Page last updated: 2024-10-28

lidocaine and Bladder, Overactive

lidocaine has been researched along with Bladder, Overactive in 15 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Research Excerpts

ExcerptRelevanceReference
"Intravesical instillation of TRG-100 was found to be safe and efficient in reducing pain and irritative bladder symptoms in our study population."5.91Open Label, Pilot Evaluation of the Safety and Efficacy of Intravesical Sustained Release System of Lidocaine and Oxybutynin (TRG-100) for Patients With Interstitial Cystitis/Bladder Pain Syndrome, Overactive Bladder and Patients With Retained Ureteral St ( Ala-Adin, N; Chertin, B; Dothan, D; Gordon, A; Hatumi, S; Kafka, I; Malchi, N; Moldwin, R; Nassar, T; Perez, D; Raisin, G; Shenfeld, O; Touitou, D, 2023)
"To compare pain scores with preprocedure oral phenazopyridine vs intravesical lidocaine in women undergoing intradetrusor onabotulinumtoxinA injections for idiopathic overactive bladder."5.51Oral phenazopyridine vs intravesical lidocaine for bladder onabotulinumtoxinA analgesia: a randomized controlled trial. ( Jacobs, KM; Raker, CA; Siddique, M; Stewart, LE; Sung, VW, 2022)
"Patients suffering from urge syndrome with and without urge incontinence and non-responding to oral anticholinergic drugs underwent EMDA therapy (2000 mg lidocaine-HCl 4% (50 ml), 2 mg epinephrine [1:1000] (2 ml), 40 mg dexamethason-21-dihydrogen phosphat (10 ml) in a total volume of 100 ml)."3.75Electromotive drug-administration: a pilot study for minimal-invasive treatment of therapy-resistant idiopathic detrusor overactivity. ( Bach, P; Goepel, M; Möhring, C; Wormland, RT, 2009)
"Sedation-free intradetrusor botulinum toxin-A injection using intravesical lidocaine and flexible endoscopy is a well tolerated and safe procedure to perform in an office setting."2.73Safety and tolerability of sedation-free flexible cystoscopy for intradetrusor botulinum toxin-A injection. ( Barboglio, P; Cohen, BL; Gousse, A; Rivera, R, 2007)
"The treatment of patients with overactive bladder (OAB) refractory to conventional treatment is gaining clinical significance."2.47[Therapy-refractory overactive bladder: alternative treatment approaches]. ( Hamann, M; Jünemann, KP; Knüpfer, S; Melchior, D; Naumann, CM, 2011)
"Intravesical instillation of TRG-100 was found to be safe and efficient in reducing pain and irritative bladder symptoms in our study population."1.91Open Label, Pilot Evaluation of the Safety and Efficacy of Intravesical Sustained Release System of Lidocaine and Oxybutynin (TRG-100) for Patients With Interstitial Cystitis/Bladder Pain Syndrome, Overactive Bladder and Patients With Retained Ureteral St ( Ala-Adin, N; Chertin, B; Dothan, D; Gordon, A; Hatumi, S; Kafka, I; Malchi, N; Moldwin, R; Nassar, T; Perez, D; Raisin, G; Shenfeld, O; Touitou, D, 2023)
"Lidocaine is a common local anesthetic and antiarrhythmic drug that acts via the local anesthetic effect of blocking voltage-gated sodium channels in peripheral neurons."1.56Effects of 1% Lidocaine Instillation on Overactive Bladder Induced by Bladder Outlet Obstruction in Rats. ( Han, SW; Kang, HJ; Kim, JH; Kim, SW; Lee, YS, 2020)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (40.00)29.6817
2010's5 (33.33)24.3611
2020's4 (26.67)2.80

