Page last updated: 2024-10-28

lidocaine and Back Ache

lidocaine has been researched along with Back Ache in 120 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Research Excerpts

ExcerptRelevanceReference
"The 5% Lidocaine patch is used for treating chronic neuropathic pain conditions such as chronic back pain (CBP), diabetic neuropathy and complex regional pain syndrome, but is effective in a variable proportion of patients."9.16Lidocaine patch (5%) is no more potent than placebo in treating chronic back pain when tested in a randomised double blind placebo controlled brain imaging study. ( Apkarian, AV; Baliki, MN; Chanda, ML; Hashmi, JA; Huang, L; Parks, EL; Schnitzer, T, 2012)
"Intravenous perioperative lidocaine decreases the incidence and severity of PPSP after breast cancer surgery."9.16Perioperative intravenous lidocaine decreases the incidence of persistent pain after breast surgery. ( Grigoras, A; Lee, P; Sattar, F; Shorten, G, 2012)
"Large doses (> or = 40 ml) of chloroprocaine containing EDTA resulted in a greater incidence of deep burning lumbar back pain."9.07Back pain after epidural anesthesia with chloroprocaine. ( Kao, TC; Stevens, RA; Urmey, WF; Urquhart, BL, 1993)
" Recently, observations have been made that associate the use of hyperbaric lidocaine with bilateral leg pain."7.69Bilateral leg pain following lidocaine spinal anaesthesia. ( Chadwick, HS; Lowmiller, M; Pinczower, GR; Woodland, R, 1995)
"Backache is a common postoperative complaint after lumbar epidural anesthesia."6.69Local supplementation of ketoprofen reduces the incidence of low back pain after lumbar epidural anesthesia. ( Hsieh, JR; Hui, YL; Lau, WM; Ng, YT; Wang, YL; Yu, CC, 1999)
"Addition of dexamethasone to local lidocaine infiltration effectively decreases the incidence and severity of back pain after combined spinal-epidural anesthesia implemented for gynecological surgery."5.20Dexamethasone added to local lidocaine for infiltration along the spinal-epidural needle pathway decreases incidence and severity of backache after gynecological surgery. ( Cui, GX; Gao, W; Ren, Y, 2015)
"The 5% Lidocaine patch is used for treating chronic neuropathic pain conditions such as chronic back pain (CBP), diabetic neuropathy and complex regional pain syndrome, but is effective in a variable proportion of patients."5.16Lidocaine patch (5%) is no more potent than placebo in treating chronic back pain when tested in a randomised double blind placebo controlled brain imaging study. ( Apkarian, AV; Baliki, MN; Chanda, ML; Hashmi, JA; Huang, L; Parks, EL; Schnitzer, T, 2012)
"Intravenous perioperative lidocaine decreases the incidence and severity of PPSP after breast cancer surgery."5.16Perioperative intravenous lidocaine decreases the incidence of persistent pain after breast surgery. ( Grigoras, A; Lee, P; Sattar, F; Shorten, G, 2012)
"Large doses (> or = 40 ml) of chloroprocaine containing EDTA resulted in a greater incidence of deep burning lumbar back pain."5.07Back pain after epidural anesthesia with chloroprocaine. ( Kao, TC; Stevens, RA; Urmey, WF; Urquhart, BL, 1993)
"We conclude that injecting methylprednisolone acetate into the facet joints is of little value in the treatment of patients with chronic low back pain."5.07A controlled trial of corticosteroid injections into facet joints for chronic low back pain. ( Allard, Y; Carette, S; Gagnon, J; Grondin, C; Latulippe, M; Marcoux, S; Truchon, R, 1991)
"Thirty patients with low-back pain of at least one month's duration were included in a double-blind controlled study with third-party administration and treated with either methylprednisolone acetate mixed with lignocaine or isotonic saline, injected at the site of the iliolumbar ligament."5.05Injection of steroids and local anaesthetics as therapy for low-back pain. ( Christensen, K; Hansen, SE; Jensen, EM; Sonne, M, 1985)
"We used mediation analysis methods to examine selected intermediate variables (adverse events and change in leg pain, back pain, disability, depression, and fatigue at 3 wk) as potential mediators of the effect of lumbar epidural injections of corticosteroid plus lidocaine on patient satisfaction with treatment."3.81Short-term improvements in disability mediate patient satisfaction after epidural corticosteroid injections for symptomatic lumbar spinal stenosis. ( Annaswamy, TM; Bauer, Z; Comstock, BA; Friedly, JL; Heagerty, PJ; Jarvik, JG; Nedeljkovic, SS; Pashova, H; Suri, P; Turner, JA; Wasan, AD, 2015)
"The effects of an analgesic treatment (lidocaine patches) on brain activity in chronic low back pain (CBP) and in knee osteoarthritis (OA) were investigated using serial fMRI (contrasting fMRI between before and after two weeks of treatment)."3.74A preliminary fMRI study of analgesic treatment in chronic back pain and knee osteoarthritis. ( Apkarian, AV; Baliki, MN; Geha, PY; Harden, N; Jabakhanji, R; Schnitzer, TJ, 2008)
" Recently, observations have been made that associate the use of hyperbaric lidocaine with bilateral leg pain."3.69Bilateral leg pain following lidocaine spinal anaesthesia. ( Chadwick, HS; Lowmiller, M; Pinczower, GR; Woodland, R, 1995)
"Therapeutic local lidocaine analgesia in the treatment of acute low back pain of functional or degenerative genesis was investigated in 310 patients, with account being taken of additional treatment with NSAIDs."3.68[Therapeutic local anesthesia in acute back pain]. ( Ebeling, L; Ramm, S; Schmitz, H, 1991)
"One hundred patients with posterior compartment lumbar spinal axis pain syndromes and focal tenderness were injected with lidocaine and betamethasone in 194 sites."3.67Computed tomography and fluoroscopy guided anesthesia and steroid injection in facet syndrome. ( Murtagh, FR, 1988)
"Carprofen was administered to Group CG for 70 days, at a dose adjusted to their weight."2.87Evaluation of the effect of mesotherapy in the management of back pain in police working dog. ( Alves, JC; Dos Santos, AM; Fernandes, ÂD, 2018)
"The primary long-term outcome was backache occurring within 3 months of the birth persisting for longer than 6 weeks."2.76Long-term effects of epidural analgesia in labor: a randomized controlled trial comparing high dose with two mobile techniques. ( Lancashire, RJ; MacArthur, C; Moore, PA; Shennan, A; Wilson, MJ, 2011)
"Lidocaine was infiltrated to the skin and the periosteum of the pedicle."2.75Percutaneous vertebroplasty and procedural pain. ( Klazen, CA; Lohle, PN; van Rooij, WJ; Venmans, A, 2010)
"Mepivacaine seems to be a promising alternative to lidocaine for outpatient surgical procedures because of its similar duration of action."2.69Transient neurologic symptoms after spinal anesthesia with mepivacaine and lidocaine. ( Chisholm, MF; Liguori, GA; Zayas, VM, 1998)
"Backache is a common postoperative complaint after lumbar epidural anesthesia."2.69Local supplementation of ketoprofen reduces the incidence of low back pain after lumbar epidural anesthesia. ( Hsieh, JR; Hui, YL; Lau, WM; Ng, YT; Wang, YL; Yu, CC, 1999)
"The incidence of postepidural backache in Group I patients for the 3 days were 22."2.68Epidural dexamethasone reduces the incidence of backache after lumbar epidural anesthesia. ( Chung, HS; Tan, PP; Tsai, SC; Wang, YL; Yang, CH, 1997)
"Thirty-eight injections did not provoke referred pain symptoms and were excluded from further analysis."1.51Induced lumbosacral radicular symptom referral patterns: a descriptive study. ( Furman, MB; Johnson, SC, 2019)
"Axial neck pain is originated from sinuvertebral nerve located in ventral epidural spaces, which has been described to be related to central or paramedian disc herniation."1.43Comparison of Clinical Efficacy Between Interlaminar and Transforaminal Epidural Injection in Patients With Axial Pain due to Cervical Disc Herniation. ( Lee, JH; Lee, SH, 2016)
"A high incidence of backache with radiating pains to the lower extremities, termed transient radicular irritation (TRI), has been reported following the use of 5% hyperbaric lidocaine."1.30Transient radicular irritation (TRI) after spinal anaesthesia in day-care surgery. ( Bach, AB; Corbey, MP, 1998)
"Fentanyl 20 micrograms was added for procedures anticipated to last longer than 45 minutes (but less than 90 min)."1.30Procaine spinal anesthesia: a pilot study of the incidence of transient neurologic symptoms. ( Alexander, GD; Axelrod, EH; Brown, M; Schork, MA, 1998)
"Postoperative backache was experienced by 27 patients."1.30Effect of experience with spinal anaesthesia on the development of post-dural puncture complications. ( Berg, CM; Brekke, S; Flaatten, H; Holmaas, G; Natvik, C; Varughese, K, 1999)
"The occipital pain and headache of cervical arthritis also often respond to injection of 2 to 3 ml of long-acting anesthetic into the greater and lesser occipital nerves at the sites where they pierce the trapezius."1.26Relieving pain with nerve blocks. ( Carron, H, 1978)

Research

Studies (120)

