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lidocaine and Chronic Illness

lidocaine has been researched along with Chronic Illness in 216 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Research Excerpts

ExcerptRelevanceReference
"Polidocanol injections have been used to treat chronic Achilles tendinopathy in clinical settings, but the few studies published show inconsistent results."9.27No beneficial effect of Polidocanol treatment in Achilles tendinopathy: a randomised controlled trial. ( Ebbesen, BH; Gregersen, HE; Mølgaard, CM; Olesen, JL; Simonsen, O, 2018)
"To determine the effectiveness of aerosolised carcainium chloride (VRP700) in controlling cough in patients with IIP."9.22Antitussive effect of carcainium chloride in patients with chronic cough and idiopathic interstitial pneumonias: A pilot study. ( Fontana, GA; Franciosi, L; Lavorini, F; Page, CP; Spina, D; Walker, MJ, 2016)
"Intravenous perioperative lidocaine decreases the incidence and severity of PPSP after breast cancer surgery."9.16Perioperative intravenous lidocaine decreases the incidence of persistent pain after breast surgery. ( Grigoras, A; Lee, P; Sattar, F; Shorten, G, 2012)
"Our study clearly demonstrates that the therapeutic use of topical nifedipine and lidocaine ointment should be extended to the conservative treatment of chronic anal fissure."9.10Topical nifedipine with lidocaine ointment vs. active control for treatment of chronic anal fissure: results of a prospective, randomized, double-blind study. ( Antropoli, C; Antropoli, M; Attena, F; Balzano, A; Bove, A; De Stefano, G; Molino, D; Perrotti, P, 2002)
"To assess the effectiveness and safety of the lidocaine patch 5%, a targeted peripheral analgesic, in the treatment of postherpetic neuralgia, painful diabetic neuropathy, and low back pain patients with incomplete responses to their current analgesic treatment regimen containing gabapentin."9.10Lidocaine patch 5% with systemic analgesics such as gabapentin: a rational polypharmacy approach for the treatment of chronic pain. ( Drass, M; Nalamachu, S; Patel, N; White, WT, 2003)
"Although the lignocaine (lidocaine)-prilocaine cream EMLA has been extensively studied for the relief of acute treatment-related pain from sharp leg ulcer debridement, no data exist on systemic absorption from prolonged application in patients with chronically painful ulcers."9.09Plasma concentrations of lignocaine and prilocaine after a 24-h application of analgesic cream (EMLA) to leg ulcers. ( Lillieborg, S; Stymne, B, 2001)
"To assess the efficacy of 4% topical lidocaine in spheno-palatine blocks, a randomized controlled trial was carried out on patients with chronic muscle pain syndromes."9.08The use of topical 4% lidocaine in spheno-palatine ganglion blocks for the treatment of chronic muscle pain syndromes: a randomized, controlled trial. ( Delaney, G; Heck, C; Janzen, V; McCain, GA; Russell, AL; Scudds, RA; Teasell, RW; Varkey, G; Woodbury, GM, 1995)
"Topical application of nitroglycerine represents a new, easily handled, and effective alternative in the treatment of anal fissures."9.08Local nitroglycerin for treatment of anal fissures: an alternative to lateral sphincterotomy? ( Bacher, H; Cerwenka, H; El-Shabrawi, A; Mischinger, HJ; Pfeifer, J; Schweiger, W; Werkgartner, G, 1997)
"To evaluate the efficacy of continuous administration of 50% nitrous oxide in oxygen for reducing pain during flexible fiberoptic bronchoscopy 32 children aged 3-60 months were randomly assigned to an experimental or a control group."9.08[Bronchial endoscopy under local anesthesia and pain in children. The value of a nitrous oxide-oxygen combination]. ( Dupont, D; Garcia, J; Hayem, C; Roure, P, 1998)
"Twenty patients with chronic pain who previously had obtained analgesia from epidural clonidine and lignocaine agreed to participate in a double-blind crossover study of lumbar epidural clonidine (150 micrograms), lignocaine (40 mg) and the combination of clonidine (150 microgram) and lignocaine (40 mg), all drugs were given in a volume of 3 ml."9.08A double-blind randomised comparison of the effects of epidural clonidine, lignocaine and the combination of clonidine and lignocaine in patients with chronic pain. ( Glynn, C; O'Sullivan, K, 1996)
"In a randomized double-blind, cross-over study the effect of intravenous lidocaine (5 mg/kg body weight) on the symptoms and signs of painful diabetic neuropathy of more than 6 months duration has been evaluated."9.06Intravenous lidocaine infusion--a new treatment of chronic painful diabetic neuropathy? ( Angelo, HR; Dejgård, A; Hilsted, J; Kastrup, J; Petersen, P, 1987)
"The efficacy and safety of intravenous tocainide were compared with intravenous lidocaine in patients with chronic ventricular arrhythmias in a double-blind, parallel study."9.06Double-blind randomized comparison of intravenous tocainide versus lidocaine in the treatment of chronic ventricular arrhythmias. ( Butler, ML; Esterbrooks, D; Hilleman, DE; Mohiuddin, SM; Mooss, AN; Sketch, MH; Stengel, LA, 1987)
"The long-term safety of patient-administered nebulized lidocaine for control of chronic cough has not been established."7.79Long-term safety of nebulized lidocaine for adults with difficult-to-control chronic cough: a case series. ( Hahn, PY; Keogh, KA; Lim, KG; Morgenthaler, TI; Olson, EJ; Rank, MA, 2013)
"The present study investigated the effects of different doses of intrathecal lidocaine on established thermal hyperalgesia and tactile allodynia in the chronic constriction injury model of neuropathic pain, defined the effective drug dose range, the duration of pain-relief effects, and the influence of this treatment on the body and tissues."7.75Effects of intrathecal lidocaine on hyperalgesia and allodynia following chronic constriction injury in rats. ( Gu, Y; Su, D; Tian, J; Wang, X; Wu, Y, 2009)
"The proportion of chronic pain patients with suspected neuropathic pain who will have clinically meaningful pain relief with intravenous (IV) lidocaine and the clinical characteristics that identify these patients have not been described previously."7.74Multivariate analysis of chronic pain patients undergoing lidocaine infusions: increasing pain severity and advancing age predict likelihood of clinically meaningful analgesia. ( Carroll, I; Gaeta, R; Mackey, S, 2007)
" Three studies are presented that provide preliminary evidence for the utility of the NPS for characterizing distinct pain qualities and changes in pain qualities in patients treated with the lidocaine patch 5% for a variety of neuropathic and non-neuropathic chronic pain conditions, including low-back pain, osteoarthritis, post-herpetic neuralgia, and painful diabetic neuropathy."7.72Introduction: chronic pain studies of the lidocaine patch 5% using the Neuropathic Pain Scale. ( Jensen, MP, 2004)
"We report two cases of refractory chronic graft-versus-host disease after donor lymphocyte infusions in which the skin lesions improved dramatically with the use of intravenous pulses of lidocaine."7.71Beneficial effect of intravenous lidocaine in cutaneous chronic graft-versus-host disease secondary to donor lymphocyte infusion. ( Ahmed, H; Ball, ED; Bashey, A; Carrier, E; Coutinho, M; Holman, P; Paton, EJ; Simoes, BP; Stracieri, AB; Voltarelli, JC, 2001)
"Intravenous administration of high doses of lidocaine has been used as a treatment modality for tinnitus."7.69[The lidocaine test in tinnitus. Determination of its current status]. ( Davis, A; Hörmann, K; Schmidt, H; Stasche, N, 1994)
"Despite continuing controversies regarding its antiarrhythmic and antifibrillatory efficacy lidocaine is frequently used for the treatment of ventricular arrhythmias occurring in the early phase of acute myocardial infarction (MI)."7.69Facilitation of reentry by lidocaine in canine myocardial infarction. ( Fazekas, T; Lazzara, R; Mabo, P; Patterson, E; Scherlag, BJ, 1994)
"A 52-year-old man with intractable cough refractory to standard therapy was treated successfully with chronic nebulized lidocaine."7.69Nebulized lidocaine in the treatment of refractory cough. ( Trochtenberg, S, 1994)
"To evaluate the pharmacodynamics of intravenous lidocaine in patients with acute-onset and chronic ventricular arrhythmias."7.68Comparative pharmacodynamics of intravenous lidocaine in patients with acute and chronic ventricular arrhythmias. ( Destache, CJ; Hilleman, DE; Hunter, CB; Mohiuddin, SM; Mooss, AN; Sketch, MH, 1992)
"Twenty-eight anesthetized mongrel dogs were studied 2 to 74 months after experimental myocardial infarction in order to examine the effects of procainamide, lidocaine and acetylstrophanthidin on conduction within the infarcted region and the way such effects relate to changes in body surface potentials and antiarrhythmic efficacy."7.67Differential effects of procainamide, lidocaine and acetylstrophanthidin on body surface potentials and epicardial conduction in dogs with chronic myocardial infarction. ( Balke, CW; de Langen, CD; Hanich, RF; Kadish, AH; Levine, JH; Michelson, EL; Moore, EN; Spear, JF, 1988)
"Pilsicainide is a newly synthesized antiarrhythmic agent with class Ic properties."6.69Pilsicainide for conversion and maintenance of sinus rhythm in chronic atrial fibrillation: a placebo-controlled, multicenter study. ( Aonuma, K; Azegami, K; Igawa, M; Nishizaki, M; Okishige, K; Yamawaki, N, 2000)
"Chronic neurogenic facial pain is commonly resistant to treatment and is often the source of significant patient morbidity."6.69Chronic neurogenic facial pain: lack of response to intravenous phentolamine. ( Chaudry, A; Keith, DA; Maciewicz, RJ; Scrivani, SJ, 1999)
"Lidocaine infusion reduced mechano-hyperalgesia but had no effect on mechano-allodynia or heat-hyperalgesia."5.35C-fiber spontaneous discharge evoked by chronic inflammation is suppressed by a long-term infusion of lidocaine yielding nanogram per milliliter plasma levels. ( Bennett, GJ; Xiao, WH, 2008)
"Polidocanol injections have been used to treat chronic Achilles tendinopathy in clinical settings, but the few studies published show inconsistent results."5.27No beneficial effect of Polidocanol treatment in Achilles tendinopathy: a randomised controlled trial. ( Ebbesen, BH; Gregersen, HE; Mølgaard, CM; Olesen, JL; Simonsen, O, 2018)
" In smokers, L systemic bioavailability was decreased secondary to a marked increase in oral clearance, reflecting induction of drug-metabolizing activity."5.26Effects of smoking and chronic hepatitis B on lidocaine and indocyanine green kinetics. ( Huet, PM; Lelorier, J, 1980)
"To determine the effectiveness of aerosolised carcainium chloride (VRP700) in controlling cough in patients with IIP."5.22Antitussive effect of carcainium chloride in patients with chronic cough and idiopathic interstitial pneumonias: A pilot study. ( Fontana, GA; Franciosi, L; Lavorini, F; Page, CP; Spina, D; Walker, MJ, 2016)
"Intravenous perioperative lidocaine decreases the incidence and severity of PPSP after breast cancer surgery."5.16Perioperative intravenous lidocaine decreases the incidence of persistent pain after breast surgery. ( Grigoras, A; Lee, P; Sattar, F; Shorten, G, 2012)
" In this study, we evaluated the AMPA/GluR5 receptor antagonist NS1209 for efficacy, safety, and tolerability in comparison with placebo and lidocaine for the treatment of chronic neuropathic pain and allodynia in patients with peripheral nerve injury."5.14The efficacy of the AMPA receptor antagonist NS1209 and lidocaine in nerve injury pain: a randomized, double-blind, placebo-controlled, three-way crossover study. ( Almqvist, PM; Finnerup, NB; Gormsen, L; Jensen, TS, 2009)
"To determine the impact of the lidocaine patch 5% on pain qualities associated with chronic pain from postherpetic neuralgia (PHN), painful diabetic neuropathy (DN), and low-back pain (LBP), using the Neuropathic Pain Scale (NPS)."5.11Effectiveness of the lidocaine patch 5% on pain qualities in three chronic pain states: assessment with the Neuropathic Pain Scale. ( Argoff, CE; Galer, BS; Gammaitoni, AR; Jensen, MP; Oleka, N, 2004)
"The values for tinnitus loudness, level of irritation caused by the tinnitus and subjective effectiveness of the therapy - measured by means of the visual analog scale (VAS) - showed no significant change, although the most marked improvement was indicated for caroverine."5.11[Use of the round window micro cath for inner ear therapy - results of a placebo-controlled, prospective study on chronic tinnitus]. ( Heermann, R; Lenarz, T; Schwab, B, 2004)
"To assess the effectiveness and safety of the lidocaine patch 5%, a targeted peripheral analgesic, in the treatment of postherpetic neuralgia, painful diabetic neuropathy, and low back pain patients with incomplete responses to their current analgesic treatment regimen containing gabapentin."5.10Lidocaine patch 5% with systemic analgesics such as gabapentin: a rational polypharmacy approach for the treatment of chronic pain. ( Drass, M; Nalamachu, S; Patel, N; White, WT, 2003)
"Our study clearly demonstrates that the therapeutic use of topical nifedipine and lidocaine ointment should be extended to the conservative treatment of chronic anal fissure."5.10Topical nifedipine with lidocaine ointment vs. active control for treatment of chronic anal fissure: results of a prospective, randomized, double-blind study. ( Antropoli, C; Antropoli, M; Attena, F; Balzano, A; Bove, A; De Stefano, G; Molino, D; Perrotti, P, 2002)
"This multicentre, double-blind, placebo-controlled, parallel-group study assessed the efficacy and safety of using Emla (lignocaine/prilocaine) anaesthetic cream to achieve pain control during sharp debridement of chronic leg ulcers of arterial, venous or arteriovenous aetiology."5.09Using a topical anaesthetic cream to reduce pain during sharp debridement of chronic leg ulcers. ( Baxter, M; Gottschalk, R; Lycka, B; Murphy, F; Nevin, K; Rosenthal, D, 2001)
"Although the lignocaine (lidocaine)-prilocaine cream EMLA has been extensively studied for the relief of acute treatment-related pain from sharp leg ulcer debridement, no data exist on systemic absorption from prolonged application in patients with chronically painful ulcers."5.09Plasma concentrations of lignocaine and prilocaine after a 24-h application of analgesic cream (EMLA) to leg ulcers. ( Lillieborg, S; Stymne, B, 2001)
"Topical application of nitroglycerine represents a new, easily handled, and effective alternative in the treatment of anal fissures."5.08Local nitroglycerin for treatment of anal fissures: an alternative to lateral sphincterotomy? ( Bacher, H; Cerwenka, H; El-Shabrawi, A; Mischinger, HJ; Pfeifer, J; Schweiger, W; Werkgartner, G, 1997)
"Twenty patients with chronic pain who previously had obtained analgesia from epidural clonidine and lignocaine agreed to participate in a double-blind crossover study of lumbar epidural clonidine (150 micrograms), lignocaine (40 mg) and the combination of clonidine (150 microgram) and lignocaine (40 mg), all drugs were given in a volume of 3 ml."5.08A double-blind randomised comparison of the effects of epidural clonidine, lignocaine and the combination of clonidine and lignocaine in patients with chronic pain. ( Glynn, C; O'Sullivan, K, 1996)
"To evaluate the efficacy of continuous administration of 50% nitrous oxide in oxygen for reducing pain during flexible fiberoptic bronchoscopy 32 children aged 3-60 months were randomly assigned to an experimental or a control group."5.08[Bronchial endoscopy under local anesthesia and pain in children. The value of a nitrous oxide-oxygen combination]. ( Dupont, D; Garcia, J; Hayem, C; Roure, P, 1998)
"To assess the efficacy of 4% topical lidocaine in spheno-palatine blocks, a randomized controlled trial was carried out on patients with chronic muscle pain syndromes."5.08The use of topical 4% lidocaine in spheno-palatine ganglion blocks for the treatment of chronic muscle pain syndromes: a randomized, controlled trial. ( Delaney, G; Heck, C; Janzen, V; McCain, GA; Russell, AL; Scudds, RA; Teasell, RW; Varkey, G; Woodbury, GM, 1995)
"Sixteen men and 25 women with pain in one or more cervical zygapophyseal joints after automobile accidents (mean age, 43 years; median duration of pain, 39 months) were randomly assigned to receive an intraarticular injection of either bupivacaine (0."5.07Lack of effect of intraarticular corticosteroids for chronic pain in the cervical zygapophyseal joints. ( Barnsley, L; Bogduk, N; Lord, SM; Wallis, BJ, 1994)
"In a double blind study, 21 patients with chronic spinal cord injury (SCI) pain underwent placement of a lumbar subarachnoid catheter and injection of placebo and lidocaine."5.07Diagnostic spinal anaesthesia in chronic spinal cord injury pain. ( Donovan, WH; Loubser, PG, 1991)
"In a randomized double-blind, cross-over study the effect of intravenous lidocaine (5 mg/kg body weight) on the symptoms and signs of painful diabetic neuropathy of more than 6 months duration has been evaluated."5.06Intravenous lidocaine infusion--a new treatment of chronic painful diabetic neuropathy? ( Angelo, HR; Dejgård, A; Hilsted, J; Kastrup, J; Petersen, P, 1987)
"The efficacy and safety of intravenous tocainide were compared with intravenous lidocaine in patients with chronic ventricular arrhythmias in a double-blind, parallel study."5.06Double-blind randomized comparison of intravenous tocainide versus lidocaine in the treatment of chronic ventricular arrhythmias. ( Butler, ML; Esterbrooks, D; Hilleman, DE; Mohiuddin, SM; Mooss, AN; Sketch, MH; Stengel, LA, 1987)
