Page last updated: 2024-10-28

lidocaine and Cataract, Membranous

lidocaine has been researched along with Cataract, Membranous in 32 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Research Excerpts

ExcerptRelevanceReference
"02%), and lidocaine (1%) intracamerally was used for mydriasis and analgesia."9.51Evaluation of efficacy of intracameral lidocaine and tropicamide injection in manual small-incision cataract surgery: A prospective clinical study. ( Bhat, KT; Heda, AS; Undre, AA; Wadgaonkar, SP, 2022)
"31%/lidocaine 1% in pediatric cataract surgery, a combination widely used in adult patients but still off-label in children."8.31Efficacy and safety of intraoperative use of tropicamide 0.02%/phenylephrine0.31%/lidocaine1% intracameral combination during pediatric cataract surgery. ( Caputo, R; Dellavalle, A; Lembo, A; Nucci, P; Pichi, F; Schiavetti, I; Serafino, M, 2023)
"To compare the efficacy of ropivacaine with a mixture of lidocaine and bupivacaine in peribulbar anesthesia for cataract surgery, in terms of post-block intraocular pressure (IOP)."8.12Comparative study to assess the effect of ropivacaine and a mixture of lidocaine and bupivacaine on intraocular pressure after peribulbar anesthesia for cataract surgery. ( Bubanale, SC; Jain, E, 2022)
"To assess whether preservative-free 1% lidocaine is capable of destroying the LECs in age-related cataract (ARC) in order to provide scientific basis for pursuing safe and effective drugs to eliminate LECs in cataract surgery."7.74[Pathological study on effects of preservative-free 1% lidocaine on lens epithelial cells of patients with age-related cataract]. ( Duan, HX; Guan, HJ; Wu, J; Zhu, RR, 2008)
"02%), and lidocaine (1%) intracamerally was used for mydriasis and analgesia."5.51Evaluation of efficacy of intracameral lidocaine and tropicamide injection in manual small-incision cataract surgery: A prospective clinical study. ( Bhat, KT; Heda, AS; Undre, AA; Wadgaonkar, SP, 2022)
"31% and lidocaine 1%) and mydriatic drops (tropicamide 1% and phenylephrine 10%) used for cataract surgery in terms of efficacy in pupil dilation and impact on corneal endothelial cell density (CD) and central corneal thickness (CCT)."5.34Mydrane intracameral injection site can be an alternative to mydriatic drops instillation in cataract surgery. ( Bolsega-Pacud, J; Kubicka-Trzaska, A; Markiewicz, A; Nazim-Lipski, G; Romanowska-Dixon, B, 2020)
"In a double-masked, controlled trial, 48 eyes of 48 patients with uncomplicated age-related cataract were randomly assigned to receive bupivacaine 0."5.09Comparison of preservative-free bupivacaine vs. lidocaine for intracameral anesthesia: a randomized clinical trial and in vitro analysis. ( Anderson, CJ; Anderson, NJ; Edelhauser, HF; Nath, R, 1999)
"We evaluated, in a real-life setting, the effect of Mydrane® (ready-to-use combination of tropicamide, phenylephrine hydrochloride and lidocaine, injected into the anterior chamber at the beginning of cataract surgery to induce mydriasis and intraocular anaesthesia) on the pupil diameter during cataract surgery in patients with a preoperative pupil diameter <6 mm after the use of topical mydriatics."4.31Pupil diameter during cataract surgery after intracameral injection of the first ready-to-use combination of mydriatics and anaesthetic at the beginning of surgery in patients with a preoperative pupil diameter <6 mm. ( Grabska-Liberek, I; Jurowski, P; Kęcik, D; Kopacz, D; Mianowska, K; Mrukwa-Kominek, E; Omulecki, W; Romaniuk, W; Romanowska-Dixon, B; Szaflik, J; Szaflik, JP, 2023)