TimeframeStudies, this research(%)All Research%
pre-199060 (50.00)18.7374
1990's27 (22.50)18.2507
2000's7 (5.83)29.6817
2010's24 (20.00)24.3611
2020's2 (1.67)2.80

Authors

AuthorsStudies
Chae, JS1
Kim, WJ1
Choi, SH1
Kolodge, G1
Gold, LS1
Jarvik, JG4
Turner, J1
Hansen, RN1
Heagerty, PJ4
Suri, P4
Friedly, J1
Boelens, OB1
Maatman, RC1
Scheltinga, MR1
van Laarhoven, K1
Roumen, RM1
Castro, E1
Dent, D1
Alves, JC1
Dos Santos, AM1
Fernandes, ÂD1
Friedly, JL3
Comstock, BA2
Bauer, Z3
Rothman, MS1
Hansen, R1
Avins, AL1
Nedeljkovic, SS3
Nerenz, DR1
Akuthota, V1
Palmer, TR1
Furman, MB1
Johnson, SC1
Miskin, N1
Gaviola, GC1
Ghazikhanian, V1
Mandell, JC1
da Cruz, CM1
Antunes, F1
Tagowski, M1
Lewandowski, Z1
Hodler, J1
Spiegel, T1
Goerres, GW1
Mooney, JJ1
Pagel, PS1
Kundu, A1
Gao, W1
Ren, Y1
Cui, GX1
Pashova, H2
Turner, JA2
Annaswamy, TM2
Wasan, AD2
Lee, JH1
Lee, SH2
Wang, B1
Guo, H1
Yuan, L1
Huang, D1
Zhang, H1
Hao, D1
Manchikanti, L2
Kaye, AD1
Hirsch, JA1
Ferrara, PE1
Ronconi, G1
Viscito, R1
Pascuzzo, R1
Rosulescu, E1
Ljoka, C1
Maggi, L1
Ferriero, G1
Foti, C1
Baliki, MN2
Geha, PY1
Jabakhanji, R1
Harden, N1
Schnitzer, TJ1
Apkarian, AV2
Venmans, A1
Klazen, CA1
Lohle, PN1
van Rooij, WJ1
Buchanan, DD1
J MacIvor, F1
Nahm, FS1
Lee, CJ1
Kim, TH1
Sim, WS1
Cho, HS1
Park, SY1
Kim, YC1
Lee, SC1
Wilson, MJ1
Moore, PA1
Shennan, A1
Lancashire, RJ1
MacArthur, C1
Abbasi, A1
Roque-Dang, CM1
Malhotra, G1
Hashmi, JA1
Huang, L1
Parks, EL1
Chanda, ML1
Schnitzer, T1
Grigoras, A1
Lee, P1
Sattar, F1
Shorten, G1
SUETTINGER, H1
SULLIVAN, CR1
SYMMONDS, RE1
LINDHOLM, R1
SALENIUS, P1
ZOHN, DA1
FRANZ, A1
Boswell, MV1
Singh, V1
Pampati, V1
Damron, KS1
Beyer, CD1
Neafsey, PJ1
Podder, S1
Kumar, N1
Yaddanapudi, LN1
Chari, P1
Dunn, WR1
Cordasco, FA1
Flynn, E1
Jules, K1
Gordon, M1
Liguori, G1
Rooney, BA1
Crown, ED1
Hulsebosch, CE1
McAdoo, DJ1
Botwin, K1
Brown, LA1
Fishman, M1
Rao, S1
Naeim, F2
Froetscher, L2
Hirschberg, GG2
Warfield, CA4
Stein, JM1
Santiesteban, AJ1
Raymond, J1
Dumas, JM1
Bourne, IH2
Thakkar, CJ1
Maniar, AU1
Laheri, V1
Gandhi, M1
Talwalkar, C1
Lippitt, AB1
Magill, CD1
Arct, W1
Carrera, GF3
Mathur, JG1
Hauswirth, R1
Michot, F1
Brattebø, G1
Wisborg, T1
Rodt, SA1
Røste, I1
Pinczower, GR1
Chadwick, HS1
Woodland, R1
Lowmiller, M1
Crabb, IJ1
Allan, L1
Stolker, RJ1
Vervest, AC1
Groen, GJ1
Stanley, D1
Stockley, I1
Davies, GK1
Getty, CJ1
Stevens, RA1
Urmey, WF1
Urquhart, BL1
Kao, TC1
Pollock, JE1
Neal, JM1
Stephenson, CA1
Wiley, CE1
Hong, Y1
O'Grady, T1
Lopresti, D1
Carlsson, C1
Dolan, AL1
Ryan, PJ1
Arden, NK1
Stratton, R1
Wedley, JR1
Hamann, W1
Fogelman, I1
Gibson, T1
Wang, YL2
Tan, PP1
Yang, CH1
Tsai, SC1
Chung, HS1
Martínez-Bourio, R1
Arzuaga, M1
Quintana, JM1
Aguilera, L1
Aguirre, J1
Sáez-Eguilaz, JL1
Arízaga, A1
Liguori, GA1
Zayas, VM1
Chisholm, MF1
Dahlgren, N1
Corbey, MP1
Bach, AB1
deJong, RH1
Salmela, L1
Aromaa, U1
Axelrod, EH1
Alexander, GD1
Brown, M1
Schork, MA1
Flaatten, H1
Berg, CM1
Brekke, S1
Holmaas, G1
Natvik, C1
Varughese, K1
Weihmayr, T1
Hsieh, JR1
Hui, YL1
Yu, CC1
Lau, WM1
Ng, YT1
Finneson, BE1
Krempen, JF1
Smith, BS1
DeFreest, LJ1
Mooney, V1
Baheti, DK1
Wilber, MC1
Moir, DD1
Slater, PJ1
Thorburn, J1
McLaren, R1
Moodie, J1
Banerjee, T1
Pittman, HH1
Arnhoff, FN1
Triplett, HB1
Pokorney, B1
Benini, A1
Carron, H1
Yates, DW1
Bourne, J1
Culling, RD1
Rice, JH1
Jackson, RP1
Hynson, JM1
Sessler, DI1
Glosten, B1
Ramm, S1
Ebeling, L1
Schmitz, H1
Carette, S1
Marcoux, S1
Truchon, R1
Grondin, C1
Gagnon, J1
Allard, Y1
Latulippe, M1
Collée, G1
Dijkmans, BA1
Vandenbroucke, JP1
Cats, A1
Layton, AM1
Cotterill, JA1
Ongley, MJ1
Klein, RG1
Dorman, TA1
Eek, BC1
Hubert, LJ1
Levy, L1
Randel, GI1
Pandit, SK1
Garvey, TA1
Marks, MR1
Wiesel, SW1
Marks, R1
Berger, JJ1
Pyles, ST1
Saga-Rumley, SA1
Sonne, M1
Christensen, K1
Hansen, SE1
Jensen, EM1
Vadeboncoeur, R1
Milette, PC1
Nistor, MM1
Lewinnek, GE1
Crews, DA1
Murtagh, FR1
Cherry, DA1
Gourlay, GK1
McLachlan, M1
Cousins, MJ1
Biliński, P1
Wall, A1
Swerdlow, M2
Sayle-Creer, WS1
Kraus, H1
Brothers, MA1
Finlayson, DC1
Dawkins, CJ1
Sayle-Creer, W1
Cho, KO1
Durand, H1
Masson, V1
Matte, R1
Plante, JM1
de Morsier, G1
Warr, AC1
Wilkinson, JA1
Burn, JM3
Langdon, L2
Guyer, PB1
Huraj, E1
Látal, J1
Horský, I1
Leedy, RF1
Colon, VF1
Phillips, OC1
Ebner, H1
Nelson, AT1
Black, MH1

Clinical Trials (14)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Multicenter Randomized Controlled Trial of Epidural Steroid Injections for Spinal Stenosis in Persons 50 and Older[NCT01238536]Phase 4400 participants (Actual)Interventional2011-04-30Completed
Using Inflammatory Biomarkers and EMG Results to Predict Epidural Injection Response in Patients Diagnosed With Lumbar Stenosis[NCT03511053]11 participants (Actual)Interventional2017-12-19Completed
Radiofrequency Ablation of the Medial Branch Nerve as a Novel Treatment for Posterior Element Pain From Vertebral Compression Fractures[NCT03651804]Phase 460 participants (Anticipated)Interventional2019-04-10Suspended (stopped due to Difficulty recruiting members)
Brain Imaging of Lidoderm for Chronic Back Pain[NCT01515540]Phase 438 participants (Actual)Interventional2004-01-31Completed
The Study of Perioperative Intravenous Infusion of Lidocaine on Postoperative Analgesia in Patients Undergoing Single-port Thoracoscopic[NCT04043624]Phase 480 participants (Anticipated)Interventional2019-08-01Recruiting
Mind-body Treatments for Chronic Back Pain[NCT03294148]151 participants (Actual)Interventional2017-08-07Completed
Randomized, Placebo-controlled Crossover Trial Evaluating Topical Lidocaine Patch(es) for Mechanical Neck Pain.[NCT04378959]76 participants (Actual)Interventional2021-02-01Completed
A Randomized, Controlled, Double-Blind Trial of 3 Local Anesthetics for Spinal Anesthesia in Primary Total Hip Arthroplasty to Compare the Percentage of Patients in Each Group With Early Ambulation[NCT03948386]Phase 4159 participants (Actual)Interventional2019-05-13Completed
Prognostic Factors of Efficacy in Corticoid and Anesthetic Joint Infiltration for the Treatment of Patients With Low Back Pain Secondary to Zygapophyseal Osteoarthritis: a Prospective Cohort Study[NCT03304730]147 participants (Anticipated)Observational2017-09-01Recruiting
The Efficacy of Prolotherapy in Osteoarthritic Knee Pain[NCT00085722]Phase 1/Phase 298 participants (Actual)Interventional2004-07-31Completed
Double-blind, Prospective Comparison of Medications Used in Trigger Point Injections - Ketorolac, Lidocaine, or Dexamethasone[NCT03028012]Phase 410 participants (Actual)Interventional2017-05-02Terminated (stopped due to Poor enrollment.)
Dry Needling Effectiveness of Patients on Break Anterior Cruciate Ligament. Single-Blind Randomized Clinical Trial.[NCT02699411]40 participants (Anticipated)Interventional2016-02-29Recruiting
A Randomized Controlled Study Comparing Trigger Point Injections With 1% Lidocaine Versus 5% Lidocaine Patch for Myofascial Pain in the Emergency Department[NCT05151510]Phase 4110 participants (Anticipated)Interventional2021-11-01Recruiting
Sphenopalatine Ganglion Block to Treat Shoulder Pain After Laparoscopic Surgery: A Prospective, Randomized, Double Blinded Trial[NCT04101019]76 participants (Anticipated)Interventional2019-09-30Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Leg Pain NRS

