lidocaine has been researched along with Colorectal Cancer in 12 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Local anesthetics, especially lidocaine, have been intensively studied in relation with postoperative outcome in colorectal cancer patients." | 9.69 | The Influence of Intravenous Lidocaine Infusion on Postoperative Outcome and Neutrophil-to-Lymphocyte Ratio in Colorectal Cancer Patients. A Pilot Study. ( Al Hajjar, N; Alexa, AL; Breazu, C; Ciocan, A; Ionescu, D; Sargarovschi, S; Valean, D; Zaharie, F, 2023) |
| "gov designed to compare the effects of two different anesthetic techniques added perioperative intravenous lidocaine infusion on long-term outcomes exclusively in colorectal cancer patients undergoing surgery." | 9.51 | The influence of TIVA or inhalation anesthesia with or without intravenous lidocaine on postoperative outcome in colorectal cancer surgery: a study protocol for a prospective clinical study. ( Alexa, AL; Ionescu, D; Tat, TF, 2022) |
| "Topical lidocaine is an effective and safe method for suppressing colorectal spasm during colonoscopy (UMIN000024733)." | 9.30 | Inhibitory effect of lidocaine on colonic spasm during colonoscopy: A multicenter double-blind, randomized controlled trial. ( Aizawa, M; Fujita, T; Hewett, DG; Iwaki, T; Katsuki, S; Matsuda, T; Mori, H; Nemoto, D; Suzuki, S; Takeuchi, Y; Togashi, K; Uraoka, T, 2019) |
| "PubMed, Embase, Web of Science, CNKI, SinoMed and WanFang Data databases were electronically retrieved to include the randomised controlled trials comparing perioperative intravenous lidocaine with placebo infusion in patients undergoing resection of colorectal cancer before August 2021." | 8.02 | Effect of perioperative intravenous lidocaine on postoperative outcomes in patients undergoing resection of colorectal cancer: a protocol for systematic review and meta-analysis. ( Bian, J; Bo, L; Ji, W; Liu, J; Sun, G; Wang, X; Zhang, X, 2021) |
| "Lidocaine is a conventional local anesthetic which is shown antiproliferative of colorectal cancer (CRC) in patients." | 7.88 | Lidocaine inhibits proliferation and induces apoptosis in colorectal cancer cells by upregulating mir-520a-3p and targeting EGFR. ( Qu, X; Shi, Q; Wang, D; Wang, X; Wu, G; Yang, L, 2018) |
| " Local anesthetics, especially lidocaine, have been intensively studied in relation with postoperative outcome in colorectal cancer patients." | 5.69 | The Influence of Intravenous Lidocaine Infusion on Postoperative Outcome and Neutrophil-to-Lymphocyte Ratio in Colorectal Cancer Patients. A Pilot Study. ( Al Hajjar, N; Alexa, AL; Breazu, C; Ciocan, A; Ionescu, D; Sargarovschi, S; Valean, D; Zaharie, F, 2023) |
| " Intravenous lidocaine can reduce perioperative inflammatory response in patients undergoing laparoscopic surgery, while the effect of intraoperative intravenous lidocaine on postoperative cognitive function in patients undergoing laparoscopic colorectal cancer surgery has not been well studied." | 5.69 | Intravenous lidocaine improves postoperative cognition in patients undergoing laparoscopic colorectal surgery: a randomized, double-blind, controlled study. ( Dai, J; Deng, HW; Guo, HJ; He, GF; Li, YL; Liu, Y; Wang, Q; Wang, XX, 2023) |
| "gov designed to compare the effects of two different anesthetic techniques added perioperative intravenous lidocaine infusion on long-term outcomes exclusively in colorectal cancer patients undergoing surgery." | 5.51 | The influence of TIVA or inhalation anesthesia with or without intravenous lidocaine on postoperative outcome in colorectal cancer surgery: a study protocol for a prospective clinical study. ( Alexa, AL; Ionescu, D; Tat, TF, 2022) |
