lidocaine and Colonic Neoplasms studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Research Excerpts

Excerpt	Relevance	Reference
" lidocaine were able to decrease postoperative pain and duration of ileus."	5.12	Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery. ( Chen, KM; Jao, SW; Kuo, CP; Sheen, MJ; Wong, CS; Wu, CT; Yeh, CC, 2006)
"Sixty four patients with colon cancer scheduled for elective colon resection were involved in this study."	2.79	Intravenous lidocaine for post-operative pain relief after hand-assisted laparoscopic colon surgery: a randomized, placebo-controlled clinical trial. ( Miliauskas, P; Samalavičius, NE; Samalavičius, R; Tikuišis, R; Zabulis, V; Žurauskas, A, 2014)
"Metastatic breast and colon cancer cells express neonatal and adult splice variants of NaV1."	1.40	Potent inhibition by ropivacaine of metastatic colon cancer SW620 cell invasion and NaV1.5 channel function. ( Baptista-Hon, DT; Hales, TG; Lee, NH; Lydon, EL; Owen, SJ; Robertson, FM; Robertson, GB; Rogers, GW, 2014)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (18.18)	18.7374
1990's	2 (18.18)	18.2507
2000's	3 (27.27)	29.6817
2010's	3 (27.27)	24.3611
2020's	1 (9.09)	2.80

Authors	Studies
Habago, SD	1
Ordodi, V	1
Bojin, F	1
Vesa, SC	1
Moldovan, V	1
Paunescu, V	1
Ionescu, D	1
Bundscherer, AC	1
Malsy, M	1
Bitzinger, DI	1
Wiese, CH	1
Gruber, MA	1
Graf, BM	1
Tikuišis, R	1
Miliauskas, P	1
Samalavičius, NE	1
Žurauskas, A	1
Samalavičius, R	1
Zabulis, V	1
Baptista-Hon, DT	1
Robertson, FM	1
Robertson, GB	1
Owen, SJ	1
Rogers, GW	1
Lydon, EL	1
Lee, NH	1
Hales, TG	1
Kakinohana, M	1
Nakamura, S	1
Miyata, Y	1
Sugahara, K	1
Kuo, CP	1
Jao, SW	1
Chen, KM	1
Wong, CS	1
Yeh, CC	1
Sheen, MJ	1
Wu, CT	1
Lahav, M	1
Levite, M	1
Bassani, L	1
Lang, A	1
Fidder, H	1
Tal, R	1
Bar-Meir, S	1
Mayer, L	1
Chowers, Y	1
Kratzer, GL	1
Illek, B	2
Fischer, H	2
Kreusel, KM	1
Hegel, U	1
Clauss, W	1
Machen, TE	1
Dorogan', DA	1
Rudenko, VE	1
Pravosudivich, SA	1
Vol'pova, SM	1

