Page last updated: 2024-10-28

lidocaine and Body Weight

lidocaine has been researched along with Body Weight in 73 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
"To determine the median effective dose (ED50) of prophylactic intravenous lidocaine for the prevention of propofol medium-chain triglyceride/long-chain triglyceride (MCT/LCT) emulsion injection pain."9.41Median Effective Dose of Lidocaine for the Prevention of Pain Caused by the Injection of Propofol Formulated with Medium- and Long-Chain Triglycerides Based on Lean Body Weight. ( Ma, R; Shan, Q; Sui, W; Tan, C; Tian, S; Xing, Z; Zhang, D; Zhang, Z; Zhou, W, 2021)
" The objectives of this study were to assess the effects of intraperitoneal (IP) ketamine (95 mg/kg) and xylazine (7 mg/kg) alone or combined with lidocaine at 4, 8, or 16 mg/kg on time to loss (LRR) and return (RRR) of righting reflex, duration of immobilization and loss of pedal withdrawal response (PWR), body weight and histopathology in CD-1 mice."7.85Anesthetic effects and body weight changes associated with ketamine-xylazine-lidocaine administered to CD-1 mice. ( Clark-Price, SC; Dholakia, U; Keating, SCJ; Stern, AW, 2017)
"To evaluate age-dependent changes in lidocaine disposition in patients with acute myocardial infarction, we measured plasma concentrations of lidocaine and its metabolites monoethylglycinexylidide and glycinexylidide after discontinuation of a maintenance lidocaine infusion."7.67Age-dependent lidocaine disposition in patients with acute myocardial infarction. ( Cusson, J; Lawand, S; Matthews, C; Nattel, S; Talajic, M, 1985)
"To determine the median effective dose (ED50) of prophylactic intravenous lidocaine for the prevention of propofol medium-chain triglyceride/long-chain triglyceride (MCT/LCT) emulsion injection pain."5.41Median Effective Dose of Lidocaine for the Prevention of Pain Caused by the Injection of Propofol Formulated with Medium- and Long-Chain Triglycerides Based on Lean Body Weight. ( Ma, R; Shan, Q; Sui, W; Tan, C; Tian, S; Xing, Z; Zhang, D; Zhang, Z; Zhou, W, 2021)
"1 mL of 2% or 10% lidocaine hydrochloride solution (treatments L2 and L10, respectively) sprayed on the larynx for laryngeal desensitization, followed by endotracheal intubation and isoflurane anesthesia."3.88Plasma concentrations of lidocaine following laryngeal administration or laryngeal and intratesticular administration in cats. ( Soltaninejad, H; Vesal, N, 2018)
" The objectives of this study were to assess the effects of intraperitoneal (IP) ketamine (95 mg/kg) and xylazine (7 mg/kg) alone or combined with lidocaine at 4, 8, or 16 mg/kg on time to loss (LRR) and return (RRR) of righting reflex, duration of immobilization and loss of pedal withdrawal response (PWR), body weight and histopathology in CD-1 mice."3.85Anesthetic effects and body weight changes associated with ketamine-xylazine-lidocaine administered to CD-1 mice. ( Clark-Price, SC; Dholakia, U; Keating, SCJ; Stern, AW, 2017)
"To evaluate age-dependent changes in lidocaine disposition in patients with acute myocardial infarction, we measured plasma concentrations of lidocaine and its metabolites monoethylglycinexylidide and glycinexylidide after discontinuation of a maintenance lidocaine infusion."3.67Age-dependent lidocaine disposition in patients with acute myocardial infarction. ( Cusson, J; Lawand, S; Matthews, C; Nattel, S; Talajic, M, 1985)
