Page last updated: 2024-10-28

lidocaine and Bone Neoplasms

lidocaine has been researched along with Bone Neoplasms in 12 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Bone Neoplasms: Tumors or cancer located in bone tissue or specific BONES.

Research Excerpts

ExcerptRelevanceReference
"The aim of this study was to determine whether systemic administration of QX-314 reduces bone cancer pain through selective inhibition of transient receptor potential vanilloid subfamily 1 (TRPV1)-expressing afferents."7.83Systemic QX-314 Reduces Bone Cancer Pain through Selective Inhibition of Transient Receptor Potential Vanilloid Subfamily 1-expressing Primary Afferents in Mice. ( Fuseya, S; Kawamata, M; Kawamata, T; Minemura, H; Yamamoto, K; Yamaori, S, 2016)
" The results showed that the patients in the study group had low intraoperative bleeding, short operation time, low postoperative hematoma formation rate, high patient satisfaction, higher dosage of anesthetic solution, and low dosage of lidocaine."5.72Clinical Application of Artificial Intelligence: Auto-Discerning the Effectiveness of Lidocaine Concentration Levels in Osteosarcoma Femoral Tumor Segment Resection. ( Li, X; Ni, S; Yi, X, 2022)
"The aim of this study was to determine whether systemic administration of QX-314 reduces bone cancer pain through selective inhibition of transient receptor potential vanilloid subfamily 1 (TRPV1)-expressing afferents."3.83Systemic QX-314 Reduces Bone Cancer Pain through Selective Inhibition of Transient Receptor Potential Vanilloid Subfamily 1-expressing Primary Afferents in Mice. ( Fuseya, S; Kawamata, M; Kawamata, T; Minemura, H; Yamamoto, K; Yamaori, S, 2016)
"A controlled double-blind investigation was undertaken in which ten patients with painful bone metastases were treated with intravenous lignocaine in a dosage of 5 mg/kg body-weight infused over a period of 30 minutes or the same volume of isotonic saline."2.66[Intravenous lidocaine in the treatment of chronic pain caused by bone metastases]. ( Banning, AM; Gefke, K; Hebsgaard, K; Petersen, P; Sjøgren, P, 1989)
" The results showed that the patients in the study group had low intraoperative bleeding, short operation time, low postoperative hematoma formation rate, high patient satisfaction, higher dosage of anesthetic solution, and low dosage of lidocaine."1.72Clinical Application of Artificial Intelligence: Auto-Discerning the Effectiveness of Lidocaine Concentration Levels in Osteosarcoma Femoral Tumor Segment Resection. ( Li, X; Ni, S; Yi, X, 2022)
"Cancer-induced bone pain is described as dull, aching ongoing pain."1.42Behavioral and neurochemical analysis of ongoing bone cancer pain in rats. ( King, T; Navratilova, E; Okun, A; Porreca, F; Remeniuk, B; Sukhtankar, D; Xie, JY, 2015)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19902 (16.67)18.7374
1990's0 (0.00)18.2507
2000's3 (25.00)29.6817
2010's5 (41.67)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Ni, S1
Li, X1
Yi, X1
Mirshahidi, S1
Shields, TG1
de Necochea-Campion, R1
Yuan, X1
Janjua, A1
Williams, NL1
Mirshahidi, HR1
Reeves, ME1
Duerksen-Hughes, P1
Zuckerman, LM1
Remeniuk, B2
King, T2
Sukhtankar, D2
Nippert, A1
Li, N1
Li, F1
Cheng, K1
Rice, KC1
Porreca, F2
Berna, C1
Luthy, C1
Samer, CF1
Spechbach, H1
Pautex, S1
Piguet, V1
Okun, A1
Navratilova, E1
Xie, JY1
Fuseya, S1
Yamamoto, K1
Minemura, H1
Yamaori, S1
Kawamata, T1
Kawamata, M1
Buchanan, DD1
J MacIvor, F1
Rousseff, RT1
Simeonov, S1
Wilhelm, IR1
Griessinger, N1
Koppert, W1
Sittl, R1
Likar, R1
Colvin, L1
Fallon, M1
Zweig, JI1
Malspies, L1
Kaur, S1
Kabakow, B1
Sjøgren, P1
Banning, AM1
Hebsgaard, K1
Petersen, P1
Gefke, K1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Study of Perioperative Intravenous Infusion of Lidocaine on Postoperative Analgesia in Patients Undergoing Single-port Thoracoscopic[NCT04043624]Phase 480 participants (Anticipated)Interventional2019-08-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for lidocaine and Bone Neoplasms

