lidocaine has been researched along with Benign Neoplasms in 66 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Research on the safety and efficacy of continuous lidocaine infusions (CLIs) for the treatment of pain in the pediatric setting is limited." | 9.22 | Continuous Lidocaine Infusions to Manage Opioid-Refractory Pain in a Series of Cancer Patients in a Pediatric Hospital. ( Beckman, EJ; DeMonbrun, A; Gibbons, K; Hakel, S; Keefer, P; Liu, M; Niedner, M; Saul, D; Stewart, M; Wagner, D, 2016) |
| "This study was designed to evaluate the role of epidural methadone-lidocaine in cancer pain combined or not to epidural dexamethasone." | 9.17 | Epidural methadone results in dose-dependent analgesia in cancer pain, further enhanced by epidural dexamethasone. ( Lauretti, GR; Mattos, AL; Rizzo, CC; Rodrigues, SW, 2013) |
| "This retrospective review assesses the safety and efficacy of subcutaneous lidocaine infusions for complex cancer pain, in a specialist palliative care unit." | 8.02 | Subcutaneous Lidocaine Infusion for Complex Cancer Pain: A Retrospective Review. ( Al Ruheili, J; Barham, D; Clark, H; Ferguson, L, 2021) |
| "Four patients experiencing cancer pain with nociceptive and neuropathic components were treated with a continuous intrathecal administration of a mixture of ketamine (10 mg)-morphine (1-20 mg)-clonidine (30 micrograms)-lidocaine (20 mg) in 12 mL of normal saline, injected daily with an infusor (Baxter) pump." | 7.69 | [Cancer pain: beneficial effect of ketamine addition to spinal administration of morphine-clonidine-lidocaine mixture]. ( Lemos, D; Muller, A, 1996) |
| "Opioid-refractory pain is distressing because it is notoriously difficult to treat." | 6.74 | A phase II pilot study to evaluate use of intravenous lidocaine for opioid-refractory pain in cancer patients. ( Haji, AG; Jain, D; Palat, G; Rajagopal, MR; Sharma, S; Singh, C, 2009) |
| "In 10 cancer patients with cutaneous allodynia, intravenous lidocaine (5 mg/kg body weight) or 0." | 6.66 | Trial of intravenous lidocaine on painful neuropathy in cancer patients. ( Banning, AM; Ellemann, K; Geertsen, P; Jensen, TS; Sjögren, P; Smith, T, 1989) |
| "Cough is one of the most common symptoms prompting patients to be seen by health care providers in the United States." | 6.49 | Nebulized lidocaine in the treatment of intractable cough. ( Jurdi, A; Truesdale, K, 2013) |
| "5 mg/kg lignocaine over 15 min, starting approximately 15 min before the surgical incision and fentanyl 0." | 5.69 | A comparison of two techniques of postoperative analgesia: lignocaine-fentanyl intravenous infusion and ropivacaine-fentanyl epidural infusion in patients undergoing cytoreductive cancer surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC)- ( Bharati, SJ; Bhatnagar, S; Deo, S; Garg, R; Gupta, N; Kumar, V; Mahendru, K; Mishra, S; Ray, M, 2023) |
| "Lidocaine cream, cryotherapy and cutaneous stimulation therapy all reduced cancer patients' pain levels during insertion of an implanted central venous access chemoport needle." | 5.51 | Comparing the effectiveness of three pain relief methods for inserting a needle into the implanted venous access chemoport: A randomized controlled trial. ( Kim, GS; Shin, J; Sim, H, 2022) |
| "Research on the safety and efficacy of continuous lidocaine infusions (CLIs) for the treatment of pain in the pediatric setting is limited." | 5.22 | Continuous Lidocaine Infusions to Manage Opioid-Refractory Pain in a Series of Cancer Patients in a Pediatric Hospital. ( Beckman, EJ; DeMonbrun, A; Gibbons, K; Hakel, S; Keefer, P; Liu, M; Niedner, M; Saul, D; Stewart, M; Wagner, D, 2016) |
| "This study was designed to evaluate the role of epidural methadone-lidocaine in cancer pain combined or not to epidural dexamethasone." | 5.17 | Epidural methadone results in dose-dependent analgesia in cancer pain, further enhanced by epidural dexamethasone. ( Lauretti, GR; Mattos, AL; Rizzo, CC; Rodrigues, SW, 2013) |
| " In patients with neuropathic pain, topical forms of both capsaicin and lidocaine have been shown to be useful in the treatment of postherpetic neuralgia and diabetic peripheral neuropathic pain." | 4.89 | Topical therapies in the management of chronic pain. ( Galluzzi, KE; Stanos, SP, 2013) |
| " Lidocaine patches reduce neuropathic pain in postherpetic neuralgia, but their benefits for cancer-related neuropathic pain remain unclear." | 4.31 | Lidocaine transdermal patches reduced pain intensity in neuropathic cancer patients already receiving opioid treatment. ( Chen, YY; Chiu, GL; Huang, YT; Lai, WS; Lin, PC; Liu, IT; Su, PF; Tsai, JH, 2023) |