"The clinical use and toxicity of intravenous lidocaine were surveyed in 750 hospitalized medical patients who received the drug for the treatment of cardiac arrhythmias."3.65Clinical use and toxicity of intravenous lidocaine. A report from the Boston Collaborative Drug Surveillance Program. ( Greenblatt, DJ; Koch-Weser, J; Pfeifer, HJ, 1976)
" Ongoing safety evaluation and research is warranted since this is the first known report in the literature describing implementation of a weight-based dosing SOP."2.80Pain management prior to nasogastric tube placement: atomized lidocaine. ( Bruene, D; Farrington, M; Wagner, M, 2015)
" The final pharmacokinetic parameters were V(1)(L) = 0."2.76Population pharmacokinetics of lidocaine administered during and after cardiac surgery. ( Hsu, YW; Mathew, JP; Newman, MF; Somma, J, 2011)
" Thus the suggested usual upper limit for dosage for a healthy adult patient is four and a half 2 ml (or 2."2.39Evidence for safety margins of lignocaine local anaesthetics for peri-oral use. ( Cannell, H, 1996)
" The measured peak plasma concentration of lidocaine or prilocaine did not reach toxic levels in any patient."1.31The efficacy and safety of EMLA cream for awake fiberoptic endotracheal intubation. ( Afshar, M; Cypel, D; Goldberg, ME; Gratz, I; Larijani, GE; Mandel, R; Mroz, L, 2000)
"Lidocaine disposition was modified during head-down tilt: a significant decrease in maximal concentration (1."1.29Impact of a four-day head-down tilt (-6 degrees) on lidocaine pharmacokinetics used as probe to evaluate hepatic blood flow. ( Cornac, A; Güell, A; Houin, G; Pavy-Le Traon, A; Saivin, S, 1995)
"Lidocaine was administered using a 5% lidocaine spray."1.29Lidocaine plasma concentrations in pediatric patients after providing airway topical anesthesia from a calibrated device. ( Autret, E; Furet, P; Laffon, M; Lesage, V; Mercier, C; Sitbon, P, 1996)
"Lidocaine metabolism was studied in livers isolated from animals 7 d after treatment."1.29Effects of light-exposed parenteral nutrition on hepatic function and lidocaine metabolism: a study using isolated rat liver perfusion. ( Coutts, RT; Jewell, LD; Tam, YK; Zaman, N, 1996)
"Sensitivity and specificity were 50% and 97%, respectively."1.29Factors associated with hypotension and bradycardia after epidural blockade. ( Curatolo, M; Orlando, A; Scaramozzino, P; Venuti, FS; Zbinden, AM, 1996)
"Ethanol pretreatment and body weight had no effect on MEGX levels at any of the time points tested in this model."1.28Effects of controlled liver injury and ethanol pretreatment on monoethylglycine xylidide formation in the rat. ( Druckenbrod, RW; Mendenhall, CL; Myre, SA; Schroeder, TJ; Stanberry, EA, 1991)
"Lidocaine dosage recommendations vary widely."1.27Optimum dosage of lidocaine. ( Arstila, M; Kanto, J; Laurikainen, E; Pekkarinen, A, 1985)
"Lidocaine toxicity was life-threatening or significantly complicated the management of 15 patients."1.26Excessive serum lidocaine levels during maintenance infusions: mechanisms and prevention. ( Atkinson, AJ; Davison, R; Parker, M, 1982)
" Dosage can be calculated on this basis for operations on the perineum, lower and groin with 97 to 98% confidence."1.26Caudal analgesia in children. Five hundred cases for procedures below the diaphragm. ( McGown, RG, 1982)
"The first seizure activity observed was tonic extension (TE) which occurred at an infused lidocaine dose of 12."1.26Cardiorespiratory and behavioral reactions to the lidocaine-induced convulsions in the dog. ( Gangarosa, LP; Hofman, WF; Jerram, DC, 1977)