"31%/lidocaine 1% in pediatric cataract surgery, a combination widely used in adult patients but still off-label in children."4.31Efficacy and safety of intraoperative use of tropicamide 0.02%/phenylephrine0.31%/lidocaine1% intracameral combination during pediatric cataract surgery. ( Caputo, R; Dellavalle, A; Lembo, A; Nucci, P; Pichi, F; Schiavetti, I; Serafino, M, 2023)
"To compare the efficacy of ropivacaine with a mixture of lidocaine and bupivacaine in peribulbar anesthesia for cataract surgery, in terms of post-block intraocular pressure (IOP)."4.12Comparative study to assess the effect of ropivacaine and a mixture of lidocaine and bupivacaine on intraocular pressure after peribulbar anesthesia for cataract surgery. ( Bubanale, SC; Jain, E, 2022)
"To evaluate changes in clinical outcomes, duration, and workflow of cataract surgery, before and after the introduction of a commercially available intracameral combination of 2 mydriatics (phenylephrine, tropicamide) and 1 anesthetic (lidocaine) (ICMA)."3.96Assessment of the duration of surgery and patient turnover after the incorporation of a standardized intracameral combination of mydriatics and anesthetics for cataract surgery. ( Barreau, E; Ben Hadj Salah, W; Best, AL; Labetoulle, M; M'garrech, M; Rousseau, A, 2020)
"To assess whether preservative-free 1% lidocaine is capable of destroying the LECs in age-related cataract (ARC) in order to provide scientific basis for pursuing safe and effective drugs to eliminate LECs in cataract surgery."3.74[Pathological study on effects of preservative-free 1% lidocaine on lens epithelial cells of patients with age-related cataract]. ( Duan, HX; Guan, HJ; Wu, J; Zhu, RR, 2008)
"Implantation of an IOL at the time of cataract extraction under combined systemic ketamine and peribulbar lidocaine anesthesia appeared to be well tolerated and produced significant visual improvement in pediatric patients in Nepal."3.72Pediatric cataract surgery in Nepal. ( Gurung, R; Paudyal, G; Reddy, H; Ruit, S; Tabin, G; Thakur, J; Thapa, S; Wilson, ME, 2004)
"In this prospective study, topical anesthesia with 2% lidocaine hydrochloride jelly without systemic sedation was used for combined phacoemulsification, posterior chamber intraocular lens implantation, and trabeculectomy in consecutive patients with primary open-angle glaucoma and concurrent cataract at the United Christian Hospital, Kowloon, Hong Kong, from September 2000 to May 2001."3.71Topical anesthesia in phacotrabeculectomy. ( Lai, JS; Lam, DS; Tham, CC, 2002)
" Postoperative safety included adverse events, endothelial cell density and vision."2.94Safety and efficacy of a standardized intracameral combination of mydriatics and anesthetic for cataract surgery in type-2 diabetic patients. ( Behndig, A; Bérard, A; Chiambaretta, F; Cochener-Lamard, B; Güell, JL; Labetoulle, M; Mencucci, R; Nuijts, R; Pleyer, U; Rosen, P; Szaflik, J; Tassignon, MJ, 2020)
"The pain was evaluated at the time of administration of the block, during the surgery, and during the postoperative period of 4 h."1.72A comparison of sub-tenon block with peribulbar block in small-incision cataract surgery. ( Antony, RM; Jeganathan, S; Kamath, AR; Rodrigues, GR, 2022)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (6.25)18.2507
2000's10 (31.25)29.6817
2010's4 (12.50)24.3611
2020's16 (50.00)2.80