Authors

AuthorsStudies
Stewart, LE1
Siddique, M1
Jacobs, KM1
Raker, CA1
Sung, VW1
Faure Walker, N3
Macpherson, F3
Tasleem, A3
Rampal, T3
Raisin, G1
Dothan, D1
Perez, D1
Ala-Adin, N1
Kafka, I1
Shenfeld, O1
Hatumi, S1
Malchi, N1
Gordon, A1
Touitou, D1
Moldwin, R1
Nassar, T1
Chertin, B1
Kang, HJ1
Kim, SW1
Lee, YS1
Han, SW1
Kim, JH1
Hermieu, JF1
Ballanger, P1
Amarenco, G1
Chartier-Kastler, E1
Cosson, M1
Costa, P1
Fatton, B1
Deffieux, X1
Denys, P1
Gamé, X1
Haab, F1
Karsenty, G1
Le Normand, L1
Ruffion, A1
Saussine, C1
Tamam, Y1
Özdemir, HH1
Gedik, A1
Tamam, C1
Nazlıkul, H1
Mitra, R1
Huang, L1
Payne, C1
Bach, P1
Wormland, RT1
Möhring, C1
Goepel, M1
Juszczak, K2
Ziomber, A1
Wyczolkowski, M1
Thor, PJ2
Knüpfer, S1
Hamann, M1
Naumann, CM1
Melchior, D1
Jünemann, KP1
Furuta, A1
Suzuki, Y1
Honda, M1
Koike, Y1
Naruoka, T1
Asano, K1
Chancellor, M1
Egawa, S1
Yoshimura, N1
Cohen, BL1
Rivera, R1
Barboglio, P1
Gousse, A1
Roxburgh, C2
Cook, J2
Dublin, N2

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Oral Phenazopyridine Versus Intravesical Lidocaine for Office OnabotulinumtoxinA Analgesia: A Randomized Controlled Trial[NCT03755089]Phase 4110 participants (Anticipated)Interventional2018-11-01Recruiting
Effectiveness of HYPNOsis Masks in the Management of Pain and Anxiety During Botulinum TOXin Injections in the Treatment of Idiopathic Overactive Bladder: a Multicenter Randomized Parallel Group Study.[NCT05352945]70 participants (Anticipated)Interventional2022-06-30Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for lidocaine and Bladder, Overactive

ArticleYear
Interventions to improve tolerability of local anesthetic intradetrusor Botulinum toxin injections: A systematic review.
    Neurourology and urodynamics, 2023, Volume: 42, Issue:1

    Topics: Administration, Intravesical; Anesthetics, Local; Botulinum Toxins, Type A; Humans; Lidocaine; Neuro

2023
Interventions to improve tolerability of local anesthetic intradetrusor Botulinum toxin injections: A systematic review.
    Neurourology and urodynamics, 2023, Volume: 42, Issue:1

    Topics: Administration, Intravesical; Anesthetics, Local; Botulinum Toxins, Type A; Humans; Lidocaine; Neuro

2023
Interventions to improve tolerability of local anesthetic intradetrusor Botulinum toxin injections: A systematic review.
    Neurourology and urodynamics, 2023, Volume: 42, Issue:1

    Topics: Administration, Intravesical; Anesthetics, Local; Botulinum Toxins, Type A; Humans; Lidocaine; Neuro

2023
Interventions to improve tolerability of local anesthetic intradetrusor Botulinum toxin injections: A systematic review.
    Neurourology and urodynamics, 2023, Volume: 42, Issue:1

    Topics: Administration, Intravesical; Anesthetics, Local; Botulinum Toxins, Type A; Humans; Lidocaine; Neuro

2023
Interventions to improve tolerability of local anesthetic intradetrusor Botulinum toxin injections: A systematic review.
    Neurourology and urodynamics, 2023, Volume: 42, Issue:1

    Topics: Administration, Intravesical; Anesthetics, Local; Botulinum Toxins, Type A; Humans; Lidocaine; Neuro

2023
Interventions to improve tolerability of local anesthetic intradetrusor Botulinum toxin injections: A systematic review.
    Neurourology and urodynamics, 2023, Volume: 42, Issue:1

    Topics: Administration, Intravesical; Anesthetics, Local; Botulinum Toxins, Type A; Humans; Lidocaine; Neuro

2023
Interventions to improve tolerability of local anesthetic intradetrusor Botulinum toxin injections: A systematic review.
    Neurourology and urodynamics, 2023, Volume: 42, Issue:1

    Topics: Administration, Intravesical; Anesthetics, Local; Botulinum Toxins, Type A; Humans; Lidocaine; Neuro

2023
Interventions to improve tolerability of local anesthetic intradetrusor Botulinum toxin injections: A systematic review.
    Neurourology and urodynamics, 2023, Volume: 42, Issue:1

    Topics: Administration, Intravesical; Anesthetics, Local; Botulinum Toxins, Type A; Humans; Lidocaine; Neuro

2023
Interventions to improve tolerability of local anesthetic intradetrusor Botulinum toxin injections: A systematic review.
    Neurourology and urodynamics, 2023, Volume: 42, Issue:1

    Topics: Administration, Intravesical; Anesthetics, Local; Botulinum Toxins, Type A; Humans; Lidocaine; Neuro

2023
[Therapy-refractory overactive bladder: alternative treatment approaches].
    Der Urologe. Ausg. A, 2011, Volume: 50, Issue:7