Research

Studies (73)

TimeframeStudies, this research(%)All Research%
pre-199034 (46.58)18.7374
1990's18 (24.66)18.2507
2000's11 (15.07)29.6817
2010's8 (10.96)24.3611
2020's2 (2.74)2.80

Authors

AuthorsStudies
Toner, AJ1
Bailey, MA1
Schug, SA1
Phillips, M1
Ungerer, JP1
Somogyi, AA1
Corcoran, TB1
Tian, S1
Zhang, D1
Zhou, W1
Tan, C1
Shan, Q1
Ma, R1
Xing, Z1
Sui, W1
Zhang, Z1
Dholakia, U1
Clark-Price, SC1
Keating, SCJ1
Stern, AW1
Mortazaei, S1
Sahraei, H1
Bahari, Z1
Meftahi, GH1
Pirzad Jahromi, G1
Hatef, B1
Soltaninejad, H1
Vesal, N1
Hofmann, K1
Rauh, A1
Harlizius, J1
Weiß, C1
Scholz, T1
Schulze-Horsel, T1
Escribano, D1
Ritzmann, M1
Zöls, S1
Wang, Z1
Shen, L1
Li, X1
Shu, X1
Shan, B1
Zhang, L1
Gong, Y1
Dong, Z1
Farrington, M1
Bruene, D1
Wagner, M1
Chou, YC1
Cheng, YS1
Hsu, YH1
Yu, YH1
Liu, SJ1
Shafqat, K1
Pal, SK1
Kumari, S1
Kyriacou, PA1
Hsu, YW1
Somma, J1
Newman, MF1
Mathew, JP1
Stafford, KJ1
Mellor, DJ1
Todd, SE1
Bruce, RA1
Ward, RN1
Lefrant, JY1
Muller, L1
de La Coussaye, JE1
Lalourcey, L1
Ripart, J1
Peray, PA1
Mazoit, X1
Dauzat, M1
Sassine, A1
Eledjam, JJ1
Azma, T1
Kawai, K1
Tamura, H1
Okada, K1
Okida, M1
Gawronska-Szklarz, B1
Musial, HD1
Loniewski, I1
Paprota, B1
Drozdzik, M1
Weaver, JM2
Mellema, SC1
Doherr, MG1
Wechsler, B1
Thüer, S1
Steiner, A1
Kelly, DA1
Henderson, AM1
Davison, R1
Parker, M1
Atkinson, AJ1
McGown, RG1
Axelsson, K1
Widman, B1
Bloedow, DC1
Ralston, DH1
Hargrove, JC1
Curatolo, M2
Orlando, A2
Zbinden, AM2
Scaramozzino, P2
Venuti, FS2
Saivin, S1
Pavy-Le Traon, A1
Cornac, A1
Güell, A1
Houin, G1
Thalhammer, JG1
Vladimirova, M1
Bershadsky, B1
Strichartz, GR1
Muir, JK1
Lyeth, BG1
Hamm, RJ2
Ellis, EF2
Kim, Y1
Sitbon, P1
Laffon, M1
Lesage, V1
Furet, P1
Autret, E1
Mercier, C1
Zaman, N2
Tam, YK2
Jewell, LD2
Coutts, RT2
Temple, MD1
Pike, BR1
Preshaw, PM1
Rowson, JE1
Cannell, H1
Barat, SA1
Turkall, RM1
Milman, N1
Laub, M1
Munch, EP1
Angelo, HR1
Meechan, J1
Larijani, GE1
Cypel, D1
Gratz, I1
Mroz, L1
Mandel, R1
Afshar, M1
Goldberg, ME1
Hocking, G1
Balmer, HG1
Lei, B1
Cottrell, JE1
Kass, IS1
Trkulja, V1
Lackovic, Z1
Hofman, WF1
Jerram, DC1
Gangarosa, LP1
Baheti, DK1
Britt, BA1
Endrenyi, L1
Cadman, DL1
Fan, HM1
Fung, HY1
Gilbert, RM1
Auad Juri, A1
Abouleish, E1
Donck, AV1
Meeuwis, H1
Taylor, F1
Pfeifer, HJ1
Greenblatt, DJ1
Koch-Weser, J1
Vuorinen, I1
Heinonen, J1
Rosenberg, P1
Lekieffre, J1
Thery, C1
Ginestet, A1
Carré, A1
Warembourg, H1
Covino, BG1
Bush, DF1
Curran, J1
Hamilton, C1
Taylor, T1
Hunt, CM1
Westerkam, WR1
Stave, GM1
Druckenbrod, RW1
Mendenhall, CL1
Myre, SA1
Stanberry, EA1
Schroeder, TJ1
Teiling, AK1
Mohammed, AK1
Minor, BG1
Järbe, TU1
Hiltunen, AJ1
Archer, T1
Cusson, J1
Nattel, S1
Matthews, C1
Talajic, M1
Lawand, S1
Laurikainen, E1
Arstila, M1
Pekkarinen, A1
Kanto, J1
Shaw, TR1
Kumana, CR1
Royds, RB1
Padgham, CM1
Hamer, J1
Fazekas, A1
Bódi, K1
Scott, DB2
Jebson, PJ1
Braid, DP2
Ortengren, B1
Frisch, P1
Kerstein, MD1
Bergentz, SE1
Lewis, DH1
Munson, ES1
Wagman, IH1
Dure-Smith, P1
Freundlich, IM1
Hara, Y1
Takahashi, M1
Petry, EL1
Lurie, PR1
Kirkpatrick, SE1
Stanton, RE1
Schulte-Steinberg, O1
Rahlfs, VW1
Fox, GS1
Houle, GL1
Desjardins, PD1
Mercier, G1
Morada, AO1
Levin, P1
Fonkalsrud, EW1