| "This retrospective review assesses the safety and efficacy of subcutaneous lidocaine infusions for complex cancer pain, in a specialist palliative care unit." | 4.02 | Subcutaneous Lidocaine Infusion for Complex Cancer Pain: A Retrospective Review. ( Al Ruheili, J; Barham, D; Clark, H; Ferguson, L, 2021) |
| " Lidocaine formulations significantly reduced the paw edema on day 6 after Walker 256 cells inoculation." | 3.96 | Effects of 2-Hydroxypropil-Β-Cyclodextrin-Lidocaine on Tumor Growth and Inflammatory Response. ( Abdalla, HB; Burga-Sánchez, J; da Costa, JP; de Freitas Domingues, JS; Ferreira, LEN; Groppo, FC; Volpato, MC, 2020) |
| "Four patients experiencing cancer pain with nociceptive and neuropathic components were treated with a continuous intrathecal administration of a mixture of ketamine (10 mg)-morphine (1-20 mg)-clonidine (30 micrograms)-lidocaine (20 mg) in 12 mL of normal saline, injected daily with an infusor (Baxter) pump." | 3.69 | [Cancer pain: beneficial effect of ketamine addition to spinal administration of morphine-clonidine-lidocaine mixture]. ( Lemos, D; Muller, A, 1996) |
| "Pain was assessed subjectively using the numeric rating scale (NRS) and objectively using a Galvanic Skin Response (GSR) tester." | 2.87 | [The Effect of Pain Relieving Intervention During Infiltration among Gamma Knife Surgery Patients for Stereotactic Frame Fixation]. ( Jang, YJ; Kim, HO, 2018) |
| "Opioid-refractory pain is distressing because it is notoriously difficult to treat." | 2.74 | A phase II pilot study to evaluate use of intravenous lidocaine for opioid-refractory pain in cancer patients. ( Haji, AG; Jain, D; Palat, G; Rajagopal, MR; Sharma, S; Singh, C, 2009) |
| "Twenty-eight cancer patients with postsurgical incisional pain were randomly assigned to receive either lidocaine patches followed by placebo patches or the reverse." | 2.74 | Use of a lidocaine patch in the management of postsurgical neuropathic pain in patients with cancer: a phase III double-blind crossover study (N01CB). ( Bearden Iii, JD; Cheville, AL; Christensen, BJ; Jillella, AP; Liu, H; Loprinzi, CL; Marchello, BT; Northfelt, DW; Schaefer, PL; Sloan, JA; Wong, GY, 2009) |
| "Procedure-related pain is a significant problem for many children receiving cytotoxic chemotherapy." | 2.67 | Trial of a topically administered local anesthetic (EMLA cream) for pain relief during central venous port accesses in children with cancer. ( Arnold, M; Betcher, DL; Dose, AM; Goh, TS; Loprinzi, CL; MacKellar, DJ; Miser, AW; Niedringhaus, RD; O'Fallon, JR; Simmons, P, 1994) |
| "In 10 cancer patients with cutaneous allodynia, intravenous lidocaine (5 mg/kg body weight) or 0." | 2.66 | Trial of intravenous lidocaine on painful neuropathy in cancer patients. ( Banning, AM; Ellemann, K; Geertsen, P; Jensen, TS; Sjögren, P; Smith, T, 1989) |
| "Multiple causes of neuropathic pain have been described and its incidence is likely to increase owing to the ageing global population, increased incidence of diabetes mellitus and improved survival from cancer after chemotherapy." | 2.55 | Neuropathic pain. ( Attal, N; Baron, R; Bennett, DL; Bouhassira, D; Colloca, L; Dickenson, AH; Dworkin, RH; Eccleston, C; Finnerup, NB; Freeman, R; Kalso, E; Ludman, T; Raja, SN; Truini, A; Yarnitsky, D, 2017) |
| "Cough is one of the most common symptoms prompting patients to be seen by health care providers in the United States." | 2.49 | Nebulized lidocaine in the treatment of intractable cough. ( Jurdi, A; Truesdale, K, 2013) |
| "The growth of human cancer cell lines, including HeLa cells, are suppressed by lidocaine treatment." | 1.72 | Local anesthetic lidocaine-inducible gene, growth differentiation factor-15 suppresses the growth of cancer cell lines. ( Haraguchi-Suzuki, K; Kawabata-Iwakawa, R; Saito, S; Suto, T; Suzuki, T; Takazawa, T, 2022) |
| " Utilizing a 90-day BUD, lidocaine can be packaged separately from other magic mouthwash ingredients in individual dosage units and applied to the oral cavity using the swish-and-spit method." | 1.46 | Beyond-use dating of lidocaine alone and in two "magic mouthwash" preparations. ( Brown, SD; Huffman, J; Kirk, LM; Lewis, PO; Luu, Y; Ogle, A, 2017) |
| "Lidocaine was subjectively deemed effective in 10/22 episodes (45%)." | 1.46 | Subcutaneous Lidocaine Infusion for Pain in Patients with Cancer. ( Fullerton, S; Herschtal, A; Seah, DSE; Thakerar, A; Tran, H, 2017) |