"The long-term safety of patient-administered nebulized lidocaine for control of chronic cough has not been established."3.79Long-term safety of nebulized lidocaine for adults with difficult-to-control chronic cough: a case series. ( Hahn, PY; Keogh, KA; Lim, KG; Morgenthaler, TI; Olson, EJ; Rank, MA, 2013)
" We analyzed data from 5 open-label clinical trials of lidocaine patch 5% in osteoarthritis knee pain and chronic low back pain that were 2 to 12 weeks in duration."3.77Treatment satisfaction in osteoarthritis and chronic low back pain: the role of pain, physical and emotional functioning, sleep, and adverse events. ( Dworkin, RH; Galer, BS; Gammaitoni, AR; Gould, E; Jensen, MP; Jones, BA; Xiang, Q, 2011)
"The clinical and therapeutical data of a 2 years follow up show that in these 7 cases of chronic benign pain, treated by injecting local anaesthetic (lidocaine 0."3.75[Our experiences in chronic benign pain by injecting local anaesthetic into scars]. ( Barbagli, P; Bollettin, R, 2009)
"The present study investigated the effects of different doses of intrathecal lidocaine on established thermal hyperalgesia and tactile allodynia in the chronic constriction injury model of neuropathic pain, defined the effective drug dose range, the duration of pain-relief effects, and the influence of this treatment on the body and tissues."3.75Effects of intrathecal lidocaine on hyperalgesia and allodynia following chronic constriction injury in rats. ( Gu, Y; Su, D; Tian, J; Wang, X; Wu, Y, 2009)
"The proportion of chronic pain patients with suspected neuropathic pain who will have clinically meaningful pain relief with intravenous (IV) lidocaine and the clinical characteristics that identify these patients have not been described previously."3.74Multivariate analysis of chronic pain patients undergoing lidocaine infusions: increasing pain severity and advancing age predict likelihood of clinically meaningful analgesia. ( Carroll, I; Gaeta, R; Mackey, S, 2007)
"The effects of an analgesic treatment (lidocaine patches) on brain activity in chronic low back pain (CBP) and in knee osteoarthritis (OA) were investigated using serial fMRI (contrasting fMRI between before and after two weeks of treatment)."3.74A preliminary fMRI study of analgesic treatment in chronic back pain and knee osteoarthritis. ( Apkarian, AV; Baliki, MN; Geha, PY; Harden, N; Jabakhanji, R; Schnitzer, TJ, 2008)
"From 2001 to 2006, we performed a retrospective study of patients suffering from chronic unilateral or bilateral tinnitus that was previously ineffectively treated by oral drugs [betahistine (Betaserc), extract of Ginkgo biloba (EGb 761), tanakan (Tebokan), and cinnarizine-dimenhydrinate (Arlevert), singly or in combination]."3.74Multimodal therapy for chronic tinnitus. ( Achiemere, G; Alpini, D; Hahn, A; Klement, V; Radkova, L; Strouhal, J, 2008)
" Three studies are presented that provide preliminary evidence for the utility of the NPS for characterizing distinct pain qualities and changes in pain qualities in patients treated with the lidocaine patch 5% for a variety of neuropathic and non-neuropathic chronic pain conditions, including low-back pain, osteoarthritis, post-herpetic neuralgia, and painful diabetic neuropathy."3.72Introduction: chronic pain studies of the lidocaine patch 5% using the Neuropathic Pain Scale. ( Jensen, MP, 2004)
"We conducted a retrospective review of the charts of thirty-four patients with neck pain who met three criteria for the diagnosis of shoulder impingement syndrome: (1) a positive impingement sign with pain referred to the neck, (2) radiographic abnormalities, and (3) relief of neck pain after injection of lidocaine and cortisone into the subacromial space."3.72Shoulder impingement presenting as neck pain. ( Gorski, JM; Schwartz, LH, 2003)
"We report two cases of refractory chronic graft-versus-host disease after donor lymphocyte infusions in which the skin lesions improved dramatically with the use of intravenous pulses of lidocaine."3.71Beneficial effect of intravenous lidocaine in cutaneous chronic graft-versus-host disease secondary to donor lymphocyte infusion. ( Ahmed, H; Ball, ED; Bashey, A; Carrier, E; Coutinho, M; Holman, P; Paton, EJ; Simoes, BP; Stracieri, AB; Voltarelli, JC, 2001)
"Despite continuing controversies regarding its antiarrhythmic and antifibrillatory efficacy lidocaine is frequently used for the treatment of ventricular arrhythmias occurring in the early phase of acute myocardial infarction (MI)."3.69Facilitation of reentry by lidocaine in canine myocardial infarction. ( Fazekas, T; Lazzara, R; Mabo, P; Patterson, E; Scherlag, BJ, 1994)
"Seventeen patients with non-infectious chronic cystitis (NICC) (9 with interstitial cystitis, 6 patients with radiation cystitis, 1 with chemocystitis and 1 with lupoid cystitis) were treated with electromotive administration of intravesical lidocaine and dexamethasone followed by hydrodistension of the bladder."3.69Intravesical electromotive drug administration for the treatment of non-infectious chronic cystitis. ( Knoll, M; Pflüger, H; Plas, E; Riedl, CR; Stephen, RL, 1997)
"A 52-year-old man with intractable cough refractory to standard therapy was treated successfully with chronic nebulized lidocaine."3.69Nebulized lidocaine in the treatment of refractory cough. ( Trochtenberg, S, 1994)
"Intravenous administration of high doses of lidocaine has been used as a treatment modality for tinnitus."3.69[The lidocaine test in tinnitus. Determination of its current status]. ( Davis, A; Hörmann, K; Schmidt, H; Stasche, N, 1994)
"A case of interstitial cystitis in a patient with a 5-year history treated by intravesical instillations of Lidocaine is reported."3.68Chronic interstitial cystitis. Successful treatment with intravesical idocaine. ( Champilomatos, P; Giannakopoulos, X, 1992)
"To evaluate the pharmacodynamics of intravenous lidocaine in patients with acute-onset and chronic ventricular arrhythmias."3.68Comparative pharmacodynamics of intravenous lidocaine in patients with acute and chronic ventricular arrhythmias. ( Destache, CJ; Hilleman, DE; Hunter, CB; Mohiuddin, SM; Mooss, AN; Sketch, MH, 1992)
"Diagnostic epidural blocks were performed on 27 chronic pain patients sequentially using saline, fentanyl, and lidocaine solution."3.67Diagnostic epidural opioid technique. ( Ellis, JS; Hoffman, J; Ramamurthy, S; Schoenfeld, LS; Walsh, NE, 1989)
"Twenty-eight anesthetized mongrel dogs were studied 2 to 74 months after experimental myocardial infarction in order to examine the effects of procainamide, lidocaine and acetylstrophanthidin on conduction within the infarcted region and the way such effects relate to changes in body surface potentials and antiarrhythmic efficacy."3.67Differential effects of procainamide, lidocaine and acetylstrophanthidin on body surface potentials and epicardial conduction in dogs with chronic myocardial infarction. ( Balke, CW; de Langen, CD; Hanich, RF; Kadish, AH; Levine, JH; Michelson, EL; Moore, EN; Spear, JF, 1988)
"A 38-year-old white woman developed left medical rectus myositis possibly due to an immune response to mepivacaine (Carbocaine) injected around her upper left first molar."3.66Vertical pendular nystagmus in chronic myositis of medial and lateral rectus. ( Goldberg, RT, 1978)
"The plasma half lives of antipyrine, paracetamol, and lignocaine given by mouth were measured in 23 patients with stable chronic liver diseases of varying severity."3.65Antipyrine, paracetamol, and lignocaine elimination in chronic liver disease. ( Adjepon-Yamoah, KK; Finlayson, ND; Forrest, JA; Prescott, LF, 1977)
"Background Postoperative nausea and vomiting (PONV) are among the most common unpleasant and distressing adverse events following surgery under general anesthesia."2.87The Role of Endoscopic Sphenopalatine Ganglion Block on Nausea and Vomiting After Sinus Surgery. ( Abubaker, AK; Al-Qudah, MA, 2018)
"Migraine affects more than 35 million people in the United States of America, and 10% of the population in the world."2.87Effectiveness of surgical treatment in chronic migraine. ( Amaya-Blas, FJ; Castro-Góvea, Y; Chacón-Moreno, H; Coutiño, R; García-Pérez, MM; Marfil-Rivera, A; Mecott, GA; Pérez-Porras, S; Tamayo-Esquivel, ML, 2018)
"Bupivacaine help the lower pain values and less additional painkiller need after FESS."2.82Different anesthetic agents-soaked sinus packings on pain management after functional endoscopic sinus surgery: which is the most effective? ( Arıkan, OK; Haytoğlu, S; Kuran, G; Muluk, NB, 2016)
"The operation time, postoperative pain, amount of intraoperative blood loss, postoperative hemorrhage and complications were assessed."2.77Comparison of ropivacaine, bupivacaine and lidocaine in the management of post-tonsillectomy pain. ( Kapusuz, Z; Ozkiriş, M; Saydam, L, 2012)
"Rotator cuff tendinosis is a common problem with significant health and economic effects."2.71A prospective, double-blind, randomized clinical trial comparing subacromial injection of betamethasone and xylocaine to xylocaine alone in chronic rotator cuff tendinosis. ( Alvarez, CM; Griffin, S; Jackowski, D; Kirkley, A; Litchfield, R, 2005)
"The magnesium-lignocaine treatment was painful in 52% of patients compared with 8% with lignocaine alone (number-needed-to-harm 2."2.70Magnesium Bier's block for treatment of chronic limb pain: a randomised, double-blind, cross-over study. ( Glynn, CJ; Tramèr, MR, 2002)
"Atypical odontalgia is a distressing and unusual chronic orofacial pain condition."2.69Analysis of 50 patients with atypical odontalgia. A preliminary report on pharmacological procedures for diagnosis and treatment. ( Chisholm, K; Cousins, MJ; Vickers, ER; Walker, S, 1998)
"Pilsicainide is a newly synthesized antiarrhythmic agent with class Ic properties."2.69Pilsicainide for conversion and maintenance of sinus rhythm in chronic atrial fibrillation: a placebo-controlled, multicenter study. ( Aonuma, K; Azegami, K; Igawa, M; Nishizaki, M; Okishige, K; Yamawaki, N, 2000)
"Chronic neurogenic facial pain is commonly resistant to treatment and is often the source of significant patient morbidity."2.69Chronic neurogenic facial pain: lack of response to intravenous phentolamine. ( Chaudry, A; Keith, DA; Maciewicz, RJ; Scrivani, SJ, 1999)
"Lidocaine caused an increase in all CPTs at the umbilicus and the knee reaching a statistical significance at 5 Hz for the umbilicus only."2.68Quantitative assessment of differential sensory blockade after lumbar epidural lidocaine. ( Irving, G; Tay, B; Wallace, MS, 1997)
"Pain was scored on a visual analogue scale (0 to 100)."2.68Isometric abduction muscle activation in patients with rotator tendinosis of the shoulder. ( Brox, JI; Røe, C; Saugen, E; Vøllestad, NK, 1997)
"Cough was recorded with a microphone and then computer analyzed."2.67Pathogenesis of chronic persistent cough associated with gastroesophageal reflux. ( Breslin, AB; Ing, AJ; Ngu, MC, 1994)
"Whereas suppression of extrasystole was most marked after ajmalin, propafenon showed the longest period of activity."2.65[Antiarrhythmic drugs in chronic ventricular extrasystole (author's transl)]. ( Himmler, C; Klein, G; Neiss, A; Schlegel, J; Wirtzfeld, A, 1980)
"Some mechanisms of the development of neuropathic pain have been proposed; 1) sprouting of A beta fibers to the superficial layer of the dorsal horn, 2) ectopic discharge in the dorsal root ganglion and/or in neuroma at the nerve stump, 3) spinal sensitization."2.44[Mechanisms of the development of neuropathic pain and its treatment]. ( Yamamoto, T, 2008)
"Chronic pain is now viewed as a biopsychosocial phenomenon, in which biological, psychological, and social factors are at work."2.44Practical management strategies for the chronic pain patient. ( Forde, G; Stanos, S, 2007)
"Managing patients with chronic neuropathic pain is a common clinical challenge due to variability in individual symptoms, mechanisms, and treatment responses."2.42Diagnosis and management of neuropathic pain: a balanced approach to treatment. ( Nicholson, BD, 2003)
"Patients with refractory chronic migraine have substantial disability and have failed many acute and preventive medications."1.62Ketamine for Refractory Chronic Migraine: An Observational Pilot Study and Metabolite Analysis. ( Denk, W; Katz, D; Lauritsen, C; Lovett, J; Moaddel, R; Schwenk, ES; Silberstein, SD; Torjman, MC; Wainer, IW, 2021)
"Even though chronic abdominal pain is 1 of the most common reasons for hospital visits, diagnostic testing is often time-consuming and treatment is inadequate."1.56Sonography-guided trigger point injections in abdominal myofascial pain syndrome. ( Cha, J; Cha, JH; Kim, DH; Rhim, HC, 2020)
"Therapeutic management of Chronic Migraine (CM), often associated with Medication Overuse Headache (MOH), is chiefly empirical, as no biomarker predicting or correlating with clinical efficacy is available to address therapeutic choices."1.48Neurophysiological correlates of clinical improvement after greater occipital nerve (GON) block in chronic migraine: relevance for chronic migraine pathophysiology. ( Altieri, M; Di Piero, V; Petolicchio, B; Puledda, F; Ruggiero, S; Sasso D'Elia, T; Schoenen, J; Torrieri, MC; Toscano, M; Verzina, A; Vicenzini, E; Viganò, A, 2018)
"Deep mechanical hyperalgesia observed after RCS at -3 degrees C lasted longer ( approximately 6 weeks) and was severer than RCS at 4 degrees C."1.36Persistent deep mechanical hyperalgesia induced by repeated cold stress in rats. ( Mizumura, K; Nasu, T; Taguchi, T, 2010)
"Lidocaine infusion reduced mechano-hyperalgesia but had no effect on mechano-allodynia or heat-hyperalgesia."1.35C-fiber spontaneous discharge evoked by chronic inflammation is suppressed by a long-term infusion of lidocaine yielding nanogram per milliliter plasma levels. ( Bennett, GJ; Xiao, WH, 2008)
"5% Lidocaine patches have been used for treatment of chronic neuropathic pain in adults and we have found this to be effective in management of localized neuropathic pain in children and adolescents."1.35Lidocaine 5% patch for localized chronic neuropathic pain in adolescents: report of five cases. ( Cunliffe, M; Nayak, S, 2008)
"Pelvic pain was detected 5 days after antigen instillation and was sustained beyond 30 days, indicating the development of chronic pain."1.35Experimental autoimmune prostatitis induces chronic pelvic pain. ( Rudick, CN; Schaeffer, AJ; Thumbikat, P, 2008)
"To analyze the effect of lidocaine on postoperative pain relief, we performed compression of the right sciatic nerve in Wistar rats and observed the differences on behavior between the group that received lidocaine and the group that was not treated with the local anesthetics pre-operatively."1.35Preemptive analgesic effect of lidocaine in a chronic neuropathic pain model. ( Almeida, JP; Batista, IM; Batista, LM; Carvalho, CH; Castro-Costa, CM; Castro-Costa, SB, 2009)
"Transient abducens nerve palsy rarely occurs after an intranasal sphenopalatine nerve block."1.34Transient abducens nerve palsy during endoscopic sinus surgery: report of three cases. ( Kim, HD; Lim, SC, 2007)
"Chronic pain is common in patients with spinal cord injury (SCI)."1.33Pain management with interventional spine therapy in patients with spinal cord injury: a case series. ( Chiodo, A, 2005)
"The pathophysiology of many types of chronic headaches is not well understood."1.33Cervicogenic headache in patients with presumed migraine: missed diagnosis or misdiagnosis? ( Cook, AJ; Hamill-Ruth, RJ; Rowlingson, JC; Yi, X, 2005)
"It is debated as to whether Achilles tendonitis (AT) has an inflammatory component."1.32Preliminary results of colour Doppler-guided intratendinous glucocorticoid injection for Achilles tendonitis in five patients. ( Bliddal, H; Koenig, MJ; Qvistgaard, E; Terslev, L; Torp-Pedersen, S, 2004)
"Five infusions were given for status migrainosus in three patients, with four of these infusions successfully relieving the headache."1.31Intravenous lignocaine infusions for severe chronic daily headache. ( Hand, PJ; Stark, RJ, 2000)
"Chronic anal fissure is the main cause of anal pain and is very common."1.31Open lateral sphincterotomy is still the best treatment for chronic anal fissure. ( Argov, S; Levandovsky, O, 2000)
"Clonidine was more potent in CCI then in CFA rats in reducing the response to cold."1.30The cold plate as a test of nociceptive behaviors: description and application to the study of chronic neuropathic and inflammatory pain models. ( Franssen, M; Goff, JR; Janni, G; Jasmin, L; Kohan, L, 1998)
"Lidocaine was given as a 1."1.28Predictive performance of Bayesian and nonlinear least-squares regression programs for lidocaine. ( Destache, CJ; Hilleman, DE; Lang, PT; Mohiuddin, SJ, 1992)
"Furthermore, autonomic hyperreflexia is completely established within 24 h after CST in the rat."1.28Chronic cervical spinal cord injury and autonomic hyperreflexia in rats. ( Osborn, JW; Schramm, LP; Taylor, RF, 1990)
"Although seldom recognized, sprains of the carpometacarpal joints as part of a range of injury which includes subluxations, dislocations, and fractures are apparently common."1.26Chronic sprains of the carpometacarpal joints. ( Bryan, RS; Dobyns, JH; Joseph, RB; Linscheid, RL, 1981)
" In smokers, L systemic bioavailability was decreased secondary to a marked increase in oral clearance, reflecting induction of drug-metabolizing activity."1.26Effects of smoking and chronic hepatitis B on lidocaine and indocyanine green kinetics. ( Huet, PM; Lelorier, J, 1980)