Reviews

1 review available for lidocaine and Body Weight

ArticleYear
Evidence for safety margins of lignocaine local anaesthetics for peri-oral use.
    British dental journal, 1996, Oct-05, Volume: 181, Issue:7

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Body Weight; Child; Dental Care for Chronically Ill;

1996

Trials

10 trials available for lidocaine and Body Weight

ArticleYear
Serum lidocaine (lignocaine) concentrations during prolonged perioperative infusion in patients undergoing breast cancer surgery: A secondary analysis of a randomised controlled trial.
    Anaesthesia and intensive care, 2023, Volume: 51, Issue:6

    Topics: Anesthetics, Local; Body Weight; Breast Neoplasms; Double-Blind Method; Female; Humans; Infusions, I

2023
Median Effective Dose of Lidocaine for the Prevention of Pain Caused by the Injection of Propofol Formulated with Medium- and Long-Chain Triglycerides Based on Lean Body Weight.
    Pain medicine (Malden, Mass.), 2021, 06-04, Volume: 22, Issue:6

    Topics: Anesthetics, Intravenous; Anesthetics, Local; Body Weight; Double-Blind Method; Humans; Lidocaine; P

2021
Pain management prior to nasogastric tube placement: atomized lidocaine.
    ORL-head and neck nursing : official journal of the Society of Otorhinolaryngology and Head-Neck Nurses, 2015,Winter, Volume: 33, Issue:1

    Topics: Administration, Intranasal; Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Body Wei

2015
Population pharmacokinetics of lidocaine administered during and after cardiac surgery.
    Journal of cardiothoracic and vascular anesthesia, 2011, Volume: 25, Issue:6

    Topics: Aged; Algorithms; Anesthetics, Local; Body Weight; Cardiac Surgical Procedures; Cardiopulmonary Bypa

2011
Effects of local anaesthesia or local anaesthesia plus a non-steroidal anti-inflammatory drug on the acute cortisol response of calves to five different methods of castration.
    Research in veterinary science, 2002, Volume: 73, Issue:1

    Topics: Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Cattle; Hydrocort

2002
Comparative benefit of preemptively applied thiopental for propofol injection pain: the advantage over lidocaine.
    Hiroshima journal of medical sciences, 2004, Volume: 53, Issue:1

    Topics: Adult; Aged; Anesthetics, Intravenous; Anesthetics, Local; Body Weight; Dose-Response Relationship,

2004
A single sub-anaesthetic dose of propofol to reduce patient recall of peribulbar block.
    Journal of the Royal Army Medical Corps, 2000, Volume: 146, Issue:3

    Topics: Age Factors; Aged; Anesthetics, Intravenous; Anesthetics, Local; Body Weight; Bupivacaine; Cataract

2000
[Personal experience with over 3,500 cases of epidural block].
    Revista espanola de anestesiologia y reanimacion, 1977, Volume: 24, Issue:4

    Topics: Adolescent; Adult; Anesthesia, Epidural; Body Weight; Bupivacaine; Child; Clinical Trials as Topic;

1977
Effect of anaesthesia for delivery on the weight of infants during the first 5 days of life.
    British journal of anaesthesia, 1978, Volume: 50, Issue:6

    Topics: Anesthesia, Epidural; Anesthesia, General; Anesthesia, Obstetrical; Anesthesia, Spinal; Birth Weight

1978
Topical analgesia before tracheal intubation.
    Anaesthesia, 1975, Volume: 30, Issue:6

    Topics: Administration, Topical; Anesthesia, Local; Body Weight; Humans; Intubation, Intratracheal; Larynx;

1975

Other Studies

62 other studies available for lidocaine and Body Weight

ArticleYear
Anesthetic effects and body weight changes associated with ketamine-xylazine-lidocaine administered to CD-1 mice.
    PloS one, 2017, Volume: 12, Issue:9

    Topics: Anesthesia; Animals; Body Weight; Dose-Response Relationship, Drug; Drug Administration Schedule; In

2017
Ventral tegmental area inactivation alters hormonal, metabolic, and locomotor responses to inescapable stress.
    Archives of physiology and biochemistry, 2019, Volume: 125, Issue:4

    Topics: Adrenal Glands; Animals; Anorexia; Body Weight; Corticosterone; Drinking; Immobilization; Lidocaine;

2019
Plasma concentrations of lidocaine following laryngeal administration or laryngeal and intratesticular administration in cats.
    American journal of veterinary research, 2018, Volume: 79, Issue:6

    Topics: Anesthesia; Anesthetics, Local; Animals; Body Weight; Cats; Isoflurane; Larynx; Lidocaine; Male; Orc

