lidocaine has been researched along with Developmental Psychomotor Disorders in 6 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ochoa, N | 1 |
| Gogola, GR | 1 |
| Gorniak, SL | 1 |
| Boylan, GB | 1 |
| Rennie, JM | 1 |
| Chorley, G | 1 |
| Pressler, RM | 1 |
| Fox, GF | 1 |
| Farrer, K | 1 |
| Morton, M | 1 |
| Binnie, CD | 1 |
| Katsuta, T | 1 |
| Morioka, T | 1 |
| Hasuo, K | 1 |
| Miyahara, S | 1 |
| Fukui, M | 1 |
| Masuda, K | 1 |
| Selcuk, E | 1 |
| Ertürk, S | 1 |
| Afrashi, A | 1 |
| Lieb, L | 1 |
| Korttila, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Antipruritic Effect of Topical Ketamine, Amitriptyline, and Lidocaine[NCT03096444] | Phase 2 | 13 participants (Actual) | Interventional | 2017-05-23 | Terminated (stopped due to Efficacy was not seen after interim analysis) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Peak itch intensity between the vehicle and 4 other active treatments (individual ketamine, amitriptyline, or lidocaine, and KeAmLi-combo). Itch intensity was measured on a 100mm scale visual analog scale for 10 minutes. 0 was weighted with no itch and 100 was weighted with most itch imaginable." (NCT03096444)
Timeframe: 10 minutes
| Intervention | Intensity score (Mean) |
|---|---|
| Topical KeAmLi Combo | 62.7 |
| Topical Ketamine | 63.1 |
| Topical Amitriptyline | 69.2 |
| Topical Lidocaine | 65.8 |
| Topical Vehicle | 61.9 |
Assess mechanical detection and pain thresholds using von Frey filaments stimulators (measured in force mN) to calculate the final threshold as the geometric mean of five series of ascending and descending stimuli. (NCT03096444)
Timeframe: 5 minutes
| Intervention | mN (Mean) | |
|---|---|---|
| Mechanical Detection Threshold | Mechanical Pain Threshold | |
| Topical Amitriptyline | 3.573423965 | 152.4768146 |
| Topical KeAmLi Combo | 3.519376956 | 152.3293608 |
| Topical Ketamine | 3.464204768 | 135.9 |
| Topical Lidocaine | 3.546037659 | 126.9 |
| Topical Vehicle | 3.525692637 | 148.7138273 |
Two standardized quantitative sensory tests are performed to measure warmth detection threshold (assesses the threshold of which warmth sensation is first detected) and heat pain threshold (assesses the threshold at which heat pain sensation is first detected). Measured in change in celsius. (NCT03096444)
Timeframe: 3 minutes
| Intervention | Degrees celsius (Mean) | |
|---|---|---|
| Warm Detection Threshold | Heat Pain Threshold | |
| Topical Amitriptyline | 33.9 | 40.0 |
| Topical KeAmLi Combo | 33.6 | 39.8 |
| Topical Ketamine | 34.0 | 40.0 |
| Topical Lidocaine | 33.7 | 39.4 |
| Topical Vehicle | 33.8 | 39.7 |
1 review available for lidocaine and Developmental Psychomotor Disorders
| Article | Year |
|---|---|
An adverse reaction to local anaesthesia: report of a case.
Topics: Adult; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Diagnostic Errors; Drug Hypersensi | 1996 |
2 trials available for lidocaine and Developmental Psychomotor Disorders
| Article | Year |
|---|---|
Second-line anticonvulsant treatment of neonatal seizures: a video-EEG monitoring study.
Topics: Anticonvulsants; Clonazepam; Drug Resistance; Electroencephalography; Epilepsy; Female; Humans; Infa | 2004 |
Psychomotor skills related to driving after intramuscular lidocaine.
Topics: Adolescent; Adult; Attention; Automobile Driving; Clinical Trials as Topic; Drug Combinations; Epine | 1974 |
3 other studies available for lidocaine and Developmental Psychomotor Disorders
| Article | Year |
|---|---|
Contribution of tactile dysfunction to manual motor dysfunction in type II diabetes.
Topics: Aged; Analysis of Variance; Anesthetics, Local; Case-Control Studies; Diabetes Mellitus, Type 2; Fem | 2016 |
Discrepancy between provocative test and clinical results following endovascular obliteration of spinal arteriovenous malformation.
Topics: Adult; Arteries; Arteriovenous Malformations; Embolization, Therapeutic; Evoked Potentials, Somatose | 1993 |
[Psychophysical performance deficit after outpatient anesthesis and necessary care].
Topics: Activities of Daily Living; Ambulatory Care; Analgesics, Opioid; Anesthesia, Local; Atropine; Barbit | 1976 |