lidocaine and Bradyarrhythmia studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Research Excerpts

Excerpt	Relevance	Reference
"Lidocaine was an effective treatment for dexmedetomidine-induced bradycardia in healthy research dogs."	9.41	Use of intravenous lidocaine to treat dexmedetomidine-induced bradycardia in sedated and anesthetized dogs. ( Arroyo, L; Hanna, B; Hopkins, A; O'Sullivan, ML; Tisotti, T; Valverde, A, 2021)
" The secondary outcomes included the incidence of total 24 h PONV after surgery, intraoperative remifentanil requirement, postoperative pain visual analogue scale (VAS) scores and fentanyl consumption, the incidence of bradycardia, agitation, shivering, and mouth dry during post-anesthesia care unit (PACU) stay period."	9.41	Effects of lidocaine, dexmedetomidine, and their combination infusion on postoperative nausea and vomiting following laparoscopic hysterectomy: a randomized controlled trial. ( Hu, S; Ju, X; Li, Q; Li, Y; Wang, S; Xu, S, 2021)
"A double-blind, randomised, controlled trial of forty patients was carried out to determine if oral atenolol pretreatment would reduce the incidence of tachycardia during carotid endarterectomy performed under cervical plexus block."	9.07	Prevention of tachycardia with atenolol pretreatment for carotid endarterectomy under cervical plexus blockade. ( Cook, RJ; Davies, MJ; Dysart, RH; Scott, DA; Silbert, BS, 1992)
"This Cochrane review found evidence of low quality to suggest that prophylactic lidocaine has very little or no effect on mortality or ventricular fibrillation in people with acute myocardial infarction."	8.91	Prophylactic lidocaine for myocardial infarction. ( Anand, V; Bangdiwala, S; Martí-Carvajal, AJ; Simancas-Racines, D, 2015)
"Lidocaine has been used in treatment of patients with refractory headache."	8.85	Neuropsychiatric side-effects of lidocaine: examples from the treatment of headache and a review. ( Gil-Gouveia, R; Goadsby, PJ, 2009)
"Lidocaine is an effective therapy for neonatal seizures; however, it is not widely used, presumably due to the risk of cardiac events."	7.81	Lidocaine-Associated Cardiac Events in Newborns with Seizures: Incidence, Symptoms and Contributing Factors. ( de Vries, LS; Schalkwijk, S; Toet, MC; van den Broek, MP; van Rooij, LG; Weeke, LC, 2015)
" This positive lidocaine challenge prompted clinical suspicion of long QT syndrome type 3 (LQT3) and early initiation of mexiletine therapy."	7.76	Neonatal long QT syndrome type 3 predicted by positive lidocaine challenge. ( Bailey, A; DI Maria, M; Howley, LW; Schaffer, MS, 2010)
"We report a 4-year-old child who developed systemic anaphylactic reaction to lidocaine hydrochloride within 15 minutes after a dental procedure."	7.72	Systemic anaphylaxis following local lidocaine administration during a dental procedure. ( Chiu, CY; Hsia, SH; Lai, SH; Lin, TY; Wong, KS, 2004)
"A case of tocainide-induced nodal bradycardia in standard recommended dose is reported."	7.66	Nodal bradycardia induced by tocainide. ( Datta, SK; Mandal, SK, 1983)
"Propofol is a widely used anesthetic drug because of its minor complication and also its fast effect."	6.77	Comparison of effects of ephedrine, lidocaine and ketamine with placebo on injection pain, hypotension and bradycardia due to propofol injection: a randomized placebo controlled clinical trial. ( Ayatollahi, V; Behdad, S; Kargar, S; Yavari, T, 2012)
"His bradycardia was refractory to atropine."	5.48	Profound Prolonged Bradycardia and Hypotension after Interscalene Brachial Plexus Block with Bupivacaine. ( Lee, D; Nelson, M; Reda, L; Reens, A, 2018)
"This toxicity, which manifested as seizures, bradycardia, hypotension, nausea, and emesis, was rapidly recognized and appropriately treated, with a good clinical outcome for the patient."	5.43	Lidocaine Toxicity During Attempted Epistaxis Cautery. ( Nicholas, E; Thornton, MD, 2016)
"Lidocaine was an effective treatment for dexmedetomidine-induced bradycardia in healthy research dogs."	5.41	Use of intravenous lidocaine to treat dexmedetomidine-induced bradycardia in sedated and anesthetized dogs. ( Arroyo, L; Hanna, B; Hopkins, A; O'Sullivan, ML; Tisotti, T; Valverde, A, 2021)
" The secondary outcomes included the incidence of total 24 h PONV after surgery, intraoperative remifentanil requirement, postoperative pain visual analogue scale (VAS) scores and fentanyl consumption, the incidence of bradycardia, agitation, shivering, and mouth dry during post-anesthesia care unit (PACU) stay period."	5.41	Effects of lidocaine, dexmedetomidine, and their combination infusion on postoperative nausea and vomiting following laparoscopic hysterectomy: a randomized controlled trial. ( Hu, S; Ju, X; Li, Q; Li, Y; Wang, S; Xu, S, 2021)
"The evidence is very uncertain about the effect of topical anesthetics (lidocaine) compared to no anesthesia on successful lumbar puncture on first attempt, the number of attempts per lumbar puncture, episodes of bradycardia, episodes of desaturation, and occurrence of apnea."	5.41	Pharmacological interventions for the management of pain and discomfort during lumbar puncture in newborn infants. ( Bruschettini, M; Hedayati, E; Olsson, E; Pessano, S; Romantsik, O, 2023)
"Sick sinus syndrome is caused by sinus node dysfunction that renders it unable to function as a pacemaker."	5.37	Profound bradycardia with lidocaine during anesthesia induction in a silent sick sinus syndrome patient. ( Cho, H; Chung, S; Kim, KO; Lee, K, 2011)
"The routine use of fentanyl and midazolam prior to sheath removal leads to a reduction in pain perception and vasovagal incidence, whilst the routine use of local infiltration during sheath removal should be discouraged as it leads to more pain and a trend to more vasovagal reactions."	5.12	Effect of local anesthesia and intravenous sedation on pain perception and vasovagal reactions during femoral arterial sheath removal after percutaneous coronary intervention. ( French, JK; Juergens, CP; Kiat Ang, C; Leung, DY; Lo, S, 2007)
" The incidence of bradycardia was higher in the groups receiving meperidine."	5.09	Adding low dose meperidine to spinal lidocaine prolongs postoperative analgesia. ( Cicutti, N; Lui, AC; Murto, K, 1999)
"min-1), (2) the incidence of apnea and desaturation of oxygen (< 80%), (3) the degree of sedation, and (4) the serum levels of bilirubin and unbound bilirubin after surgery."	5.08	[Midazolam for anesthetic induction in neonates]. ( Iwasawa, K; Kadosaki, M; Kawakami, K; Mitono, H; Ohata, J; Saito, I, 1998)
"A double-blind, randomised, controlled trial of forty patients was carried out to determine if oral atenolol pretreatment would reduce the incidence of tachycardia during carotid endarterectomy performed under cervical plexus block."	5.07	Prevention of tachycardia with atenolol pretreatment for carotid endarterectomy under cervical plexus blockade. ( Cook, RJ; Davies, MJ; Dysart, RH; Scott, DA; Silbert, BS, 1992)
"This Cochrane review found evidence of low quality to suggest that prophylactic lidocaine has very little or no effect on mortality or ventricular fibrillation in people with acute myocardial infarction."	4.91	Prophylactic lidocaine for myocardial infarction. ( Anand, V; Bangdiwala, S; Martí-Carvajal, AJ; Simancas-Racines, D, 2015)
"Lidocaine has been used in treatment of patients with refractory headache."	4.85	Neuropsychiatric side-effects of lidocaine: examples from the treatment of headache and a review. ( Gil-Gouveia, R; Goadsby, PJ, 2009)
"This study tested the hypothesis that the hypothalamus participates in the decompensatory phase of hemorrhage by measuring Fos immunoreactivity and by inhibiting neuronal activity in selected hypothalamic nuclei with lidocaine or cobalt chloride."	3.83	Hypovolemic hemorrhage induces Fos expression in the rat hypothalamus: Evidence for involvement of the lateral hypothalamus in the decompensatory phase of hemorrhage. ( Göktalay, G; Millington, WR, 2016)
"Lidocaine is an effective therapy for neonatal seizures; however, it is not widely used, presumably due to the risk of cardiac events."	3.81	Lidocaine-Associated Cardiac Events in Newborns with Seizures: Incidence, Symptoms and Contributing Factors. ( de Vries, LS; Schalkwijk, S; Toet, MC; van den Broek, MP; van Rooij, LG; Weeke, LC, 2015)