| "Lidocaine infusion is a useful option to consider when other pain treatments have not been successful." | 1.42 | Intravenous lidocaine for cancer pain without electrocardiographic monitoring: a retrospective review. ( Hawley, P; Peixoto, RD, 2015) |
| "The University of Washington Neuropathic Pain Scale was used to grade the neuropathic pain before and after use of the interventional gel." | 1.38 | Topical amitriptyline, ketamine, and lidocaine in neuropathic pain caused by radiation skin reaction: a pilot study. ( Gerbis, B; Gillis, D; Holwerda, E; Uzaraga, I; Wai, E, 2012) |
| "Ischiogluteal bursitis is an easily diagnosed condition that can be effectively treated with local injection of corticosteroids." | 1.29 | Ischiogluteal bursitis in cancer patients: an infrequently recognized cause of pain. ( Baethge, BA; Mills, GM, 1993) |
| "Three patients with terminal malignancy reporting ineffective analgesia using systemic and subsequently spinal opiates were treated with subcutaneous infusion of 10% lidocaine hydrochloride." | 1.28 | Subcutaneous lidocaine for treatment of neuropathic cancer pain. ( Brose, WG; Cousins, MJ, 1991) |
| "Patients with cancer had increased serum concentrations of the acute-phase protein alpha 1-acid glycoprotein (AAG) and lowered serum concentration of albumin." | 1.26 | Altered plasma drug binding in cancer: role of alpha 1-acid glycoprotein and albumin. ( Jackson, PR; Tucker, GT; Woods, HF, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (18.18) | 18.7374 |
| 1990's | 13 (19.70) | 18.2507 |
| 2000's | 7 (10.61) | 29.6817 |
| 2010's | 22 (33.33) | 24.3611 |
| 2020's | 12 (18.18) | 2.80 |
| Authors | Studies |
|---|---|
| How, SW | 1 |
| Cheng, AL | 1 |
| Haraguchi-Suzuki, K | 1 |
| Kawabata-Iwakawa, R | 1 |
| Suzuki, T | 1 |
| Suto, T | 1 |
| Takazawa, T | 1 |
| Saito, S | 1 |
| Chandra, S | 1 |
| Pryambodho, P | 1 |
| Omega, A | 1 |
| Tsai, JH | 1 |
| Liu, IT | 1 |
| Su, PF | 1 |
| Huang, YT | 1 |
| Chiu, GL | 1 |
| Chen, YY | 1 |
| Lai, WS | 1 |
| Lin, PC | 1 |
| Lee, J | 1 |
| Currow, D | 1 |
| Lovell, M | 1 |
| Phillips, JL | 1 |
| McLachlan, A | 1 |
| Ritchie, M | 1 |
| Brown, L | 1 |
| Fazekas, B | 1 |
| Aggarwal, R | 1 |
| Seah, D | 1 |
| Sheehan, C | 1 |
| Chye, R | 1 |
| Noble, B | 1 |
| McCaffrey, N | 1 |
| Aggarwal, G | 1 |
| George, R | 1 |
| Kow, M | 1 |
| Ayoub, C | 1 |
| Linton, A | 1 |
| Sanderson, C | 1 |
| Mittal, D | 1 |
| Rao, A | 1 |
| Prael, G | 1 |
| Urban, K | 1 |
| Vandersman, P | 1 |
| Agar, M | 1 |
| Mahendru, K | 1 |
| Garg, R | 1 |
| Bharati, SJ | 1 |
| Kumar, V | 1 |
| Gupta, N | 1 |
| Mishra, S | 1 |
| Bhatnagar, S | 1 |
| Ray, M | 1 |
| Deo, S | 1 |
| van Haren, F | 1 |
| van den Heuvel, S | 1 |
| Radema, S | 1 |
| van Erp, N | 1 |
| van den Bersselaar, L | 1 |
| Vissers, K | 1 |
| Steegers, M | 1 |
| Ferreira, LEN | 1 |
| Abdalla, HB | 1 |
| da Costa, JP | 1 |
| de Freitas Domingues, JS | 1 |
| Burga-Sánchez, J | 1 |
| Groppo, FC | 1 |
| Volpato, MC | 1 |
| Chong, PH | 1 |
| Yeo, ZZ | 1 |
| Dubowitz, J | 1 |
| Toner, A | 1 |
| Riedel, B | 1 |
| Corcoran, T | 1 |
| Shin, J | 1 |
| Kim, GS | 1 |
| Sim, H | 1 |
| Ferguson, L | 1 |
| Al Ruheili, J | 1 |
| Clark, H | 1 |
| Barham, D | 1 |
| Anghelescu, DL | 1 |
| Morgan, KJ | 1 |
| Frett, MJ | 1 |
| Wu, D | 1 |
| Li, Y | 1 |
| Han, Y | 1 |
| Hall, EA | 1 |
| Kirk, LM | 1 |
| Brown, SD | 1 |
| Luu, Y | 1 |
| Ogle, A | 1 |
| Huffman, J | 1 |
| Lewis, PO | 1 |
| Cata, JP | 1 |
| Ramirez, MF | 1 |
| Velasquez, JF | 1 |
| Di, AI | 1 |
| Popat, KU | 1 |
| Gottumukkala, V | 1 |
| Black, DM | 1 |
| Lewis, VO | 1 |
| Vauthey, JN | 1 |
| Jang, YJ | 1 |
| Kim, HO | 1 |
| Lynch, C | 1 |
| Abyar, F | 1 |
| Tabrizi, L | 3 |
| Huang, R | 1 |
| Jiang, L | 1 |
| Cao, Y | 1 |
| Liu, H | 2 |
| Ping, M | 1 |
| Li, W | 1 |
| Xu, Y | 1 |
| Ning, J | 1 |
| Chen, Y | 1 |
| Wang, X | 1 |
| Kaneishi, K | 1 |
| Stanos, SP | 1 |
| Galluzzi, KE | 1 |
| Salas, S | 1 |
| Auquier, P | 1 |
| Duffaud, F | 1 |
| Garnier, SR | 1 |
| Deschamps, M | 1 |
| Honoré, S | 1 |
| Sudour, P | 1 |
| Baumstarck, K | 1 |
| Peixoto, RD | 1 |
| Hawley, P | 1 |
| Gibbons, K | 1 |
| DeMonbrun, A | 1 |
| Beckman, EJ | 1 |
| Keefer, P | 1 |
| Wagner, D | 1 |
| Stewart, M | 1 |
| Saul, D | 1 |
| Hakel, S | 1 |
| Liu, M | 1 |
| Niedner, M | 1 |
| Berde, C | 1 |
| Koka, A | 1 |
| Donado-Rincon, C | 1 |
| Chiniforoshan, H | 2 |
| Seah, DSE | 1 |
| Herschtal, A | 1 |
| Tran, H | 1 |
| Thakerar, A | 1 |
