lidocaine has been researched along with Bladder Cancer in 42 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study aimed to investigate whether lidocaine, alone or in combination with other chemotherapeutic agents, inhibits the growth of human bladder cancer cells in vitro and orthotopically transplanted bladder tumors in vivo." | 7.88 | Lidocaine enhances the effects of chemotherapeutic drugs against bladder cancer. ( Li, M; Mi, Z; Ren, L; Xu, J; Yan, L; Yang, X; Zhang, S; Zhao, L, 2018) |
| "This study aimed to investigate whether lidocaine, alone or in combination with other chemotherapeutic agents, inhibits the growth of human bladder cancer cells in vitro and orthotopically transplanted bladder tumors in vivo." | 3.88 | Lidocaine enhances the effects of chemotherapeutic drugs against bladder cancer. ( Li, M; Mi, Z; Ren, L; Xu, J; Yan, L; Yang, X; Zhang, S; Zhao, L, 2018) |
| "Transurethral resection of bladder tumors (TURBT) surgeries requires post-resection catheterization for continuous irrigation of the bladder." | 3.30 | Transurethral lidocaine (100 mg) bladder irrigation (TULI100) reduces the incidence of catheter related bladder discomfort in transurethral resection of bladder tumors: A randomized, double blind, controlled trial. ( Bora, GS; Ganesh, V; Kaloria, N; Kayina, CA; Kumar, S; Naik, N; Pandey, VK; Saini, K; Saini, V; Samra, T; Singh, A; Soni, SL, 2023) |
| "Lidocaine 2% 15 mL was administered for anesthesia." | 2.70 | The median approach to transsacral epidural block. ( Hanaoka, K; Nishiyama, T; Ochiai, Y, 2002) |
| "Pain was assessed using a linear analogue scale from 0 to 10." | 2.70 | Photodynamic therapy for superficial bladder cancer under local anaesthetic. ( Betts, CD; Briggs, C; Clarke, NW; Gilhooley, A; Moore, JV; O'Flynn, KJ; Shackley, DC; Whitehurst, C, 2002) |
| "An accurate assessment of the risk of a bladder cancer can be obtained with NMP22, cytology, and cystoscopy in patients with a history of bladder cancer." | 2.69 | Clinical application of NMP22 in the management of transitional cell carcinoma of the bladder. ( Bagiella, E; Sawczuk, AT; Sawczuk, IS; Yun, EJ, 2000) |
| "Patients with unilateral urinary bladder tumors were randomized to receive direct obturator nerve block with 15 ml of lidocaine (Group A, n = 20), while those with bilateral tumors received a bilateral direct obturator nerve block with 30 ml (2 x 15 ml) of lidocaine (Group B, n = 12)." | 2.68 | Lidocaine plasma levels following two techniques of obturator nerve block. ( Atanassoff, PG; Brull, SJ; Weiss, BM, 1996) |
| "The BCAN (Bladder Cancer Advocacy Network) Patient Survey Network identified pain during intravesical procedures as a research priority for patients." | 2.61 | Reduction of Pain during Flexible Cystoscopy: A Systematic Review and Meta-Analysis. ( Ball, AL; Brown, B; Gore, JL; Holt, SK; Lipman, R; Lotan, Y; Raskolnikov, D; Schroeck, F; Smith, AB; Strope, S; Ullman, R, 2019) |
| "Lidocaine or heat treatment of T24 cells during sonication enhanced luciferase expression significantly." | 1.32 | Ultrasound mediated intravesical transfection enhanced by treatment with lidocaine or heat. ( Feril, LB; Fuse, H; Kagiya, G; Kondo, T; Nakaya, N; Nozaki, T; Ogawa, R, 2004) |