2018
[Pain and distress responses of suckling piglets to injection and castration under local anaesthesia with procaine and lidocaine - Part 1: Cortisol, chromogranin A, wound healing, weights, losses].
    Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere, 2019, Volume: 47, Issue:2

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Animals, Suckling; Body Weight; Chromogranin A; Hand

2019
Pain‑relieving effect of a compound isolated from white peony root oral liquid on acute radiation‑induced esophagitis.
    Molecular medicine reports, 2013, Volume: 7, Issue:6

    Topics: Administration, Oral; Anesthetics, Local; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents;

2013
Biodegradable nanofiber-membrane for sustainable release of lidocaine at the femoral fracture site as a periosteal block: In vitro and in vivo studies in a rabbit model.
    Colloids and surfaces. B, Biointerfaces, 2016, Apr-01, Volume: 140

    Topics: Absorbable Implants; Anesthetics, Local; Animals; Body Weight; Delayed-Action Preparations; Drinking

2016
Time-frequency analysis of HRV data from locally anesthetized patients.
    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2009, Volume: 2009

    Topics: Adult; Aged; Anesthetics, Local; Body Height; Body Weight; Bupivacaine; Elective Surgical Procedures

2009
Hemodynamic and cardiac electrophysiologic effects of lidocaine-bupivacaine mixture in anesthetized and ventilated piglets.
    Anesthesiology, 2003, Volume: 98, Issue:1

    Topics: Anesthesia; Anesthetics, Local; Animals; Body Weight; Bupivacaine; Drug Combinations; Electrocardiog

2003
Lidocaine metabolism in isolated perfused liver from streptozotocin-induced diabetic rats.
    The Journal of pharmacy and pharmacology, 2006, Volume: 58, Issue:8

    Topics: Anesthetics, Local; Animals; Body Weight; Diabetes Mellitus, Experimental; In Vitro Techniques; Lido

2006
Calculating the maximum recommended dose of local anesthetic.
    Journal of the California Dental Association, 2007, Volume: 35, Issue:1

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Body Weight; Bupivacaine; Child; Drug Interactions; D

2007
[Influence of local anaesthesia on pain and distress induced by bloodless castration methods in young lambs].
    Schweizer Archiv fur Tierheilkunde, 2007, Volume: 149, Issue:5

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Animals, Newborn; Behavior, Animal; Body Weight; Han

2007
Use of local anesthetic drugs in hospital practice.
    British medical journal (Clinical research ed.), 1983, Jun-04, Volume: 286, Issue:6380

    Topics: Anesthetics, Local; Body Weight; Humans; Lidocaine

1983
Local anaesthetic drugs in hospital practice.
    British medical journal (Clinical research ed.), 1983, Jul-30, Volume: 287, Issue:6388

    Topics: Adult; Anesthetics, Local; Body Weight; Drug Administration Schedule; Humans; Lidocaine; Safety

1983
Excessive serum lidocaine levels during maintenance infusions: mechanisms and prevention.
    American heart journal, 1982, Volume: 104, Issue:2 Pt 1

    Topics: Aged; Arrhythmias, Cardiac; Body Weight; Chromatography, Gas; Disease Susceptibility; Heart Arrest;

1982
Caudal analgesia in children. Five hundred cases for procedures below the diaphragm.
    Anaesthesia, 1982, Volume: 37, Issue:8

    Topics: Anesthesia, Caudal; Anesthesia, Epidural; Body Weight; Bupivacaine; Child; Child, Preschool; Epineph

1982
Blood concentration of lidocaine after spinal anaesthesia using lidocaine and lidocaine with adrenaline.
    Acta anaesthesiologica Scandinavica, 1981, Volume: 25, Issue:3

    Topics: Aged; Anesthesia, Spinal; Blood Pressure; Body Height; Body Surface Area; Body Weight; Epinephrine;

1981
Lidocaine pharmacokinetics in pregnant and nonpregnant sheep.
    Journal of pharmaceutical sciences, 1980, Volume: 69, Issue:1

    Topics: Animals; Body Weight; Cardiac Output; Female; Kinetics; Lidocaine; Liver; Pregnancy; Pregnancy, Anim

1980
A multifactorial analysis to explain inadequate surgical analgesia after extradural block.
    British journal of anaesthesia, 1995, Volume: 75, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, Epidural; Anesthetics,