Leg Pain NRS 0-10 scale (NCT01238536)
Timeframe: 12 months

Interventionunits on a scale (Mean)
Epidural Steroid Injection4.7
Epidural Local Anesthetic Injection4.3

Pain Numeric Rating Scale

Leg Pain NRS is a second primary outcome at 6 weeks We measured leg pain using a 0-10 pain NRS (0=no pain and 10=worst pain imaginable) assessing average pain over the past week. (NCT01238536)
Timeframe: 6 weeks

Interventionunits on a scale (Mean)
Epidural Steroid Injection4.4
Epidural Local Anesthetic Injection4.6

Roland Morris

The primary outcome measure will be back specific functional status, measured by the Roland Scale at 6 weeks. The RDQ is a back pain specific functional status questionnaire adapted from the Sickness Impact Profile (SIP). The RDQ consists of 24 yes/no items, which represent common dysfunctions in daily activities experienced by subjects with low back pain. A single unweighted score is derived by summing the 24 items, with higher scores indicating worse function with 0 (no disability) to 24 (maximum disability). Our primary analysis will be a simple 2-group comparison of the mean Roland score as an evaluation of the short-term efficacy of epidural steroid injection. (NCT01238536)
Timeframe: 6 weeks

Interventionunits on a scale (Mean)
Epidural Steroid Injection11.8
Epidural Local Anesthetic Injection12.5

Roland Morris Disability Questionnaire (RDQ)

The RDQ is a back pain specific functional status questionnaire adapted from the Sickness Impact Profile (SIP). The RDQ consists of 24 yes/no items, which represent common dysfunctions in daily activities experienced by subjects with low back pain. A single unweighted score is derived by summing the 24 items, with higher scores indicating worse function with 0 (no disability) to 24 (maximum disability). Our primary analysis will be a simple 2-group comparison of the mean Roland score as an evaluation of the short-term efficacy of epidural steroid injection. (NCT01238536)
Timeframe: 12 months

Interventionunits on a scale (Mean)
Epidural Steroid Injection12.0
Epidural Local Anesthetic Injection11.5

Pain Disability Questionnaire

Measures how pain is affecting the patients lifestyle on a scale from 0 to 10 as defined by each question. The questionnaire contains 15 questions that each range on a scale form 0 to 10. The total score of the questionnaire ranges from 0 to 150. Lower values represent a better outcome. (NCT03511053)
Timeframe: Change between baseline, 1 month and 2 months post injection

Interventionscore on a scale (Mean)
Average at baselineAverage at 1 monthAverage at 2 monthsAverage at 1 month changeAverage at 2 month change
All Participants77.553.364.327.316.2

Swiss Spinal Stenosis Questionnaire

Measures how pain due to spinal stenosis is effected the patient based on quality of life/pain questions and satisfaction questions for months 1 and 2 (no scales are used) SSSQ scores are reported in percentages 0-100%, higher scores indicate worse outcomes. (NCT03511053)
Timeframe: Change between baseline, 1 month and 2 months post injection

InterventionPercentage (Mean)
Average at baselineAverage at 1 monthAverage at 2 monthsAverage at 1 month changeAverage at 2 month change
All Participants64.153.253.511.710.3

Visual Analogue Scale

Number rating of back/leg pain from 0 to 10, 0 being no pain/discomfort, 10 being extreme pain/discomfort (NCT03511053)
Timeframe: Change between baseline, 1 month and 2 months post injection

Interventionscore on a scale (Mean)
Average at baselineAverage at 1 monthAverage at 2 monthsAverage 1 month changeAverage 2 month change
All Participants6.25.05.00.81

"Pain Intensity on a Visual Analog Scale (VAS) The Scale Had Values From 0-100, Where 0 Represents no Pain and 100 Was the Worst Pain Imaginable."

"the primary hypothesis was that the lidoderm 5% patch was expected to decrease pain intensity post treatment greater than placebo patch.~A lower value on the 0-100 scale is considered to represent less pain. Higher values represent more pain. Greater than 20%-30% decrease in pain is considered clinically meaningful." (NCT01515540)
Timeframe: 2 weeks

Interventionpeak pain intensity (Mean)
Lidocaine51.0
Control51.6

Brief Pain Inventory-Short Form (BPI-SF)

1-week average pain intensity, 0 - 10 numerical rating scale, where a higher score indicates more pain. (NCT03294148)
Timeframe: At post-treatment fMRI session, approximately 1 month after randomization

Interventionunits on a scale (Mean)
Pain Reprocessing Therapy (PRT)1.18
Placebo2.84
Usual Care3.13

Negative Affect Scale Short Form (PANAS-SF)

Questionnaire to rate negative affect, scores range from 5 - 25, with a higher score meaning a stronger negative affect (NCT03294148)
Timeframe: At post-treatment fMRI session, approximately 1 month after randomization

Interventionscore on a scale (Mean)
Pain Reprocessing Therapy (PRT)8.30
Placebo7.70
Usual Care8.19

Oswestry Disability Index

Back pain disability questionnaire measured on a scale of 0-100. A higher score indicates a higher severity of disability. (NCT03294148)
Timeframe: At post-treatment fMRI session, approximately 1 month after randomization

Interventionscore on a scale (Mean)
Pain Reprocessing Therapy (PRT)10.14
Placebo19.00
Usual Care20.68

Pain Catastrophizing Questionnaire (PCS)

Questionnaire used to help quantify an individual's pain experience. Measured 0-52. A higher score means a higher level of catastrophizing. (NCT03294148)
Timeframe: At post-treatment fMRI session, approximately 1 month after randomization

Interventionscore on a scale (Mean)
Pain Reprocessing Therapy (PRT)8.30
Placebo7.70
Usual Care8.19

Patient Global Impression of Change (PGIC)

Post-treatment-only outcome measure depicting a patient's subjective rating of overall improvement. Score ranges from 1-7 with a higher score indicating a higher level of change and improvement (NCT03294148)
Timeframe: At post-treatment fMRI session, approximately 1 month after randomization

Interventionscore on a scale (Mean)
Pain Reprocessing Therapy (PRT)6.14
Placebo3.61
Usual Care2.06

Positive Affect Scale Short Form (PANAS-SF)

Questionnaire to rate positive affect, scores range from 5 - 25, a higher score means stronger affect (NCT03294148)
Timeframe: At post-treatment fMRI session, approximately 1 month after randomization

Interventionscore on a scale (Mean)
Pain Reprocessing Therapy (PRT)17.89
Placebo15.20
Usual Care14.98

PROMIS Anger

Questionnaire measuring anger (5 items) with a score range of 5-25. Higher scores indicate a higher severity of anger. (NCT03294148)
Timeframe: At post-treatment fMRI session, approximately 1 month after randomization

Interventionscore on a scale (Mean)
Pain Reprocessing Therapy (PRT)9.52
Placebo9.89
Usual Care10.45

PROMIS Anxiety

Questionnaire measuring anxiety (8 items). Scores range from 8-40 with a higher score meaning more severe levels of fear, anxious misery, hyperarousal, and somatic symptoms related to arousal. (NCT03294148)
Timeframe: At post-treatment fMRI session, approximately 1 month after randomization

Interventionscore on a scale (Mean)
Pain Reprocessing Therapy (PRT)15.02
Placebo13.89
Usual Care14.11

PROMIS Sleep

Questionnaire measuring sleep disturbance (8 items). Scores range from 8-40. Higher scores indicate higher levels of sleep disturbance (NCT03294148)
Timeframe: At post-treatment fMRI session, approximately 1 month after randomization

Interventionscore on a scale (Mean)
Pain Reprocessing Therapy (PRT)17.73
Placebo20.50
Usual Care20.89