Research

Studies (216)

TimeframeStudies, this research(%)All Research%
pre-199042 (19.44)18.7374
1990's54 (25.00)18.2507
2000's82 (37.96)29.6817
2010's33 (15.28)24.3611
2020's5 (2.31)2.80

Authors

AuthorsStudies
Brillantino, A1
Renzi, A1
Talento, P1
Iacobellis, F1
Brusciano, L1
Monaco, L1
Izzo, D1
Giordano, A1
Pinto, M1
Fantini, C1
Gasparrini, M1
Schiano Di Visconte, M1
Milazzo, F1
Ferreri, G1
Braini, A1
Cocozza, U1
Pezzatini, M1
Gianfreda, V1
Di Leo, A1
Landolfi, V1
Favetta, U1
Agradi, S1
Marino, G1
Varriale, M1
Mongardini, M1
Pagano, CEFA1
Contul, RB1
Gallese, N1
Ucchino, G1
D'Ambra, M1
Rizzato, R1
Sarzo, G1
Masci, B1
Da Pozzo, F1
Ascanelli, S1
Foroni, F1
Palumbo, A1
Liguori, P1
Pezzolla, A1
Marano, L1
Capomagi, A1
Cudazzo, E1
Babic, F1
Geremia, C1
Bussotti, A1
Cicconi, M1
Di Sarno, A1
Mongardini, FM1
Brescia, A1
Lenisa, L1
Mistrangelo, M1
Sotelo, MLS1
Vicenzo, L1
Longo, A1
Docimo, L1
Tangbumrungtham, N1
Hwang, PH1
Maul, X1
Borchard, NA1
Dholakia, SS1
Patel, ZM1
Nayak, JV1
Choby, G1
Mansiz-Kaplan, B1
Nacir, B1
Pervane-Vural, S1
Duyur-Cakit, B1
Genc, H1
Hammodi, A1
Rhim, HC1
Cha, JH1
Cha, J1
Kim, DH1
Schwenk, ES1
Torjman, MC1
Moaddel, R1
Lovett, J1
Katz, D1
Denk, W1
Lauritsen, C1
Silberstein, SD1
Wainer, IW1
Lee, HG1
Grossman, SK1
Valdes-Rodriguez, R1
Berenato, F1
Korbutov, J1
Chan, YH1
Lavery, MJ1
Yosipovitch, G1
Purcell, A1
Buckley, T1
Fethney, J1
King, J1
Moyle, W1
Marshall, AP1
Ebbesen, BH1
Mølgaard, CM1
Olesen, JL1
Gregersen, HE1
Simonsen, O1
Amaya-Blas, FJ1
Mecott, GA1
Marfil-Rivera, A1
Tamayo-Esquivel, ML1
García-Pérez, MM1
Chacón-Moreno, H1
Pérez-Porras, S1
Coutiño, R1
Castro-Góvea, Y1
Abubaker, AK1
Al-Qudah, MA1
Tripathi, SJ1
Chakraborty, S1
Srikumar, BN1
Raju, TR1
Shankaranarayana Rao, BS1
Viganò, A1
Torrieri, MC1
Toscano, M1
Puledda, F1
Petolicchio, B1
Sasso D'Elia, T1
Verzina, A1
Ruggiero, S1
Altieri, M1
Vicenzini, E1
Schoenen, J1
Di Piero, V1
Farmer, RL1
Garg, RK1
Afifi, AM1
Zheng, Y1
Hou, X1
Yang, S1
Hsieh, LF1
Hsu, WC1
Lin, YJ1
Wu, SH1
Chang, KC1
Chang, HL1
Kim, E1
Lee, JH1
Phipps, C1
Lupo-Stanghellini, MT1
Flowers, ME1
Rocha, ID1
Cristante, AF1
Marcon, RM1
Oliveira, RP1
Letaif, OB1
Barros Filho, TE1
Valdes, CJ1
Al Badaai, Y1
Bogado, M1
Samaha, M1
Altenburg, A1
El-Haj, N1
Micheli, C1
Puttkammer, M1
Abdel-Naser, MB1
Zouboulis, CC1
Peloso, PM1
Gross, A3
Haines, T3
Trinh, K3
Goldsmith, CH3
Burnie, SJ1
Haytoğlu, S1
Kuran, G1
Muluk, NB1
Arıkan, OK1
Mishra, AK1
Sinha, VR1
Nilakantan, A1
Singh, DK1
Lavorini, F1
Spina, D1
Walker, MJ1
Franciosi, L1
Page, CP1
Fontana, GA1
Schechtman, SA1
Wertz, AP1
Shanks, A1
Thompson, A1
Tremper, K1
Pynnonen, MA1
Healy, DW1
Hanaoka, K1
Arita, H1
Nagase, M1
Ide, Y1
Tagami, M1
Hayashida, M1
Hahn, A1
Radkova, L1
Achiemere, G1
Klement, V1
Alpini, D1
Strouhal, J1
Medhi, B1
Rao, RS1
Prakash, A1
Prakash, O1
Kaman, L1
Pandhi, P1
Forde, G2
Stanos, S1
Yamamoto, T1
Baliki, MN1
Geha, PY1
Jabakhanji, R1
Harden, N1
Schnitzer, TJ1
Apkarian, AV1
Gormsen, L1
Finnerup, NB1
Almqvist, PM1
Jensen, TS1
Nasu, T1
Taguchi, T1
Mizumura, K1
Cohen, SP1
Kapoor, SG1
Rathmell, JP1
Batista, LM1
Batista, IM1
Almeida, JP1
Carvalho, CH1
Castro-Costa, SB1
Castro-Costa, CM1
Barbagli, P1
Bollettin, R1
Dworkin, RH1
Jensen, MP3
Gould, E1
Jones, BA1
Xiang, Q1
Galer, BS2
Gammaitoni, AR2
Konstantinidis, I1
Chatziavramidis, A1
Tsakiropoulou, E1
Malliari, H1
Constantinidis, J1
Rose, K1
Ooi, L1
Dalle, C1
Robertson, B1
Wood, IC1
Gamper, N1
Barkin, RL1
Barkin, SJ1
Irving, GA1
Gordon, A1
Watanabe, I1
Okumura, Y1
Ohkubo, K1
Nagashima, K1
Sonoda, K1
Mano, H1
Kofune, M1
Hirayama, A1
Grigoras, A1
Lee, P1
Sattar, F1
Shorten, G1
Neuhaus, T1
Ko, YD1
Stier, S1
Ozkiriş, M1
Kapusuz, Z1
Saydam, L1
Koo Ng, NK1
Young, D1
McGarry, GW1
Lim, KG1
Rank, MA1
Hahn, PY1
Keogh, KA1
Morgenthaler, TI1
Olson, EJ1
Kim, DS1
Jeong, TY1
Kim, YK1
Chang, WH1
Yoon, JG1
Lee, SC1
Argoff, CE4
Muellbacher, W1
Richards, C1
Ziemann, U1
Wittenberg, G1
Weltz, D1
Boroojerdi, B1
Cohen, L1
Hallett, M1
Tramèr, MR1
Glynn, CJ2
Perrotti, P1
Bove, A1
Antropoli, C1
Molino, D1
Antropoli, M1
Balzano, A1
De Stefano, G1
Attena, F1
Merenstein, D1
Rosenbaum, D1
Landis, BN1
Beghetti, M1
Morel, DR1
Giger, R1
Rimensberger, PC1
Lacroix, JS1
Gorski, JM1
Schwartz, LH1
Rosenthal, D1
Murphy, F1
Gottschalk, R1
Baxter, M1
Lycka, B1
Nevin, K1
Gordon, DB1
Davis, MD1
Fowler, E2
White, WT1
Patel, N1
Drass, M1
Nalamachu, S1
Hinkel, A1
Pannek, J1
Schwab, B1
Lenarz, T1
Heermann, R1
Koenig, MJ1
Torp-Pedersen, S1
Qvistgaard, E1
Terslev, L1
Bliddal, H1
Nicholson, BD1
Haanpää, M1
Yelland, MJ2
Mar, C1
Pirozzo, S1
Schoene, ML2
Vercoe, P1
Manchikanti, L1
Boswell, MV1
Singh, V1
Pampati, V1
Damron, KS1
Beyer, CD1
Takada, Y1
Isobe, S1
Okada, M1
Ando, A1
Nonokawa, M1
Inden, Y1
Tomita, Y1
Suzuki, A1
Hirai, M1
Murohara, T1
Oleka, N1
Dashfield, AK1
Taylor, MB1
Cleaver, JS1
Farrow, D1
Alvarez, CM1
Litchfield, R1
Jackowski, D1
Griffin, S1
Kirkley, A1
Shih, C1
Lin, GY1
Yueh, KC1
Lin, JJ1
Peloso, P2
Aker, P1
Heckmann, JG1
Maihöfner, C1
Lanz, S1
Rauch, C1
Neundörfer, B1
Rabago, D1
Best, TM1
Beamsley, M1
Patterson, J1
Villamil, AG1
Bandi, JC1
Galdame, OA1
Gerona, S1
Gadano, AC1
Yi, X1
Cook, AJ1
Hamill-Ruth, RJ1
Rowlingson, JC1
Wolff, AP1
Groen, GJ1
Wilder-Smith, OH1
Richardson, J1
van Egmond, J1
Crul, BJ1
Chiodo, A1
Burgess, C1
Ravenscroft, AJ1
Amir, R1
Bennett, GJ2
Cummins, TR1
Durieux, ME1
Gerner, P1
Gold, MS1
Porreca, F1
Strichartz, GR1
Kumar, CM1
Dowd, TC1
Hawthorne, M1
Sotgiu, ML2
Valente, M1
Caramenti, GC1
Biella, GE1
Sabatino, MD1
Borrelli, M1
Cautiero, P1
Romano, M1
Parmeggiani, P1
Marte, A1
Mayer, EA1
Kim, HD1
Lim, SC1
Langford, CF1
Udvari Nagy, S1
Ghoniem, GM1
Hu, XY1
Wang, DX1
Hooper, RA1
Frizzell, JB1
Faris, P1
Dagenais, S1
Del Mar, C1
Burnie, S1
Vosoughian, M1
Dabbagh, A1
Rajaei, S1
Maftuh, H1
Zeng, Y1
Wu, XM1
Li, YF1
Yu, SZ1
Carroll, I1
Gaeta, R1
Mackey, S1
Carroll, IR1
Kaplan, KM1
Mackey, SC1
Fullerton, BD1
Rudick, CN1
Schaeffer, AJ1
Thumbikat, P1
Nayak, S1
Cunliffe, M1
Xiao, WH1
Tian, J1
Gu, Y1
Su, D1
Wu, Y1
Wang, X1
Gottehrer, NR1
Atkinson, RL1
Klein, G1
Wirtzfeld, A1
Schlegel, J1
Himmler, C1
Neiss, A1
Maxwell, RE1
Warfield, CA1
Stein, JM1
Parer, C1
Rodier, M1
Batier, C1
Marchal, J1
Mirouze, J1
Duthie, AM1
Ingham, V1
Joseph, RB1
Linscheid, RL1
Dobyns, JH1
Bryan, RS1
Huet, PM1
Lelorier, J1
Scudds, RA1
Janzen, V1
Delaney, G1
Heck, C1
McCain, GA1
Russell, AL2
Teasell, RW1
Varkey, G1
Woodbury, GM1
Calvo, B1
Pedraz, JL1
Gascón, AR1
Hernández, RM1
García-Ortega, E1
Vara, F1
Muriel, C1
Domínguez-Gil, A1
Fazekas, T1
Scherlag, BJ1
Mabo, P1
Patterson, E1
Lazzara, R1
Schmidt, H1
Davis, A1
Stasche, N1
Hörmann, K1
Kaube, H1
Hoskin, KL1
Goadsby, PJ1
Ing, AJ1
Ngu, MC1
Breslin, AB1
Barnsley, L2
Lord, SM1
Wallis, BJ1
Bogduk, N2
Shiffman, ML2
Luketic, VA2
Sanyal, AJ2
Duckworth, PF1
Purdum, PP1
Contos, MJ1
Mills, AS1
Edinboro, LE1
Poklis, A1
Trochtenberg, S1
Stav, A1
Ovadia, L1
Sternberg, A1
Kaadan, M1
Weksler, N1
Lord, S1
Huang, YS1
Lee, SD1
Deng, JF1
Wu, JC1
Lu, RH1
Lin, YF1
Wang, YJ1
Lo, KJ1
Erickson, SJ1
Hogan, QH1
Bassøe, CF1
Opacić, M1
Rustemović, N1
Pulaníc, R1
Vucelić, B1
Frković, M1
Mandić, A1
Avidan, A1
Devor, M1
Glynn, C1
O'Sullivan, K1
Cappellino, A1
Jokl, P1
Ruwe, PA1
Condés-Lara, M1
Sánchez-Moreno, RM1
Omaña-Zapata, I1
Burdelski, M1
Schütz, E1
Nolte-Buchholtz, S1
Armstrong, VW1
Oellerich, M1
Thompson, EB1
Peterson, JN1
Schames, J1
Schames, M1
King, E1
Markey, BT1
Graham, M1
Tay, B1
Wallace, MS1
Irving, G1
Abraham, I1
Bacher, H1
Mischinger, HJ1
Werkgartner, G1
Cerwenka, H1
El-Shabrawi, A1
Pfeifer, J1
Schweiger, W1
Elin, RJ1
Fried, MW1
Sampson, M1
Ruddel, M1
Kleiner, DE1
DiBisceglie, AM1
Brox, JI1
Røe, C1
Saugen, E1
Vøllestad, NK1
Riedl, CR1
Knoll, M1
Plas, E1
Stephen, RL1
Pflüger, H1
Vickers, ER1
Cousins, MJ2
Walker, S1
Chisholm, K1
Rosanowski, F1
Hoppe, U1
Pröschel, U1
Eysholdt, U1
Jasmin, L1
Kohan, L1
Franssen, M1
Janni, G1
Goff, JR1
Garcia, J1
Roure, P1
Hayem, C1
Dupont, D1
Giannini, E1
Botta, F1
Fasoli, A1
Ceppa, P1
Risso, D1
Lantieri, PB1
Celle, G1
Testa, R1
Scrivani, SJ1
Chaudry, A1
Maciewicz, RJ1
Keith, DA1
Kupcová, V1
Turecký, L1
Szántová, M1
Schmidtová, K1
Yoshida, K1
Kaji, R1
Takagi, A1
Iizuka, T1
Wedi, B1
Novacovic, V1
Koerner, M1
Kapp, A1
Hand, PJ1
Stark, RJ1
Argov, S1
Levandovsky, O1
Cahana, A1
Shvelzon, V1
Dolberg, O1
Magora, F1
Shir, Y1
Okishige, K1
Nishizaki, M1
Azegami, K1
Igawa, M1
Yamawaki, N1
Aonuma, K1
Slipman, CW1
Lipetz, JS1
Plastaras, CT1
Jackson, HB1
Yang, ST1
Meyer, AM1
Tsukiyama, Y1
Baba, K1
Clark, GT1
Voltarelli, JC1
Ahmed, H1
Paton, EJ1
Stracieri, AB1
Holman, P1
Bashey, A1
Coutinho, M1
Simoes, BP1
Ball, ED1
Carrier, E1
Jacobi, PC1
Dietlein, TS1
Jacobi, FK1
Kellerhals, B1
Stymne, B1
Lillieborg, S1
Sato, T1
Mitamura, H1
Kurita, Y1
Takeshita, A1
Shinagawa, K1
Miyoshi, S1
Kanki, H1
Hara, M1
Ogawa, S1
Peleg, R1
Binyamin, L1
Smith, LJ1
Shih, A1
Miletic, G1
Miletic, V1
Woelk, C1
Benini, A1
Konrád, K1
Merétey, K1
Reviczky, LA1
Bozsóky, S1
Wolf, PS1
Goldberg, RT1
Prescott, LF4
Forrest, JA3
Adjepon-Yamoah, KK4
Finlayson, ND3
Salisbury, BG1
Metzger, LF1
Altose, MD1
Stanley, NN1
Cherniack, NS1
Bruxelle, J1
Marquez, C1
Giannakopoulos, X1
Champilomatos, P1
Wagaiyu, EG1
Chindia, ML1
Destache, CJ2
Hilleman, DE3
Mohiuddin, SJ1
Lang, PT1
Marchettini, P1
Lacerenza, M1
Marangoni, C1
Pellegata, G1
Smirne, S1
Mohiuddin, SM2
Mooss, AN2
Hunter, CB1
Sketch, MH2
Loubser, PG1
Donovan, WH1
Rubenstein, NH1
Ackerman, WE1
Colclough, GW1
Juneja, MM1
Bellinger, K1
Blumenkopf, B1
Lipman, JJ1
Crisologo, PA1
Neal, B1
Brown, R1
McDanal, J1
Kissin, I1
Hastings, RH1
McKay, WR1
O'Connor, M1
Brighouse, D1
Osborn, JW1
Taylor, RF1
Schramm, LP1
Gremse, DA1
A-Kader, HH1
Schroeder, TJ1
Balistreri, WF1
Petersen, P3
Kastrup, J3
Zeeberg, I1
Ellis, JS1
Ramamurthy, S1
Schoenfeld, LS1
Hoffman, J1
Walsh, NE1
Khamaganova, IV1
Angelo, H1
Dejgård, A2
Hilsted, J2
Esterbrooks, D1
Stengel, LA1
Butler, ML1
Cherry, DA1
Gourlay, GK1
McLachlan, M1
Kurgan, J1
Bourne, J1
de Langen, CD1
Hanich, RF1
Michelson, EL1
Kadish, AH1
Levine, JH1
Balke, CW1
Spear, JF1
Moore, EN1
Konsens, RM1
Seitz, WH1
Krasnowska, M1
Liebhart, E1
Małolepszy, J1
Angelo, HR1
Blevins, RD1
Kerin, NZ1
Mathias, P1
Pesola, D1
Faitel, K1
Jarandilla, R1
Garfinkel, C1
Rubenfire, M1
Vichi, FL1
Campos, IB1
Romero, LC1
Tukiyama, A1
Ball, GV1
Freeman, D1
Musini, A1
Fabbri, B1
Bergamaschi, M1
Mandelli, V1
Shanks, RG1
Nimmo, J1
Tiscornia, OM1
Palasciano, G1
Sarles, H1
Oliver, LP1
Rodriguez-Martinez, F1
Mascia, AV1
Mellins, RB1
Hunt, D1
Vohra, J1
Boussina, I1
Kuzmanovic, I1
Esselinckx, W1
Fallet, GH1
Porciello, PI1
Zanini, S1
Poppi, A1
Manheim, A1
Morgan, M1
Robson, JG1
Burn, JM1
Langdon, L1
Borisko, AS1
Chernobrovyĭ, NP1

Clinical Trials (23)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of Adrenaline Infiltration on Surgical Field of View in Endoscopic Sinus Surgery[NCT05867342]Phase 440 participants (Actual)Interventional2017-05-12Completed
The Effectiveness of Ultrasound Guided Sub-acromial Bursa Injection With Botulinum Toxin A in for Refractory Shoulder Pain After Stroke.[NCT02618603]Phase 450 participants (Anticipated)Interventional2016-02-29Not yet recruiting
Comparison of Percutaneous Diskectomy SpineJet x Open Microdiscectomy for Treatment of Lumbar Radiculopathy in Contained Disc Herniation: Randomized Clinical Trial[NCT01367860]40 participants (Actual)Interventional2011-06-30Completed
The Effect of Local Anesthesia With Lidocaine During Insertion and Removal of Nasal Packing[NCT04519463]Early Phase 160 participants (Anticipated)Interventional2020-09-30Not yet recruiting
Does the Use of Bupivacaine Soaked Vaginal Packing Following Vaginal Surgery Decrease Postoperative Pain?[NCT03266926]140 participants (Actual)Observational [Patient Registry]2017-02-01Completed
Comparative Evaluation of MEBO Ointment and Topical Diltiazem Ointment in the Treatment of Acute Anal Fissure: a Randomized Clinical Trial[NCT04153032]Phase 2183 participants (Anticipated)Interventional2019-12-01Recruiting
Effects of Platelet-rich Plasma in the Treatment of Chronic Anal Fissure[NCT04320498]Phase 441 participants (Actual)Interventional2019-01-01Completed
Brain Imaging of Lidoderm for Chronic Back Pain[NCT01515540]Phase 438 participants (Actual)Interventional2004-01-31Completed
Improvement of Motor Performance in Chronic Stroke Patients by Combined Transcranial DC Stimulation and Somatosensory Stimulation[NCT00110175]50 participants Observational2005-04-28Completed
Efficacy of Inhaled 50% Equimolar Nitrous Oxide/Oxygen Gas Premix (Kalinox®) as Compared to Topically Administered 5% Eutectic Mixture of Lidocaine/Prilocaine (EMLA®) in Chronic Leg Ulcer Debridement[NCT02696460]21 participants (Actual)Interventional2010-04-30Completed
Effectiveness of Corticosteroid vs Ketorolac Shoulder Injections: a Prospective Double-Blinded Randomized Trial[NCT04895280]Phase 4400 participants (Anticipated)Interventional2024-04-30Not yet recruiting
Effectiveness of Corticosteroid vs. Ketorolac Shoulder Injections: A Prospective Double-Blinded Randomized Trial[NCT04115644]Phase 482 participants (Actual)Interventional2017-05-01Terminated (stopped due to Covid-19 and we failed to submit annual report for 2017 and 2018)
Platelet Rich Plasma vs. Corticosteroid Injection in the Treatment of Partial Thickness Rotator Cuff Tears. A Randomized, Prospective, Double Blinded Trial.[NCT01688362]Phase 112 participants (Actual)Interventional2012-11-30Terminated (stopped due to Did not meet target enrollment deadlines.)
Effect of Intravenous Single-bolus Lidocaine Infusion Versus Intravenous Single-bolus Magnesium Sulfate Infusion on Postoperative Pain, Emotional Status and Quality of Life in Patients Undergoing Spine Fusion Surgery[NCT04776369]Phase 460 participants (Actual)Interventional2022-05-01Active, not recruiting
Assessment Of Pain Subsidence And Sexual Function Amelioration Using Either Pelvic Rehabilitation Or Trigger Point Injections[NCT02022722]Phase 436 participants (Anticipated)Interventional2013-08-31Recruiting
Double-blind, Prospective Comparison of Medications Used in Trigger Point Injections - Ketorolac, Lidocaine, or Dexamethasone[NCT03028012]Phase 410 participants (Actual)Interventional2017-05-02Terminated (stopped due to Poor enrollment.)
Do Cervical Interlaminar Epidural Steroid Injections With Low-dose Lidocaine Cause Transient Objective Upper Extremity Weakness? A Prospective Randomized Controlled Trial[NCT03127137]Phase 4123 participants (Actual)Interventional2018-08-01Completed
Do Cervical Interlaminar Epidural Steroid Injections With Low-dose Lidocaine Cause Transient Objective Upper Extremity Weakness? A Prospective Randomized[NCT03382925]Phase 416 participants (Actual)Interventional2017-12-20Terminated (stopped due to Not enough cervical interlaminar patients who meet criteria in order to meet recruitment goals.)
Rotator Cuff Tendinopathy: A Randomized and Blinded Comparison of Superficial and Deep Injection Methods[NCT01402011]77 participants (Actual)Interventional2010-11-30Completed
A Pilot Study Comparing Intra-articular Corticosteroid Injections to Platelet Rich Plasma (PRP) as a Treatment for Cervical Facetogenic Pain[NCT04392999]Phase 2/Phase 355 participants (Actual)Interventional2021-02-01Active, not recruiting
Development of a Breath Test for Monitoring Liver Metabolic Function in Patients With Chronic Liver Disease and Cirrhosis[NCT00244569]Phase 3120 participants (Anticipated)Interventional2005-09-30Completed
A Prospective Randomized Comparative Trial of Targeted Injection Via a Transforaminal Approach With Dexamethasone Versus an Epidural Catheter Via an Interlaminar Approach With Particulate Steroid for the Treatment of Cervical Radicular Pain[NCT03382821]Phase 4120 participants (Actual)Interventional2017-09-15Completed
The Efficacy of Intravenous Lidocaine Infusion in Chronic Unilateral Migraine Headache Clinical and Laboratory Assessment .Aprospective Randomized Double Blind Controlled Study[NCT06109389]Phase 280 participants (Actual)Interventional2023-10-01Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Duration of Surgery

