Page last updated: 2024-10-28

lidocaine and Brugada ECG Pattern

lidocaine has been researched along with Brugada ECG Pattern in 45 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Research Excerpts

ExcerptRelevanceReference
"We demonstrate that lidocaine may suppress Brugada syndrome associated with the N406S mutation by preventing the sodium channel from accumulating in the intermediate inactivation state."7.74A paradoxical effect of lidocaine for the N406S mutation of SCN5A associated with Brugada syndrome. ( Ashihara, T; Horie, M; Imoto, K; Ito, M; Itoh, H; Jo, H; Nagaoka, I; Nakazawa, Y; Oka, Y; Sakaguchi, T; Tsuji, K; Yao, T, 2007)
"Pilsicainide induced VA in some patients with Brugada syndrome, but this result may not be used as a parameter of the risk stratification of Brugada syndrome."7.74Incidence and initial characteristics of pilsicainide-induced ventricular arrhythmias in patients with Brugada syndrome. ( Aizawa, Y; Chinushi, M; Furushima, H; Izumi, D; Komura, S; Tanabe, Y; Washizuka, T, 2007)
"Brugada syndrome has been linked to mutations in SCN5A."5.35Lidocaine-induced Brugada syndrome phenotype linked to a novel double mutation in the cardiac sodium channel. ( Antzelevitch, C; Barajas-Martínez, HM; Brugada, R; Cordeiro, JM; Dumaine, R; Elena, B; Hu, D; Kovacs, RJ; Kui, H; Meltser, H; Wu, Y, 2008)
" We investigated the association between spontaneous ventricular fibrillation (VF) occurrence and TWA after pilsicainide, a sodium channel blocker administration in BS patients."5.13Clinical significance of macroscopic T-wave alternans after sodium channel blocker administration in patients with Brugada syndrome. ( Banba, K; Kusano, KF; Miura, D; Morita, H; Nagase, S; Nakamura, K; Nishii, N; Ohe, T; Tada, T; Watanabe, A, 2008)
"We administered intravenous pilsicainide to 245 consecutive patients with Brugada syndrome (181 patients with spontaneous type 1 ECG, 64 patients with non-type 1 ECG)."3.88Prognostic Significance of the Sodium Channel Blocker Test in Patients With Brugada Syndrome. ( Ito, H; Kawada, S; Miyamoto, M; Morimoto, Y; Morita, H; Nakagawa, K; Nishii, N; Tachibana, M; Ueoka, A; Watanabe, A, 2018)
"Administration of pilsicainide, a class IC antiarrhythmic agent, caused Brugada- type ST elevation in a 66-year-old Japanese male who presented with paroxysmal atrial fibrillation (PAF), type I atrial flutter and inducible ventricular fibrillation (VF) during electrophysiological study."3.83A Novel SCN5A Mutation Associated with Drug Induced Brugada Type ECG. ( Ai, T; Horie, M; Itoh, H; Makiyama, T; Shimizu, A; Turker, I; Ueyama, T; Vatta, M, 2016)
"We demonstrate that lidocaine may suppress Brugada syndrome associated with the N406S mutation by preventing the sodium channel from accumulating in the intermediate inactivation state."3.74A paradoxical effect of lidocaine for the N406S mutation of SCN5A associated with Brugada syndrome. ( Ashihara, T; Horie, M; Imoto, K; Ito, M; Itoh, H; Jo, H; Nagaoka, I; Nakazawa, Y; Oka, Y; Sakaguchi, T; Tsuji, K; Yao, T, 2007)
"Pilsicainide induced VA in some patients with Brugada syndrome, but this result may not be used as a parameter of the risk stratification of Brugada syndrome."3.74Incidence and initial characteristics of pilsicainide-induced ventricular arrhythmias in patients with Brugada syndrome. ( Aizawa, Y; Chinushi, M; Furushima, H; Izumi, D; Komura, S; Tanabe, Y; Washizuka, T, 2007)
" Routine use of intravenous sodium bicarbonate is recommended to combat the severe metabolic acidosis accompanying cardiac arrest."3.64THE CHEMOTHERAPY OF CARDIAC ARREST. ( MINUCK, M, 1965)
" We hypothesized that the use of local dental anesthesia with lidocaine with and without epinephrine is safe and does not result in life-threatening arrhythmias in patients with channelopathies."2.90Is It Safe for Patients With Cardiac Channelopathies to Undergo Routine Dental Care? Experience From a Single-Center Study. ( Barbosa, SA; Carvalho, CMA; Darrieux, FCC; Grupi, CJ; Hachul, DT; Montano, TCP; Neves, ILI; Neves, RS; Oliveira, ACG; Olivetti, NQS; Pastore, CA; Sacilotto, L; Samesima, N; Santos-Paul, MAD; Scanavacca, MI; Wu, TC, 2019)
"Brugada syndrome has been linked to mutations in SCN5A."1.35Lidocaine-induced Brugada syndrome phenotype linked to a novel double mutation in the cardiac sodium channel. ( Antzelevitch, C; Barajas-Martínez, HM; Brugada, R; Cordeiro, JM; Dumaine, R; Elena, B; Hu, D; Kovacs, RJ; Kui, H; Meltser, H; Wu, Y, 2008)
"Frequent premature ventricular complexes (PVCs) with two different left bundle branch block patterns developed during ST segment elevation."1.35Pilsicainide-induced ST segment elevation and ST segment depression in two patients with variant forms of Brugada-type electrocardiographic abnormalities. ( Aizawa, Y; Chinushi, M; Furushima, H; Izumi, D; Tagawa, M, 2009)

