Page last updated: 2024-10-28

lidocaine and Cardiovascular Diseases

lidocaine has been researched along with Cardiovascular Diseases in 31 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.

Research Excerpts

ExcerptRelevanceReference
"Four hundred two patients with suspected myocardial infarction seen within 6 hours of the onset of symptoms entered a double-blind randomized trial of lidocaine vs placebo."9.05Prophylactic lidocaine in the early phase of suspected myocardial infarction. ( Adgey, AA; Campbell, NP; Dunn, HM; Kinney, CD; MacKenzie, G; McComb, JM; Shanks, RG, 1985)
"The routine use of fentanyl and midazolam prior to sheath removal leads to a reduction in pain perception and vasovagal incidence, whilst the routine use of local infiltration during sheath removal should be discouraged as it leads to more pain and a trend to more vasovagal reactions."5.12Effect of local anesthesia and intravenous sedation on pain perception and vasovagal reactions during femoral arterial sheath removal after percutaneous coronary intervention. ( French, JK; Juergens, CP; Kiat Ang, C; Leung, DY; Lo, S, 2007)
"Four hundred two patients with suspected myocardial infarction seen within 6 hours of the onset of symptoms entered a double-blind randomized trial of lidocaine vs placebo."5.05Prophylactic lidocaine in the early phase of suspected myocardial infarction. ( Adgey, AA; Campbell, NP; Dunn, HM; Kinney, CD; MacKenzie, G; McComb, JM; Shanks, RG, 1985)
"Lidocaine 2% was administered to eight dogs before surgery in differing amounts, depending on the volume of the joints involved, and blood samples were taken at predetermined time points."2.80Intra-articular administration of lidocaine in anaesthetized dogs: pharmacokinetic profile and safety on cardiovascular and nervous systems. ( Bufalari, A; Cagnardi, P; Catanzaro, A; De Monte, V; Della Rocca, G; Di Salvo, A; Marenzoni, ML; Vigorito, V, 2015)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199017 (54.84)18.7374
1990's1 (3.23)18.2507
2000's7 (22.58)29.6817
2010's5 (16.13)24.3611
2020's1 (3.23)2.80

Authors

AuthorsStudies
Zhu, K1
Yan, T1
Qin, C1
Pan, Y1
Li, J1
Lai, H1
Xu, D1
Wang, C1
Hu, N1
Di Salvo, A1
Bufalari, A1
De Monte, V1
Cagnardi, P1
Marenzoni, ML1
Catanzaro, A1
Vigorito, V1
Della Rocca, G1
Dadak, AM1
Franz, S1
Jäger, W1
Tichy, A1
Baumgartner, W1
Mosing, M1
Dobson, GP1
Pham, DT1
Castello, R1
Hammon, JW1
Wolfe, JW1
Butterworth, JF1
Lotufo, PA1
WELFLING, J1
Breunig, J1
Kiat Ang, C1
Leung, DY1
Lo, S1
French, JK1
Juergens, CP1
Gunnar, RM1
Lambrew, CT1
Abrams, W1
Adolph, RJ1
Chatterjee, K1
Cohn, JN1
Derryberry, JS1
Horowitz, LN1
Martin, WB1
Siciliano, EG1
Temple, R1
Tuckman, J1
Drake, CE1
Caride, VJ1
Bunting, HE1
Kelly, MC1
Milligan, KR1
Caron, MF1
Song, J1
White, CM1
Singh, BN1
Niwa, H1
Sugimura, M1
Satoh, Y1
Tanimoto, A1
Guntheroth, W1
Whitcomb, DC1
Gilliam, FR1
Starmer, CF1
Grant, AO1
Covino, BG1
Yang, MW1
Lee, TY1
Chan, KH1
Chung, SK1
Dunn, HM1
McComb, JM1
Kinney, CD1
Campbell, NP1
Shanks, RG1
MacKenzie, G1
Adgey, AA1
Cantele, P1
Manani, G1
Cirillo, FM1
Pizzirani, E1
Bortoluzzi, A1
Hendrix, GH1
Cline, ME1
Raisfeld, IH1
Thomson, PD1
Geddes, IC1
Slama, R1
Motte, G1
Gourgon, R1
Passa, P1
Bouvrain, Y1