1995
Impact of a four-day head-down tilt (-6 degrees) on lidocaine pharmacokinetics used as probe to evaluate hepatic blood flow.
    Journal of clinical pharmacology, 1995, Volume: 35, Issue:7

    Topics: Adult; Anti-Arrhythmia Agents; Blood Flow Velocity; Body Weight; Cardiac Output; Head-Down Tilt; Hum

1995
Neurologic evaluation of the rat during sciatic nerve block with lidocaine.
    Anesthesiology, 1995, Volume: 82, Issue:4

    Topics: Animals; Behavior, Animal; Body Weight; Evaluation Studies as Topic; Gait; Heating; Hindlimb; Lidoca

1995
The effect of acute cocaine or lidocaine on behavioral function following fluid percussion brain injury in rats.
    Journal of neurotrauma, 1995, Volume: 12, Issue:1

    Topics: Animals; Behavior, Animal; Body Weight; Brain Injuries; Cocaine; Lidocaine; Male; Maze Learning; Mot

1995
Interaction between beta blockers and epinephrine on hemodynamics of spontaneously hypertensive rats.
    Research communications in chemical pathology and pharmacology, 1993, Volume: 80, Issue:1

    Topics: Acebutolol; Adult; Animals; Body Weight; Drug Interactions; Epinephrine; Female; Hemodynamics; Human

1993
Lidocaine plasma concentrations in pediatric patients after providing airway topical anesthesia from a calibrated device.
    Anesthesia and analgesia, 1996, Volume: 82, Issue:5

    Topics: Aerosols; Anesthesia, Inhalation; Anesthesia, Local; Anesthetics, Inhalation; Anesthetics, Local; Bo

1996
Effects of light-exposed parenteral nutrition on hepatic function and lidocaine metabolism: a study using isolated rat liver perfusion.
    Pediatric research, 1996, Volume: 40, Issue:2

    Topics: Amino Acids; Animals; Body Weight; In Vitro Techniques; Lidocaine; Light; Liver; Male; Organ Size; O

1996
The effect of postinjury administration of polyethylene glycol-conjugated superoxide dismutase (pegorgotein, Dismutec) or lidocaine on behavioral function following fluid-percussion brain injury in rats.
    Journal of neurotrauma, 1996, Volume: 13, Issue:6

    Topics: Anesthetics, Local; Animals; Antioxidants; Behavior, Animal; Body Weight; Brain Injuries; Lidocaine;

1996
Factors associated with hypotension and bradycardia after epidural blockade.
    Anesthesia and analgesia, 1996, Volume: 83, Issue:5

    Topics: Adjuvants, Anesthesia; Adult; Aged; Analgesia, Epidural; Anesthesia, Epidural; Anesthetics, Local; B

1996
The use of lignocaine local anaesthetic.
    British dental journal, 1996, Oct-05, Volume: 181, Issue:7

    Topics: Adult; Aged; Anesthesia, Dental; Anesthetics, Local; Body Weight; Child; Female; Health Knowledge, A

1996
Effect of sub-chronic cocaine and lidocaine exposure on the lymphoid tissues in neonatal rats.
    Toxicology letters, 1996, Dec-31, Volume: 89, Issue:3

    Topics: Animals; Animals, Newborn; Body Weight; Cocaine; Female; Immunoglobulin M; Leukocytes; Lidocaine; Ly

1996
Effects of intravenous lipid as a source of energy in parenteral nutrition associated hepatic dysfunction and lidocaine elimination: a study using isolated rat liver perfusion.
    Biopharmaceutics & drug disposition, 1997, Volume: 18, Issue:9

    Topics: Amino Acids; Animals; Biomarkers; Body Weight; Chromatography, High Pressure Liquid; Disease Models,

1997
Serum concentrations of lignocaine and its metabolite monoethylglycinexylidide during fibre-optic bronchoscopy in local anaesthesia.
    Respiratory medicine, 1998, Volume: 92, Issue:1

    Topics: Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Area Under Curve; Body Weight; Bronc

1998
How to avoid local anaesthetic toxicity.
    British dental journal, 1998, Apr-11, Volume: 184, Issue:7

    Topics: Adult; Aged; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Body Weight; Child; Child, P

1998
The efficacy and safety of EMLA cream for awake fiberoptic endotracheal intubation.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:4

    Topics: Adult; Anesthetics, Combined; Anesthetics, Local; Body Weight; Female; Fiber Optic Technology; Gaggi

2000
Neuroprotective effect of low-dose lidocaine in a rat model of transient focal cerebral ischemia.
    Anesthesiology, 2001, Volume: 95, Issue:2