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-19903 (6.67)18.7374
1990's0 (0.00)18.2507
2000's21 (46.67)29.6817
2010's18 (40.00)24.3611
2020's3 (6.67)2.80

Authors

AuthorsStudies
Aleksandrowicz, D1
Hasebe, H1
Yokoya, T1
Murakoshi, N1
Kurebayashi, N1
Loiudice, P1
Monitillo, F1
Nardi, M1
Iacoviello, M1
Casini, G1
Kakihara, J1
Takagi, M3
Hayashi, Y1
Tatsumi, H3
Doi, A3
Yoshiyama, M3
Ueoka, A1
Morita, H5
Watanabe, A3
Morimoto, Y1
Kawada, S1
Tachibana, M1
Miyamoto, M1
Nakagawa, K1
Nishii, N3
Ito, H1
Nagayama, T1
Nagase, S3
Kamakura, T2
Wada, M2
Ishibashi, K2
Inoue, YY1
Miyamoto, K2
Noda, T2
Aiba, T2
Takaki, H2
Sugimachi, M1
Shimizu, W2
Noguchi, T1
Yasuda, S2
Kamakura, S2
Kusano, K2
Oliveira, ACG1
Neves, ILI1
Sacilotto, L1
Olivetti, NQS1
Santos-Paul, MAD1
Montano, TCP1
Carvalho, CMA1
Wu, TC1
Grupi, CJ1
Barbosa, SA1
Pastore, CA1
Samesima, N1
Hachul, DT1
Scanavacca, MI1
Neves, RS1
Darrieux, FCC1
Nakajima, I1
Okamura, H1
Ogawa, H1
Makiyama, T2
Kimura, T1
Yamasaki, H1
Tada, H1
Sekiguchi, Y2
Aonuma, K1
Wang, HG1
Zhu, W1
Kanter, RJ1
Silva, JR1
Honeywell, C1
Gow, RM1
Pitt, GS1
Turker, I1
Vatta, M1
Itoh, H2
Ueyama, T5
Shimizu, A4
Ai, T1
Horie, M2
Barajas-Martínez, HM1
Hu, D1
Cordeiro, JM1
Wu, Y1
Kovacs, RJ1
Meltser, H1
Kui, H1
Elena, B1
Brugada, R1
Antzelevitch, C1
Dumaine, R1
Fozzard, HA1
Sánchez Ortega, JL1
González Pérez, P1
Escribano Jiménez, M1
Kofune, M2
Watanabe, I2
Ashino, S2
Ohkubo, K2
Okumura, Y2
Kofune, T1
Nakai, T2
Hirayama, A2
Omichi, C1
Fujimoto, N1
Kawasaki, A1
Kasai, A1
Chinushi, M2
Tagawa, M1
Izumi, D2
Furushima, H2
Aizawa, Y2
Shimeno, K2
Maeda, K2
Nakagawa, E1
Mizobuchi, M1
Enjoji, Y1
Nakamura, S1
Muranishi, H1
Utsunomiya, M1
Funatsu, A1
Kobayashi, T1
Ogawa, R1
Kishi, R2
Takagi, A2
Sakaue, I1
Takahashi, H1
Matsumoto, N1
Masuhara, K1
Nakazawa, K2
Kobayashi, S1
Miyake, F2
Echizen, H1
Zipes, DP2
Morita, ST2
Wu, J2
Sugi, N3
Yoshiga, Y3
Doi, M1
Ohmiya, T1
Ohno, M1
Yoshida, M1
Matsuzaki, M4
Hisada, T1
Miyagawa, T1
Yakushiji, T1
Tsujimoto, T1
Sakai, M1
Adachi, T1
Ikewaki, K1
Ogata, K1
Ohsuzu, F1
Sakurai, Y1
Nagashima, K1
Kunimoto, S1
Kasamaki, Y1
Murata, K1
Tanaka, T1
Nose, Y1
Wada, Y1
Ripley, A1
Castro, J1
Gadsden, J1
VAN DONGEN, K1
MINUCK, M1
NAVARIVERA, A1
VEGAESQUIVEL, E1
LOPEZ, AJ1
Ikeda, T1
Abe, A1
Yusu, S1
Nakamura, K3
Ishiguro, H1
Mera, H1
Yotsukura, M1
Yoshino, H1
Yodogawa, K1
Morita, N1
Kobayashi, Y1
Takayama, H1
Ohara, T1
Katoh, T1
Takano, T1
Yamagata, T1
Esato, M2
Ohmura, M1
Kanemoto, M1
Kametani, R1
Sawa, A2
Suzuki, S2
Deschênes, I1
Laurita, KR1
Sakurai, T1
Osada, K1
Ryu, S1
Fujita, S1
Matsuda, H1
Ishikawa, Y1
Tsuji, K1
Sakaguchi, T1
Nagaoka, I1
Oka, Y1
Nakazawa, Y1
Yao, T1
Jo, H1
Ashihara, T1
Ito, M1
Imoto, K1
Komura, S1
Tanabe, Y1
Washizuka, T1
Yoshisato, T1
Takeda, H1
Tsuburaya, R1
Endo, N1
Niitsuma, T1
Miura, E1
Hirosaka, A1
Owada, K1
Tamagawa, K1
Clancy, CE1
Wehrens, XH1
Tada, T1
Kusano, KF2
Banba, K2
Miura, D1
Ohe, T2
Kanemori, T1
Shimizu, H1
Oka, K1
Furukawa, Y1
Hiromoto, K1
Mine, T1
Masuyama, T1
Ohyanagi, M1
Madias, JE1
Hiramatsu, S1
Sakuragi, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Safety of Local Dental Anesthesia in Patients With Cardiac Channelopathies[NCT03182777]31 participants (Actual)Interventional2015-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for lidocaine and Brugada ECG Pattern