Clinical Trials (7)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Fractional Carbon Dioxide Laser Assisted Delivery of Topical Anesthetics: a Randomized Controlled Pilot Study[NCT02246179]Phase 410 participants (Actual)Interventional2014-09-30Completed
Parameters in Fractional Laser Assisted Delivery of Topical Anesthetics: Role of Anesthetic and Application Time[NCT03279757]Phase 415 participants (Actual)Interventional2016-10-01Completed
Parameters in Fractional Laser Assisted Delivery of Topical Anesthetics: Role of Laser Type and Laser Settings[NCT02938286]Phase 415 participants (Actual)Interventional2016-03-31Completed
Fractional CO2 Laser Assisted Topical Articaine Anesthesia vs. Topical EMLA Administration: a Randomized Controlled Study[NCT02548533]Phase 43 participants (Actual)Interventional2015-06-30Terminated (stopped due to Not enough patients eligible for recruitment.)
Prospective Randomized Trial of Penile Nerve Block With Liposomal Bupivacaine for Hypospadias Repair vs Standard Penile Block With Bupivacaine[NCT04479371]Phase 10 participants (Actual)Interventional2021-07-31Withdrawn (stopped due to Limited funding and resources to complete FDA requirements for enrollment)
Use of Preemptive Pudendal Nerve Block Prior to Hydrodistension for the Treatment of Interstitial Cystitis/Painful Bladder Syndrome (IC/PBS): a Prospective, Double-blinded, Randomized Control Trial[NCT02517996]18 participants (Actual)Interventional2015-02-28Terminated (stopped due to Preliminary results were promising when interim analysis performed but terminated due to primary investigators left recruitment site.)
Maternal-Fetal Monitoring of Patients With Rheumatic Heart Disease During Dental Procedure Under Local Anesthesia[NCT00482573]Phase 131 participants (Actual)Interventional2004-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in IC Symptom Index Questionnaire With Preemptive Pudendal Nerve Block Compared to Saline

"To determine the change in interstitial cystitis symptom index at baseline, 2 hours, 2 weeks, 6 weeks and 3 months after hydrodistention with preemptive pudendal nerve block (1% Lidocaine) compared to hydrodistention with placebo (saline).~The IC symptom index questionnaire consists of 4 questions on IC symptoms. 2 of the questions have 6 answer choices ranging from 0-never, to 5-almost always. 1 question has 6 answer choices ranging from 0-never to 5-usually. 1 question has 7 answer choices ranging from 0-never to 6-5 or more times. The numerical score for each question are added together, with a minimum score of 0 and a maximum score of 21. A higher score indicates greater severity of IC symptoms." (NCT02517996)
Timeframe: Baseline, 2 weeks, 6 weeks, 3 months (Up to 3 months)

,
Interventionscore on a scale (Mean)
Baseline2 weeks6 weeks12 weeks
1% Lidocaine12.511.4311.810
Normal Saline1098.675

Change in Pain Level as Assessed by the Visual Analog Scale (VAS)

"To determine the change in pain at 2 hours, 2 weeks, 6 weeks, and 3 months postoperatively in patients undergoing hydrodistention with preemptive pudendal nerve block (1% Lidocaine) compared to hydrodistention with placebo (saline) using the visual analog scale (VAS).~VAS consists of a 10cm horizontal line with the minimum endpoint labeled no pain (0) and maximum labeled worst pain ever (10). Patients placed a mark on the point that corresponds to the level of pain severity they felt. The cm distance from the low end of the VAS to the patient's mark is used as the numerical index of the intensity of pain. Pain scores of 3.0-5.4 cm are moderate, over 5.4 indicates severe pain." (NCT02517996)
Timeframe: Baseline, 2 hours, 2 weeks, 6 weeks, 3 months (Up to 3 months)

,
Interventionscore on a scale (Mean)
Pre operative VAS scorePost operative VAS score2 week post operative VAS scores6 week post operative VAS score12 weeks post operative VAS score
1% Lidocaine3.1253.752.732.6
Normal Saline4.554.84.332

Change in Pelvic Urgency, Pain, and Frequency (PUF) Questionnaire With Preemptive Pudendal Nerve Block Compared to Saline

"To determine the change in pelvic urgency, pain and frequency (PUF) questionnaire at baseline, 2 hours, 2 weeks, 6 weeks and 3 months after hydrodistention with preemptive pudendal nerve block (1% Lidocaine) compared to hydrodistention with placebo (saline).~The Pelvic Urgency, Pain, and Frequency Patient Symptom Scale asks 11 questions, 7 on PUF symptoms, 4 on how bothersome PUF symptoms are. Symptom questions include 3, 4, or 5 ranked answers, with higher answers indicating more voids, or greater frequency of pain. The bother questions each of 4 ranked answers from 0-never, to 3-always. The symptom score is added, the bother score is added, and then the total score is added. The total PUF score is then reported. The minimum score is 0 and the maximum score is 35, and a higher score indicates greater symptoms and higher bother from pelvic pain and frequency." (NCT02517996)
Timeframe: Baseline, 2 hours, 2 weeks, 6 weeks, 3 months (Up to 3 months)