PROMIS- Depression

Questionnaire measuring depression (8 items). Scores range from 8-32. A higher score indicates higher levels of depressive symptoms (NCT03294148)
Timeframe: At post-treatment fMRI session, approximately 1 month after randomization

Interventionscore on a scale (Mean)
Pain Reprocessing Therapy (PRT)12.23
Placebo11.75
Usual Care11.81

Tampa Scale of Kinesiophobia (TSK)

Questionnaire used to assess the subjective rating of kinesiophobia or fear of movement. Scores range from 11-44 with higher scores indicating greater fear of pain, movement, and injury. (NCT03294148)
Timeframe: At post-treatment fMRI session, approximately 1 month after randomization

Interventionscore on a scale (Mean)
Pain Reprocessing Therapy (PRT)16.41
Placebo22.16
Usual Care22.51

Timeline Follow-Back Measure for Alcohol (TLFB)

Questionnaire used to assess daily drinking (number of drinks consumed over past two weeks) (NCT03294148)
Timeframe: At post-treatment fMRI session, approximately 1 month after randomization

InterventionDrinks (Mean)
Pain Reprocessing Therapy (PRT)11.63
Placebo12.88
Usual Care8.02

Timeline Follow-Back Measure for Cannabis (TLFB)

Questionnaire used to assess daily cannabis use (number of grams consumed over past two weeks) (NCT03294148)
Timeframe: At post-treatment fMRI session, approximately 1 month after randomization

InterventionGrams of cannabis (Mean)
Pain Reprocessing Therapy (PRT)6.76
Placebo3.31
Usual Care1.49

Timeline Follow-Back Measure for Opioid Use (TLFB)

Questionnaire used to assess daily opioid use (number of pills consumed over past two weeks) (NCT03294148)
Timeframe: At post-treatment fMRI session, approximately 1 month after randomization

InterventionOpioid pills (Mean)
Pain Reprocessing Therapy (PRT)1.29
Placebo0.36
Usual Care1.77

Treatment Satisfaction Questionnaire

Post-treatment-only outcome measure depicting the patient's satisfaction with the treatment. Measured 0 - 100. A higher score means higher satisfaction with treatment/ (NCT03294148)
Timeframe: At post-treatment fMRI session, approximately 1 month after randomization

Interventionscore on a scale (Mean)
Pain Reprocessing Therapy (PRT)92.40
Placebo57.61
Usual Care36.86

Hospital Stay

length of hospital stay (NCT03948386)
Timeframe: hospital stay (0-3 days)

Interventionhours (Median)
Isobaric Bupivacaine26
Hyperbaric Bupivacaine26
Isobaric Mepivacaine22

Number of Patients With Dizziness Events

number of patients with dizziness when transitioning from lying down to sitting or standing (NCT03948386)
Timeframe: Postoperative day 2

InterventionParticipants (Count of Participants)
Isobaric Bupivacaine11
Hyperbaric Bupivacaine7
Isobaric Mepivacaine9

Number of Patients With Transient Neurological Symptoms (TNS)

Number of patients with TNS events occurring. Transient neurological symptoms were defined as new onset of back, buttock, or thigh pain occurring after spinal anesthesia. (NCT03948386)
Timeframe: Postoperative days 0-2

InterventionParticipants (Count of Participants)
Isobaric Bupivacaine2
Hyperbaric Bupivacaine6
Isobaric Mepivacaine5

Number of Patients With Urinary Retention Events

number of patients with inability to urinate within 8 hours of surgery OR a report of distended or painful bladder occurring on postoperative day 0 or 1, either by patient report or on palpation by nursing (NCT03948386)
Timeframe: postoperative day 1

InterventionParticipants (Count of Participants)
Isobaric Bupivacaine6
Hyperbaric Bupivacaine8
Isobaric Mepivacaine5

Percentage Ambulating Early After Spinal Anesthesia

Is there a difference between isobaric mepivacaine, hyperbaric bupivacaine, and isobaric bupivacaine when used for spinal anesthesia in primary total hip replacement in percentage of patients that can ambulate within 3.5 hours after spinal anesthesia? (NCT03948386)
Timeframe: 3.5 hours

InterventionParticipants (Count of Participants)
Isobaric Bupivacaine9
Hyperbaric Bupivacaine20
Isobaric Mepivacaine35

Return of Motor Function of the Thigh and Lower Leg

time to return of motor function of the thigh and lower leg (NCT03948386)
Timeframe: Postoperative day 0 (day of surgery)

Interventionminutes (Median)
Isobaric Bupivacaine148
Hyperbaric Bupivacaine123
Isobaric Mepivacaine109

Number of Participants With a Responder Rate Greater Than 50% on the Numeric Rating Pain Scale (NRS) Improvement

Participants in this study underwent TPIs by the following method. The needle was inserted into the trigger point with the goal of eliciting a local twitch responses(LTRs). When a LTR was obtained, 0.1mL of randomized drug was injected into that location within the muscle. This was repeated until LTRs disappeared, or 1.0mL had been injected, whichever came first. This was performed in a similar manner for all affected muscles, up to a maximum of 2mL. Participants self-report their brief pain inventory at each of their injections (up to four subsequent injections) based off of the standardized Numeric Rating pain Scale (NRS). The NRS is nationally recognized numeric scale from zero to ten, with zero being an example of no pain, one to three would demonstrate mild pain, four to six would be moderate pain, seven to nine would be severe pain and a ten would be the worst pain possible. Improvement in BPI was determined if their NRS score went down with each injection(s). (NCT03028012)
Timeframe: Pre-Post Injections Up to Three Months

InterventionParticipants (Count of Participants)
Ketorolac1
Lidocaine0
Dexamethasone0

Brief Pain Inventory (BPI) - Modified

The BPI was evaluated on a scale from 0-10. Zero would mean no interference and 10 would be calculated at complete interferences. We used a 7-point questionnaire about pain. All scores were calculated at baseline and three months. (NCT03028012)
Timeframe: Baseline and Three Months

Interventionscore on a scale (Number)
Participant Number #3 at BaselineParticipant Number #3 at 3 MonthsParticipant Number #8 at BaselineParticipant #8 at 3 Months
Ketorolac8353

Numeric Rating Pain Scale (NRS) at Baseline and Three Months.

TPI were treated with a needle inserted into the trigger point with the goal of eliciting a local twitch responses(LTRs). When a LTR was obtained, 0.1mL of randomized drug was injected into that location within the muscle. This was repeated until LTRs disappeared, or 1.0mL had been injected, whichever came first. Such was performed in a similar manner for all affected muscles, up to a maximum of 2mL. Participants self-report their brief pain inventory at each of their injections (up to four subsequent injections) based off of the standardized Numeric Rating pain Scale (NRS). The NRS is nationally recognized numeric scale from zero to ten, with zero being an example of no pain,one to three would demonstrate mild pain, four to six would be moderate pain, seven to nine would be severe pain and a ten would be the worst pain possible. Improvement in BPI was determined if their NRS score went down with each injection(s). (NCT03028012)
Timeframe: Pre-Injection and Three Month Post Injection(s)

Interventionscore on a scale (Number)
Participant Number 3 at BaselineParticipant Number 3 at 3 MonthsParticipant Number 8 at BaselineParticipant Number 8 at 3 Months
Ketorolac8353

Reviews

5 reviews available for lidocaine and Back Ache

ArticleYear
Physical Medicine and Rehabilitation Role on Notalgia Paresthetica: Case Report and Treatment Review.
    American journal of physical medicine & rehabilitation, 2018, Volume: 97, Issue:12

    Topics: Adult; Anesthetics, Local; Back Pain; Exercise Therapy; Female; Humans; Hyperpigmentation; Lidocaine

2018
Persistent hiccups after interventional pain procedures: a case series and review.
    PM & R : the journal of injury, function, and rehabilitation, 2012, Volume: 4, Issue:2

    Topics: Adult; Back Pain; Betamethasone; Chronic Pain; Dexamethasone; Hiccup; Humans; Injections, Spinal; Li

2012
Patching pain with lidocaine: new uses for the lidocaine 5% patch.
    Home healthcare nurse, 2004, Volume: 22, Issue:8

    Topics: Administration, Cutaneous; Anesthetics, Local; Back Pain; Humans; Lidocaine; Neuralgia; Osteoarthrit

2004
The facet syndrome. Myth or reality?
    Clinical orthopaedics and related research, 1992, Issue:279

    Topics: Adult; Anesthesia, Conduction; Back Pain; Biomechanical Phenomena; Female; Humans; Injections, Intra

1992
An analysis of the complications of extradural and caudal block.
    Anaesthesia, 1969, Volume: 24, Issue:4

    Topics: Adult; Aged; Anesthesia, Spinal; Back Pain; Blood Pressure; Catheterization; Dura Mater; Epinephrine

1969

Trials

31 trials available for lidocaine and Back Ache

ArticleYear
Effects of Local Anesthetics With or Without Steroids in High-Volume Transforaminal Epidural Blocks for Lumbar Disc Herniation: A Randomized, Double-Blind, Controlled Trial.
    Journal of Korean medical science, 2022, May-02, Volume: 37, Issue:17

    Topics: Anesthetics, Local; Back Pain; Humans; Injections, Epidural; Intervertebral Disc Displacement; Lidoc

