Page last updated: 2024-10-28

lidocaine and Brain Infarction

lidocaine has been researched along with Brain Infarction in 5 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Brain Infarction: Tissue NECROSIS in any area of the brain, including the CEREBRAL HEMISPHERES, the CEREBELLUM, and the BRAIN STEM. Brain infarction is the result of a cascade of events initiated by inadequate blood flow through the brain that is followed by HYPOXIA and HYPOGLYCEMIA in brain tissue. Damage may be temporary, permanent, selective or pan-necrosis.

Research Excerpts

ExcerptRelevanceReference
"Following middle cerebral artery occlusion, rats received intensive enriched-rehabilitation (ER) of the impaired forelimb for 4 weeks."1.33Bi-hemispheric contribution to functional motor recovery of the affected forelimb following focal ischemic brain injury in rats. ( Biernaskie, J; Corbett, D; Szymanska, A; Windle, V, 2005)
"Pretreatment with lidocaine (10 microM), but not procaine (50 microM), restored the membrane potential after the reintroduction of oxygen and glucose."1.33Neuroprotective mechanisms of lidocaine against in vitro ischemic insult of the rat hippocampal CA1 pyramidal neurons. ( Higashi, H; Kuroiwa, M; Murai, Y; Niiyama, S; Noguchi, M; Sakamoto, H; Satani, M; Takahashi, K; Tanaka, E; Tsuji, S; Yamada, A, 2005)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Srivatsa, UN1
Ebrahimi, R1
El-Bialy, A1
Wachsner, RY1
Biernaskie, J1
Szymanska, A1
Windle, V1
Corbett, D1
Niiyama, S1
Tanaka, E1
Tsuji, S1
Murai, Y1
Satani, M1
Sakamoto, H1
Takahashi, K1
Kuroiwa, M1
Yamada, A1
Noguchi, M1
Higashi, H1
O'Bryant, A1
Bernier, B1
Jones, TA1
Lei, B1
Cottrell, JE1
Kass, IS1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effectiveness of Add-on Inhibitory Repetitive Transcranial Magnetic Stimulation Over the Contralesional Primary Motor Cortex in Subacute Stroke Patients With Severe Upper Limb Motor Impairment[NCT05505201]24 participants (Anticipated)Interventional2022-11-11Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

5 other studies available for lidocaine and Brain Infarction

ArticleYear
Electrical storm: case series and review of management.
    Journal of cardiovascular pharmacology and therapeutics, 2003, Volume: 8, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Anti-Obesity Agents; B

2003
Bi-hemispheric contribution to functional motor recovery of the affected forelimb following focal ischemic brain injury in rats.
    The European journal of neuroscience, 2005, Volume: 21, Issue:4

    Topics: Animals; Behavior, Animal; Brain Infarction; Brain Ischemia; Forelimb; Functional Laterality; Infarc

2005
Neuroprotective mechanisms of lidocaine against in vitro ischemic insult of the rat hippocampal CA1 pyramidal neurons.
    Neuroscience research, 2005, Volume: 53, Issue:3

    Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Brain Infarction; Calcium Signaling; Diseas

2005
Abnormalities in skilled reaching movements are improved by peripheral anesthetization of the less-affected forelimb after sensorimotor cortical infarcts in rats.
    Behavioural brain research, 2007, Feb-27, Volume: 177, Issue:2

    Topics: Anesthesia; Anesthetics, Local; Animals; Brain Infarction; Feeding Behavior; Functional Laterality;

2007
Neuroprotective effect of low-dose lidocaine in a rat model of transient focal cerebral ischemia.
    Anesthesiology, 2001, Volume: 95, Issue:2

    Topics: Anesthetics, Local; Animals; Blood Gas Analysis; Body Weight; Brain Infarction; Brain Ischemia; Hemo

2001