lidocaine has been researched along with Dermatoses in 41 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report two cases of refractory chronic graft-versus-host disease after donor lymphocyte infusions in which the skin lesions improved dramatically with the use of intravenous pulses of lidocaine." | 7.71 | Beneficial effect of intravenous lidocaine in cutaneous chronic graft-versus-host disease secondary to donor lymphocyte infusion. ( Ahmed, H; Ball, ED; Bashey, A; Carrier, E; Coutinho, M; Holman, P; Paton, EJ; Simoes, BP; Stracieri, AB; Voltarelli, JC, 2001) |
| " Additionally, hemodialysis patients exhibit reduced barrier function and can experience pain associated with repeated needle insertion; the repeated use of lidocaine tape to manage the pain can cause further skin damage." | 5.12 | Onset Mechanism and Pharmaceutical Management of Dry Skin. ( Ooi, K, 2021) |
| " We discuss the literature that has influenced current office behavior regarding endocarditis prophylaxis, the use of electrosurgery with pacemakers, arrhythmogenic drug interactions, vasovagal syncope, lidocaine "allergy," and bleeding complications from oral anticoagulants." | 4.79 | Medical issues and emergencies in the dermatology office. ( Fader, DJ; Johnson, TM, 1997) |
| "We report two cases of refractory chronic graft-versus-host disease after donor lymphocyte infusions in which the skin lesions improved dramatically with the use of intravenous pulses of lidocaine." | 3.71 | Beneficial effect of intravenous lidocaine in cutaneous chronic graft-versus-host disease secondary to donor lymphocyte infusion. ( Ahmed, H; Ball, ED; Bashey, A; Carrier, E; Coutinho, M; Holman, P; Paton, EJ; Simoes, BP; Stracieri, AB; Voltarelli, JC, 2001) |
| "Using an percutaneous anesthetic Lidocaine ointment (EMLA cream 5%), we treated patients with mollusca contagiosa, condylomata acuminata, and verrucae plantaris by superficial curettage or electrocaustic surgery." | 3.67 | [Experiences with percutaneous anesthesia using a lidocaine-prilocaine cream (EMLA 5% cream)]. ( Mensing, H; Wagner, G, 1989) |
| "Potassium chloride (KCl) given subcutaneously in high concentrations causes necrosis of skin, possibly from vasoconstriction around the injection site." | 3.65 | Lidocaine treatment of experimental cutaneous lesions from potassium chloride injection. ( Behnia, R; Wilkinson, CJ, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (29.27) | 18.7374 |
| 1990's | 13 (31.71) | 18.2507 |
| 2000's | 11 (26.83) | 29.6817 |
| 2010's | 4 (9.76) | 24.3611 |
| 2020's | 1 (2.44) | 2.80 |
| Authors | Studies |
|---|---|
| Ooi, K | 1 |
| Kim, HO | 1 |
| Kim, BG | 1 |
| Shin, JW | 1 |
| Huh, SY | 1 |
| Youn, SW | 1 |
| Huh, CH | 1 |
| Park, KC | 1 |
| Bruce, AM | 1 |
| Spencer, JM | 1 |
| Gleeson, C | 1 |
| Hussain, W | 1 |
| Spreadborough, J | 1 |
| Mortimer, N | 1 |
| Salmon, P | 1 |
| Baumgartner, J | 1 |
| Cracowski, JL | 1 |
| Gaillard-Bigot, F | 1 |
| Cracowski, C | 1 |
| Sors, C | 1 |
| Roustit, M | 1 |
| Millet, C | 1 |
| Kinoshita, T | 1 |
| Shibaji, T | 1 |
| Umino, M | 1 |
| FARBER, EM | 1 |
| ROTH, RJ | 1 |
| ASCHHEIM, E | 1 |
| EDDY, DD | 1 |
| EPINETTE, WW | 1 |
| CARPENTER, CL | 1 |
| JOLLY, HW | 1 |
| REED, RJ | 1 |
| Lee, DP | 1 |
| Chang, SE | 1 |
| Schecter, AK | 1 |
| Pariser, DM | 1 |
| Pariser, RJ | 1 |
| Ling, MR | 1 |
| Stewart, D | 1 |
| Sadick, NS | 1 |
| Sajeev, CG | 1 |
| Francis, J | 1 |
| Sankar, V | 1 |
| Vasudev, B | 1 |
