Page last updated: 2024-10-28

lidocaine and Cyanosis

lidocaine has been researched along with Cyanosis in 17 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Cyanosis: A bluish or purplish discoloration of the skin and mucous membranes due to an increase in the amount of deoxygenated hemoglobin in the blood or a structural defect in the hemoglobin molecule.

Research Excerpts

ExcerptRelevanceReference
"Neonatal methemoglobinemia is a rare and potentially fatal complication of local anesthetics, particularly prilocaine, administered to the mother during childbirth."8.02[Unexplained cyanosis in two newborns: neonatal methemoglobinemia after maternal perineal infiltration of prilocaine]. ( Alers, NO; Leijten, A; Ten Brink, F; van de Laar, R; van der Heijden, HHACM; Wieland, BV, 2021)
"Neonatal methemoglobinemia is a rare and potentially fatal complication of local anesthetics, particularly prilocaine, administered to the mother during childbirth."4.02[Unexplained cyanosis in two newborns: neonatal methemoglobinemia after maternal perineal infiltration of prilocaine]. ( Alers, NO; Leijten, A; Ten Brink, F; van de Laar, R; van der Heijden, HHACM; Wieland, BV, 2021)
"Methemoglobinemia (MetHb) after exposure to benzocaine (BZC) has been reported for more than 50 years, however the pathophysiologic mechanism has not been previously established."3.80Identification of N-Hydroxy-para-aminobenzoic acid in a cyanotic child after benzocaine exposure. ( Casavant, MJ; Gerona, RR; Ho, RY; Russell, JL; Spiller, HA, 2014)
" Due to the application of EMLA(R) on the injured skin and exceeding the recommended doses of prilocaine and lidocaine the child developed symptomatic methemoglobinemia."3.75[Methemoglobin intoxication by prilocaine in EMLA. Accidental intoxication of an infant with scald injuries]. ( Book, A; Fehlandt, C; Krija, M; Pappert, D; Radke, M, 2009)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19909 (52.94)18.7374
1990's1 (5.88)18.2507
2000's3 (17.65)29.6817
2010's3 (17.65)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Wieland, BV1
Leijten, A1
van der Heijden, HHACM1
van de Laar, R1
Ten Brink, F1
Alers, NO1
Shamriz, O1
Cohen-Glickman, I1
Reif, S1
Shteyer, E1
Dutra, RM1
Neves, IL1
Neves, RS1
Atik, E1
Santos, Ude P1
Spiller, HA1
Russell, JL1
Casavant, MJ1
Ho, RY1
Gerona, RR1
Book, A1
Fehlandt, C1
Krija, M1
Radke, M1
Pappert, D1
Picton, P1
Wilkins, AN1
MIYABE, I1
SUGIYAMA, S1
SCOTT, DB1
OWEN, JA1
RICHMOND, J1
KLINGENSTROEM, P1
WESTERMARK, L2
HJELM, M1
HOLMDAHL, MH1
Voelker, CA1
Brown, L1
Hinson, RM1
Burrows, FA1
Lerman, J1
LeDez, KM1
Strong, HA1
Mercereau, DA1
Fuller, HD1
Jenkins, AV1
Sammons, HG1
Klingenström, P1
Nylén, B1
Magora, F1
Davis, E1

Reviews

1 review available for lidocaine and Cyanosis

ArticleYear
Methemoglobinemia induced by lidocaine-prilocaine cream.
    The Israel Medical Association journal : IMAJ, 2014, Volume: 16, Issue:4

    Topics: Anesthetics, Combined; Anesthetics, Local; Child; Cyanosis; Enzyme Inhibitors; Female; Humans; Lidoc

2014

Trials

1 trial available for lidocaine and Cyanosis

ArticleYear
Experimental and clinical investigations of the local vasoconstrictive effect of two new derivatives of pituitary posterior lobe hormones.
    Plastic and reconstructive surgery, 1967, Volume: 39, Issue:5

    Topics: Clinical Trials as Topic; Cyanosis; Epinephrine; Humans; Lidocaine; Lysine; Ornithine; Oxytocin; Phe

1967

Other Studies

15 other studies available for lidocaine and Cyanosis

ArticleYear
[Unexplained cyanosis in two newborns: neonatal methemoglobinemia after maternal perineal infiltration of prilocaine].
    Nederlands tijdschrift voor geneeskunde, 2021, 07-01, Volume: 165

    Topics: Anesthetics, Local; Cyanosis; Humans; Infant, Newborn; Lidocaine; Methemoglobinemia; Prilocaine