Authors

AuthorsStudies
Zaluski, S1
Amzallag, T1
Bouchut, P1
Pinsard, L1
Theron, JP1
Tellouck-Morincomme, J1
Baffert, S1
Kęcik, D1
Grabska-Liberek, I1
Jurowski, P1
Mrukwa-Kominek, E1
Omulecki, W1
Romanowska-Dixon, B2
Szaflik, JP1
Romaniuk, W1
Szaflik, J2
Kopacz, D1
Mianowska, K1
Nucci, P1
Lembo, A1
Caputo, R1
Dellavalle, A1
Serafino, M1
Schiavetti, I1
Pichi, F1
Antony, RM1
Kamath, AR1
Jeganathan, S1
Rodrigues, GR1
Jain, E1
Bubanale, SC1
Kumari, K1
Kaur, S1
Sukhija, J1
Bhat, KT1
Wadgaonkar, SP1
Undre, AA1
Heda, AS1
Ripa, M1
Cuffaro, G1
Savastano, MC1
Grieco, G1
Rizzo, S1
Ricci, F1
Mohankumar, A1
Rajan, M1
Deeks, ED1
Labetoulle, M3
Behndig, A1
Tassignon, MJ1
Nuijts, R1
Mencucci, R1
Güell, JL2
Pleyer, U1
Rosen, P1
Bérard, A1
Chiambaretta, F1
Cochener-Lamard, B1
Nazim-Lipski, G1
Bolsega-Pacud, J1
Kubicka-Trzaska, A1
Markiewicz, A1
Ben Hadj Salah, W1
Rousseau, A1
M'garrech, M1
Best, AL1
Barreau, E1
Souki, S1
Cochener, B1
Simons, RWP1
Rondas, LUE1
van den Biggelaar, FJHM1
Berendschot, TTJM1
Visser, N1
de Crom, RMPC1
Nuijts, RMMA1
Suresha, AR1
Gunashree, KN1
Maharjan, I1
Shrestha, E1
Gurung, B1
Gurung, HM1
Adhikari, HB1
Baral, P1
Tutchenko, LP1
Znamens'ka, MA1
Dzhulaĭ, MV1
Dzhulaĭ, IM1
Lartey, S1
Armah, P1
Ampong, A1
Coşkun, M1
Dağlioğlu, MC1
Davran, R1
Ilhan, N1
Ilhan, O1
Ayhan Tuzcu, E1
Ayintap, E1
Keskin, U1
Oksüz, H1
Guan, HJ1
Duan, HX1
Wu, J1
Zhu, RR1
Lai, JS1
Tham, CC1
Lam, DS1
Vargas, LG1
Escobar-Gomez, M1
Apple, DJ1
Hoddinott, DS1
Schmidbauer, JM1
Gills, JP1
Thakur, J1
Reddy, H1
Wilson, ME1
Paudyal, G1
Gurung, R1
Thapa, S1
Tabin, G1
Ruit, S1
Werner, L1
Pandey, SK1
Izak, AM1
Hickman, MS1
LeBoyer, RM1
Mamalis, N1
Ashwin, PT1
Tambe, K1
Quinlan, M1
Belfort, R1
Muccioli, C1
Anderson, NJ1
Nath, R1
Anderson, CJ1
Edelhauser, HF1
Silvera, D1
Michaeli-Cohen, A1
Slomovic, AR1
Jacobi, PC1
Dietlein, TS1
Jacobi, FK1
Rebolleda, G1
Muñoz-Negrete, FJ1
Gutierrez-Ortiz, C1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy of the Intracamerally Administered Mydriatics for Cataract Surgery in Patients With Primary Open-angle Glaucoma.[NCT05925894]60 participants (Actual)Interventional2021-03-18Completed
Efficacy and Safety Assessment of Intracameral Injection of T2380 in Cataract Surgery Versus Reference Group (Topical Mydriatics and Anaesthetic)[NCT02101359]Phase 3609 participants (Actual)Interventional2011-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

The Primary Efficacy Variable is Response Based on the Realisation of the Capsulorhexis Without Use of Any Additive Mydriatic Treatment.

(NCT02101359)
Timeframe: Day 0

Interventionpercentage of responders (Number)
T238098.9
Reference Group94.7

Reviews

1 review available for lidocaine and Cataract, Membranous

ArticleYear
Role of hyaluronidase as an adjuvant in local anesthesia for cataract surgery.
    Indian journal of ophthalmology, 2023, Volume: 71, Issue:7

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Cataract; Cataract Extraction; Cattle; Child; Humans

2023

Trials

8 trials available for lidocaine and Cataract, Membranous

ArticleYear
Evaluation of efficacy of intracameral lidocaine and tropicamide injection in manual small-incision cataract surgery: A prospective clinical study.
    Indian journal of ophthalmology, 2022, Volume: 70, Issue:11

    Topics: Cataract; Humans; Lidocaine; Mydriasis; Mydriatics; Phacoemulsification; Phenylephrine; Prospective

2022
Tropicamide/Phenylephrine/Lidocaine Intracameral Injection: A Review in Cataract Surgery.
    Clinical drug investigation, 2019, Volume: 39, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Cataract; Cataract Extraction; Drug Combinations; Drug Therapy, Comb

2019
Safety and efficacy of a standardized intracameral combination of mydriatics and anesthetic for cataract surgery in type-2 diabetic patients.
    BMC ophthalmology, 2020, Mar-03, Volume: 20, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anterior Chamber; Cataract; Diabetes Mellitus, T

2020
Safety and efficacy of a standardized intracameral combination of mydriatics and anesthetic for cataract surgery in type-2 diabetic patients.
    BMC ophthalmology, 2020, Mar-03, Volume: 20, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anterior Chamber; Cataract; Diabetes Mellitus, T

2020
Safety and efficacy of a standardized intracameral combination of mydriatics and anesthetic for cataract surgery in type-2 diabetic patients.
    BMC ophthalmology, 2020, Mar-03, Volume: 20, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anterior Chamber; Cataract; Diabetes Mellitus, T

2020
Safety and efficacy of a standardized intracameral combination of mydriatics and anesthetic for cataract surgery in type-2 diabetic patients.
    BMC ophthalmology, 2020, Mar-03, Volume: 20, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anterior Chamber; Cataract; Diabetes Mellitus, T

