lidocaine has been researched along with Diabetes Mellitus, Type 2 in 13 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the variations in blood glucose levels, hemodynamic effects and patient anxiety scores during tooth extraction in patients with type 2 diabetes mellitus T2DM and coronary disease under local anesthesia with 2% lidocaine with or without epinephrine." | 5.20 | Local anesthesia with epinephrine is safe and effective for oral surgery in patients with type 2 diabetes mellitus and coronary disease: a prospective randomized study. ( Neves, IL; Neves, RS; Ramires, JA; Santos-Paul, MA, 2015) |
| "Nisoldipine (N) is a dihydropyridine calcium antagonist marketed as a racemic mixture and used for the treatment of hypertension." | 5.10 | Dynamic and kinetic disposition of nisoldipine enantiomers in hypertensive patients presenting with type-2 diabetes mellitus. ( Coelho, EB; Dos Santos, NA; Geleilete, TJ; Lanchote, VL; Marques, MP, 2002) |
| " Postoperative safety included adverse events, endothelial cell density and vision." | 2.94 | Safety and efficacy of a standardized intracameral combination of mydriatics and anesthetic for cataract surgery in type-2 diabetic patients. ( Behndig, A; Bérard, A; Chiambaretta, F; Cochener-Lamard, B; Güell, JL; Labetoulle, M; Mencucci, R; Nuijts, R; Pleyer, U; Rosen, P; Szaflik, J; Tassignon, MJ, 2020) |
| "Chronic pain is now viewed as a biopsychosocial phenomenon, in which biological, psychological, and social factors are at work." | 2.44 | Practical management strategies for the chronic pain patient. ( Forde, G; Stanos, S, 2007) |
| "The research included 40 patients with type 2 diabetes with indications of tooth extraction." | 1.72 | The changes in levels of blood cortisol, glucose, and oxygen saturation in type 2 diabetic patients during tooth extraction. ( Ademi Abdyli, R; Agani, Z; Ahmedi, J; Hamiti-Krasniqi, V; Prekazi Loxha, M; Rexhepi, A; Stubljar, D, 2022) |
| "In the patients with NIDDM, who had a similar level of glycosylated haemoglobin, while there was no significant difference in the binding of lidocaine there was a significant increase in warfarin binding compared with the control population (99." | 1.29 | Plasma protein binding of lidocaine and warfarin in insulin-dependent and non-insulin-dependent diabetes mellitus. ( Barry, MG; Collins, WC; Cullen, MJ; Feely, J; O'Byrne, S; O'Connor, P, 1993) |
| "kg-1) associated with a decreased elimination half-life and mean residence time." | 1.28 | Altered pharmacokinetics of lignocaine after epidural injection in type II diabetics. ( Adithan, C; Peeyush, M; Ravishankar, M; Shashindran, CH, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 6 (46.15) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Agani, Z | 1 |
| Ahmedi, J | 1 |
| Ademi Abdyli, R | 1 |
| Prekazi Loxha, M | 1 |
| Hamiti-Krasniqi, V | 1 |
| Rexhepi, A | 1 |
| Stubljar, D | 1 |
| Labetoulle, M | 1 |
| Behndig, A | 1 |
| Tassignon, MJ | 1 |
| Nuijts, R | 1 |
| Mencucci, R | 1 |
| Güell, JL | 1 |
| Pleyer, U | 1 |
| Szaflik, J | 1 |
| Rosen, P | 1 |
| Bérard, A | 1 |
| Chiambaretta, F | 1 |
| Cochener-Lamard, B | 1 |
| Santos-Paul, MA | 1 |
| Neves, IL | 1 |
| Neves, RS | 1 |
| Ramires, JA | 1 |
| Luo, G | 1 |
| He, J | 1 |
| Wu, T | 1 |
| Huang, Y | 1 |
| Miao, Z | 1 |
| Zhao, Z | 1 |
| Wang, X | 1 |
| Wang, Y | 1 |
| Milic, MS | 1 |
| Brkovic, B | 1 |
| Krsljak, E | 1 |
| Stojic, D | 1 |
| Ochoa, N | 1 |
| Gogola, GR | 1 |
| Gorniak, SL | 1 |
| Forde, G | 1 |
| Stanos, S | 1 |
| Strom, NA | 1 |
| Sawyer, JR | 1 |
| Roberts, SK | 1 |
| Kingsley-Berg, SM | 1 |
| Charkoudian, N | 1 |
| Wells, JH | 1 |
| Hurvitz, KA | 1 |
| Marques, MP | 1 |
| Coelho, EB | 1 |
| Dos Santos, NA | 1 |
| Geleilete, TJ | 1 |
| Lanchote, VL | 1 |
| Tily, FE | 1 |
| Thomas, S | 1 |
| O'Byrne, S | 1 |
| Barry, MG | 1 |
| Collins, WC | 1 |
| O'Connor, P | 1 |
| Cullen, MJ | 1 |
| Feely, J | 1 |
| Peeyush, M | 1 |
| Ravishankar, M | 1 |
| Adithan, C | 1 |
| Shashindran, CH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy of the Intracamerally Administered Mydriatics for Cataract Surgery in Patients With Primary Open-angle Glaucoma.[NCT05925894] | 60 participants (Actual) | Interventional | 2021-03-18 | Completed | |||
| Efficacy and Safety Assessment of Intracameral Injection of T2380 in Cataract Surgery Versus Reference Group (Topical Mydriatics and Anaesthetic)[NCT02101359] | Phase 3 | 609 participants (Actual) | Interventional | 2011-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT02101359)
Timeframe: Day 0
| Intervention | percentage of responders (Number) |
|---|---|
| T2380 | 98.9 |
| Reference Group | 94.7 |
1 review available for lidocaine and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Practical management strategies for the chronic pain patient.