" This positive lidocaine challenge prompted clinical suspicion of long QT syndrome type 3 (LQT3) and early initiation of mexiletine therapy."	3.76	Neonatal long QT syndrome type 3 predicted by positive lidocaine challenge. ( Bailey, A; DI Maria, M; Howley, LW; Schaffer, MS, 2010)
"The clinical effects of hypokalemia including action potential prolongation and arrhythmogenicity suppressible by lidocaine were reproduced in hypokalemic (3."	3.74	The contribution of refractoriness to arrhythmic substrate in hypokalemic Langendorff-perfused murine hearts. ( Fraser, JA; Grace, AA; Huang, CL; Killeen, MJ; Sabir, IN, 2007)
" Tetrodotoxin and lidocaine slightly reduced heart rate whereas KC 12291 and R 56865, which mainly interact with the persistent component of the sodium current, concentration dependently and potently induced bradycardia."	3.73	Pharmacological characterisation of sodium channels in sinoatrial node pacemaking in the rat heart. ( Le Grand, B; Létienne, R; Vié, B, 2006)
"During neurosurgery for hypophysary adenoma under general anaesthesia in a prone position, a 34 year-old-women received accidental 6 ml intramucosal injection of lidocaine with naphazoline."	3.72	[Cardiac arrest and secondary pulmonary oedema following accidental intramucosal injection of naphazoline in an adult]. ( Delalande, JP; Erhmann, S; Réa, D; Tellier, AC; Villeret, I, 2003)
"We report a 4-year-old child who developed systemic anaphylactic reaction to lidocaine hydrochloride within 15 minutes after a dental procedure."	3.72	Systemic anaphylaxis following local lidocaine administration during a dental procedure. ( Chiu, CY; Hsia, SH; Lai, SH; Lin, TY; Wong, KS, 2004)
" Prenatal treatment with beta-adrenergic blocker (propranolol) and digitalis glycosides was prescribed because of suspicion of long QT syndrome occurring with fetal congestive heart failure."	3.71	Prenatal diagnosis and treatment of fetal long QT syndrome: a case report. ( Chang, IK; Chow, SN; Hsieh, FJ; Kau, ML; Ko, YH; Lee, CN; Shyu, MK, 2002)
" Intravenous (iv) injection of PDG (10 microg/kg), produced hypotension, bradycardia and apnea over a period of time."	3.70	Phenyldiguanide activates cardiac receptors to produce responses by involving three different efferent pathways in anaesthetized rats. ( Bagchi, S; Deshpande, SB, 2000)
"Pathophysiologic mechanisms of bradycardia during epidural anaesthesia (L3-L4 with 1% lidocaine, 38 ml) were evaluated by studying changes in selected cardiovascular and hormonal parameters."	3.68	Reduced left ventricular diameters at onset of bradycardia during epidural anaesthesia. ( Brocks, V; Fernandes, A; Jacobsen, J; Secher, NH; Søfelt, S; Warberg, J, 1992)
" Three bipolar epicardial electrodes recorded left atrial and left and right ventricular depolarizations simultaneously during normal sinus rhythm (NSR) (mean of 5 beats in 11/11 dogs), ST produced by phlebotomy (50 beats in 10 episodes in 6/11) or isoproterenol infusion (105 beats in 21 episodes in 10/11), sinus bradycardia (SB) produced by vagal stimulation (140 beats in 29 episodes in 10/11), and during atrial flutter (AFL) (15 beats in 3 episodes in 3/11) and atrial fibrillation (AF) (152 beats in 31 episodes in 9/11) induced by programmed electrical stimulation."	3.68	Differentiation of sinus rhythms from supraventricular tachydysrhythmias by activation sequence and timing. ( Furman, S; Mercando, AD; Singer, LP; Walsh, CA, 1990)
"Polymorphic ventricular tachyarrhythmias occurred spontaneously during bradycardia in dogs given the inotropic polypeptide anthopleurin-A (AP-A)."	3.67	QTU prolongation and polymorphic ventricular tachyarrhythmias due to bradycardia-dependent early afterdepolarizations. Afterdepolarizations and ventricular arrhythmias. ( Craelius, W; el-Sherif, N; Gough, WB; Henkin, R; Zeiler, RH, 1988)
"In order to define the causal relationship between the use of local anesthetics and fetal bradycardia, paracervical block anesthesia (PCB) with lidocaine of 2-chloroprocaine was induced on 52 occasions to 27 pregnant baboons."	3.66	Bradycardia in the fetal baboon following paracervical block anesthesia. ( Covino, BG; James, LS; Morishima, HO; Stark, RI; Yeh, MN, 1981)
"Fetal heart rate (FHR) decelerations resembling post-paracervical block (PCB) bradycardia were observed immediately after the inadvertent intrauterine injection of lidocaine hydrochloride."	3.66	Fetal heart rate changes after accidental intrauterine lidocaine. ( Miller, FC; Van Dorsten, JP, 1981)
"A case of tocainide-induced nodal bradycardia in standard recommended dose is reported."	3.66	Nodal bradycardia induced by tocainide. ( Datta, SK; Mandal, SK, 1983)
" In anaesthetized guinea-pigs in which ventricular fibrillation had been produced by an intravenous infusion of ouabain, intravenous administration of Kö 1173 caused reversion to sinus rhythm in ten out of ten animals."	3.65	Investigations of the mode of action of a new antidysrhythmic drug, Kö 1173. ( Singh, BN; Vaughan Williams, EM, 1972)
"Propofol is a widely used anesthetic drug because of its minor complication and also its fast effect."	2.77	Comparison of effects of ephedrine, lidocaine and ketamine with placebo on injection pain, hypotension and bradycardia due to propofol injection: a randomized placebo controlled clinical trial. ( Ayatollahi, V; Behdad, S; Kargar, S; Yavari, T, 2012)
"Amiodarone is an extremely potent drug which is effective for both supraventricular as well as ventricular arrhythmias."	2.36	New antiarrhythmic drugs. ( Hess, DS; Scheinman, MM, 1983)
"His bradycardia was refractory to atropine."	1.48	Profound Prolonged Bradycardia and Hypotension after Interscalene Brachial Plexus Block with Bupivacaine. ( Lee, D; Nelson, M; Reda, L; Reens, A, 2018)
"This toxicity, which manifested as seizures, bradycardia, hypotension, nausea, and emesis, was rapidly recognized and appropriately treated, with a good clinical outcome for the patient."	1.43	Lidocaine Toxicity During Attempted Epistaxis Cautery. ( Nicholas, E; Thornton, MD, 2016)
"Sick sinus syndrome is caused by sinus node dysfunction that renders it unable to function as a pacemaker."	1.37	Profound bradycardia with lidocaine during anesthesia induction in a silent sick sinus syndrome patient. ( Cho, H; Chung, S; Kim, KO; Lee, K, 2011)
"Sensitivity and specificity were 50% and 97%, respectively."	1.29	Factors associated with hypotension and bradycardia after epidural blockade. ( Curatolo, M; Orlando, A; Scaramozzino, P; Venuti, FS; Zbinden, AM, 1996)
"Hypotension was significantly greater after external jugular injections; these were also associated with larger reductions in heart rate."	1.29	Cardiorespiratory effects of intravascular injections of lidocaine in the anesthetized rat. Comparisons between arterial and venous routes of administration. ( Pateromichelakis, S, 1995)
" We believe that in these cases the dosage of fentanyl was inadequate and since increasing the dosage of fentanyl to at least 50 micrograms."	1.27	Precipitous bradycardia induced by laryngoscopy in cardiac surgical patients. ( Podolakin, W; Wells, DG, 1987)
"In all animals in whom ventricular arrhythmias were associated with lidocaine, the arrhythmias spontaneously reverted to normal sinus rhythm."	1.27	Cardiovascular toxicity of local anesthetics: an alternative hypothesis. ( Behbehani, MM; Coyle, DE; Denson, DD; Thomas, RD, 1986)
"of lidocaine were reviewed."	1.26	Post--paracervical block bradycardia: its prediction and preventability. ( Crocker, K; Goodlin, RC; Haesslein, HC, 1976)
"Practolol was frequently effective in controlling ventricular dysrhythmias which occurred within the first 24 hours after the onset of symptoms of acute myocardial infarction."	1.25	The effects of practolol on the dysrhythmias complicating acute ischemic heart disease. ( Allen, JD; Pantridge, JF; Shanks, RG, 1975)
"Other arrhythmias occurred to a lesser extent but there was no significant difference between men with and without heart disease."	1.25	Cardiac rhythm in men during cystoscopy. ( Crampton, RS; Gillenwater, JY; Kimbrough, HM, 1975)
"of lidocaine were investigated in 39 patients with impulse formation and conduction defects by means of His-bundle recording and were correlated with plasma lidocaine levels."	1.25	Effects of lidocaine on impulse formation and conduction defects in man. ( Dunning, AJ; Roos, JC, 1975)
"Nine of these had ventricular arrhythmia refractory to drugs."	1.25	Atrial pacing to control heart rate and rhythm in acute cardiac conditions. ( Friesen, WG, 1971)

