lidocaine has been researched along with Cholera Infantum in 19 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This systematic review evaluates the safety and efficacy of intravenous (IV) lidocaine for the treatment of acute pain in adult patients." | 8.98 | Intravenous Lidocaine for Acute Pain: A Systematic Review. ( Barbas, B; Liang, E; Long, C; Masic, D; Rech, MA; Sterk, EJ, 2018) |
| "This systematic review evaluates the safety and efficacy of intravenous (IV) lidocaine for the treatment of acute pain in adult patients." | 4.98 | Intravenous Lidocaine for Acute Pain: A Systematic Review. ( Barbas, B; Liang, E; Long, C; Masic, D; Rech, MA; Sterk, EJ, 2018) |
| "Lidocaine lollipop is a promising form of local oropharyngeal anesthesia for EGD." | 2.73 | Lidocaine lollipop as single-agent anesthesia in upper GI endoscopy. ( Abdul-Baki, H; Ayoub, C; Nasr, V; Skoury, A; Soweid, A, 2007) |
| " Mean +/- SD volume of distribution at steady state, total body clearance, and terminal half-life were 0." | 2.72 | Influence of gastrointestinal tract disease on pharmacokinetics of lidocaine after intravenous infusion in anesthetized horses. ( Enns, RM; Feary, DJ; Mama, KR; Thomasy, SM; Wagner, AE, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (47.37) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 4 (21.05) | 29.6817 |
| 2010's | 5 (26.32) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Masic, D | 1 |
| Liang, E | 1 |
| Long, C | 1 |
| Sterk, EJ | 1 |
| Barbas, B | 1 |
| Rech, MA | 1 |
| Tran, BW | 1 |
| Dhillon, SK | 1 |
| Sun, JJ | 1 |
| Chu, ZJ | 1 |
| Liu, WF | 1 |
| Qi, SF | 1 |
| Yang, YH | 1 |
| Ge, PL | 1 |
| Zhang, XH | 1 |
| Li, WS | 1 |
| Yang, C | 1 |
| Zhang, YM | 1 |
| Heuss, LT | 1 |
| Hanhart, A | 1 |
| Dell-Kuster, S | 1 |
| Zdrnja, K | 1 |
| Ortmann, M | 1 |
| Beglinger, C | 1 |
| Bucher, HC | 1 |
| Degen, L | 1 |
| Berger, A | 1 |
| Sadosky, A | 1 |
| Dukes, E | 1 |
| Edelsberg, J | 1 |
| Oster, G | 1 |
| Feary, DJ | 1 |
| Mama, KR | 1 |
| Thomasy, SM | 1 |
| Wagner, AE | 1 |
| Enns, RM | 1 |
| Ayoub, C | 1 |
| Skoury, A | 1 |
| Abdul-Baki, H | 1 |
| Nasr, V | 1 |
| Soweid, A | 1 |
| Cook, VL | 1 |
| Blikslager, AT | 1 |
| Gerzilov, P | 1 |
| Viiazki, I | 1 |
| Iarŭmov, N | 1 |
| Mitov, A | 1 |
| Deredzhian, Kh | 1 |
| Ivanov, A | 1 |
| Korukov, B | 1 |
| D'Olimpio, J | 1 |
| Schwartz, GR | 1 |
| Stone, JH | 1 |
| Czinn, SJ | 1 |
| Carr, HS | 1 |
| Speck, WT | 1 |
| Gurevich, RA | 1 |
| Tsimmerman, IaS | 1 |
| Minkovich, LL | 1 |
| Krylov, AA | 1 |
| Chandler, F | 1 |
| Breithardt, G | 1 |
| Loogen, F | 1 |
| Seipel, L | 1 |
| Bleifeld, W | 1 |
| Merx, W | 1 |
| Effert, S | 1 |
| Ewy, GA | 1 |
| Marcus, FI | 1 |
| Fillmore, SJ | 1 |
| Matthews, NP | 1 |
| Leduc, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Intranasal Lidocaine for Prevention of Postoperative Nausea and Vomiting. A Prospective Double Blind Randomized Controlled Study.[NCT04810494] | Phase 4 | 0 participants (Actual) | Interventional | 2022-10-01 | Withdrawn (stopped due to Change in study team) | ||
| A Prospective, Randomized, Active-Comparator, Open-Label, Non-Inferiority Study of the Efficacy of Continuous Nerve Block vs Single Block Plus Intravenous Lidocaine for Postoperative Pain.[NCT04208516] | Phase 4 | 17 participants (Actual) | Interventional | 2021-05-26 | Terminated (stopped due to Recruitment was unable to be obtained in a timely fashion, so the study was stopped.) | ||
| Effect of Palatable Lidocaine Gel Versus Dexmedetomidine on Gag Reflex During Propofol Based Sedation for Patients Undergoing Elective Upper Gastrointestinal Endoscopy. A Randomized Controlled Study[NCT04213833] | 120 participants (Actual) | Interventional | 2020-01-01 | Completed | |||