(NCT05867342)
Timeframe: intraoperatively (up to 3 hours)

Interventionminutes (Mean)
1:1000 Epinephrine Plus Saline72.05
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine54.23

Estimated Blood Loss During Surgery

(NCT05867342)
Timeframe: intraoperatively (up to 3 hours)

InterventionmL (Mean)
1:1000 Epinephrine Plus Saline95.25
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine91.63

Number of Days With Postoperative Bloody Nasal Discharge

Participants indicated number of days with bloody nasal discharge postoperatively using the 1-week postoperative bleeding questionnaire. (NCT05867342)
Timeframe: 1 week after the surgery (up to 2 minutes to complete assessment)

Interventiondays (Mean)
1:1000 Epinephrine Plus Saline2.85
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine2.73

Number of Extra Pledgets Used

A pledget is a small wad of absorbent material used to stop bleeding. (NCT05867342)
Timeframe: intraoperatively (up to 3 hours)

Interventionpledgets (Mean)
1:1000 Epinephrine Plus Saline3.25
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine2.63

Number of Nostrils With Continuous Fresh Bleeding

Number of nostrils with excessive fresh bleeding postoperatively using the 1-week postoperative bleeding questionnaire. Continuous fresh bleeding was defined as bleeding for over 15 minutes. (NCT05867342)
Timeframe: 1 week after the surgery (up to 2 minutes to complete assessment)

Interventionnostrils (Count of Units)
1:1000 Epinephrine Plus Saline7
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine5

Postoperative Bloody Discharge Grading Score

Grading of postoperative bloody discharge postoperatively assessed by patient using the 1-week postoperative bleeding questionnaire. Scores range from 0 (no bleeding) to 5 (continuous heavy bleeding necessitating medical care). (NCT05867342)
Timeframe: 1 week after the surgery (up to 2 minutes to complete assessment)

Interventionscore on a scale (Mean)
1:1000 Epinephrine Plus Saline2.38
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine2.2

Surgical Field Grading Score

The video recording of the endoscopic sinus surgery of the participant was graded by another otolaryngology specialist postoperatively and graded according to Wormald Surgical Field Grading Scale. Scores range from 0 (no bleeding) to 10 (severe bleeding with nasal cavity filling rapidly). (NCT05867342)
Timeframe: postoperatively (approximately 20 minutes to assess)

Interventionscore on a scale (Mean)
1:1000 Epinephrine Plus Saline3.54
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine3.23

Oswestry Disability Index (ODI) - 12th Month

"Oswestry Disability Index (ODI) -> The Oswestry Disability Index (ODI) is one of the principal condition-specific outcome measures used in the management of spinal disorders. The ODI is the most commonly outcome measures in patients with low back pain.~Each of the 10 items is scored from 0 - 5. The maximum score is therefore 50. If the FIRST statement is marked, the section score = 0, If the LAST statement is marked, it = 5.~0 is the best outcome and 50 is the worst outcome." (NCT01367860)
Timeframe: 12th month from surgery

Interventionunits on a scale (Mean)
OMicro11
SJet12.7

Oswestry Disability Index (ODI) - 1st Month

"Oswestry Disability Index (ODI) -> The Oswestry Disability Index (ODI) is one of the principal condition-specific outcome measures used in the management of spinal disorders. The ODI is the most commonly outcome measures in patients with low back pain.~Each of the 10 items is scored from 0 - 5. The maximum score is therefore 50. If the FIRST statement is marked, the section score = 0, If the LAST statement is marked, it = 5.~0 is the best outcome and 50 is the worst outcome." (NCT01367860)
Timeframe: 1st month from baseline

Interventionunits on a scale (Mean)
OMicro19.25
SJet10.78

Oswestry Disability Index (ODI) - 1st Week

"Oswestry Disability Index (ODI) -> The Oswestry Disability Index (ODI) is one of the principal condition-specific outcome measures used in the management of spinal disorders. The ODI is the most commonly outcome measures in patients with low back pain.~Each of the 10 items is scored from 0 - 5. The maximum score is therefore 50. If the FIRST statement is marked, the section score = 0, If the LAST statement is marked, it = 5.~0 is the best outcome and 50 is the worst outcome." (NCT01367860)
Timeframe: 1st week minus baseline

Interventionunits on a scale (Mean)
OMicro23.25
SJet20

Oswestry Disability Index (ODI) - 3th Month

"Oswestry Disability Index (ODI) -> The Oswestry Disability Index (ODI) is one of the principal condition-specific outcome measures used in the management of spinal disorders. The ODI is the most commonly outcome measures in patients with low back pain.~Each of the 10 items is scored from 0 - 5. The maximum score is therefore 50. If the FIRST statement is marked, the section score = 0, If the LAST statement is marked, it = 5.~0 is the best outcome and 50 is the worst outcome." (NCT01367860)
Timeframe: 3th month

Interventionunits on a scale (Mean)
OMicro17.05
SJet16.85

Oswestry Disability Index (ODI) - 6th Month

"Oswestry Disability Index (ODI) -> The Oswestry Disability Index (ODI) is one of the principal condition-specific outcome measures used in the management of spinal disorders. The ODI is the most commonly outcome measures in patients with low back pain.~Each of the 10 items is scored from 0 - 5. The maximum score is therefore 50. If the FIRST statement is marked, the section score = 0, If the LAST statement is marked, it = 5.~0 is the best outcome and 50 is the worst outcome." (NCT01367860)
Timeframe: 6th month from surgery

Interventionunits on a scale (Mean)
OMicro15.37
SJet15.1

VAS for Leg Pain - 12th Month

pain scale - VAS for leg pain - 12th month (NCT01367860)
Timeframe: 12th month from surgery

Interventionunits on a scale (Mean)
OMicro3.37
SJet2.67

VAS for Leg Pain - 1st Month

Pain Score for leg pain - Visual Analog Scale (VAS) -> minimum value=0 and maximum value=10, higher values represent a worse outcome and zero is a better outcome. (NCT01367860)
Timeframe: 1st month from surgery

Interventionunits on a scale (Mean)
OMicro2.96
SJet2.76

VAS for Leg Pain - 1st Week

Pain Score for leg pain- Visual Analog Scale (VAS) -> minimum value=0 and maximum value=10, higher values represent a worse outcome and zero is a better outcome. (NCT01367860)
Timeframe: 1st week from surgery

Interventionunits on a scale (Mean)
OMicro4.3
SJet2.61

VAS for Leg Pain - 3rd Month

Pain Score for leg pain - Visual Analog Scale (VAS) -> minimum value=0 and maximum value=10, higher values represent a worse outcome and zero is a better outcome. (NCT01367860)
Timeframe: 3rd month from surgery

Interventionunits on a scale (Mean)
OMicro17.05
SJet16.85

VAS for Leg Pain - 6rd Month

Pain Score for leg pain - Visual Analog Scale (VAS) -> minimum value=0 and maximum value=10, higher values represent a worse outcome and zero is a better outcome. (NCT01367860)
Timeframe: 6th month from surgery

Interventionunits on a scale (Mean)
OMicro2.84
SJet2.88

VAS for Lumbar - 1st Week

Pain Score - Visual Analog Scale (VAS) -> minimum value=0 and maximum value=10, higher values represent a worse outcome and zero is a better outcome. (NCT01367860)
Timeframe: 1st week from surgery

Interventionunits on a scale (Mean)
OMicro3.71
SJet4.1

VAS for Lumbar 1st Month

Pain Score - Visual Analog Scale (VAS) -> minimum value=0 and maximum value=10, higher values represent a worse outcome and zero is a better outcome. (NCT01367860)
Timeframe: 1st month from surgery

Interventionunits on a scale (Mean)
OMicro3.34
SJet4.06

VAS for Lumbar Pain - 12th Month

Pain Score - Visual Analog Scale (VAS) -> minimum value=0 and maximum value=10, higher values represent a worse outcome and zero is a better outcome. (NCT01367860)
Timeframe: 12th month from surgery

Interventionunits on a scale (Mean)
OMicro4.06
SJet3.03

VAS for Lumbar Pain - 3rd Month

Pain Score - Visual Analog Scale (VAS) -> minimum value=0 and maximum value=10, higher values represent a worse outcome and zero is a better outcome. (NCT01367860)
Timeframe: 3rd month from surgery

Interventionunits on a scale (Mean)
OMicro2.63
SJet4.53

VAS for Lumbar Pain - 6th Month

Pain Score - Visual Analog Scale (VAS) -> minimum value=0 and maximum value=10, higher values represent a worse outcome and zero is a better outcome. (NCT01367860)
Timeframe: 6th month from surgery

Interventionunits on a scale (Mean)
OMicro3.5
SJet3.79

VAS for Lumbar Pain in 3 Months

Pain Score - Visual Analog Scale (VAS) -> minimum value=0 and maximum value=10, higher values represent a worse outcome and zero is a better outcome. (NCT01367860)
Timeframe: VAS for Lumbar Pain at 3 Months

Interventionunits on a scale (Mean)
OMicro2.63
SJet4.53

Clinical Evaluation

"Will be measured dichotomously: (present or absent)~Variables:~Infection; residual pain; herniation recurrency" (NCT01367860)
Timeframe: 6th month

,
Interventionparticipants (Number)
Infectionresidual painherniation recurrency
OMicro132
SJet141

"Pain Intensity on a Visual Analog Scale (VAS) The Scale Had Values From 0-100, Where 0 Represents no Pain and 100 Was the Worst Pain Imaginable."

"the primary hypothesis was that the lidoderm 5% patch was expected to decrease pain intensity post treatment greater than placebo patch.~A lower value on the 0-100 scale is considered to represent less pain. Higher values represent more pain. Greater than 20%-30% decrease in pain is considered clinically meaningful." (NCT01515540)
Timeframe: 2 weeks

Interventionpeak pain intensity (Mean)
Lidocaine51.0
Control51.6

Visual Analog Scale

Pain as measured by the Visual Analog Scale after first injection. The visual analog scale is a 0-10 scale, 0 being no pain, 10 being unbearable pain. (NCT04115644)
Timeframe: Baseline - immediately after the injection

Interventionscore on a scale (Mean)
Group 1 (Control)3.197
Group 2 (Ketorolac)3.577
Group 3 (Kenalog)3.677

Visual Analog Scale

Pain as measured by the Visual Analog Scale prior to first injection. The visual analog scale is a 0-10 scale, 0 being no pain, 10 being unbearable pain. (NCT04115644)
Timeframe: Baseline - pre-injection

Interventionscore on a scale (Mean)
Group 1 (Control)5.77
Group 2 (Ketorolac)4.57
Group 3 (Kenalog)4.67

Visual Analog Scale

Pain as measured by the Visual Analog Scale. The visual analog scale is a 0-10 scale, 0 being no pain, 10 being unbearable pain. (NCT04115644)
Timeframe: Day 2

Interventionscore on a scale (Mean)
Group 1 (Control)2.347
Group 2 (Ketorolac)2.837
Group 3 (Kenalog)2.67

Visual Analog Scale

Pain as measured by the Visual Analog Scale. The visual analog scale is a 0-10 scale, 0 being no pain, 10 being unbearable pain. (NCT04115644)
Timeframe: Week 1

Interventionscore on a scale (Mean)
Group 1 (Control)3.397
Group 2 (Ketorolac)3.7
Group 3 (Kenalog)3.257

Visual Analog Scale

Pain as measured by the Visual Analog Scale. The visual analog scale is a 0-10 scale, 0 being no pain, 10 being unbearable pain. (NCT04115644)
Timeframe: Week 12

Interventionscore on a scale (Mean)
Group 1 (Control)3.447
Group 2 (Ketorolac)1.417
Group 3 (Kenalog)2.027

Visual Analog Scale

Pain as measured by the Visual Analog Scale. The visual analog scale is a 0-10 scale, 0 being no pain, 10 being unbearable pain. (NCT04115644)
Timeframe: Week 2

Interventionscore on a scale (Mean)
Group 1 (Control)3.547
Group 2 (Ketorolac)2.67
Group 3 (Kenalog)2.57

Visual Analog Scale

Pain as measured by the Visual Analog Scale. The visual analog scale is a 0-10 scale, 0 being no pain, 10 being unbearable pain. (NCT04115644)
Timeframe: Week 4

Interventionscore on a scale (Mean)
Group 1 (Control)3.547
Group 2 (Ketorolac)2.67
Group 3 (Kenalog)2.317

Visual Analog Scale

Pain as measured by the Visual Analog Scale. The visual analog scale is a 0-10 scale, 0 being no pain, 10 being unbearable pain. (NCT04115644)
Timeframe: Week 6

Interventionscore on a scale (Mean)
Group 1 (Control)3.357
Group 2 (Ketorolac)2.757
Group 3 (Kenalog)2.687

Number of Participants With a Responder Rate Greater Than 50% on the Numeric Rating Pain Scale (NRS) Improvement

Participants in this study underwent TPIs by the following method. The needle was inserted into the trigger point with the goal of eliciting a local twitch responses(LTRs). When a LTR was obtained, 0.1mL of randomized drug was injected into that location within the muscle. This was repeated until LTRs disappeared, or 1.0mL had been injected, whichever came first. This was performed in a similar manner for all affected muscles, up to a maximum of 2mL. Participants self-report their brief pain inventory at each of their injections (up to four subsequent injections) based off of the standardized Numeric Rating pain Scale (NRS). The NRS is nationally recognized numeric scale from zero to ten, with zero being an example of no pain, one to three would demonstrate mild pain, four to six would be moderate pain, seven to nine would be severe pain and a ten would be the worst pain possible. Improvement in BPI was determined if their NRS score went down with each injection(s). (NCT03028012)
Timeframe: Pre-Post Injections Up to Three Months

InterventionParticipants (Count of Participants)
Ketorolac1
Lidocaine0
Dexamethasone0

Brief Pain Inventory (BPI) - Modified

The BPI was evaluated on a scale from 0-10. Zero would mean no interference and 10 would be calculated at complete interferences. We used a 7-point questionnaire about pain. All scores were calculated at baseline and three months. (NCT03028012)
Timeframe: Baseline and Three Months

Interventionscore on a scale (Number)
Participant Number #3 at BaselineParticipant Number #3 at 3 MonthsParticipant Number #8 at BaselineParticipant #8 at 3 Months
Ketorolac8353

Numeric Rating Pain Scale (NRS) at Baseline and Three Months.

TPI were treated with a needle inserted into the trigger point with the goal of eliciting a local twitch responses(LTRs). When a LTR was obtained, 0.1mL of randomized drug was injected into that location within the muscle. This was repeated until LTRs disappeared, or 1.0mL had been injected, whichever came first. Such was performed in a similar manner for all affected muscles, up to a maximum of 2mL. Participants self-report their brief pain inventory at each of their injections (up to four subsequent injections) based off of the standardized Numeric Rating pain Scale (NRS). The NRS is nationally recognized numeric scale from zero to ten, with zero being an example of no pain,one to three would demonstrate mild pain, four to six would be moderate pain, seven to nine would be severe pain and a ten would be the worst pain possible. Improvement in BPI was determined if their NRS score went down with each injection(s). (NCT03028012)
Timeframe: Pre-Injection and Three Month Post Injection(s)

Interventionscore on a scale (Number)
Participant Number 3 at BaselineParticipant Number 3 at 3 MonthsParticipant Number 8 at BaselineParticipant Number 8 at 3 Months
Ketorolac8353

Change in Strength in Both Groups After CESI.

