Page last updated: 2024-10-28

lidocaine and Cerebral Palsy

lidocaine has been researched along with Cerebral Palsy in 9 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Cerebral Palsy: A heterogeneous group of nonprogressive motor disorders caused by chronic brain injuries that originate in the prenatal period, perinatal period, or first few years of life. The four major subtypes are spastic, athetoid, ataxic, and mixed cerebral palsy, with spastic forms being the most common. The motor disorder may range from difficulties with fine motor control to severe spasticity (see MUSCLE SPASTICITY) in all limbs. Spastic diplegia (Little disease) is the most common subtype, and is characterized by spasticity that is more prominent in the legs than in the arms. Pathologically, this condition may be associated with LEUKOMALACIA, PERIVENTRICULAR. (From Dev Med Child Neurol 1998 Aug;40(8):520-7)

Research Excerpts

ExcerptRelevanceReference
"To investigate the effect of lidocaine epinephrine iontophoresis combined with exercises on gait and spasticity in children with spastic hemiplegic cerebral palsy (HCP)."9.34Effect of lidocaine iontophoresis combined with exercise intervention on gait and spasticity in children with spastic hemiplegic cerebral palsy: A randomized controlled trial. ( Aboelnasr, EA; Hegazy, FA; Salem, YT, 2020)
"To determine technical and clinical factors associated with pain when using an analgesic protocol with 50% nitrous oxide/oxygen and anesthetic cream (lidocaine and prilocaine, Emla(®)) for children with cerebral palsy undergoing botulinum toxin injections."9.15Determining the technical and clinical factors associated with pain for children undergoing botulinum toxin injections under nitrous oxide and anesthetic cream. ( Blajan, V; Brochard, S; Garlantezec, R; Houx, L; Le Moine, P; Lefranc, J; Lempereur, M; Peudenier, S; Rémy-Néris, O, 2011)
"Spastic diplegia is present in three-fourths of children with cerebral palsy, interfering with gait and frequently accompanied by severe pain."5.36Coupled obturator neurotomies and lidocaine intrathecal infusion to treat bilateral adductor spasticity and drug-refractory pain. ( Andrade, P; Carrillo-Ruiz, JD; Castro, G; Godínez-Cubillos, N; Jiménez, F; Montes-Castillo, ML; Velasco, AL; Velasco, F, 2010)
"Pain was evaluated with the Children's Hospital of Eastern Ontario Pain Scale (CHEOPS), the Visual Analogue Scale (VAS) and the Face Pain Scale (FPS) for the children and with a VAS for the parents."5.35Effectiveness of nitrous oxide and analgesic cream (lidocaine and prilocaine) for prevention of pain during intramuscular botulinum toxin injections in children. ( Blajan, V; Brochard, S; Le Moine, P; Lefranc, J; Lempereur, M; Peudenier, S; Rémy-Néris, O, 2009)
"To investigate the effect of lidocaine epinephrine iontophoresis combined with exercises on gait and spasticity in children with spastic hemiplegic cerebral palsy (HCP)."5.34Effect of lidocaine iontophoresis combined with exercise intervention on gait and spasticity in children with spastic hemiplegic cerebral palsy: A randomized controlled trial. ( Aboelnasr, EA; Hegazy, FA; Salem, YT, 2020)
"To determine technical and clinical factors associated with pain when using an analgesic protocol with 50% nitrous oxide/oxygen and anesthetic cream (lidocaine and prilocaine, Emla(®)) for children with cerebral palsy undergoing botulinum toxin injections."5.15Determining the technical and clinical factors associated with pain for children undergoing botulinum toxin injections under nitrous oxide and anesthetic cream. ( Blajan, V; Brochard, S; Garlantezec, R; Houx, L; Le Moine, P; Lefranc, J; Lempereur, M; Peudenier, S; Rémy-Néris, O, 2011)
"Treatment with lidocaine in pediatric cluster seizures may be useful and may be considered as a therapeutic option."1.51Long-term Outcome of Intravenous Lidocaine in Pediatric Cluster Seizures: A Preliminary Study. ( Jóźwiak, S; Strzelecka, J; Słowińska, M, 2019)
"Spastic diplegia is present in three-fourths of children with cerebral palsy, interfering with gait and frequently accompanied by severe pain."1.36Coupled obturator neurotomies and lidocaine intrathecal infusion to treat bilateral adductor spasticity and drug-refractory pain. ( Andrade, P; Carrillo-Ruiz, JD; Castro, G; Godínez-Cubillos, N; Jiménez, F; Montes-Castillo, ML; Velasco, AL; Velasco, F, 2010)
"Pain was evaluated with the Children's Hospital of Eastern Ontario Pain Scale (CHEOPS), the Visual Analogue Scale (VAS) and the Face Pain Scale (FPS) for the children and with a VAS for the parents."1.35Effectiveness of nitrous oxide and analgesic cream (lidocaine and prilocaine) for prevention of pain during intramuscular botulinum toxin injections in children. ( Blajan, V; Brochard, S; Le Moine, P; Lefranc, J; Lempereur, M; Peudenier, S; Rémy-Néris, O, 2009)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's2 (22.22)29.6817
2010's5 (55.56)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Hegazy, FA1
Aboelnasr, EA1
Salem, YT1
Strzelecka, J1
Słowińska, M1
Jóźwiak, S1
Brochard, S2
Blajan, V2
Lempereur, M2
Le Moine, P2
Peudenier, S2
Lefranc, J2
Rémy-Néris, O2
Carrillo-Ruiz, JD1
Andrade, P1
Godínez-Cubillos, N1
Montes-Castillo, ML1
Jiménez, F1
Velasco, AL1
Castro, G1
Velasco, F1
Garlantezec, R1
Houx, L1
Forrester, M1
Srinivasan, J1
Mihrshahi, S1
Waugh, M1
O'Flaherty, S1
Rice, J1
Graham, K1
Scheinberg, A1
Soudant, DL1
Staal, HM1
Witlox, AM1
Vles, JS1
Gambart, G1
Mette, F1
Pellot, AS1
Richard, I1
Saiki, K1
Tsuzuki, N1
Tanaka, R1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of the Effect of the Presence Of Clowns on Pain and Anxiety Seen During Injections Botulinum Toxin in Child[NCT03149263]80 participants (Actual)Observational2015-11-10Completed
Validity of Bispectral Index Monitoring During Deep Sedation for Botulinum Toxin Injection in Children With Cerebral Palsy[NCT02096549]22 participants (Actual)Observational2014-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for lidocaine and Cerebral Palsy

