycardia; Ventricular Fibrillation | 1986 |
Spinal Wada test.
Topics: Animals; Disease Models, Animal; Embolization, Therapeutic; Lidocaine; Macaca mulatta; Pentobarbital; Spinal Cord | 1986 |
Resolution of experimental microvascular spasm and improvement in anastomotic patency by direct topical agent application.
Topics: Administration, Topical; Animals; Chlorpromazine; Disease Models, Animal; Drug Evaluation; Epinephrine; Lidocaine; Male; Muscle Contraction; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains; Spasm; Tail; Time Factors; Vascular Diseases; Vasoconstriction; Vasodilator Agents | 1986 |
The effect of antiarrhythmic drugs on life-threatening arrhythmias induced by the interaction between acute myocardial ischemia and sympathetic hyperactivity.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cats; Coronary Disease; Disease Models, Animal; Electrocardiography; Hemodynamics; Lidocaine; Mexiletine; Prazosin; Propranolol; Stellate Ganglion | 1985 |
Inhomogeneity of ventricular refractory period in canine heart with quinidine-induced long QT interval: a comparative study on effects of heart rate, isoprenaline, and lignocaine.
Topics: Animals; Disease Models, Animal; Dogs; Electric Stimulation; Female; Heart; Heart Rate; Isoproterenol; Lidocaine; Male; Quinidine; Tachycardia | 1985 |
Lidocaine in experimental epilepsy: correlation of anticonvulsant effect with blood concentrations.
Topics: Animals; Anticonvulsants; Cats; Disease Models, Animal; Electroencephalography; Epilepsy; Female; Injections, Intramuscular; Injections, Intravenous; Lidocaine; Male; Penicillins | 1973 |
Diazepam prevents and aborts lidocaine convulsions in monkeys.
Topics: Animals; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Haplorhini; Injections, Intramuscular; Injections, Intravenous; Lidocaine; Macaca; Male; Preanesthetic Medication; Seizures; Time Factors | 1974 |
Anti-arrhythmic effects of lidocaine metabolites.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Drug Evaluation; Ethylamines; Guinea Pigs; Heart Atria; Lidocaine; Male; Methylamines; Ouabain | 1974 |
Local anesthesia and experimental epilepsy.
Topics: Animals; Benzocaine; Cats; Disease Models, Animal; Female; Lidocaine; Male; Procaine; Seizures; Time Factors | 1974 |
Experimental model for study of "sudden death" from ventricular fibrillation or asystole.
Topics: Angiocardiography; Animals; Aorta, Thoracic; Arrhythmias, Cardiac; Autopsy; Coronary Angiography; Coronary Vessels; Death, Sudden; Diet, Atherogenic; Disease Models, Animal; Electrocardiography; Heart; Heart Conduction System; Lidocaine; Lung; Male; Myocardium; Propylthiouracil; Radiation Effects; Swine; Ventricular Fibrillation | 1973 |
The prevention of ethanol withdrawal seizures in mice by lidocaine.
Topics: Alcoholism; Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Lidocaine; Mice; Seizures; Substance Withdrawal Syndrome | 1973 |
Relationships between increased automaticity and depressed conduction in the main intraventricular conducting fascicles of the human and canine heart.
Topics: Aged; Animals; Bundle-Branch Block; Carotid Sinus; Disease Models, Animal; Dogs; Electrocardiography; Female; Heart Conduction System; Humans; Isoproterenol; Lidocaine; Pacemaker, Artificial; Time Factors; Vagus Nerve | 1974 |
Antiarrhythmic and circulatory effects of Astra W36095, a new lidocaine-like agent.
Topics: Anilides; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Chemical Phenomena; Chemistry; Chromatography, Gas; Coronary Circulation; Depression, Chemical; Disease Models, Animal; Electrocardiography; Ethylamines; Half-Life; Heart; Heart Rate; Heart Ventricles; Hemodynamics; Ischemia; Lidocaine; Regional Blood Flow; Time Factors | 1974 |
Letter: Effect of lidocaine on "gating" mechanism.
Topics: Animals; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Heart; Heart Conduction System; Heart Rate; Heart Ventricles; Humans; Lidocaine; Ventricular Fibrillation | 1974 |
Antiarrhythmic effects in dogs of lidocaine administered orally and intravenously.
Topics: Administration, Oral; Animals; Arrhythmias, Cardiac; Blood Pressure; Coronary Vessels; Disease Models, Animal; Dogs; Electrocardiography; Female; Heart Rate; Heart Ventricles; Injections, Intravenous; Lidocaine; Ligation; Male; Time Factors | 1972 |
Observations on models used for the evaluation of antiarrhythmic drugs.
Topics: Alkaloids; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Atropine; Benzazepines; Bretylium Compounds; Chlorpheniramine; Diazepam; Disease Models, Animal; Dogs; Drug Antagonism; Guinea Pigs; Imipramine; Ketones; Lidocaine; Male; Meperidine; Mephentermine; Ouabain; Phentolamine; Phenytoin; Procainamide; Promazine; Promethazine; Propranolol; Quinidine | 1971 |
[Lysis of mechanically produced spasms of small arteries through local drug administration].
Topics: Animals; Chlorpromazine; Disease Models, Animal; Lidocaine; Rabbits; Renal Artery; Spasm; Vascular Diseases; Vasodilator Agents; Vasomotor System | 1971 |
A comparison of the effects of bretylium, lignocaine and propranolol on experimental cardiac arrhythmias.
Topics: Animals; Arrhythmias, Cardiac; Bretylium Compounds; Disease Models, Animal; Dogs; Epinephrine; Lidocaine; Ouabain; Propranolol | 1969 |
Experimental myocardial infarction in calves. Coronary embolization and vessel occlusion.
Topics: Animals; Blood Pressure; Cattle; Coronary Vessels; Disease Models, Animal; Electrocardiography; Embolism; Heart; Lidocaine; Magnetics; Male; Methods; Myocardial Infarction; Myocardium; Plastics | 1971 |