Change in strength in both groups greater than or equal to 20% weakness in one or more myotomes 30 minutes after CESI using a hand held Dynamometer. (NCT03127137)
Timeframe: 30 minutes after the CESI procedure

,
InterventionParticipants (Count of Participants)
Yes, greater or equal to 20% weakness in greater or equal to 1 or more myotomeNo, greater or equal to 20% weakness in greater or equal to 1 or more myotome
Experimental Group 1 With Lidocaine2535
Experimental Group 2 With Saline3030

Change From Baseline in Maximum Pain Score at 9 Months

Participants were asked about pain at rest, at work, doing sports. The maximum pain reported on a scale ranging from 0 (no pain at all) to 10 (extreme pain) was recorded for each participant. Maximum of pain scores rest, work, sport recorded. Calculated as pain at baseline - pain at 9 months. (NCT01402011)
Timeframe: baseline and 9 months

Interventionunits on a scale (Mean)
25% Dextrose in Ligaments and Tendons2.9
.1% Lidocaine in Ligaments and Tendons1.8
.1% Lidocaine Subcutaneous1.3

Change From Baseline of Visual Analog Pain Scale at 3 Months

Subject marks his pain level at rest, at work, doing sports on a 10 cm scale. Maximum of pain scores rest, work, sport recorded. Calculated as pain at baseline - pain at 3 months. VAS scale is from 0 = no pain to 10 = maximum pain (NCT01402011)
Timeframe: baseline and three months

Interventionunits on a scale (Mean)
25% Dextrose in Ligaments and Tendons3.0
.1% Lidocaine in Ligaments and Tendons2.7
.1% Lidocaine Subcutaneous2.7

Nine Month Satisfaction Questionnaire

Phone call asking how satisfied were they with their treatment 10 = extremely satisfied, 0 = extremely dissatisfied ) (NCT01402011)
Timeframe: Nine months after first injection treatment appointment

Interventionunits on a scale (Mean)
25% Dextrose in Ligaments and Tendons6.7
.1% Lidocaine in Ligaments and Tendons4.7
.1% Lidocaine Subcutaneous3.9

Visual Analog Pain Scale 0= no Pain 10 = Maximum Pain

Subject marks his pain level at rest, at work, doing sports on a 10 cm scale. The maximum pain level among the 3 different activities was recorded. (NCT01402011)
Timeframe: 20 minutes before first injection on first day of patient visit

Interventionunits on a scale (Mean)
25% Dextrose in Shoulder Entheses7.3
.1% Lidocaine in Shoulder Entheses6.9
.1% Lidocaine Subcu. Above Shouldr Enth.6.9

Disabilities of the Arm Shoulder and Hand Questionnaire

http://www.dash.iwh.on.ca/assets/images/pdfs/DASH_quest06.pdf 30 questions assessing ability to use shoulder in everyday activities, each question scored 1 to 5, where one is normal, no problem and five is unable to perform. No data was collected at 9 months. The score ranges from 30 to 150. Higher scores represent worse outcomes. (NCT01402011)
Timeframe: 20 minutes before the first injection and at 3 months

,,
Interventionunits on a scale (Mean)
Baseline3 months
.1% Lidocaine in Ligaments and Tendons71.354.7
.1% Lidocaine Subcutaneous69.661
25% Dextrose in Ligaments and Tendons72.461.3

Physical Examination of the Shoulder Scale

From Steven W. Brose, DO, Michael L. Boninger, MD, Bradley Fullerton, MD, Thane McCann, MD, From: Jennifer L. Collinger, BSE, Bradley G. Impink, BSE, Trevor A. Dyson-Hudson, MD Shoulder ultrasound abnormalities, physical examination findings, and pain in manual wheelchair users with spinal cord injury. Arch Phys Med Rehabil 2008 Nov; 89:2086-93, appendix 1 12 parameters of shoulder examination: Biceps tendon/bicipital groove tenderness, Supraspinatus tendon/greater tuberosity tenderness Acromioclavicular joint tenderness Resisted external rotation. Resisted internal rotation. Supraspinatus test. Painful Arc Test. Neer impingement sign. Hawkins-Kennedy impingement sign. O'Brien Active Compression Test for AC Joint Pathology O'Brien Active Compression Test for Labral Pathology impingement sign. each test scored 0 = no pain, 1 = tenderness, 2 = pain. All 12 scores added. Range 0-24. Higher scores = more pathology (NCT01402011)
Timeframe: 20 minutes before first injection on first day of patient visit and at 3 months

,,
Interventionunits on a scale (Mean)
Baseline3 months
.1% Lidocaine in Ligaments and Tendons13.110.7
.1% Lidocaine Subcutaneous1312.9
25% Dextrose in Ligaments and Tendons13.211.4

Rotator Cuff Ultrasound, Ultrasound Shoulder Pathology Rating Scale

"From Brose et al. shoulder ultrasound abnormalities, physical examination findings, and pain in manual wheelchair users with spinal cord injury Arch Phys Med Rehabil 2008 Nov, 89: 2086-93 appendix 2. rates biceps tendinopathy (0-6), supraspinatus tendinopathy (0-5), greater tuberosity the cortical surface (0-3), dynamics supraspinatus impingement (0-3), dynamic subscapularis/ biceps/ coracoid impingement (0-3). The total score ranged from 0 to 20 with higher scores indicating a worse outcome. The change was calculated by taking the final score - the baseline score." (NCT01402011)
Timeframe: 20 minutes before first injection on first day of patient visit and at on average 9.4 months

,,
Interventionunits on a scale (Mean)
Baselinechange at 9.4 +/- 2.2 months
.1% Lidocaine in Ligaments and Tendons4.3-0.6
.1% Lidocaine Subcutaneous4.3-0.6
25% Dextrose in Ligaments and Tendons4.0-0.3

The Percentage of Participants With Reduction of 50% or More of Neck and Arm Pain NRS Score

The Percentage of Participants with Reduction of 50% or More of Neck and Arm Pain NRS score (NCT03382821)
Timeframe: 1 month follow up

Interventionpercentage of participants (Number)
Transforaminal ESI With Dexamethasone49.1
Interlaminar Catheter-targeted ESI With Triamcinolone68.5

"The Percentage of Participants Reporting Patient Global Impression of Change Score of 6-7 (Indicating Much Improved and Very Much Improved)"

"Patient Global Impression of Change is a scale which measures participant reported satisfaction after an intervention. The outcome was measured as the percent of patients reporting a PGIC score of 6-7 (indicating much improved and very much improved)" (NCT03382821)
Timeframe: 1 month, 3 month, 6 month, and 1 year follow up

,
Interventionpercentage of participants (Number)
One monthThree monthsSix monthsOne year
Transforaminal Catheter-targeted ESI With Triamcinolone59575361
Transforaminal ESI With Dexamethasone41425557

Neck Disability Index-5

Percentage of patients with >30% improvement in Neck Disability Index-5 score. (NCT03382821)
Timeframe: 1 month, 3 month, 6 month, and 1 year follow up

,
Interventionpercentage of participants (Number)
One monthThree monthSix monthOne year
Transforaminal Catheter-targeted ESI With Triamcinolone62585660
Transforaminal ESI With Dexamethasone48565547

Percentage of Participants Reporting >6.8 Reduction on the Medication Quantification Scale III

The Medication Quantification Scale (MQS) is an instrument used for clinical and research applications for quantifying medication regimen use in chronic pain populations. A 6.8 point reduction is considered equivalent to 10 morphine eqivalents. (NCT03382821)
Timeframe: 1 month, 3 month, 6 month, and 1 year follow up

,
Interventionpercentage of participants (Number)
One monthThree monthSix monthOne year
Transforaminal Catheter-targeted ESI With Triamcinolone1917198
Transforaminal ESI With Dexamethasone1620157

Reviews

23 reviews available for lidocaine and Chronic Illness

ArticleYear
Can Functional Nasal Surgery Treat Chronic Headaches? A Systematic Review.
    Plastic and reconstructive surgery, 2018, Volume: 142, Issue:6

    Topics: Anesthetics, Local; Chronic Disease; Endoscopy; Headache Disorders; Humans; Lidocaine; Pain Measurem

2018
The treatment of chronic recurrent oral aphthous ulcers.
    Deutsches Arzteblatt international, 2014, Oct-03, Volume: 111, Issue:40

    Topics: Adrenal Cortex Hormones; Anesthetics, Local; Anti-Infective Agents, Local; Anti-Inflammatory Agents;

2014
WITHDRAWN: Medicinal and injection therapies for mechanical neck disorders.
    The Cochrane database of systematic reviews, 2015, May-21, Issue:5

    Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Botulinum Toxins, Type A; Chronic Disea

2015
[Selection of drugs suitable for the treatment of intractable chronic pain patients by using drug challenge tests].
    Brain and nerve = Shinkei kenkyu no shinpo, 2008, Volume: 60, Issue:5

    Topics: Alprostadil; Analgesics; Barbiturates; Benzodiazepines; Chronic Disease; Humans; Ketamine; Lidocaine

2008
Recent advances in the pharmacotherapy of chronic anal fissure: an update.
    Asian journal of surgery, 2008, Volume: 31, Issue:3

    Topics: Administration, Topical; Adrenergic alpha-Antagonists; Anal Canal; Botulinum Toxins; Calcium Channel

2008
Recent advances in the pharmacotherapy of chronic anal fissure: an update.
    Asian journal of surgery, 2008, Volume: 31, Issue:3

    Topics: Administration, Topical; Adrenergic alpha-Antagonists; Anal Canal; Botulinum Toxins; Calcium Channel

2008
Recent advances in the pharmacotherapy of chronic anal fissure: an update.
    Asian journal of surgery, 2008, Volume: 31, Issue:3

    Topics: Administration, Topical; Adrenergic alpha-Antagonists; Anal Canal; Botulinum Toxins; Calcium Channel

2008
Recent advances in the pharmacotherapy of chronic anal fissure: an update.
    Asian journal of surgery, 2008, Volume: 31, Issue:3

    Topics: Administration, Topical; Adrenergic alpha-Antagonists; Anal Canal; Botulinum Toxins; Calcium Channel

2008
Practical management strategies for the chronic pain patient.
    The Journal of family practice, 2007, Volume: 56, Issue:8 Suppl Ho

    Topics: Administration, Cutaneous; Amines; Analgesics; Antidepressive Agents, Tricyclic; Carbamazepine; Chro

2007
[Mechanisms of the development of neuropathic pain and its treatment].
    Nihon Hansenbyo Gakkai zasshi = Japanese journal of leprosy : official organ of the Japanese Leprosy Association, 2008, Volume: 77, Issue:3

    Topics: Amines; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents, Tricyclic; Calcium Channel Block

2008
Intravenous infusion tests have limited utility for selecting long-term drug therapy in patients with chronic pain: a systematic review.
    Anesthesiology, 2009, Volume: 111, Issue:2

    Topics: Adrenergic alpha-Antagonists; Analgesics, Opioid; Anesthetics, Dissociative; Anesthetics, Local; Chr

2009
Management of chronic noncancer pain in depressed patients.
    Postgraduate medicine, 2011, Volume: 123, Issue:5

    Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, N

2011
Nonopioid and adjuvant analgesics in chronic pain management: strategies for effective use.
    The Nursing clinics of North America, 2003, Volume: 38, Issue:3

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal

2003
Diagnosis and management of neuropathic pain: a balanced approach to treatment.
    Journal of the American Academy of Nurse Practitioners, 2003, Volume: 15, Issue:12 Suppl

    Topics: Acetates; Amines; Antidepressive Agents; Chronic Disease; Cyclohexanecarboxylic Acids; Gabapentin; g

2003
[Recognition and treatment of neuropathic pain].
    Duodecim; laaketieteellinen aikakauskirja, 2004, Volume: 120, Issue:2

    Topics: Analgesics, Opioid; Chronic Disease; Depressive Disorder; Drug Therapy, Combination; Epilepsy; Femal

2004
Prolotherapy injections for chronic low-back pain.
    The Cochrane database of systematic reviews, 2004, Issue:2

    Topics: Chronic Disease; Combined Modality Therapy; Exercise Therapy; Glucose; Glycerol; Humans; Injections;

2004
Medicinal and injection therapies for mechanical neck disorders.
    The Cochrane database of systematic reviews, 2005, Apr-18, Issue:2

    Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Humans; Lidocaine; Met

2005
A systematic review of prolotherapy for chronic musculoskeletal pain.
    Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine, 2005, Volume: 15, Issue:5

    Topics: Anesthetics, Local; Chronic Disease; Glucose; Humans; Injections; Lidocaine; Low Back Pain; Musculos

2005
The role of sodium channels in chronic inflammatory and neuropathic pain.
    The journal of pain, 2006, Volume: 7, Issue:5 Suppl 3

    Topics: Anesthetics, Local; Calcium Signaling; Chronic Disease; Humans; Inflammation; Lidocaine; Nervous Sys

2006
Commentary on peripheral and central contributions to hyperalgesia in irritable bowel syndrome.
    The journal of pain, 2006, Volume: 7, Issue:8

    Topics: Administration, Rectal; Anesthetics, Local; Central Nervous System; Chronic Disease; Humans; Hyperal

2006
Adjuvant analgesics for the treatment of neuropathic pain: evaluating efficacy and safety profiles.
    The Journal of family practice, 2007, Volume: 56, Issue:2 Suppl Pa

    Topics: Administration, Cutaneous; Amines; Analgesics; Analgesics, Opioid; Antidepressive Agents; Arthritis;

2007
Prolotherapy injections for chronic low-back pain.
    The Cochrane database of systematic reviews, 2007, Apr-18, Issue:2

    Topics: Chronic Disease; Combined Modality Therapy; Exercise Therapy; Glucose; Glycerol; Humans; Injections;

2007
Medicinal and injection therapies for mechanical neck disorders.
    The Cochrane database of systematic reviews, 2007, Jul-18, Issue:3

    Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Botulinum Toxins, Type A; Chronic Disea

2007
Medicinal and injection therapies for mechanical neck disorders.
    The Cochrane database of systematic reviews, 2007, Jul-18, Issue:3

    Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Botulinum Toxins, Type A; Chronic Disea

2007
Medicinal and injection therapies for mechanical neck disorders.
    The Cochrane database of systematic reviews, 2007, Jul-18, Issue:3

    Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Botulinum Toxins, Type A; Chronic Disea

2007
Medicinal and injection therapies for mechanical neck disorders.
    The Cochrane database of systematic reviews, 2007, Jul-18, Issue:3

    Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Botulinum Toxins, Type A; Chronic Disea

2007
Medicinal and injection therapies for mechanical neck disorders.
    The Cochrane database of systematic reviews, 2007, Jul-18, Issue:3

    Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Botulinum Toxins, Type A; Chronic Disea

2007
Medicinal and injection therapies for mechanical neck disorders.
    The Cochrane database of systematic reviews, 2007, Jul-18, Issue:3

    Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Botulinum Toxins, Type A; Chronic Disea

2007
Medicinal and injection therapies for mechanical neck disorders.
    The Cochrane database of systematic reviews, 2007, Jul-18, Issue:3

    Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Botulinum Toxins, Type A; Chronic Disea

2007
Medicinal and injection therapies for mechanical neck disorders.
    The Cochrane database of systematic reviews, 2007, Jul-18, Issue:3

    Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Botulinum Toxins, Type A; Chronic Disea

2007
Medicinal and injection therapies for mechanical neck disorders.
    The Cochrane database of systematic reviews, 2007, Jul-18, Issue:3

    Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Botulinum Toxins, Type A; Chronic Disea

2007
An evidence-based assessment of occlusal adjustment as a treatment for temporomandibular disorders.
    The Journal of prosthetic dentistry, 2001, Volume: 86, Issue:1

    Topics: Adult; Anesthetics, Local; Anti-Inflammatory Agents; Betamethasone; Biofeedback, Psychology; Bruxism

2001
Drug metabolism in liver disease.
    Journal of clinical pathology. Supplement (Royal College of Pathologists), 1975, Volume: 9

    Topics: Acetaminophen; Acute Disease; Antipyrine; Chemical and Drug Induced Liver Injury; Chronic Disease; H

1975
Behçet's syndrome presenting with chronic periodontitis: a case report.
    East African medical journal, 1992, Volume: 69, Issue:10

    Topics: Behcet Syndrome; Carboxymethylcellulose Sodium; Chronic Disease; Female; Hospitals, University; Huma

1992

Trials

58 trials available for lidocaine and Chronic Illness

ArticleYear
The effect of topical epinephrine 1:1000 with and without infiltration of 1% lidocaine with epinephrine 1:100,000 on endoscopic surgical field visualization: a double-blind randomized controlled study.
    International forum of allergy & rhinology, 2020, Volume: 10, Issue:2

    Topics: Administration, Topical; Adult; Aged; Anesthetics, Local; Blood Loss, Surgical; Chronic Disease; Dou

2020
Effect of Dextrose Prolotherapy on Pain Intensity, Disability, and Plantar Fascia Thickness in Unilateral Plantar Fasciitis: A Randomized, Controlled, Double-Blind Study.
    American journal of physical medicine & rehabilitation, 2020, Volume: 99, Issue:4

    Topics: Adult; Chronic Disease; Disability Evaluation; Double-Blind Method; Fasciitis, Plantar; Female; Gluc

2020
The Effectiveness of EMLA as a Primary Dressing on Painful Chronic Leg Ulcers: Effects on Wound Healing and Health-Related Quality of Life.
    The international journal of lower extremity wounds, 2017, Volume: 16, Issue:3

    Topics: Aged; Aged, 80 and over; Australia; Chronic Disease; Cross-Over Studies; Female; Follow-Up Studies;

2017
No beneficial effect of Polidocanol treatment in Achilles tendinopathy: a randomised controlled trial.
    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2018, Volume: 26, Issue:7

    Topics: Achilles Tendon; Adult; Aged; Anesthetics, Local; Chronic Disease; Exercise; Female; Humans; Injecti

2018
Effectiveness of surgical treatment in chronic migraine.
    Cirugia y cirujanos, 2018, Volume: 86, Issue:1

    Topics: Adolescent; Adult; Chronic Disease; Decompression, Surgical; Facial Muscles; Female; Humans; Lidocai

2018
The Role of Endoscopic Sphenopalatine Ganglion Block on Nausea and Vomiting After Sinus Surgery.
    American journal of rhinology & allergy, 2018, Volume: 32, Issue:5

    Topics: Adult; Anesthesia, General; Chronic Disease; Double-Blind Method; Drug Combinations; Endoscopy; Epin

2018
Is ultrasound-guided injection more effective in chronic subacromial bursitis?
    Medicine and science in sports and exercise, 2013, Volume: 45, Issue:12

    Topics: Adult; Aged; Anesthetics, Local; Bursitis; Chronic Disease; Female; Humans; Injections, Intra-Articu

2013
Autologous platelet-rich plasma versus dextrose prolotherapy for the treatment of chronic recalcitrant plantar fasciitis.
    PM & R : the journal of injury, function, and rehabilitation, 2014, Volume: 6, Issue:2

    Topics: Adult; Anesthetics, Local; Chronic Disease; Disability Evaluation; Fasciitis, Plantar; Female; Gluco

2014
Controlled medial branch anesthetic block in the diagnosis of chronic lumbar facet joint pain: the value of a three-month follow-up.
    Clinics (Sao Paulo, Brazil), 2014, Volume: 69, Issue:8

    Topics: Adult; Age Factors; Aged; Anesthetics, Local; Brazil; Chronic Disease; False Positive Reactions; Fem

2014
Does pterygopalatine canal injection with local anaesthetic and adrenaline decrease bleeding during functional endoscopic sinus surgery?
    The Journal of laryngology and otology, 2014, Volume: 128, Issue:9

    Topics: Adult; Aged; Anesthetics, Local; Blood Loss, Surgical; Chronic Disease; Epinephrine; Epistaxis; Fema

2014
Different anesthetic agents-soaked sinus packings on pain management after functional endoscopic sinus surgery: which is the most effective?
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2016, Volume: 273, Issue:7

    Topics: Adolescent; Adult; Amides; Anesthetics, Local; Bandages; Bupivacaine; Chronic Disease; Endoscopy; Fe

2016
Different anesthetic agents-soaked sinus packings on pain management after functional endoscopic sinus surgery: which is the most effective?
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2016, Volume: 273, Issue:7

    Topics: Adolescent; Adult; Amides; Anesthetics, Local; Bandages; Bupivacaine; Chronic Disease; Endoscopy; Fe

2016
Different anesthetic agents-soaked sinus packings on pain management after functional endoscopic sinus surgery: which is the most effective?
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2016, Volume: 273, Issue:7

    Topics: Adolescent; Adult; Amides; Anesthetics, Local; Bandages; Bupivacaine; Chronic Disease; Endoscopy; Fe

2016
Different anesthetic agents-soaked sinus packings on pain management after functional endoscopic sinus surgery: which is the most effective?
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2016, Volume: 273, Issue:7

    Topics: Adolescent; Adult; Amides; Anesthetics, Local; Bandages; Bupivacaine; Chronic Disease; Endoscopy; Fe

2016
Antitussive effect of carcainium chloride in patients with chronic cough and idiopathic interstitial pneumonias: A pilot study.
    Pulmonary pharmacology & therapeutics, 2016, Volume: 40

    Topics: Administration, Inhalation; Aerosols; Aged; Anesthetics, Local; Antitussive Agents; Chronic Disease;

2016
The efficacy of the AMPA receptor antagonist NS1209 and lidocaine in nerve injury pain: a randomized, double-blind, placebo-controlled, three-way crossover study.
    Anesthesia and analgesia, 2009, Volume: 108, Issue:4

    Topics: Adult; Aged; Analgesia; Anesthetics, Local; Chronic Disease; Cross-Over Studies; Double-Blind Method

2009
Perioperative intravenous lidocaine decreases the incidence of persistent pain after breast surgery.
    The Clinical journal of pain, 2012, Volume: 28, Issue:7