ArticleYear
[Intravenous lidocaine in the treatment of chronic pain caused by bone metastases].
    Ugeskrift for laeger, 1989, Aug-21, Volume: 151, Issue:34

    Topics: Adult; Aged; Bone Neoplasms; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Infusion

1989

Other Studies

11 other studies available for lidocaine and Bone Neoplasms

ArticleYear
Clinical Application of Artificial Intelligence: Auto-Discerning the Effectiveness of Lidocaine Concentration Levels in Osteosarcoma Femoral Tumor Segment Resection.
    Journal of healthcare engineering, 2022, Volume: 2022

    Topics: Adolescent; Artificial Intelligence; Bone Neoplasms; Child; Femoral Neoplasms; Femur; Humans; Lidoca

2022
Bupivacaine and Lidocaine Induce Apoptosis in Osteosarcoma Tumor Cells.
    Clinical orthopaedics and related research, 2021, 01-01, Volume: 479, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Bone Neoplasms; Bupivacain

2021
Disease modifying actions of interleukin-6 blockade in a rat model of bone cancer pain.
    Pain, 2018, Volume: 159, Issue:4

    Topics: Adenocarcinoma; Analgesics; Analysis of Variance; Anesthetics, Local; Animals; Bone Neoplasms; Bufan

2018
[Efficient treatment of breakthrough pain in adults: the importance of timing and medication choice].
    Revue medicale suisse, 2013, Jun-26, Volume: 9, Issue:392

    Topics: Administration, Cutaneous; Aged; Analgesics; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammato

2013
Behavioral and neurochemical analysis of ongoing bone cancer pain in rats.
    Pain, 2015, Volume: 156, Issue:10

    Topics: Adenocarcinoma; Analgesics, Opioid; Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Stero

2015
Systemic QX-314 Reduces Bone Cancer Pain through Selective Inhibition of Transient Receptor Potential Vanilloid Subfamily 1-expressing Primary Afferents in Mice.
    Anesthesiology, 2016, Volume: 125, Issue:1

    Topics: Anesthetics, Local; Animals; Behavior, Animal; Bone Neoplasms; Cyclic AMP Response Element-Binding P

2016
A role for intravenous lidocaine in severe cancer-related neuropathic pain at the end-of-life.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2010, Volume: 18, Issue:7

    Topics: Aged; Anesthetics, Local; Back Pain; Bone Neoplasms; Humans; Infusions, Intravenous; Kidney Neoplasm

2010
Intralesional treatment in painful rib metastases.
    Palliative medicine, 2004, Volume: 18, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anti-Inflammatory Agents; Bone Neoplasms; Humans

2004
High doses of topically applied lidocaine in a cancer patient.
    Journal of pain and symptom management, 2005, Volume: 30, Issue:3

    Topics: Administration, Topical; Anesthetics, Local; Bone Neoplasms; Humans; Lidocaine; Osteosarcoma; Pain;

2005
Challenges in cancer pain management--bone pain.
    European journal of cancer (Oxford, England : 1990), 2008, Volume: 44, Issue:8

    Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Bone Density Conservation Agents; Bone Diseases

2008
A novel approach to the temporary control of intractable bone pain.
    JAMA, 1980, Nov-28, Volume: 244, Issue:21

    Topics: Bone Neoplasms; Drug Therapy, Combination; Humans; Injections; Lidocaine; Pain, Intractable; Penicil

1980