lidocaine has been researched along with Death, Sudden in 39 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Death, Sudden: The abrupt cessation of all vital bodily functions, manifested by the permanent loss of total cerebral, respiratory, and cardiovascular functions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of our study was to determine the morbidity and mortality in initially stable patients presenting to paramedics with chest pain; to examine possible beneficial effects of its use, including reduction of sudden death syndrome in the prehospital and emergency department setting; and to determine if prophylactic lidocaine is associated with adverse effects in this patient population." | 9.06 | Prehospital prophylactic lidocaine does not favorably affect outcome in patients with chest pain. ( Aufderheide, TP; Chapman, PD; Haecker, P; Hargarten, K; Mateer, JR; Olson, DW; Stueven, HA; Waite, EM, 1990) |
| "The prophylactic use of lidocaine in the patient with cardiac chest pain has been reported to reduce the incidence of sudden death from ventricular dysrhythmias in the hospital setting, but few studies have been done in the early prehospital phase." | 9.06 | Prophylactic lidocaine in the prehospital patient with chest pain of suspected cardiac origin. ( Aprahamian, C; Darin, J; Hargarten, KM; Mateer, JR; Stueven, HA; Thompson, BM, 1986) |
| "Tocainide was administered to 228 patients referred for treatment of recurrent ventricular tachyarrhythmias that were refractory to therapy with conventional antiarrhythmic drugs." | 7.67 | Short- and long-term therapy with tocainide for malignant ventricular tachyarrhythmias. ( Hohnloser, SH; Lange, HW; Lown, B; Podrid, PJ; Raeder, EA, 1986) |
| "Twenty-five patients entered a prospective study to assess the usefulness of atropine and lignocaine autoinjectors for coronary events after discharge from hospital after a definite, complicated myocardial infarction." | 7.66 | Use of lignocaine and atropine autoinjectors for patients at high risk of sudden death and reinfarction after myocardial infarction. ( Baker, G; Hamer, A; Hunt, D; Sloman, G, 1981) |
| "Eight patients died; 3 were sudden deaths in 13 +/- 5 months, a 17% incidence." | 5.27 | Lorcainide therapy for the high-risk patient post myocardial infarction. ( Butler, B; Flowers, D; Keefe, D; Miura, DS; Somberg, JC; Tepper, D; Torres, V, 1984) |
| "The purpose of our study was to determine the morbidity and mortality in initially stable patients presenting to paramedics with chest pain; to examine possible beneficial effects of its use, including reduction of sudden death syndrome in the prehospital and emergency department setting; and to determine if prophylactic lidocaine is associated with adverse effects in this patient population." | 5.06 | Prehospital prophylactic lidocaine does not favorably affect outcome in patients with chest pain. ( Aufderheide, TP; Chapman, PD; Haecker, P; Hargarten, K; Mateer, JR; Olson, DW; Stueven, HA; Waite, EM, 1990) |
| "The prophylactic use of lidocaine in the patient with cardiac chest pain has been reported to reduce the incidence of sudden death from ventricular dysrhythmias in the hospital setting, but few studies have been done in the early prehospital phase." | 5.06 | Prophylactic lidocaine in the prehospital patient with chest pain of suspected cardiac origin. ( Aprahamian, C; Darin, J; Hargarten, KM; Mateer, JR; Stueven, HA; Thompson, BM, 1986) |
| "Tocainide was administered to 228 patients referred for treatment of recurrent ventricular tachyarrhythmias that were refractory to therapy with conventional antiarrhythmic drugs." | 3.67 | Short- and long-term therapy with tocainide for malignant ventricular tachyarrhythmias. ( Hohnloser, SH; Lange, HW; Lown, B; Podrid, PJ; Raeder, EA, 1986) |
| "The efficacy of verapamil and lidocaine for treating ischemia-induced arrhythmias was determined in a conscious canine model with a previous myocardial infarction remote from the ischemic area." | 3.67 | Effects of verapamil and lidocaine in a canine model of sudden coronary death. ( Hoffman, BF; Legenza, M; Southworth, SR; Temesy-Armos, PN, 1985) |
