Page last updated: 2024-10-28

lidocaine and Cancer of Stomach

lidocaine has been researched along with Cancer of Stomach in 14 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Research Excerpts

ExcerptRelevanceReference
"A 53-year-old man with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) underwent a gastrectomy."7.74Anesthetic management of a patient with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) during laparotomy. ( Fujita, Y; Katsuya, H; Sasano, H; Sasano, N; So, M; Sobue, K, 2007)
"To evaluate whether intraoperative low-dose lidocaine infusion decreases postoperative analgesic consumption, ileus, and duration of hospital stay."5.16Intraoperative intravenous lidocaine reduces hospital length of stay following open gastrectomy for stomach cancer in men. ( Kang, JG; Kim, EH; Kim, MH; Lee, SH, 2012)
"A 53-year-old man with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) underwent a gastrectomy."3.74Anesthetic management of a patient with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) during laparotomy. ( Fujita, Y; Katsuya, H; Sasano, H; Sasano, N; So, M; Sobue, K, 2007)
"Lidocaine is a short-acting local anesthetic, and intravenous lidocaine has been shown to have analgesic efficacy in surgical settings."2.82Efficacy of Intravenous Lidocaine During Endoscopic Submucosal Dissection for Gastric Neoplasm: A Randomized, Double-Blind, Controlled Study. ( Choi, JB; Jeong, HW; Kim, JE; Kim, SY; Koo, BN; Lee, BH, 2016)
"Local lidocaine injections into the submucosal layer were safe when administered during ESDs performed on EGC patients under sedation."2.74Pilot study to assess the safety of local lidocaine injections during endoscopic submucosal dissection for early gastric cancer. ( Gotoda, T; Ikehara, H; Kiriyama, S; Mashimo, Y; Nishimoto, F; Oda, I, 2009)
"Lidocaine has been manifested to exert anti-tumor role in gastric cancer (GC) progression."1.72Lidocaine Suppresses Gastric Cancer Development Through Circ_ANO5/miR-21-5p/LIFR Axis. ( Guan, E; Liu, H; Xu, N, 2022)
"Lidocaine is a well-documented local anesthetic that has been reported to suppress cancer development."1.51Lidocaine inhibits growth, migration and invasion of gastric carcinoma cells by up-regulation of miR-145. ( Li, Z; Lou, A; Sui, H; Yang, J, 2019)
"4, Ref."1.51Anti-tumor effects of lidocaine on human gastric cancer cells in vitro. ( Chen, YJ; Liu, Q; Ye, L; Zhang, Y, 2019)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19902 (14.29)18.7374
1990's0 (0.00)18.2507
2000's3 (21.43)29.6817
2010's7 (50.00)24.3611
2020's2 (14.29)2.80

Authors

AuthorsStudies
Zhang, X1
Gu, G1
Li, X1
Zhang, C1
Guan, E1
Liu, H1
Xu, N1
Yang, W1
Cai, J1
Zhang, H1
Wang, G1
Jiang, W1
Sui, H1
Lou, A1
Li, Z1
Yang, J1
Ye, L1
Zhang, Y1
Chen, YJ1
Liu, Q1
Yon, JH1
Choi, GJ1
Kang, H1
Park, JM1
Yang, HS1
Kim, JE1
Choi, JB1
Koo, BN1
Jeong, HW1
Lee, BH1
Kim, SY1
Kiriyama, S1
Oda, I1
Nishimoto, F1
Mashimo, Y1
Ikehara, H1
Gotoda, T1
Kaneishi, K1
Kawabata, M1
Kang, JG1
Kim, MH1
Kim, EH1
Lee, SH1
Mercadante, S1
Villari, P1
Ferrera, P1
Arcuri, E1
Sasano, N1
Fujita, Y1
So, M1
Sobue, K1
Sasano, H1
Katsuya, H1
Miyabe, M1
Mayumi, T1
Horikawa, D1
Motohara, T1
Itoh, N1
Hayashi, H1
Aoki, H1
Kubota, H1
Murakami, T1
Dohi, S1
Ogino, R1
Yamashita, M1
Matsuki, A1
Oyama, T1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Intravenous Lidocaine for Postoperative Recovery in Liver Surgery, a Randomized Double Blinded Placebo-controlled Study[NCT05153785]Phase 2/Phase 380 participants (Anticipated)Interventional2021-11-15Recruiting
[NCT01961752]111 participants (Actual)Interventional2012-07-31Completed
[NCT02037399]50 participants (Anticipated)Interventional2013-07-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

4 trials available for lidocaine and Cancer of Stomach

ArticleYear
Intraoperative systemic lidocaine for pre-emptive analgesics in subtotal gastrectomy: a prospective, randomized, double-blind, placebo-controlled study.
    Canadian journal of surgery. Journal canadien de chirurgie, 2014, Volume: 57, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Opioid; Anest