    Topics: Administration, Intravesical; Botulinum Toxins, Type A; Cholinergic Antagonists; Complementary Thera

2011
[Capsaicin and lidocaine usage in functional disorders of urinary bladder].
    Folia medica Cracoviensia, 2011, Volume: 51, Issue:1-4

    Topics: Botulinum Toxins; Calcium Channels; Capsaicin; Cholinergic Antagonists; Drug Therapy, Combination; H

2011
Anticholinergic drugs versus other medications for overactive bladder syndrome in adults.
    The Cochrane database of systematic reviews, 2007, Jul-18, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adult; Antidepressive Agents; Cholinergic Antagonists; Dopamine Uptake

2007
Anticholinergic drugs versus other medications for overactive bladder syndrome in adults.
    The Cochrane database of systematic reviews, 2007, Oct-17, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adult; Antidepressive Agents; Cholinergic Antagonists; Dopamine Uptake

2007

Trials

2 trials available for lidocaine and Bladder, Overactive

ArticleYear
Oral phenazopyridine vs intravesical lidocaine for bladder onabotulinumtoxinA analgesia: a randomized controlled trial.
    American journal of obstetrics and gynecology, 2022, Volume: 227, Issue:2

    Topics: Adult; Analgesia; Botulinum Toxins, Type A; Female; Humans; Lidocaine; Pain; Phenazopyridine; Treatm

2022
Safety and tolerability of sedation-free flexible cystoscopy for intradetrusor botulinum toxin-A injection.
    The Journal of urology, 2007, Volume: 177, Issue:3

    Topics: Administration, Intravesical; Anesthetics, Local; Botulinum Toxins, Type A; Cystoscopy; Female; Huma

2007

Other Studies

8 other studies available for lidocaine and Bladder, Overactive

ArticleYear
Open Label, Pilot Evaluation of the Safety and Efficacy of Intravesical Sustained Release System of Lidocaine and Oxybutynin (TRG-100) for Patients With Interstitial Cystitis/Bladder Pain Syndrome, Overactive Bladder and Patients With Retained Ureteral St
    Urology, 2023, Volume: 178

    Topics: Administration, Intravesical; Cystitis, Interstitial; Delayed-Action Preparations; Humans; Lidocaine

2023
Effects of 1% Lidocaine Instillation on Overactive Bladder Induced by Bladder Outlet Obstruction in Rats.
    Urology journal, 2020, 05-16, Volume: 17, Issue:3

    Topics: Administration, Intravesical; Anesthetics, Local; Animals; Disease Models, Animal; Female; Lidocaine

2020
[Guidelines for practical usage of botulinum toxin type A (BoNTA) for refractory idiopathic overactive bladder management].
    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie, 2013, Volume: 23, Issue:17

    Topics: Administration, Intravesical; Anesthetics, Local; Antibiotic Prophylaxis; Anticoagulants; Botulinum

2013
Efficacy of peripheral lidocaine application (neural therapy) in the treatment of neurogenic detrusor overactivity in multiple sclerosis patients.
    Neurourology and urodynamics, 2017, Volume: 36, Issue:7

    Topics: Adult; Anesthetics, Local; Female; Humans; Injections, Epidural; Injections, Intradermal; Lidocaine;

2017
Epidural steroid injections in the management of a patient with spinal stenosis and urinary urgency.
    Nature clinical practice. Urology, 2009, Volume: 6, Issue:2

    Topics: Aged; Disease Management; Female; Humans; Injections, Epidural; Lidocaine; Lumbar Vertebrae; Spinal

2009
Electromotive drug-administration: a pilot study for minimal-invasive treatment of therapy-resistant idiopathic detrusor overactivity.
    Neurourology and urodynamics, 2009, Volume: 28, Issue:3

    Topics: Aged; Anesthetics, Local; Anti-Inflammatory Agents; Cholinergic Antagonists; Deamino Arginine Vasopr

2009
Urodynamic effects of the bladder C-fiber afferent activity modulation in chronic model of overactive bladder in rats.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2009, Volume: 60, Issue:4

    Topics: Administration, Intravesical; Afferent Pathways; Anesthetics, Local; Animals; Capsaicin; Cystitis; D

2009
Time-dependent changes in bladder function and plantar sensitivity in a rat model of fibromyalgia syndrome induced by hydrochloric acid injection into the gluteus.
    BJU international, 2012, Volume: 109, Issue:2

    Topics: Anesthetics, Local; Animals; Case-Control Studies; Chronic Pain; Disease Models, Animal; Female; Fib

2012