| "Twenty-five patients entered a prospective study to assess the usefulness of atropine and lignocaine autoinjectors for coronary events after discharge from hospital after a definite, complicated myocardial infarction." | 3.66 | Use of lignocaine and atropine autoinjectors for patients at high risk of sudden death and reinfarction after myocardial infarction. ( Baker, G; Hamer, A; Hunt, D; Sloman, G, 1981) |
| "Many sudden deaths are presumed to be due to an arrhythmia, but the drugs best known for antiarrhythmic activity, the local anesthetic agents, have not been suitable prophylactic agents because of their toxicities and other undesirable pharmacologic characteristics." | 2.65 | Selection of an antiarrhythmic drug for a sudden-death-prevention trial. ( Duff, HJ; Oates, JA; Roden, DM; Woosley, RL, 1982) |
| " If side effects intervene that may cause continued therapy to be intolerable, changing the antiarrhythmic agent, as opposed to decreasing the dosage to an ineffective range, may be appropriate." | 1.27 | New directions in antiarrhythmic drug therapy. ( Somberg, JC, 1984) |
| "Eight patients died; 3 were sudden deaths in 13 +/- 5 months, a 17% incidence." | 1.27 | Lorcainide therapy for the high-risk patient post myocardial infarction. ( Butler, B; Flowers, D; Keefe, D; Miura, DS; Somberg, JC; Tepper, D; Torres, V, 1984) |
| "Malignant ventricular arrhythmias appearing during acute myocardial ischaemia, are the most frequent mechanism of sudden death." | 1.27 | Ventricular arrhythmias during acute myocardial ischaemia in man. The role and significance of R-ST-T alternans and the prevention of ischaemic sudden death by medical treatment. ( Campana, C; Chimienti, M; Falcone, C; Guasti, L; Klersy, C; Marangoni, E; Panciroli, C; Previtali, M; Regazzi Bonora, M; Salerno, JA, 1986) |
| "Of particular importance are the arrhythmias observed immediately after experimentally induced acute myocardial infarction (AMI)." | 1.25 | Pharmacological modification of arrhythmias after experimentally induced acute myocardial infarction. Drugs acting on the nervous system. ( Kniffen, FJ; Lucchesi, BR, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 36 (92.31) | 18.7374 |
| 1990's | 3 (7.69) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| SUNSHINE, I | 1 |
| FIKE, WW | 1 |
| Somberg, JC | 2 |
| Woosley, RL | 1 |
| Roden, DM | 2 |
| Duff, HJ | 1 |
| Oates, JA | 1 |
| Butler, B | 1 |
| Torres, V | 1 |
| Flowers, D | 1 |
| Tepper, D | 1 |
| Keefe, D | 1 |
| Miura, DS | 1 |
| Shand, DG | 1 |
| Pritchett, EL | 1 |
| Hammill, SC | 1 |
| Stargel, WW | 1 |
| Wagner, GS | 2 |
| Pearl, WR | 1 |
| Sloman, G | 1 |
| Hamer, A | 1 |
| Baker, G | 1 |
| Hunt, D | 1 |
| Burlington, B | 1 |
| Freed, CR | 1 |
| Killip, T | 1 |
| Schroeder, JS | 2 |
| Alexander, S | 1 |
| Lucchesi, BR | 1 |
| Kniffen, FJ | 1 |
| Fejfar, Z | 1 |
| Vrána, M | 1 |
| Hess, L | 1 |
| Vránová, Z | 1 |
| Blazek, Z | 1 |
| Berntsen, RF | 1 |
| Rasmussen, K | 1 |
| Bjørnstad, JF | 1 |
| Hargarten, K | 1 |
| Chapman, PD | 1 |
| Stueven, HA | 2 |
| Waite, EM | 1 |
| Mateer, JR | 2 |
| Haecker, P | 1 |
| Aufderheide, TP | 1 |
| Olson, DW | 1 |
| Podrid, PJ | 2 |
| Hargarten, KM | 1 |
| Aprahamian, C | 1 |
| Thompson, BM | 1 |
| Darin, J | 1 |
| Geng, WQ | 1 |
| Hohnloser, SH | 1 |
| Lange, HW | 1 |
| Raeder, EA | 1 |
| Lown, B | 1 |
| Barnfield, C | 1 |
| Kemmenoe, AV | 1 |
| Mohiuddin, SM | 1 |
| Esterbrooks, D | 1 |
| Mooss, AN | 1 |
| Dahl, JM | 1 |
| Hilleman, DE | 1 |
| Szekeres, L | 1 |
| Salerno, JA | 1 |
| Previtali, M | 1 |
| Panciroli, C | 1 |
| Klersy, C | 1 |
| Chimienti, M | 1 |
| Regazzi Bonora, M | 1 |
| Marangoni, E | 1 |
| Falcone, C | 1 |
| Guasti, L | 1 |
| Campana, C | 1 |
| Temesy-Armos, PN | 1 |
| Legenza, M | 1 |
| Southworth, SR | 1 |
| Hoffman, BF | 1 |
| Stuart, KL | 2 |
| Bras, G | 1 |
| Yu, PN | 1 |
| Chung, EK | 1 |
| Burchell, HB | 1 |
| Valentine, PA | 1 |
| Frew, JL | 1 |
| Mashford, ML | 1 |
| Sloman, JG | 1 |
| Lee, KT | 1 |
| Lee, WM | 1 |
| Han, J | 1 |
| Jarmolych, J | 1 |
| Bishop, MB | 1 |
| Goel, BG | 1 |
| Surawicz, B | 1 |
| McRae, JR | 1 |
| Rogers, MC | 1 |
| Canent, RV | 1 |
| Rydén, L | 1 |
| Werkö, L | 1 |
| Parkinson, PI | 1 |
| Wattie, WJ | 1 |
| Kirk, GM | 1 |
| Szczeklik, A | 1 |
| Wrabec, K | 1 |
| Miller, BR | 1 |
| Moseley, HS | 1 |
| DaCosta, LR | 1 |
| Sandison, JW | 1 |
4 reviews available for lidocaine and Death, Sudden
| Article | Year |
|---|---|
Pharmacokinetic studies: their role in determining therapeutic efficacy of agents designed to prevent sudden death.