| "Significant impairment of BCG viability, dependent on dosage and time of co-incubation, was noted with all lubricants analyzed." | 1.29 | The effect of lubricants on viability of bacillus Calmette-Guerin for intravesical immunotherapy against bladder carcinoma. ( Böhle, A; Braasch, H; Jocham, D; Rüsch-Gerdes, S; Ulmer, AJ, 1996) |
| "Sedoanalgesia is a technique developed to provide safe and satisfactory operating conditions for a wide range of patients independent of age and overall level of fitness (although its use in children remains to be established)." | 1.28 | Sedoanalgesia in urology: a safe, cost-effective alternative to general anaesthesia. A review of 1020 cases. ( Anson, KM; Birch, BR; Miller, RA, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (19.05) | 18.7374 |
| 1990's | 12 (28.57) | 18.2507 |
| 2000's | 10 (23.81) | 29.6817 |
| 2010's | 6 (14.29) | 24.3611 |
| 2020's | 6 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Cazenave, L | 1 |
| Faucher, M | 1 |
| Tourret, M | 1 |
| Marques, M | 1 |
| Tezier, M | 1 |
| Mokart, D | 1 |
| Singh, A | 1 |
| Kayina, CA | 1 |
| Naik, N | 1 |
| Ganesh, V | 1 |
| Kumar, S | 1 |
| Pandey, VK | 1 |
| Bora, GS | 1 |
| Saini, K | 1 |
| Soni, SL | 1 |
| Kaloria, N | 1 |
| Samra, T | 1 |
| Saini, V | 1 |
| Moeen, AM | 1 |
| Kim, DH | 1 |
| Park, JY | 1 |
| Yu, J | 1 |
| Lee, SA | 1 |
| Park, S | 1 |
| Hwang, JH | 1 |
| Koh, GH | 1 |
| Kim, YK | 1 |
| Ströck, V | 1 |
| Holmäng, S | 4 |
| Zhu, H | 1 |
| Li, Q | 1 |
| Liao, T | 1 |
| Yin, X | 1 |
| Chen, Q | 1 |
| Wang, Z | 1 |
| Dai, M | 1 |
| Yi, L | 1 |
| Ge, S | 1 |
| Miao, C | 1 |
| Zeng, W | 1 |
| Qu, L | 1 |
| Ju, Z | 1 |
| Huang, G | 1 |
| Cang, C | 1 |
| Xiong, W | 1 |
| Yang, X | 1 |
| Zhao, L | 1 |
| Li, M | 1 |
| Yan, L | 1 |
| Zhang, S | 1 |
| Mi, Z | 1 |
| Ren, L | 1 |
| Xu, J | 1 |
| Raskolnikov, D | 1 |
| Brown, B | 1 |
| Holt, SK | 1 |
| Ball, AL | 1 |
| Lotan, Y | 1 |
| Strope, S | 1 |
| Schroeck, F | 1 |
| Ullman, R | 1 |
| Lipman, R | 1 |
| Smith, AB | 1 |
| Gore, JL | 1 |
| Erbay, G | 1 |
| Akyol, F | 1 |
| Karabakan, M | 1 |
| Celebi, B | 1 |
| Keskin, E | 1 |
| Hirik, E | 1 |
| Lee, SJ | 1 |
| Bai, SJ | 1 |
| Lee, JS | 1 |
| Kim, WO | 1 |
| Shin, YS | 1 |
| Lee, KY | 1 |
| Losco, G | 1 |
| Antoniou, S | 1 |
| Mark, S | 1 |
| Khorrami, M | 1 |
| Hadi, M | 1 |
| Javid, A | 1 |
| Izadpahani, MH | 1 |
| Mohammadi Sichani, M | 1 |
| Zargham, M | 1 |
| Alizadeh, F | 1 |
| Zhang, J | 1 |
| Zheng, YY | 1 |
| Feng, ZY | 1 |
| Chen, CQ | 1 |
| Zhu, SM | 1 |
| Nishiyama, T | 1 |
| Hanaoka, K | 1 |
| Ochiai, Y | 1 |
| PRENTISS, RJ | 1 |
| HARVEY, GW | 1 |
| BETHARD, WF | 1 |
| BOATWRIGHT, DE | 1 |
| PENNINGTON, RD | 1 |
| Ogawa, R | 1 |
| Kagiya, G | 1 |
| Feril, LB | 1 |
| Nakaya, N | 1 |
| Nozaki, T | 1 |
| Fuse, H | 1 |
| Kondo, T | 1 |
| Fassoulaki, A | 2 |
| Melemeni, A | 1 |
| Zotou, M | 2 |
| Sarantopoulos, C | 2 |
| Fujiwara, Y | 1 |
| Sato, Y | 1 |
| Kitayama, M | 1 |
| Shibata, Y | 1 |
| Komatsu, T | 1 |
| Hirota, K | 1 |
| Chitale, S | 1 |
| Hirani, M | 1 |
| Swift, L | 1 |
| Ho, E | 1 |
| Vogler, H | 1 |
| Augspurger, RR | 1 |
| Donohue, RE | 1 |
| Aldenborg, F | 2 |
| Hedelin, H | 3 |
| Böhle, A | 1 |
| Rüsch-Gerdes, S | 1 |
| Ulmer, AJ | 1 |
| Braasch, H | 1 |
| Jocham, D | 1 |
| Bovianska, N | 1 |
| Amano, T | 1 |
| Ohkawa, M | 1 |
| Kunimi, K | 1 |
| Oshinoya, Y | 1 |
| Uchibayashi, T | 1 |
| Atanassoff, PG | 1 |
| Weiss, BM | 1 |
| Brull, SJ | 1 |
| Wiman, L | 1 |
