lidocaine has been researched along with Complex Regional Pain Syndromes in 16 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Complex Regional Pain Syndromes: Conditions characterized by pain involving an extremity or other body region, HYPERESTHESIA, and localized autonomic dysfunction following injury to soft tissue or nerve. The pain is usually associated with ERYTHEMA; SKIN TEMPERATURE changes, abnormal sudomotor activity (i.e., changes in sweating due to altered sympathetic innervation) or edema. The degree of pain and other manifestations is out of proportion to that expected from the inciting event. Two subtypes of this condition have been described: type I; (REFLEX SYMPATHETIC DYSTROPHY) and type II; (CAUSALGIA). (From Pain 1995 Oct;63(1):127-33)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to evaluate the efficacy of guanethidine and lidocaine in the treatment of complex regional pain syndrome (CRPS) type I of the hand." | 9.12 | Treatment of complex regional pain syndrome type I of the hand with a series of intravenous regional sympathetic blocks with guanethidine and lidocaine. ( Briana, DD; Michaloglou, AA; Paraskevas, KI; Samara, M, 2006) |
| "To evaluate the efficacy of intravenous regional anesthesia (IVRA) with clonidine in patients with a previous history of complex regional pain syndrome (CRPS) who are undergoing upper extremity hand surgery." | 9.11 | Surgery on the affected upper extremity of patients with a history of complex regional pain syndrome: the use of intravenous regional anesthesia with clonidine. ( Faruqi, S; Kilaru, PA; Reuben, SS; Rosenthal, EA; Steinberg, RB, 2004) |
| "Intravenous lidocaine and diphenhydramine had no significant effect on the cool, warm, or cold pain thresholds." | 9.09 | Concentration-effect relationship of intravenous lidocaine on the allodynia of complex regional pain syndrome types I and II. ( Gerayli, A; Leung, AY; Ridgeway, BM; Wallace, MS; Yaksh, TL, 2000) |
| "The aim of this study was to evaluate the efficacy of guanethidine and lidocaine in the treatment of complex regional pain syndrome (CRPS) type I of the hand." | 5.12 | Treatment of complex regional pain syndrome type I of the hand with a series of intravenous regional sympathetic blocks with guanethidine and lidocaine. ( Briana, DD; Michaloglou, AA; Paraskevas, KI; Samara, M, 2006) |
| "To evaluate the efficacy of intravenous regional anesthesia (IVRA) with clonidine in patients with a previous history of complex regional pain syndrome (CRPS) who are undergoing upper extremity hand surgery." | 5.11 | Surgery on the affected upper extremity of patients with a history of complex regional pain syndrome: the use of intravenous regional anesthesia with clonidine. ( Faruqi, S; Kilaru, PA; Reuben, SS; Rosenthal, EA; Steinberg, RB, 2004) |
| "Intravenous lidocaine and diphenhydramine had no significant effect on the cool, warm, or cold pain thresholds." | 5.09 | Concentration-effect relationship of intravenous lidocaine on the allodynia of complex regional pain syndrome types I and II. ( Gerayli, A; Leung, AY; Ridgeway, BM; Wallace, MS; Yaksh, TL, 2000) |
| " We prospectively evaluated the use of four anesthetic techniques (general anesthesia, axillary block, and IV regional anesthesia [IVRA] with lidocaine with or without clonidine) for patients undergoing fasciectomy for Dupuytren's contracture." | 3.73 | The incidence of complex regional pain syndrome after fasciectomy for Dupuytren's contracture: a prospective observational study of four anesthetic techniques. ( Dixon, D; Faruqi, S; Madabhushi, L; Pristas, R; Reuben, SS; Wenner, S, 2006) |
| "IV lidocaine did not produce significant changes in spontaneous and evoked pain intensity measurements compared to pretreatment values." | 2.74 | Lumbar sympathetic blockade in children with complex regional pain syndromes: a double blind placebo-controlled crossover trial. ( Berde, CB; Meier, PM; Sethna, NF; Zurakowski, D, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (56.25) | 29.6817 |
| 2010's | 5 (31.25) | 24.3611 |
| 2020's | 2 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Fallico, N | 1 |
| Padmanabhan, R | 1 |
| Rahman, S | 1 |
| Somma, F | 1 |
| Spagnoli, AM | 1 |
| Henderson, J | 1 |
| Qureshi, AA | 1 |
| Friedman, AJ | 1 |
| Carcamo, CR | 1 |
| Palumbo, A | 1 |
| Toomay, S | 1 |
| Singh, K | 1 |
| Kalva, S | 1 |
| Schwartzman, RJ | 1 |
| Patel, M | 1 |
| Grothusen, JR | 1 |
| Alexander, GM | 1 |
| Meier, PM | 1 |
| Zurakowski, D | 1 |
| Berde, CB | 1 |
| Sethna, NF | 1 |
| Becker, BE | 1 |
| Jones, JD | 1 |
| Albert, DA | 1 |
| Thadani, V | 1 |
| Rigby, WF | 1 |
| Nixdorf, DR | 1 |
| Sobieh, R | 1 |
| Gierthmühlen, J | 1 |
| Reuben, SS | 2 |
| Rosenthal, EA | 1 |
| Steinberg, RB | 1 |
| Faruqi, S | 2 |
| Kilaru, PA | 1 |
| Paraskevas, KI | 2 |
| Michaloglou, AA | 1 |
| Briana, DD | 1 |
| Samara, M | 1 |
| Pristas, R | 1 |
| Dixon, D | 1 |
| Madabhushi, L | 1 |
| Wenner, S | 1 |
| Chen, LC | 1 |
| Wong, CS | 1 |
| Huh, BK | 1 |
| Huang, YS | 1 |
| Yang, CP | 1 |
| Yeh, CC | 1 |
| Wu, CT | 1 |
| Wallace, MS | 1 |
| Ridgeway, BM | 1 |
| Leung, AY | 1 |
| Gerayli, A | 1 |
| Yaksh, TL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Physical and Psychological Changes in Complex Regional Pain Syndrome (CRPS) Patients Undergoing Multimodal Rehabilitation[NCT05696587] | 42 participants (Actual) | Interventional | 2021-10-10 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 trials available for lidocaine and Complex Regional Pain Syndromes
| Article | Year |
|---|---|
A randomised placebo-controlled clinical trial on the efficacy of local lidocaine injections and oral citalopram for the treatment of complex regional pain syndrome.
