Compounds > lidocaine
Page last updated: 2024-10-28

lidocaine and Delayed Hypersensitivity

lidocaine has been researched along with Delayed Hypersensitivity in 27 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Research Excerpts

ExcerptRelevanceReference
"A 43-year-old woman suffered from recurrent localized swellings and an eczematous dermatitis starting 1 day after an injection of lidocaine."3.69Delayed-type hypersensitivity to subcutaneous lidocaine with tolerance to articaine: confirmation by in vivo and in vitro tests. ( Bircher, AJ; Messmer, SL; Rufli, T; Surber, C, 1996)
"In a study of 7 cases of adverse reactions to local anaesthetics the early symptoms of toxicity (malaise, anxiety, feeling of impending death, peripheral paresthesias and tachycardia) are reviewed."1.26[Minor toxic effects of local anaesthetics. 7 cases (author's transl)]. ( Dry, J; Leynadier, F, 1980)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19908 (29.63)18.7374
1990's6 (22.22)18.2507
2000's10 (37.04)29.6817
2010's3 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dickison, P1
Smith, SD1
Hermann, R1
Lam, F1
Spackman, G1
Peters, CM1
Ririe, D1
Houle, TT1
Aschenbrenner, CA1
Eisenach, JC1
Evans, LA1
Pointing, J1
Wills, EJ1
Michalopoulos, J1
Adelstein, S1
Mackley, CL2
Marks, JG2
Anderson, BE1
Riemersma, WA1
Schuttelaar, ML1
Coenraads, PJ1
Sanchez-Morillas, L1
Martinez, JJ1
Martos, MR1
Gomez-Tembleque, P1
Andres, ER1
Hickey, JR1
Cook, SD1
Gutteridge, G1
Sansom, JE1
Amado, A1
Sood, A1
Taylor, JS1
Lachapelle, JM1
Tennstedt, D1
Dry, J1
Leynadier, F1
Wolf, SI1
Shier, JM1
Lampl, KL1
Schwartz, R1
Bassett, IB1
Delaney, TA1
Freeman, S1
Whalen, JD1
Dufresne, RG1
Bircher, AJ2
Messmer, SL1
Surber, C2
Rufli, T1
Scala, E1
Giani, M1
Pirrotta, L1
Guerra, EC1
Girardelli, CR1
De Pità, O1
Puddu, P1
Cetinkaya, F1
Brown, RS1
Paluvoi, S1
Choksi, S1
Burgess, CM1
Reece, ER1
Fregert, S1
Tegner, E1
Thelin, I1
Klein, CE1
Gall, H1
Björkstén, B1
Jung, B1
Tågsjö, EB1
Groth, O1
Müller, U1
Bircher, A1
Bischof, M1
Michaëlsson, G1
Ros, AM1
Shields, PW1
Lynas, RF1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy of Ethyl Chloride Topical Anesthesia Application on the Pain Perception During Intra-oral Injections in Children in Comparison to Benzocaine Gel- a Single-blinded Randomized Controlled Trial.[NCT06011005]42 participants (Anticipated)Interventional2023-09-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for lidocaine and Delayed Hypersensitivity

ArticleYear
Lidocaine hydrochloride.
    American journal of contact dermatitis : official journal of the American Contact Dermatitis Society, 2003, Volume: 14, Issue:4

    Topics: Allergens; Anesthetics, Local; Anti-Arrhythmia Agents; Humans; Hypersensitivity, Delayed; Lidocaine

2003

Trials

1 trial available for lidocaine and Delayed Hypersensitivity

ArticleYear
Delayed hypersensitivity responses in children after local cutaneous anesthesia.
    Acta paediatrica Scandinavica, 1987, Volume: 76, Issue:6

    Topics: Adolescent; Anesthesia, Local; Antigens; Child; Clinical Trials as Topic; Humans; Hypersensitivity,

1987

Other Studies

25 other studies available for lidocaine and Delayed Hypersensitivity

ArticleYear
Biting down on the truth: A case of a delayed hypersensitivity reaction to lidocaine.
    The Australasian journal of dermatology, 2019, Volume: 60, Issue:1

    Topics: Aged; Anesthetics, Local; Drug Eruptions; Erythema; Humans; Hypersensitivity, Delayed; Lidocaine; Ma

2019
CAT of the Month (Critically Appraised Topics): True Allergic Reaction to Amide Local Anesthetics such as Lidocaine is Confirmed by Immunologic Testing (UT CAT# 3062).
    Texas dental journal, 2016, Volume: 133, Issue:11

    Topics: Adult; Amides; Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Hypersensitivity, Delayed;

2016
Nociceptor-selective peripheral nerve block induces delayed mechanical hypersensitivity and neurotoxicity in rats.
    Anesthesiology, 2014, Volume: 120, Issue:4

    Topics: Anesthetics, Combined; Anesthetics, Local; Animals; Behavior, Animal; Capsaicin; Disease Models, Ani

2014
Recurrent facial swelling following dental procedures.
    The Medical journal of Australia, 2002, Nov-04, Volume: 177, Issue:9

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Drug Hypersensitivity; Edema; Face; Humans; Hypersens

2002
Delayed-type hypersensitivity to lidocaine.
    Archives of dermatology, 2003, Volume: 139, Issue:3

    Topics: Adult; Aged; Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Hypersensitivity, Delayed; I

2003
Type IV hypersensitivity to sodium metabisulfite in local anaesthetic.
    Contact dermatitis, 2004, Volume: 51, Issue:3