    Topics: Anesthetics, Local; Animals; Blood Gas Analysis; Body Weight; Brain Infarction; Brain Ischemia; Hemo

2001
Vagal influence on compensatory ovarian growth is important only briefly after hemicastration.
    Experimental biology and medicine (Maywood, N.J.), 2001, Volume: 226, Issue:8

    Topics: Animals; Body Weight; Cyclic AMP; Female; Lidocaine; Organ Size; Ovariectomy; Ovary; Rats; Rats, Wis

2001
Articaine, a new local anesthetic for American dentists: will it supersede lidocaine?
    Anesthesia progress, 1999,Fall, Volume: 46, Issue:4

    Topics: Adult; Anesthetics, Local; Body Weight; Carticaine; Child; Drug Approval; Humans; Lidocaine; Safety;

1999
Cardiorespiratory and behavioral reactions to the lidocaine-induced convulsions in the dog.
    Research communications in chemical pathology and pharmacology, 1977, Volume: 16, Issue:4

    Topics: Animals; Blood Pressure; Body Temperature; Body Weight; Carbon Dioxide; Dogs; Female; Heart Rate; He

1977
Epidural analgesia with left lateral tilt for Caesarean section.
    Anaesthesia, 1975, Volume: 30, Issue:3

    Topics: Adult; Anesthesia, Epidural; Apgar Score; Back Pain; Blood Pressure; Body Weight; Cesarean Section;

1975
Porcine malignant hyperthermia: effects of halothane on mitochondrial respiration and calcium accumulation.
    Anesthesiology, 1975, Volume: 42, Issue:3

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Analysis of Variance; Animals; Body Weight; Calcium;

1975
A further failure to replicate an effect of oral anesthesia on alcohol consumption by rats.
    Journal of studies on alcohol, 1975, Volume: 36, Issue:5

    Topics: Administration, Oral; Alcohol Drinking; Animals; Body Weight; Choice Behavior; Decision Making; Food

1975
Pharmacokinetics of lidocaine.
    JAMA, 1977, Apr-04, Volume: 237, Issue:14

    Topics: Arrhythmias, Cardiac; Body Weight; Humans; Injections, Intravenous; Lidocaine

1977
Clinical use and toxicity of intravenous lidocaine. A report from the Boston Collaborative Drug Surveillance Program.
    American heart journal, 1976, Volume: 92, Issue:2

    Topics: Aged; Arrhythmias, Cardiac; Body Weight; Female; Heart Failure; Hospitalization; Humans; Infusions,

1976
The effect of ethanol on the duration of toxic action of lidocaine: an experimental study on rats and mice.
    Acta pharmacologica et toxicologica, 1976, Volume: 38, Issue:1

    Topics: Animals; Body Temperature; Body Weight; Drug Interactions; Ethanol; Female; Lidocaine; Liver; Mice;

1976
[LETTER: Lidocaine per os. Its value in ventricular rhythm disorders].
    La Nouvelle presse medicale, 1975, Jan-18, Volume: 4, Issue:3

    Topics: Administration, Oral; Arrhythmias, Cardiac; Body Weight; Drug Tolerance; Heart Ventricles; Humans; L

1975
Clinical evaluation of local anaesthetic agents.
    British journal of anaesthesia, 1975, Volume: 47 suppl

    Topics: Age Factors; Analgesia; Anesthesia, Conduction; Anesthesia, Epidural; Anesthetics, Local; Body Weigh

1975
Effect of age and gender on the activity of human hepatic CYP3A.
    Biochemical pharmacology, 1992, Jul-22, Volume: 44, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aging; Alcohol Drinking; Aryl Hydrocarbon Hydroxylases; Body Weight;

1992
Effects of controlled liver injury and ethanol pretreatment on monoethylglycine xylidide formation in the rat.
    Pharmacology, 1991, Volume: 42, Issue:3

    Topics: Animals; Body Weight; Caffeine; Diet; Ethanol; Half-Life; Hepatectomy; Indocyanine Green; Lidocaine;

1991
Lack of effects of prenatal exposure to lidocaine on development of behavior in rats.
    Anesthesia and analgesia, 1987, Volume: 66, Issue:6

    Topics: Animals; Avoidance Learning; Behavior, Animal; Body Weight; Conditioning, Classical; Discrimination

1987
Age-dependent lidocaine disposition in patients with acute myocardial infarction.
    Clinical pharmacology and therapeutics, 1985, Volume: 37, Issue:4