2022
Treatment With Opioids Is Not Associated With Poor Outcomes Among Older Adults With Lumbar Spinal Stenosis Receiving Epidural Injections.
    Spine, 2023, Apr-01, Volume: 48, Issue:7

    Topics: Aged; Analgesics, Opioid; Anesthetics, Local; Back Pain; Humans; Injections, Epidural; Lidocaine; Lu

2023
A comparison of transdermal over-the-counter lidocaine 3.6% menthol 1.25%, Rx lidocaine 5% and placebo for back pain and arthritis.
    Pain management, 2017, Volume: 7, Issue:6

    Topics: Administration, Cutaneous; Anesthetics, Local; Arthritis; Back Pain; Double-Blind Method; Drug Combi

2017
Evaluation of the effect of mesotherapy in the management of back pain in police working dog.
    Veterinary anaesthesia and analgesia, 2018, Volume: 45, Issue:1

    Topics: Analgesics; Animals; Back Pain; Carbazoles; Colchicine; Dexamethasone; Dog Diseases; Dogs; Drug Ther

2018
Systemic effects of epidural steroid injections for spinal stenosis.
    Pain, 2018, Volume: 159, Issue:5

    Topics: Adrenal Cortex Hormones; Aged; Aged, 80 and over; Anesthetics, Local; Back Pain; Betamethasone; Dexa

2018
Dexamethasone added to local lidocaine for infiltration along the spinal-epidural needle pathway decreases incidence and severity of backache after gynecological surgery.
    Medical science monitor : international medical journal of experimental and clinical research, 2015, Mar-18, Volume: 21

    Topics: Adult; Anesthesia, Epidural; Anesthesia, Spinal; Anesthetics, Local; Back Pain; Dexamethasone; Femal

2015
A prospective randomized controlled study comparing the pain relief in patients with osteoporotic vertebral compression fractures with the use of vertebroplasty or facet blocking.
    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2016, Volume: 25, Issue:11

    Topics: Aged; Aged, 80 and over; Anesthetics, Local; Back Pain; Disability Evaluation; Female; Fractures, Co

2016
Percutaneous vertebroplasty and procedural pain.
    AJNR. American journal of neuroradiology, 2010, Volume: 31, Issue:5

    Topics: Aged; Back Pain; Female; Humans; Lidocaine; Male; Pain Measurement; Treatment Outcome; Vertebroplast

2010
Long-term effects of epidural analgesia in labor: a randomized controlled trial comparing high dose with two mobile techniques.
    Birth (Berkeley, Calif.), 2011, Volume: 38, Issue:2

    Topics: Adult; Analgesia, Obstetrical; Anesthesia, Epidural; Anesthetics, Local; Back Pain; Bupivacaine; Fec

2011
Lidocaine patch (5%) is no more potent than placebo in treating chronic back pain when tested in a randomised double blind placebo controlled brain imaging study.
    Molecular pain, 2012, Apr-24, Volume: 8

    Topics: Back Pain; Brain; Brain Mapping; Chronic Pain; Double-Blind Method; Female; Humans; Lidocaine; Magne

2012
Lidocaine patch (5%) is no more potent than placebo in treating chronic back pain when tested in a randomised double blind placebo controlled brain imaging study.
    Molecular pain, 2012, Apr-24, Volume: 8

    Topics: Back Pain; Brain; Brain Mapping; Chronic Pain; Double-Blind Method; Female; Humans; Lidocaine; Magne

2012
Lidocaine patch (5%) is no more potent than placebo in treating chronic back pain when tested in a randomised double blind placebo controlled brain imaging study.
    Molecular pain, 2012, Apr-24, Volume: 8

    Topics: Back Pain; Brain; Brain Mapping; Chronic Pain; Double-Blind Method; Female; Humans; Lidocaine; Magne

2012
Lidocaine patch (5%) is no more potent than placebo in treating chronic back pain when tested in a randomised double blind placebo controlled brain imaging study.
    Molecular pain, 2012, Apr-24, Volume: 8

    Topics: Back Pain; Brain; Brain Mapping; Chronic Pain; Double-Blind Method; Female; Humans; Lidocaine; Magne

2012
Perioperative intravenous lidocaine decreases the incidence of persistent pain after breast surgery.
    The Clinical journal of pain, 2012, Volume: 28, Issue:7

    Topics: Administration, Intravenous; Adult; Aged; Anesthetics, Local; Back Pain; Breast Neoplasms; Chronic D

2012
Paramedian lumbar epidural catheter insertion with patients in the sitting position is equally successful in the flexed and unflexed spine.
    Anesthesia and analgesia, 2004, Volume: 99, Issue:6

    Topics: Adult; Anesthesia, Epidural; Anesthetics, Local; Back Pain; Catheterization; Epidural Space; Female;

2004
A prospective randomized comparison of spinal versus local anesthesia with propofol infusion for knee arthroscopy.
    Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 2006, Volume: 22, Issue:5

    Topics: Anesthesia Recovery Period; Anesthesia, Local; Anesthesia, Spinal; Anesthetics, Combined; Anesthetic

2006
Treatment of chronic back pain. Comparing corticosteroid-lignocaine injections with lignocaine alone.
    The Practitioner, 1984, Volume: 228, Issue:1389

    Topics: Adult; Back Pain; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Injections, Intramusc

1984
Is the pencil point spinal needle a better choice in younger patients? A comparison of 24G Sprotte with 27G Quincke needles in an unselected group of general surgical patients below 46 years of age.
    Acta anaesthesiologica Scandinavica, 1995, Volume: 39, Issue:4

    Topics: Adolescent; Adult; Anesthesia, Spinal; Back Pain; Bupivacaine; Equipment Design; Female; Headache; H

1995
A prospective study of diagnostic epidural blockade in the assessment of chronic back and leg pain.
    Journal of spinal disorders, 1993, Volume: 6, Issue:3

    Topics: Adult; Aged; Anesthesia, Epidural; Back Pain; Diagnosis, Differential; Female; Humans; Leg; Lidocain

1993
Back pain after epidural anesthesia with chloroprocaine.
    Anesthesiology, 1993, Volume: 78, Issue:3

    Topics: Adolescent; Adult; Aged; Analgesia, Epidural; Anesthesia, Epidural; Anesthetics, Local; Back Pain; D

1993
Prospective study of the incidence of transient radicular irritation in patients undergoing spinal anesthesia.
    Anesthesiology, 1996, Volume: 84, Issue:6

    Topics: Adult; Aged; Anesthesia, Spinal; Anesthetics, Local; Back Pain; Bupivacaine; Double-Blind Method; Fe

1996
Epidural dexamethasone reduces the incidence of backache after lumbar epidural anesthesia.
    Anesthesia and analgesia, 1997, Volume: 84, Issue:2

    Topics: Adult; Anesthesia, Epidural; Anesthetics, Local; Anti-Inflammatory Agents; Back Pain; Dexamethasone;

1997
Incidence of transient neurologic symptoms after hyperbaric subarachnoid anesthesia with 5% lidocaine and 5% prilocaine.
    Anesthesiology, 1998, Volume: 88, Issue:3

    Topics: Adult; Aged; Anesthesia, Spinal; Atmospheric Pressure; Back Pain; Female; Humans; Lidocaine; Male; M

1998
Transient neurologic symptoms after spinal anesthesia with mepivacaine and lidocaine.
    Anesthesiology, 1998, Volume: 88, Issue:3

    Topics: Adult; Ambulatory Surgical Procedures; Anesthesia, Spinal; Arthroscopy; Back Pain; Double-Blind Meth

1998
Transient radicular irritation after spinal anesthesia induced with hyperbaric solutions of cerebrospinal fluid-diluted lidocaine 50 mg/ml or mepivacaine 40 mg/ml or bupivacaine 5 mg/ml.
    Acta anaesthesiologica Scandinavica, 1998, Volume: 42, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Spinal; Anesthetics, Local; Back Pain; Bupivacaine; Cere

1998
Local supplementation of ketoprofen reduces the incidence of low back pain after lumbar epidural anesthesia.
    Changgeng yi xue za zhi, 1999, Volume: 22, Issue:3

    Topics: Adult; Aged; Anesthesia, Epidural; Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Female; Hemor

1999
Extradural analgesia in obstetrics: a controlled trial of carbonated lignocaine and bupivacaine hydrochloride with or without adrenaline.
    British journal of anaesthesia, 1976, Volume: 48, Issue:2

    Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Back Pain; Bupivacaine; Epinephrine; Female; Headache

1976
A controlled trial of corticosteroid injections into facet joints for chronic low back pain.
    The New England journal of medicine, 1991, Oct-03, Volume: 325, Issue:14

    Topics: Adrenal Cortex Hormones; Adult; Back Pain; Female; Follow-Up Studies; Humans; Injections, Intra-Arti

1991
Iliac crest pain syndrome in low back pain. A double blind, randomized study of local injection therapy.
    The Journal of rheumatology, 1991, Volume: 18, Issue:7

    Topics: Adult; Back Pain; Double-Blind Method; Female; Humans; Ilium; Injections; Lidocaine; Lumbosacral Reg

1991
A new approach to the treatment of chronic low back pain.
    Lancet (London, England), 1987, Jul-18, Volume: 2, Issue:8551

    Topics: Adult; Aged; Back Pain; Clinical Trials as Topic; Double-Blind Method; Female; Follow-Up Studies; Hu