,
Interventionscore on a scale (Mean)
Baseline2 weeks6 weeks12 weeks
1% Lidocaine22.6318.8318.217.2
Normal Saline1917.416.714

Change in Problem Index (O'Leary Sant) With Preemptive Pudendal Nerve Block Compared to Saline

"To determine the change in problem index (O'Leary Sant) at baseline, 2 hours, 2 weeks, 6 weeks and 3 months after hydrodistention with preemptive pudendal nerve block (1% Lidocaine) compared to hydrodistention with placebo (saline).~The IC problem index questionnaire consists of 4 questions on how much of a problem a patient's IC symptoms cause them. Each question has 5 answer choices ranging from 0-no problem, to 4-big problem. The numerical score for each question are added together, with a minimum score of 0 and a maximum score of 16. A higher score indicates that IC symptoms cause more problems for the patient." (NCT02517996)
Timeframe: Baseline, 2 hours, 2 weeks, 6 weeks, 3 months (Up to 3 months)

,
Interventionscore on a scale (Mean)
Baseline2 weeks6 weeks12 weeks
1% Lidocaine11.759.71109.6
Normal Saline9.438.67.336

Reviews

7 reviews available for lidocaine and Cardiovascular Diseases

ArticleYear
[Topical anaesthesia in cataract surgery].
    Klinische Monatsblatter fur Augenheilkunde, 2010, Volume: 227, Issue:8

    Topics: Aged; Anesthesia, Local; Anesthetics, Local; Anterior Chamber; Cardiovascular Diseases; Cataract Ext

2010
Local anesthetic systemic toxicity: update on mechanisms and treatment.
    Current opinion in anaesthesiology, 2011, Volume: 24, Issue:5

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular Diseases; Disease Models

2011
Local anesthetic systemic toxicity: update on mechanisms and treatment.
    Current opinion in anaesthesiology, 2011, Volume: 24, Issue:5

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular Diseases; Disease Models

2011
Local anesthetic systemic toxicity: update on mechanisms and treatment.
    Current opinion in anaesthesiology, 2011, Volume: 24, Issue:5

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular Diseases; Disease Models

2011
Local anesthetic systemic toxicity: update on mechanisms and treatment.
    Current opinion in anaesthesiology, 2011, Volume: 24, Issue:5

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular Diseases; Disease Models

2011
Local anesthetic systemic toxicity: update on mechanisms and treatment.
    Current opinion in anaesthesiology, 2011, Volume: 24, Issue:5

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular Diseases; Disease Models

2011
Local anesthetic systemic toxicity: update on mechanisms and treatment.
    Current opinion in anaesthesiology, 2011, Volume: 24, Issue:5

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular Diseases; Disease Models

2011
Local anesthetic systemic toxicity: update on mechanisms and treatment.
    Current opinion in anaesthesiology, 2011, Volume: 24, Issue:5

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular Diseases; Disease Models

2011
Local anesthetic systemic toxicity: update on mechanisms and treatment.
    Current opinion in anaesthesiology, 2011, Volume: 24, Issue:5

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular Diseases; Disease Models

2011
Local anesthetic systemic toxicity: update on mechanisms and treatment.
    Current opinion in anaesthesiology, 2011, Volume: 24, Issue:5

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular Diseases; Disease Models

2011
Local anesthetic systemic toxicity: update on mechanisms and treatment.
    Current opinion in anaesthesiology, 2011, Volume: 24, Issue:5

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular Diseases; Disease Models

2011
Local anesthetic systemic toxicity: update on mechanisms and treatment.
    Current opinion in anaesthesiology, 2011, Volume: 24, Issue:5

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular Diseases; Disease Models

2011
Local anesthetic systemic toxicity: update on mechanisms and treatment.
    Current opinion in anaesthesiology, 2011, Volume: 24, Issue:5

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular Diseases; Disease Models

2011
Local anesthetic systemic toxicity: update on mechanisms and treatment.
    Current opinion in anaesthesiology, 2011, Volume: 24, Issue:5

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular Diseases; Disease Models

