Page last updated: 2024-10-28

lidocaine and Cancer-Associated Pain

lidocaine has been researched along with Cancer-Associated Pain in 17 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Research Excerpts

ExcerptRelevanceReference
"Internationally, use of lidocaine infusions to treat cancer pain varies by center."9.01Lidocaine for Cancer Pain in Adults: A Systematic Review and Meta-Analysis. ( Agar, M; Lee, JT; Sanderson, CR; Xuan, W, 2019)
"This retrospective review assesses the safety and efficacy of subcutaneous lidocaine infusions for complex cancer pain, in a specialist palliative care unit."8.02Subcutaneous Lidocaine Infusion for Complex Cancer Pain: A Retrospective Review. ( Al Ruheili, J; Barham, D; Clark, H; Ferguson, L, 2021)
" This is a retrospective case series of 10 cancer patients across four institutions, with attention to dosing of both agents, and subsequent decrease in morphine-equivalent daily dosing (MEDD)."5.56A Multi-Centered Case Series Highlighting the Clinical Use and Dosing of Lidocaine and Mexiletine for Refractory Cancer Pain. ( Atayee, RS; Edmonds, KP; Geiger-Hayes, J; Hausdorff, J; Naidu, D; Saphire, ML, 2020)
"Lidocaine infusion was administered for a period of 45 days with targeted lidocaine blood levels not exceeding 5 mcg/mL."5.51Intravenous Lidocaine Administered as Twice Daily Bolus and Continuous Infusion for Intractable Cancer Pain and Wound Care Pain. ( Kintzel, PE; Knol, JD; Roe, G, 2019)
"Internationally, use of lidocaine infusions to treat cancer pain varies by center."5.01Lidocaine for Cancer Pain in Adults: A Systematic Review and Meta-Analysis. ( Agar, M; Lee, JT; Sanderson, CR; Xuan, W, 2019)
"This retrospective review assesses the safety and efficacy of subcutaneous lidocaine infusions for complex cancer pain, in a specialist palliative care unit."4.02Subcutaneous Lidocaine Infusion for Complex Cancer Pain: A Retrospective Review. ( Al Ruheili, J; Barham, D; Clark, H; Ferguson, L, 2021)
"Chronic postsurgical pain (CPSP) is an important and well recognized cause of much long-term suffering, which in some cases may be preventable and affects many people living with cancer."2.58Chronic postsurgical pain and cancer: the catch of surviving the unsurvivable. ( Bhaskar, A; Humble, SR; Jayaweera, A; Varela, N, 2018)
"The use of topiceuticals in localized neuropathic pain associated with malignancy remain a valuable option with many advantages over systemic treatments."2.55The role of topiceuticals in cancer pain. ( Paisley, P; Serpell, M, 2017)
" This is a retrospective case series of 10 cancer patients across four institutions, with attention to dosing of both agents, and subsequent decrease in morphine-equivalent daily dosing (MEDD)."1.56A Multi-Centered Case Series Highlighting the Clinical Use and Dosing of Lidocaine and Mexiletine for Refractory Cancer Pain. ( Atayee, RS; Edmonds, KP; Geiger-Hayes, J; Hausdorff, J; Naidu, D; Saphire, ML, 2020)
"Lidocaine infusion was administered for a period of 45 days with targeted lidocaine blood levels not exceeding 5 mcg/mL."1.51Intravenous Lidocaine Administered as Twice Daily Bolus and Continuous Infusion for Intractable Cancer Pain and Wound Care Pain. ( Kintzel, PE; Knol, JD; Roe, G, 2019)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's13 (76.47)24.3611
2020's4 (23.53)2.80

