lidocaine has been researched along with Dermatitis Medicamentosa in 43 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We assessed the value of tocainide in the treatment of tinnitus by performing a double-blind controlled trial in which each of 48 patients with annoying tinnitus received either tocainide HC1 900 mg/day or a placebo." | 9.05 | The value of tocainide in the treatment of tinnitus. A double-blind controlled study. ( Hulshof, JH; Vermeij, P, 1985) |
| " Minor central nervous system side effects were seen in 2 patients and dermatologic adverse reaction was seen in one patient only." | 6.66 | Efficacy and safety of oral tocainide in refractory ventricular arrhythmia: a preliminary report on an open label study. ( Mahapatra, D; Mahapatra, RK, 1986) |
| "We assessed the value of tocainide in the treatment of tinnitus by performing a double-blind controlled trial in which each of 48 patients with annoying tinnitus received either tocainide HC1 900 mg/day or a placebo." | 5.05 | The value of tocainide in the treatment of tinnitus. A double-blind controlled study. ( Hulshof, JH; Vermeij, P, 1985) |
| "A 43-year-old woman suffered from recurrent localized swellings and an eczematous dermatitis starting 1 day after an injection of lidocaine." | 3.69 | Delayed-type hypersensitivity to subcutaneous lidocaine with tolerance to articaine: confirmation by in vivo and in vitro tests. ( Bircher, AJ; Messmer, SL; Rufli, T; Surber, C, 1996) |
| " Minor central nervous system side effects were seen in 2 patients and dermatologic adverse reaction was seen in one patient only." | 2.66 | Efficacy and safety of oral tocainide in refractory ventricular arrhythmia: a preliminary report on an open label study. ( Mahapatra, D; Mahapatra, RK, 1986) |
| "Lidocaine levels were determined every 30 minutes during application and for 2 hours after removal." | 1.39 | Serum lidocaine levels and cutaneous side effects after application of 23% lidocaine 7% tetracaine ointment to the face. ( Elam, AL; Kinsley, TR; Mansalis, KA; McCleskey, PE; Patel, SM, 2013) |
| "Dibucaine reactions were most common (20/25), and lidocaine sensitization was seen in two patients." | 1.35 | Sources of sensitization, cross-reactions, and occupational sensitization to topical anaesthetics among general dermatology patients. ( Jussi, L; Lammintausta, K, 2009) |
| "Tocainide is a primary analog of lidocaine with antiarrhythmic properties used to treat ventricular rhythm disorders." | 1.27 | Tocainide: a severe adverse reaction. ( DeSimone, A; Dunn, JM; Groth, PE, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (20.93) | 18.7374 |
| 1990's | 13 (30.23) | 18.2507 |
| 2000's | 11 (25.58) | 29.6817 |
| 2010's | 10 (23.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dickison, P | 1 |
| Smith, SD | 1 |
| Voorberg, AN | 1 |
| Schuttelaar, MLA | 1 |
| Kieliszak, CR | 1 |
| Griffin, JR | 1 |
| Pollinger, TH | 1 |
| Junkins-Hopkins, JM | 1 |
| Timmermans, MW | 1 |
| Bruynzeel, DP | 1 |
| Rustemeyer, T | 1 |
| Jussi, L | 1 |
| Lammintausta, K | 1 |
| Roldán-Marín, R | 1 |
| de-la-Barreda Becerril, F | 1 |
| Mansur, AT | 1 |
| Aydingöz, IE | 1 |
| García-Vilanova-Comas, A | 1 |
| Fuster-Diana, C | 1 |
| Cubells-Parrilla, M | 1 |
| Pérez-Ferriols, MD | 1 |
| Pérez-Valles, A | 1 |
| Roig-Vila, JV | 1 |
| Vij, A | 1 |
| Markus, R | 1 |
| Stephan, F | 1 |
| Maatouk, I | 1 |
| Moutran, R | 1 |
| Obeid, G | 1 |
| Poonai, N | 1 |
| Alawi, K | 1 |
| Rieder, M | 1 |
| Lynch, T | 1 |
| Lim, R | 1 |
| Noel, J | 1 |
| Temple, A | 1 |
| Laycock, GJ | 1 |
| McCleskey, PE | 1 |
| Patel, SM | 1 |
| Mansalis, KA | 1 |
| Elam, AL | 1 |
| Kinsley, TR | 1 |
| Sobanko, JF | 1 |
| Riemersma, WA | 1 |
| Schuttelaar, ML | 1 |