Research

Studies (163)

Authors

Clinical Trials (4)

Trial Overview

Trial Outcomes

Peak Itch Intensity Between the Vehicle and Active Treatments (Individual and KeAmLi-combo).

Timeframe	Studies, this research(%)	All Research%
pre-1990	107 (65.64)	18.7374
1990's	17 (10.43)	18.2507
2000's	19 (11.66)	29.6817
2010's	17 (10.43)	24.3611
2020's	3 (1.84)	2.80

Authors	Studies
Pessano, S	1
Romantsik, O	1
Olsson, E	1
Hedayati, E	1
Bruschettini, M	1
Kim, H	1
Tisotti, T	1
Valverde, A	1
Hopkins, A	1
O'Sullivan, ML	1
Hanna, B	1
Arroyo, L	1
Xu, S	1
Wang, S	1
Hu, S	1
Ju, X	1
Li, Q	1
Li, Y	1
Tsutsui, Y	1
Sunada, K	1
Nelson, M	1
Reens, A	1
Reda, L	1
Lee, D	1
Clivatti, J	1
Siddiqui, N	1
Goel, A	1
Shaw, M	1
Crisan, I	1
Carvalho, JC	1
Sullivan, RW	1
Ryzewski, M	1
Holland, MG	1
Marraffa, JM	1
Weeke, LC	1
Schalkwijk, S	1
Toet, MC	1
van Rooij, LG	1
de Vries, LS	1
van den Broek, MP	1
Martí-Carvajal, AJ	1
Simancas-Racines, D	1
Anand, V	1
Bangdiwala, S	1
Göktalay, G	2
Millington, WR	2
Nicholas, E	1
Thornton, MD	1
Gil-Gouveia, R	1
Goadsby, PJ	1
Howley, LW	1
DI Maria, M	1
Bailey, A	1
Schaffer, MS	1
Malvasi, A	1
Tinelli, A	1
Stark, M	1
Pontrelli, G	1
Brizzi, A	1
Wetzl, RG	1
Benhamou, D	1
Kim, KO	1
Chung, S	1
Lee, K	1
Cho, H	1
Bohluli, B	1
Schaller, BJ	1
Khorshidi-Khiavi, R	1
Dalband, M	1
Sadr-Eshkevari, P	1
Maurer, P	1
Shih, YH	1
Chen, CH	1
Wang, YM	1
Liu, K	1
Yorgancilar, E	1
Gun, R	1
Yildirim, M	1
Bakir, S	1
Akkus, Z	1
Topcu, I	1
Sharma, R	1
Jain, A	1
Mittal, S	1
Ayatollahi, V	1
Behdad, S	1
Kargar, S	1
Yavari, T	1
Chang, IK	1
Shyu, MK	1
Lee, CN	1
Kau, ML	1
Ko, YH	1
Chow, SN	1
Hsieh, FJ	1
Lahlou, S	1
Bagchi, S	1
Deshpande, SB	1
Chen, S	1
Ma, SX	1
Villeret, I	1
Tellier, AC	1
Erhmann, S	1
Réa, D	1
Delalande, JP	1
DAVIS, JE	1
FRUDENFELD, JC	1
FRUDENFELD, K	1
FRUDENFELD, JH	1
WEBB, AN	1
EADE, MN	1
PARKER, JB	1
Aya, D	1
Fukuda, T	1
Ohkoshi, N	1
Furukawa, H	1
Toyooka, H	1
Chiu, CY	1
Lin, TY	1
Hsia, SH	1
Lai, SH	1
Wong, KS	1
Assi, Z	1
Chang, CC	1
Acharfi, S	1
Wu, MH	1
Chiang, FT	1
Wang, JK	1
Sung, TC	1
Chahine, M	1
Promphan, W	1
Sopontammarak, S	1
Pruekprasert, P	1
Kajornwattanakul, W	1
Kongpattanayothin, A	1
Heckmann, JG	1
Maihöfner, C	1
Lanz, S	1
Rauch, C	1
Neundörfer, B	1
Létienne, R	1
Vié, B	1
Le Grand, B	1
Cavun, S	1
Levendusky, MC	1
Resch, GE	1
Veno, PA	1
Pippa, P	1
Cuomo, P	1
Panchetti, A	1
Scarchini, M	1
Poggi, G	1
D'Arienzo, M	1
Kiat Ang, C	1
Leung, DY	1
Lo, S	1
French, JK	1
Juergens, CP	1
Batra, YK	1
Sharma, A	1
Rajeev, S	1
Sabir, IN	1
Fraser, JA	1
Killeen, MJ	1
Grace, AA	1
Huang, CL	1
Iff, I	1
Moens, Y	1
Langhorne, WH	1
Greenberg, MI	1
Rudolph, W	1
Dirschinger, J	1
Kupper, W	1
Hamm, CW	1
Bleifeld, W	2
Wagner, GS	2
Scheinman, MM	1
Hess, DS	1
Mandal, SK	1
Datta, SK	1
Nikolic, G	1
Demczuk, RJ	1
Grauer, K	1
Hindman, MC	1
Mirakhur, RK	1
Morishima, HO	1
Covino, BG	1
Yeh, MN	1
Stark, RI	1
James, LS	1
Van Dorsten, JP	2
Miller, FC	2
Yeh, SY	1
Vogt, A	1
dal Ri, H	1
Schmidt, G	1
Kreuzer, H	1
Telichowski, C	1
Kochman, K	1
Rółzańska, K	1
Poole, NW	1
Wilson, FW	1
Barber, JH	1
Johannsen, UJ	1
Summers, R	1
Mark, AL	1
Pateromichelakis, S	1
Kurita, T	1
Ohe, T	1
Shimizu, W	1
Hotta, D	1
Shimomura, K	1
Guo, X	1
Schneider, AJ	1
Murray, WB	1
Mentzer, SC	1
Miranda, F	1
Vaduva, S	1
Bruelle, P	1
LeFrant, JY	1
de La Coussaye, JE	1
Peray, PA	1
Desch, G	1
Sassine, A	1
Eledjam, JJ	1
Curatolo, M	1
Scaramozzino, P	1
Venuti, FS	1
Orlando, A	1
Zbinden, AM	1
Ruta, U	1
Gerding, H	1
Möllhoff, T	1
Kawakami, K	1
Ohata, J	1
Kadosaki, M	1
Saito, I	1
Iwasawa, K	1
Mitono, H	1
Avery, JK	1
Murto, K	1
Lui, AC	1
Cicutti, N	1
Watanabe, O	1
Okumura, T	1
Takeda, H	1
Nakamura, W	1
Segawa, K	1
Ito, H	1
Yoshimoto, N	1
Rao, RB	1
Ely, SF	1
Hoffman, RS	1
Roos, JC	1
Dunning, AJ	1
Killip, T	1
Hilwig, RW	1
Dhingra, RC	1
Deedwania, PC	1
Cummings, JM	1
Amat-Y-Leon, F	1
Wu, D	1
Denes, P	1
Rosen, KM	1
Barrillon, A	1
Grand, A	1
Guntheroth, W	1
Klein, HO	1
Jutrin, I	1
Kaplinsky, E	1
Goodlin, RC	1
Crocker, K	1
Haesslein, HC	1
Zacà, F	1
Abate, G	1
Procopio, P	1
Gill, MA	1
Miscia, VF	1
Gourley, DR	1
Allen, JD	1
Pantridge, JF	2
Shanks, RG	2
James, TN	2
Isobe, JH	1
Urthaler, F	1
Kimbrough, HM	1
Crampton, RS	1
Gillenwater, JY	1
Steinbach, K	1
Harti, A	1
Benslama, A	1
M'Jahed, K	1
Zinoun, N	1
Louardi, H	1
Guida, MB	1
Jacobsen, J	1
Søfelt, S	1
Brocks, V	1
Fernandes, A	1
Warberg, J	1
Secher, NH	1
Davies, MJ	1
Dysart, RH	1
Silbert, BS	1
Scott, DA	1
Cook, RJ	1
Walsh, CA	1
Singer, LP	1
Mercando, AD	1
Furman, S	2
Weissenburger, J	1
Davy, JM	1
Chézalviel, F	1
Ertzbischoff, O	1
Poirier, JM	1
Engel, F	1
Lainée, P	1
Penin, E	1
Motté, G	1
Cheymol, G	1
Mehmel, HC	1
el-Sherif, N	1
Zeiler, RH	1
Craelius, W	1
Gough, WB	1
Henkin, R	1
Mantia, AM	1
Phillips, OC	1
Podolakin, W	1
Wells, DG	1
Thomas, RD	1
Behbehani, MM	1
Coyle, DE	1
Denson, DD	1
Bennett, MA	1
Wilner, JM	1
Pentecost, BL	1
Schollmeyer, P	2
Hardewig, A	1
Diedrich, R	1
Campbell, NP	1
Kelly, JG	1
Chaturvedi, NC	1
Strong, JE	1
Conway, DH	1
McLean, KH	1
Ehlers, KH	1
Depaepe, A	1
Bohyn, P	1
De Maertelaere, M	1
Dernier, J	1
Cloetens, W	1
De Mey, D	1
Kühn, P	1
Koller, H	1
Kohn, P	1
Holzhey, P	1
Hartl, O	1
Clodi, PH	1
Shillingford, JP	1
Bender, F	2
Sehhati, G	1
Frey, R	1
Mildner, R	1
Robinson, SJ	1
Strubelt, O	1
Back, G	1
Uhl, E	1
Zetler, G	1
Grossman, JI	1
Rubin, IL	1
Murmann, W	1
Almirante, L	1
Saccani-Guelfi, M	1
Lasser, RP	1
Zoneraich, S	1
Zoneraich, O	1
Merx, KW	1
Heinrich, KW	1
Effert, S	1
Chung, EK	2
Awalt, CH	1
Rydén, L	1
Cullhed, I	1
Wasir, H	1
Humphries, JO	1
Parameswaran, R	1
Kahn, D	1
Monheit, R	1
Goldberg, H	1
Marriott, HJ	2
Phillips, K	1
Hamilton, LA	1
Gottschalk, W	1
Vohra, JK	1
Keats, AS	1
Strong, MJ	1
Girgis, KZ	1
Goldstein, A	1
Lemberg, L	1
Castellanos, A	1
Arcebal, AG	1
Iyengar, RN	1
Patton, RD	1
Mulcahy, R	1
Amankwah, KS	1
Esposito, JM	1
Singh, BN	1
Vaughan Williams, EM	1
Liu, CK	1
Lee, JY	1
Jeresaty, RM	1
Kahn, AH	1
Landry, AB	1
Hickl, EJ	1
Gennser, G	1
Lyngborg, K	1
Jacobsen, JG	1
Vasicka, A	1
Robertazzi, R	1
Raji, M	1
Scheffs, J	1
Kosmowski, J	1
Goei, T	1
Schüller, H	1
Stock, E	1
Frink, RJ	1
Danzig, R	1
Hendrickson, M	1
Schmidt, E	1
Gradaus, D	1
Kozaki, M	1
Nakayama, S	1
Oguri, K	1
Terry, G	1
Vellani, CW	1
Higgins, MR	1
Doig, A	1
Esser, H	1
Fricke, G	1
Martin, RD	1
Zilianti, M	1
Salazar, JR	1
Aller, J	1
Agüero, O	1
Staffen, A	1
Wolner, E	1
Escher, DJ	1
Boba, A	1
Linkie, DM	1
Plotz, EJ	1
Dreifus, LS	1
Bernier, G	1
Turcot, MJ	1
Alexander, JP	1
Friesen, WG	1
Merideth, J	1
Giuliani, ER	1
Barnet, RJ	1
Redding, JS	1
Pearson, JW	1
Zipes, DP	1

Trial	Phase	Enrollment	Study Type	Start Date	Status
Effects of Combination Intravenous Dexmedetomidine and Lidocaine on Postoperative Nausea and Vomiting After Laparoscopic Hysterectomy With General Anesthesia[NCT03809923]		240 participants (Actual)	Interventional	2019-06-01	Completed
Antipruritic Effect of Topical Ketamine, Amitriptyline, and Lidocaine[NCT03096444]	Phase 2	13 participants (Actual)	Interventional	2017-05-23	Terminated (stopped due to Efficacy was not seen after interim analysis)
Is the Application of Scopolamine Patch With or Without Intra-operative Acupressure Point P6 Stimulation More Effective Than Intra-operative Acupressure Point P6 Stimulation Alone?[NCT02960113]	Phase 4	240 participants (Actual)	Interventional	2016-05-31	Completed
A Study of the Trigeminal Cardio-Reflex in Endodontic and Other Dental Treatment[NCT02745782]		500 participants (Anticipated)	Observational	2014-10-31	Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

"Peak itch intensity between the vehicle and 4 other active treatments (individual ketamine, amitriptyline, or lidocaine, and KeAmLi-combo). Itch intensity was measured on a 100mm scale visual analog scale for 10 minutes. 0 was weighted with no itch and 100 was weighted with most itch imaginable." (NCT03096444)
Timeframe: 10 minutes

Mechanical Thresholds (Mechanical Detection and Pain).