| Fredman, B | 1 |
| Zohar, E | 1 |
| Philipov, A | 1 |
| Olsfanger, D | 1 |
| Shalev, M | 1 |
| Jedeikin, R | 1 |
| Karabinis, G | 1 |
| Sawczuk, IS | 1 |
| Bagiella, E | 1 |
| Sawczuk, AT | 1 |
| Yun, EJ | 1 |
| Dryhurst, DJ | 1 |
| Fowler, CG | 1 |
| Herr, HW | 1 |
| Schneider, M | 1 |
| Shackley, DC | 1 |
| Briggs, C | 1 |
| Gilhooley, A | 1 |
| Whitehurst, C | 1 |
| O'Flynn, KJ | 1 |
| Betts, CD | 1 |
| Moore, JV | 1 |
| Clarke, NW | 1 |
| Pode, D | 1 |
| Zylber-Katz, E | 1 |
| Shapiro, A | 1 |
| Fujita, Y | 1 |
| Kimura, K | 1 |
| Furukawa, Y | 1 |
| Takaori, M | 1 |
| Birch, BR | 1 |
| Anson, KM | 1 |
| Miller, RA | 1 |
| Kristensen, J | 1 |
| Helbo-Hansen, HS | 1 |
| Toft, P | 1 |
| Hole, P | 1 |
| Shumleva, V | 1 |
| Minkov, N | 1 |
| Gotsev, G | 1 |
| Pironkov, A | 1 |
| Kleinman, B | 1 |
| Belusko, R | 1 |
| Wandschneider, G | 1 |
| Creevy, CD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Addition of Lidocaine to Levobupivacaine Reduces Intrathecal Block Duration: Randomized Controlled Trial[NCT01675895] | Phase 4 | 40 participants (Actual) | Interventional | 2009-07-31 | Completed | ||
| A Comparison of the Recovery Profiles of Bupivacaine or Bupivacaine Mixed With Lidocaine Spinal Anesthesia and Local Infiltration Anesthesia for Outpatient Herniorrhaphy[NCT01548794] | Phase 4 | 93 participants (Actual) | Interventional | 2012-03-31 | Completed | ||
| Phase 2 Study of Diclofenac Suppository to Control Pain During Flexible Cystoscopy[NCT01812928] | Phase 2 | 60 participants (Actual) | Interventional | 2013-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for lidocaine and Bladder Cancer
| Article | Year |
|---|---|
Reduction of Pain during Flexible Cystoscopy: A Systematic Review and Meta-Analysis.
Topics: Anesthetics, Local; Cystoscopy; Humans; Lidocaine; Male; Pain Management; Pain Measurement; Randomiz | 2019 |
18 trials available for lidocaine and Bladder Cancer
| Article | Year |
|---|---|
Transurethral lidocaine (100 mg) bladder irrigation (TULI100) reduces the incidence of catheter related bladder discomfort in transurethral resection of bladder tumors: A randomized, double blind, controlled trial.
Topics: Adult; Humans; Incidence; Lidocaine; Pain, Postoperative; Saline Solution; Transurethral Resection o | 2023 |
Editorial Comment on Transurethral lidocaine (100 mg) bladder irrigation (TULI100) reduces the incidence of catheter-related bladder discomfort in TURBT: A randomized, double-blind, controlled trial.
Topics: Humans; Incidence; Lidocaine; Urinary Bladder; Urinary Bladder Neoplasms; Urinary Catheterization; U | 2023 |
Intravenous Lidocaine for the Prevention of Postoperative Catheter-Related Bladder Discomfort in Male Patients Undergoing Transurethral Resection of Bladder Tumors: A Randomized, Double-Blind, Controlled Trial.
Topics: Administration, Intravenous; Aged; Anesthetics, Local; Double-Blind Method; Humans; Lidocaine; Male; | 2020 |
The duration of intrathecal bupivacaine mixed with lidocaine.
Topics: Aged; Anesthetics, Local; Bupivacaine; Double-Blind Method; Drug Synergism; Female; Humans; Injectio | 2008 |
The duration of intrathecal bupivacaine mixed with lidocaine.
Topics: Aged; Anesthetics, Local; Bupivacaine; Double-Blind Method; Drug Synergism; Female; Humans; Injectio | 2008 |
The duration of intrathecal bupivacaine mixed with lidocaine.