| "Topical lidocaine is an effective and safe method for suppressing colorectal spasm during colonoscopy (UMIN000024733)." | 5.30 | Inhibitory effect of lidocaine on colonic spasm during colonoscopy: A multicenter double-blind, randomized controlled trial. ( Aizawa, M; Fujita, T; Hewett, DG; Iwaki, T; Katsuki, S; Matsuda, T; Mori, H; Nemoto, D; Suzuki, S; Takeuchi, Y; Togashi, K; Uraoka, T, 2019) |
| "PubMed, Embase, Web of Science, CNKI, SinoMed and WanFang Data databases were electronically retrieved to include the randomised controlled trials comparing perioperative intravenous lidocaine with placebo infusion in patients undergoing resection of colorectal cancer before August 2021." | 4.02 | Effect of perioperative intravenous lidocaine on postoperative outcomes in patients undergoing resection of colorectal cancer: a protocol for systematic review and meta-analysis. ( Bian, J; Bo, L; Ji, W; Liu, J; Sun, G; Wang, X; Zhang, X, 2021) |
| "Lidocaine is a conventional local anesthetic which is shown antiproliferative of colorectal cancer (CRC) in patients." | 3.88 | Lidocaine inhibits proliferation and induces apoptosis in colorectal cancer cells by upregulating mir-520a-3p and targeting EGFR. ( Qu, X; Shi, Q; Wang, D; Wang, X; Wu, G; Yang, L, 2018) |
| "Lidocaine or saline was sprayed on the colonic mucosa within 5 cm above and below the polyps before polypectomy." | 1.91 | Intestinal topical lidocaine spray improves the efficacy and safety of endoscopic sigmoid polypectomy. ( Lin, DY; Liu, WH; Lu, Q; Wang, XY; Xiong, F; Zeng, T, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 8 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, H | 1 |
| Zhang, X | 2 |
| Li, Y | 2 |
| Pang, T | 1 |
| Alexa, AL | 2 |
| Tat, TF | 1 |
| Ionescu, D | 2 |
| Karlsdottir, BR | 1 |
| Zhou, PP | 1 |
| Wahba, J | 1 |
| Mott, SL | 1 |
| Goffredo, P | 1 |
| Hrabe, J | 1 |
| Hassan, I | 1 |
| Kapadia, MR | 1 |
| Gribovskaja-Rupp, I | 1 |
| Ciocan, A | 1 |
| Zaharie, F | 1 |
| Valean, D | 1 |
| Sargarovschi, S | 1 |
| Breazu, C | 1 |
| Al Hajjar, N | 1 |
| Lu, Q | 1 |
| Xiong, F | 1 |
| Wang, XY | 1 |
| Zeng, T | 1 |
| Lin, DY | 1 |
| Liu, WH | 1 |
| Wang, XX | 1 |
| Dai, J | 1 |
| Wang, Q | 1 |
| Deng, HW | 1 |
| Liu, Y | 1 |
| He, GF | 1 |
| Guo, HJ | 1 |
| Li, YL | 1 |
| Ijiri, M | 1 |
| Sasaki, T | 1 |
| Fujiya, M | 1 |
| Iwama, T | 1 |
| Murakami, Y | 1 |
| Takahashi, K | 1 |
| Tanaka, K | 1 |
| Ando, K | 1 |
| Ueno, N | 1 |
| Kashima, S | 1 |
| Moriichi, K | 1 |
| Tanabe, H | 1 |
| Saito, Y | 1 |
| Okumura, T | 1 |
| Ji, W | 1 |
| Sun, G | 1 |
| Wang, X | 2 |
| Liu, J | 1 |
| Bian, J | 1 |
| Bo, L | 1 |
| Bazin, P | 1 |
| Padley, J | 1 |
| Ho, M | 1 |
| Stevens, J | 1 |
| Ben-Menachem, E | 1 |
| Nemoto, D | 1 |
| Suzuki, S | 1 |
| Mori, H | 1 |
| Katsuki, S | 1 |
| Iwaki, T | 1 |
| Aizawa, M | 1 |
| Takeuchi, Y | 1 |
| Uraoka, T | 1 |
| Matsuda, T | 1 |
| Fujita, T | 1 |
| Hewett, DG | 1 |
| Togashi, K | 1 |
| Qu, X | 1 |
| Yang, L | 1 |
| Shi, Q | 1 |
| Wang, D | 1 |
| Wu, G | 1 |
| Lee, MW | 1 |
| Or, DY | 1 |
| Tsang, AC | 1 |
| Ng, DC | 1 |
| Chen, PP | 1 |
| Cheung, MH | 1 |
| Li, RS | 1 |
| Leong, HT | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Influence of Anesthesia on Postoperative Outcome and Complications in Colorectal Cancer Patients[NCT02786329] | Early Phase 1 | 450 participants (Anticipated) | Interventional | 2016-06-30 | Recruiting | ||
| Intravenous Lignocaine as an Analgesic Adjunct in Adolescent Idiopathic Scoliosis Surgery (IGNITE-AIS Study)[NCT04931433] | Phase 4 | 102 participants (Anticipated) | Interventional | 2020-12-24 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 trials available for lidocaine and Colorectal Cancer
| Article | Year |
|---|---|
The influence of TIVA or inhalation anesthesia with or without intravenous lidocaine on postoperative outcome in colorectal cancer surgery: a study protocol for a prospective clinical study.