Intervention	Intensity score (Mean)
Topical KeAmLi Combo	62.7
Topical Ketamine	63.1
Topical Amitriptyline	69.2
Topical Lidocaine	65.8
Topical Vehicle	61.9

Assess mechanical detection and pain thresholds using von Frey filaments stimulators (measured in force mN) to calculate the final threshold as the geometric mean of five series of ascending and descending stimuli. (NCT03096444)
Timeframe: 5 minutes

Thermal Threshold Detection (Warmth and Heat Pain)

Intervention	mN (Mean)
	Mechanical Detection Threshold	Mechanical Pain Threshold
Topical Amitriptyline	3.573423965	152.4768146
Topical KeAmLi Combo	3.519376956	152.3293608
Topical Ketamine	3.464204768	135.9
Topical Lidocaine	3.546037659	126.9
Topical Vehicle	3.525692637	148.7138273

Two standardized quantitative sensory tests are performed to measure warmth detection threshold (assesses the threshold of which warmth sensation is first detected) and heat pain threshold (assesses the threshold at which heat pain sensation is first detected). Measured in change in celsius. (NCT03096444)
Timeframe: 3 minutes

Level of Nausea After Eversion of the Uterus

Intervention	Degrees celsius (Mean)
	Warm Detection Threshold	Heat Pain Threshold
Topical Amitriptyline	33.9	40.0
Topical KeAmLi Combo	33.6	39.8
Topical Ketamine	34.0	40.0
Topical Lidocaine	33.7	39.4
Topical Vehicle	33.8	39.7

Patients offer their subjective assessments of the level of nausea on a scale of 0-10 (0 = no nausea, 10 = worst nausea ever experienced) after eversion of the uterus. The investigators will analyze if there is a statistically significant difference between the number of patients that experience nausea in each group at this point. Patients that report nausea (1 or more on our scale) will be recorded as that they have experienced nausea. (NCT02960113)
Timeframe: After eversion of the uterus until replacement of the uterus

Level of Nausea After Replacement of the Uterus

Intervention	units on a scale (Mean)
Scopolamine Patch	1.28
Acupressure Point P6	1.09
Scopolamine Patch + Acupressure Point P6	1.40

Patients offer their subjective assessments of the level of nausea on a scale of 0-10 (0 = no nausea, 10 = worst nausea ever experienced) after replacement of the uterus. The investigators will analyze if there is a statistically significant difference between the number of patients that experience nausea in each group at this point. Patients that report nausea (1 or more on our scale) will be recorded as that they have experienced nausea. (NCT02960113)
Timeframe: After replacement of the uterus and to the next 15 minutes

Level of Nausea After the Administration of the Regional Anesthesia Medications

Intervention	units on a scale (Mean)
Scopolamine Patch	2.19
Acupressure Point P6	2.19
Scopolamine Patch + Acupressure Point P6	2.51

Patients offer their subjective assessments of the level of nausea on a scale of 0-10 (0 = no nausea, 10 = worst nausea ever experienced) after the administration of the regional anesthesia medications. The investigators will analyze if there is a statistically significant difference between the number of patients that experience nausea in each group at this point. Patients that report nausea (1 or more on our scale) will be recorded as that they have experienced nausea. (NCT02960113)
Timeframe: From administration of anaesthesia until eversion of uterus

Level of Nausea Upon Arrival to the Post-operative Recovery Room

Intervention	units on a scale (Mean)
Scopolamine Patch	2.71
Acupressure Point P6	2.57
Scopolamine Patch + Acupressure Point P6	2.84

Patients offer their subjective assessments of the level of nausea on a scale of 0-10 (0 = no nausea, 10 = worst nausea ever experienced) upon arrival to the post-operative recovery room. The investigators will analyze if there is a statistically significant difference between the number of patients that experience nausea in each group at this point. Patients that report nausea (1 or more on our scale) will be recorded as that they have experienced nausea. (NCT02960113)
Timeframe: 15 minutes after replacement of the uterus to arrival at post-anaesthesia care unit

Number of Patients With Nausea

Intervention	units on a scale (Mean)
Scopolamine Patch	0.18
Acupressure Point P6	0.25
Scopolamine Patch + Acupressure Point P6	0.23

The investigators will analyze if there is a statistically significant difference between the number of patients that experience nausea at any point during the surgical procedure in each group. (NCT02960113)
Timeframe: Throughout the entire surgical procedure

Number of Patients With Vomiting

Intervention	Participants (Count of Participants)
Scopolamine Patch	40
Acupressure Point P6	39
Scopolamine Patch + Acupressure Point P6	46

The investigators will perform objective assessments of whether or not the patients have vomited during the procedure. The investigators will then analyze if there is a statistically significant difference between the number of patients that vomit in each group. (NCT02960113)
Timeframe: Throughout the surgical procedure

Number of Patients With Vomiting After Eversion of the Uterus

Intervention	Participants (Count of Participants)
Scopolamine Patch	24
Acupressure Point P6	25
Scopolamine Patch + Acupressure Point P6	31

Objective assessments of whether or not the patients have vomited at this point in the surgical procedure will be done. The investigators will analyze if there is a statistically significant difference between the number of patients that vomit in each group. (NCT02960113)
Timeframe: After eversion of to replacement of the uterus

Number of Patients With Vomiting After Replacement of the Uterus

Intervention	Participants (Count of Participants)
Scopolamine Patch	8
Acupressure Point P6	6
Scopolamine Patch + Acupressure Point P6	9

Number of Patients With Vomiting After the Administration of the Regional Anesthesia Medications

Intervention	Participants (Count of Participants)
Scopolamine Patch	10
Acupressure Point P6	15
Scopolamine Patch + Acupressure Point P6	12

Number of Patients With Vomiting Upon Arrival to the Post-operative Recovery Room

Intervention	Participants (Count of Participants)
Scopolamine Patch	20
Acupressure Point P6	15
Scopolamine Patch + Acupressure Point P6	20

Satisfaction With Intraoperative Antiemetic Treatment

Intervention	Participants (Count of Participants)
Scopolamine Patch	1
Acupressure Point P6	1
Scopolamine Patch + Acupressure Point P6	4

Patients are asked their nausea and vomiting treatment satisfaction (0 = Not Satisfied, 10 = Extremely Satisfied). Patients are also asked their overall satisfaction with the procedure (0 = Not Satisfied, 10 = Extremely Satisfied). (NCT02960113)
Timeframe: Throughout the surgical procedure

Article	Year
Pharmacological interventions for the management of pain and discomfort during lumbar puncture in newborn infants. The Cochrane database of systematic reviews, 2023, 09-28, Volume: 9 Topics: Analgesics; Anesthetics, Local; Apnea; Bradycardia; Fentanyl; Humans; Hypnotics and Sedatives; Infan	2023
Prophylactic lidocaine for myocardial infarction. The Cochrane database of systematic reviews, 2015, Aug-21, Issue:8 Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bradycardia; Humans; Lidocaine; Myocardial Infarction;	2015
Neuropsychiatric side-effects of lidocaine: examples from the treatment of headache and a review. Cephalalgia : an international journal of headache, 2009, Volume: 29, Issue:5 Topics: Adult; Aged; Anesthetics, Local; Bradycardia; Female; Headache; Humans; Hypertension; Lidocaine; Mal	2009
Arrhythmias in acute myocardial infarction. The Medical clinics of North America, 1984, Volume: 68, Issue:4 Topics: Arrhythmias, Cardiac; Bradycardia; Heart Block; Humans; Lidocaine; Myocardial Infarction; Pacemaker,	1984
New antiarrhythmic drugs. American journal of surgery, 1983, Volume: 145, Issue:6 Topics: Amiodarone; Angina Pectoris; Anti-Arrhythmia Agents; Blood Circulation; Bradycardia; Diltiazem; Half	1983
Arrhythmias during myocardial infarction: Mechanisms, significance, and therapy. Cardiovascular clinics, 1980, Volume: 11, Issue:1 Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Atrioventricular Node; Bradycardia; Heart Block; Humans;	1980
Cardiac arrhythmias in the dog: detection and treatment. Journal of the American Veterinary Medical Association, 1976, Oct-15, Volume: 169, Issue:8 Topics: Animals; Arrhythmia, Sinus; Arrhythmias, Cardiac; Atrial Fibrillation; Bradycardia; Cardiac Complexe	1976
[Incompatibility and interference of the major cardiologic drugs. Their undesirable effects]. La Revue du praticien, 1976, Dec-21, Volume: 26, Issue:59 Topics: Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Antihypertensive Agents; Bradycardia; Cardiac Glyc	1976
The treatment of common cardiac arrhythmias. Journal of the American Pharmaceutical Association, 1976, Volume: 16, Issue:1 Topics: Aged; Anti-Arrhythmia Agents; Arrhythmia, Sinus; Arrhythmias, Cardiac; Atrial Fibrillation; Atropine	1976
[Cardiac arrhythmias. I. Pathogenesis and clinical significance]. Medizinische Klinik, 1971, Apr-16, Volume: 66, Issue:16 Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillat	1971
Supraventricular and ventricular dysrhythmias in infants and children. Cardiovascular clinics, 1972, Volume: 4, Issue:3 Topics: Arrhythmias, Cardiac; Bradycardia; Cardiac Complexes, Premature; Child; Child, Preschool; Deafness;	1972
Treatment of cardiac arrhythmias. Pediatric clinics of North America, 1964, Volume: 11, Issue:2 Topics: Adams-Stokes Syndrome; Arrhythmia, Sinus; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter;	1964
Life-threatening arrhythmias. The Medical clinics of North America, 1973, Volume: 57, Issue:6 Topics: Adult; Aged; Angina Pectoris; Arrhythmias, Cardiac; Bradycardia; Electrocardiography; Female; Heart	1973
The prophylactic use of anti-arrhythmic drugs in acute myocardial infarction. Singapore medical journal, 1973, Volume: 14, Issue:3 Topics: Acute Disease; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atropine; Bradycardia; Death, Sud	1973
Cardiac arrhythmias. Rationale of drug therapy. Singapore medical journal, 1973, Volume: 14, Issue:3 Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atropine; Bradycardia; Bretylium Compounds; Cardiac Gl	1973
Antiarrhythmic drugs. Clinical anesthesia, 1974, Volume: 10, Issue:1 Topics: Anesthesia; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bradycardia; Digitalis Glycosides; Heart;	1974
The treatment of arrhythmias following acute myocardial infarction. The Medical clinics of North America, 1971, Volume: 55, Issue:2 Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Atropine; Bradycardia; Coronary Care Units; Digitalis Gly	1971
Management of arrhythmias in acute myocardial infarction. American family physician, 1971, Volume: 4, Issue:1 Topics: Acid-Base Equilibrium; Adams-Stokes Syndrome; Arrhythmias, Cardiac; Atropine; Bradycardia; Cardiac O	1971
Intensive coronary care: current status and future prospects. Cardiovascular clinics, 1971, Volume: 2, Issue:3 Topics: Analgesics; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Atropine; Bradycardia; Coro	1971
Management of cardiac dysrhythmias complicating acute myocardial infarction. Geriatrics, 1968, Volume: 23, Issue:9 Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Atropine; Bradycardia; Bretylium Compound	1968