1987
A prospective, randomized, double-blind evaluation of trigger-point injection therapy for low-back pain.
    Spine, 1989, Volume: 14, Issue:9

    Topics: Acupuncture Therapy; Adult; Anti-Inflammatory Agents; Back Pain; Double-Blind Method; Ethyl Chloride

1989
A prospective, randomized, double-blind evaluation of trigger-point injection therapy for low-back pain.
    Spine, 1989, Volume: 14, Issue:9

    Topics: Acupuncture Therapy; Adult; Anti-Inflammatory Agents; Back Pain; Double-Blind Method; Ethyl Chloride

1989
A prospective, randomized, double-blind evaluation of trigger-point injection therapy for low-back pain.
    Spine, 1989, Volume: 14, Issue:9

    Topics: Acupuncture Therapy; Adult; Anti-Inflammatory Agents; Back Pain; Double-Blind Method; Ethyl Chloride

1989
A prospective, randomized, double-blind evaluation of trigger-point injection therapy for low-back pain.
    Spine, 1989, Volume: 14, Issue:9

    Topics: Acupuncture Therapy; Adult; Anti-Inflammatory Agents; Back Pain; Double-Blind Method; Ethyl Chloride

1989
A prospective, randomized, double-blind evaluation of trigger-point injection therapy for low-back pain.
    Spine, 1989, Volume: 14, Issue:9

    Topics: Acupuncture Therapy; Adult; Anti-Inflammatory Agents; Back Pain; Double-Blind Method; Ethyl Chloride

1989
A prospective, randomized, double-blind evaluation of trigger-point injection therapy for low-back pain.
    Spine, 1989, Volume: 14, Issue:9

    Topics: Acupuncture Therapy; Adult; Anti-Inflammatory Agents; Back Pain; Double-Blind Method; Ethyl Chloride

1989
A prospective, randomized, double-blind evaluation of trigger-point injection therapy for low-back pain.
    Spine, 1989, Volume: 14, Issue:9

    Topics: Acupuncture Therapy; Adult; Anti-Inflammatory Agents; Back Pain; Double-Blind Method; Ethyl Chloride

1989
A prospective, randomized, double-blind evaluation of trigger-point injection therapy for low-back pain.
    Spine, 1989, Volume: 14, Issue:9

    Topics: Acupuncture Therapy; Adult; Anti-Inflammatory Agents; Back Pain; Double-Blind Method; Ethyl Chloride

1989
A prospective, randomized, double-blind evaluation of trigger-point injection therapy for low-back pain.
    Spine, 1989, Volume: 14, Issue:9

    Topics: Acupuncture Therapy; Adult; Anti-Inflammatory Agents; Back Pain; Double-Blind Method; Ethyl Chloride

1989
Injection of steroids and local anaesthetics as therapy for low-back pain.
    Scandinavian journal of rheumatology, 1985, Volume: 14, Issue:4

    Topics: Anti-Inflammatory Agents; Back Pain; Clinical Trials as Topic; Double-Blind Method; Follow-Up Studie

1985
A study of extradural medication in the relief of the lumbosciatic syndrome.
    Anaesthesia, 1970, Volume: 25, Issue:3

    Topics: Anesthesia, Spinal; Back Pain; Humans; Lidocaine; Methylprednisolone; Palliative Care; Sodium Chlori

1970
The use of extradural injections in the relief of lumbo-sciatic pain.
    Anaesthesia, 1970, Volume: 25, Issue:1

    Topics: Back Pain; Dura Mater; Follow-Up Studies; Humans; Injections; Lidocaine; Methylprednisolone; Sodium

1970

Other Studies

84 other studies available for lidocaine and Back Ache

ArticleYear
Chronic Localized Back Pain Due to Posterior Cutaneous Nerve Entrapment Syndrome (POCNES): A New Diagnosis.
    Pain physician, 2017, Volume: 20, Issue:3

    Topics: Adult; Back Pain; Chronic Pain; Female; Humans; Intercostal Nerves; Lidocaine; Nerve Compression Syn

2017
Lidocaine Patches Are No Better Than Placebo for Somatic Back Pain.
    American family physician, 2017, 11-15, Volume: 96, Issue:10

    Topics: Anesthetics, Local; Back Pain; Fractures, Compression; Humans; Lidocaine; Spinal Fractures

2017
Induced lumbosacral radicular symptom referral patterns: a descriptive study.
    The spine journal : official journal of the North American Spine Society, 2019, Volume: 19, Issue:1

    Topics: Adult; Anesthetics, Local; Back Pain; Female; Humans; Injections, Epidural; Lidocaine; Lumbosacral R

2019
CT-guided transforaminal epidural steroid injections: do needle position and degree of foraminal stenosis affect the pattern of epidural flow?
    Skeletal radiology, 2018, Volume: 47, Issue:12

    Topics: Adult; Aged; Anesthetics, Local; Back Pain; Contrast Media; Female; Humans; Injections, Epidural; Io

2018
Pain reduction after lumbar epidural injections using particulate versus non-particulate steroids: intensity of the baseline pain matters.
    European radiology, 2019, Volume: 29, Issue:7

    Topics: Adult; Aged; Back Pain; Bupivacaine; Dexamethasone; Female; Glucocorticoids; Humans; Injections, Epi

2019
Safety, tolerability, and short-term efficacy of intravenous lidocaine infusions for the treatment of chronic pain in adolescents and young adults: a preliminary report.
    Pain medicine (Malden, Mass.), 2014, Volume: 15, Issue:5

    Topics: Adolescent; Anesthetics, Local; Back Pain; Chest Pain; Child; Chronic Pain; Female; Headache; Humans

2014
Short-term improvements in disability mediate patient satisfaction after epidural corticosteroid injections for symptomatic lumbar spinal stenosis.
    Spine, 2015, Sep-01, Volume: 40, Issue:17

    Topics: Aged; Aged, 80 and over; Anesthetics, Local; Back Pain; Double-Blind Method; Female; Humans; Injecti

2015
Authors' Reply to Manchikanti.
    Spine, 2016, Volume: 41, Issue:3

    Topics: Anesthetics, Local; Back Pain; Female; Humans; Lidocaine; Lumbar Vertebrae; Male; Spinal Stenosis

2016
Comparison of Clinical Efficacy Between Interlaminar and Transforaminal Epidural Injection in Patients With Axial Pain due to Cervical Disc Herniation.
    Medicine, 2016, Volume: 95, Issue:4

    Topics: Adult; Anesthetics, Local; Anti-Inflammatory Agents; Back Pain; Cervical Vertebrae; Dexamethasone; D

2016
Letters.
    Spine, 2016, Volume: 41, Issue:3

    Topics: Anesthetics, Local; Back Pain; Female; Humans; Lidocaine; Lumbar Vertebrae; Male; Spinal Stenosis

2016
Efficacy of mesotherapy using drugs versus normal saline solution in chronic spinal pain: a retrospective study.
    International journal of rehabilitation research. Internationale Zeitschrift fur Rehabilitationsforschung. Revue internationale de recherches de readaptation, 2017, Volume: 40, Issue:2

    Topics: Analgesics; Anesthetics, Local; Aspirin; Back Pain; Chronic Pain; Female; Follow-Up Studies; Humans;

2017
A preliminary fMRI study of analgesic treatment in chronic back pain and knee osteoarthritis.
    Molecular pain, 2008, Oct-25, Volume: 4

    Topics: Adult; Aged; Analgesia; Back Pain; Brain Mapping; Chronic Disease; Female; Gyrus Cinguli; Humans; Li

2008
A role for intravenous lidocaine in severe cancer-related neuropathic pain at the end-of-life.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2010, Volume: 18, Issue:7

    Topics: Aged; Anesthetics, Local; Back Pain; Bone Neoplasms; Humans; Infusions, Intravenous; Kidney Neoplasm

2010
Risk of intravascular injection in transforaminal epidural injections.
    Anaesthesia, 2010, Volume: 65, Issue:9

    Topics: Aged; Anesthetics, Local; Back Pain; Blood Vessels; Female; Fluoroscopy; Humans; Injections, Epidura

2010
[On experiences in anesthetic therapy with xylocaine].
    Die Medizinische Welt, 1962, Oct-20, Volume: 42

    Topics: Anesthetics; Back Pain; Humans; Humerus; Intervertebral Disc Displacement; Lidocaine

1962
DISK INFECTIONS AND ABDOMINAL PAIN.
    JAMA, 1964, May-18, Volume: 188

    Topics: Abdomen; Abdomen, Acute; Abdominal Pain; Back Pain; Casts, Surgical; Diagnosis, Differential; Humans

1964
CAUDAL, EPIDURAL ADMINISTRATION OF ANAESTHETICS AND CORTICOIDS IN THE TREATMENT OF LOW BACK PAIN.
    Acta orthopaedica Scandinavica, 1964, Volume: 34

    Topics: Adrenal Cortex Hormones; Anesthesia, Epidural; Anesthesia, Spinal; Anesthetics; Back Pain; Humans; I

1964
THE DIAGNOSIS AND TREATMENT OF THORACIC BACK PAIN.
    GP, 1964, Volume: 30

    Topics: Back Pain; Diagnosis; Drug Therapy; Humans; Hydrocortisone; Lidocaine; Respiratory Function Tests; T