    Topics: Adult; Age Factors; Aged; Body Weight; Chromatography, High Pressure Liquid; Female; Heart Failure;

1985
Optimum dosage of lidocaine.
    International journal of clinical pharmacology, therapy, and toxicology, 1985, Volume: 23, Issue:1

    Topics: Aged; Body Weight; Female; Heart Failure; Humans; Lidocaine; Male; Middle Aged; Myocardial Infarctio

1985
Use of plasma levels in evaluation of procainamide dosage.
    British heart journal, 1974, Volume: 36, Issue:3

    Topics: Administration, Oral; Adult; Aged; Arrhythmias, Cardiac; Body Weight; Cardiac Complexes, Premature;

1974
[General effect of adrenalin in dental anesthesia].
    Fogorvosi szemle, 1974, Volume: 67, Issue:7

    Topics: Anesthesia, Dental; Anesthesia, Local; Body Weight; Epinephrine; Humans; Lidocaine; Receptors, Adren

1974
Factors affecting plasma levels of lignocaine and prilocaine.
    British journal of anaesthesia, 1972, Volume: 44, Issue:10

    Topics: Abdomen; Adult; Age Factors; Aged; Anesthesia, Epidural; Anesthesia, Local; Body Weight; Capillaries

1972
The clearance of red blood cells from the cadaver kidney.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1970, Volume: 2, Issue:4

    Topics: Animals; Body Weight; Cadaver; Chromium Radioisotopes; Dextrans; Edema; Erythrocytes; Female; Hepari

1970
Acid-base changes during lidocaine induced seizures in Macaca mulatta.
    Archives of neurology, 1969, Volume: 20, Issue:4

    Topics: Acid-Base Equilibrium; Amygdala; Animals; Behavior, Animal; Body Weight; Caudate Nucleus; Electroenc

1969
Bronchography: the rational use of premedication and local anesthesia.
    Journal of the Canadian Association of Radiologists, 1971, Volume: 22, Issue:3

    Topics: Anesthetics, Local; Atropine; Body Weight; Bronchography; Bronchoscopy; Cocaine; Codeine; Cough; Dib

1971
[Clinical and experimental studies of the relationship between the nasal region and the sex organ. 1. Vaginal discharge and histological change of the ovary and the uterus in the rat. Effects on uterine contraction in humans].
    Nihon Jibiinkoka Gakkai kaiho, 1970, Volume: 73, Issue:5

    Topics: Anesthesia, Obstetrical; Animals; Body Weight; Cautery; Female; Humans; Labor, Obstetric; Lidocaine;

1970
Percutaneous heart catheterization in infants and children. I. Catheter placement and manipulation with guide wires.
    Circulation, 1970, Volume: 42, Issue:6

    Topics: Adolescent; Age Factors; Anesthesia, Local; Angiography; Body Weight; Cardiac Catheterization; Child

1970
Caudal anaesthesia in children and spread of 1 per cent lignocaine. A statistical study.
    British journal of anaesthesia, 1970, Volume: 42, Issue:12

    Topics: Age Factors; Anesthesia, Spinal; Body Height; Body Weight; Child; Child, Preschool; Humans; Infant;

1970
Intrauterine fetal lidocaine concentrations during continuous epidural anesthesia.
    American journal of obstetrics and gynecology, 1971, Aug-01, Volume: 110, Issue:7

    Topics: Anesthesia, Conduction; Anesthesia, Epidural; Anesthesia, Obstetrical; Body Weight; Chromatography,

1971
Postmortem pulmonary edema. Differential susceptibility in newborn and adult rabbits.
    Archives of pathology, 1968, Volume: 85, Issue:5

    Topics: Age Factors; Animals; Animals, Newborn; Body Weight; Drug Synergism; Heart; Hypoxia; Lidocaine; Lung

1968
Fecal continence following colectomy and ileoanal anastomosis through extramucosal rectal tube.
    The Journal of surgical research, 1968, Volume: 8, Issue:5

    Topics: Anal Canal; Animals; Body Weight; Colectomy; Colitis, Ulcerative; Defecation; Dogs; Epinephrine; Hum

1968
Dosage of lignocaine in epidural block in relation to toxicity.
    British journal of anaesthesia, 1966, Volume: 38, Issue:8

    Topics: Adult; Aged; Anesthesia, Spinal; Body Weight; Epinephrine; Female; Humans; Lidocaine; Middle Aged

1966