| Study of Propofol Sedation During Upper Endoscopy With and Without Topical Pharyngeal Anesthesia[NCT01081002] | Phase 4 | 294 participants (Actual) | Interventional | 2009-08-31 | Completed | ||
| The Application of Topical Pharyngeal Anesthesia in the Esophagogastroduodenoscopy Under Sedation[NCT03070379] | 300 participants (Anticipated) | Interventional | 2017-02-20 | Recruiting | |||
| Cognitive Changes Associated With Initiation of Gabapentin Treatment in Adults With Chronic Pain[NCT04106011] | 3 participants (Actual) | Observational | 2020-01-10 | Terminated (stopped due to PI request - low enrollment) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Nausea and vomiting requiring treatment, hypotension, or bradycardia or tachycardia (NCT04208516)
Timeframe: From time of surgery to discharge, on average 1-4 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Continuous Nerve Blocks | 0 |
| Single Nerve Blocks Plus IV Lidocaine Infusion | 0 |
Local anesthetic consumption after surgery is reported in mg of lidocaine (NCT04208516)
Timeframe: 12 hours after surgery
| Intervention | mg (Mean) |
|---|---|
| Continuous Nerve Blocks | 574.29 |
| Single Nerve Blocks Plus IV Lidocaine Infusion | 600 |
Local anesthetic consumption after surgery is reported in mg of lidocaine (NCT04208516)
Timeframe: 24 hours after surgery
| Intervention | mg (Mean) |
|---|---|
| Continuous Nerve Blocks | 1096.07 |
| Single Nerve Blocks Plus IV Lidocaine Infusion | 1139.29 |
Local anesthetic consumption after surgery is reported in mg of lidocaine (NCT04208516)
Timeframe: 48 hours after surgery
| Intervention | mg (Mean) |
|---|---|
| Continuous Nerve Blocks | 1973.57 |
| Single Nerve Blocks Plus IV Lidocaine Infusion | 2308.33 |
Local anesthetic consumption after surgery is reported in mg of lidocaine (NCT04208516)
Timeframe: 72 hours after surgery
| Intervention | mg (Mean) |
|---|---|
| Continuous Nerve Blocks | 2721.79 |
| Single Nerve Blocks Plus IV Lidocaine Infusion | 2570.0 |
Opioids will be converted to oral morphine equivalents (NCT04208516)
Timeframe: 24 hours after surgery
| Intervention | OME (Mean) |
|---|---|
| Continuous Nerve Blocks | 34.93 |
| Single Nerve Blocks Plus IV Lidocaine Infusion | 46.50 |
Opioids will be converted to oral morphine equivalents (NCT04208516)
Timeframe: 48 hours after surgery
| Intervention | OME (Mean) |
|---|---|
| Continuous Nerve Blocks | 61.5 |
| Single Nerve Blocks Plus IV Lidocaine Infusion | 84.75 |
Opioids will be converted to oral morphine equivalents (NCT04208516)
Timeframe: 72 hours after surgery
| Intervention | OME (Mean) |
|---|---|
| Continuous Nerve Blocks | 88.57 |
| Single Nerve Blocks Plus IV Lidocaine Infusion | 128.1 |
By numeric pain rating scale, 0 = no pain and 10 = worst possible pain (NCT04208516)
Timeframe: 12 hours after surgery
| Intervention | score on a scale (Mean) |
|---|---|
| Continuous Nerve Blocks | 6.17 |
| Single Nerve Blocks Plus IV Lidocaine Infusion | 6.07 |
By numeric pain rating scale, 0 = no pain and 10 = worst possible pain (NCT04208516)
Timeframe: 24 hours after surgery
| Intervention | score on a scale (Mean) |
|---|---|
| Continuous Nerve Blocks | 4.5 |
| Single Nerve Blocks Plus IV Lidocaine Infusion | 6.43 |
By numeric pain rating scale, 0 = no pain and 10 = worst possible pain (NCT04208516)
Timeframe: 48 hours after surgery
| Intervention | score on a scale (Mean) |
|---|---|
| Continuous Nerve Blocks | 5.86 |
| Single Nerve Blocks Plus IV Lidocaine Infusion | 4.83 |
By numeric pain rating scale, 0 = no pain and 10 = worst possible pain (NCT04208516)
Timeframe: 6 hours after surgery
| Intervention | score on a scale (Mean) |
|---|---|
| Continuous Nerve Blocks | 6.17 |
| Single Nerve Blocks Plus IV Lidocaine Infusion | 6.14 |
By numeric pain rating scale, 0 = no pain and 10 = worst possible pain (NCT04208516)