| Fullerton, S | 1 |
| Colloca, L | 1 |
| Ludman, T | 1 |
| Bouhassira, D | 1 |
| Baron, R | 1 |
| Dickenson, AH | 1 |
| Yarnitsky, D | 1 |
| Freeman, R | 1 |
| Truini, A | 1 |
| Attal, N | 1 |
| Finnerup, NB | 1 |
| Eccleston, C | 1 |
| Kalso, E | 1 |
| Bennett, DL | 1 |
| Dworkin, RH | 1 |
| Raja, SN | 1 |
| Sharma, S | 1 |
| Rajagopal, MR | 1 |
| Palat, G | 1 |
| Singh, C | 1 |
| Haji, AG | 1 |
| Jain, D | 1 |
| Cheville, AL | 1 |
| Sloan, JA | 1 |
| Northfelt, DW | 1 |
| Jillella, AP | 1 |
| Wong, GY | 1 |
| Bearden Iii, JD | 1 |
| Schaefer, PL | 1 |
| Marchello, BT | 1 |
| Christensen, BJ | 1 |
| Loprinzi, CL | 2 |
| Fujii, T | 1 |
| Nagaro, T | 1 |
| Tsubota, S | 1 |
| Takechi, K | 1 |
| Higaki, N | 1 |
| Yorozuya, T | 1 |
| Uzaraga, I | 1 |
| Gerbis, B | 1 |
| Holwerda, E | 1 |
| Gillis, D | 1 |
| Wai, E | 1 |
| Kintzel, PE | 1 |
| Mulder, JA | 1 |
| Truesdale, K | 1 |
| Jurdi, A | 1 |
| López Ramírez, E | 1 |
| Lauretti, GR | 1 |
| Rizzo, CC | 1 |
| Mattos, AL | 1 |
| Rodrigues, SW | 1 |
| Mercadante, S | 2 |
| Villari, P | 2 |
| Ferrera, P | 2 |
| Arcuri, E | 2 |
| RIDING, JE | 1 |
| LEAHEY, EB | 1 |
| BUSCICCHI, EJ | 1 |
| NOTO, A | 1 |
| ROONEY, JJ | 1 |
| Tei, Y | 1 |
| Morita, T | 1 |
| Shishido, H | 1 |
| Inoue, S | 1 |
| Bruera, E | 1 |
| Ripamonti, C | 1 |
| Brenneis, C | 1 |
| Macmillan, K | 1 |
| Hanson, J | 1 |
| Thomson, DM | 1 |
| Phelan, K | 1 |
| Scanzano, R | 1 |
| Fink, A | 1 |
| Jackson, PR | 1 |
| Tucker, GT | 1 |
| Woods, HF | 1 |
| Joshi, JH | 1 |
| Wang, KP | 1 |
| de Jongh, CA | 1 |
| Newman, KA | 1 |
| Wiernik, PH | 1 |
| Schimpff, SC | 1 |
| Gestin, Y | 1 |
| Marty-Ane, I | 1 |
| Brulé-Fermand, S | 1 |
| Wilcock, A | 1 |
| Corcoran, R | 1 |
| Tattersfield, AE | 1 |
| Miser, AW | 1 |
| Goh, TS | 1 |
| Dose, AM | 1 |
| O'Fallon, JR | 1 |
| Niedringhaus, RD | 1 |
| Betcher, DL | 2 |
| Simmons, P | 1 |
| MacKellar, DJ | 1 |
| Arnold, M | 1 |
| Goede, IA | 1 |
| Mills, GM | 1 |
| Baethge, BA | 1 |
| Cannizzaro, R | 1 |
| Robieux, I | 1 |
| Valentini, M | 1 |
| Sorio, R | 1 |
| Amoroso, B | 1 |
| Tumolo, S | 1 |
| Campagnutta, E | 1 |
| Muller, A | 1 |
| Lemos, D | 1 |
| Bogár, L | 1 |
| Horváth, JA | 1 |
| Tekeres, M | 1 |
| Dionne, R | 1 |
| Turhal, NS | 1 |
| Erdal, S | 1 |
| Karacay, S | 1 |
| D'Olimpio, J | 1 |
| Le Pivert, P | 1 |
| Binder, P | 1 |
| Barnett, TA | 1 |
| Kapp, DS | 1 |
| Brose, WG | 1 |
| Cousins, MJ | 1 |
| Ellemann, K | 1 |
| Sjögren, P | 1 |
| Banning, AM | 1 |
| Jensen, TS | 1 |
| Smith, T | 1 |
| Geertsen, P | 1 |
| Vigué, B | 1 |
| Kuhlman, G | 1 |
| Fetcher, F | 1 |
| Mazoit, JX | 1 |
| Cameron, DJ | 1 |
| Caminiti, G | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Continous Intravenous Lidocaine Infusion Intraoperative for Craniotomy Tumor Removal Surgery: Effect to Brain Relaxation, Opioid Consumption and Postoperative Cognitive Status[NCT04773093] | Phase 1/Phase 2 | 50 participants (Anticipated) | Interventional | 2021-01-01 | Recruiting | ||
| Intravenous Lidocaine Infusion Versus Oral Duloxetine For The Prevention And Treatment Of Chemotherapy Induced Peripheral Neuropathy Among Breast Cancer Patients[NCT04732455] | 60 participants (Actual) | Interventional | 2021-01-15 | Completed | |||
| Comparison of The Effects Of General Anesthesia and PECS Block Methods on Blood Leukocyte, Neutrophil, Lymphocyte, and Platelet Counts in Patients With Breast Cancer[NCT06151639] | 26 participants (Actual) | Observational | 2022-08-01 | Completed | |||
| Effect of Buffered Lidocaine With Epinephrine in Local Anesthesia During Subcutaneous Implantable Venous Access Devices Insertion: Double Blind Randomized Study.[NCT03628430] | 120 participants (Actual) | Interventional | 2017-01-01 | Completed | |||
| Trial Evaluating multimOdal toPical Cream In CompArison to pLacebo (TOPICAL)[NCT03199417] | Phase 2/Phase 3 | 50 participants (Actual) | Interventional | 2017-05-01 | Terminated (stopped due to Terminated prematurely due to feasibility issues with rate of recruitment) | ||
| Efficacy of Lidocaine Versus Placebo in Palliative Care Patients With Opioid-refractory Cancer Pain With Neuropathic Component: a Multicenter, Prospective, Double-blind Randomized Placebo-controlled Study.[NCT02137954] | Phase 3 | 200 participants (Anticipated) | Interventional | 2014-05-31 | Recruiting | ||
| BotulInum Toxin Type A for Peripheral Neuropathic Pain in subjEcts With Carpal Tunnel Syndrome: a Multicenter, Randomized, Doubleblind, Placebo-controlled Study[NCT05411900] | Phase 2 | 164 participants (Anticipated) | Interventional | 2022-05-25 | Recruiting | ||