2020
Mydrane intracameral injection site can be an alternative to mydriatic drops instillation in cataract surgery.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2020, Volume: 71, Issue:2

    Topics: Aged; Aged, 80 and over; Cataract; Cataract Extraction; Female; Humans; Injections, Intraocular; Lid

2020
Phase IV clinical study to evaluate the effects of an intracameral combined mydriatic and anesthetic agent and standard topical mydriatics and anesthetics on the ocular surface after cataract surgery.
    Journal of cataract and refractive surgery, 2021, May-01, Volume: 47, Issue:5

    Topics: Anesthetics, Local; Cataract; Humans; Lidocaine; Mydriatics; Ophthalmic Solutions; Prospective Studi

2021
Comparison of preservative-free bupivacaine vs. lidocaine for intracameral anesthesia: a randomized clinical trial and in vitro analysis.
    American journal of ophthalmology, 1999, Volume: 127, Issue:4

    Topics: Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Animals; Anterior Chamber; Bupivacai

1999
Cataract surgery under topical anesthesia in patients with coexisting glaucoma.
    Journal of cataract and refractive surgery, 2001, Volume: 27, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Cataract; Chronic Disease; Fe

2001
Topical plus intracameral lidocaine versus retrobulbar anesthesia in phacotrabeculectomy: prospective randomized study.
    Journal of cataract and refractive surgery, 2001, Volume: 27, Issue:8

    Topics: Administration, Topical; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Anterior Ch

2001

Other Studies

23 other studies available for lidocaine and Cataract, Membranous

ArticleYear
Perioperative time and economic impact of an intracameral combination of mydriatics and anaesthetics in routine cataract surgery.
    European journal of ophthalmology, 2023, Volume: 33, Issue:1

    Topics: Anesthetics, Local; Cataract; Cataract Extraction; Humans; Lidocaine; Mydriatics; Ophthalmic Solutio

2023
Pupil diameter during cataract surgery after intracameral injection of the first ready-to-use combination of mydriatics and anaesthetic at the beginning of surgery in patients with a preoperative pupil diameter <6 mm.
    Acta ophthalmologica, 2023, Volume: 101, Issue:1

    Topics: Anesthetics; Cataract; Humans; Lidocaine; Mydriasis; Mydriatics; Ophthalmic Solutions; Phacoemulsifi

2023
Efficacy and safety of intraoperative use of tropicamide 0.02%/phenylephrine0.31%/lidocaine1% intracameral combination during pediatric cataract surgery.
    International ophthalmology, 2023, Volume: 43, Issue:3

    Topics: Adult; Cataract; Child; Humans; Lidocaine; Mydriasis; Mydriatics; Ophthalmology; Phacoemulsification

2023
A comparison of sub-tenon block with peribulbar block in small-incision cataract surgery.
    Indian journal of ophthalmology, 2022, Volume: 70, Issue:11

    Topics: Anesthesia, Local; Anesthetics, Local; Cataract; Cataract Extraction; Humans; India; Lidocaine; Opht

2022
Comparative study to assess the effect of ropivacaine and a mixture of lidocaine and bupivacaine on intraocular pressure after peribulbar anesthesia for cataract surgery.
    Indian journal of ophthalmology, 2022, Volume: 70, Issue:11

    Topics: Amides; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Cataract; Cataract Extraction; Humans; I

2022
Commentary: Intracameral mydriatics in cataract surgery.
    Indian journal of ophthalmology, 2022, Volume: 70, Issue:11

    Topics: Anterior Chamber; Cataract; Cataract Extraction; Humans; Lens, Crystalline; Lidocaine; Mydriatics; P

2022
Efficacy of the intracamerally administered mydriatics for cataract surgery in patients with primary open-angle glaucoma.
    European journal of ophthalmology, 2023, Volume: 33, Issue:3

    Topics: Cataract; Cataract Extraction; Glaucoma, Open-Angle; Humans; Lidocaine; Mydriatics; Ophthalmic Solut

2023
Assessment of the duration of surgery and patient turnover after the incorporation of a standardized intracameral combination of mydriatics and anesthetics for cataract surgery.
    Journal of cataract and refractive surgery, 2020, Volume: 46, Issue:11

    Topics: Anesthetics, Local; Cataract; France; Humans; Lidocaine; Mydriatics; Phacoemulsification; Prospectiv