Timeframe: 72 hours after surgery
| Intervention | score on a scale (Mean) |
|---|---|
| Continuous Nerve Blocks | 5.36 |
| Single Nerve Blocks Plus IV Lidocaine Infusion | 5.0 |
Serum lidocaine level measured via a blood test. Lidocaine has a therapeutic drug range of 1.5 to 5.0 mcg/mL. (NCT04208516)
Timeframe: 24 hours after surgery
| Intervention | mcg/mL (Mean) |
|---|---|
| Continuous Nerve Blocks | 2.5 |
Serum lidocaine level measured via a blood test. Lidocaine has a therapeutic drug range of 1.5 to 5.0 mcg/mL. (NCT04208516)
Timeframe: 48 hours after surgery
| Intervention | mcg/mL (Number) |
|---|---|
| Single Nerve Blocks Plus IV Lidocaine Infusion | 5.8 |
Serum lidocaine level measured via a blood test. Lidocaine has a therapeutic drug range of 1.5 to 5.0 mcg/mL. (NCT04208516)
Timeframe: 72 hours after surgery
| Intervention | mcg/mL (Number) |
|---|---|
| Single Nerve Blocks Plus IV Lidocaine Infusion | 1.5 |
Hospital length of stay is measured in days from admission until discharge. (NCT04208516)
Timeframe: From admission to discharge, on average 1-4 days
| Intervention | days (Mean) |
|---|---|
| Continuous Nerve Blocks | 9.04 |
| Single Nerve Blocks Plus IV Lidocaine Infusion | 4.94 |
5 reviews available for lidocaine and Cholera Infantum
| Article | Year |
|---|---|
Intravenous Lidocaine for Acute Pain: A Systematic Review.
Topics: Acute Pain; Anesthetics, Local; Gastrointestinal Diseases; Humans; Infusions, Intravenous; Lidocaine | 2018 |
Intravenous Lidocaine for Acute Pain: A Systematic Review.
Topics: Acute Pain; Anesthetics, Local; Gastrointestinal Diseases; Humans; Infusions, Intravenous; Lidocaine | 2018 |
Intravenous Lidocaine for Acute Pain: A Systematic Review.
Topics: Acute Pain; Anesthetics, Local; Gastrointestinal Diseases; Humans; Infusions, Intravenous; Lidocaine | 2018 |
Intravenous Lidocaine for Acute Pain: A Systematic Review.
Topics: Acute Pain; Anesthetics, Local; Gastrointestinal Diseases; Humans; Infusions, Intravenous; Lidocaine | 2018 |
Use of systemically administered lidocaine in horses with gastrointestinal tract disease.
Topics: Animals; Anti-Inflammatory Agents; Gastrointestinal Diseases; Horse Diseases; Horses; Ileus; Lidocai | 2008 |
Contemporary drug therapy in palliative care: new directions.
Topics: Adrenal Cortex Hormones; Analgesics; Anorexia; Antiemetics; Antitussive Agents; Cachexia; Cough; Dru | 2001 |
[Long-term treatment of arrhythmias].
Topics: Ajmaline; Arrhythmias, Cardiac; Ataxia; Electric Countershock; Gastrointestinal Diseases; Humans; Li | 1974 |
Digitalis intoxication--diagnosis, management and prevention.
Topics: Aged; Arrhythmias, Cardiac; Atrial Fibrillation; Atrioventricular Node; Digitalis Glycosides; Digoxi | 1974 |
4 trials available for lidocaine and Cholera Infantum
| Article | Year |
|---|---|
Perirenal space blocking restores gastrointestinal function in patients with severe acute pancreatitis.
Topics: Abdominal Pain; Acute Disease; Adult; Anesthetics, Local; Celiac Plexus; China; Female; Gastrointest | 2013 |
Propofol sedation alone or in combination with pharyngeal lidocaine anesthesia for routine upper GI endoscopy: a randomized, double-blind, placebo-controlled, non-inferiority trial.
Topics: Administration, Topical; Anesthesia, Local; Anesthetics, Intravenous; Anesthetics, Local; Conscious | 2011 |
Propofol sedation alone or in combination with pharyngeal lidocaine anesthesia for routine upper GI endoscopy: a randomized, double-blind, placebo-controlled, non-inferiority trial.
Topics: Administration, Topical; Anesthesia, Local; Anesthetics, Intravenous; Anesthetics, Local; Conscious | 2011 |
Propofol sedation alone or in combination with pharyngeal lidocaine anesthesia for routine upper GI endoscopy: a randomized, double-blind, placebo-controlled, non-inferiority trial.