| Hypogastric Plexus Block and Ganglion Impar Block for Cervical and Endometrial Cancer Pain Management: A Randomized Controlled Trial of Efficacy and Safety[NCT05427058] | 36 participants (Anticipated) | Interventional | 2022-08-01 | Not yet recruiting | |||
| Neuropathic Foot and Ankle in Rheumatoid Arthritis : Ultrasound and Nerve Conduction Study[NCT04550884] | 80 participants (Anticipated) | Observational | 2020-10-31 | Not yet recruiting | |||
| NanaBis™ an Oro-buccal Administered Equimolar d9-THC & CBD Formulation as Monotherapy for Management of Opioid Requiring Bone Pain Due to Metastatic Cancer: Phase 3 Multi Centre Blinded Randomized Withdrawal Active & Placebo Controlled Trial[NCT04808531] | Phase 3 | 360 participants (Anticipated) | Interventional | 2023-11-30 | Not yet recruiting | ||
| Diode Laser as a Biomarker for Neuropathic Pain of Peripheral Origin.[NCT06030297] | 301 participants (Anticipated) | Interventional | 2022-11-01 | Recruiting | |||
| The Study of Perioperative Intravenous Infusion of Lidocaine on Postoperative Analgesia in Patients Undergoing Single-port Thoracoscopic[NCT04043624] | Phase 4 | 80 participants (Anticipated) | Interventional | 2019-08-01 | Recruiting | ||
| The Efficacy Of Lidocaine Patch In The Management Of Postsurgical Neuropathic Pain In Patients With Cancer: A Phase III Double-Blind, Crossover Study[NCT00058357] | Phase 3 | 30 participants (Actual) | Interventional | 2004-05-31 | Completed | ||
| The PATCH Trial: Effectiveness and Safety of 5% Lidocaine-medicated Plaster for the Treatment of Trigeminal Neuralgia[NCT04570293] | Phase 4 | 226 participants (Actual) | Interventional | 2021-05-01 | Completed | ||
| Antipruritic Effect of Topical Ketamine, Amitriptyline, and Lidocaine[NCT03096444] | Phase 2 | 13 participants (Actual) | Interventional | 2017-05-23 | Terminated (stopped due to Efficacy was not seen after interim analysis) | ||
| Study of the Efficiency of the Ketamine With Low Analgesic Doses, in Association With High Opioids, in the Treatment of the Rebels Pains, in Palliative Phase of the Cancerous Disease[NCT01326325] | Phase 3 | 24 participants (Actual) | Interventional | 2011-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Peak itch intensity between the vehicle and 4 other active treatments (individual ketamine, amitriptyline, or lidocaine, and KeAmLi-combo). Itch intensity was measured on a 100mm scale visual analog scale for 10 minutes. 0 was weighted with no itch and 100 was weighted with most itch imaginable." (NCT03096444)
Timeframe: 10 minutes
| Intervention | Intensity score (Mean) |
|---|---|
| Topical KeAmLi Combo | 62.7 |
| Topical Ketamine | 63.1 |
| Topical Amitriptyline | 69.2 |
| Topical Lidocaine | 65.8 |
| Topical Vehicle | 61.9 |
Assess mechanical detection and pain thresholds using von Frey filaments stimulators (measured in force mN) to calculate the final threshold as the geometric mean of five series of ascending and descending stimuli. (NCT03096444)
Timeframe: 5 minutes
| Intervention | mN (Mean) | |
|---|---|---|
| Mechanical Detection Threshold | Mechanical Pain Threshold | |
| Topical Amitriptyline | 3.573423965 | 152.4768146 |
| Topical KeAmLi Combo | 3.519376956 | 152.3293608 |
| Topical Ketamine | 3.464204768 | 135.9 |
| Topical Lidocaine | 3.546037659 | 126.9 |
| Topical Vehicle | 3.525692637 | 148.7138273 |
Two standardized quantitative sensory tests are performed to measure warmth detection threshold (assesses the threshold of which warmth sensation is first detected) and heat pain threshold (assesses the threshold at which heat pain sensation is first detected). Measured in change in celsius. (NCT03096444)
Timeframe: 3 minutes
| Intervention | Degrees celsius (Mean) | |
|---|---|---|
| Warm Detection Threshold | Heat Pain Threshold | |
| Topical Amitriptyline | 33.9 | 40.0 |
| Topical KeAmLi Combo | 33.6 | 39.8 |
| Topical Ketamine | 34.0 | 40.0 |
| Topical Lidocaine | 33.7 | 39.4 |
| Topical Vehicle | 33.8 | 39.7 |
9 reviews available for lidocaine and Benign Neoplasms
| Article | Year |
|---|---|
Parenteral Lidocaine for Complex Cancer Pain in the Home or Inpatient Hospice Setting: A Review and Synthesis of the Evidence.
Topics: Anesthetics, Local; Cancer Pain; Hospices; Humans; Inpatients; Lidocaine; Neoplasms; Retrospective S | 2021 |
Lidocaine Stimulates the Function of Natural Killer Cells in Different Experimental Settings.