Topics: Aged; Anesthetics, Local; Bupivacaine; Double-Blind Method; Drug Synergism; Female; Humans; Injectio | 2008 |
The duration of intrathecal bupivacaine mixed with lidocaine.
Topics: Aged; Anesthetics, Local; Bupivacaine; Double-Blind Method; Drug Synergism; Female; Humans; Injectio | 2008 |
Male flexible cystoscopy: does waiting after insertion of topical anaesthetic lubricant improve patient comfort?
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Chlorhexidine; Cystosco | 2011 |
A comparison between blind and nerve stimulation guided obturator nerve block in transurethral resection of bladder tumor.
Topics: Anesthetics, Local; Cystectomy; Electric Stimulation Therapy; Female; Humans; Injections; Intraopera | 2012 |
Epidural fentanyl decreases the minimum local analgesic concentration of epidural lidocaine.
Topics: Adult; Analgesia, Epidural; Drug Interactions; Female; Fentanyl; Fistula; Hemorrhoidectomy; Humans; | 2012 |
The median approach to transsacral epidural block.
Topics: Aged; Anesthesia, Epidural; Anesthetics, Local; Epidural Space; Hemodynamics; Humans; Lidocaine; Mal | 2002 |
Systemic ondansetron antagonizes the sensory block produced by intrathecal lidocaine.
Topics: Aged; Anesthetics, Local; Antiemetics; Double-Blind Method; Female; Humans; Injections, Spinal; Lido | 2005 |
Prospective randomized crossover trial of lubricant gel against an anaesthetic gel for outpatient cystoscopy.
Topics: Administration, Topical; Aged; Aged, 80 and over; Ambulatory Care; Analgesics; Anesthesia, Local; Ch | 2008 |
Topical anaesthesia for bladder biopsies and cautery: intravesical lidocaine versus caudal anaesthesia.
Topics: Administration, Intravesical; Aged; Aged, 80 and over; Anesthesia, Caudal; Anesthesia, Local; Anesth | 1995 |
Lidocaine plasma levels following two techniques of obturator nerve block.
Topics: Absorption; Adrenergic Agonists; Adult; Aged; Analysis of Variance; Anesthetics, Local; Epinephrine; | 1996 |
The induction, maintenance, and recovery characteristics of spinal versus general anesthesia in elderly patients.
Topics: Aged; Aged, 80 and over; Anesthesia Recovery Period; Anesthesia, General; Anesthesia, Spinal; Anesth | 1998 |
Assessment of the level of sensory block after subarachnoid anesthesia using a pressure palpator.
Topics: Aged; Anesthesia, Spinal; Anesthetics, Local; Cross-Over Studies; Humans; Lidocaine; Male; Needles; | 1999 |
Clinical application of NMP22 in the management of transitional cell carcinoma of the bladder.
Topics: Aged; Anesthetics, Local; Bayes Theorem; Biomarkers, Tumor; Carcinoma, Transitional Cell; Conscious | 2000 |
Immediate versus delayed outpatient flexible cystoscopy: final report of a randomized study.
Topics: Aged; Aged, 80 and over; Anesthetics, Local; Cystoscopy; Follow-Up Studies; Gels; Humans; Lidocaine; | 2001 |
Photodynamic therapy for superficial bladder cancer under local anaesthetic.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Anesthesia, Local; Anesthetics, Local; Carcinoma, Tran | 2002 |
Spinal anaesthesia with glucose-free 2% lignocaine. Effect of different volumes.
Topics: Aged; Anesthesia, Spinal; Blood Pressure; Clinical Trials as Topic; Female; Glucose; Heart Rate; Hum | 1989 |
23 other studies available for lidocaine and Bladder Cancer
| Article | Year |
|---|---|
Intravenous lidocaine and cancer outcomes after radical cystectomy.
Topics: Administration, Intravenous; Cystectomy; Humans; Lidocaine; Retrospective Studies; Treatment Outcome | 2022 |
Is bladder tumour fulguration under local anaesthesia more painful than cystoscopy only?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Biopsy; Cystoscop | 2020 |
Metabolomic profiling of single enlarged lysosomes.
Topics: Amino Acid Transport Systems; Amino Acid Transport Systems, Basic; Cellular Senescence; Fibroblasts; | 2021 |
Lidocaine enhances the effects of chemotherapeutic drugs against bladder cancer.