    Topics: Anesthetics, Local; Dermatitis, Allergic Contact; Drug Eruptions; Epinephrine; Humans; Hypersensitiv

2004
Delayed-type hypersensitivity to mepivacaine with cross-reaction to lidocaine.
    Contact dermatitis, 2005, Volume: 53, Issue:6

    Topics: Anesthetics, Local; Case-Control Studies; Cross Reactions; Drug Eruptions; Female; Humans; Hypersens

2005
Delayed hypersensitivity following intravenous lidocaine.
    Contact dermatitis, 2006, Volume: 54, Issue:4

    Topics: Aged, 80 and over; Anesthetics, Local; Female; Humans; Hypersensitivity, Delayed; Injections, Intrav

2006
Contact allergy to lidocaine: a report of sixteen cases.
    Dermatitis : contact, atopic, occupational, drug, 2007, Volume: 18, Issue:4

    Topics: Adult; Aged; Anesthetics, Local; Balsams; Dermatitis, Allergic Contact; Female; Humans; Hypersensiti

2007
An anatomo-clinical study of delayed skin allergic reactions to nickel following intradermal injections of lidocaïne with a Dermo-jet.
    Contact dermatitis, 1982, Volume: 8, Issue:3

    Topics: Biopsy; Dermatitis, Contact; Female; Humans; Hypersensitivity, Delayed; Injections, Jet; Lidocaine;

1982
[Minor toxic effects of local anaesthetics. 7 cases (author's transl)].
    La Nouvelle presse medicale, 1980, May-03, Volume: 9, Issue:20

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Anxiety; Drug Hypersensitivity; Female; Humans; Hyper

1980
EMLA cream for painless skin testing: a preliminary report.
    Annals of allergy, 1994, Volume: 73, Issue:1

    Topics: Anesthetics, Local; Child; Child, Preschool; Drug Combinations; Humans; Hypersensitivity, Delayed; I

1994
Can injected lignocaine cause allergic contact dermatitis?
    The Australasian journal of dermatology, 1996, Volume: 37, Issue:3

    Topics: Administration, Cutaneous; Anesthetics, Local; Dermatitis, Allergic Contact; Drug Eruptions; Female;

1996
Delayed-type hypersensitivity after subcutaneous administration of amide anesthetic.
    Archives of dermatology, 1996, Volume: 132, Issue:10

    Topics: Aged; Amides; Anesthetics, Local; Drug Eruptions; Drug Hypersensitivity; Female; Humans; Hypersensit

1996
Delayed-type hypersensitivity to subcutaneous lidocaine with tolerance to articaine: confirmation by in vivo and in vitro tests.
    Contact dermatitis, 1996, Volume: 34, Issue:6

    Topics: Adult; Anesthetics, Local; Benzocaine; Bupivacaine; Carticaine; Cross Reactions; Dermatitis, Allergi

1996
Anaphylactic reaction to lidocaine.
    Australian dental journal, 1999, Volume: 44, Issue:1

    Topics: Adolescent; Anaphylaxis; Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Hypersensitivity

1999
Simultaneous [correction of Spontaneous] allergy to ampicillin and local anesthetics.
    Allergy, 2001, Volume: 56, Issue:5

    Topics: Ampicillin; Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Hypersensitivity, Delayed; In

2001
Sensitivity to local anaesthetics among asthmatic children.
    International journal of paediatric dentistry, 2001, Volume: 11, Issue:6

    Topics: Adolescent; Allergens; Anesthetics, Local; Animals; Asthma; Child; Drug Hypersensitivity; Female; Hu

2001
Evaluating a dental patient for local anesthesia allergy.
    Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995), 2002, Volume: 23, Issue:2

    Topics: Aged; Allergens; Anesthesia, Dental; Anesthetics, Local; Drug Hypersensitivity; Exanthema; Humans; H

2002
Contact allergy to lidocaine.
    Contact dermatitis, 1979, Volume: 5, Issue:3

    Topics: Adult; Dermatitis, Atopic; Female; Hemorrhoids; Humans; Hypersensitivity, Delayed; Lidocaine; Prurit

1979
Type IV allergy to amide-type local anesthetics.
    Contact dermatitis, 1991, Volume: 25, Issue:1

    Topics: Anesthetics, Local; Cross Reactions; Drug Hypersensitivity; Female; Humans; Hypersensitivity, Delaye

1991
[Allergic angioedema after local dental anesthesia and a hyaluronidase-containing preanesthetic injection solution].
    Schweizerische medizinische Wochenschrift, 1986, Dec-20, Volume: 116, Issue:51

    Topics: Adult; Anesthesia, Dental; Anesthesia, Local; Angioedema; Drug Hypersensitivity; Female; Humans; Hya

1986
Familial localized heat urticaria of delayed type.
    Acta dermato-venereologica, 1971, Volume: 51, Issue:4

    Topics: Acetylcholine; Antigen-Antibody Reactions; Atropine; Basophils; Biopsy; Bradykinin; Child; Female; H

1971
Local anaesthetic sensitivity. Case report.
    Australian dental journal, 1972, Volume: 17, Issue:1

    Topics: Antigen-Antibody Reactions; Asthma; Drug Hypersensitivity; Edema; Epinephrine; Female; Humans; Hyper

1972
A suspected allergic reaction to lidocaine.
    Anesthesiology, 1969, Volume: 31, Issue:4

    Topics: Anaphylaxis; Drug Hypersensitivity; Humans; Hypersensitivity, Delayed; Lidocaine; Male; Middle Aged;

1969