    Topics: Administration, Intravenous; Adult; Aged; Anesthetics, Local; Back Pain; Breast Neoplasms; Chronic D

2012
Comparison of ropivacaine, bupivacaine and lidocaine in the management of post-tonsillectomy pain.
    International journal of pediatric otorhinolaryngology, 2012, Volume: 76, Issue:12

    Topics: Adenoidectomy; Administration, Topical; Adolescent; Age Factors; Amides; Anesthetics, Local; Blood L

2012
Usefulness of a myofascial trigger point injection for groin pain in patients with chronic prostatitis/chronic pelvic pain syndrome: a pilot study.
    Archives of physical medicine and rehabilitation, 2013, Volume: 94, Issue:5

    Topics: Abdominal Muscles; Adult; Anesthetics, Local; Chronic Disease; Humans; Injections, Intramuscular; Li

2013
Improving hand function in chronic stroke.
    Archives of neurology, 2002, Volume: 59, Issue:8

    Topics: Afferent Pathways; Anesthetics, Local; Brachial Plexus; Chronic Disease; Electric Stimulation Therap

2002
Magnesium Bier's block for treatment of chronic limb pain: a randomised, double-blind, cross-over study.
    Pain, 2002, Volume: 99, Issue:1-2

    Topics: Adult; Aged; Aged, 80 and over; Analgesics; Anesthetics, Local; Autonomic Nerve Block; Chronic Disea

2002
Topical nifedipine with lidocaine ointment vs. active control for treatment of chronic anal fissure: results of a prospective, randomized, double-blind study.
    Diseases of the colon and rectum, 2002, Volume: 45, Issue:11

    Topics: Administration, Topical; Adolescent; Adult; Aged; Chronic Disease; Double-Blind Method; Drug Combina

2002
Using a topical anaesthetic cream to reduce pain during sharp debridement of chronic leg ulcers.
    Journal of wound care, 2001, Volume: 10, Issue:1

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Chronic Disease; Debr

2001
Lidocaine patch 5% with systemic analgesics such as gabapentin: a rational polypharmacy approach for the treatment of chronic pain.
    Pain medicine (Malden, Mass.), 2003, Volume: 4, Issue:4

    Topics: Acetates; Activities of Daily Living; Aged; Aged, 80 and over; Amines; Analgesics; Anesthetics, Loca

2003
[Use of the round window micro cath for inner ear therapy - results of a placebo-controlled, prospective study on chronic tinnitus].
    Laryngo- rhino- otologie, 2004, Volume: 83, Issue:3

    Topics: Administration, Topical; Adult; Aged; Auditory Threshold; Catheters, Indwelling; Chronic Disease; Ea

2004
Effects of antiarrhythmic agents on left ventricular function during exercise in patients with chronic left ventricular dysfunction.
    Annals of nuclear medicine, 2004, Volume: 18, Issue:3

    Topics: Aged; Anti-Asthmatic Agents; Chronic Disease; Disopyramide; Exercise; Exercise Test; Female; Heart V

2004
Effectiveness of the lidocaine patch 5% on pain qualities in three chronic pain states: assessment with the Neuropathic Pain Scale.
    Current medical research and opinion, 2004, Volume: 20 Suppl 2

    Topics: Administration, Cutaneous; Aged; Anesthetics, Local; Chronic Disease; Diabetic Neuropathies; Female;

2004
Comparison of caudal steroid epidural with targeted steroid placement during spinal endoscopy for chronic sciatica: a prospective, randomized, double-blind trial.
    British journal of anaesthesia, 2005, Volume: 94, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anti-Inflammatory Agents; Chronic Disease; Doubl

2005
A prospective, double-blind, randomized clinical trial comparing subacromial injection of betamethasone and xylocaine to xylocaine alone in chronic rotator cuff tendinosis.
    The American journal of sports medicine, 2005, Volume: 33, Issue:2

    Topics: Anesthetics, Local; Betamethasone; Chronic Disease; Glucocorticoids; Humans; Injections, Intralesion

2005
A prospective, double-blind, randomized clinical trial comparing subacromial injection of betamethasone and xylocaine to xylocaine alone in chronic rotator cuff tendinosis.
    The American journal of sports medicine, 2005, Volume: 33, Issue:2

    Topics: Anesthetics, Local; Betamethasone; Chronic Disease; Glucocorticoids; Humans; Injections, Intralesion

2005
A prospective, double-blind, randomized clinical trial comparing subacromial injection of betamethasone and xylocaine to xylocaine alone in chronic rotator cuff tendinosis.
    The American journal of sports medicine, 2005, Volume: 33, Issue:2

    Topics: Anesthetics, Local; Betamethasone; Chronic Disease; Glucocorticoids; Humans; Injections, Intralesion

2005
A prospective, double-blind, randomized clinical trial comparing subacromial injection of betamethasone and xylocaine to xylocaine alone in chronic rotator cuff tendinosis.
    The American journal of sports medicine, 2005, Volume: 33, Issue:2

    Topics: Anesthetics, Local; Betamethasone; Chronic Disease; Glucocorticoids; Humans; Injections, Intralesion

2005
A prospective, double-blind, randomized clinical trial comparing subacromial injection of betamethasone and xylocaine to xylocaine alone in chronic rotator cuff tendinosis.
    The American journal of sports medicine, 2005, Volume: 33, Issue:2

    Topics: Anesthetics, Local; Betamethasone; Chronic Disease; Glucocorticoids; Humans; Injections, Intralesion

2005
A prospective, double-blind, randomized clinical trial comparing subacromial injection of betamethasone and xylocaine to xylocaine alone in chronic rotator cuff tendinosis.
    The American journal of sports medicine, 2005, Volume: 33, Issue:2

    Topics: Anesthetics, Local; Betamethasone; Chronic Disease; Glucocorticoids; Humans; Injections, Intralesion

2005
A prospective, double-blind, randomized clinical trial comparing subacromial injection of betamethasone and xylocaine to xylocaine alone in chronic rotator cuff tendinosis.
    The American journal of sports medicine, 2005, Volume: 33, Issue:2

    Topics: Anesthetics, Local; Betamethasone; Chronic Disease; Glucocorticoids; Humans; Injections, Intralesion

2005
A prospective, double-blind, randomized clinical trial comparing subacromial injection of betamethasone and xylocaine to xylocaine alone in chronic rotator cuff tendinosis.
    The American journal of sports medicine, 2005, Volume: 33, Issue:2

    Topics: Anesthetics, Local; Betamethasone; Chronic Disease; Glucocorticoids; Humans; Injections, Intralesion

2005
A prospective, double-blind, randomized clinical trial comparing subacromial injection of betamethasone and xylocaine to xylocaine alone in chronic rotator cuff tendinosis.
    The American journal of sports medicine, 2005, Volume: 33, Issue:2

    Topics: Anesthetics, Local; Betamethasone; Chronic Disease; Glucocorticoids; Humans; Injections, Intralesion

2005
Lumbar zygapophyseal joint injections in patients with chronic lower back pain.
    Journal of the Chinese Medical Association : JCMA, 2005, Volume: 68, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arthrography; Betamethasone; Chronic Disease; Drug Combi

2005
Efficacy of lidocaine in the treatment of pruritus in patients with chronic cholestatic liver diseases.
    The American journal of medicine, 2005, Volume: 118, Issue:10

    Topics: Adult; Aged; Cholangitis, Sclerosing; Cholestasis; Chronic Disease; Double-Blind Method; Drug Resist

2005
Do diagnostic segmental nerve root blocks in chronic low back pain patients with radiation to the leg lack distinct sensory effects? A preliminary study.
    British journal of anaesthesia, 2006, Volume: 96, Issue:2

    Topics: Adult; Amides; Anesthetics, Local; Chronic Disease; Electric Stimulation; Epidemiologic Methods; Fem

2006
Levator ani trigger point injections: An underutilized treatment for chronic pelvic pain.
    Neurourology and urodynamics, 2007, Volume: 26, Issue:1

    Topics: Adult; Aged; Anesthetics, Local; Anti-Inflammatory Agents; Anus Diseases; Bupivacaine; Chronic Disea

2007
Case series on chronic whiplash related neck pain treated with intraarticular zygapophysial joint regeneration injection therapy.
    Pain physician, 2007, Volume: 10, Issue:2

    Topics: Adult; Anesthetics, Local; Cervical Vertebrae; Chronic Disease; Disability Evaluation; Female; Follo

2007
[Antiarrhythmic drugs in chronic ventricular extrasystole (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1980, Feb-08, Volume: 105, Issue:6

    Topics: 17-Ketosteroids; Adult; Aged; Ajmaline; Androstanols; Anti-Arrhythmia Agents; Cardiac Complexes, Pre

1980
The use of topical 4% lidocaine in spheno-palatine ganglion blocks for the treatment of chronic muscle pain syndromes: a randomized, controlled trial.
    Pain, 1995, Volume: 62, Issue:1

    Topics: Administration, Topical; Adult; Anxiety; Autonomic Nerve Block; Chronic Disease; Depression; Double-

1995
The influence of adrenalin on the pharmacokinetics of interpleurally administered lidocaine in patients with pancreatic neoplasia.
    Journal of clinical pharmacology, 1995, Volume: 35, Issue:4

    Topics: Absorption; Adult; Analgesia; Chronic Disease; Epinephrine; Female; Half-Life; Humans; Lidocaine; Ma

1995
Pathogenesis of chronic persistent cough associated with gastroesophageal reflux.
    American journal of respiratory and critical care medicine, 1994, Volume: 149, Issue:1

    Topics: Adult; Afferent Pathways; Chronic Disease; Cough; Double-Blind Method; Efferent Pathways; Esophagus;

1994
Lack of effect of intraarticular corticosteroids for chronic pain in the cervical zygapophyseal joints.
    The New England journal of medicine, 1994, Apr-14, Volume: 330, Issue:15

    Topics: Adult; Anesthetics, Local; Betamethasone; Bupivacaine; Cervical Vertebrae; Chronic Disease; Double-B

1994
Cervical epidural steroid injection for cervicobrachialgia.
    Acta anaesthesiologica Scandinavica, 1993, Volume: 37, Issue:6

    Topics: Adult; Aged; Analgesia, Epidural; Brachial Plexus Neuritis; Cervical Vertebrae; Chronic Disease; Dru

1993
Cervical epidural steroid injection for cervicobrachialgia.
    Acta anaesthesiologica Scandinavica, 1993, Volume: 37, Issue:6

    Topics: Adult; Aged; Analgesia, Epidural; Brachial Plexus Neuritis; Cervical Vertebrae; Chronic Disease; Dru

1993
Cervical epidural steroid injection for cervicobrachialgia.
    Acta anaesthesiologica Scandinavica, 1993, Volume: 37, Issue:6

    Topics: Adult; Aged; Analgesia, Epidural; Brachial Plexus Neuritis; Cervical Vertebrae; Chronic Disease; Dru

1993
Cervical epidural steroid injection for cervicobrachialgia.
    Acta anaesthesiologica Scandinavica, 1993, Volume: 37, Issue:6

    Topics: Adult; Aged; Analgesia, Epidural; Brachial Plexus Neuritis; Cervical Vertebrae; Chronic Disease; Dru

1993
Cervical epidural steroid injection for cervicobrachialgia.
    Acta anaesthesiologica Scandinavica, 1993, Volume: 37, Issue:6

    Topics: Adult; Aged; Analgesia, Epidural; Brachial Plexus Neuritis; Cervical Vertebrae; Chronic Disease; Dru

1993
Cervical epidural steroid injection for cervicobrachialgia.
    Acta anaesthesiologica Scandinavica, 1993, Volume: 37, Issue:6

    Topics: Adult; Aged; Analgesia, Epidural; Brachial Plexus Neuritis; Cervical Vertebrae; Chronic Disease; Dru

1993
Cervical epidural steroid injection for cervicobrachialgia.
    Acta anaesthesiologica Scandinavica, 1993, Volume: 37, Issue:6

    Topics: Adult; Aged; Analgesia, Epidural; Brachial Plexus Neuritis; Cervical Vertebrae; Chronic Disease; Dru

1993
Cervical epidural steroid injection for cervicobrachialgia.
    Acta anaesthesiologica Scandinavica, 1993, Volume: 37, Issue:6

    Topics: Adult; Aged; Analgesia, Epidural; Brachial Plexus Neuritis; Cervical Vertebrae; Chronic Disease; Dru

1993
Cervical epidural steroid injection for cervicobrachialgia.
    Acta anaesthesiologica Scandinavica, 1993, Volume: 37, Issue:6

    Topics: Adult; Aged; Analgesia, Epidural; Brachial Plexus Neuritis; Cervical Vertebrae; Chronic Disease; Dru

1993
Comparative local anaesthetic blocks in the diagnosis of cervical zygapophysial joint pain.
    Pain, 1993, Volume: 55, Issue:1

    Topics: Adult; Aged; Anesthetics, Local; Arthrography; Bupivacaine; Cervical Vertebrae; Chronic Disease; Dou

1993
Measuring lidocaine metabolite--monoethylglycinexylidide as a quantitative index of hepatic function in adults with chronic hepatitis and cirrhosis.
    Journal of hepatology, 1993, Volume: 19, Issue:1

    Topics: Adult; Chronic Disease; Female; Follow-Up Studies; Galactose; Hepatitis; Humans; Indocyanine Green;

1993
A double-blind randomised comparison of the effects of epidural clonidine, lignocaine and the combination of clonidine and lignocaine in patients with chronic pain.
    Pain, 1996, Volume: 64, Issue:2

    Topics: Adrenergic alpha-Agonists; Adult; Aged; Analgesia, Epidural; Anesthetics, Local; Chronic Disease; Cl

1996
Quantitative assessment of differential sensory blockade after lumbar epidural lidocaine.
    Anesthesia and analgesia, 1997, Volume: 84, Issue:5

    Topics: Adult; Anesthesia, Epidural; Anesthetics, Local; Chronic Disease; Cold Temperature; Electric Stimula

1997
Local nitroglycerin for treatment of anal fissures: an alternative to lateral sphincterotomy?
    Diseases of the colon and rectum, 1997, Volume: 40, Issue:7

    Topics: Acute Disease; Administration, Rectal; Administration, Topical; Adult; Anal Canal; Anesthetics, Loca

1997
Isometric abduction muscle activation in patients with rotator tendinosis of the shoulder.
    Archives of physical medicine and rehabilitation, 1997, Volume: 78, Issue:11

    Topics: Adult; Anesthetics, Local; Bupivacaine; Chronic Disease; Electromyography; Female; Humans; Isometric

1997
Analysis of 50 patients with atypical odontalgia. A preliminary report on pharmacological procedures for diagnosis and treatment.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 1998, Volume: 85, Issue:1

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anesthetics, Combined; Anesthetics, Local;

1998
[Bronchial endoscopy under local anesthesia and pain in children. The value of a nitrous oxide-oxygen combination].
    Revue des maladies respiratoires, 1998, Volume: 15, Issue:2

    Topics: Adjuvants, Anesthesia; Administration, Rectal; Anesthesia, Local; Anesthetics, Inhalation; Anestheti

1998
Chronic neurogenic facial pain: lack of response to intravenous phentolamine.
    Journal of orofacial pain, 1999,Spring, Volume: 13, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Anesthetics, Local; Causalgia; Chronic Disease; Facial Pa

1999
[Intravenous lignocaine for chronic pain: an 18-month experience].
    Harefuah, 1998, May-01, Volume: 134, Issue:9

    Topics: Adult; Aged; Anesthetics, Local; Blood Pressure; Chronic Disease; Female; Heart Rate; Humans; Infusi

1998
Pilsicainide for conversion and maintenance of sinus rhythm in chronic atrial fibrillation: a placebo-controlled, multicenter study.
    American heart journal, 2000, Volume: 140, Issue:3

    Topics: Administration, Oral; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Chronic Disease; Drug Admin

2000
Cataract surgery under topical anesthesia in patients with coexisting glaucoma.
    Journal of cataract and refractive surgery, 2001, Volume: 27, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Cataract; Chronic Disease; Fe

2001
Plasma concentrations of lignocaine and prilocaine after a 24-h application of analgesic cream (EMLA) to leg ulcers.
    The British journal of dermatology, 2001, Volume: 145, Issue:4

    Topics: Aged; Aged, 80 and over; Anesthetics, Combined; Anesthetics, Local; Chronic Disease; Dose-Response R

2001
Lidocaine test in neuralgia.
    Pain, 1992, Volume: 48, Issue:3

    Topics: Adolescent; Adult; Aged; Blood Pressure; Chronic Disease; Electrocardiography; Female; Humans; Lidoc

1992
Diagnostic spinal anaesthesia in chronic spinal cord injury pain.
    Paraplegia, 1991, Volume: 29, Issue:1

    Topics: Adolescent; Adult; Anesthesia, Spinal; Chronic Disease; Dose-Response Relationship, Drug; Female; Hu

1991
[Intravenous lidocaine in the treatment of chronic pain].
    Ugeskrift for laeger, 1986, Aug-18, Volume: 148, Issue:34

    Topics: Adult; Aged; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Injecti

1986
Treatment of chronic painful diabetic neuropathy with intravenous lidocaine infusion.
    British medical journal (Clinical research ed.), 1986, Jan-18, Volume: 292, Issue:6514

    Topics: Adult; Chronic Disease; Clinical Trials as Topic; Diabetic Neuropathies; Double-Blind Method; Female

1986
Double-blind randomized comparison of intravenous tocainide versus lidocaine in the treatment of chronic ventricular arrhythmias.
    American heart journal, 1987, Volume: 114, Issue:2

    Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chronic Disease; Clinical Trials as Topic; Double-Blin

1987
[Possibility of prevention of histamine-induced bronchospastic reaction with fenoterol, ipratropium bromide and lidocaine in patients with chronic bronchitis].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1985, Feb-04, Volume: 40, Issue:5

    Topics: Adult; Aerosols; Aged; Atropine Derivatives; Bronchial Spasm; Bronchitis; Chronic Disease; Clinical

1985
Intravenous lidocaine infusion--a new treatment of chronic painful diabetic neuropathy?
    Pain, 1987, Volume: 28, Issue:1

    Topics: Adult; Chronic Disease; Diabetic Neuropathies; Double-Blind Method; Female; Humans; Infusions, Intra

1987
Intravenous lorcainide versus lidocaine in the treatment of frequent and complex ventricular arrhythmias.
    American heart journal, 1986, Volume: 111, Issue:3

    Topics: Aged; Arrhythmias, Cardiac; Benzeneacetamides; Chronic Disease; Electrocardiography; Female; Humans;

1986

Other Studies

135 other studies available for lidocaine and Chronic Illness

ArticleYear
The Italian Unitary Society of Colon-proctology (SIUCP: Società Italiana Unitaria di Colonproctologia) guidelines for the management of anal fissure.
    BMC surgery, 2023, Oct-13, Volume: 23, Issue:1

    Topics: Anal Canal; Chronic Disease; Colon; Colorectal Surgery; Fissure in Ano; Humans; Lidocaine; Treatment

2023
Coccydynia relieved by a tarsal tunnel block: a case series.
    Journal of medical case reports, 2019, Nov-21, Volume: 13, Issue:1

    Topics: Adult; Anesthetics, Local; Chronic Disease; Coccyx; Humans; Lidocaine; Low Back Pain; Male; Nerve Bl

2019
Sonography-guided trigger point injections in abdominal myofascial pain syndrome.
    Medicine, 2020, Dec-04, Volume: 99, Issue:49