Topics: Administration, Oral; Anti-Arrhythmia Agents; Coronary Disease; Death, Sudden; Dose-Response Relatio | 1982 |
The role of antiarrhythmic drugs in prevention of sudden cardiac death.
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Cardiac Comple | 1985 |
The prophylactic use of anti-arrhythmic drugs in acute myocardial infarction.
Topics: Acute Disease; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atropine; Bradycardia; Death, Sud | 1973 |
Salvaging the postinfarct heart. The Postgraduate Medicine Lecture.
Topics: Anticoagulants; Arrhythmias, Cardiac; Assisted Circulation; Bretylium Compounds; Coronary Artery Byp | 1974 |
5 trials available for lidocaine and Death, Sudden
| Article | Year |
|---|---|
Selection of an antiarrhythmic drug for a sudden-death-prevention trial.
Topics: Acecainide; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneac | 1982 |
Prehospital prophylactic lidocaine does not favorably affect outcome in patients with chest pain.
Topics: Chest Pain; Death, Sudden; Emergency Medical Services; Humans; Incidence; Infusions, Intravenous; In | 1990 |
The role of antiarrhythmic drugs in prevention of sudden cardiac death.
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Cardiac Comple | 1985 |
Prophylactic lidocaine in the prehospital patient with chest pain of suspected cardiac origin.
Topics: Adult; Age Factors; Aged; Angina, Unstable; Arrhythmias, Cardiac; Blood Pressure; Cardiac Complexes, | 1986 |
Lidocaine in the prevention of sudden death in the pre-hospital phase of acute infarction. A double-blind study.
Topics: Age Factors; Aged; Blood Pressure; Clinical Trials as Topic; Death, Sudden; Drug Evaluation; Female; | 1974 |
31 other studies available for lidocaine and Death, Sudden
| Article | Year |
|---|---|
VALUE OF THIN-LAYER CHROMATOGRAPHY IN TWO FATAL CASES OF INTOXICATION DUE TO LIDOCAINE AND MEPIVACAINE.
Topics: Analgesics; Breast; Chromatography; Chromatography, Thin Layer; Death; Death, Sudden; Dextropropoxyp | 1964 |
New directions in antiarrhythmic drug therapy.
Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Benz | 1984 |
Lorcainide therapy for the high-risk patient post myocardial infarction.
Topics: Aged; Anti-Arrhythmia Agents; Benzeneacetamides; Blood Pressure; Death, Sudden; Drug Evaluation; Ele | 1984 |
Massive lidocaine overdose.
Topics: Death, Sudden; Humans; Lidocaine; Male; Middle Aged; Myocardial Infarction | 1982 |
Use of lignocaine and atropine autoinjectors for patients at high risk of sudden death and reinfarction after myocardial infarction.
Topics: Aged; Atropine; Death, Sudden; Female; Humans; Lidocaine; Male; Myocardial Infarction; Patient Educa | 1981 |
Massive overdose and death from prophylactic lidocaine.
Topics: Arrhythmias, Cardiac; Death, Sudden; Humans; Lidocaine; Male; Middle Aged | 1980 |
Arrhythmias in myocardial infarction.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atropine; Bradycardia; Cardiac Complexes, Premature; D | 1976 |
Should premature ventricular beats be treated in the ambulatory patient? A protagonist's view.
Topics: Adult; Aged; Alprenolol; Ambulatory Care; Cardiac Complexes, Premature; Death, Sudden; Electrocardio | 1977 |
Sudden death.
Topics: Angina Pectoris; Arrhythmias, Cardiac; Coronary Artery Bypass; Coronary Care Units; Coronary Disease | 1977 |
Ventricular premature beats. When is drug treatment justified?
