lidocaine has been researched along with Bronchial Hyperreactivity in 9 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Bronchial Hyperreactivity: Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory.
| Excerpt | Relevance | Reference |
|---|---|---|
| " placebo in 15 mild asthmatic patients, selected by their response to a histamine challenge (decrease in FEV1 > 20% to less than 18 mg mL-1 of histamine [PC20])." | 9.09 | Lidocaine inhalation for local anaesthesia and attenuation of bronchial hyper-reactivity with least airway irritation. Effect of three different dose regimens. ( Beste, M; Groeben, H; Grosswendt, T; Peters, J; Silvanus, M, 2000) |
| "In volunteers with bronchial hyperreactivity, both lidocaine and salbutamol attenuate the response to an inhalational histamine challenge, and their combined administration has much greater effects than does either drug alone." | 9.08 | Combined intravenous lidocaine and inhaled salbutamol protect against bronchial hyperreactivity more effectively than lidocaine or salbutamol alone. ( Beste, M; Groeben, H; Peters, J; Silvanus, MT, 1998) |
| "It is unclear whether inhaled lidocaine is effective against airway hyperreactivity and inflammation in asthma." | 7.74 | Continued inhalation of lidocaine suppresses antigen-induced airway hyperreactivity and airway inflammation in ovalbumin-sensitized guinea pigs. ( Haraguchi, R; Iwanaga, T; Kubo, H; Muraki, M; Tohda, Y, 2008) |
| "Intravenous lidocaine can attenuate bronchial hyperreactivity." | 5.09 | Both intravenous and inhaled lidocaine attenuate reflex bronchoconstriction but at different plasma concentrations. ( Beste, M; Groeben, H; Peters, J; Silvanus, MT, 1999) |
| "Lidocaine inhalation, in subjects with bronchial hyperreactivity, attenuates evoked bronchoconstriction but also irritates airways." | 5.09 | Combined lidocaine and salbutamol inhalation for airway anesthesia markedly protects against reflex bronchoconstriction. ( Beste, M; Groeben, H; Peters, J; Silvanus, MT, 2000) |
| " placebo in 15 mild asthmatic patients, selected by their response to a histamine challenge (decrease in FEV1 > 20% to less than 18 mg mL-1 of histamine [PC20])." | 5.09 | Lidocaine inhalation for local anaesthesia and attenuation of bronchial hyper-reactivity with least airway irritation. Effect of three different dose regimens. ( Beste, M; Groeben, H; Grosswendt, T; Peters, J; Silvanus, M, 2000) |
| "In volunteers with bronchial hyperreactivity, both lidocaine and salbutamol attenuate the response to an inhalational histamine challenge, and their combined administration has much greater effects than does either drug alone." | 5.08 | Combined intravenous lidocaine and inhaled salbutamol protect against bronchial hyperreactivity more effectively than lidocaine or salbutamol alone. ( Beste, M; Groeben, H; Peters, J; Silvanus, MT, 1998) |
| "It is unclear whether inhaled lidocaine is effective against airway hyperreactivity and inflammation in asthma." | 3.74 | Continued inhalation of lidocaine suppresses antigen-induced airway hyperreactivity and airway inflammation in ovalbumin-sensitized guinea pigs. ( Haraguchi, R; Iwanaga, T; Kubo, H; Muraki, M; Tohda, Y, 2008) |
| "Episodic airway obstruction and reversible bronchial hyperresponsiveness to non-specific irritants are the major symptoms of asthma." | 1.33 | Bronchial epilepsy or broncho-pulmonary hyper-excitability as a model of asthma pathogenesis. ( Graeme Shaw, D; Hoang, BX; Hoang, C; Levine, SA; Pham, P, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Olsen, PC | 1 |
| Ferreira, TP | 1 |
| Serra, MF | 1 |
| Farias-Filho, FA | 1 |
| Fonseca, BP | 1 |
| Viola, JP | 1 |
| Cordeiro, RS | 1 |
| Silva, PM | 1 |
| Costa, JC | 1 |
| Martins, MA | 1 |
| Groeben, H | 5 |
| Hoang, BX | 1 |
| Levine, SA | 1 |
| Graeme Shaw, D | 1 |
| Pham, P | 1 |
| Hoang, C | 1 |
| Muraki, M | 1 |
| Iwanaga, T | 1 |
| Haraguchi, R | 1 |
| Kubo, H | 1 |
| Tohda, Y | 1 |
| Silvanus, MT | 3 |
| Beste, M | 4 |
| Peters, J | 4 |
| Harrison, TW | 1 |
| Tattersfield, AE | 1 |
| Grosswendt, T | 1 |
| Silvanus, M | 1 |
1 review available for lidocaine and Bronchial Hyperreactivity
| Article | Year |
|---|---|
Effects of high thoracic epidural anesthesia and local anesthetics on bronchial hyperreactivity.
Topics: Anesthesia, Epidural; Anesthetics, Local; Asthma; Bronchial Hyperreactivity; Humans; Lidocaine; Post | 2000 |
5 trials available for lidocaine and Bronchial Hyperreactivity
| Article | Year |
|---|---|
Combined intravenous lidocaine and inhaled salbutamol protect against bronchial hyperreactivity more effectively than lidocaine or salbutamol alone.
Topics: Administration, Inhalation; Adult; Albuterol; Anesthetics, Local; Blood Pressure; Bronchial Hyperrea | 1998 |
Both intravenous and inhaled lidocaine attenuate reflex bronchoconstriction but at different plasma concentrations.
Topics: Administration, Inhalation; Adult; Anesthetics, Local; Bronchial Hyperreactivity; Bronchial Provocat | 1999 |
Effect of single doses of inhaled lignocaine on FEV1 and bronchial reactivity in asthma.
Topics: Administration, Inhalation; Adult; Albuterol; Anesthetics, Local; Asthma; Bronchial Hyperreactivity; | 1998 |
Combined lidocaine and salbutamol inhalation for airway anesthesia markedly protects against reflex bronchoconstriction.
Topics: Administration, Inhalation; Adult; Aerosols; Albuterol; Anesthesia, Inhalation; Anesthetics, Local; | 2000 |
Lidocaine inhalation for local anaesthesia and attenuation of bronchial hyper-reactivity with least airway irritation. Effect of three different dose regimens.
Topics: Adult; Airway Resistance; Anesthetics, Inhalation; Anesthetics, Local; Asthma; Bronchi; Bronchial Hy | 2000 |
3 other studies available for lidocaine and Bronchial Hyperreactivity
| Article | Year |
|---|---|
Lidocaine-derivative JMF2-1 prevents ovalbumin-induced airway inflammation by regulating the function and survival of T cells.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Bronchial Hyperreactivity; Cytokines; Dexamethasone; I | 2011 |
Bronchial epilepsy or broncho-pulmonary hyper-excitability as a model of asthma pathogenesis.
Topics: Airway Obstruction; Asthma; Bronchi; Bronchial Hyperreactivity; Cell Membrane; gamma-Aminobutyric Ac | 2006 |
Continued inhalation of lidocaine suppresses antigen-induced airway hyperreactivity and airway inflammation in ovalbumin-sensitized guinea pigs.
Topics: Administration, Inhalation; Anesthetics, Local; Animals; Bronchial Hyperreactivity; Bronchoalveolar | 2008 |