    Topics: Abdominal Pain; Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Chronic Disease; Fem

2020
Ketamine for Refractory Chronic Migraine: An Observational Pilot Study and Metabolite Analysis.
    Journal of clinical pharmacology, 2021, Volume: 61, Issue:11

    Topics: Adult; Analgesics; Chronic Disease; Female; Humans; Ketamine; Lidocaine; Male; Middle Aged; Migraine

2021
Topical ketamine-amitriptyline-lidocaine for chronic pruritus: A retrospective study assessing efficacy and tolerability.
    Journal of the American Academy of Dermatology, 2017, Volume: 76, Issue:4

    Topics: Aged; Amines; Amitriptyline; Analgesics; Chronic Disease; Cyclohexanecarboxylic Acids; Drug Therapy,

2017
Basolateral amygdalar inactivation blocks chronic stress-induced lamina-specific reduction in prefrontal cortex volume and associated anxiety-like behavior.
    Progress in neuro-psychopharmacology & biological psychiatry, 2019, 01-10, Volume: 88

    Topics: Analysis of Variance; Anesthetics, Local; Animals; Anxiety; Avoidance Learning; Basolateral Nuclear

2019
Neurophysiological correlates of clinical improvement after greater occipital nerve (GON) block in chronic migraine: relevance for chronic migraine pathophysiology.
    The journal of headache and pain, 2018, Aug-20, Volume: 19, Issue:1

    Topics: Adolescent; Adult; Anesthetics, Local; Autonomic Nerve Block; Betamethasone; Chronic Disease; Evoked

2018
Lidocaine Potentiates SOCS3 to Attenuate Inflammation in Microglia and Suppress Neuropathic Pain.
    Cellular and molecular neurobiology, 2019, Volume: 39, Issue:8

    Topics: Animals; Calcium-Binding Proteins; Cell Line; Chronic Disease; Constriction, Pathologic; Cyclic AMP

2019
Treatment of refractory sclerodermatous chronic graft-versus-host disease with intravenous lidocaine infusions.
    Bone marrow transplantation, 2014, Volume: 49, Issue:2

    Topics: Administration, Intravenous; Adult; Aged; Anesthetics, Local; Chronic Disease; Female; Graft vs Host

2014
Rhinosinusitis associated with post-dental extraction chronic oroantral fistula: outcomes of non-surgical management comprising antibiotics and local decongestion therapy.
    The Journal of laryngology and otology, 2016, Volume: 130, Issue:6

    Topics: Administration, Topical; Adult; Aged; Anesthetics, Local; Anti-Bacterial Agents; Chronic Disease; Fe

2016
Preoperative β-blockade and hypertension in the first hour of functional endoscopic sinus surgery.
    The Laryngoscope, 2017, Volume: 127, Issue:7

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Anesthetics, Local; Chronic Disease; Dr

2017
Multimodal therapy for chronic tinnitus.
    The international tinnitus journal, 2008, Volume: 14, Issue:1

    Topics: Adult; Aged; Betahistine; Chronic Disease; Cinnarizine; Combined Modality Therapy; Dimenhydrinate; D

2008
A preliminary fMRI study of analgesic treatment in chronic back pain and knee osteoarthritis.
    Molecular pain, 2008, Oct-25, Volume: 4

    Topics: Adult; Aged; Analgesia; Back Pain; Brain Mapping; Chronic Disease; Female; Gyrus Cinguli; Humans; Li

2008
Persistent deep mechanical hyperalgesia induced by repeated cold stress in rats.
    European journal of pain (London, England), 2010, Volume: 14, Issue:3

    Topics: Analysis of Variance; Anesthetics, Local; Animals; Chronic Disease; Cold Temperature; Disease Models

2010
Preemptive analgesic effect of lidocaine in a chronic neuropathic pain model.
    Arquivos de neuro-psiquiatria, 2009, Volume: 67, Issue:4

    Topics: Anesthetics, Local; Animals; Chronic Disease; Disease Models, Animal; Lidocaine; Pain, Postoperative

2009
[Our experiences in chronic benign pain by injecting local anaesthetic into scars].
    La Clinica terapeutica, 2009, Volume: 160, Issue:6

    Topics: Adult; Aged; Anesthetics, Local; Chronic Disease; Cicatrix; Female; Humans; Injections, Intralesiona

2009
Treatment satisfaction in osteoarthritis and chronic low back pain: the role of pain, physical and emotional functioning, sleep, and adverse events.
    The journal of pain, 2011, Volume: 12, Issue:4

    Topics: Anesthetics, Local; Chronic Disease; Clinical Trials as Topic; Female; Humans; Lidocaine; Low Back P

2011
Pediatric sialendoscopy under local anesthesia: limitations and potentials.
    International journal of pediatric otorhinolaryngology, 2011, Volume: 75, Issue:2

    Topics: Adolescent; Ambulatory Care; Anesthesia, Local; Child; Chronic Disease; Cohort Studies; Endoscopy; F

2011
Transcriptional repression of the M channel subunit Kv7.2 in chronic nerve injury.
    Pain, 2011, Volume: 152, Issue:4

    Topics: Aminopyridines; Analgesics; Analysis of Variance; Anesthetics, Local; Animals; Chronic Disease; Dise

2011
Pharmacologic atrial defibrillation by drug delivery into the temporarily occluded coronary sinus. A canine study.
    International heart journal, 2012, Volume: 53, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Balloon Occlusion; Cardiac Pacing, Artificial;

2012
Successful treatment of intractable hiccups by oral application of lidocaine.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2012, Volume: 20, Issue:11

    Topics: Administration, Oral; Adult; Aged; Anesthetics, Local; Chronic Disease; Gels; Hiccup; Humans; Lidoca

2012
Reversible nasal airway obstruction: does change in nasal peak inspiratory flow following decongestion predict response to topical steroids in chronic rhinosinusitis patients?
    The Journal of laryngology and otology, 2012, Volume: 126, Issue:12

    Topics: Administration, Intranasal; Adult; Aged; Chronic Disease; Humans; Lidocaine; Middle Aged; Nasal Deco

2012
Long-term safety of nebulized lidocaine for adults with difficult-to-control chronic cough: a case series.
    Chest, 2013, Volume: 143, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Chronic Disease; Cough; Female; Humans; Intervie

2013
Lidocaine patch 5% and the management of chronic pain.
    Southern medical journal, 2002, Volume: 95, Issue:7

    Topics: Administration, Cutaneous; Anesthetics, Local; Chronic Disease; Humans; Lidocaine; Pain; Primary Hea

2002
Is topical nifedipine effective for chronic anal fissures?
    The Journal of family practice, 2003, Volume: 52, Issue:3

    Topics: Administration, Topical; Anesthetics, Local; Chronic Disease; Double-Blind Method; Evidence-Based Me

2003
Somato-sympathetic vasoconstriction to intranasal fluid administration with consecutive decrease in nasal nitric oxide.
    Acta physiologica Scandinavica, 2003, Volume: 177, Issue:4

    Topics: Acetylcysteine; Administration, Intranasal; Adult; Anesthetics, Local; Chronic Disease; Expectorants

2003
Shoulder impingement presenting as neck pain.
    The Journal of bone and joint surgery. American volume, 2003, Volume: 85, Issue:4

    Topics: Adolescent; Adult; Anesthetics, Local; Anti-Inflammatory Agents; Chronic Disease; Diagnosis, Differe

2003
Lidocaine patch helpful in managing the chronic pain of leg ulceration.
    Journal of the American Academy of Dermatology, 2003, Volume: 49, Issue:5

    Topics: Administration, Topical; Anesthetics, Local; Chronic Disease; Female; Humans; Leg Ulcer; Lidocaine;

2003
Plain talk about wound pain.
    Ostomy/wound management, 2003, Volume: 49, Issue:9

    Topics: Administration, Cutaneous; Algorithms; Anesthetics, Local; Chronic Disease; Decision Trees; Humans;

2003
Transient ischemic attack after electromotive drug administration for chronic non-infectious cystitis: report of two similar cases.
    Neurourology and urodynamics, 2004, Volume: 23, Issue:2

    Topics: Aged; Chronic Disease; Cystitis; Dexamethasone; Drug Delivery Systems; Electrophoresis; Epinephrine;

2004
Preliminary results of colour Doppler-guided intratendinous glucocorticoid injection for Achilles tendonitis in five patients.
    Scandinavian journal of medicine & science in sports, 2004, Volume: 14, Issue:2

    Topics: Achilles Tendon; Adult; Aged; Chronic Disease; Drug Combinations; Drug Therapy, Computer-Assisted; E

2004
Prevalence of facet joint pain in chronic spinal pain of cervical, thoracic, and lumbar regions.
    BMC musculoskeletal disorders, 2004, May-28, Volume: 5

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Back Pain; Bupivacaine; Cervical Vertebrae; Chro

2004
Introduction: chronic pain studies of the lidocaine patch 5% using the Neuropathic Pain Scale.
    Current medical research and opinion, 2004, Volume: 20 Suppl 2

    Topics: Administration, Cutaneous; Anesthetics, Local; Chronic Disease; Humans; Lidocaine; Neuralgia; Pain;

2004
Conclusions: chronic pain studies of lidocaine patch 5% using the Neuropathic Pain Scale.
    Current medical research and opinion, 2004, Volume: 20 Suppl 2

    Topics: Administration, Cutaneous; Anesthetics, Local; Chronic Disease; Clinical Trials as Topic; Humans; Li

2004
Transient tetraplegia after cervical facet joint injection for chronic neck pain administered without imaging guidance.
    Clinical neurology and neurosurgery, 2006, Volume: 108, Issue:7

    Topics: Adult; Anesthetics, Local; Arteries; Atropine; Bradycardia; Cervical Vertebrae; Chronic Disease; Dia

2006
Cervicogenic headache in patients with presumed migraine: missed diagnosis or misdiagnosis?
    The journal of pain, 2005, Volume: 6, Issue:10

    Topics: Adult; Aged; Anesthetics, Local; Bupivacaine; Cervical Plexus; Cervical Vertebrae; Chronic Disease;

2005
Pain management with interventional spine therapy in patients with spinal cord injury: a case series.
    The journal of spinal cord medicine, 2005, Volume: 28, Issue:4

    Topics: Adult; Anesthetics, Local; Anti-Inflammatory Agents; Autonomic Dysreflexia; Chronic Disease; Disease

2005
The lidocaine patch: a useful addition to the pain clinic armamentarium.
    Anaesthesia, 2006, Volume: 61, Issue:4

    Topics: Administration, Cutaneous; Adult; Anesthetics, Local; Chronic Disease; Female; Humans; Lidocaine; Ne

2006
Plain talk about wound pain.
    Ostomy/wound management, 2005, Volume: 51, Issue:11A Suppl

    Topics: Acute Disease; Anesthetics, Local; Attitude to Health; Chronic Disease; Humans; Lidocaine; Nursing A

2005
Retrobulbar alcohol injection for orbital pain relief under difficult circumstances: a case report.
    Annals of the Academy of Medicine, Singapore, 2006, Volume: 35, Issue:4

    Topics: Analgesia; Anti-Infective Agents, Local; Carcinoma, Adenoid Cystic; Chronic Disease; Ethanol; Humans

2006
Heterotopic inputs facilitate poststimulus afterdischarges of spinal WDR neurons in rats with chronic nerve constriction.
    Brain research, 2006, Jul-12, Volume: 1099, Issue:1

    Topics: Action Potentials; Anesthetics, Local; Animals; Behavior, Animal; Chronic Disease; Constriction; Dis

2006
[Painful defecation and chronic functional constipation in children: Diagnosis and treatment].
    Minerva pediatrica, 2006, Volume: 58, Issue:3

    Topics: Anal Canal; Anesthetics, Local; Child; Child, Preschool; Chronic Disease; Constipation; Defecation;

2006
Transient abducens nerve palsy during endoscopic sinus surgery: report of three cases.
    Auris, nasus, larynx, 2007, Volume: 34, Issue:2

    Topics: Abducens Nerve Diseases; Adolescent; Anesthesia, Local; Chronic Disease; Diplopia; Endoscopy; Humans

2007
[Effects of lidocaine on learning and memory dysfunction as well neuropathologic change induced by chronic stress: experiment with mice].
    Zhonghua yi xue za zhi, 2006, Dec-19, Volume: 86, Issue:47

    Topics: Anesthetics, Local; Animals; Chronic Disease; Hippocampus; Injections, Intraperitoneal; Lidocaine; M

2006
The duration of spinal anesthesia with 5% lidocaine in chronic opium abusers compared with nonabusers.
    Anesthesia and analgesia, 2007, Volume: 105, Issue:2

    Topics: Adult; Anesthesia, Spinal; Case-Control Studies; Chronic Disease; Elective Surgical Procedures; Fema

2007
[The effects of lidocaine and chronic stress on neurogenesis in the hippocampal dentate gyrus of adult mice].
    Zhonghua yi xue za zhi, 2007, May-22, Volume: 87, Issue:19

    Topics: Anesthetics, Local; Animals; Brain-Derived Neurotrophic Factor; Cell Proliferation; Chronic Disease;

2007
Multivariate analysis of chronic pain patients undergoing lidocaine infusions: increasing pain severity and advancing age predict likelihood of clinically meaningful analgesia.
    The Clinical journal of pain, 2007, Volume: 23, Issue:8

    Topics: Adolescent; Adult; Aged; Aging; Analysis of Variance; Anesthetics, Local; Chronic Disease; Cohort St

2007
Mexiletine therapy for chronic pain: survival analysis identifies factors predicting clinical success.
    Journal of pain and symptom management, 2008, Volume: 35, Issue:3

    Topics: Adolescent; Adult; Aged; Anesthetics, Local; Choice Behavior; Chronic Disease; Female; Humans; Kapla

2008
High-resolution ultrasound and magnetic resonance imaging to document tissue repair after prolotherapy: a report of 3 cases.
    Archives of physical medicine and rehabilitation, 2008, Volume: 89, Issue:2

    Topics: Adolescent; Adult; Anesthetics, Local; Ankle Injuries; Athletic Injuries; Chronic Disease; Female; G

2008
Experimental autoimmune prostatitis induces chronic pelvic pain.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2008, Volume: 294, Issue:4

    Topics: Amines; Analgesics; Anesthetics, Local; Animals; Autoimmune Diseases; Chronic Disease; Cyclohexaneca

2008
Lidocaine 5% patch for localized chronic neuropathic pain in adolescents: report of five cases.
    Paediatric anaesthesia, 2008, Volume: 18, Issue:6

    Topics: Administration, Cutaneous; Adolescent; Anesthetics, Local; Child; Chronic Disease; Cicatrix; Female;

2008
C-fiber spontaneous discharge evoked by chronic inflammation is suppressed by a long-term infusion of lidocaine yielding nanogram per milliliter plasma levels.
    Pain, 2008, Volume: 137, Issue:1

    Topics: Animals; Chronic Disease; Hyperalgesia; Inflammation; Infusion Pumps; Lidocaine; Male; Nanostructure

2008
Effects of intrathecal lidocaine on hyperalgesia and allodynia following chronic constriction injury in rats.
    European journal of pain (London, England), 2009, Volume: 13, Issue:2

    Topics: Anesthetics, Local; Animals; Behavior, Animal; Chronic Disease; Constriction, Pathologic; Hot Temper

2009
Antimicrobials in periodontics: controlling chronic disease.
    Dentistry today, 2008, Volume: 27, Issue:4

    Topics: Anesthetics, Combined; Anesthetics, Local; Anti-Bacterial Agents; Bacteroidaceae Infections; Bactero

2008
Adiposis dolorosa as an etiology of abdominal pain.
    Wiener klinische Wochenschrift, 2008, Volume: 120, Issue:7-8

    Topics: Abdominal Pain; Abdominal Wall; Adiposis Dolorosa; Anesthetics, Local; Chronic Disease; Diagnosis, D

2008
Surgical control of chronic migrainous neuralgia by trigeminal ganglio-rhizolysis.
    Journal of neurosurgery, 1982, Volume: 57, Issue:4

    Topics: Adult; Chronic Disease; Ergotamine; Humans; Lidocaine; Lithium; Male; Methysergide; Middle Aged; Mig

1982
Low back pain.
    Hospital practice (Office ed.), 1982, Volume: 17, Issue:11

    Topics: Adult; Back Pain; Chronic Disease; Electric Stimulation Therapy; Exercise Therapy; Female; Hot Tempe

1982
[Diagnostic celiac block. Alternative to surgery in chronic pancreatitis].
    Presse medicale (Paris, France : 1983), 1984, Jun-02, Volume: 13, Issue:23

    Topics: Autonomic Nerve Block; Celiac Plexus; Chronic Disease; Humans; Lidocaine; Male; Pancreatitis

1984
Persistent abdominal pain. Treatment by lumbar sympathetic lysis.
    Anaesthesia, 1981, Volume: 36, Issue:3

    Topics: Abdomen; Adult; Chronic Disease; Female; Humans; Lidocaine; Lumbosacral Region; Male; Middle Aged; N

1981
Chronic sprains of the carpometacarpal joints.
    The Journal of hand surgery, 1981, Volume: 6, Issue:2

    Topics: Adolescent; Adult; Aged; Arthrodesis; Chronic Disease; Female; Follow-Up Studies; Humans; Lidocaine;

1981
Effects of smoking and chronic hepatitis B on lidocaine and indocyanine green kinetics.
    Clinical pharmacology and therapeutics, 1980, Volume: 28, Issue:2

    Topics: Administration, Oral; Adult; Biological Availability; Chronic Disease; Female; Hepatitis B; Humans;

1980
Facilitation of reentry by lidocaine in canine myocardial infarction.
    Acta physiologica Hungarica, 1994, Volume: 82, Issue:3

    Topics: Acute Disease; Animals; Chronic Disease; Dogs; Electrocardiography; Electrophysiology; Heart Conduct

1994
[The lidocaine test in tinnitus. Determination of its current status].
    HNO, 1994, Volume: 42, Issue:11

    Topics: Administration, Oral; Adult; Aged; Auditory Threshold; Chronic Disease; Diazepam; Dose-Response Rela

1994
Lignocaine and headache: an electrophysiological study in the cat with supporting clinical observations in man.
    Journal of neurology, 1994, Volume: 241, Issue:7

    Topics: Animals; Cats; Chronic Disease; Dose-Response Relationship, Drug; Electric Stimulation; Evoked Poten

1994
Hepatic lidocaine metabolism and liver histology in patients with chronic hepatitis and cirrhosis.
    Hepatology (Baltimore, Md.), 1994, Volume: 19, Issue:4

    Topics: Adult; Aged; Alanine Transaminase; Chronic Disease; Female; Hepatitis; Humans; Lidocaine; Liver; Liv

1994
Nebulized lidocaine in the treatment of refractory cough.
    Chest, 1994, Volume: 105, Issue:5

    Topics: Aerosols; Chronic Disease; Cough; Humans; Lidocaine; Male; Middle Aged

1994
CT-guided injection of the stellate ganglion: description of technique and efficacy of sympathetic blockade.
    Radiology, 1993, Volume: 188, Issue:3

    Topics: Adult; Autonomic Nerve Block; Bupivacaine; Buprenorphine; Chronic Disease; Female; Humans; Injection

1993
The skinache syndrome.
    Journal of the Royal Society of Medicine, 1995, Volume: 88, Issue:10

    Topics: Aged; Anesthetics, Local; Chronic Disease; Female; Humans; Lidocaine; Male; Middle Aged; Pain Manage