2014
Efficacy of Intravenous Lidocaine During Endoscopic Submucosal Dissection for Gastric Neoplasm: A Randomized, Double-Blind, Controlled Study.
    Medicine, 2016, Volume: 95, Issue:18

    Topics: Abdominal Pain; Adenocarcinoma; Adenoma; Administration, Intravenous; Aged; Analgesics, Opioid; Anes

2016
Pilot study to assess the safety of local lidocaine injections during endoscopic submucosal dissection for early gastric cancer.
    Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2009, Volume: 12, Issue:3

    Topics: Aged; Anesthetics, Local; Blood Pressure; Electrocardiography; Female; Gastric Mucosa; Gastroscopy;

2009
Pilot study to assess the safety of local lidocaine injections during endoscopic submucosal dissection for early gastric cancer.
    Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2009, Volume: 12, Issue:3

    Topics: Aged; Anesthetics, Local; Blood Pressure; Electrocardiography; Female; Gastric Mucosa; Gastroscopy;

2009
Pilot study to assess the safety of local lidocaine injections during endoscopic submucosal dissection for early gastric cancer.
    Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2009, Volume: 12, Issue:3

    Topics: Aged; Anesthetics, Local; Blood Pressure; Electrocardiography; Female; Gastric Mucosa; Gastroscopy;

2009
Pilot study to assess the safety of local lidocaine injections during endoscopic submucosal dissection for early gastric cancer.
    Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2009, Volume: 12, Issue:3

    Topics: Aged; Anesthetics, Local; Blood Pressure; Electrocardiography; Female; Gastric Mucosa; Gastroscopy;

2009
Intraoperative intravenous lidocaine reduces hospital length of stay following open gastrectomy for stomach cancer in men.
    Journal of clinical anesthesia, 2012, Volume: 24, Issue:6

    Topics: Analgesics, Opioid; Anesthetics, Local; Double-Blind Method; Gastrectomy; Hospitalization; Hospitals

2012

Other Studies

10 other studies available for lidocaine and Cancer of Stomach

ArticleYear
Lidocaine alleviates cisplatin resistance and inhibits migration of MGC-803/DDP cells through decreasing miR-10b.
    Cell cycle (Georgetown, Tex.), 2020, Volume: 19, Issue:19

    Topics: Antineoplastic Agents; Apoptosis; beta Catenin; Cell Line, Tumor; Cell Movement; Cisplatin; Down-Reg

2020
Lidocaine Suppresses Gastric Cancer Development Through Circ_ANO5/miR-21-5p/LIFR Axis.
    Digestive diseases and sciences, 2022, Volume: 67, Issue:6

    Topics: Anoctamins; Cell Proliferation; Humans; Leukemia Inhibitory Factor Receptor alpha Subunit; Lidocaine

2022
Effects of Lidocaine and Ropivacaine on Gastric Cancer Cells Through Down-regulation of ERK1/2 Phosphorylation
    Anticancer research, 2018, Volume: 38, Issue:12

    Topics: Anesthetics, Local; Cell Line, Tumor; Down-Regulation; Humans; Lidocaine; MAP Kinase Signaling Syste

2018
Lidocaine inhibits growth, migration and invasion of gastric carcinoma cells by up-regulation of miR-145.
    BMC cancer, 2019, Mar-15, Volume: 19, Issue:1

    Topics: Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Gene Expression Regulation, Neop

2019
Anti-tumor effects of lidocaine on human gastric cancer cells in vitro.
    Bratislavske lekarske listy, 2019, Volume: 120, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Humans; Lidocaine; Stomach N

2019
Continuous subcutaneous infusion of lidocaine for persistent hiccup in advanced cancer.
    Palliative medicine, 2013, Volume: 27, Issue:3

    Topics: Aged, 80 and over; Anesthetics, Local; Hiccup; Humans; Infusions, Subcutaneous; Lidocaine; Male; Sto

2013
Local anesthetic switching for intrathecal tachyphylaxis in cancer patients with pain.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:1

    Topics: Adult; Anesthetics, Local; Bupivacaine; Carcinoma, Small Cell; Endometrial Neoplasms; Female; Humans

2003
Anesthetic management of a patient with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) during laparotomy.
    Journal of anesthesia, 2007, Volume: 21, Issue:1

    Topics: Amides; Anesthesia; Anesthesia, Epidural; Anesthetics, Intravenous; Anesthetics, Local; Blood Gas An

2007
[Anesthetic managements for major surgery in a patient with myocardial revascularization].
    Masui. The Japanese journal of anesthesiology, 1983, Volume: 32, Issue:1

    Topics: Adenocarcinoma; Anesthesia, Epidural; Coronary Artery Bypass; Gastrectomy; Humans; Lidocaine; Male;

1983
[Anesthetic management of dermatomyositis with malignancy].
    Masui. The Japanese journal of anesthesiology, 1984, Volume: 33, Issue:2

    Topics: Anesthesia, General; Dermatomyositis; Gastrectomy; Humans; Lidocaine; Male; Middle Aged; Pancuronium

1984