| Coenraads, PJ | 1 |
| Sanchez-Morillas, L | 1 |
| Martinez, JJ | 1 |
| Martos, MR | 1 |
| Gomez-Tembleque, P | 1 |
| Andres, ER | 1 |
| Stahl, M | 1 |
| Meyer, C | 1 |
| Haas, E | 1 |
| Glaenz, T | 1 |
| Zutt, M | 1 |
| Takahama, H | 1 |
| Gómez-de la Fuente, E | 1 |
| Rosado, A | 1 |
| Alvarez, JG | 1 |
| Vicente, FJ | 1 |
| Lederman, DA | 1 |
| Freedman, PD | 1 |
| Kerpel, SM | 1 |
| Lumerman, H | 1 |
| van den Hove, J | 1 |
| Decroix, J | 1 |
| Tennstedt, D | 1 |
| Lachapelle, JM | 1 |
| Fruhstorfer, H | 1 |
| Wagener, G | 1 |
| Duggan, M | 1 |
| Burns, D | 1 |
| Henry, M | 1 |
| Mitchell, T | 1 |
| Bassett, IB | 1 |
| Delaney, TA | 1 |
| Freeman, S | 1 |
| Whalen, JD | 1 |
| Dufresne, RG | 1 |
| Bircher, AJ | 1 |
| Messmer, SL | 1 |
| Surber, C | 1 |
| Rufli, T | 1 |
| Kawada, A | 2 |
| Noguchi, H | 1 |
| Hiruma, M | 2 |
| Tajima, S | 2 |
| Ishibashi, A | 2 |
| Marshall, J | 1 |
| Gourrier, E | 1 |
| Karoubi, P | 1 |
| el Hanache, A | 1 |
| Merbouche, S | 1 |
| Mouchnino, G | 1 |
| Leraillez, J | 1 |
| Fujioka, A | 1 |
| Akiyama, M | 1 |
| Calobrisi, SD | 1 |
| Drolet, BA | 1 |
| Esterly, NB | 1 |
| Hoss, DM | 1 |
| Gross, EG | 1 |
| Grant-Kels, JM | 1 |
| Helfman, M | 1 |
| Godwin, Y | 1 |
| Brotherston, M | 1 |
| Dong, H | 1 |
| Kerl, H | 1 |
| Cerroni, L | 1 |
| Black, RJ | 1 |
| Dawson, TA | 1 |
| Strang, WC | 1 |
| Mahapatra, RK | 1 |
| Mahapatra, D | 1 |
| Bjerring, P | 1 |
| Andersen, PH | 1 |
| Arendt-Nielsen, L | 1 |
| Curley, RK | 1 |
| Baxter, PW | 1 |
| Tyldesley, WR | 1 |
| Lawrence, J | 1 |
| Arrowsmith, JB | 1 |
| Creamer, JI | 1 |
| Bosco, L | 1 |
| Dunn, JM | 1 |
| Groth, PE | 1 |
| DeSimone, A | 1 |
| Hulshof, JH | 1 |
| Vermeij, P | 1 |
| Coulter, DM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Double-blind Randomized Clinical Trial to Evaluate the Reduction of Pain in the Wounds Treatment Previously Applying Lidocaine Topical Solution vs Placebo, in the Outpatients Area.[NCT03676556] | Phase 3 | 46 participants (Anticipated) | Interventional | 2021-06-16 | Recruiting | ||
| Randomised, Double-blind Clinical Trial to Evaluate the Reduction of Pain in the Wounds Treatment Previously Applying Lidocaine Topical Solution vs Placebo[NCT02584335] | Phase 4 | 7 participants (Actual) | Interventional | 2015-07-31 | Terminated (stopped due to Difficulties with the recruitment) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 trials available for lidocaine and Dermatitis Medicamentosa
| Article | Year |
|---|---|
A comparison of amethocaine and liposomal lidocaine cream as a pain reliever before venipuncture in children: a randomized control trial.
Topics: Acute Pain; Administration, Cutaneous; Analgesics; Anesthetics, Local; Child; Child, Preschool; Doub | 2012 |
Use of EMLA cream in a department of neonatology.
Topics: Anesthetics, Local; Drug Combinations; Drug Eruptions; Drug Hypersensitivity; Hospital Departments; | 1996 |
Efficacy and safety of oral tocainide in refractory ventricular arrhythmia: a preliminary report on an open label study.
Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Central Nervous Sy | 1986 |
The value of tocainide in the treatment of tinnitus. A double-blind controlled study.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Clinical Trials as Topic; Double-Blind Method; Drug Eruptions; | 1985 |
39 other studies available for lidocaine and Dermatitis Medicamentosa
| Article | Year |
|---|---|
Biting down on the truth: A case of a delayed hypersensitivity reaction to lidocaine.
Topics: Aged; Anesthetics, Local; Drug Eruptions; Erythema; Humans; Hypersensitivity, Delayed; Lidocaine; Ma | 2019 |
A case of postoperative bullous allergic contact dermatitis caused by injection with lidocaine.