| Venugopal, K | 1 |
| Meeuse, JJ | 1 |
| Reyners, AK | 1 |
| Wymenga, AN | 1 |
| Cazes, A | 1 |
| Prost-Squarcioni, C | 1 |
| Bodemer, C | 1 |
| Heller, M | 1 |
| Brousse, N | 1 |
| Fraitag, S | 1 |
| Regan, BM | 1 |
| Galysh, FT | 1 |
| Morris, RN | 1 |
| Scheepers, JH | 1 |
| Quaba, AA | 1 |
| Dire, DJ | 1 |
| Hogan, DE | 1 |
| Davis, A | 1 |
| Krafchik, BR | 1 |
| Bassøe, CF | 1 |
| Olivencia, JA | 1 |
| Gupta, AK | 1 |
| Sibbald, RG | 1 |
| Fader, DJ | 1 |
| Johnson, TM | 1 |
| Pay, AD | 1 |
| Kenealy, J | 1 |
| Downs, AM | 1 |
| Lear, JT | 1 |
| Wallington, TB | 1 |
| Sansom, JE | 1 |
| Cunningham, BB | 2 |
| Grognard, C | 1 |
| Clarkson, A | 1 |
| Choonara, I | 1 |
| O'Donnell, K | 1 |
| Wormser, U | 1 |
| Sintov, A | 1 |
| Brodsky, B | 1 |
| Nyska, A | 1 |
| Breuninger, H | 1 |
| Nogova, L | 1 |
| Hobbach, PS | 1 |
| Schimek, F | 1 |
| Voltarelli, JC | 1 |
| Ahmed, H | 1 |
| Paton, EJ | 1 |
| Stracieri, AB | 1 |
| Holman, P | 1 |
| Bashey, A | 1 |
| Coutinho, M | 1 |
| Simoes, BP | 1 |
| Ball, ED | 1 |
| Carrier, E | 1 |
| Chen, BK | 1 |
| Chvapil, M | 1 |
| Hameroff, SR | 1 |
| O'Dea, K | 1 |
| Peacock, EE | 1 |
| Behnia, R | 1 |
| Wilkinson, CJ | 1 |
| Abadir, A | 1 |
| Maloney, JM | 1 |
| Bezzant, JL | 1 |
| Stephen, RL | 1 |
| Petelenz, TJ | 1 |
| Wagner, G | 1 |
| Mensing, H | 1 |
| Fitzgerald, M | 1 |
| Millard, C | 1 |
| McIntosh, N | 1 |
| Venkei, T | 1 |
| Bozóky, L | 1 |
| Bonnet, J | 1 |
| Calas, E | 1 |
| Florens, A | 1 |
| Campbell, AH | 1 |
| Stasse, JA | 1 |
| Lord, GH | 1 |
| Willson, JE | 1 |
| Lynas, RF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Efficacy of the Eutectic Mixture of Local Anesthetics (EMLA) Cream Versus the Synera Patch for Pain Reduction During Venipuncture in Children[NCT00530803] | Phase 2 | 100 participants (Actual) | Interventional | 2007-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The NRS (Numerical Rating Scale) is a 6-point rating scale where 0= no pain and 5 = worst pain. Blinded observers reported their own subjective evaluation of the level of pain experienced by the participants at tourniquet placement. Total number of participants subjectively evaluated as experiencing each pain level is reported. (NCT00530803)
Timeframe: before venipuncture
| Intervention | Participants (Count of Participants) | |||||
|---|---|---|---|---|---|---|
| Participants evaluated at NRS = 0 (No pain) | Participants evaluated at NRS = 1 | Participants evaluated at NRS = 2 | Participants evaluated at NRS = 3 | Participants evaluated at NRS = 4 | Participants evaluated at NRS = 5 | |
| EMLA Cream | 41 | 6 | 2 | 1 | 0 | 0 |
| Synera Patch | 37 | 6 | 5 | 1 | 1 | 0 |
The NRS (Numerical Rating Scale) is a 6-point rating scale where 0= no pain and 5 = worst pain. Blinded observers reported their own subjective evaluation of the level of pain participants were experiencing 5 minutes after the venipuncture was completed. Total number of participants subjectively evaluated as experiencing each pain level is reported. (NCT00530803)
Timeframe: 5 minutes post venipuncture
| Intervention | Participants (Count of Participants) | |||||
|---|---|---|---|---|---|---|
| Participants evaluated at NRS = 0 (No pain) | Participants evaluated at NRS = 1 | Participants evaluated at NRS = 2 | Participants evaluated at NRS = 3 | Participants evaluated at NRS = 4 | Participants evaluated at NRS = 5 | |
| EMLA Cream | 45 | 3 | 1 | 1 | 0 | 0 |
| Synera Patch | 45 | 4 | 1 | 0 | 0 | 0 |
