Page last updated: 2024-10-28

lidocaine and Autonomic Dysreflexia

lidocaine has been researched along with Autonomic Dysreflexia in 11 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Autonomic Dysreflexia: A syndrome associated with damage to the spinal cord above the mid thoracic level (see SPINAL CORD INJURIES) characterized by a marked increase in the sympathetic response to minor stimuli such as bladder or rectal distention. Manifestations include HYPERTENSION; TACHYCARDIA (or reflex bradycardia); FEVER; FLUSHING; and HYPERHIDROSIS. Extreme hypertension may be associated with a STROKE. (From Adams et al., Principles of Neurology, 6th ed, pp538 and 1232; J Spinal Cord Med 1997;20(3):355-60)

Research Excerpts

ExcerptRelevanceReference
"Lidocaine anal block significantly limits the autonomic dysreflexia response in susceptible patients undergoing anorectal procedures."9.11Lidocaine anal block limits autonomic dysreflexia during anorectal procedures in spinal cord injury: a randomized, double-blind, placebo-controlled trial. ( Cosman, BC; Vu, TT, 2005)
"Topical lidocaine did not significantly limit or prevent autonomic dysreflexia in susceptible patients."9.10Topical lidocaine does not limit autonomic dysreflexia during anorectal procedures in spinal cord injury: a prospective, double-blind study. ( Cosman, BC; Plowman, BK; Vu, TT, 2002)
"Bowel care is a potential trigger for autonomic dysreflexia (AD; paroxysmal hypertension elicited by sensory stimuli below the level of lesion)."6.94Clinical recommendations for use of lidocaine lubricant during bowel care after spinal cord injury prolong care routines and worsen autonomic dysreflexia: results from a randomised clinical trial. ( Claydon, VE; Inskip, JA; Lucci, VM; McGrath, MS; Sarveswaran, S; Willms, R, 2020)
"To systematically review the evidence on the use of local analgesics, specifically lidocaine or bupivacaine, to prevent autonomic dysreflexia (AD) during iatrogenic procedures or bowel and bladder care routines in individuals with spinal cord injury (SCI)."5.41Are local analgesics effective in reducing autonomic dysreflexia in individuals with spinal cord injury? A systematic review. ( Gray, K; Krassioukov, AV; Krogh, K; McCracken, L; Sachdeva, R; Sheehan, W, 2023)
"Lidocaine anal block significantly limits the autonomic dysreflexia response in susceptible patients undergoing anorectal procedures."5.11Lidocaine anal block limits autonomic dysreflexia during anorectal procedures in spinal cord injury: a randomized, double-blind, placebo-controlled trial. ( Cosman, BC; Vu, TT, 2005)
"Topical lidocaine did not significantly limit or prevent autonomic dysreflexia in susceptible patients."5.10Topical lidocaine does not limit autonomic dysreflexia during anorectal procedures in spinal cord injury: a prospective, double-blind study. ( Cosman, BC; Plowman, BK; Vu, TT, 2002)
"To obtain objective evidence for the time to onset of action for intravesical lidocaine utilizing exaggerated sympathetic blood-pressure responsiveness in patients with spinal cord injuries (SCI)."3.96Onset of the action of intravesical lidocaine after spinal cord injury. ( Linsenmeyer, TA; Solinsky, R; Tam, K, 2020)
"Bowel care is a potential trigger for autonomic dysreflexia (AD; paroxysmal hypertension elicited by sensory stimuli below the level of lesion)."2.94Clinical recommendations for use of lidocaine lubricant during bowel care after spinal cord injury prolong care routines and worsen autonomic dysreflexia: results from a randomised clinical trial. ( Claydon, VE; Inskip, JA; Lucci, VM; McGrath, MS; Sarveswaran, S; Willms, R, 2020)
"Chronic pain is common in patients with spinal cord injury (SCI)."1.33Pain management with interventional spine therapy in patients with spinal cord injury: a case series. ( Chiodo, A, 2005)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's0 (0.00)18.2507
2000's4 (36.36)29.6817
2010's0 (0.00)24.3611
2020's6 (54.55)2.80

Authors

AuthorsStudies
Gray, K2
Sheehan, W2
Wecht, J1
Linsenmeyer, TA2
Sachdeva, R3
Krassioukov, AV2
Lucci, VM2
McGrath, MS2
Inskip, JA2
Sarveswaran, S2
Willms, R2
Claydon, VE2
Kalimullina, T1
Pawar, K1
Krassioukov, A1
McCracken, L1
Krogh, K1
Solinsky, R1
Tam, K1
Furusawa, K1
Sugiyama, H1
Tokuhiro, A1
Takahashi, M1
Nakamura, T1
Tajima, F1
EADE, MN1
Cosman, BC2
Vu, TT2
Chiodo, A1
Plowman, BK1