ArticleYear
Effect of lidocaine iontophoresis combined with exercise intervention on gait and spasticity in children with spastic hemiplegic cerebral palsy: A randomized controlled trial.
    NeuroRehabilitation, 2020, Volume: 47, Issue:2

    Topics: Cerebral Palsy; Child; Child, Preschool; Electromyography; Exercise Therapy; Female; Gait; Gait Diso

2020
Determining the technical and clinical factors associated with pain for children undergoing botulinum toxin injections under nitrous oxide and anesthetic cream.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2011, Volume: 15, Issue:4

    Topics: Administration, Topical; Adolescent; Anesthetics, Local; Botulinum Toxins, Type A; Cerebral Palsy; C

2011
[Evaluation of analgesic protocol with nitrous oxide and EMLA cream during botulinum toxin injections in children].
    Annales de readaptation et de medecine physique : revue scientifique de la Societe francaise de reeducation fonctionnelle de readaptation et de medecine physique, 2007, Volume: 50, Issue:5

    Topics: Adolescent; Analgesics, Non-Narcotic; Anesthetics, Local; Botulinum Toxins, Type A; Cerebral Palsy;

2007

Other Studies

6 other studies available for lidocaine and Cerebral Palsy

ArticleYear
Long-term Outcome of Intravenous Lidocaine in Pediatric Cluster Seizures: A Preliminary Study.
    Pediatric neurology, 2019, Volume: 97

    Topics: Adolescent; Anticonvulsants; Arrhythmias, Cardiac; Cerebral Palsy; Child; Child, Preschool; Drug Eva

2019
Effectiveness of nitrous oxide and analgesic cream (lidocaine and prilocaine) for prevention of pain during intramuscular botulinum toxin injections in children.
    Annals of physical and rehabilitation medicine, 2009, Volume: 52, Issue:10

    Topics: Administration, Cutaneous; Administration, Inhalation; Adolescent; Anesthetics; Anti-Dyskinesia Agen

2009
Coupled obturator neurotomies and lidocaine intrathecal infusion to treat bilateral adductor spasticity and drug-refractory pain.
    Journal of neurosurgery, 2010, Volume: 113, Issue:3

    Topics: Adult; Anesthetics, Local; Cerebral Palsy; Female; Fetal Hypoxia; Follow-Up Studies; Humans; Infusio

2010
Conscious sedation or general anaesthetic for intramuscular botulinum toxin injections in children - a two centre cross-sectional prospective audit.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2012, Volume: 16, Issue:2

    Topics: Botulinum Toxins, Type A; Cerebral Palsy; Female; Humans; Lidocaine; Male; Nitrous Oxide; Pain; Para

2012
Conscious sedation or general anaesthetic for intramuscular botulinum toxin injections in children - a two centre cross-sectional prospective audit.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2013, Volume: 17, Issue:2

    Topics: Botulinum Toxins, Type A; Cerebral Palsy; Female; Humans; Lidocaine; Male; Nitrous Oxide; Pain; Para

2013
The effect of muscle-tone-reducing procedures in athetotic head movements: partial nerve block by lidocaine and surgical release of the neck muscles.
    Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 1999, Volume: 110, Issue:7

    Topics: Adult; Cerebral Palsy; Electromyography; Female; Head Movements; Humans; Lidocaine; Male; Middle Age

1999