The NRS (Numerical Rating Scale) is a 6-point rating scale where 0= no pain and 5 = worst pain. Blinded observers reported their own subjective evaluation of the level of pain experienced by the participants at needle insertion. Total number of participants subjectively evaluated as experiencing each pain level is reported. (NCT00530803)
Timeframe: during needle insertion
| Intervention | Participants (Count of Participants) | |||||
|---|---|---|---|---|---|---|
| Participants evaluated at NRS = 0 (No pain) | Participants evaluated at NRS = 1 | Participants evaluated at NRS = 2 | Participants evaluated at NRS = 3 | Participants evaluated at NRS = 4 | Participants evaluated at NRS = 5 | |
| EMLA Cream | 32 | 14 | 2 | 2 | 0 | 0 |
| Synera Patch | 25 | 12 | 9 | 2 | 2 | 0 |
The Numerical Rating Scale (NRS) is a 6-point rating scale where 0= no pain and 5 = worst pain. Parents reported their own subjective evaluation of participants pain level. Each participant had only one parental assessment. Total number of parental assessment for each pain level on the 6-point NRS is reported as total number of participants experiencing that pain level. (NCT00530803)
Timeframe: immediately after venipuncture is completed
| Intervention | Participants (Count of Participants) | |||||
|---|---|---|---|---|---|---|
| number of participants with NRS=0 (no pain) | number of participants with NRS=1 | number of participants with NRS=2 | number of participants with NRS=3 | number of participants with NRS=4 | number of participants with NRS=5 | |
| EMLA Cream | 42 | 6 | 1 | 1 | 0 | 0 |
| Synera Patch | 41 | 5 | 1 | 2 | 0 | 1 |
"Participants were asked to report their level of pain using a 6-point Wong-Baker FACES Pain Rating Scale ranging from 0, no pain, to 5, the most pain you can have. The Wong-Baker FACES Pain Rating Scale is a validated tool for measuring pain in patients as young as 3 years old. A FACES pain score less than or equal to 2 is considered no pain to mild pain, and is clinically acceptable. Studies have shown average FACES pain scores for children receiving vascular access with placebo to be 2.2 to 3.5." (NCT00530803)
Timeframe: immediately after completion of venipuncture
| Intervention | Participants (Count of Participants) | |||||
|---|---|---|---|---|---|---|
| Participants with FACES Score = 0 (No pain) | Participants with FACES Score = 1 | Participants with FACES Score = 2 | Participants with FACES Score = 3 | Participants with FACES Score = 4 | Participants with FACES Score = 5 | |
| EMLA Cream | 42 | 6 | 2 | 0 | 0 | 0 |
| Synera Patch | 38 | 8 | 3 | 1 | 0 | 0 |
7 reviews available for lidocaine and Dermatoses
| Article | Year |
|---|---|
Onset Mechanism and Pharmaceutical Management of Dry Skin.
Topics: Age Factors; Animals; Deficiency Diseases; Dermatologic Agents; Dietary Supplements; Eczema; Female; | 2021 |
New drugs in pediatric dermatology.
Topics: Acyclovir; Anesthetics, Local; Calcitriol; Child; Cyclosporine; Dermatologic Agents; Drug Combinatio | 1993 |
Ambulatory phlebectomy. A rare complication of local anesthetic: case report and literature review.
Topics: Adult; Ambulatory Surgical Procedures; Anesthetics, Local; Epinephrine; Female; Humans; Lidocaine; N | 1996 |
Medical issues and emergencies in the dermatology office.
Topics: Anaphylaxis; Anesthetics, Local; Anti-Arrhythmia Agents; Anticoagulants; Cerebrovascular Disorders; | 1997 |
Laser therapy and dermatologic surgery.