Article	Year
Use of intravenous lidocaine to treat dexmedetomidine-induced bradycardia in sedated and anesthetized dogs. Veterinary anaesthesia and analgesia, 2021, Volume: 48, Issue:2 Topics: Anesthetics, Inhalation; Animals; Bradycardia; Dexmedetomidine; Dog Diseases; Dogs; Female; Heart Ra	2021
Effects of lidocaine, dexmedetomidine, and their combination infusion on postoperative nausea and vomiting following laparoscopic hysterectomy: a randomized controlled trial. BMC anesthesiology, 2021, 08-04, Volume: 21, Issue:1 Topics: Adult; Anesthesia, General; Bradycardia; Dexmedetomidine; Double-Blind Method; Drug Therapy, Combina	2021
Trigeminocardiac reflex, bilateral sagittal split ramus osteotomy, Gow-Gates block: a randomized controlled clinical trial. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2011, Volume: 69, Issue:9 Topics: Adult; Anesthesia, General; Anesthetics, Local; Bradycardia; Cross-Over Studies; Double-Blind Method	2011
Comparison of effects of ephedrine, lidocaine and ketamine with placebo on injection pain, hypotension and bradycardia due to propofol injection: a randomized placebo controlled clinical trial. Acta medica Iranica, 2012, Volume: 50, Issue:9 Topics: Adult; Anesthetics, Intravenous; Bradycardia; Double-Blind Method; Ephedrine; Female; Humans; Hypote	2012
High volume and low concentration of anaesthetic solution in the perivascular interscalene sheath determines quality of block and incidence of complications. European journal of anaesthesiology, 2006, Volume: 23, Issue:10 Topics: Adrenergic Agonists; Adult; Aged; Anesthetics, Local; Brachial Plexus; Bradycardia; Bupivacaine; Epi	2006
Effect of local anesthesia and intravenous sedation on pain perception and vasovagal reactions during femoral arterial sheath removal after percutaneous coronary intervention. International journal of cardiology, 2007, Apr-04, Volume: 116, Issue:3 Topics: Aged; Anesthetics, Local; Angioplasty, Balloon, Coronary; Bradycardia; Cardiovascular Diseases; Cons	2007
Spacing the injection interval with paracervical block: a randomized study. Obstetrics and gynecology, 1981, Volume: 58, Issue:6 Topics: Adult; Anesthesia, Local; Anesthesia, Obstetrical; Bradycardia; Female; Humans; Infant, Newborn; Inj	1981
"Helper:" A critical events prompter for unexpected emergencies. Journal of clinical monitoring, 1995, Volume: 11, Issue:6 Topics: Algorithms; Anesthesia, General; Anesthesiology; Anti-Arrhythmia Agents; Bradycardia; Clinical Proto	1995
[Effect of locally applied lidocaine on expression of the oculocardiac reflex]. Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 1997, Volume: 94, Issue:5 Topics: Adolescent; Adult; Aged; Anesthesia, General; Bradycardia; Child; Child, Preschool; Female; Humans;	1997
[Midazolam for anesthetic induction in neonates]. Masui. The Japanese journal of anesthesiology, 1998, Volume: 47, Issue:5 Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Anesthetics, Local; Apnea; Bilirubin; Blood Press	1998
Adding low dose meperidine to spinal lidocaine prolongs postoperative analgesia. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1999, Volume: 46, Issue:4 Topics: Adjuvants, Anesthesia; Aged; Aged, 80 and over; Analgesia; Analgesics, Opioid; Analysis of Variance;	1999
Prevention of tachycardia with atenolol pretreatment for carotid endarterectomy under cervical plexus blockade. Anaesthesia and intensive care, 1992, Volume: 20, Issue:2 Topics: Aged; Atenolol; Bradycardia; Cervical Plexus; Creatine Kinase; Double-Blind Method; Electrocardiogra	1992
Controlled trial of lignocaine in prophylaxis of ventricular arrhythmias complicating myocardial infarction. Lancet (London, England), 1970, Oct-31, Volume: 2, Issue:7679 Topics: Adult; Age Factors; Aged; Arrhythmias, Cardiac; Bradycardia; Clinical Trials as Topic; Female; Heart	1970
Mexiletine (Kö 1173) in the management of ventricular dysrhythmias. Lancet (London, England), 1973, Aug-25, Volume: 2, Issue:7826 Topics: Administration, Oral; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bradycardia; Cardiac Complexes,	1973
Controlled trial of prophylatic treatment with lidocaine in acute myocardial infarction. European journal of clinical pharmacology, 1973, Volume: 6, Issue:2 Topics: Adult; Aged; Blood Pressure; Bradycardia; Clinical Trials as Topic; Depression, Chemical; Electrocar	1973