2011
Local anesthetic systemic toxicity: update on mechanisms and treatment.
    Current opinion in anaesthesiology, 2011, Volume: 24, Issue:5

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular Diseases; Disease Models

2011
Local anesthetic systemic toxicity: update on mechanisms and treatment.
    Current opinion in anaesthesiology, 2011, Volume: 24, Issue:5

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular Diseases; Disease Models

2011
Local anesthetic systemic toxicity: update on mechanisms and treatment.
    Current opinion in anaesthesiology, 2011, Volume: 24, Issue:5

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular Diseases; Disease Models

2011
Local anesthetic systemic toxicity: update on mechanisms and treatment.
    Current opinion in anaesthesiology, 2011, Volume: 24, Issue:5

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular Diseases; Disease Models

2011
Local anesthetic systemic toxicity: update on mechanisms and treatment.
    Current opinion in anaesthesiology, 2011, Volume: 24, Issue:5

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular Diseases; Disease Models

2011
Local anesthetic systemic toxicity: update on mechanisms and treatment.
    Current opinion in anaesthesiology, 2011, Volume: 24, Issue:5

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular Diseases; Disease Models

2011
Local anesthetic systemic toxicity: update on mechanisms and treatment.
    Current opinion in anaesthesiology, 2011, Volume: 24, Issue:5

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular Diseases; Disease Models

2011
Local anesthetic systemic toxicity: update on mechanisms and treatment.
    Current opinion in anaesthesiology, 2011, Volume: 24, Issue:5

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular Diseases; Disease Models

2011
Local anesthetic systemic toxicity: update on mechanisms and treatment.
    Current opinion in anaesthesiology, 2011, Volume: 24, Issue:5

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular Diseases; Disease Models

2011
Local anesthetic systemic toxicity: update on mechanisms and treatment.
    Current opinion in anaesthesiology, 2011, Volume: 24, Issue:5

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular Diseases; Disease Models

2011
Local anesthetic systemic toxicity: update on mechanisms and treatment.
    Current opinion in anaesthesiology, 2011, Volume: 24, Issue:5

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular Diseases; Disease Models

2011
Local anesthetic systemic toxicity: update on mechanisms and treatment.
    Current opinion in anaesthesiology, 2011, Volume: 24, Issue:5

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular Diseases; Disease Models

2011
Local anesthetic systemic toxicity: update on mechanisms and treatment.
    Current opinion in anaesthesiology, 2011, Volume: 24, Issue:5

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular Diseases; Disease Models

2011
Local anesthetic systemic toxicity: update on mechanisms and treatment.
    Current opinion in anaesthesiology, 2011, Volume: 24, Issue:5

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular Diseases; Disease Models

2011
Local anesthetic systemic toxicity: update on mechanisms and treatment.
    Current opinion in anaesthesiology, 2011, Volume: 24, Issue:5

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular Diseases; Disease Models

2011
Local anesthetic systemic toxicity: update on mechanisms and treatment.
    Current opinion in anaesthesiology, 2011, Volume: 24, Issue:5

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular Diseases; Disease Models

2011
Local anesthetic systemic toxicity: update on mechanisms and treatment.
    Current opinion in anaesthesiology, 2011, Volume: 24, Issue:5

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular Diseases; Disease Models

2011
Local anesthetic systemic toxicity: update on mechanisms and treatment.
    Current opinion in anaesthesiology, 2011, Volume: 24, Issue:5

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular Diseases; Disease Models

2011
Local anesthetic systemic toxicity: update on mechanisms and treatment.
    Current opinion in anaesthesiology, 2011, Volume: 24, Issue:5

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular Diseases; Disease Models

2011
Local anesthetic systemic toxicity: update on mechanisms and treatment.
    Current opinion in anaesthesiology, 2011, Volume: 24, Issue:5

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular Diseases; Disease Models

2011
Local anesthetic systemic toxicity: update on mechanisms and treatment.
    Current opinion in anaesthesiology, 2011, Volume: 24, Issue:5

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular Diseases; Disease Models

2011
Local anesthetic systemic toxicity: update on mechanisms and treatment.
    Current opinion in anaesthesiology, 2011, Volume: 24, Issue:5

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular Diseases; Disease Models

2011
Local anesthetic systemic toxicity: update on mechanisms and treatment.
    Current opinion in anaesthesiology, 2011, Volume: 24, Issue:5

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular Diseases; Disease Models

