lidocaine has been researched along with Critical Illness in 13 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Critical Illness: A disease or state in which death is possible or imminent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the effectiveness of intravenous lidocaine and intravenous morphine in decreasing pain in patients with critical limb ischaemia." | 9.20 | Comparison of intravenous lidocaine versus morphine in alleviating pain in patients with critical limb ischaemia. ( Aghaie Meybodi, M; Saeedi, M; Shakoor, D; Vahidi, E, 2015) |
| "To compare the effectiveness of intravenous lidocaine and intravenous morphine in decreasing pain in patients with critical limb ischaemia." | 5.20 | Comparison of intravenous lidocaine versus morphine in alleviating pain in patients with critical limb ischaemia. ( Aghaie Meybodi, M; Saeedi, M; Shakoor, D; Vahidi, E, 2015) |
| " Instead of using deep sedation and neuromuscular blockade, the authors hypothesized that perineural administration of lidocaine around the phrenic nerve would reduce tidal volume (VT) and peak transpulmonary pressure in spontaneously breathing patients with acute respiratory distress syndrome." | 4.12 | Phrenic Nerve Block and Respiratory Effort in Pigs and Critically Ill Patients with Acute Lung Injury. ( Adkson Sales Lima, C; Amato, MBP; Brochard, L; Costa, ELV; Goligher, EC; Ho, YL; Morais, CCA; Nakamura, MAM; Pereira, SM; Ranzani, OT; Sinedino, BE; Sklar, MC; Taniguchi, LU; Tucci, MR; Vieira, JE, 2022) |
| "To evaluate the pharmacokinetic parameters of morphine and lidocaine after a single intravenous dose in critically ill patients." | 2.69 | The pharmacokinetics of morphine and lidocaine in critically ill patients. ( Almog, S; Berkenstadt, H; Ezra, D; Mayan, H; Perel, A; Rotenberg, M; Segal, E, 1999) |
| "Bilirubin values were elevated in the non-survivor group (median: 2." | 2.68 | Lignocaine metabolite formation: an indicator for liver dysfunction and predictor of survival in surgical intensive care patients. ( Böhrer, H; Böttiger, BW; Martin, E; Schmidt, H; Schröter, J; Wandel, C, 1995) |
| "the day of trauma in most elderly, whereas minor changes were observed in the young." | 1.31 | MEGX disposition in critically-ill trauma patients: subsequent assessments during the first week following trauma. ( Baldassarre, M; Furlanut, M; Licari, M; Pea, F, 2002) |
| "Monoethylglycinexylidide (MEGX) is a hepatic metabolite of lidocaine, used clinically to determine graft function following hepatic transplantation." | 1.28 | Monoethylglycinexylidide production parallels changes in hepatic blood flow and oxygen delivery in lung injury managed with positive end-expiratory pressure. ( Branson, RD; Davis, K; Johnson, DJ; Purcell, PN; Schroeder, TJ, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (38.46) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Pereira, SM | 1 |
| Sinedino, BE | 1 |
| Costa, ELV | 1 |
| Morais, CCA | 1 |
| Sklar, MC | 1 |
| Adkson Sales Lima, C | 1 |
| Nakamura, MAM | 1 |
| Ranzani, OT | 1 |
| Goligher, EC | 1 |
| Tucci, MR | 1 |
| Ho, YL | 1 |
| Taniguchi, LU | 1 |
| Vieira, JE | 1 |
| Brochard, L | 1 |
| Amato, MBP | 1 |
| Wampole, CR | 1 |
| Smith, KE | 1 |
| German Jørgensen, JR | 1 |
| Andersen, AE | 1 |
| Vahidi, E | 1 |
| Shakoor, D | 1 |
| Aghaie Meybodi, M | 1 |
| Saeedi, M | 1 |
| Auer, J | 1 |
| Lamm, G | 1 |
| Pea, F | 1 |
| Licari, M | 1 |
| Baldassarre, M | 1 |
| Furlanut, M | 1 |
| Palencia-Herrejón, E | 1 |
| Borrallo-Pérez, JM | 1 |
| Pardo-Rey, C | 1 |
| Schröter, J | 1 |
| Wandel, C | 1 |
| Böhrer, H | 1 |
| Schmidt, H | 1 |
| Böttiger, BW | 1 |
| Martin, E | 1 |
| Maynard, ND | 2 |
| Bihari, DJ | 2 |
| Dalton, RN | 2 |
| Smithies, MN | 2 |
| Mason, RC | 2 |
| Beale, R | 1 |
| Berkenstadt, H | 1 |
| Segal, E | 1 |
| Mayan, H | 1 |
| Almog, S | 1 |
| Rotenberg, M | 1 |
| Perel, A | 1 |
| Ezra, D | 1 |
| DePietro, MR | 1 |
| Eichacker, PQ | 1 |
| Purcell, PN | 1 |
| Branson, RD | 1 |
| Schroeder, TJ | 1 |
| Davis, K | 1 |
| Johnson, DJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| High Dose Intravenous Lidocaine vs Hydromorphone for Acute Abdominal Pain in the Emergency Department: A Randomized, Comparative Efficacy Trial[NCT04398316] | Phase 4 | 187 participants (Anticipated) | Interventional | 2021-02-18 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for lidocaine and Critical Illness
| Article | Year |
|---|---|
[Intubation of the critical patient].