Article	Year
Sudden arrhythmia followed by bradycardia during sagittal split ramus osteotomy: trigeminocardiac reflex. BMJ case reports, 2019, Dec-02, Volume: 12, Issue:12 Topics: Administration, Intravenous; Anti-Arrhythmia Agents; Bradycardia; Cholinergic Antagonists; Electroca	2019
A Combination of Dexmedetomidine and Lidocaine Is a Cardiovascularly Safe Dental Local Anesthetic for Hypertensive Rats Treated With a Nonselective β-Adrenergic Antagonist. Anesthesia progress, 2017,Winter, Volume: 64, Issue:4 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Antagonists; Anesthesia, Dental; Anesthesia, L	2017
Profound Prolonged Bradycardia and Hypotension after Interscalene Brachial Plexus Block with Bupivacaine. The Journal of emergency medicine, 2018, Volume: 54, Issue:3 Topics: Aged; Anesthetics, Local; Atropine; Brachial Plexus Block; Bradycardia; Bupivacaine; Emergency Servi	2018
Quality of labour neuraxial analgesia and maternal satisfaction at a tertiary care teaching hospital: a prospective observational study. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2013, Volume: 60, Issue:8 Topics: Adjuvants, Anesthesia; Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesia, Patient-Contro	2013
Compounded ointment results in severe toxicity in a pediatric patient. Pediatric emergency care, 2013, Volume: 29, Issue:11 Topics: Administration, Cutaneous; Amines; Analgesics; Body Surface Area; Bradycardia; Clonidine; Combined M	2013
Lidocaine-Associated Cardiac Events in Newborns with Seizures: Incidence, Symptoms and Contributing Factors. Neonatology, 2015, Volume: 108, Issue:2 Topics: Anticonvulsants; Birth Weight; Bradycardia; Databases, Factual; Female; Gestational Age; Heart Rate;	2015
Hypovolemic hemorrhage induces Fos expression in the rat hypothalamus: Evidence for involvement of the lateral hypothalamus in the decompensatory phase of hemorrhage. Neuroscience, 2016, May-13, Volume: 322 Topics: Animals; Bradycardia; Cobalt; Disease Models, Animal; Hemorrhage; Hemostatics; Hypothalamus; Hypovol	2016
Lidocaine Toxicity During Attempted Epistaxis Cautery. The Journal of emergency medicine, 2016, Volume: 51, Issue:3 Topics: Anesthesia, Local; Anesthetics, Local; Bradycardia; Cautery; Epistaxis; Humans; Lidocaine; Male; Sei	2016
Neonatal long QT syndrome type 3 predicted by positive lidocaine challenge. Pacing and clinical electrophysiology : PACE, 2010, Volume: 33, Issue:3 Topics: Anti-Arrhythmia Agents; Bradycardia; Electrocardiography; Female; Humans; Infant, Newborn; Lidocaine	2010
Low-dose sequential combined spinal-epidural anaesthesia in elective Stark caesarean section: a preliminary cohort study. European review for medical and pharmacological sciences, 2010, Volume: 14, Issue:3 Topics: Adult; Analgesics, Opioid; Anesthesia, Epidural; Anesthesia, Spinal; Anesthetics, Local; Bradycardia	2010
Profound bradycardia with lidocaine during anesthesia induction in a silent sick sinus syndrome patient. Journal of clinical anesthesia, 2011, Volume: 23, Issue:3 Topics: Aged; Anesthesia; Anesthetics, Local; Bradycardia; Electrocardiography; Humans; Lidocaine; Male; Sic	2011
Successful reversal of bupivacaine and lidocaine-induced severe junctional bradycardia by lipid emulsion following infraclavicular brachial plexus block in a uremic patient. Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists, 2011, Volume: 49, Issue:2 Topics: Aged; Anesthetics, Local; Brachial Plexus; Bradycardia; Bupivacaine; Fat Emulsions, Intravenous; Fem	2011
Determination of trigeminocardiac reflex during rhinoplasty. International journal of oral and maxillofacial surgery, 2012, Volume: 41, Issue:3 Topics: Adult; Anesthetics, Local; Blood Pressure; Bradycardia; Epinephrine; Female; Heart Rate; Humans; Hyp	2012
Bradycardia and hypertension: an unusual presentation of an intravascular epidural test dose during combined spinal and epidural anaesthesia. Anaesthesia and intensive care, 2012, Volume: 40, Issue:5 Topics: Adult; Anesthesia, Epidural; Anesthesia, Spinal; Bradycardia; Epinephrine; Female; Humans; Hypertens	2012
Prenatal diagnosis and treatment of fetal long QT syndrome: a case report. Prenatal diagnosis, 2002, Volume: 22, Issue:13 Topics: Adult; Bradycardia; Bundle-Branch Block; Electrocardiography; Female; Fetal Diseases; Heart Block; H	2002
Mechanisms underlying the cardiovascular responses to spinal dopamine receptor stimulation by apomorphine in anesthetized rats. Neuroscience letters, 2003, Jan-02, Volume: 335, Issue:3 Topics: Adrenalectomy; Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Apomorphine; Atenolol;	2003
Phenyldiguanide activates cardiac receptors to produce responses by involving three different efferent pathways in anaesthetized rats. Indian journal of experimental biology, 2000, Volume: 38, Issue:9 Topics: Adrenergic alpha-Antagonists; Anesthetics, Local; Animals; Apnea; Biguanides; Blood Pressure; Bradyc	2000
Nitric oxide in the gracile nucleus mediates depressor response to acupuncture (ST36). Journal of neurophysiology, 2003, Volume: 90, Issue:2 Topics: Animals; Arginine; Blood Pressure; Bradycardia; Electroacupuncture; Heart Rate; Lidocaine; Male; Med	2003
[Cardiac arrest and secondary pulmonary oedema following accidental intramucosal injection of naphazoline in an adult]. Annales francaises d'anesthesie et de reanimation, 2003, Volume: 22, Issue:5 Topics: Adenoma; Adrenergic alpha-Agonists; Adult; Anesthesia, General; Anesthetics, Local; Blood Pressure;	2003
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SOME OBSERVATIONS ON FOETAL HEART DURING LABOUR. Proceedings of the Royal Society of Medicine, 1965, Volume: 58 Topics: Anesthesia; Anesthesia, Obstetrical; Anesthesia, Spinal; Bradycardia; Electrocardiography; Female; F	1965
[Regional anesthesia for a patient with stiff-person syndrome]. Masui. The Japanese journal of anesthesiology, 2004, Volume: 53, Issue:1 Topics: Aged; Anesthesia, Conduction; Bradycardia; Humans; Lidocaine; Male; Pacemaker, Artificial; Propofol;	2004
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Dengue myocarditis. The Southeast Asian journal of tropical medicine and public health, 2004, Volume: 35, Issue:3 Topics: Adolescent; Anti-Arrhythmia Agents; Bradycardia; Electrocardiography; Epinephrine; Heart Rate; Human	2004
Transient tetraplegia after cervical facet joint injection for chronic neck pain administered without imaging guidance. Clinical neurology and neurosurgery, 2006, Volume: 108, Issue:7 Topics: Adult; Anesthetics, Local; Arteries; Atropine; Bradycardia; Cervical Vertebrae; Chronic Disease; Dia	2006
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[Therapy of acute myocardial infarct before hospital admission]. Der Internist, 1982, Volume: 23, Issue:12 Topics: Aged; Atropine; Bradycardia; Cardiac Complexes, Premature; Diagnosis, Differential; First Aid; Furos	1982
Nodal bradycardia induced by tocainide. Postgraduate medical journal, 1983, Volume: 59, Issue:690 Topics: Aged; Bradycardia; Female; Humans; Lidocaine; Tocainide	1983
Lidocaine bradycardia. Heart & lung : the journal of critical care, 1984, Volume: 13, Issue:3 Topics: Bradycardia; Electrocardiography; Humans; Infusions, Parenteral; Lidocaine; Male; Middle Aged	1984
Significant sinus bradycardia following intravenous lidocaine injection. Anesthesiology, 1984, Volume: 60, Issue:1 Topics: Aged; Arrhythmia, Sinus; Bradycardia; Humans; Injections, Intravenous; Intraoperative Complications;	1984
Major complications in continuous epidural anesthesia. Chinese medical journal, 1980, Volume: 93, Issue:3 Topics: Adult; Anesthesia, Epidural; Bradycardia; Female; Hemorrhage; Humans; Hypertension, Portal; Lidocain	1980
Early management of myocardial infarction. American family physician, 1983, Volume: 28, Issue:2 Topics: Adult; Bradycardia; Coronary Disease; Heart Block; Hemodynamics; Humans; Lidocaine; Male; Monitoring	1983
Bradycardia with laryngeal spraying in children. Acta anaesthesiologica Scandinavica, 1982, Volume: 26, Issue:2 Topics: Adolescent; Adult; Age Factors; Anesthesia, Local; Atropine; Bradycardia; Child; Child, Preschool; G	1982
Bradycardia in the fetal baboon following paracervical block anesthesia. American journal of obstetrics and gynecology, 1981, Aug-01, Volume: 140, Issue:7 Topics: Anesthesia, Local; Anesthesia, Obstetrical; Animals; Bradycardia; Female; Fetal Diseases; Fetus; Hem	1981
Suppression of the depressor cardiac reflex during coronary occlusion by lidocaine--evidence for a central nervous site of action. European heart journal, 1981, Volume: 2, Issue:5 Topics: Animals; Blood Pressure; Bradycardia; Cats; Coronary Disease; Depression, Chemical; Heart; Heart Rat	1981
[Dangerous bradycardia after xylocaine treatment of acute myocardial infarct]. Kardiologia polska, 1980, Volume: 23, Issue:5 Topics: Acute Disease; Bradycardia; Humans; Lidocaine; Male; Middle Aged; Myocardial Infarction	1980
The treatment of acute myocardial infarction. Scottish medical journal, 1980, Volume: 25, Issue:3 Topics: Acute Disease; Atropine; Bradycardia; Humans; Lidocaine; Myocardial Infarction; Surveys and Question	1980
Fetal heart rate changes after accidental intrauterine lidocaine. Obstetrics and gynecology, 1981, Volume: 57, Issue:2 Topics: Adult; Anesthesia, Obstetrical; Bradycardia; Female; Fetal Heart; Humans; Infant, Newborn; Lidocaine	1981
Gastric dilation during stimulation of cardiac sensory receptors. Circulation, 1981, Volume: 63, Issue:4 Topics: Animals; Bradycardia; Coronary Circulation; Dogs; Female; Heart; Heart Rate; Hypotension; Lidocaine;	1981
