Page last updated: 2024-10-28

lidocaine and Costen's Syndrome

lidocaine has been researched along with Costen's Syndrome in 12 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19907 (58.33)18.7374
1990's1 (8.33)18.2507
2000's1 (8.33)29.6817
2010's3 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Uemoto, L1
Garcia, MA1
Gouvêa, CV1
Vilella, OV1
Alfaya, TA1
Handa, T1
Fukuda, K1
Ichinohe, T1
Firmani, M1
Miralles, R1
Casassus, R1
Venâncio, Rde A1
Alencar, FG1
Zamperini, C1
Weinberg, LA1
Kopp, S1
Wenneberg, B1
Zapp, JJ1
Short, S1
Grosshandler, S1
Burney, R1
Morgan, DH1
Padamsee, M1
Mehta, N1
White, GE1
Passero, PL1
Wyman, BS1
Bell, JW1
Hirschey, SA1
Schlosser, WS1
Norris, CW1
Eakins, K1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Double-blind, Prospective Comparison of Medications Used in Trigger Point Injections - Ketorolac, Lidocaine, or Dexamethasone[NCT03028012]Phase 410 participants (Actual)Interventional2017-05-02Terminated (stopped due to Poor enrollment.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants With a Responder Rate Greater Than 50% on the Numeric Rating Pain Scale (NRS) Improvement

Participants in this study underwent TPIs by the following method. The needle was inserted into the trigger point with the goal of eliciting a local twitch responses(LTRs). When a LTR was obtained, 0.1mL of randomized drug was injected into that location within the muscle. This was repeated until LTRs disappeared, or 1.0mL had been injected, whichever came first. This was performed in a similar manner for all affected muscles, up to a maximum of 2mL. Participants self-report their brief pain inventory at each of their injections (up to four subsequent injections) based off of the standardized Numeric Rating pain Scale (NRS). The NRS is nationally recognized numeric scale from zero to ten, with zero being an example of no pain, one to three would demonstrate mild pain, four to six would be moderate pain, seven to nine would be severe pain and a ten would be the worst pain possible. Improvement in BPI was determined if their NRS score went down with each injection(s). (NCT03028012)
Timeframe: Pre-Post Injections Up to Three Months

InterventionParticipants (Count of Participants)
Ketorolac1
Lidocaine0
Dexamethasone0

Brief Pain Inventory (BPI) - Modified

The BPI was evaluated on a scale from 0-10. Zero would mean no interference and 10 would be calculated at complete interferences. We used a 7-point questionnaire about pain. All scores were calculated at baseline and three months. (NCT03028012)
Timeframe: Baseline and Three Months

Interventionscore on a scale (Number)
Participant Number #3 at BaselineParticipant Number #3 at 3 MonthsParticipant Number #8 at BaselineParticipant #8 at 3 Months
Ketorolac8353

Numeric Rating Pain Scale (NRS) at Baseline and Three Months.

TPI were treated with a needle inserted into the trigger point with the goal of eliciting a local twitch responses(LTRs). When a LTR was obtained, 0.1mL of randomized drug was injected into that location within the muscle. This was repeated until LTRs disappeared, or 1.0mL had been injected, whichever came first. Such was performed in a similar manner for all affected muscles, up to a maximum of 2mL. Participants self-report their brief pain inventory at each of their injections (up to four subsequent injections) based off of the standardized Numeric Rating pain Scale (NRS). The NRS is nationally recognized numeric scale from zero to ten, with zero being an example of no pain,one to three would demonstrate mild pain, four to six would be moderate pain, seven to nine would be severe pain and a ten would be the worst pain possible. Improvement in BPI was determined if their NRS score went down with each injection(s). (NCT03028012)
Timeframe: Pre-Injection and Three Month Post Injection(s)

Interventionscore on a scale (Number)
Participant Number 3 at BaselineParticipant Number 3 at 3 MonthsParticipant Number 8 at BaselineParticipant Number 8 at 3 Months
Ketorolac8353

Trials

4 trials available for lidocaine and Costen's Syndrome

ArticleYear
Laser therapy and needling in myofascial trigger point deactivation.
    Journal of oral science, 2013, Volume: 55, Issue:2

    Topics: Adult; Anesthetics, Local; Electromyography; Female; Follow-Up Studies; Humans; Injections, Intramus

2013
Effect of lidocaine patches on upper trapezius EMG activity and pain intensity in patients with myofascial trigger points: A randomized clinical study.
    Acta odontologica Scandinavica, 2015, Volume: 73, Issue:3

    Topics: Administration, Cutaneous; Adult; Anesthetics, Local; Deglutition; Electromyography; Female; Follow-

2015
Different substances and dry-needling injections in patients with myofascial pain and headaches.
    Cranio : the journal of craniomandibular practice, 2008, Volume: 26, Issue:2

    Topics: Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Anesthetics, Local; Anti-Inflammatory Agents; Ant

2008
Effects of occlusal treatment and intraarticular injections on temporomandibular joint pain and dysfunction.
    Acta odontologica Scandinavica, 1981, Volume: 39, Issue:2

    Topics: Adult; Aged; Betamethasone; Counseling; Dental Occlusion, Balanced; Female; Humans; Injections, Intr

1981

Other Studies

8 other studies available for lidocaine and Costen's Syndrome

ArticleYear
Effect of combination of trigger point injection and stellate ganglion block on non-odontogenic mandibular molar pain referred from masseter muscle: a case report.
    The Bulletin of Tokyo Dental College, 2013, Volume: 54, Issue:3

    Topics: Adult; Anesthetics, Local; Female; Humans; Injections, Intramuscular; Lidocaine; Masseter Muscle; Ne

2013
The etiology, diagnosis, and treatment of TMJ dysfunction-pain syndrome. Part III: treatment.
    The Journal of prosthetic dentistry, 1980, Volume: 43, Issue:2

    Topics: Acrylic Resins; Biofeedback, Psychology; Dental Occlusion, Centric; Exercise Therapy; Hot Temperatur

1980
Temporomandibular joint pain as a neuropathy.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 1995, Volume: 80, Issue:6

    Topics: Administration, Oral; Drug Therapy, Combination; Facial Pain; Humans; Injections, Intravenous; Lidoc

1995
The myofascial syndrome.
    North Carolina medical journal, 1979, Volume: 40, Issue:9

    Topics: Humans; Lidocaine; Neck; Pain; Shoulder; Temporomandibular Joint Dysfunction Syndrome

1979
The great impostor. Diseases of the temporomandibular joint.
    JAMA, 1976, May-31, Volume: 235, Issue:22

    Topics: Diagnosis, Differential; Humans; Injections; Lidocaine; Methods; Temporomandibular Joint; Temporoman

1976
Trigger point injection: a neglected modality in the treatment of TMJ dysfunction.
    The Journal of pedodontics, 1987,Fall, Volume: 12, Issue:1

    Topics: Adolescent; Anesthesia, Local; Female; Humans; Injections, Intramuscular; Lidocaine; Myofascial Pain

1987
Temporomandibular joint dysfunction syndrome. A clinical report.
    Physical therapy, 1985, Volume: 65, Issue:8

    Topics: Adult; Combined Modality Therapy; Exercise Therapy; Female; Humans; Lidocaine; Male; Middle Aged; My

1985
Head and neck pain: T-M joint syndrome.
    The Laryngoscope, 1974, Volume: 84, Issue:9

    Topics: Adult; Age Factors; Aged; Diagnosis, Differential; Diazepam; Female; Head; Humans; Lidocaine; Male;

1974