Topics: Administration, Intravenous; Anesthesia, Inhalation; Colorectal Neoplasms; Humans; Lidocaine; Neopla | 2022 |
The Influence of Intravenous Lidocaine Infusion on Postoperative Outcome and Neutrophil-to-Lymphocyte Ratio in Colorectal Cancer Patients. A Pilot Study.
Topics: Anesthetics, Local; Colorectal Neoplasms; Double-Blind Method; Humans; Infusions, Intravenous; Lidoc | 2023 |
Intravenous lidocaine improves postoperative cognition in patients undergoing laparoscopic colorectal surgery: a randomized, double-blind, controlled study.
Topics: Anesthetics, Local; Cognition; Colorectal Neoplasms; Colorectal Surgery; Double-Blind Method; Humans | 2023 |
The efficacy of the submucosal injection of lidocaine during endoscopic submucosal dissection for colorectal neoplasms: a multicenter randomized controlled study.
Topics: Colorectal Neoplasms; Dissection; Endoscopic Mucosal Resection; Humans; Lidocaine; Prospective Studi | 2021 |
The effect of intravenous lidocaine infusion on bispectral index during major abdominal surgery.
Topics: Abdomen; Aged; Anesthesia, General; Anesthetics; Anesthetics, Intravenous; Colorectal Neoplasms; Ele | 2018 |
Inhibitory effect of lidocaine on colonic spasm during colonoscopy: A multicenter double-blind, randomized controlled trial.
Topics: Administration, Topical; Adult; Aged; Anesthetics, Local; Colonoscopy; Colorectal Neoplasms; Double- | 2019 |
6 other studies available for lidocaine and Colorectal Cancer
| Article | Year |
|---|---|
Lidocaine hampers colorectal cancer process via circITFG2/miR-1204/SOCS2 axis.
Topics: Cell Line, Tumor; Colorectal Neoplasms; Humans; Lidocaine; MicroRNAs; RNA, Circular; Suppressor of C | 2022 |
Male gender, smoking, younger age, and preoperative pain found to increase postoperative opioid requirements in 592 elective colorectal resections.
Topics: Abdominal Pain; Aged; Analgesics, Opioid; Colorectal Neoplasms; Female; Humans; Lidocaine; Male; Mid | 2022 |
Intestinal topical lidocaine spray improves the efficacy and safety of endoscopic sigmoid polypectomy.
Topics: Colonic Polyps; Colonoscopy; Colorectal Neoplasms; Endoscopic Mucosal Resection; Humans; Lidocaine; | 2023 |
Effect of perioperative intravenous lidocaine on postoperative outcomes in patients undergoing resection of colorectal cancer: a protocol for systematic review and meta-analysis.
Topics: Anesthetics, Local; Colorectal Neoplasms; Humans; Lidocaine; Meta-Analysis as Topic; Systematic Revi | 2021 |
Lidocaine inhibits proliferation and induces apoptosis in colorectal cancer cells by upregulating mir-520a-3p and targeting EGFR.
Topics: Anesthetics, Local; Apoptosis; Cell Proliferation; Colorectal Neoplasms; ErbB Receptors; Gene Expres | 2018 |
Intravenous lignocaine infusion facilitates acute rehabilitation after laparoscopic colectomy in the Chinese patients.
Topics: Aged; Anesthetics, Local; Colectomy; Colorectal Neoplasms; Female; Humans; Infusions, Intravenous; L | 2017 |