1964
Prevalence of facet joint pain in chronic spinal pain of cervical, thoracic, and lumbar regions.
    BMC musculoskeletal disorders, 2004, May-28, Volume: 5

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Back Pain; Bupivacaine; Cervical Vertebrae; Chro

2004
Preemptive analgesia with lidocaine prevents Failed Back Surgery Syndrome.
    Experimental neurology, 2007, Volume: 204, Issue:2

    Topics: Amino Acids; Analysis of Variance; Anesthetics, Local; Animals; Back Pain; Disease Models, Animal; L

2007
Fluoroscopically guided caudal epidural steroid injections in degenerative lumbar spine stenosis.
    Pain physician, 2007, Volume: 10, Issue:4

    Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Back Pain; Cohort Studies; Female; Fluoroscopy; Follow

2007
Treatment of the chronic iliolumbar syndrome by infiltration of the iliolumbar ligament.
    The Western journal of medicine, 1982, Volume: 136, Issue:4

    Topics: Adult; Aged; Back Pain; Female; Glucose; Glucose Solution, Hypertonic; Humans; Ilium; Lidocaine; Lum

1982
Low back pain.
    Hospital practice (Office ed.), 1982, Volume: 17, Issue:11

    Topics: Adult; Back Pain; Chronic Disease; Electric Stimulation Therapy; Exercise Therapy; Female; Hot Tempe

1982
The role of physical agents in the treatment of spine pain.
    Clinical orthopaedics and related research, 1983, Issue:179

    Topics: Acupuncture Therapy; Administration, Topical; Back Pain; Humans; Hydrocortisone; Lidocaine; Short-Wa

1983
Anomalous ossicle of the articular process: arthrography and facet block.
    AJR. American journal of roentgenology, 1983, Volume: 141, Issue:6

    Topics: Adult; Anesthesia, Local; Arthrography; Back Pain; Humans; Lidocaine; Lumbar Vertebrae; Male

1983
Caudal epidural injections in treatment of lumbo-sciatic syndrome.
    The Journal of the Association of Physicians of India, 1983, Volume: 31, Issue:12

    Topics: Adrenal Cortex Hormones; Adult; Aged; Back Pain; Epidural Space; Female; Humans; Injections; Lidocai

1983
The facet joint and its role in spine pain. Management with facet joint injections.
    Spine, 1984, Volume: 9, Issue:7

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Back Pain; Female; Humans; Intervertebral Disc; L

1984
Lidocaine and the hyper-acute back.
    Colorado medicine, 1980, Volume: 77, Issue:1

    Topics: Back Pain; Humans; Lidocaine; Male; Middle Aged

1980
[Use of depolarization block in the treatment of backache].
    Chirurgia narzadow ruchu i ortopedia polska, 1980, Volume: 45, Issue:2

    Topics: Adult; Anesthetics, Local; Back Pain; Female; Humans; Injections, Intra-Articular; Intervertebral Di

1980
Lumbar facet joint injection in low back pain and sciatica: preliminary results.
    Radiology, 1980, Volume: 137, Issue:3

    Topics: Adult; Aged; Anesthetics, Local; Back Pain; Female; Fluoroscopy; Humans; Injections, Intra-Articular

1980
Lumbar facet joint injection in low back pain and sciatica: description of technique.
    Radiology, 1980, Volume: 137, Issue:3

    Topics: Anesthetics, Local; Back Pain; Fluoroscopy; Humans; Injections, Intra-Articular; Joint Diseases; Lid

1980
Lumbar dorsal ramus syndrome.
    The Medical journal of Australia, 1981, Oct-17, Volume: 2, Issue:8

    Topics: Back Pain; Humans; Lidocaine; Syndrome

1981
[Sacral epidural anesthesia in the treatment of lumbosacral backache].
    Schweizerische medizinische Wochenschrift, 1982, Feb-13, Volume: 112, Issue:7

    Topics: Adult; Aged; Anesthesia, Epidural; Back Pain; Female; Humans; Lidocaine; Male; Methylprednisolone; M

1982
Bilateral leg pain following lidocaine spinal anaesthesia.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1995, Volume: 42, Issue:3

    Topics: Achilles Tendon; Adult; Aged; Ambulatory Surgical Procedures; Anesthesia, Spinal; Back Pain; Cystosc

1995
Opisthotonus and hysteria.
    Anaesthesia, 1993, Volume: 48, Issue:5

    Topics: Adult; Analgesia, Epidural; Back Pain; Female; Humans; Hysteria; Lidocaine; Spasm

1993
Percutaneous facet denervation in chronic thoracic spinal pain.
    Acta neurochirurgica, 1993, Volume: 122, Issue:1-2

    Topics: Adult; Aged; Aged, 80 and over; Back Pain; Denervation; Electrocoagulation; Female; Follow-Up Studie

1993
Diagnostic obturator nerve block for inguinal and back pain: a recovered opinion.
    Pain, 1996, Volume: 67, Issue:2-3

    Topics: Back Pain; Bupivacaine; Electrodiagnosis; Female; Groin; Hip Joint; Humans; Injections, Intra-Articu

1996
The value of SPECT scans in identifying back pain likely to benefit from facet joint injection.
    British journal of rheumatology, 1996, Volume: 35, Issue:12

    Topics: Adolescent; Adult; Aged; Anesthetics, Local; Anti-Inflammatory Agents; Back Pain; Female; Humans; In

1996
Lidocaine toxicity: a technical knock-out below the waist?
    Acta anaesthesiologica Scandinavica, 1998, Volume: 42, Issue:4

    Topics: Anesthetics, Local; Back Pain; Humans; Lidocaine; Spinal Cord

1998
Transient radicular irritation (TRI) after spinal anaesthesia in day-care surgery.
    Acta anaesthesiologica Scandinavica, 1998, Volume: 42, Issue:4

    Topics: Adult; Ambulatory Surgical Procedures; Anesthesia, Spinal; Back Pain; Female; Humans; Lidocaine; Mal

1998
In my opinion: spinal lidocaine: a continuing enigma.
    Journal of clinical monitoring and computing, 1998, Volume: 14, Issue:2

    Topics: Anesthesia, Spinal; Anesthetics, Local; Back Pain; Humans; Lidocaine; Spinal Nerve Roots

1998
Procaine spinal anesthesia: a pilot study of the incidence of transient neurologic symptoms.
    Journal of clinical anesthesia, 1998, Volume: 10, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia Recovery Period; Anesthesia, Spinal; Anesthetics, Intrave

1998
Effect of experience with spinal anaesthesia on the development of post-dural puncture complications.
    Acta anaesthesiologica Scandinavica, 1999, Volume: 43, Issue:1

    Topics: Aged; Anesthesia, Spinal; Anesthesiology; Anesthetics, Local; Back Pain; Bupivacaine; Clinical Compe

1999
[The patient with back pain and the family physician. Problem solving with simple methods].
    MMW Fortschritte der Medizin, 1999, Jun-03, Volume: 141, Issue:22

    Topics: Acute Disease; Anesthetics, Local; Back Pain; Chiropractic; Humans; Lidocaine; Male; Manipulation, S

1999
Nonsurgical treatment of low back pain.
    Journal of neurosurgical nursing, 1977, Volume: 9, Issue:2

    Topics: Activities of Daily Living; Analgesics; Analgesics, Opioid; Anesthesia, Conduction; Back Pain; Brace

1977
Selective nerve root infiltration for the evaluation of sciatica.
    The Orthopedic clinics of North America, 1975, Volume: 6, Issue:1

    Topics: Back Pain; Humans; Injections; Lidocaine; Methods; Needles; Sciatica; Spinal Nerve Roots

1975
Symposium on the lumbar spine: Alternative approaches for the patient beyond the help of surgery.
    The Orthopedic clinics of North America, 1975, Volume: 6, Issue:1

    Topics: Back Pain; Follow-Up Studies; Humans; Hypertonic Solutions; Lidocaine; Steroids

1975
Epidural analgesia with left lateral tilt for Caesarean section.
    Anaesthesia, 1975, Volume: 30, Issue:3

    Topics: Adult; Anesthesia, Epidural; Apgar Score; Back Pain; Blood Pressure; Body Weight; Cesarean Section;

1975
Sedation of active acupuncture loci in the management of low back pain.
    The American journal of Chinese medicine, 1975, Volume: 3, Issue:3

    Topics: Acupuncture Therapy; Arachnoiditis; Back Pain; Humans; Injections; Lidocaine; Methylprednisolone; Ti

1975
Facet rhizotomy. Another armamentarium for treatment of low backache.
    North Carolina medical journal, 1976, Volume: 37, Issue:7

    Topics: Adult; Back Pain; Electrocoagulation; Electrosurgery; Female; Humans; Lidocaine; Male; Methods; Midd

1976
Follow-up status of patients treated with nerve blocks for low-back pain.
    Anesthesiology, 1977, Volume: 46, Issue:3

    Topics: Back Pain; Female; Follow-Up Studies; Humans; Injections, Spinal; Lidocaine; Male; Nerve Block; Suba

1977
[Treatment directives for patients with intervertebral-disk diseases of the lumbar spine].
    Medizinische Monatsschrift, 1977, Volume: 31, Issue:11