Trial	Phase	Enrollment	Study Type	Start Date	Status
Effectivness of Tramadol or Topic Lidocaine on Postoperative Analgesia in Laparoscopic Colorectal Resection.[NCT05831761]		83 participants (Actual)	Interventional	2009-09-01	Completed
Intravenous Lidocaine Infusion in the Management of Post-operative Pain in Colorectal Patients[NCT01836614]	Phase 1/Phase 2	0 participants (Actual)	Interventional	2015-01-31	Withdrawn (stopped due to Study was closed due to recommendations of performing a PK study first.)
Intravenous Lidocaine for Perioperative and Postoperative Analgesia[NCT03921567]	Phase 4	520 participants (Anticipated)	Interventional	2019-04-15	Recruiting
Perioperative Protective Effects of Lidocaine - Clinical Study on the Route and Timing of Administration[NCT00413127]	Phase 2/Phase 3	78 participants (Actual)	Interventional	2007-09-30	Terminated (stopped due to Less patients than expected for inclusion, therefore patient recruitment is to low)
Intravenous Lidocaine for Postoperative Recovery in Liver Surgery, a Randomized Double Blinded Placebo-controlled Study[NCT05153785]	Phase 2/Phase 3	80 participants (Anticipated)	Interventional	2021-11-15	Recruiting
Effect of Intravenous Lignocaine Infusion on Intraoperative End Tidal Desflurane Concentration Requirements: A Randomised Double-Blinded Controlled Study[NCT06064331]		48 participants (Actual)	Interventional	2021-01-21	Completed
Pharmacokinetics of Intravenous Lidocaine Infusion in Children[NCT02241096]	Phase 1	2 participants (Actual)	Interventional	2015-01-31	Terminated (stopped due to Lack of available study participants.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Article	Year
Intravenous lidocaine for post-operative pain relief after hand-assisted laparoscopic colon surgery: a randomized, placebo-controlled clinical trial. Techniques in coloproctology, 2014, Volume: 18, Issue:4 Topics: Adolescent; Adult; Anesthetics, Local; Colon; Colonic Neoplasms; Double-Blind Method; Female; Hand-A	2014
Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery. British journal of anaesthesia, 2006, Volume: 97, Issue:5 Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Ane	2006
Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery. British journal of anaesthesia, 2006, Volume: 97, Issue:5 Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Ane	2006
Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery. British journal of anaesthesia, 2006, Volume: 97, Issue:5 Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Ane	2006
Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery. British journal of anaesthesia, 2006, Volume: 97, Issue:5 Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Ane	2006
Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery. British journal of anaesthesia, 2006, Volume: 97, Issue:5 Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Ane	2006
Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery. British journal of anaesthesia, 2006, Volume: 97, Issue:5 Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Ane	2006
Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery. British journal of anaesthesia, 2006, Volume: 97, Issue:5 Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Ane	2006
Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery. British journal of anaesthesia, 2006, Volume: 97, Issue:5 Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Ane	2006
Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery. British journal of anaesthesia, 2006, Volume: 97, Issue:5 Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Ane	2006
Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery. British journal of anaesthesia, 2006, Volume: 97, Issue:5 Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Ane	2006
Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery. British journal of anaesthesia, 2006, Volume: 97, Issue:5 Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Ane	2006
Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery. British journal of anaesthesia, 2006, Volume: 97, Issue:5 Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Ane	2006
Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery. British journal of anaesthesia, 2006, Volume: 97, Issue:5 Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Ane	2006
Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery. British journal of anaesthesia, 2006, Volume: 97, Issue:5 Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Ane	2006
Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery. British journal of anaesthesia, 2006, Volume: 97, Issue:5 Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Ane	2006
Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery. British journal of anaesthesia, 2006, Volume: 97, Issue:5 Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Ane	2006
Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery. British journal of anaesthesia, 2006, Volume: 97, Issue:5 Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Ane	2006
Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery. British journal of anaesthesia, 2006, Volume: 97, Issue:5 Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Ane	2006
Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery. British journal of anaesthesia, 2006, Volume: 97, Issue:5 Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Ane	2006
Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery. British journal of anaesthesia, 2006, Volume: 97, Issue:5 Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Ane	2006
Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery. British journal of anaesthesia, 2006, Volume: 97, Issue:5 Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Ane	2006
Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery. British journal of anaesthesia, 2006, Volume: 97, Issue:5 Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Ane	2006
Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery. British journal of anaesthesia, 2006, Volume: 97, Issue:5 Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Ane	2006
Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery. British journal of anaesthesia, 2006, Volume: 97, Issue:5 Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Ane	2006
Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery. British journal of anaesthesia, 2006, Volume: 97, Issue:5 Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Ane	2006
Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery. British journal of anaesthesia, 2006, Volume: 97, Issue:5 Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Ane	2006
Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery. British journal of anaesthesia, 2006, Volume: 97, Issue:5 Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Ane	2006
Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery. British journal of anaesthesia, 2006, Volume: 97, Issue:5 Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Ane	2006
Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery. British journal of anaesthesia, 2006, Volume: 97, Issue:5 Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Ane	2006
Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery. British journal of anaesthesia, 2006, Volume: 97, Issue:5 Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Ane	2006
Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery. British journal of anaesthesia, 2006, Volume: 97, Issue:5 Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Ane	2006
Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery. British journal of anaesthesia, 2006, Volume: 97, Issue:5 Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Ane	2006
Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery. British journal of anaesthesia, 2006, Volume: 97, Issue:5 Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Ane	2006
Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery. British journal of anaesthesia, 2006, Volume: 97, Issue:5 Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Ane	2006
Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery. British journal of anaesthesia, 2006, Volume: 97, Issue:5 Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Ane	2006
Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery. British journal of anaesthesia, 2006, Volume: 97, Issue:5 Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Ane	2006