2011
Safe usage of lidocaine for liposuction.
    Plastic surgical nursing : official journal of the American Society of Plastic and Reconstructive Surgical Nurses, 2003,Fall, Volume: 23, Issue:3

    Topics: Anesthetics, Local; Cardiovascular Diseases; Drug Interactions; Humans; Infusions, Parenteral; Lidoc

2003
Task force IV: pharmacologic interventions. Emergency cardiac care.
    The American journal of cardiology, 1982, Volume: 50, Issue:2

    Topics: Adrenergic beta-Antagonists; Analgesics, Opioid; Anti-Arrhythmia Agents; Atropine; Calcium Channel B

1982
Recent advances in local anaesthesia.
    Canadian Anaesthetists' Society journal, 1986, Volume: 33, Issue:3 Pt 2

    Topics: Acidosis; Anesthesia, Local; Anesthetics, Local; Animals; Arrhythmias, Cardiac; Bupivacaine; Cardiov

1986
Clinical pharmacology of drug interactions.
    Annual review of medicine, 1973, Volume: 24

    Topics: Antihypertensive Agents; Blood Coagulation Disorders; Cardiovascular Diseases; Coumarins; Drug Inter

1973
Alteration in pharmacologic response induced by cardiovascular disease.
    Cardiovascular clinics, 1974, Volume: 6, Issue:2

    Topics: Cardiac Output; Cardiovascular Diseases; Coronary Vessels; Digitalis Glycosides; Half-Life; Heart; H

1974

Trials

4 trials available for lidocaine and Cardiovascular Diseases

ArticleYear
Intra-articular administration of lidocaine in anaesthetized dogs: pharmacokinetic profile and safety on cardiovascular and nervous systems.
    Journal of veterinary pharmacology and therapeutics, 2015, Volume: 38, Issue:4

    Topics: Anesthesia, General; Anesthetics, Local; Animals; Area Under Curve; Cardiovascular Diseases; Central

2015
Effect of local anesthesia and intravenous sedation on pain perception and vasovagal reactions during femoral arterial sheath removal after percutaneous coronary intervention.
    International journal of cardiology, 2007, Apr-04, Volume: 116, Issue:3

    Topics: Aged; Anesthetics, Local; Angioplasty, Balloon, Coronary; Bradycardia; Cardiovascular Diseases; Cons

2007
Effect of nebulized lignocaine on airway irritation and haemodynamic changes during induction of anaesthesia with desflurane.
    British journal of anaesthesia, 1995, Volume: 75, Issue:5

    Topics: Adult; Anesthesia, Local; Anesthetics, Inhalation; Anesthetics, Local; Cardiovascular Diseases; Desf

1995
Prophylactic lidocaine in the early phase of suspected myocardial infarction.
    American heart journal, 1985, Volume: 110, Issue:2

    Topics: Adult; Aged; Arrhythmias, Cardiac; Brain Diseases; Cardiovascular Diseases; Clinical Trials as Topic

1985

Other Studies

20 other studies available for lidocaine and Cardiovascular Diseases

ArticleYear
Three-Dimensional Cardiomyocyte-Nanobiosensing System for Specific Recognition of Drug Subgroups.
    ACS sensors, 2023, 06-23, Volume: 8, Issue:6

    Topics: Cardiovascular Diseases; Electroporation; Humans; Lidocaine; Myocytes, Cardiac

2023
Pharmacokinetics and clinical efficacy of lidocaine in cattle after intranasal administration during rhinotracheobronchoscopy.
    Journal of veterinary pharmacology and therapeutics, 2009, Volume: 32, Issue:3

    Topics: Administration, Intranasal; Anesthetics, Local; Animals; Bronchoscopy; Cardiovascular Diseases; Catt

2009
Membrane polarity: a target for myocardial protection and reduced inflammation in adult and pediatric cardiothoracic surgery.
    The Journal of thoracic and cardiovascular surgery, 2010, Volume: 140, Issue:6

    Topics: Adenosine; Adult; Anti-Arrhythmia Agents; Cardiac Surgical Procedures; Cardioplegic Solutions; Cardi

2010
Why change?
    The Journal of thoracic and cardiovascular surgery, 2010, Volume: 140, Issue:6

    Topics: Adenosine; Adult; Anti-Arrhythmia Agents; Cardiac Surgical Procedures; Cardioplegic Solutions; Cardi

2010
After the hype, HOPE (and HPS): some lessons from the Women's Health Initiative trial, the Heart Outcomes Prevention Evaluation study and the Heart Prevention Study.
    Sao Paulo medical journal = Revista paulista de medicina, 2003, Jan-02, Volume: 121, Issue:1

