lidocaine has been researched along with Disease Exacerbation in 11 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lidocaine is a local anesthetic and anti‑arrhythmic drug, and has been reported to possess anti‑tumor properties." | 5.51 | Lidocaine inhibits the progression of retinoblastoma in vitro and in vivo by modulating the miR‑520a‑3p/EGFR axis. ( Mu, X; Wang, L; Xia, W; Yu, D; Zhou, X, 2019) |
| " In case of liver cirrhosis, only Child-Pugh-Turcott A patients with normal bilirubin levels and without portal hypertension should be considered for liver resection." | 4.84 | [Liver function test to predict hepatic failure after liver resection--expensive and without clinical relevance?]. ( Galle, PR; Kanzler, S; Teufel, A, 2007) |
| "Lipedema is a chronic, progressive disorder of subcutaneous adipose tissue that usually affects the lower extremities of women." | 1.56 | Prevention of Progression of Lipedema With Liposuction Using Tumescent Local Anesthesia: Results of an International Consensus Conference. ( Anderhuber, F; Barsch, M; Faulhaber, J; Habbema, L; Halk, AB; Hanke, CW; Herbst, K; Maier, S; Mindt, S; Moosbauer, W; Pilsl, U; Podda, M; Rapprich, S; Sandhofer, M; Sattler, G; Sattler, S; Schauer, P; Schmeller, W, 2020) |
| "Lidocaine is a local anesthetic and anti‑arrhythmic drug, and has been reported to possess anti‑tumor properties." | 1.51 | Lidocaine inhibits the progression of retinoblastoma in vitro and in vivo by modulating the miR‑520a‑3p/EGFR axis. ( Mu, X; Wang, L; Xia, W; Yu, D; Zhou, X, 2019) |
| "Erythromelalgia has not been well characterized in the pediatric population." | 1.38 | Pediatric erythromelalgia: a retrospective review of 32 cases evaluated at Mayo Clinic over a 37-year period. ( Cook-Norris, RH; Cruz-Inigo, AE; Davis, DM; Davis, MD; Sandroni, P; Tollefson, MM, 2012) |
| "Lidocaine treatment attenuated these changes." | 1.31 | Lidocaine attenuates acute lung injury induced by a combination of phospholipase A2 and trypsin. ( Kiyonari, Y; Maekawa, N; Mikawa, K; Nishina, K; Obara, H, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 6 (54.55) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Letson, HL | 1 |
| Dobson, GP | 1 |
| Xia, W | 1 |
| Wang, L | 1 |
| Yu, D | 1 |
| Mu, X | 1 |
| Zhou, X | 1 |
| Sandhofer, M | 2 |
| Hanke, CW | 1 |
| Habbema, L | 1 |
| Podda, M | 1 |
| Rapprich, S | 1 |
| Schmeller, W | 1 |
| Herbst, K | 1 |
| Anderhuber, F | 1 |
| Pilsl, U | 1 |
| Sattler, G | 1 |
| Moosbauer, W | 1 |
| Sattler, S | 1 |
| Schauer, P | 1 |
| Faulhaber, J | 1 |
| Maier, S | 1 |
| Barsch, M | 1 |
| Mindt, S | 1 |
| Halk, AB | 1 |
| Cook-Norris, RH | 1 |
| Tollefson, MM | 1 |
| Cruz-Inigo, AE | 1 |
| Sandroni, P | 1 |
| Davis, MD | 1 |
| Davis, DM | 1 |
| Mori, K | 1 |
| Ito, H | 1 |
| Toda, Y | 1 |
| Hashimoto, T | 1 |
| Miyazaki, M | 1 |
| Saijo, T | 1 |
| Kuroda, Y | 1 |
| Addario, L | 1 |
| Scaglione, G | 1 |
| Tritto, G | 1 |
| Di Costanzo, GG | 1 |
| De Luca, M | 1 |
| Lampasi, F | 1 |
| Galeota Lanza, A | 1 |
| Picciotto, FP | 1 |
| Tartaglione, MT | 1 |
| Utech, W | 1 |
| Macr, M | 1 |
| Giannelli, E | 1 |
| Ascione, A | 1 |
| Kanzler, S | 1 |
| Teufel, A | 1 |
| Galle, PR | 1 |
| Stahl, M | 1 |
| Meyer, C | 1 |
| Haas, E | 1 |
| Glaenz, T | 1 |
| Zutt, M | 1 |
| Gottehrer, NR | 1 |
| Giannini, E | 1 |
| Botta, F | 1 |
| Fasoli, A | 1 |
| Ceppa, P | 1 |
| Risso, D | 1 |
| Lantieri, PB | 1 |
| Celle, G | 1 |
| Testa, R | 1 |
| Kiyonari, Y | 1 |
| Nishina, K | 1 |
| Mikawa, K | 1 |
| Maekawa, N | 1 |
| Obara, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Double-blind Randomized Clinical Trial to Evaluate the Reduction of Pain in the Wounds Treatment Previously Applying Lidocaine Topical Solution vs Placebo, in the Outpatients Area.[NCT03676556] | Phase 3 | 46 participants (Anticipated) | Interventional | 2021-06-16 | Recruiting | ||
| Randomised, Double-blind Clinical Trial to Evaluate the Reduction of Pain in the Wounds Treatment Previously Applying Lidocaine Topical Solution vs Placebo[NCT02584335] | Phase 4 | 7 participants (Actual) | Interventional | 2015-07-31 | Terminated (stopped due to Difficulties with the recruitment) | ||