Authors

AuthorsStudies
Lee, J1
Currow, D1
Lovell, M1
Phillips, JL1
McLachlan, A1
Ritchie, M1
Brown, L1
Fazekas, B1
Aggarwal, R1
Seah, D1
Sheehan, C1
Chye, R1
Noble, B1
McCaffrey, N1
Aggarwal, G1
George, R1
Kow, M1
Ayoub, C1
Linton, A1
Sanderson, C1
Mittal, D1
Rao, A1
Prael, G1
Urban, K1
Vandersman, P1
Agar, M2
Atayee, RS2
Naidu, D1
Geiger-Hayes, J1
Saphire, ML1
Hausdorff, J1
Edmonds, KP2
Chong, PH1
Yeo, ZZ1
Ferguson, L1
Al Ruheili, J1
Clark, H1
Barham, D1
Paisley, P1
Serpell, M1
Remeniuk, B1
King, T1
Sukhtankar, D1
Nippert, A1
Li, N1
Li, F1
Cheng, K1
Rice, KC1
Porreca, F1
Humble, SR1
Varela, N1
Jayaweera, A1
Bhaskar, A1
Ali, SK1
Abdulkarim, S1
Hakim, RC1
Liu, CW1
Flamer, D1
Kintzel, PE1
Knol, JD1
Roe, G1
Viderman, D1
Nurpeissov, A1
Bilotta, F1
Lee, JT1
Sanderson, CR1
Xuan, W1
Huang, R1
Jiang, L1
Cao, Y1
Liu, H1
Ping, M1
Li, W1
Xu, Y1
Ning, J1
Chen, Y1
Wang, X1
Hasuo, H1
Sakuma, H1
Uchitani, K1
Ohue, K1
Fukunaga, M1
Woolley, CA1
Oswald, J1
Chen, J1
Tagami, K1
Miura, T1
Suzuki, M1
Matoba, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of The Effects Of General Anesthesia and PECS Block Methods on Blood Leukocyte, Neutrophil, Lymphocyte, and Platelet Counts in Patients With Breast Cancer[NCT06151639]26 participants (Actual)Observational2022-08-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for lidocaine and Cancer-Associated Pain

ArticleYear
Parenteral Lidocaine for Complex Cancer Pain in the Home or Inpatient Hospice Setting: A Review and Synthesis of the Evidence.
    Journal of palliative medicine, 2021, Volume: 24, Issue:8

    Topics: Anesthetics, Local; Cancer Pain; Hospices; Humans; Inpatients; Lidocaine; Neoplasms; Retrospective S

2021
The role of topiceuticals in cancer pain.
    Current opinion in supportive and palliative care, 2017, Volume: 11, Issue:2

    Topics: Administration, Cutaneous; Analgesics, Opioid; Anesthetics, Local; Cancer Pain; Capsaicin; Clinical

2017
Chronic postsurgical pain and cancer: the catch of surviving the unsurvivable.
    Current opinion in supportive and palliative care, 2018, Volume: 12, Issue:2

    Topics: Analgesics; Analgesics, Opioid; Cancer Pain; Chronic Pain; Drug Therapy, Combination; Gabapentin; Ge

2018
Lidocaine for Cancer Pain in Adults: A Systematic Review and Meta-Analysis.
    Journal of palliative medicine, 2019, Volume: 22, Issue:3

    Topics: Adult; Anesthetics, Local; Cancer Pain; Humans; Lidocaine; Sodium Channel Blockers

2019
Comparative Efficacy of Therapeutics for Chronic Cancer Pain: A Bayesian Network Meta-Analysis.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2019, 07-10, Volume: 37, Issue:20

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bayes Theorem; Bridged Bicyclo Compou

2019

Trials

2 trials available for lidocaine and Cancer-Associated Pain

ArticleYear
Lidocaine for Neuropathic Cancer Pain (LiCPain): study protocol for a mixed-methods pilot study.
    BMJ open, 2023, 02-21, Volume: 13, Issue:2

    Topics: Cancer Pain; Clinical Trials, Phase II as Topic; Humans; Lidocaine; Neoplasms; Neuralgia; Pilot Proj