Topics: Anesthetics, Combined; Anesthetics, Local; Child; Child, Preschool; Humans; Infant; Laser Therapy; L | 1998 |
[Local anesthesia in dermatology].
Topics: Anesthesia, Local; Anesthetics, Local; Biopsy; Contraindications; Dermatology; Humans; Lidocaine; Li | 1999 |
Topical anesthetics in children: agents and techniques that equally comfort patients, parents, and clinicians.
Topics: Administration, Topical; Anesthetics, Local; Child; Drug Combinations; Humans; Iontophoresis; Lidoca | 2001 |
6 trials available for lidocaine and Dermatoses
| Article | Year |
|---|---|
Change of skin color after application of topical anesthetic cream.
Topics: Adult; Anesthetics, Local; Case-Control Studies; Drug Combinations; Emollients; Humans; Laser Therap | 2009 |
Involvement of cytochrome epoxygenase metabolites in cutaneous postocclusive hyperemia in humans.
Topics: 8,11,14-Eicosatrienoic Acid; Adult; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; Female; | 2013 |
Randomized, double-blind, placebo-controlled study evaluating the lidocaine/tetracaine patch for induction of local anesthesia prior to minor dermatologic procedures in geriatric patients.
Topics: Aged; Anesthetics, Local; Biopsy; Cryotherapy; Double-Blind Method; Drug Combinations; Female; Human | 2005 |
Double-blinded comparison of diphenhydramine versus lidocaine as a local anesthetic.
Topics: Adult; Anesthetics, Local; Diphenhydramine; Double-Blind Method; Drug Hypersensitivity; Humans; Inje | 1993 |
Eutectic lidocaine/prilocaine 5% cream and patch may provide satisfactory analgesia for excisional biopsy or curettage with electrosurgery of cutaneous lesions. A randomized, controlled, parallel group study.
Topics: Adhesiveness; Adult; Aged; Aged, 80 and over; Analgesia; Anesthetics, Local; Biopsy; Curettage; Drug | 1996 |
Cutaneous hypersensitivity following peripheral tissue damage in newborn infants and its reversal with topical anaesthesia.
Topics: Anesthetics, Local; Ankle Injuries; Blood Specimen Collection; Double-Blind Method; Drug Combination | 1989 |
28 other studies available for lidocaine and Dermatoses
| Article | Year |
|---|---|
Surgical myths in dermatology.
Topics: Adult; Clinical Trials as Topic; Dermatology; Drug Interactions; Ear; Epinephrine; Evidence-Based Me | 2010 |
Local anaesthetic preparation in dermatological surgery: a labour- and time-efficient approach.
Topics: Anesthesia, Local; Anesthetics, Local; Anti-Bacterial Agents; Drug Combinations; Drug Compounding; E | 2011 |
Erbium: yttrium-aluminium-garnet (Er:YAG) laser treatment of penile pearly papules.
Topics: Adult; Anesthetics, Local; Humans; Lasers, Solid-State; Lidocaine; Male; Middle Aged; Penile Disease | 2012 |
Transdermal delivery of lidocaine in vitro by alternating current.
Topics: Administration, Cutaneous; Anesthetics, Local; Animals; Electricity; In Vitro Techniques; Iontophore | 2003 |
ROLE OF TRAUMA IN ISOMORPHIC RESPONSE IN PSORIASIS.
Topics: Biomedical Research; Chymotrypsin; Humans; Hyaluronoglucosaminidase; Hypothermia; Hypothermia, Induc | 1965 |
DERMOJET HISTOPATHOLOGICAL ARTIFACTS.
Topics: Anesthesia; Anesthesia, Local; Artifacts; Biopsy; Drug Therapy; Histology; Humans; Infant; Injection | 1965 |
Subcutaneous nodules showing fat necrosis owing to mesotherapy.
Topics: Abdomen; Adult; Diagnosis, Differential; Fat Necrosis; Female; Glucose; Humans; Injections, Subcutan | 2005 |
Images in cardiovascular medicine. Ventricular tachycardia: the spectrum continues to broaden: report of Naxos disease.
Topics: Bundle-Branch Block; Cardiomyopathies; Electrocardiography; Female; Hair Diseases; Humans; Lidocaine | 2006 |
Topical lidocaine in silver sulfadiazine cream on painful, cancer, or treatment-related skin lesions.