Cardiorespiratory effects of intravascular injections of lidocaine in the anesthetized rat. Comparisons between arterial and venous routes of administration. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 1995, Volume: 79, Issue:1 Topics: Animals; Blood Pressure; Bradycardia; Carotid Artery, Internal; Dose-Response Relationship, Drug; He	1995
Early afterdepolarization in a patient with complete atrioventricular block and torsades de pointes. Pacing and clinical electrophysiology : PACE, 1993, Volume: 16, Issue:1 Pt 1 Topics: Action Potentials; Aged; Bradycardia; Cardiac Pacing, Artificial; Electrocardiography; Female; Heart	1993
[A retrospective analysis of continuous cervical epidural block]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 1993, Volume: 15, Issue:6 Topics: Adolescent; Adult; Aged; Anesthesia, Epidural; Bradycardia; Cervical Plexus; Female; Humans; Hypoten	1993
Comparative electrophysiologic and hemodynamic effects of several amide local anesthetic drugs in anesthetized dogs. Anesthesia and analgesia, 1996, Volume: 82, Issue:3 Topics: Amides; Anesthetics, Local; Animals; Aorta; Atrial Function; Atrioventricular Node; Blood Pressure;	1996
Factors associated with hypotension and bradycardia after epidural blockade. Anesthesia and analgesia, 1996, Volume: 83, Issue:5 Topics: Adjuvants, Anesthesia; Adult; Aged; Analgesia, Epidural; Anesthesia, Epidural; Anesthetics, Local; B	1996
Routine procedure--bad outcome. Tennessee medicine : journal of the Tennessee Medical Association, 1998, Volume: 91, Issue:7 Topics: Aged; Anesthetics, Local; Bradycardia; Brain Diseases; Bronchoscopy; Drug Overdose; Heart Arrest; Hu	1998
Nicorandil, a potassium channel opener, abolished torsades de pointes in a patient with complete atrioventricular block. Pacing and clinical electrophysiology : PACE, 1999, Volume: 22, Issue:4 Pt 1 Topics: Aged; Anesthetics, Local; Anti-Arrhythmia Agents; Bradycardia; Cardiotonic Agents; Electrocardiograp	1999
Deaths related to liposuction. The New England journal of medicine, 1999, May-13, Volume: 340, Issue:19 Topics: Adult; Anesthetics, Local; Bradycardia; Cause of Death; Fatal Outcome; Female; Humans; Hypotension;	1999
Effects of lidocaine on impulse formation and conduction defects in man. American heart journal, 1975, Volume: 89, Issue:6 Topics: Adult; Aged; Arrhythmia, Sinus; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Atriovent	1975
Arrhythmias in myocardial infarction. The Medical clinics of North America, 1976, Volume: 60, Issue:2 Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atropine; Bradycardia; Cardiac Complexes, Premature; D	1976
Electrophysiologic effects of lidocaine on sinus node and atrium in patients with and without sinoatrial dysfunction. Circulation, 1978, Volume: 57, Issue:3 Topics: Adult; Aged; Bradycardia; Electrocardiography; Electrophysiology; Female; Heart Atria; Humans; Lidoc	1978
Neonatal and pediatric cardiovascular crises. JAMA, 1975, Apr-14, Volume: 232, Issue:2 Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Bradycardia; Cardiovascular Diseases; Digoxin; Emerge	1975
Cerebral and cardiac toxicity of a small dose of lignocaine. British heart journal, 1975, Volume: 37, Issue:7 Topics: Arrhythmias, Cardiac; Bradycardia; Electrocardiography; Epilepsy, Tonic-Clonic; Humans; Injections,	1975
Post--paracervical block bradycardia: its prediction and preventability. American journal of obstetrics and gynecology, 1976, Jul-01, Volume: 125, Issue:5 Topics: Anesthesia, Local; Anesthesia, Obstetrical; Atropine; Bradycardia; Cervix Uteri; Female; Fetal Heart	1976
[Ventricular fibrillation in "sick sinus syndrome"]. Bollettino della Societa italiana di cardiologia, 1976, Volume: 21, Issue:4 Topics: Aged; Bradycardia; Female; Humans; Lidocaine; Potassium; Sinoatrial Node; Ventricular Fibrillation	1976
The effects of practolol on the dysrhythmias complicating acute ischemic heart disease. The American journal of medicine, 1975, Volume: 58, Issue:2 Topics: Aged; Arrhythmias, Cardiac; Bradycardia; Coronary Disease; Electrocardiography; Female; Humans; Lido	1975
Analysis of components in a cardiogenic hypertensive chemoreflex. Circulation, 1975, Volume: 52, Issue:2 Topics: Animals; Atropine; Blood Pressure; Bradycardia; Cardiovascular System; Chemoreceptor Cells; Coronary	1975
Cardiac rhythm in men during cystoscopy. The Journal of urology, 1975, Volume: 113, Issue:6 Topics: Adult; Aged; Anesthesia, Epidural; Anesthesia, Inhalation; Arrhythmias, Cardiac; Bradycardia; Cystos	1975
[Treatment of arrhythmia in general practice]. Wiener medizinische Wochenschrift (1946), 1975, Nov-14, Volume: 125, Issue:46 Topics: Ajmaline; Anti-Arrhythmia Agents; Aprindine; Arrhythmia, Sinus; Arrhythmias, Cardiac; Bradycardia; H	1975
[Cardiac arrest and epidural anesthesia]. Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1992, Volume: 33, Issue:4 Topics: Anesthesia, Epidural; Bradycardia; Heart Arrest; Humans; Lidocaine; Male; Middle Aged	1992
Reduced left ventricular diameters at onset of bradycardia during epidural anaesthesia. Acta anaesthesiologica Scandinavica, 1992, Volume: 36, Issue:8 Topics: Adult; Aldosterone; Anesthesia, Epidural; Arginine Vasopressin; Blood Pressure; Bradycardia; Cardiac	1992
Differentiation of sinus rhythms from supraventricular tachydysrhythmias by activation sequence and timing. Pacing and clinical electrophysiology : PACE, 1990, Volume: 13, Issue:12 Pt 2 Topics: Animals; Atrial Fibrillation; Atrial Flutter; Atrial Function, Left; Atrioventricular Node; Bloodlet	1990
Arrhythmogenic activities of antiarrhythmic drugs in conscious hypokalemic dogs with atrioventricular block: comparison between quinidine, lidocaine, flecainide, propranolol and sotalol. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:2 Topics: Animals; Anti-Arrhythmia Agents; Bradycardia; Consciousness; Diuretics; Dogs; Electrocardiography, A	1991
[Therapy of acute myocardial infarct]. Deutsche medizinische Wochenschrift (1946), 1985, May-10, Volume: 110, Issue:19 Topics: Acidosis; Analgesics; Atropine; Bicarbonates; Bradycardia; Cardiac Complexes, Premature; Critical Ca	1985
QTU prolongation and polymorphic ventricular tachyarrhythmias due to bradycardia-dependent early afterdepolarizations. Afterdepolarizations and ventricular arrhythmias. Circulation research, 1988, Volume: 63, Issue:2 Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Bradycardia; Dogs; Intercellular Signaling Peptide	1988
Lidocaine skinwheal fails to prevent vasovagal reflex during venipuncture. The West Virginia medical journal, 1987, Volume: 83, Issue:6 Topics: Anesthesia, Local; Bradycardia; Humans; Hypotension; Lidocaine; Male; Middle Aged; Punctures; Reflex	1987
Precipitous bradycardia induced by laryngoscopy in cardiac surgical patients. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1987, Volume: 34, Issue:6 Topics: Aged; Anesthesia, General; Blood Gas Analysis; Bradycardia; Coronary Disease; Female; Humans; Laryng	1987
Cardiovascular toxicity of local anesthetics: an alternative hypothesis. Anesthesia and analgesia, 1986, Volume: 65, Issue:5 Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Bradycardia; Brain; Bupivacaine; Electric Stimulation	1986
[Cardiac rhythm disorders. 2. Therapy]. Medizinische Klinik, 1971, Apr-23, Volume: 66, Issue:17 Topics: Adrenergic alpha-Antagonists; Arrhythmia, Sinus; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial F	1971
[What is assured in the treatment of heart arrhythmia?]. Der Internist, 1972, Volume: 13, Issue:12 Topics: Adrenergic beta-Antagonists; Ajmaline; Atrial Fibrillation; Atrial Flutter; Atropine; Bradycardia; C	1972
Cardiac arrest in the coronary care unit. Australian and New Zealand journal of medicine, 1973, Volume: 3, Issue:4 Topics: Age Factors; Aged; Anti-Arrhythmia Agents; Bradycardia; Cardiac Complexes, Premature; Coronary Care	1973
[Comparison of aprindine (AC 1802) and lidocaine by intravenous route during the acute phase of myocardial infarct]. Acta cardiologica, 1974, Volume: Suppl 18 Topics: Aniline Compounds; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bradycardia; Cardiac Complexes, Pre	1974
[Arrhythmias in acute myocardial infarct]. Wiener Zeitschrift fur innere Medizin und ihre Grenzgebiete, 1973, Volume: 54, Issue:10 Topics: Acidosis; Acute Disease; Arrhythmias, Cardiac; Aspartic Acid; Atrial Fibrillation; Atrial Flutter; B	1973
[Therapy of arrhythmias]. Wiener Zeitschrift fur innere Medizin und ihre Grenzgebiete, 1973, Volume: 54, Issue:8-9 Topics: Ajmaline; Arrhythmias, Cardiac; Atrial Fibrillation; Bradycardia; Caffeine; Cardiac Complexes, Prema	1973
The value of intensive care. Transactions of the Medical Society of London, 1974, Volume: 90 Topics: Bradycardia; Cardiac Complexes, Premature; Coronary Care Units; Electric Countershock; Heart Atria;	1974
[Modern therapy of cardiac arrhythmias]. Schweizerische medizinische Wochenschrift, 1973, Feb-24, Volume: 103, Issue:8 Topics: Adrenergic beta-Antagonists; Ajmaline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atropine; Brady	1973
[Complications of regional anaesthesia and their treatment (author's transl)]. Munchener medizinische Wochenschrift (1950), 1973, Oct-12, Volume: 115, Issue:41 Topics: Adrenal Cortex Hormones; Anesthesia, Local; Apnea; Barbiturates; Bradycardia; Bupivacaine; Diagnosis	1973
[Symposium on anti-arrhythmic drugs of the Swedish Society of Cardiology]. Lakartidningen, 1973, Dec-12, Volume: 70, Issue:50 Topics: Adrenergic beta-Agonists; Ajmaline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bradycardia; Digit	1973