Topics: Anesthetics, Local; Bronchoconstriction; Clinical Competence; Critical Illness; Humans; Intubation, | 2008 |
Lidocaine for acute lung injury: questions still to answer.
Topics: Animals; Critical Illness; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Inflammatio | 2000 |
4 trials available for lidocaine and Critical Illness
| Article | Year |
|---|---|
Comparison of intravenous lidocaine versus morphine in alleviating pain in patients with critical limb ischaemia.
Topics: Administration, Intravenous; Adult; Aged; Analgesics, Opioid; Critical Illness; Double-Blind Method; | 2015 |
Lignocaine metabolite formation: an indicator for liver dysfunction and predictor of survival in surgical intensive care patients.
Topics: Aged; Bilirubin; Blood Pressure; Critical Care; Critical Illness; Female; Humans; Lidocaine; Liver; | 1995 |
Increasing splanchnic blood flow in the critically III.
Topics: Adult; Aged; Anesthetics, Local; Coloring Agents; Critical Illness; Dopamine; Dopamine Agonists; Gas | 1995 |
The pharmacokinetics of morphine and lidocaine in critically ill patients.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anti-Arrhythmia Agents; Critical Illness; Female | 1999 |
7 other studies available for lidocaine and Critical Illness
| Article | Year |
|---|---|
Phrenic Nerve Block and Respiratory Effort in Pigs and Critically Ill Patients with Acute Lung Injury.
Topics: Acute Lung Injury; Animals; Critical Illness; Disease Models, Animal; Female; Humans; Lidocaine; Phr | 2022 |
Beyond Opioids for Pain Management in Adult Critically Ill Patients.
Topics: Acetaminophen; Adrenergic alpha-2 Receptor Agonists; Adult; Analgesia; Analgesics; Analgesics, Non-N | 2019 |
[Fatal exposure to Aconitum napellus].
Topics: Aconitine; Aconitum; Anti-Arrhythmia Agents; Critical Illness; Female; Humans; Lidocaine; Middle Age | 2013 |
Drug therapy for sustained ventricular arrhythmias complicating acute myocardial infarction: What does the crystal ball tell you?
Topics: Amiodarone; Anti-Arrhythmia Agents; Critical Care; Critical Illness; Electrocardiography; Female; Hu | 2011 |
MEGX disposition in critically-ill trauma patients: subsequent assessments during the first week following trauma.
Topics: Adult; Aged; APACHE; Area Under Curve; Biomarkers; Critical Illness; Female; Half-Life; Humans; Lido | 2002 |
Liver function and splanchnic ischemia in critically ill patients.
Topics: Critical Illness; Gastric Mucosa; Hemodynamics; Humans; Hydrogen-Ion Concentration; Indocyanine Gree | 1997 |
Monoethylglycinexylidide production parallels changes in hepatic blood flow and oxygen delivery in lung injury managed with positive end-expiratory pressure.
Topics: Animals; Blood Flow Velocity; Critical Illness; Disease Models, Animal; Dogs; Evaluation Studies as | 1992 |