lidocaine has been researched along with Choriocarcinoma in 1 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Choriocarcinoma: A malignant metastatic form of trophoblastic tumors. Unlike the HYDATIDIFORM MOLE, choriocarcinoma contains no CHORIONIC VILLI but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (TROPHOBLASTS). It is characterized by the large amounts of CHORIONIC GONADOTROPIN produced. Tissue origins can be determined by DNA analyses: placental (fetal) origin or non-placental origin (CHORIOCARCINOMA, NON-GESTATIONAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lidocaine treatment reduced the ABCG2, P-gp, MRP1, and MRP2 protein levels in cells." | 5.51 | Lidocine potentiates the cytotoxicity of 5-fluorouracil to choriocarcinoma cells by downregulating ABC transport proteins expression. ( Liu, H; Pang, W; Wang, J; Zhang, X, 2019) |
| "Lidocaine treatment reduced the ABCG2, P-gp, MRP1, and MRP2 protein levels in cells." | 1.51 | Lidocine potentiates the cytotoxicity of 5-fluorouracil to choriocarcinoma cells by downregulating ABC transport proteins expression. ( Liu, H; Pang, W; Wang, J; Zhang, X, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, X | 1 |
| Pang, W | 1 |
| Liu, H | 1 |
| Wang, J | 1 |
1 other study available for lidocaine and Choriocarcinoma
| Article | Year |
|---|---|
Lidocine potentiates the cytotoxicity of 5-fluorouracil to choriocarcinoma cells by downregulating ABC transport proteins expression.
Topics: ATP-Binding Cassette Transporters; Cell Line, Tumor; Choriocarcinoma; Cytotoxins; Down-Regulation; F | 2019 |