2021
Peripheral oxygen saturation, heart rate, and blood pressure during dental treatment of children with cyanotic congenital heart disease.
    Clinics (Sao Paulo, Brazil), 2014, Volume: 69, Issue:5

    Topics: Anesthetics, Local; Blood Pressure; Child; Cyanosis; Dental Anxiety; Heart Defects, Congenital; Hear

2014
Identification of N-Hydroxy-para-aminobenzoic acid in a cyanotic child after benzocaine exposure.
    Clinical toxicology (Philadelphia, Pa.), 2014, Volume: 52, Issue:9

    Topics: 4-Aminobenzoic Acid; Acetaminophen; Administration, Topical; Benzocaine; Bupivacaine; Child; Cyanosi

2014
[Methemoglobin intoxication by prilocaine in EMLA. Accidental intoxication of an infant with scald injuries].
    Der Anaesthesist, 2009, Volume: 58, Issue:4

    Topics: Administration, Topical; Anesthetics, Local; Bandages; Burns; Cyanosis; Diagnosis, Differential; Hum

2009
The use of lubricants to achieve tracheal intubation in neonates and infants.
    Paediatric anaesthesia, 2002, Volume: 12, Issue:8

    Topics: Anesthetics, Local; Benzocaine; Cyanosis; Female; Humans; Infant, Newborn; Intubation, Intratracheal

2002
[CASE OF SUCCESSFUL TREATMENT OF SHOCK IN TONSILLECTOMY AND MEASURES FOR PREVENTING IT].
    Jibi inkoka Otolaryngology, 1963, Volume: 35

    Topics: Blood Sedimentation; Blood Transfusion; Caffeine; Cyanosis; Drug Hypersensitivity; Electrocardiograp

1963
METHAEMOGLOBINAEMIA DUE TO PRILOCAINE.
    Lancet (London, England), 1964, Oct-03, Volume: 2, Issue:7362

    Topics: Anesthetics; Anesthetics, Local; Cyanosis; Humans; Lidocaine; Methemoglobinemia; Prilocaine; Toxicol

1964
LOCAL TISSUE-OXYGEN TENSION AFTER ADRENALINE, NORADRENALINE AND OCTAPRESSIN IN LOCAL ANAESTHESIA.
    Acta anaesthesiologica Scandinavica, 1964, Volume: 8

    Topics: Anesthesia; Anesthesia, Local; Arginine Vasopressin; Biomedical Research; Cyanosis; Epinephrine; Fel

1964
BIOCHEMICAL EFFECTS OF AROMATIC AMINES. II. CYANOSIS, METHAEMOGLOBINAEMIA AND HEINZ-BODY FORMATION INDUCED BY A LOCAL ANAESTHETIC AGENT (PRILOCAINE).
    Acta anaesthesiologica Scandinavica, 1965, Volume: 9

    Topics: Alanine Transaminase; Amines; Anesthesia, Local; Anesthetics, Local; Bilirubin; Blood; Creatine; Cre

1965
Perioperatively acquired methaemoglobinaemia in a preterm infant.
    Paediatric anaesthesia, 2002, Volume: 12, Issue:3

    Topics: Anesthetics, Local; Benzocaine; Cyanosis; Diseases in Twins; Female; Humans; Infant, Newborn; Infant

2002
Alpha 1-acid glycoprotein and the binding of lidocaine in children with congenital heart disease.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1990, Volume: 37, Issue:8

    Topics: Adolescent; Alpha-Globulins; Analysis of Variance; Beta-Globulins; Blood Proteins; Child; Child, Pre

1990
Brain-stem anesthesia complicating retrobulbar block.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1989, Volume: 24, Issue:4

    Topics: Aged; Anesthesia, Local; Brain Stem; Cataract Extraction; Cyanosis; Diagnosis, Differential; Humans;

1989
Cyanosis of the hands following the use of alphaprodine in dental anaesthesia.
    Canadian Anaesthetists' Society journal, 1986, Volume: 33, Issue:2

    Topics: Adolescent; Alphaprodine; Anesthesia, Dental; Anesthesia, Inhalation; Anesthesia, Intravenous; Anest

1986
Carbon dioxide elimination during bronchoscopy. A comparison of two alternative general anaesthetic techniques.
    British journal of anaesthesia, 1968, Volume: 40, Issue:7

    Topics: Analysis of Variance; Anesthesia, General; Apnea; Arrhythmias, Cardiac; Blood Specimen Collection; B

1968
The effect of cervico-thoracic sympathetic block on the small blood vessels.
    Angiology, 1966, Volume: 17, Issue:8

    Topics: Adolescent; Adult; Aged; Autonomic Nerve Block; Blood Circulation; Blood Flow Velocity; Capillaries;

1966