ArticleYear
[Brugada syndrome, bupivacaine, lidocaine, and techniques to provide local or regional anesthesia: comments on "Ventricular fibrillation in a patient with a type I Brugada syndrome ECG pattern and hypokalemia"].
    Revista espanola de anestesiologia y reanimacion, 2008, Volume: 55, Issue:8

    Topics: Anesthesia, Conduction; Anesthetics, Local; Brugada Syndrome; Bupivacaine; Female; Humans; Hypokalem

2008

Trials

5 trials available for lidocaine and Brugada ECG Pattern

ArticleYear
Is It Safe for Patients With Cardiac Channelopathies to Undergo Routine Dental Care? Experience From a Single-Center Study.
    Journal of the American Heart Association, 2019, 08-06, Volume: 8, Issue:15

    Topics: Adolescent; Adult; Aged; Anesthetics, Local; Brugada Syndrome; Channelopathies; Contraindications, P

2019
Different effect of the pure Na+ channel-blocker pilsicainide on the ST-segment response in the right precordial leads in patients with normal left ventricular function.
    Circulation journal : official journal of the Japanese Circulation Society, 2007, Volume: 71, Issue:1

    Topics: Adult; Aged; Algorithms; Brugada Syndrome; Electrocardiography; Female; Heart Diseases; Humans; Lido

2007
Discrimination of Brugada syndrome patients from individuals with the saddle-back type ST-segment elevation using a marker of the standard 12-lead electrocardiography.
    Circulation journal : official journal of the Japanese Circulation Society, 2007, Volume: 71, Issue:4