Topics: Anesthetics, Local; Dermatitis, Allergic Contact; Drug Eruptions; Female; Hand Dermatoses; Humans; I | 2019 |
Pseudo-Bullous Dermatosis Induced by Topical Anesthetic Agent-Clues to This Localized Toxic Reaction.
Topics: Biopsy; Drug Eruptions; Female; Humans; Infant; Lidocaine; Lidocaine, Prilocaine Drug Combination; P | 2017 |
Allergic contact dermatitis from EMLA cream: concomitant sensitization to both local anesthetics lidocaine and prilocaine.
Topics: Aged, 80 and over; Anesthetics, Local; Dermatitis, Allergic Contact; Drug Eruptions; Female; Humans; | 2009 |
Sources of sensitization, cross-reactions, and occupational sensitization to topical anaesthetics among general dermatology patients.
Topics: Administration, Topical; Anesthetics, Local; Dermatitis, Allergic Contact; Dermatitis, Occupational; | 2009 |
Petechial and purpuric eruption induced by lidocaine/prilocaine cream: a rare side effect.
Topics: Anesthetics, Combined; Anesthetics, Local; Child, Preschool; Drug Eruptions; Humans; Lidocaine; Lido | 2009 |
Reverse isotopic response: a rarely reported phenomenon.
Topics: Adult; Anesthetics, Local; Anti-Allergic Agents; Cetirizine; Dermatitis, Contact; Drug Eruptions; Fe | 2009 |
Nicolau syndrome after lidocaine injection and cold application: a rare complication of breast core needle biopsy.
Topics: Amoxicillin; Anesthetics, Local; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Bac | 2011 |
Immediate vesicular eruption caused by topical 23% lidocaine 7% tetracaine ointment in a patient scheduled for laser therapy: a new adverse drug reaction.
Topics: Administration, Cutaneous; Adult; Anesthetics, Local; Drug Eruptions; Facial Dermatoses; Humans; Las | 2011 |
[Facial angioedema following hyaluronic acid injection].
Topics: Angioedema; Anti-Inflammatory Agents; Dermatologic Agents; Drug Eruptions; Drug Therapy, Combination | 2012 |
A case report of anaphylaxis to chlorhexidine during urinary catheterisation.
Topics: Aged; Anaphylaxis; Anti-Infective Agents, Local; Arthroplasty, Replacement, Hip; Chlorhexidine; Drug | 2012 |
Serum lidocaine levels and cutaneous side effects after application of 23% lidocaine 7% tetracaine ointment to the face.
Topics: Adult; Anesthetics, Local; Body Surface Area; Dermatitis, Contact; Drug Combinations; Drug Eruptions | 2013 |
Commentary: Serum lidocaine levels and cutaneous side effects after application of 23% lidocaine/7% tetracaine ointment to the face.
Topics: Anesthetics, Local; Drug Eruptions; Face; Female; Humans; Lidocaine; Male; Tetracaine | 2013 |
Type IV hypersensitivity to sodium metabisulfite in local anaesthetic.
Topics: Anesthetics, Local; Dermatitis, Allergic Contact; Drug Eruptions; Epinephrine; Humans; Hypersensitiv | 2004 |
Delayed-type hypersensitivity to mepivacaine with cross-reaction to lidocaine.
Topics: Anesthetics, Local; Case-Control Studies; Cross Reactions; Drug Eruptions; Female; Humans; Hypersens | 2005 |
Leg ulcer progression caused by topical anesthesia with EMLA cream.
Topics: Anesthetics, Local; Debridement; Diagnosis, Differential; Disease Progression; Drug Eruptions; Femal | 2008 |
Leg ulcer progression caused by topical anesthesia with EMLA cream.
Topics: Anesthetics, Local; Debridement; Diagnosis, Differential; Disease Progression; Drug Eruptions; Femal | 2008 |
Leg ulcer progression caused by topical anesthesia with EMLA cream.
Topics: Anesthetics, Local; Debridement; Diagnosis, Differential; Disease Progression; Drug Eruptions; Femal | 2008 |
Leg ulcer progression caused by topical anesthesia with EMLA cream.
Topics: Anesthetics, Local; Debridement; Diagnosis, Differential; Disease Progression; Drug Eruptions; Femal | 2008 |
A fixed drug eruption that developed cross-sensitivity among amide local anaesthetics, including mepivacaine hydrochloride, lidocaine hydrochloride and propitocaine hydrochloride.
Topics: Anesthetics, Local; Cross Reactions; Drug Eruptions; Humans; Lidocaine; Male; Mepivacaine; Middle Ag | 2008 |
[Allergic contact dermatitis from lidocaine in ear drops].