2023
Short-Term Effects of 10% Lidocaine Ointment on Allodynia in Cancer Pain: A Randomized, Double-Blind, Placebo-Controlled Crossover Study.
    Journal of palliative medicine, 2019, Volume: 22, Issue:11

    Topics: Aged; Cancer Pain; Cross-Over Studies; Double-Blind Method; Female; Humans; Hyperalgesia; Lidocaine;

2019

Other Studies

10 other studies available for lidocaine and Cancer-Associated Pain

ArticleYear
A Multi-Centered Case Series Highlighting the Clinical Use and Dosing of Lidocaine and Mexiletine for Refractory Cancer Pain.
    Journal of pain & palliative care pharmacotherapy, 2020, Volume: 34, Issue:2

    Topics: Administration, Oral; Adult; Aged; Anesthetics, Local; Cancer Pain; Female; Humans; Infusions, Intra

2020
Subcutaneous Lidocaine Infusion for Complex Cancer Pain: A Retrospective Review.
    Journal of pain & palliative care pharmacotherapy, 2021, Volume: 35, Issue:3

    Topics: Analgesics, Opioid; Anesthetics, Local; Cancer Pain; Humans; Infusions, Intravenous; Lidocaine; Neop

2021
Disease modifying actions of interleukin-6 blockade in a rat model of bone cancer pain.
    Pain, 2018, Volume: 159, Issue:4

    Topics: Adenocarcinoma; Analgesics; Analysis of Variance; Anesthetics, Local; Animals; Bone Neoplasms; Bufan

2018
Treatment of Anal Cancer Pain-A Case Report.
    Journal of pain and symptom management, 2018, Volume: 56, Issue:1

    Topics: Adult; Anesthetics, Local; Anus Neoplasms; Cancer Pain; Carcinoma, Squamous Cell; Humans; Hydrocorti

2018
Case Report: Utility of Ketamine, Lidocaine, and Mexiletine as Nonopioid Adjuvants in Complex Cancer-Associated Pain.
    Journal of pain & palliative care pharmacotherapy, 2018, Volume: 32, Issue:1

    Topics: Adult; Analgesics; Analgesics, Opioid; Anesthetics, Local; Cancer Pain; Carcinoma, Squamous Cell; Fe

2018
Supraclavicular Brachial Plexus Neurolysis for a Malignant Peripheral Nerve Sheath Tumor: A Case Report.
    A&A practice, 2018, Dec-01, Volume: 11, Issue:11

    Topics: Alcohols; Brachial Plexus; Bupivacaine; Cancer Pain; Female; Humans; Lidocaine; Middle Aged; Nerve B

2018
Intravenous Lidocaine Administered as Twice Daily Bolus and Continuous Infusion for Intractable Cancer Pain and Wound Care Pain.
    Journal of palliative medicine, 2019, Volume: 22, Issue:3

    Topics: Adult; Anesthetics, Local; Bandages; Buttocks; Cancer Pain; Carcinoma, Squamous Cell; Humans; Infusi

2019
Intravenous lidocaine in the management of severe brain tumor-associated headache.
    Journal of clinical anesthesia, 2019, Volume: 55

    Topics: Adolescent; Anesthetics, Local; Brain Neoplasms; Cancer Pain; Female; Headache; Humans; Infusions, I

2019
Painful Inguinal Angiomyomatous Hamartoma Responsive to Conservative Pain Management: A Case Report.
    A&A practice, 2019, Nov-15, Volume: 13, Issue:10

    Topics: Angiomyoma; Bupivacaine; Cancer Pain; Conservative Treatment; Drug Therapy, Combination; Epinephrine

2019
Analgesic Effectiveness of Systemic Lidocaine Administration for Abdominal Cancer Pain Caused by Peritoneal Carcinomatosis: A Case Series of 10 Patients.
    Journal of palliative medicine, 2016, Volume: 19, Issue:12

    Topics: Abdominal Pain; Analgesics; Cancer Pain; Humans; Lidocaine; Peritoneal Neoplasms

2016
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