    Topics: Adult; Aged; Arrhythmias, Cardiac; Biomarkers; Brugada Syndrome; Diagnosis, Differential; Electrocar

2007
Clinical significance of macroscopic T-wave alternans after sodium channel blocker administration in patients with Brugada syndrome.
    Journal of cardiovascular electrophysiology, 2008, Volume: 19, Issue:1

    Topics: Brugada Syndrome; Electrocardiography; Female; Humans; Lidocaine; Male; Middle Aged; Sodium Channel

2008
Sodium channel blockers enhance the temporal QT interval variability in the right precordial leads in Brugada syndrome.
    Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2008, Volume: 13, Issue:1

    Topics: Brugada Syndrome; Electrocardiography; Electrophysiologic Techniques, Cardiac; Female; Heart Rate; H

2008

Other Studies

39 other studies available for lidocaine and Brugada ECG Pattern

ArticleYear
Amiodarone or lidocaine, that is the question - Pharmacological therapy of refractory ventricular fibrillation associated with Brugada syndrome.
    Resuscitation, 2021, Volume: 169

    Topics: Amiodarone; Anti-Arrhythmia Agents; Brugada Syndrome; Humans; Lidocaine; Ventricular Fibrillation

2021
Pilsicainide Administration Unmasks a Phenotype of Brugada Syndrome in a Patient with Overlap Syndrome due to the E1784K SCN5A Mutation.
    Internal medicine (Tokyo, Japan), 2020, Jan-01, Volume: 59, Issue:1

    Topics: Adult; Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography; Humans; Lidocaine; Long QT Syn

2020
Local peribulbar anesthesia before glaucoma filtering surgery in a patient with Brugada syndrome.
    European journal of ophthalmology, 2021, Volume: 31, Issue:2

    Topics: Aged; Anesthesia, Local; Anesthetics, Local; Blood Pressure; Brugada Syndrome; Electrocardiography;

2021
Utility of 12-lead and signal-averaged Holter electrocardiograms after pilsicainide provocation for risk stratification in Brugada syndrome.
    Heart and vessels, 2017, Volume: 32, Issue:9

    Topics: Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography, Ambulatory; Female; Humans; Lidocaine

2017
Prognostic Significance of the Sodium Channel Blocker Test in Patients With Brugada Syndrome.
    Journal of the American Heart Association, 2018, 05-10, Volume: 7, Issue:10

    Topics: Administration, Intravenous; Adult; Aged; Brugada Syndrome; Death, Sudden, Cardiac; Electrocardiogra

2018
Clinical and Electrocardiographic Differences in Brugada Syndrome With Spontaneous or Drug-Induced Type 1 Electrocardiogram.
    Circulation journal : official journal of the Japanese Circulation Society, 2019, 02-25, Volume: 83, Issue:3

    Topics: Adult; Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography; Female; Humans; Lidocaine; Mal

2019
Significance of electrocardiogram recording in high intercostal spaces in patients with early repolarization syndrome.
    European heart journal, 2016, Feb-14, Volume: 37, Issue:7

    Topics: Adult; Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography; Electrophysiologic Techniques,

2016
Right coronary cusp as a new window of ablation for pilsicainide-induced ventricular premature contractions in a patient with Brugada syndrome.
    Heart and vessels, 2016, Volume: 31, Issue:8

    Topics: Adult; Brugada Syndrome; Electrocardiography; Electrophysiologic Techniques, Cardiac; Heart Ventricl

2016
A novel NaV1.5 voltage sensor mutation associated with severe atrial and ventricular arrhythmias.
    Journal of molecular and cellular cardiology, 2016, Volume: 92

    Topics: Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Heart Conduction System;

2016
A Novel SCN5A Mutation Associated with Drug Induced Brugada Type ECG.
    PloS one, 2016, Volume: 11, Issue:8

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Base Sequence; Brugada Syndrome;

2016
Lidocaine-induced Brugada syndrome phenotype linked to a novel double mutation in the cardiac sodium channel.
    Circulation research, 2008, Aug-15, Volume: 103, Issue:4

    Topics: Anesthetics, Local; Brugada Syndrome; Electrocardiography; Humans; Lidocaine; Male; Middle Aged; Mus

2008
Increased sensitivity to local anesthetic drugs: bedside to bench.
    Circulation research, 2008, Aug-15, Volume: 103, Issue:4