Cardiac output, heart rate, and blood pressure as influenced by equi-antiarrhythmic doses of eight antifibrillatory agents. Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1971, Volume: 271, Issue:4 Topics: Aconitum; Ajmaline; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Bradycard	1971
Cardiopulmonary resuscitation. II. American heart journal, 1969, Volume: 78, Issue:5 Topics: Acidosis; Aftercare; Bradycardia; Heart Arrest; Humans; Hyperkalemia; Hypokalemia; Isoproterenol; Li	1969
Effects of hexobarbitone, ether, morphine, and urethane upon the acute toxicity of propranolol and D-(--)-INPEA. The Journal of pharmacy and pharmacology, 1966, Volume: 18, Issue:10 Topics: Amino Alcohols; Animals; Atropine; Bradycardia; Central Nervous System; Drug Synergism; Ethers; Hear	1966
Management of arrhythmia. New York state journal of medicine, 1973, Jul-01, Volume: 73, Issue:13 Topics: Arrhythmias, Cardiac; Bradycardia; Electric Countershock; Humans; Lidocaine; Pacemaker, Artificial;	1973
Effect of lignocaine on heart rate in patients with sinus bradycardia associated with proven or suspected acute myocardial infarction. Cardiovascular research, 1972, Volume: 6, Issue:6 Topics: Adult; Aged; Angina Pectoris; Arrhythmias, Cardiac; Bradycardia; Electrocardiography; Female; Heart	1972
Treatment of nontraumatic cardiac emergencies. Postgraduate medicine, 1974, Volume: 55, Issue:1 Topics: Adams-Stokes Syndrome; Arrhythmias, Cardiac; Atropine; Bradycardia; Electric Countershock; Emergency	1974
Sinus bradycardia due to lidocaine: clinical-electrophysiologic correlations. Journal of electrocardiology, 1974, Volume: 7, Issue:1 Topics: Aged; Animals; Atropine; Bradycardia; Coronary Disease; Digoxin; Female; Heart Block; Heart Failure;	1974
Profound hypotension and bradycardia after a single bolus of lidocaine. Journal of electrocardiology, 1974, Volume: 7, Issue:1 Topics: Aged; Angina Pectoris; Arrhythmias, Cardiac; Atropine; Bradycardia; Coronary Disease; Humans; Hypote	1974
Paracervical block: advantages and disadvantages. Clinical obstetrics and gynecology, 1974, Volume: 17, Issue:2 Topics: Acidosis; Anesthesia, Obstetrical; Anesthetics, Local; Bradycardia; Cervix Uteri; Female; Fetal Dise	1974
Cardiovascular abnormalities following tricyclic antidepressant drug overdosage. Drugs, 1974, Volume: 7, Issue:5 Topics: Acidosis; Antidepressive Agents; Arrhythmias, Cardiac; Bicarbonates; Bradycardia; Heart Rate; Humans	1974
Observations during anesthesia for cardiac homotransplantation in ten patients. Anesthesiology, 1969, Volume: 30, Issue:2 Topics: Adolescent; Adult; Anesthesia, Inhalation; Atropine; Blood Pressure; Bradycardia; Calcium Chloride;	1969
The effects of continuous paracervical block, with one per cent lidocaine, on the fetal heart rate and uterine contractions. American journal of obstetrics and gynecology, 1972, Jan-01, Volume: 112, Issue:1 Topics: Adult; Anesthesia, Conduction; Bradycardia; Epinephrine; Female; Fetal Heart; Humans; Labor, Obstetr	1972
Investigations of the mode of action of a new antidysrhythmic drug, Kö 1173. British journal of pharmacology, 1972, Volume: 44, Issue:1 Topics: Action Potentials; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Anura; Bradycardia; Guinea P	1972
Cardiac arrhythmias in anesthesia and in acute myocardial infarction. International anesthesiology clinics, 1972,Spring, Volume: 10, Issue:1 Topics: Anesthesia; Arrhythmias, Cardiac; Atropine; Bradycardia; Digitalis Glycosides; Electrocardiography;	1972
Sinoatrial arrest due to lidocaine in a patient receiving guinidine. Chest, 1972, Volume: 61, Issue:7 Topics: Aged; Arrhythmias, Cardiac; Bradycardia; Dopamine; Drug Synergism; Electrocardiography; Heart Arrest	1972
[The effect of paracervical block on the fetus]. Der Anaesthesist, 1972, Volume: 21, Issue:3 Topics: Acidosis; Anesthesia, Conduction; Anesthesia, Obstetrical; Anesthetics, Local; Asphyxia Neonatorum;	1972
Intractable paroxysmal tachycardia in thyrotoxicosis simulating myocardial infarction. Acta medica Scandinavica, 1972, Volume: 192, Issue:5 Topics: Angina Pectoris; Atrial Fibrillation; Bradycardia; Cardiac Catheterization; Diagnosis, Differential;	1972
Fetal bradycardia after paracervical block. Obstetrics and gynecology, 1971, Volume: 38, Issue:4 Topics: Anesthesia, Conduction; Anesthesia, Obstetrical; Bradycardia; Catheterization; Cervix Uteri; Epineph	1971
[Arrhythmias. 6. Pacemaker treatment]. Lakartidningen, 1971, Jun-14, Volume: 68 Topics: Adams-Stokes Syndrome; Age Factors; Anesthetics; Arrhythmias, Cardiac; Bradycardia; Bretylium Compou	1971
Cardiac slowing, not cardiac irritability, the major problem in the prehospital phase of myocardial infarction. The Medical journal of Australia, 1971, Oct-09, Volume: 2, Issue:15 Topics: Atropine; Australia; Bradycardia; Coronary Care Units; Humans; Lidocaine; Myocardial Infarction; Sul	1971
Intracardiac route of the Bezold-Jarisch reflex. The American journal of physiology, 1971, Volume: 221, Issue:5 Topics: Animals; Bradycardia; Coronary Vessels; Dogs; Electrocardiography; Heart; Heart Block; Heart Conduct	1971
Treatment of arrhythmias associated with acute myocardial infarction. The Nebraska medical journal, 1971, Volume: 56, Issue:12 Topics: Arrhythmias, Cardiac; Atropine; Bradycardia; Digitalis Glycosides; Humans; Isoproterenol; Lidocaine;	1971
Carotid sinus reflex during radical neck dissection. Southern medical journal, 1969, Volume: 62, Issue:10 Topics: Adolescent; Adult; Age Factors; Aged; Atropine; Blood Pressure; Bradycardia; Carotid Sinus; Child; F	1969
[Drug therapy of arrhythmias]. Schweizerische medizinische Wochenschrift, 1969, Oct-25, Volume: 99, Issue:43 Topics: Adult; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Bradycardia; Female; Human	1969
[The effect of retrobulbar injection of xylocain on the oculo-cardiac reflex in operation for strabismus under inhalation anesthesia]. Nihon ganka kiyo, 1969, Volume: 20, Issue:8 Topics: Adolescent; Anesthesia, Inhalation; Bradycardia; Child; Child, Preschool; Electrocardiography; Eye;	1969
Bretylium tosylate in treatment of refractory ventricular arrhythmias complicating myocardial infarction. British heart journal, 1970, Volume: 32, Issue:1 Topics: Adult; Aged; Arrhythmias, Cardiac; Bradycardia; Bretylium Compounds; Electrocardiography; Female; Hu	1970
[Therapy of the most important cardiac arrhythmias]. Deutsche medizinische Wochenschrift (1946), 1970, Sep-04, Volume: 95, Issue:36 Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Bradycardia; Electric Countershock; Gluca	1970
Myocardial infarction and the G.P. British medical journal, 1970, Nov-07, Volume: 4, Issue:5731 Topics: Atropine; Bradycardia; Family Practice; First Aid; Humans; Lidocaine; Myocardial Infarction; Oxygen	1970
Fetal heart rate and pH of fetal capillary blood during epidural analgesia in labor. Obstetrics and gynecology, 1970, Volume: 36, Issue:6 Topics: Anesthesia, Obstetrical; Anesthesia, Spinal; Blood Pressure; Bradycardia; Capillaries; Female; Fetal	1970
[Treatment of the most severe postoperative cardiac arrhythmias]. Wiener Zeitschrift fur innere Medizin und ihre Grenzgebiete, 1970, Volume: 51, Issue:8 Topics: Aged; Arrhythmias, Cardiac; Bradycardia; Digitoxin; Electrocardiography; Female; Humans; Lidocaine;	1970
Emergency treatment of cardiac arrhythmias. Emphasis on use of electrical pacing. JAMA, 1970, Dec-14, Volume: 214, Issue:11 Topics: Arrhythmias, Cardiac; Atropine; Bradycardia; Electric Countershock; Electrocardiography; Electrodes;	1970
Fetal effects of spinal hypotension. Observations in the dog at term of pregnancy. Obstetrics and gynecology, 1971, Volume: 37, Issue:2 Topics: Anesthesia, Spinal; Animals; Blood Pressure; Bradycardia; Dogs; Female; Fetal Diseases; Fetal Heart;	1971
Cardiac arrhythmias. Pennsylvania medicine, 1971, Volume: 74, Issue:1 Topics: Anti-Arrhythmia Agents; Atropine; Bradycardia; Digitalis Glycosides; Electric Countershock; Humans;	1971
[Paracervical block in obstetrics]. L'union medicale du Canada, 1971, Volume: 100, Issue:8 Topics: Anesthesia, Local; Anesthesia, Obstetrical; Bradycardia; Cervix Uteri; Female; Fetal Diseases; Human	1971
Dysrhythmia and oral surgery. British journal of anaesthesia, 1971, Volume: 43, Issue:8 Topics: Adolescent; Adult; Age Factors; Aged; Anesthesia, General; Arrhythmias, Cardiac; Benperidol; Bradyca	1971
Atrial pacing to control heart rate and rhythm in acute cardiac conditions. Canadian Medical Association journal, 1971, May-22, Volume: 104, Issue:10 Topics: Acute Disease; Adult; Aged; Arrhythmias, Cardiac; Blood Volume; Bradycardia; Cardiac Catheterization	1971
Cardiac arrhythmias. I. British medical journal, 1971, May-22, Volume: 2, Issue:5759 Topics: Arrhythmias, Cardiac; Atropine; Bradycardia; Cardiac Catheterization; Heart Block; Humans; Lidocaine	1971
Cardiac arrhythmias. Recognition and management of emergencies. Postgraduate medicine, 1971, Volume: 49, Issue:5 Topics: Arrhythmias, Cardiac; Bradycardia; Digoxin; Electric Countershock; Electrocardiography; Humans; Isop	1971
Current trends in the care of the coronary patient. Geriatrics, 1968, Volume: 23, Issue:6 Topics: Anticoagulants; Arrhythmias, Cardiac; Bradycardia; Coronary Disease; Digitalis Glycosides; Diuretics	1968
Resuscitation from ventricular fibrillation. Drug therapy. JAMA, 1968, Jan-22, Volume: 203, Issue:4 Topics: Animals; Bicarbonates; Blood Pressure; Bradycardia; Carbon Dioxide; Dogs; Electric Countershock; Epi	1968
Treatment of arrhythmias in myocardial infarction. Archives of internal medicine, 1969, Volume: 124, Issue:1 Topics: Arrhythmias, Cardiac; Atropine; Bradycardia; Digitalis Glycosides; Electric Countershock; Electrocar	1969

lidocaine and Bradyarrhythmia