Reviews

1 review available for lidocaine and Autonomic Dysreflexia

ArticleYear
Are local analgesics effective in reducing autonomic dysreflexia in individuals with spinal cord injury? A systematic review.
    Spinal cord, 2023, Volume: 61, Issue:1

    Topics: Adult; Analgesics; Autonomic Dysreflexia; Bupivacaine; Humans; Lidocaine; Spinal Cord Injuries

2023

Trials

4 trials available for lidocaine and Autonomic Dysreflexia

ArticleYear
Clinical recommendations for use of lidocaine lubricant during bowel care after spinal cord injury prolong care routines and worsen autonomic dysreflexia: results from a randomised clinical trial.
    Spinal cord, 2020, Volume: 58, Issue:4

    Topics: Adult; Autonomic Dysreflexia; Cross-Over Studies; Defecation; Double-Blind Method; Female; Humans; L

2020
Topical anesthesia blunts the pressor response induced by bowel manipulation in subjects with cervical spinal cord injury.
    Spinal cord, 2009, Volume: 47, Issue:2

    Topics: Adolescent; Adult; Analysis of Variance; Anesthesia, Local; Autonomic Dysreflexia; Blood Pressure; D

2009
Lidocaine anal block limits autonomic dysreflexia during anorectal procedures in spinal cord injury: a randomized, double-blind, placebo-controlled trial.
    Diseases of the colon and rectum, 2005, Volume: 48, Issue:8

    Topics: Anal Canal; Anesthetics, Local; Autonomic Dysreflexia; Blood Pressure; Double-Blind Method; Female;

2005
Topical lidocaine does not limit autonomic dysreflexia during anorectal procedures in spinal cord injury: a prospective, double-blind study.
    International journal of colorectal disease, 2002, Volume: 17, Issue:2

    Topics: Administration, Topical; Anesthetics, Local; Autonomic Dysreflexia; Blood Pressure; Double-Blind Met

2002

Other Studies

6 other studies available for lidocaine and Autonomic Dysreflexia

ArticleYear
Response to "Clinical recommendations for use of lidocaine lubricant during bowel care after spinal cord injury prolong care routines and worsen autonomic dysreflexia: results from a randomised clinical trial".
    Spinal cord, 2021, Volume: 59, Issue:12

    Topics: Autonomic Dysreflexia; Humans; Lidocaine; Lubricants; Spinal Cord Injuries

2021
Response to "Clinical recommendations for use of lidocaine lubricant during bowel care after spinal cord injury prolong care routines and worsen autonomic dysreflexia: results from a randomized clinical trial" - the authors reply.
    Spinal cord, 2021, Volume: 59, Issue:12

    Topics: Autonomic Dysreflexia; Humans; Lidocaine; Lubricants; Spinal Cord; Spinal Cord Injuries

2021
Rectal Application of Lidocaine Reduces the Severity of Autonomic Dysreflexia following Experimental Spinal Cord Injury.
    Journal of neurotrauma, 2022, Volume: 39, Issue:23-24

    Topics: Autonomic Dysreflexia; Blood Pressure; Humans; Lidocaine; Rectum; Spinal Cord; Spinal Cord Injuries

2022
Onset of the action of intravesical lidocaine after spinal cord injury.
    Neurourology and urodynamics, 2020, Volume: 39, Issue:1

    Topics: Adult; Autonomic Dysreflexia; Blood Pressure; Cohort Studies; Female; Humans; Lidocaine; Male; Middl

2020
PAROXYSMAL HYPERTENSION IN SPINAL CORD INJURIES (AUTONOMIC HYPERREFLEXIA).
    The New Zealand medical journal, 1964, Volume: 63

    Topics: Adolescent; Autonomic Dysreflexia; Autonomic Nervous System Diseases; Blushing; Bradycardia; Headach

1964
Pain management with interventional spine therapy in patients with spinal cord injury: a case series.
    The journal of spinal cord medicine, 2005, Volume: 28, Issue:4

    Topics: Adult; Anesthetics, Local; Anti-Inflammatory Agents; Autonomic Dysreflexia; Chronic Disease; Disease

2005