Topics: Administration, Topical; Adult; Aged; Anesthetics, Local; Drug Combinations; Female; Humans; Lidocai | 2007 |
Histologic cutaneous modifications after the use of EMLA cream, a diagnostic pitfall: review of 13 cases.
Topics: Anesthetics, Local; Child; Child, Preschool; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combinati | 2007 |
The 2-thiopseudourea moiety, a new local anesthesiophore.
Topics: Animals; Chemistry, Organic; Cornea; Guinea Pigs; Lidocaine; Male; Mice; Organic Chemistry Phenomena | 1967 |
A two-year review of pain control during laser therapy using the flashlamp pulsed dye laser.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Anesthesia, Local; Anesthetics, Local; Child; Child, P | 1994 |
The skinache syndrome.
Topics: Aged; Anesthetics, Local; Chronic Disease; Female; Humans; Lidocaine; Male; Middle Aged; Pain Manage | 1995 |
The use of nerve blocks in the laser treatment of cutaneous lesions.
Topics: Adolescent; Adult; Aged; Anesthetics, Local; Child; Child, Preschool; Female; Humans; Laser Therapy; | 1997 |
Contact sensitivity and systemic reaction to pseudoephedrine and lignocaine.
Topics: Adult; Anesthetics, Local; Bronchodilator Agents; Dermatitis, Allergic Contact; Ephedrine; Female; H | 1998 |
Localized adverse skin reactions to topical anaesthetics.
Topics: Administration, Topical; Anesthetics, Local; Child; Humans; Lidocaine; Lidocaine, Prilocaine Drug Co | 1999 |
Topical iodine preparation as therapy against sulfur mustard-induced skin lesions.
Topics: Administration, Topical; Animals; Anti-Infective Agents, Local; Dermatologic Agents; Disease Models, | 2000 |
[Ropivacaine, an advantageous anesthetic for subcutaneous infusion anesthesia].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amides; Anesthesia, Local; Anesthetics, Local; Child; Ch | 2000 |
Beneficial effect of intravenous lidocaine in cutaneous chronic graft-versus-host disease secondary to donor lymphocyte infusion.
Topics: Adult; Bone Marrow Transplantation; Child; Chronic Disease; Female; Graft vs Host Disease; Humans; I | 2001 |
Local anesthetics and wound healing.
Topics: Anesthetics, Local; Animals; Bupivacaine; Cells, Cultured; Collagen; Fibroblasts; Glycosaminoglycans | 1979 |
Lidocaine treatment of experimental cutaneous lesions from potassium chloride injection.
Topics: Animals; Guinea Pigs; Ischemia; Lidocaine; Necrosis; Potassium Chloride; Skin; Skin Diseases; Vasoco | 1977 |
Use of local anesthetics in dermatology.
Topics: Anesthetics, Local; Bupivacaine; Dermatologic Surgical Procedures; Humans; Hypnotics and Sedatives; | 1975 |
Iontophoretic administration of lidocaine anesthesia in office practice. An appraisal.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Care; Anesthesia, Local; Animals; Cats; Child | 1992 |
[Experiences with percutaneous anesthesia using a lidocaine-prilocaine cream (EMLA 5% cream)].
Topics: Anesthetics, Local; Biopsy; Condylomata Acuminata; Drug Combinations; Electrocoagulation; Humans; Li | 1989 |
[Absorption rate of intracutaneous injected radioactive sodium in the region of precancerous and malignant tumors].
Topics: Adult; Aged; Female; Humans; Infrared Rays; Injections, Intradermal; Lidocaine; Male; Melanoma; Midd | 1973 |
[Therapeutic importance of a liquid cream with quadruple action: antalgic, antiphlogistic, antiseptic, and cicatrizant].
Topics: Benzoates; Framycetin; Humans; Hydrocortisone; Lidocaine; Polyethylenes; Skin Diseases; Vitamin A; W | 1967 |
In vivo evaluation of local anesthetics applied topically.
Topics: Animals; Benzocaine; Burns; Eye; Guinea Pigs; Lidocaine; Propylene Glycols; Rabbits; Skin Diseases | 1968 |
A suspected allergic reaction to lidocaine.
Topics: Anaphylaxis; Drug Hypersensitivity; Humans; Hypersensitivity, Delayed; Lidocaine; Male; Middle Aged; | 1969 |