Topics: Anesthetics, Local; Citalopram; Complex Regional Pain Syndromes; Double-Blind Method; Humans; Lidoca | 2022 |
Commentary on: A randomised placebo-controlled clinical trial on the efficacy of local lidocaine injections and oral citalopram for the treatment of complex regional pain syndrome.
Topics: Anesthetics, Local; Citalopram; Complex Regional Pain Syndromes; Double-Blind Method; Humans; Lidoca | 2022 |
Lumbar sympathetic blockade in children with complex regional pain syndromes: a double blind placebo-controlled crossover trial.
Topics: Adolescent; Anesthesia, General; Anesthetics, Local; Autonomic Nerve Block; Catheterization; Child; | 2009 |
Surgery on the affected upper extremity of patients with a history of complex regional pain syndrome: the use of intravenous regional anesthesia with clonidine.
Topics: Anesthesia, Conduction; Anesthetics, Combined; Anesthetics, Intravenous; Clonidine; Complex Regional | 2004 |
Treatment of complex regional pain syndrome type I of the hand with a series of intravenous regional sympathetic blocks with guanethidine and lidocaine.
Topics: Adult; Aged; Anesthetics, Local; Autonomic Nerve Block; Complex Regional Pain Syndromes; Drug Therap | 2006 |
Concentration-effect relationship of intravenous lidocaine on the allodynia of complex regional pain syndrome types I and II.
Topics: Adult; Aged; Anesthetics, Local; Blood Pressure; Cold Temperature; Complex Regional Pain Syndromes; | 2000 |
10 other studies available for lidocaine and Complex Regional Pain Syndromes
| Article | Year |
|---|---|
Complex Regional Pain Syndrome: What the Dermatologist Should Know.
Topics: Administration, Cutaneous; Complex Regional Pain Syndromes; Diagnosis, Differential; Female; Humans; | 2018 |
Dysarthria Associated with Lumbar Sympathetic Block Using Botulinum Toxin.
Topics: Adult; Anesthetics, Local; Ankle Fractures; Autonomic Nerve Block; Botulinum Toxins, Type A; Botulis | 2019 |
Angiography in Complex Regional Pain Syndrome.
Topics: Amines; Analgesics; Anesthetics, Local; Angiography; Complex Regional Pain Syndromes; Cyclohexanecar | 2017 |
Efficacy of 5-day continuous lidocaine infusion for the treatment of refractory complex regional pain syndrome.
Topics: Adolescent; Adult; Anesthetics, Local; Child; Complex Regional Pain Syndromes; Female; Humans; Infus | 2009 |
Re: use of regional blockade to facilitate inpatient rehabilitation of recalcitrant complex regional pain syndrome.
Topics: Anesthesia, Conduction; Anesthetics, Local; Complex Regional Pain Syndromes; Humans; Infusions, Pare | 2009 |
Unusual case of a swollen painful toe in a young man.
Topics: Acne Vulgaris; Adult; Amines; Analgesics, Opioid; Anti-Bacterial Agents; Arthritis; Complex Regional | 2012 |
Using an n-of-1 trial to assist in clinical decision making for patients with orofacial pain.
Topics: Adult; Complex Regional Pain Syndromes; Decision Support Techniques; Double-Blind Method; Facial Pai | 2012 |
The incidence of complex regional pain syndrome after fasciectomy for Dupuytren's contracture: a prospective observational study of four anesthetic techniques.
Topics: Aged; Anesthesia; Anesthesia, Conduction; Anesthesia, General; Anesthesia, Intravenous; Arm; Axilla; | 2006 |
Repeated lumbar sympathetic blockade with lidocaine and clonidine attenuates pain in complex regional pain syndrome type 1 patients--a report of two cases.
Topics: Adult; Autonomic Nerve Block; Clonidine; Complex Regional Pain Syndromes; Humans; Lidocaine; Lumbosa | 2006 |
Complex regional pain syndrome-a multifaceted disorder requiring multidimensional care: case study.
Topics: Analgesics; Anesthetics, Local; Autonomic Nerve Block; Complex Regional Pain Syndromes; Guanethidine | 2008 |