    Topics: Anesthetics, Local; Brugada Syndrome; Electrocardiography; Humans; Lidocaine; Mutation, Missense; So

2008
Action potential alternans in the right ventricular outflow tract in a patient with asymptomatic Brugada syndrome.
    Circulation journal : official journal of the Japanese Circulation Society, 2009, Volume: 73, Issue:3

    Topics: Action Potentials; Aged; Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography; Humans; Lido

2009
Ischemia-induced Brugada-type ST-segment alternans and Brugada syndrome.
    International journal of cardiology, 2010, Oct-29, Volume: 144, Issue:3

    Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Brugada Syndrome; Bundle-Branch Block; Coronary Artery

2010
Pilsicainide-induced ST segment elevation and ST segment depression in two patients with variant forms of Brugada-type electrocardiographic abnormalities.
    Pacing and clinical electrophysiology : PACE, 2009, Volume: 32, Issue:6

    Topics: Adolescent; Adult; Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography; Humans; Injections

2009
A predictor of positive drug provocation testing in individuals with saddle-back type ST-segment elevation.
    Circulation journal : official journal of the Japanese Circulation Society, 2009, Volume: 73, Issue:10

    Topics: Action Potentials; Adult; Brugada Syndrome; Electrocardiography; Female; Humans; Infusions, Intraven

2009
Ventricular late potential in patients with apparently normal electrocardiogram; predictor of Brugada syndrome.
    Pacing and clinical electrophysiology : PACE, 2010, Volume: 33, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Brugada Syndrome; Chi-Square Distribution; Electrocardiography; Fema

2010
Conduction delay in right ventricle as a marker for identifying high-risk patients with Brugada syndrome.
    Journal of cardiovascular electrophysiology, 2010, Jun-01, Volume: 21, Issue:6

    Topics: Adult; Anti-Arrhythmia Agents; Brugada Syndrome; Coronary Sinus; Death, Sudden, Cardiac; Electrocard

2010
A novel microsatellite polymorphism of sodium channel beta1-subunit gene (SCN1B) may underlie abnormal cardiac excitation manifested by coved-type ST-elevation compatible with Brugada syndrome in Japanese.
    International journal of clinical pharmacology and therapeutics, 2010, Volume: 48, Issue:2

    Topics: Adult; Age Factors; Aged; Asian People; Brugada Syndrome; Electrocardiography; Female; Genetic Predi

2010
Genotype-phenotype correlation in tissue models of Brugada syndrome simulating patients with sodium and calcium channelopathies.
    Heart rhythm, 2010, Volume: 7, Issue:6

    Topics: Action Potentials; Adrenergic beta-Agonists; Animals; Anti-Arrhythmia Agents; Body Surface Potential

2010
What variables were associated with the inducibility of ventricular fibrillation during electrophysiologic stimulation test in patients without apparent organic heart disease?
    Journal of cardiology, 2010, Volume: 56, Issue:1

    Topics: Brugada Syndrome; Electric Stimulation; Electrocardiography; Female; Humans; Lidocaine; Male; Middle

2010
Ventricular fibrillation diagnosed during electrophysiological study for non-sustained tachycardia.
    Aviation, space, and environmental medicine, 2010, Volume: 81, Issue:6

    Topics: Adult; Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography; Humans; Japan; Lidocaine; Male

2010
A new criteria differentiating type 2 and 3 Brugada patterns from ordinary incomplete right bundle branch block.
    International heart journal, 2011, Volume: 52, Issue:3

    Topics: Adult; Anti-Arrhythmia Agents; Brugada Syndrome; Bundle-Branch Block; Diagnosis, Differential; Elect

2011
Right ventricular dysfunction in patients with Brugada-like electrocardiography: a two dimensional strain imaging study.
    Cardiovascular ultrasound, 2011, Nov-16, Volume: 9

    Topics: Brugada Syndrome; Echocardiography; Elasticity Imaging Techniques; Electrocardiography; Female; Huma

2011
Local anesthetics, neuraxial anesthesia, and the Brugada syndrome.
    Journal of clinical anesthesia, 2013, Volume: 25, Issue:1

    Topics: Anesthesia, Conduction; Anesthetics, Local; Asthma; Brugada Syndrome; Humans; Intestine, Small; Lido

2013
The action of xylocaine on fibrillation of the heart.
    Archives internationales de pharmacodynamie et de therapie, 1953, Oct-15, Volume: 96, Issue:1