Topics: Administration, Cutaneous; Amines; Analgesics; Antidepressive Agents, Tricyclic; Carbamazepine; Chro | 2007 |
5 trials available for lidocaine and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Safety and efficacy of a standardized intracameral combination of mydriatics and anesthetic for cataract surgery in type-2 diabetic patients.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anterior Chamber; Cataract; Diabetes Mellitus, T | 2020 |
Safety and efficacy of a standardized intracameral combination of mydriatics and anesthetic for cataract surgery in type-2 diabetic patients.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anterior Chamber; Cataract; Diabetes Mellitus, T | 2020 |
Safety and efficacy of a standardized intracameral combination of mydriatics and anesthetic for cataract surgery in type-2 diabetic patients.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anterior Chamber; Cataract; Diabetes Mellitus, T | 2020 |
Safety and efficacy of a standardized intracameral combination of mydriatics and anesthetic for cataract surgery in type-2 diabetic patients.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anterior Chamber; Cataract; Diabetes Mellitus, T | 2020 |
Local anesthesia with epinephrine is safe and effective for oral surgery in patients with type 2 diabetes mellitus and coronary disease: a prospective randomized study.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Anxiety; Blood Glucose; Blood | 2015 |
Comparison of pulpal anesthesia and cardiovascular parameters with lidocaine with epinephrine and lidocaine with clonidine after maxillary infiltration in type 2 diabetic volunteers.
Topics: Adult; Analgesics; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Clonidine; Cross-Over | 2016 |
Dynamic and kinetic disposition of nisoldipine enantiomers in hypertensive patients presenting with type-2 diabetes mellitus.
Topics: Adult; Antihypertensive Agents; Area Under Curve; Biomarkers; Blood Glucose; Blood Pressure; Cross-O | 2002 |
Glycemic effect of administration of epinephrine-containing local anaesthesia in patients undergoing dental extraction, a comparison between healthy and diabetic patients.
Topics: Adolescent; Adult; Anesthetics, Local; Blood Glucose; Diabetes Mellitus, Type 2; Epinephrine; Female | 2007 |
7 other studies available for lidocaine and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
The changes in levels of blood cortisol, glucose, and oxygen saturation in type 2 diabetic patients during tooth extraction.
Topics: Anesthetics, Local; Diabetes Mellitus, Type 2; Epinephrine; Glucose; Humans; Hydrocortisone; Lidocai | 2022 |
The Therapeutic Effect of Stellate Ganglion Block on Facial Nerve Palsy in Patients with Type 2 Diabetes Mellitus.
Topics: Adult; Anesthetics, Local; Antipyrine; Aspirin; Autonomic Nerve Block; Blood Glucose; Dexamethasone; | 2015 |
Contribution of tactile dysfunction to manual motor dysfunction in type II diabetes.
Topics: Aged; Analysis of Variance; Anesthetics, Local; Case-Control Studies; Diabetes Mellitus, Type 2; Fem | 2016 |
Local sensory nerve control of skin blood flow during local warming in type 2 diabetes mellitus.
Topics: Adult; Aged; Anesthetics, Local; Blood Glucose; Diabetes Mellitus, Type 2; Electrocardiography; Fema | 2010 |
An evidence-based approach to liposuction.
Topics: Adult; Anesthetics, Local; Comorbidity; Diabetes Mellitus, Type 2; Evidence-Based Medicine; Female; | 2011 |
Plasma protein binding of lidocaine and warfarin in insulin-dependent and non-insulin-dependent diabetes mellitus.
Topics: Adolescent; Adult; Aged; Blood Proteins; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Dialy | 1993 |
Altered pharmacokinetics of lignocaine after epidural injection in type II diabetics.
Topics: Adult; Aged; Anesthesia, Epidural; Blood Glucose; Chromatography, High Pressure Liquid; Diabetes Mel | 1992 |