    Topics: Anti-Arrhythmia Agents; Arteriosclerosis; Cardiovascular Diseases; Causality; Clinical Trials as Top

2003
[PERIARTHRITIS OF THE SHOULDER AND CARDIOVASCULAR DISEASES].
    Coeur et medecine interne, 1963, Volume: 58

    Topics: Adrenal Cortex Hormones; Cardiovascular Diseases; Coronary Disease; Diagnosis; Humans; Lidocaine; My

1963
Cardiac drug overdose.
    American family physician, 1982, Volume: 25, Issue:1

    Topics: Arrhythmias, Cardiac; Bretylium Compounds; Cardiovascular Agents; Cardiovascular Diseases; Digoxin;

1982
Drug carriers in cardiovascular pharmacology.
    Advances in cardiology, 1980, Volume: 27

    Topics: Animals; Cardiovascular Diseases; Carrier Proteins; Dogs; Gangliosides; Humans; Lidocaine; Liposomes

1980
Antiarrhythmic classifications in the 2000 Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.
    Circulation, 2001, Jul-31, Volume: 104, Issue:5

    Topics: Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Cardiovascular Diseases; Humans; Lidocaine; P

2001
CIBIS, MERIT-HF, and COPERNICUS trial outcomes: do they complete the chapter on beta-adrenergic blockers as antiarrhythmic and antifibrillatory drugs?
    Journal of cardiovascular pharmacology and therapeutics, 2001, Volume: 6, Issue:2

    Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Cardiovascular Diseases; Clinical Trials as Top

2001
Cardiovascular response to epinephrine-containing local anesthesia in patients with cardiovascular disease.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2001, Volume: 92, Issue:6

    Topics: Aged; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Blood Pressure; Cardiac Output; Car

2001
Drugs used in the care of the cardiac patient.
    The Nursing clinics of North America, 1978, Volume: 13, Issue:3

    Topics: Anticoagulants; Antihypertensive Agents; Arrhythmias, Cardiac; Atropine; Bretylium Tosylate; Cardiac

1978
Neonatal and pediatric cardiovascular crises.
    JAMA, 1975, Apr-14, Volume: 232, Issue:2

    Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Bradycardia; Cardiovascular Diseases; Digoxin; Emerge

1975
Marked QRS complex abnormalities and sodium channel blockade by propoxyphene reversed with lidocaine.
    The Journal of clinical investigation, 1989, Volume: 84, Issue:5

    Topics: Adult; Cardiovascular Diseases; Cardiovascular System; Dextropropoxyphene; Electric Conductivity; El

1989
Attenuation of circulatory response to laryngoscopy and tracheal intubation--a comparative study of different low doses of fentanyl with or without additional lidocaine in various regimens.
    Ma zui xue za zhi = Anaesthesiologica Sinica, 1985, Volume: 23, Issue:2

    Topics: Adult; Aged; Anesthesia, Endotracheal; Cardiovascular Diseases; Fentanyl; Humans; Intubation, Intrat

1985
[Cardiocirculatory responses to tracheal intubation in the heart patient].
    Cahiers d'anesthesiologie, 1985, Volume: 33, Issue:2

    Topics: Aerosols; Anesthesia, Endotracheal; Anesthesia, Local; Cardiovascular Diseases; Female; Fentanyl; He

1985
Effects of an unusually large amount of intravenous lidocaine.
    Journal of the South Carolina Medical Association (1975), 1972, Volume: 68, Issue:9

    Topics: Cardiovascular Diseases; Hemodynamics; Humans; Injections, Intravenous; Lidocaine; Male; Middle Aged

1972
Editorial: Vasoconstrictors in local anesthetic.
    Australian dental journal, 1973, Volume: 18, Issue:3

    Topics: Anesthesia, Dental; Anesthesia, Local; Anesthetics; Antidepressive Agents; Cardiovascular Diseases;

1973
Local anaesthetics.
    Laval medical, 1971, Volume: 42, Issue:8

    Topics: Amides; Anesthetics, Local; Brain Edema; Cardiovascular Diseases; Central Nervous System Diseases; C

1971
[Lignocaine is of no value in emergency treatment of stable ventricular tachycardia].
    La Presse medicale, 1969, May-03, Volume: 77, Issue:22

    Topics: Adolescent; Adult; Aged; Cardiovascular Diseases; Electrocardiography; Humans; Injections, Intraveno

1969