Topics: Adult; Arrhythmias, Cardiac; Death, Sudden; Electrocardiography; Female; Heart Valve Diseases; Heart | 1976 |
Pharmacological modification of arrhythmias after experimentally induced acute myocardial infarction. Drugs acting on the nervous system.
Topics: Acute Disease; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Compounds; Chlordiaz | 1975 |
Prevention of sudden coronary death.
Topics: Adrenergic beta-Antagonists; Analgesics; Animals; Anti-Anxiety Agents; Anti-Arrhythmia Agents; Benzo | 1991 |
Monitoring a randomized clinical trial for futility: the north-Norwegian lidocaine intervention trial.
Topics: Binomial Distribution; Clinical Trials as Topic; Death, Sudden; Humans; Incidence; Lidocaine; Models | 1991 |
Antiarrhythmic drugs. Clinical pharmacology of the old and the new agents.
Topics: Acecainide; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Death, Sudden; Delayed-Action | 1985 |
[Electrocardiographic changes before and after the extraction of teeth in patients with heart disease].
Topics: Adult; Aged; Aged, 80 and over; Cardiac Complexes, Premature; Coronary Disease; Death, Sudden; Elect | 1986 |
Short- and long-term therapy with tocainide for malignant ventricular tachyarrhythmias.
Topics: Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Death, Sudden; Female; Heart Ventricles; Humans; Li | 1986 |
A sudden death due to tocainide overdose.
Topics: Aged; Death, Sudden; Humans; Lidocaine; Liver; Male; Tocainide | 1986 |
Efficacy and tolerance of tocainide during long-term treatment of malignant ventricular arrhythmias.
Topics: Death, Sudden; Female; Follow-Up Studies; Humans; Kinetics; Lidocaine; Male; Middle Aged; Recurrence | 1987 |
Cardioprotection by anti-ischaemic and cytoprotective drugs.
Topics: Animals; Arrhythmias, Cardiac; Coronary Disease; Death, Sudden; Dietary Fats; Epoprostenol; Humans; | 1987 |
Ventricular arrhythmias during acute myocardial ischaemia in man. The role and significance of R-ST-T alternans and the prevention of ischaemic sudden death by medical treatment.
Topics: Angina Pectoris, Variant; Arrhythmias, Cardiac; Coronary Disease; Death, Sudden; Diltiazem; Electroc | 1986 |
Effects of verapamil and lidocaine in a canine model of sudden coronary death.
Topics: Animals; Arrhythmias, Cardiac; Death, Sudden; Dogs; Female; Heart Conduction System; Heart Rate; Lid | 1985 |
Prognosis of idiopathic cardiomegaly in Jamaica with reference to the coronary arteries and other factors.
Topics: Adult; Cardiac Complexes, Premature; Cardiomyopathies; Coronary Disease; Coronary Vessels; Death, Su | 1971 |
Prehospital care of acute myocardial infarction.
Topics: Cardiac Complexes, Premature; Death, Sudden; Electrocardiography; Emergency Medical Services; Health | 1972 |
Experimental model for study of "sudden death" from ventricular fibrillation or asystole.
Topics: Angiocardiography; Animals; Aorta, Thoracic; Arrhythmias, Cardiac; Autopsy; Coronary Angiography; Co | 1973 |
Pathogenesis and prevention of sudden cardiac death.
Topics: Animals; Arteriosclerosis; Coronary Disease; Death, Sudden; Dogs; Heart; Humans; Lidocaine; Potassiu | 1974 |
Paroxysmal familial ventricular fibrillation.
Topics: Child; Death, Sudden; Electrocardiography; Electrophysiology; Humans; Lidocaine; Male; Propranolol; | 1974 |
[Arrhythmia. 1. Arrhythmia as a cause of sudden death in acute myocardial infarction--prophylaxis].
Topics: Arrhythmias, Cardiac; Coronary Care Units; Death, Sudden; Humans; Lidocaine; Mobile Health Units; My | 1971 |
The coronary care unit at Palmerston North Hospital.
Topics: Arrhythmias, Cardiac; Atropine; Coronary Disease; Death, Sudden; Electrocardiography; Female; Hospit | 1967 |
[Arrhythmia as a cause of sudden death in cardiac infarction].
Topics: Aged; Death, Sudden; Electric Countershock; Female; Heart Arrest; Humans; Lidocaine; Male; Middle Ag | 1969 |
[Prevention of arrhythmia as a cause of sudden death].
Topics: Adams-Stokes Syndrome; Arrhythmias, Cardiac; Death, Sudden; Humans; Lidocaine; Propranolol | 1969 |
The prognosis in idiopathic cardiomyopathy in Jamaica.
Topics: Arrhythmias, Cardiac; Autopsy; Cardiomyopathies; Death, Sudden; Electrocardiography; Heart Failure; | 1970 |