Article	Year
Inhibitory effects of lidocaine on colon carcinoma progression in a rat model: a pilot study. British journal of anaesthesia, 2023, Volume: 131, Issue:5 Topics: Anesthetics, Local; Animals; Carcinoma; Colonic Neoplasms; Lidocaine; Pilot Projects; Rats	2023
Effects of Lidocaine on HT-29 and SW480 Colon Cancer Cells Anticancer research, 2017, Volume: 37, Issue:4 Topics: Anti-Arrhythmia Agents; Apoptosis; Cell Cycle; Cell Proliferation; Colonic Neoplasms; Enzyme-Linked	2017
Potent inhibition by ropivacaine of metastatic colon cancer SW620 cell invasion and NaV1.5 channel function. British journal of anaesthesia, 2014, Volume: 113 Suppl 1 Topics: Adult; Age Factors; Amides; Anesthetics, Local; Cell Movement; Collagen; Colonic Neoplasms; Dose-Res	2014
Emergence from propofol anesthesia in a nonagenarian at a Bispectral Index of 52. Anesthesia and analgesia, 2005, Volume: 101, Issue:1 Topics: Aged; Aged, 80 and over; Anesthesia Recovery Period; Anesthesia, Epidural; Anesthesia, Intravenous;	2005
Lidocaine inhibits secretion of IL-8 and IL-1beta and stimulates secretion of IL-1 receptor antagonist by epithelial cells. Clinical and experimental immunology, 2002, Volume: 127, Issue:2 Topics: Adenocarcinoma; Anesthetics, Local; Bupivacaine; Colitis, Ulcerative; Colonic Neoplasms; Epithelial	2002
Outpatient anorectal surgery. American family physician, 1975, Volume: 11, Issue:3 Topics: Abscess; Ambulatory Care; Anal Canal; Anesthesia, Local; Anus Diseases; Bandages; Cathartics; Coloni	1975
Volume-sensitive basolateral K+ channels in HT-29/B6 cells: block by lidocaine, quinidine, NPPB, and Ba2+. The American journal of physiology, 1992, Volume: 263, Issue:3 Pt 1 Topics: Adenocarcinoma; Animals; Barium; Cell Membrane Permeability; Chlorides; Colonic Neoplasms; Electroph	1992
Intracellular Ca2+ signalling is modulated by K+ channel blockers in colonic epithelial cells (HT-29/B6). Pflugers Archiv : European journal of physiology, 1992, Volume: 422, Issue:1 Topics: Atropine; Calcium; Carbachol; Colonic Neoplasms; Epithelial Cells; Epithelium; Humans; Intracellular	1992
[Use of long-term epidural anesthesia in cancer of the colon and rectum]. Vestnik khirurgii imeni I. I. Grekova, 1988, Volume: 141, Issue:12 Topics: Adjuvants, Anesthesia; Adult; Aged; Anesthesia, Epidural; Colectomy; Colonic Neoplasms; Colostomy; H	1988

lidocaine and Colonic Neoplasms

Research Excerpts

Research

Studies (11)

Authors

Clinical Trials (7)

Trial Overview

Trials

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