1995
Percutaneous pancreatography under ultrasonographic guidance.
    Acta radiologica (Stockholm, Sweden : 1987), 1996, Volume: 37, Issue:1

    Topics: Anesthesia, Local; Chronic Disease; Diagnosis, Differential; Fluoroscopy; Humans; Lidocaine; Pancrea

1996
Cases 1A and 1B. 1995 intravenous lidocaine infusion for chronic pain therapy.
    Israel journal of medical sciences, 1996, Volume: 32, Issue:5

    Topics: Adult; Anesthetics, Local; Causalgia; Chronic Disease; Drug Monitoring; Herpes Zoster; Humans; Infus

1996
Regional anesthesia in knee arthroscopy: a new technique involving femoral and sciatic nerve blocks in knee arthroscopy.
    Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 1996, Volume: 12, Issue:1

    Topics: Adult; Anesthesia, Conduction; Anesthetics, Local; Anterior Cruciate Ligament; Anterior Cruciate Lig

1996
Cortical facilitatory action on centralis lateralis thalamic activity during the development of carrageenin-produced inflammation.
    Archives of medical research, 1996,Autumn, Volume: 27, Issue:3

    Topics: Acute Disease; Afferent Pathways; Anesthetics, Local; Animals; Carrageenan; Chronic Disease; Edema;

1996
Prognostic value of the monoethylglycinexylidide test in pediatric liver transplant candidates.
    Therapeutic drug monitoring, 1996, Volume: 18, Issue:4

    Topics: Adolescent; Child; Child, Preschool; Chronic Disease; Female; Humans; Infant; Lidocaine; Liver Failu

1996
Use of hepatic lidocaine metabolism to monitor patients with chronic liver disease.
    Therapeutic drug monitoring, 1996, Volume: 18, Issue:4

    Topics: Anesthetics, Local; Chronic Disease; Genetic Variation; Humans; Infusions, Intravenous; Lidocaine; L

1996
Sphenopalatine ganglion block: a safe and easy method for the management of orofacial pain.
    Cranio : the journal of craniomandibular practice, 1995, Volume: 13, Issue:3

    Topics: Acute Disease; Administration, Intranasal; Anesthetics, Local; Autonomic Nerve Block; Chronic Diseas

1995
Management of chronic pain with epidural steroids.
    AORN journal, 1997, Volume: 65, Issue:4

    Topics: Anesthetics, Local; Anti-Inflammatory Agents; Chronic Disease; Drug Combinations; Female; Humans; In

1997
Prolotherapy for chronic headache.
    Headache, 1997, Volume: 37, Issue:4

    Topics: Chronic Disease; Follow-Up Studies; Glucose; Headache; Humans; Injections; Lidocaine

1997
Assessment of monoethylglycinexylidide as measure of liver function for patients with chronic viral hepatitis.
    Clinical chemistry, 1997, Volume: 43, Issue:10

    Topics: Adult; Biopsy; Chronic Disease; Female; Hepatitis, Viral, Human; Humans; Lidocaine; Liver; Liver Fun

1997
Intravesical electromotive drug administration for the treatment of non-infectious chronic cystitis.
    International urogynecology journal and pelvic floor dysfunction, 1997, Volume: 8, Issue:3

    Topics: Administration, Intravesical; Adult; Aged; Anesthetics, Local; Anti-Inflammatory Agents; Chronic Dis

1997
[Chronic tinnitus in children and adolescents].
    HNO, 1997, Volume: 45, Issue:11

    Topics: Adolescent; Age Factors; Audiometry, Pure-Tone; Audiometry, Speech; Child; Chronic Disease; Counseli

1997
The cold plate as a test of nociceptive behaviors: description and application to the study of chronic neuropathic and inflammatory pain models.
    Pain, 1998, Volume: 75, Issue:2-3

    Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Behavior, Animal; Chronic Disease; Clonidine; Cold

1998
Progressive liver functional impairment is associated with an increase in AST/ALT ratio.
    Digestive diseases and sciences, 1999, Volume: 44, Issue:6

    Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Chronic Disease; Clinical Enzyme Tests; Di

1999
[Monoethylglycinexylidide--a metabolite of lidocaine--as an index of liver function in chronic hepatic parenchymal diseases].
    Bratislavske lekarske listy, 1999, Volume: 100, Issue:1

    Topics: Adult; Aged; Chronic Disease; Female; Fluorescence Polarization Immunoassay; Humans; Lidocaine; Live

1999
Customized EMG needle insertion guide for the muscle afferent block of jaw-deviation and jaw-opening dystonias.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 1999, Volume: 88, Issue:6

    Topics: Adult; Afferent Pathways; Aged; Anesthetics, Local; Chronic Disease; Dystonic Disorders; Electrodes;

1999
Chronic urticaria serum induces histamine release, leukotriene production, and basophil CD63 surface expression--inhibitory effects ofanti-inflammatory drugs.
    The Journal of allergy and clinical immunology, 2000, Volume: 105, Issue:3

    Topics: Anti-Inflammatory Agents; Antigens, CD; Antigens, Surface; Basophils; Chloroquine; Chronic Disease;

2000
Intravenous lignocaine infusions for severe chronic daily headache.
    The Medical journal of Australia, 2000, Feb-21, Volume: 172, Issue:4

    Topics: Adolescent; Adult; Anesthetics, Local; Chronic Disease; Clinical Protocols; Drug Monitoring; Female;

2000
Open lateral sphincterotomy is still the best treatment for chronic anal fissure.
    American journal of surgery, 2000, Volume: 179, Issue:3

    Topics: Ambulatory Surgical Procedures; Anal Canal; Anesthetics, Local; Bupivacaine; Chronic Disease; Fissur

2000
Therapeutic zygapophyseal joint injections for headaches emanating from the C2-3 joint.
    American journal of physical medicine & rehabilitation, 2001, Volume: 80, Issue:3

    Topics: Adult; Anesthetics, Local; Anti-Inflammatory Agents; Betamethasone; Cervical Vertebrae; Chronic Dise

2001
Beneficial effect of intravenous lidocaine in cutaneous chronic graft-versus-host disease secondary to donor lymphocyte infusion.
    Bone marrow transplantation, 2001, Volume: 28, Issue:1

    Topics: Adult; Bone Marrow Transplantation; Child; Chronic Disease; Female; Graft vs Host Disease; Humans; I

2001
[Expanding the view].
    HNO, 2001, Volume: 49, Issue:10

    Topics: Chronic Disease; Clinical Trials as Topic; Combined Modality Therapy; Counseling; Hemodilution; Huma

2001
Electropharmacologic effects of pilsicainide, a pure sodium channel blocker, on the remodeled atrium subjected to chronic rapid pacing.
    Journal of cardiovascular pharmacology, 2001, Volume: 38, Issue:6

    Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Function; Cardiac Pacing, Artificial; C

2001
Practice tips. Treating persistent cough. Try a nebulized mixture of lidocaine and bupivacaine.
    Canadian family physician Medecin de famille canadien, 2002, Volume: 48

    Topics: Administration, Inhalation; Anesthetics, Local; Bupivacaine; Chronic Disease; Cough; Humans; Lidocai

2002
Continual systemic infusion of lidocaine provides analgesia in an animal model of neuropathic pain.
    Pain, 2002, Volume: 97, Issue:3

    Topics: Anesthetics, Local; Animals; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Dr

2002
Treating persistent cough: caution!
    Canadian family physician Medecin de famille canadien, 2002, Volume: 48

    Topics: Anesthetics, Local; Bronchoconstriction; Chronic Disease; Cough; Humans; Lidocaine

2002
[Treatment directives for patients with intervertebral-disk diseases of the lumbar spine].
    Medizinische Monatsschrift, 1977, Volume: 31, Issue:11

    Topics: Adult; Aged; Back Pain; Chronic Disease; Humans; Intervertebral Disc Displacement; Lidocaine; Lumbar

1977
[Clinical and immunological results after chemical synovectomy].
    Orvosi hetilap, 1979, May-27, Volume: 120, Issue:21

    Topics: Adolescent; Adult; Aged; Arthritis; Chronic Disease; Female; Humans; Hydrocortisone; Immunoglobulins

1979
Arrhythmias in chronic pulmonary disease.
    Angiology, 1979, Volume: 30, Issue:10

    Topics: Arrhythmias, Cardiac; Chronic Disease; Digoxin; Humans; Hypokalemia; Hypoxia; Lidocaine; Lung Diseas

1979
Vertical pendular nystagmus in chronic myositis of medial and lateral rectus.
    Annals of ophthalmology, 1978, Volume: 10, Issue:12

    Topics: Adult; Chronic Disease; Diplopia; Drug Hypersensitivity; Female; Humans; Lidocaine; Mepivacaine; Myo

1978
Antipyrine, paracetamol, and lignocaine elimination in chronic liver disease.
    British medical journal, 1977, May-28, Volume: 1, Issue:6073

    Topics: Acetaminophen; Adult; Aged; Antipyrine; Chronic Disease; Female; Half-Life; Humans; Kinetics; Lidoca

1977
Effect of fiberoptic bronchoscopy on respiratory performance in patients with chronic airways obstruction.
    Thorax, 1975, Volume: 30, Issue:4

    Topics: Adult; Aged; Airway Obstruction; Airway Resistance; Bronchoscopy; Carbon Dioxide; Chronic Disease; F

1975
Proceedings: Antipyrine, lingocaine and paracetamol metabolism in chronic liver disease.
    Gut, 1975, Volume: 16, Issue:10

    Topics: Acetaminophen; Adult; Aged; Antipyrine; Chronic Disease; Female; Humans; Lidocaine; Liver Diseases;

1975
[Does the differential block by the epidural route provide a diagnostic aid in chronic pain?].
    Cahiers d'anesthesiologie, 1992, Volume: 40, Issue:8

    Topics: Aged; Analgesia, Epidural; Autonomic Nerve Block; Chronic Disease; Female; Humans; Lidocaine; Male;

1992
Chronic interstitial cystitis. Successful treatment with intravesical idocaine.
    Archivio italiano di urologia, nefrologia, andrologia : organo ufficiale dell'Associazione per la ricerca in urologia = Urological, nephrological, and andrological sciences, 1992, Volume: 64, Issue:4

    Topics: Administration, Intravesical; Chronic Disease; Cystitis; Female; Humans; Lidocaine; Middle Aged

1992
Predictive performance of Bayesian and nonlinear least-squares regression programs for lidocaine.
    Therapeutic drug monitoring, 1992, Volume: 14, Issue:4

    Topics: Acute Disease; Arrhythmias, Cardiac; Bayes Theorem; Chronic Disease; Humans; Least-Squares Analysis;

1992
Comparative pharmacodynamics of intravenous lidocaine in patients with acute and chronic ventricular arrhythmias.
    The Annals of pharmacotherapy, 1992, Volume: 26, Issue:6

    Topics: Acute Disease; Aged; Arrhythmias, Cardiac; Chronic Disease; Female; Heart Ventricles; Humans; Infusi

1992
Chronic abdominal pain due to periostitis pubis. A new syndrome.
    Postgraduate medicine, 1992, Volume: 91, Issue:1

    Topics: Abdominal Pain; Adult; Chronic Disease; Humans; Injections; Lidocaine; Male; Periostitis; Prednisolo

1992
The management of oral mexiletine and intravenous lidocaine to treat chronic painful symmetrical distal diabetic neuropathy.
    The Journal of the Kentucky Medical Association, 1991, Volume: 89, Issue:10

    Topics: Chronic Disease; Diabetic Neuropathies; Drug Therapy, Combination; Female; Humans; Infusions, Intrav

1991
Sphenopalatine block--the cheapest technique in the management of chronic pain.
    The Clinical journal of pain, 1991, Volume: 7, Issue:3

    Topics: Aerosols; Chronic Disease; Humans; Lidocaine; Nerve Block; Pain; Pain Management

1991
Studies in autotomy: its pathophysiology and usefulness as a model of chronic pain.
    Pain, 1991, Volume: 45, Issue:2

    Topics: Afferent Pathways; Animals; Behavior, Animal; Chronic Disease; Denervation; Disease Models, Animal;

1991
Lidocaine-induced spinal block can relieve central poststroke pain: role of the block in chronic pain diagnosis.
    Anesthesiology, 1991, Volume: 74, Issue:1

    Topics: Aged; Anesthesia, Spinal; Brain; Cerebrovascular Disorders; Chronic Disease; Humans; Lidocaine; Male

1991
Treatment of benign chronic abdominal pain with neurolytic celiac plexus block.
    Anesthesiology, 1991, Volume: 75, Issue:1

    Topics: Abdominal Pain; Adult; Bupivacaine; Celiac Plexus; Chronic Disease; Female; Humans; Lidocaine; Nerve

1991
Unusual complications of the treatment of chronic spinal arachnoiditis.
    The Clinical journal of pain, 1990, Volume: 6, Issue:3

    Topics: Aged; Analgesia, Epidural; Arachnoiditis; Chronic Disease; Clonidine; Female; Humans; Injections; Li

1990
Chronic cervical spinal cord injury and autonomic hyperreflexia in rats.
    The American journal of physiology, 1990, Volume: 258, Issue:1 Pt 2

    Topics: Animals; Autonomic Nervous System; Blood Pressure; Chronic Disease; Decerebrate State; Injections; L

1990
Assessment of lidocaine metabolite formation as a quantitative liver function test in children.
    Hepatology (Baltimore, Md.), 1990, Volume: 12, Issue:3 Pt 1

    Topics: Adolescent; Bilirubin; Child; Child, Preschool; Chronic Disease; Fluoroimmunoassay; Humans; Infant;

1990
Diagnostic epidural opioid technique.
    The Clinical journal of pain, 1989, Volume: 5, Issue:3

    Topics: Adult; Age Factors; Aged; Analgesia, Epidural; Chronic Disease; Disability Evaluation; Female; Fenta

1989
[The combined treatment with aurobin and dipromonium of focal scleroderma].
    Vestnik dermatologii i venerologii, 1989, Issue:9

    Topics: Adult; Chronic Disease; Dermatologic Agents; Drug Combinations; Drug Evaluation; Drug Therapy, Combi

1989
Diagnostic epidural opioid blockade and chronic pain: preliminary report.
    Pain, 1985, Volume: 21, Issue:2

    Topics: Adult; Aged; Anesthesia, Epidural; Back Pain; Chronic Disease; Diagnosis, Differential; Female; Fent

1985
Local injection therapy for the treatment of chronic pain.
    The Practitioner, 1988, Jun-08, Volume: 232, Issue:1450

    Topics: Adolescent; Adult; Aged; Chronic Disease; Female; Humans; Injections; Lidocaine; Male; Middle Aged;

1988
Differential effects of procainamide, lidocaine and acetylstrophanthidin on body surface potentials and epicardial conduction in dogs with chronic myocardial infarction.
    Journal of the American College of Cardiology, 1988, Volume: 11, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chronic Disease; Dogs; Electrocardiography; E

1988
Post-traumatic arthrosis of the index carpometacarpal joint. A rationale for treatment and report of two cases.
    Orthopedics, 1987, Volume: 10, Issue:10

    Topics: Adult; Arthrodesis; Chronic Disease; Female; Humans; Lidocaine; Male; Metacarpus; Methylprednisolone

1987
[The use of lidocaine inhalation in chronic bronchitis].
    Pneumonologia polska, 1986, Volume: 54, Issue:4

    Topics: Adult; Bronchitis; Chronic Disease; Female; Humans; Lidocaine; Male; Middle Aged; Respiratory Therap

1986
[Effects of intravenous infusion of xylocaine on the extrasystole of chronic Chagasic cardiopathy].
    Revista paulista de medicina, 1972, Volume: 80, Issue:3

    Topics: Adult; Cardiac Complexes, Premature; Chagas Disease; Chronic Disease; Drug Evaluation; Female; Human

1972
Management of chronic and recurrent gout.
    Modern treatment, 1971, Volume: 8, Issue:4

    Topics: Adrenocorticotropic Hormone; Allopurinol; Chronic Disease; Colchicine; Dexamethasone; Diet Therapy;

1971
Comparison of the effect of propranolol, lignocaine, and other drugs on normal and raised intraocular pressure in man.
    American journal of ophthalmology, 1971, Volume: 72, Issue:4

    Topics: Acute Disease; Adrenergic beta-Antagonists; Adult; Aged; Analysis of Variance; Anesthetics, Local; C

1971
Gross impairment of hepatic drug metabolism in a patient with chronic liver disease.
    British medical journal, 1974, Nov-16, Volume: 4, Issue:5941

    Topics: Adult; Antipyrine; Biotransformation; Chronic Disease; Female; Half-Life; Hepatitis; Humans; Jaundic

1974
Proceedings: Pancreatic changes induced by chronic (two years) ethanol treatment in the dog.
    Gut, 1974, Volume: 15, Issue:10

    Topics: Animals; Atropine; Bicarbonates; Chronic Disease; Dogs; Dose-Response Relationship, Drug; Ethanol; G

1974
Local anaesthesia--a review of practice.
    Australian dental journal, 1974, Volume: 19, Issue:5

    Topics: Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Antidepressive Agents; Chronic Disease; D

1974
The effect of environmental temperature on airway resistance in the asthmatic child.
    Pediatric research, 1973, Volume: 7, Issue:7

    Topics: Adolescent; Airway Resistance; Anesthesia, Local; Asthma; Bronchi; Child; Chronic Disease; Cold Temp

1973
His bundle electrograms.
    The Medical journal of Australia, 1973, Aug-11, Volume: 2, Issue:1

    Topics: Aged; Arrhythmias, Cardiac; Bundle-Branch Block; Cardiac Catheterization; Chronic Disease; Electroca

1973
[Therapeutic results of osmic acid synovio-orthesis].
    Schweizerische medizinische Wochenschrift, 1974, May-11, Volume: 104, Issue:19

    Topics: Chronic Disease; Follow-Up Studies; Humans; Injections, Intra-Articular; Lidocaine; Methods; Osmium;

1974
[Comparison of 2 modern antiarrhythmic drugs: lidocaine and diphenylhydantoin].
    Giornale italiano di cardiologia, 1972, Volume: 2, Issue:4

    Topics: Arrhythmias, Cardiac; Brain; Chronic Disease; Hemodynamics; Humans; Hypotension; Lidocaine; Necrosis

1972
Lidocaine in obstructive pulmonary disease.
    JAMA, 1972, Jun-12, Volume: 220, Issue:11

    Topics: Acute Disease; Chronic Disease; Humans; Injections, Intravenous; Lidocaine; Lung Diseases, Obstructi

1972
A step towards the more rational treatment of chronic pain by nerve block. Case report.
    British journal of anaesthesia, 1972, Volume: 44, Issue:8

    Topics: Abdomen; Adult; Autonomic Nerve Block; Chronic Disease; Humans; Lidocaine; Male; Methods; Pain Manag

1972
Lumbar epidural injection for the treatment of chronic sciatica.
    Rheumatology and physical medicine, 1970, Volume: 10, Issue:7

    Topics: Adult; Age Factors; Anesthesia, Spinal; Chronic Disease; Female; Follow-Up Studies; Humans; Hydrocor

1970
[Bronchoscopic sanitation in the treatment of chronic pneumonia with an asthmatic component].
    Vestnik khirurgii imeni I. I. Grekova, 1971, Volume: 106, Issue:1

    Topics: Asthma; Bronchoscopy; Child; Chronic Disease; Drainage; Humans; Lidocaine; Pneumonia; Povidone; Ther

1971