Topics: Biomarkers; Cell Differentiation; Cell Line, Tumor; Humans; Killer Cells, Natural; Lidocaine; Lympho | 2017 |
Comparative Efficacy of Therapeutics for Chronic Cancer Pain: A Bayesian Network Meta-Analysis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bayes Theorem; Bridged Bicyclo Compou | 2019 |
Topical therapies in the management of chronic pain.
Topics: Administration, Cutaneous; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; C | 2013 |
Lidocaine Infusions and Other Options for Opioid-Resistant Pain Due to Pediatric Advanced Cancer.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Resistance; Female; Humans; Infant; Li | 2016 |
Neuropathic pain.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminob | 2017 |
Neuropathic pain.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminob | 2017 |
Neuropathic pain.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminob | 2017 |
Neuropathic pain.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminob | 2017 |
Neuropathic pain.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminob | 2017 |
Neuropathic pain.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminob | 2017 |
Neuropathic pain.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminob | 2017 |
Neuropathic pain.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminob | 2017 |
Neuropathic pain.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminob | 2017 |
Neuropathic pain.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminob | 2017 |
Neuropathic pain.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminob | 2017 |
Neuropathic pain.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminob | 2017 |
Neuropathic pain.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminob | 2017 |
Neuropathic pain.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminob | 2017 |
Neuropathic pain.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminob | 2017 |
Neuropathic pain.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminob | 2017 |
Neuropathic pain.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminob | 2017 |
Neuropathic pain.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminob | 2017 |
Neuropathic pain.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminob | 2017 |
Neuropathic pain.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminob | 2017 |
Neuropathic pain.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminob | 2017 |
Neuropathic pain.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminob | 2017 |
Neuropathic pain.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminob | 2017 |
Neuropathic pain.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminob | 2017 |
Neuropathic pain.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminob | 2017 |
Nebulized lidocaine in the treatment of intractable cough.
Topics: Administration, Inhalation; Anesthetics, Local; Cough; Humans; Lidocaine; Lung Neoplasms; Nebulizers | 2013 |
EMLA.
Topics: Anesthetics, Local; Child; Drug Combinations; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combinat | 1994 |
Contemporary drug therapy in palliative care: new directions.
Topics: Adrenal Cortex Hormones; Analgesics; Anorexia; Antiemetics; Antitussive Agents; Cachexia; Cough; Dru | 2001 |
17 trials available for lidocaine and Benign Neoplasms
| Article | Year |
|---|---|
Evaluation of continuous intravenous lidocaine on brain relaxation, intraoperative opioid consumption, and surgeon's satisfaction in adult patients undergoing craniotomy tumor surgery: A randomized controlled trial.
Topics: Adult; Analgesics, Opioid; Anesthetics, Local; Brain; Craniotomy; Humans; Lidocaine; Neoplasms; Pain | 2022 |
Lidocaine for Neuropathic Cancer Pain (LiCPain): study protocol for a mixed-methods pilot study.
Topics: Cancer Pain; Clinical Trials, Phase II as Topic; Humans; Lidocaine; Neoplasms; Neuralgia; Pilot Proj | 2023 |
A comparison of two techniques of postoperative analgesia: lignocaine-fentanyl intravenous infusion and ropivacaine-fentanyl epidural infusion in patients undergoing cytoreductive cancer surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC)-
Topics: Analgesia, Epidural; Cytoreduction Surgical Procedures; Fentanyl; Humans; Hyperthermic Intraperitone | 2023 |
Comparing the effectiveness of three pain relief methods for inserting a needle into the implanted venous access chemoport: A randomized controlled trial.
Topics: Anesthetics, Local; Humans; Lidocaine; Neoplasms; Pain; Pain Measurement | 2022 |
[The Effect of Pain Relieving Intervention During Infiltration among Gamma Knife Surgery Patients for Stereotactic Frame Fixation].
Topics: Aged; Anesthetics, Local; Blood Pressure; Female; Heart Rate; Humans; Hypothermia, Induced; Lidocain | 2018 |
Efficacy of lidocaine in patients receiving palliative care with opioid-refractory cancer pain with a neuropathic component: study protocol for a randomized controlled study.
Topics: Administration, Intravenous; Anesthetics, Local; Clinical Protocols; Double-Blind Method; Drug Resis | 2014 |
Continuous Lidocaine Infusions to Manage Opioid-Refractory Pain in a Series of Cancer Patients in a Pediatric Hospital.
Topics: Adolescent; Analgesics, Opioid; Child; Drug Resistance; Female; Humans; Lidocaine; Male; Neoplasms; | 2016 |
A phase II pilot study to evaluate use of intravenous lidocaine for opioid-refractory pain in cancer patients.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anesthetics, Local; Cross-Over Studies; Double-B | 2009 |
Use of a lidocaine patch in the management of postsurgical neuropathic pain in patients with cancer: a phase III double-blind crossover study (N01CB).
Topics: Administration, Cutaneous; Aged; Anesthetics, Local; Cross-Over Studies; Double-Blind Method; Female | 2009 |
Use of a lidocaine patch in the management of postsurgical neuropathic pain in patients with cancer: a phase III double-blind crossover study (N01CB).
Topics: Administration, Cutaneous; Aged; Anesthetics, Local; Cross-Over Studies; Double-Blind Method; Female | 2009 |
Use of a lidocaine patch in the management of postsurgical neuropathic pain in patients with cancer: a phase III double-blind crossover study (N01CB).
Topics: Administration, Cutaneous; Aged; Anesthetics, Local; Cross-Over Studies; Double-Blind Method; Female | 2009 |
Use of a lidocaine patch in the management of postsurgical neuropathic pain in patients with cancer: a phase III double-blind crossover study (N01CB).
Topics: Administration, Cutaneous; Aged; Anesthetics, Local; Cross-Over Studies; Double-Blind Method; Female | 2009 |
Epidural methadone results in dose-dependent analgesia in cancer pain, further enhanced by epidural dexamethasone.