| A Single Center, Randomized, Double-Blind Controlled Study of Topical Endoluminal Pancreatic Duct Lidocaine for Prevention of Post-ERCP Pancreatitis[NCT00953199] | 506 participants (Actual) | Interventional | 2010-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The primary outcome of interest will be development of acute pancreatitis defined as new or worsening abdominal pain post-ERCP associated with an increase in serum amylase at least 3 times the upper limit of normal. (NCT00953199)
Timeframe: 24-48 hours post-procedure
| Intervention | participants (Number) |
|---|---|
| Lidocaine | 26 |
| Normal Saline | 20 |
serum amylase levels are measure by a blood draw (NCT00953199)
Timeframe: measurement is taken 2 hrs after ERCP
| Intervention | units/liter (Mean) |
|---|---|
| Lidocaine | 130 |
| Normal Saline | 128 |
1 review available for lidocaine and Disease Exacerbation
| Article | Year |
|---|---|
[Liver function test to predict hepatic failure after liver resection--expensive and without clinical relevance?].
Topics: Bilirubin; Disease Progression; Hepatectomy; Humans; Indocyanine Green; Lidocaine; Liver; Liver Cirr | 2007 |
10 other studies available for lidocaine and Disease Exacerbation
| Article | Year |
|---|---|
Adenosine, lidocaine, and Mg2+ (ALM) resuscitation fluid protects against experimental traumatic brain injury.
Topics: Adenosine; Animals; Brain Injuries, Traumatic; Disease Models, Animal; Disease Progression; Fluid Th | 2018 |
Lidocaine inhibits the progression of retinoblastoma in vitro and in vivo by modulating the miR‑520a‑3p/EGFR axis.
Topics: Apoptosis; Base Sequence; Cell Line, Tumor; Cell Proliferation; Child; Child, Preschool; Disease Pro | 2019 |
Prevention of Progression of Lipedema With Liposuction Using Tumescent Local Anesthesia: Results of an International Consensus Conference.
Topics: Anesthesia, Local; Anesthetics, Local; Consensus Development Conferences as Topic; Disease Progressi | 2020 |
Pediatric erythromelalgia: a retrospective review of 32 cases evaluated at Mayo Clinic over a 37-year period.
Topics: Adolescent; Anesthetics, Local; Cellulitis; Child; Child, Preschool; Comorbidity; Disease Progressio | 2012 |
Successful management of intractable epilepsy with lidocaine tapes and continuous subcutaneous lidocaine infusion.
Topics: Administration, Cutaneous; Anticonvulsants; Child; Child, Preschool; Disease Progression; Drug Admin | 2004 |
Prognostic value of quantitative liver function tests in viral cirrhosis: a prospective study.
Topics: Adult; Disease Progression; Epidemiologic Methods; Female; Galactose; Hepatitis, Viral, Human; Human | 2006 |
Leg ulcer progression caused by topical anesthesia with EMLA cream.
Topics: Anesthetics, Local; Debridement; Diagnosis, Differential; Disease Progression; Drug Eruptions; Femal | 2008 |
Leg ulcer progression caused by topical anesthesia with EMLA cream.
Topics: Anesthetics, Local; Debridement; Diagnosis, Differential; Disease Progression; Drug Eruptions; Femal | 2008 |
Leg ulcer progression caused by topical anesthesia with EMLA cream.
Topics: Anesthetics, Local; Debridement; Diagnosis, Differential; Disease Progression; Drug Eruptions; Femal | 2008 |
Leg ulcer progression caused by topical anesthesia with EMLA cream.
Topics: Anesthetics, Local; Debridement; Diagnosis, Differential; Disease Progression; Drug Eruptions; Femal | 2008 |
Antimicrobials in periodontics: controlling chronic disease.
Topics: Anesthetics, Combined; Anesthetics, Local; Anti-Bacterial Agents; Bacteroidaceae Infections; Bactero | 2008 |
Progressive liver functional impairment is associated with an increase in AST/ALT ratio.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Chronic Disease; Clinical Enzyme Tests; Di | 1999 |
Lidocaine attenuates acute lung injury induced by a combination of phospholipase A2 and trypsin.
Topics: Animals; Blood Gas Analysis; Disease Models, Animal; Disease Progression; Drug Evaluation, Preclinic | 2000 |