2020
Cost analysis of mydriasis strategies in cataract surgery care in the Netherlands.
    Journal of cataract and refractive surgery, 2021, 08-01, Volume: 47, Issue:8

    Topics: Cataract; Costs and Cost Analysis; Humans; Lidocaine; Mydriasis; Mydriatics; Netherlands; Phacoemuls

2021
Safety and efficacy of intracameral mydriatics: Lignocaine and epinephrine in manual small-incision cataract surgery and their effect on blood pressure and heart rate.
    Indian journal of ophthalmology, 2021, Volume: 69, Issue:5

    Topics: Anterior Chamber; Blood Pressure; Cataract; Cataract Extraction; Epinephrine; Heart Rate; Humans; Li

2021
Pain Perception in Cataract Surgery: Topical versus Peribulbar Anaesthesia.
    Nepalese journal of ophthalmology : a biannual peer-reviewed academic journal of the Nepal Ophthalmic Society : NEPJOPH, 2021, Volume: 13, Issue:25

    Topics: Anesthesia, Local; Anesthetics, Local; Bupivacaine; Cataract; Female; Humans; Lidocaine; Male; Pain

2021
[Investigation of the influence of intracameral injection of domestic lidocaine on the corneal thickness during phacoemulsification of cataract].
    Likars'ka sprava, 2012, Issue:8

    Topics: Adult; Anesthesia, Local; Anesthetics, Local; Anterior Chamber; Cataract; Cornea; Female; Humans; Hy

2012
A sudden total loss of vision after routine cataract surgery.
    Ghana medical journal, 2013, Volume: 47, Issue:2

    Topics: Anesthesia, Local; Anti-Bacterial Agents; Blindness; Cataract; Cataract Extraction; Epinephrine; Fem

2013
Effects of sub-Tenon's anaesthesia on ocular hemodynamics.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2014, Volume: 49, Issue:2

    Topics: Aged; Anesthesia, Local; Anesthetics, Local; Blood Flow Velocity; Cataract; Epinephrine; Female; Hum

2014
[Pathological study on effects of preservative-free 1% lidocaine on lens epithelial cells of patients with age-related cataract].
    [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 2008, Volume: 44, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Aging; Cataract; Epithelial Cells; Female; Humans; Lens, Crystalline

2008
Topical anesthesia in phacotrabeculectomy.
    Journal of glaucoma, 2002, Volume: 11, Issue:3

    Topics: Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Cataract; Female; Gels; Glaucoma, Op

2002
Pharmacologic prevention of posterior capsule opacification: in vitro effects of preservative-free lidocaine 1% on lens epithelial cells.
    Journal of cataract and refractive surgery, 2003, Volume: 29, Issue:8

    Topics: Anesthetics, Local; Animals; Anthraquinones; Cataract; Epithelial Cells; Female; Lens Capsule, Cryst

2003
Effect of lidocaine on lens epithelial cells.
    Journal of cataract and refractive surgery, 2004, Volume: 30, Issue:6

    Topics: Anesthetics, Local; Animals; Cataract; Epithelial Cells; Lens Capsule, Crystalline; Lidocaine; Posto

2004
Pediatric cataract surgery in Nepal.
    Journal of cataract and refractive surgery, 2004, Volume: 30, Issue:8

    Topics: Adolescent; Anesthesia, General; Anesthetics, Dissociative; Anesthetics, Local; Blindness; Cataract;

2004
Evaluation of the cataractogenic effect of viscoanesthetic solutions on the rabbit crystalline lens.
    Journal of cataract and refractive surgery, 2005, Volume: 31, Issue:7

    Topics: Anesthetics, Local; Animals; Anterior Chamber; Cataract; Drug Combinations; Hyaluronic Acid; Injecti

2005
Unusual presentation of Amsler's sign in Fuchs' heterochromic uveitis.
    Journal of cataract and refractive surgery, 2006, Volume: 32, Issue:9

    Topics: Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Blood Pressure; Bupivacaine; Cataract;

2006
Hyphema after peribulbar anesthesia for cataract surgery in Fuchs' heterochromic iridocyclitis.
    Ocular immunology and inflammation, 1998, Volume: 6, Issue:1

    Topics: Adult; Anesthetics, Local; Cataract; Cataract Extraction; Female; Humans; Hyphema; Intraoperative Co

1998
Topical plus intracameral anesthesia for a triple procedure (penetrating keratoplasty, phacoemulsification and lens implantation).
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2000, Volume: 35, Issue:6

    Topics: Aged; Anesthesia, Local; Anesthetics, Local; Anterior Chamber; Cataract; Drug Therapy, Combination;

2000