    Topics: Anesthetics; Anesthetics, Local; Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System D

1953
THE CHEMOTHERAPY OF CARDIAC ARREST.
    Canadian Medical Association journal, 1965, Jan-02, Volume: 92

    Topics: Acidosis; Arrhythmias, Cardiac; Bicarbonates; Brugada Syndrome; Cardiac Conduction System Disease; C

1965
[COUNTEREFFECT OF LOCAL BLOCKING AGENTS ON CARDIAC ARRHYTHMIA].
    Zahnarztliche Welt, zahnarztliche Reform, ZWR, 1965, Jan-10, Volume: 66

    Topics: Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Complexes, Premature; Cardiac Conduction System Dise

1965
The full stomach test as a novel diagnostic technique for identifying patients at risk of Brugada syndrome.
    Journal of cardiovascular electrophysiology, 2006, Volume: 17, Issue:6

    Topics: Adult; Brugada Syndrome; Circadian Rhythm; Electrocardiography; Electrophysiologic Techniques, Cardi

2006
High-frequency potentials developed in wavelet-transformed electrocardiogram as a novel indicator for detecting Brugada syndrome.
    Heart rhythm, 2006, Volume: 3, Issue:12

    Topics: Action Potentials; Adrenergic beta-Agonists; Adult; Aged; Anti-Arrhythmia Agents; Brugada Syndrome;

2006
Temperature modulation of ventricular arrhythmogenicity in a canine tissue model of Brugada syndrome.
    Heart rhythm, 2007, Volume: 4, Issue:2

    Topics: Action Potentials; Animals; Body Temperature; Brugada Syndrome; Disease Models, Animal; Dogs; Electr

2007
How can a single mutation cause such arrhythmic havoc?
    Heart rhythm, 2007, Volume: 4, Issue:2

    Topics: Action Potentials; Animals; Body Temperature; Brugada Syndrome; Disease Models, Animal; Dogs; Electr

2007
A paradoxical effect of lidocaine for the N406S mutation of SCN5A associated with Brugada syndrome.
    International journal of cardiology, 2007, Oct-18, Volume: 121, Issue:3

    Topics: Anti-Arrhythmia Agents; Brugada Syndrome; Computer Simulation; Genetic Predisposition to Disease; Hu

2007
Incidence and initial characteristics of pilsicainide-induced ventricular arrhythmias in patients with Brugada syndrome.
    Pacing and clinical electrophysiology : PACE, 2007, Volume: 30, Issue:5

    Topics: Adult; Aged; Arrhythmias, Cardiac; Brugada Syndrome; Electrocardiography; Electrophysiologic Techniq

2007
[Elderly Brugada syndrome with recurrent syncope, diagnosed by pilsicainide challenge test].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2007, Jun-10, Volume: 96, Issue:6

    Topics: Aged; Brugada Syndrome; Electrocardiography; Humans; Lidocaine; Male; Recurrence; Syncope

2007
Mutation-specific effects of lidocaine in Brugada syndrome.
    International journal of cardiology, 2007, Oct-18, Volume: 121, Issue:3

    Topics: Anti-Arrhythmia Agents; Brugada Syndrome; Genetic Predisposition to Disease; Humans; Lidocaine; Musc

2007
Pilsicainide-induced Brugada-type ECG and ventricular arrhythmias originating from the left posterior fascicle in a case with Brugada syndrome associated with idiopathic left ventricular tachycardia.
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2008, Volume: 10, Issue:1

    Topics: Anti-Arrhythmia Agents; Brugada Syndrome; Catheter Ablation; Electrocardiography; Electrophysiologic

2008
Re: Clinical significance of macroscopic T-wave alternans after sodium channel blocker administration in patients with Brugada syndrome.
    Journal of cardiovascular electrophysiology, 2008, Volume: 19, Issue:4

    Topics: Brugada Syndrome; Electrocardiography; Female; Humans; Lidocaine; Male; Middle Aged; Sodium Channel

2008
Longer repolarization in the epicardium at the right ventricular outflow tract causes type 1 electrocardiogram in patients with Brugada syndrome.
    Journal of the American College of Cardiology, 2008, Mar-25, Volume: 51, Issue:12

    Topics: Action Potentials; Adult; Aged; Brugada Syndrome; Case-Control Studies; Electrocardiography; Endocar

2008