Topics: Adult; Aged; Analgesia, Epidural; Dexamethasone; Drug Administration Routes; Female; Humans; Lidocai | 2013 |
A randomized double-blind crossover trial of intravenous lidocaine in the treatment of neuropathic cancer pain.
Topics: Anesthetics, Local; Cross-Over Studies; Double-Blind Method; Female; Humans; Injections, Intravenous | 1992 |
Trial of a topically administered local anesthetic (EMLA cream) for pain relief during central venous port accesses in children with cancer.
Topics: Administration, Cutaneous; Adolescent; Adult; Anesthetics, Local; Antineoplastic Agents; Child; Chil | 1994 |
Liver function assessment by MEGX. Application to oncology.
Topics: Adult; Aged; Aged, 80 and over; Evaluation Studies as Topic; Female; Humans; Lidocaine; Liver; Liver | 1996 |
[Leukocyte migration during erythrocyte sedimentation].
Topics: Adult; Aged; Anesthetics, Local; Anti-Inflammatory Agents; Blood Sedimentation; Blood Viscosity; Fem | 1997 |
Efficacy of treatment to relieve mucositis-induced discomfort.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Antineoplastic Agents; Diphenhydrami | 2000 |
Reduction of pain and local complications when buffered lidocaine solution is used as a local anesthetic in conjunction with hyperthermia treatments: results of a randomized trial.
Topics: Buffers; Catheterization; Female; Humans; Hydrogen-Ion Concentration; Hyperthermia, Induced; Lidocai | 1992 |
Trial of intravenous lidocaine on painful neuropathy in cancer patients.
Topics: Adult; Aged; Double-Blind Method; Electrocardiography; Female; Humans; Injections, Intravenous; Lido | 1989 |
40 other studies available for lidocaine and Benign Neoplasms
| Article | Year |
|---|---|
Present status of cancer treatment in Taiwan.
Topics: Hepatitis B; Humans; Neoplasms; Taiwan; Vaccination; Viral Hepatitis Vaccines | 1992 |
Local anesthetic lidocaine-inducible gene, growth differentiation factor-15 suppresses the growth of cancer cell lines.
Topics: Anesthetics, Local; Growth Differentiation Factor 15; Growth Differentiation Factor 9; HeLa Cells; H | 2022 |
Lidocaine transdermal patches reduced pain intensity in neuropathic cancer patients already receiving opioid treatment.
Topics: Analgesics; Analgesics, Opioid; Humans; Lidocaine; Neoplasms; Neuralgia; Pain Measurement; Prospecti | 2023 |
Intravenous lidocaine affects oxaliplatin pharmacokinetics in simultaneous infusion.
Topics: Administration, Intravenous; Antineoplastic Combined Chemotherapy Protocols; Cross-Over Studies; Fem | 2020 |
Effects of 2-Hydroxypropil-Β-Cyclodextrin-Lidocaine on Tumor Growth and Inflammatory Response.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Animals; Cell Line, Tumor; Cell Proliferation; Cell Survival; Che | 2020 |
The use of intravenous lidocaine for postoperative pain and recovery.
Topics: Administration, Intravenous; Anesthetics, Local; Clinical Trials as Topic; Humans; Lidocaine; Neopla | 2021 |
Subcutaneous Lidocaine Infusion for Complex Cancer Pain: A Retrospective Review.
Topics: Analgesics, Opioid; Anesthetics, Local; Cancer Pain; Humans; Infusions, Intravenous; Lidocaine; Neop | 2021 |
Lidocaine infusions and reduced opioid consumption-Retrospective experience in pediatric hematology and oncology patients with refractory pain.
Topics: Analgesics, Opioid; Anesthetics, Local; Child; Hematology; Humans; Infusions, Intravenous; Lidocaine | 2021 |
Beyond-use dating of lidocaine alone and in two "magic mouthwash" preparations.
Topics: Administration, Oral; Aluminum Hydroxide; Analgesics; Antineoplastic Agents; Diphenhydramine; Drug C | 2017 |
Local Anesthetics as…Cancer Therapy?
Topics: Anesthetics; Anesthetics, Local; Humans; Infant, Newborn; Levobupivacaine; Lidocaine; Neoplasms | 2018 |
New multinuclear Scaffold molybdocene-gold lidocaine complex: DNA/HSA binding, molecular docking, cytotoxicity and mechanistic insights.
Topics: Antineoplastic Agents; Binding Sites; Cell Proliferation; DNA; Gold; HEK293 Cells; Humans; Lidocaine | 2019 |
Lidocaine may be effective in alleviating physical symptoms in cancer patients.
Topics: Anesthetics, Local; Humans; Lidocaine; Neoplasms; Pain; Pain Management | 2014 |
Intravenous lidocaine for cancer pain without electrocardiographic monitoring: a retrospective review.
Topics: Cancer Care Facilities; Cardiovascular System; Electrocardiography; Guyana; Humans; Infusions, Intra | 2015 |
New water-soluble palladium(II) complexes of lidocaine and phenylcyanamide derivative ligands: cytotoxicity and cellular response mechanisms.
Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Coordination Complexes; Cyanamide; Humans; Lid | 2016 |
Cytotoxicity and cellular response mechanisms of water-soluble platinum(II) complexes of lidocaine and phenylcyanamide derivatives.
Topics: A549 Cells; Antineoplastic Agents; Apoptosis; Cell Proliferation; Cisplatin; Cyanamide; DNA; Hep G2 | 2017 |
Subcutaneous Lidocaine Infusion for Pain in Patients with Cancer.
Topics: Adult; Aged; Anesthetics, Local; Female; Humans; Infusions, Subcutaneous; Lidocaine; Male; Medical A | 2017 |
Case reports: management of intractable upper extremity pain with continuous subarachnoid block at the low cervical level without impairment of upper extremity function.