    Topics: Adult; Aged; Back Pain; Chronic Disease; Humans; Intervertebral Disc Displacement; Lidocaine; Lumbar

1977
Relieving pain with nerve blocks.
    Geriatrics, 1978, Volume: 33, Issue:4

    Topics: Acute Disease; Aged; Back Pain; Bursitis; Humans; Intervertebral Disc; Joint Diseases; Lidocaine; Mi

1978
A comparison of the types of epidural injection commonly used in the treatment of low back pain and sciatica.
    Rheumatology and rehabilitation, 1978, Volume: 17, Issue:3

    Topics: Back Pain; Dura Mater; Humans; Injections; Lidocaine; Sciatica; Sodium Chloride; Triamcinolone Aceto

1978
Back pain--what can we offer?
    British medical journal, 1979, Apr-21, Volume: 1, Issue:6170

    Topics: Back Pain; Drug Combinations; Humans; Lidocaine; Sacroiliac Joint; Triamcinolone Acetonide

1979
Iliolumbar syndrome as a common cause of low back pain: diagnosis and prognosis.
    Archives of physical medicine and rehabilitation, 1979, Volume: 60, Issue:9

    Topics: Adult; Back Pain; Diagnosis, Differential; Female; Glucocorticoids; Humans; Ilium; Lidocaine; Lumbos

1979
GP reports good results from back injection research.
    The Australasian nurses journal, 1979, Volume: 8, Issue:10

    Topics: Back Pain; Humans; Lidocaine; Physical Exertion; Triamcinolone

1979
Lumbar facet arthrography and injection in low back pain.
    Wisconsin medical journal, 1979, Volume: 78, Issue:12

    Topics: Back Pain; Bupivacaine; Humans; Injections; Lidocaine; Lumbar Vertebrae; Methylprednisolone; Radiogr

1979
Corticosteroid injections for chronic low back pain.
    The New England journal of medicine, 1992, Mar-19, Volume: 326, Issue:12

    Topics: Adrenal Cortex Hormones; Back Pain; Humans; Injections, Intra-Arterial; Lidocaine; Pain

1992
Back pain in volunteers after epidural anesthesia with chloroprocaine.
    Anesthesia and analgesia, 1991, Volume: 72, Issue:2

    Topics: Anesthesia, Epidural; Anesthetics, Local; Back Pain; Body Temperature Regulation; Humans; Lidocaine;

1991
[Therapeutic local anesthesia in acute back pain].
    Fortschritte der Medizin, 1991, Apr-30, Volume: 109, Issue:13

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anti-Inflammatory Agents, Non-Steroid

1991
Notalgia paraesthetica--report of three cases and their treatment.
    Clinical and experimental dermatology, 1991, Volume: 16, Issue:3

    Topics: Anesthetics, Local; Back Pain; Drug Combinations; Female; Humans; Hyperesthesia; Lidocaine; Lidocain

1991
Does chloroprocaine (Nesacaine MPF) for epidural anesthesia increase the incidence of backache?
    Anesthesiology, 1989, Volume: 71, Issue:3

    Topics: Adult; Anesthesia, Epidural; Anesthetics, Local; Back Pain; Drug Evaluation; Epinephrine; Humans; Li

1989
Distribution of pain provoked from lumbar facet joints and related structures during diagnostic spinal infiltration.
    Pain, 1989, Volume: 39, Issue:1

    Topics: Back Pain; Humans; Injections, Spinal; Lidocaine; Lumbar Vertebrae; Nerve Block; Pain; Pain Measurem

1989
Does topical anesthesia of the sphenopalatine ganglion with cocaine or lidocaine relieve low back pain?
    Anesthesia and analgesia, 1986, Volume: 65, Issue:6

    Topics: Administration, Topical; Adult; Aged; Back Pain; Cocaine; Double-Blind Method; Drug Evaluation; Fema

1986
[Diagnostic and therapeutic value of infiltrations under fluoroscopic control, in the vertebral facet syndrome].
    L'union medicale du Canada, 1986, Volume: 115, Issue:7

    Topics: Back Pain; Fluoroscopy; Humans; Injections, Intra-Articular; Lidocaine; Lumbar Vertebrae; Methylpred

1986
Facet joint degeneration as a cause of low back pain.
    Clinical orthopaedics and related research, 1986, Issue:213

    Topics: Adult; Aged; Back Pain; Female; Follow-Up Studies; Humans; Injections, Intra-Articular; Lidocaine; M

1986
Epidural steroid injection as a predictor of surgical outcome.
    Surgery, gynecology & obstetrics, 1987, Volume: 164, Issue:5

    Topics: Back Pain; Chymopapain; Humans; Injections, Spinal; Intervertebral Disc Chemolysis; Lidocaine; Methy

1987
Computed tomography and fluoroscopy guided anesthesia and steroid injection in facet syndrome.
    Spine, 1988, Volume: 13, Issue:6

    Topics: Anesthesia, Spinal; Back Pain; Betamethasone; Compartment Syndromes; Fluoroscopy; Humans; Injections

1988
Steroids and low-back pain.
    Hospital practice (Office ed.), 1985, Jan-15, Volume: 20, Issue:1

    Topics: Adult; Aged; Back Pain; Epidural Space; Evaluation Studies as Topic; Female; Humans; Injections; Lid

1985
Diagnostic epidural opioid blockade and chronic pain: preliminary report.
    Pain, 1985, Volume: 21, Issue:2

    Topics: Adult; Aged; Anesthesia, Epidural; Back Pain; Chronic Disease; Diagnosis, Differential; Female; Fent

1985
[The lignoicaine test in the diagnosis of pain in the lumbosacral spine].
    Chirurgia narzadow ruchu i ortopedia polska, 1985, Volume: 50, Issue:1

    Topics: Adult; Back Pain; Diagnosis, Differential; Female; Humans; Injections, Intra-Articular; Lidocaine; L

1985
Prevention of low back pain.
    Journal of occupational medicine. : official publication of the Industrial Medical Association, 1967, Volume: 9, Issue:11

    Topics: Accidents, Occupational; Back Pain; Exercise Therapy; Humans; Injections, Intramuscular; Lidocaine;

1967
Evaluation of low back pain by differential spinal block.
    Canadian Anaesthetists' Society journal, 1968, Volume: 15, Issue:5

    Topics: Anesthesia, Spinal; Back Pain; Diagnosis, Differential; Disability Evaluation; Humans; Lidocaine; Ps

1968
Therapeutic epidural block with a combination of a weak local anesthetic and steroids in management of complicated low back pain.
    The American surgeon, 1970, Volume: 36, Issue:5

    Topics: Adult; Autonomic Nerve Block; Back Pain; Dexamethasone; Fluprednisolone; Humans; Intervertebral Disc

1970
Amours M d',+AMOURS M: [Treatment of acute lumbalgia].
    Laval medical, 1969, Volume: 40, Issue:3

    Topics: Acute Disease; Back Pain; Drug Synergism; Female; Humans; Hydrocortisone; Injections; Intervertebral

1969
[Traumatic intervertebral disk disorders. A study of 31 new cases].
    Schweizer Archiv fur Neurologie, Neurochirurgie und Psychiatrie = Archives suisses de neurologie, neurochirurgie et de psychiatrie, 1971, Volume: 108, Issue:1

    Topics: Adult; Back Pain; Female; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Lidocaine;

1971
Chronic lumbosciatic syndrome treated by epidural injection and manipulation.
    The Practitioner, 1972, Volume: 209, Issue:249

    Topics: Adolescent; Adult; Aged; Anesthesia, Spinal; Back Pain; Female; Humans; Hydrocortisone; Lidocaine; M

1972
The spread of solutions injected into the epidural space. A study using epidurograms in patients with the lumbosciatic syndrome.
    British journal of anaesthesia, 1973, Volume: 45, Issue:4

    Topics: Adult; Age Factors; Aged; Anesthesia, Epidural; Back Pain; Body Height; Female; Humans; Hydrocortiso

1973
[Evaluation of the treatment of LIS (author's transl)].
    Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca, 1973, Volume: 40, Issue:4

    Topics: Adolescent; Adult; Back Pain; Baths; Child; Humans; Intervertebral Disc Displacement; Lidocaine; Lum

1973
Defining the origin of low-back pain: an injection technique.
    The Journal of the American Osteopathic Association, 1973, Volume: 73, Issue:3

    Topics: Back Pain; Humans; Intervertebral Disc Displacement; Lidocaine; Methods; Nerve Block; Sprains and St

1973
Treatment of chronic lumbosciatic pain.
    Proceedings of the Royal Society of Medicine, 1973, Volume: 66, Issue:6

    Topics: Anesthesia, Epidural; Back Pain; Edema; Follow-Up Studies; Humans; Hyaluronoglucosaminidase; Hydroco

1973
The gluteal syndrome of Steindler.
    The Nebraska medical journal, 1974, Volume: 59, Issue:9

    Topics: Back Pain; Cortisone; Ethyl Chloride; Female; Humans; Injections; Lidocaine

1974
Neurologic complications following spinal anesthesia with lidocaine: a prospective review of 10,440 cases.
    Anesthesiology, 1969, Volume: 30, Issue:3

    Topics: Adolescent; Adult; Anesthesia, Spinal; Back Pain; Female; Headache; Humans; Lidocaine; Male; Methods

1969