Topics: Administration, Topical; Anesthesia, Local; Anesthetics, Intravenous; Anesthetics, Local; Conscious | 2011 |
Propofol sedation alone or in combination with pharyngeal lidocaine anesthesia for routine upper GI endoscopy: a randomized, double-blind, placebo-controlled, non-inferiority trial.
Topics: Administration, Topical; Anesthesia, Local; Anesthetics, Intravenous; Anesthetics, Local; Conscious | 2011 |
Propofol sedation alone or in combination with pharyngeal lidocaine anesthesia for routine upper GI endoscopy: a randomized, double-blind, placebo-controlled, non-inferiority trial.
Topics: Administration, Topical; Anesthesia, Local; Anesthetics, Intravenous; Anesthetics, Local; Conscious | 2011 |
Propofol sedation alone or in combination with pharyngeal lidocaine anesthesia for routine upper GI endoscopy: a randomized, double-blind, placebo-controlled, non-inferiority trial.
Topics: Administration, Topical; Anesthesia, Local; Anesthetics, Intravenous; Anesthetics, Local; Conscious | 2011 |
Propofol sedation alone or in combination with pharyngeal lidocaine anesthesia for routine upper GI endoscopy: a randomized, double-blind, placebo-controlled, non-inferiority trial.
Topics: Administration, Topical; Anesthesia, Local; Anesthetics, Intravenous; Anesthetics, Local; Conscious | 2011 |
Propofol sedation alone or in combination with pharyngeal lidocaine anesthesia for routine upper GI endoscopy: a randomized, double-blind, placebo-controlled, non-inferiority trial.
Topics: Administration, Topical; Anesthesia, Local; Anesthetics, Intravenous; Anesthetics, Local; Conscious | 2011 |
Propofol sedation alone or in combination with pharyngeal lidocaine anesthesia for routine upper GI endoscopy: a randomized, double-blind, placebo-controlled, non-inferiority trial.
Topics: Administration, Topical; Anesthesia, Local; Anesthetics, Intravenous; Anesthetics, Local; Conscious | 2011 |
Influence of gastrointestinal tract disease on pharmacokinetics of lidocaine after intravenous infusion in anesthetized horses.
Topics: Anesthesia; Anesthetics, Local; Animals; Female; Gastrointestinal Diseases; Horse Diseases; Horses; | 2006 |
Lidocaine lollipop as single-agent anesthesia in upper GI endoscopy.
Topics: Administration, Oral; Administration, Topical; Anesthetics, Local; Conscious Sedation; Dose-Response | 2007 |
10 other studies available for lidocaine and Cholera Infantum
| Article | Year |
|---|---|
Continuous Intravenous Lidocaine as an Effective Pain Adjunct for Opioid-Induced Bowel Dysfunction: A Case Report.
Topics: Abdominal Pain; Aged, 80 and over; Analgesics, Opioid; Anesthetics, Local; Failed Back Surgery Syndr | 2019 |
Clinical characteristics and patterns of healthcare utilization in patients with painful neuropathic disorders in UK general practice: a retrospective cohort study.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory Agents, Non-Stero | 2012 |
[Transendoscopic drug denervation of the stomach in emergency surgical diseases of the gastrointestinal tract (a preliminary report)].
Topics: Emergencies; Ethanol; Gastrointestinal Diseases; Gastroscopy; Humans; Lidocaine; Stomach; Sympathect | 1996 |
Xylocaine viscous as an aid in the differential diagnosis of chest pain.
Topics: Administration, Oral; Coronary Disease; Diagnosis, Differential; Gastrointestinal Diseases; Humans; | 1976 |
A caveat for xylocaine viscous and chest pain.
Topics: Coronary Disease; Gastrointestinal Diseases; Humans; Lidocaine; Pain; Thorax | 1976 |
Effects of topical anesthetic agents on Campylobacter pylori.
Topics: Administration, Topical; Anti-Bacterial Agents; Benzocaine; Campylobacter; Campylobacter Infections; | 1989 |
[Effect of peridural analgesia on pain and gastrointestinal syndromes in acute myocardial infarction].
Topics: Adult; Aged; Analgesia; Angina Pectoris; Female; Gastrointestinal Diseases; Humans; Injections, Epid | 1988 |
How to differentiate GI irritation from other causes of chest and upper abdominal pain.
Topics: Abdomen; Antacids; Chest Pain; Gastrointestinal Diseases; Humans; Lidocaine; Pain | 1988 |
[Clinical pharmacology and adverse effects of various anti-arrhythmic drugs].
Topics: Adrenergic beta-Antagonists; Aged; Anti-Arrhythmia Agents; Bone Marrow Diseases; Central Nervous Sys | 1971 |
[Letter: How to choose a gastrointestinal antispasmodic].
Topics: Aminophylline; Ampulla of Vater; Drug Therapy, Combination; Gastrointestinal Diseases; Humans; Lidoc | 1974 |