Topics: Analgesics, Opioid; Anesthetics, Local; Cervical Vertebrae; Fatal Outcome; Humans; Lidocaine; Male; | 2010 |
Topical amitriptyline, ketamine, and lidocaine in neuropathic pain caused by radiation skin reaction: a pilot study.
Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Amitriptyline; Analgesics; Anesthetics, L | 2012 |
Intravenous lidocaine for management of wound care pain.
Topics: Analgesics, Opioid; Female; Humans; Lidocaine; Male; Neoplasms; Pain; Pain Measurement | 2012 |
Treatment of acute and chronic focal neuropathic pain in cancer patients with lidocaine 5 % patches. A radiation and oncology department experience.
Topics: Acute Pain; Aged; Aged, 80 and over; Anesthetics, Local; Chronic Pain; Female; Humans; Lidocaine; Ma | 2013 |
Local anesthetic switching for intrathecal tachyphylaxis in cancer patients with pain.
Topics: Adult; Anesthetics, Local; Bupivacaine; Carcinoma, Small Cell; Endometrial Neoplasms; Female; Humans | 2003 |
LOCAL ANAESTHETICS FOR CHRONIC PAIN.
Topics: Anesthesia, Local; Anesthetics; Anesthetics, Local; Autonomic Nerve Block; Chronic Pain; Geriatrics; | 1964 |
UPPER-ARM BLOCK ANESTHESIA. A CRITICAL ANALYSIS.
Topics: Adolescent; Anesthesia; Anesthesia, Conduction; Arm; Arm Injuries; Child; Elbow; Forearm Injuries; F | 1964 |
Local anesthetic switching for intrathecal tachyphylaxis in cancer patients with pain.
Topics: Analgesics, Opioid; Anesthetics, Dissociative; Anesthetics, Local; Bupivacaine; Humans; Injections, | 2004 |
Lidocaine intoxication at very small doses in terminally ill cancer patients.
Topics: Aged; Aged, 80 and over; Anesthetics, Local; Disorders of Excessive Somnolence; Dose-Response Relati | 2005 |
The regulation of the human antitumor immune response to organ-specific neoantigens.
Topics: Antigens, Neoplasm; Calcium; Humans; Immunity, Cellular; Ion Channels; Leukocyte Adherence Inhibitio | 1981 |
Altered plasma drug binding in cancer: role of alpha 1-acid glycoprotein and albumin.
Topics: Female; Humans; Lidocaine; Male; Middle Aged; Neoplasms; Orosomucoid; Pharmaceutical Preparations; P | 1982 |
A comparative evaluation of two fiberoptic bronchoscopy catheters: the plugged telescoping catheter versus the single sheathed nonplugged catheter.
Topics: Aerosols; Bronchoscopes; Catheterization; Fiber Optic Technology; Humans; Lidocaine; Neoplasms; Pros | 1982 |
[Splanchnic nerve blocks by alcoholisation in pancreatico-solar hyperalgia of tumoral origin (author's transl)].
Topics: Adult; Aged; Autonomic Nerve Block; Ethanol; Female; Humans; Lidocaine; Male; Middle Aged; Neoplasms | 1981 |
[Treatment of chronic cancer pain. Contribution of acupuncture, auriculotherapy and mesotherapy].
Topics: Acupuncture Therapy; Humans; Lidocaine; Neoplasms; Pain; Pain Management; Palliative Care; Reflexoth | 1993 |
Safety and efficacy of nebulized lignocaine in patients with cancer and breathlessness.
Topics: Administration, Intranasal; Aged; Female; Humans; Lidocaine; Male; Nebulizers and Vaporizers; Neopla | 1994 |
Ischiogluteal bursitis in cancer patients: an infrequently recognized cause of pain.
Topics: Adrenal Cortex Hormones; Adult; Aged; Bursitis; Buttocks; Female; Humans; Injections; Ischium; Lidoc | 1993 |
[Cancer pain: beneficial effect of ketamine addition to spinal administration of morphine-clonidine-lidocaine mixture].
Topics: Aged; Analgesics; Catheters, Indwelling; Clonidine; Drug Combinations; Drug Synergism; Female; Human | 1996 |
Lidocaine and cancer: risk or rumor?
Topics: Anesthetics, Local; Animals; Humans; Lidocaine; Liver; Neoplasms | 1998 |
["In situ" anesthetics and experimental cryotumorectomy].
Topics: Alfaxalone Alfadolone Mixture; Anesthetics; Animals; Cryosurgery; HeLa Cells; Lidocaine; Neoplasms; | 1977 |
Subcutaneous lidocaine for treatment of neuropathic cancer pain.
Topics: Female; Humans; Injections, Subcutaneous; Lidocaine; Male; Middle Aged; Neoplasms; Pain, Intractable | 1991 |
[Pharmacokinetics of lidocaine after intercostal block in cholestatic patients].
Topics: Aged; Cholestasis; Humans; Intercostal Nerves; Lidocaine; Neoplasms; Nerve Block | 1989 |
Lidocaine inhibits macrophage mediated cytotoxicity and enhances neutrophil mediated cytotoxicity.
Topics: Antineoplastic Agents; Cell Line; Cytotoxicity, Immunologic; Humans; Lidocaine; Macrophages; Neoplas | 1986 |
[The treatment of pain in patients with inoperable tumors, using xylocaine and cyclophosphamide of nitrogen mustard].
Topics: Cyclophosphamide; Humans; Lidocaine; Neoplasms; Palliative Care | 1966 |
[Possibilities of antalgic therapy in patients with inoperable tumors].
Topics: Antineoplastic Agents; Dextrans; Humans; Hydrocortisone; Lidocaine; Neoplasms; Palliative Care; Thia | 1966 |