Topics: Acute Disease; Aged; Anesthetics, Local; Dermatitis, Allergic Contact; Drug Eruptions; Ear; Face; Hu | 2008 |
An unusual skin reaction following local anesthetic injection. Review of the literature and report of four cases.
Topics: Arthus Reaction; Child; Drug Eruptions; Drug Hypersensitivity; Drug Tolerance; Erythema; Female; Hum | 1980 |
Allergic contact dermatitis from prilocaine, one of the local anaesthetics in EMLA cream.
Topics: Aged; Anesthetics, Local; Dermatitis, Allergic Contact; Drug Combinations; Drug Eruptions; Foot Derm | 1994 |
Effects of intradermal lignocaine and mepivacaine on human cutaneous circulation in areas with histamine-induced neurogenic inflammation.
Topics: Adult; Drug Eruptions; Epinephrine; Female; Histamine; Humans; Injections, Intradermal; Lidocaine; M | 1993 |
Reaction to topical lignocaine in a patient with contact dermatitis.
Topics: Administration, Cutaneous; Adult; Dermatitis, Allergic Contact; Dermatitis, Occupational; Drug Erupt | 1993 |
Can injected lignocaine cause allergic contact dermatitis?
Topics: Administration, Cutaneous; Anesthetics, Local; Dermatitis, Allergic Contact; Drug Eruptions; Female; | 1996 |
Delayed-type hypersensitivity after subcutaneous administration of amide anesthetic.
Topics: Aged; Amides; Anesthetics, Local; Drug Eruptions; Drug Hypersensitivity; Female; Humans; Hypersensit | 1996 |
Delayed-type hypersensitivity to subcutaneous lidocaine with tolerance to articaine: confirmation by in vivo and in vitro tests.
Topics: Adult; Anesthetics, Local; Benzocaine; Bupivacaine; Carticaine; Cross Reactions; Dermatitis, Allergi | 1996 |
Fixed drug eruption induced by lidocaine.
Topics: Administration, Rectal; Adult; Anesthetics, Local; Dermatitis, Allergic Contact; Drug Eruptions; Fem | 1996 |
Simultaneous contact sensitivity due to lidocaine and crotamiton.
Topics: Allergens; Anesthetics, Local; Dermatitis, Allergic Contact; Drug Eruptions; Female; Humans; Lidocai | 1997 |
Petechial eruption after the application of EMLA cream.
Topics: Anesthetics, Combined; Anesthetics, Local; Child, Preschool; Drug Eruptions; Female; Humans; Infant; | 1998 |
Histopathology of an adverse reaction to a eutectic mixture of the local anesthetics lidocaine and prilocaine.
Topics: Anesthetics, Combined; Anesthetics, Local; Child; Child, Preschool; Dermis; Drug Eruptions; Epidermi | 1999 |
Acquired allergic reaction to topical anesthesia--a case report.
Topics: Adult; Anesthetics, Local; Benzocaine; Diagnosis, Differential; Drug Eruptions; Exanthema; Female; H | 1999 |
Hyperpigmentation following the use of Emla cream.
Topics: Anesthetics, Local; Black People; Child; Drug Eruptions; Humans; Hyperpigmentation; Lidocaine; Lidoc | 2001 |
EMLA cream-induced irritant contact dermatitis.
Topics: Acrodermatitis; Administration, Topical; Anesthetics, Local; Child; Dermatitis, Contact; Diagnosis, | 2002 |
Contact sensitivity to lignocaine and prilocaine.
Topics: Acute Disease; Administration, Topical; Adult; Cross Reactions; Dermatitis, Contact; Drug Eruptions; | 1990 |
Vascular response of human skin after analgesia with EMLA cream.
Topics: Adult; Analgesia; Anesthetics, Local; Drug Combinations; Drug Eruptions; Erythema; Female; Humans; L | 1989 |
An unusual cutaneous reaction to lignocaine.
Topics: Child; Drug Eruptions; Female; Humans; Lidocaine; Lip Diseases; Patch Tests; Pigmentation Disorders | 1987 |
'An unusual cutaneous reaction to lignocaine'.
Topics: Anesthesia, Dental; Child; Child, Preschool; Drug Eruptions; Female; Humans; Lidocaine; Male | 1987 |
Severe dermatologic reactions reported after treatment with tocainide.
Topics: Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Dermatitis, Exfoliative; Drug Eruptions; Ery | 1987 |
Tocainide: a severe adverse reaction.
Topics: Aged; Anti-Arrhythmia Agents; Drug Eruptions; Drug Hypersensitivity; Humans; Lidocaine; Male; Tocain | 1988 |
Adverse reactions to tocainide.
Topics: Anti-Arrhythmia Agents; Drug Eruptions; Female; Humans; Lidocaine; Male; Nervous System Diseases; To | 1985 |