Topics: Administration, Intravesical; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; | 2018 |
Effect of obturator nerve block during transurethral resection of lateral bladder wall tumors on the presence of detrusor muscle in tumor specimens and recurrence of the disease.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Spinal; Anesthetics, Local; Carcinoma in Situ; Female; H | 2017 |
MASSIVE ADDUCTOR MUSCLE CONTRACTION IN TRANSURETHRAL SURGERY: CAUSE AND PREVENTION; DEVELOPMENT OF ELECTRICAL CIRCUITRY.
Topics: Anesthesia; Anesthesia, Local; Anesthesia, Spinal; Diathermy; Dogs; Drug Therapy; Electrophysiology; | 1965 |
Ultrasound mediated intravesical transfection enhanced by treatment with lidocaine or heat.
Topics: Animals; Cell Line, Tumor; Cell Membrane; Cell Survival; Female; Gene Expression; Gene Transfer Tech | 2004 |
Obturator nerve block using ultrasound guidance.
Topics: Anesthetics, Local; Femoral Vein; Humans; Lidocaine; Muscle, Skeletal; Nerve Block; Obturator Nerve; | 2007 |
[Study of the disinfectant action of lubricants in transurethral electroresection].
Topics: Anti-Infective Agents, Urinary; Bacterial Infections; Chlorhexidine; Drug Combinations; Electrosurge | 1980 |
Prevention of obturator nerve stimulation during transurethral surgery.
Topics: Anesthesia, Spinal; Humans; Lidocaine; Male; Nerve Block; Obturator Nerve; Urethra; Urinary Bladder | 1980 |
Multiple bladder biopsies under intravesical lignocaine anaesthesia.
Topics: Aged; Aged, 80 and over; Biopsy, Needle; Female; Humans; Lidocaine; Male; Middle Aged; Pain; Patient | 1994 |
Extirpation and fulguration of multiple superficial bladder tumour recurrences under intravesical lignocaine anaesthesia.
Topics: Administration, Intravesical; Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anti-Bacterial Agen | 1994 |
The effect of lubricants on viability of bacillus Calmette-Guerin for intravesical immunotherapy against bladder carcinoma.
Topics: Adjuvants, Immunologic; Administration, Intravesical; Anesthetics, Local; BCG Vaccine; Carcinoma in | 1996 |
[Combined spinal and epidural analgesia in urology].
Topics: Adult; Aged; Analgesia, Epidural; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Carcinoma; Fe | 1995 |
[Outpatient treatment of bladder cancer--lower cost and satisfied patients].
Topics: Ambulatory Surgical Procedures; Anesthetics, Local; Cost Control; Costs and Cost Analysis; Cystoscop | 1997 |
Flexible cystodiathermy can be rendered painless by using 2% lignocaine solution to provide intravesical anaesthesia.
Topics: Administration, Intravesical; Anesthetics, Local; Chlorhexidine; Cystoscopy; Diathermy; Drug Combina | 2001 |
Intravesical lidocaine: topical anesthesia for bladder mucosal biopsies.
Topics: Administration, Intravesical; Aged; Aged, 80 and over; Anesthesia, Local; Biopsy; Carcinoma in Situ; | 1992 |
Plasma concentrations of lignocaine after obturator nerve block combined with spinal anaesthesia in patients undergoing transurethral resection procedures.
Topics: Aged; Aged, 80 and over; Anesthesia, Spinal; Humans; Lidocaine; Male; Middle Aged; Nerve Block; Obtu | 1992 |
Sedoanalgesia in urology: a safe, cost-effective alternative to general anaesthesia. A review of 1020 cases.
Topics: Ambulatory Surgical Procedures; Anesthesia, Local; Biopsy; Cystoscopy; Humans; Lidocaine; Male; Mida | 1990 |
[Obturator nerve block together with peridural anesthesia for analgesia in transurethral resection of tumors of the urinary bladder].
Topics: Aged; Anesthesia, Epidural; Female; Humans; Lidocaine; Male; Middle Aged; Nerve Block; Urinary Bladd | 1987 |
Delayed cephalad spread of a lidocaine spinal anesthetic causing ventilatory failure.
Topics: Anesthesia Recovery Period; Anesthesia, Spinal; Dyspnea; Female; Humans; Lidocaine; Middle Aged; Pos | 1986 |
[On the question of the infiltration anesthesia in operations on the bladder].
Topics: Anesthesia, Local; Electrosurgery; Humans; Injections; Lidocaine; Methods; Papilloma; Procaine; Ther | 1967 |
Preventing stimulation of the obturator nerve during transurethral resection.
Topics: Anesthesia, Local; Electric Stimulation; Electrosurgery; Epinephrine; Humans; Lidocaine; Male; Metho | 1968 |