Page last updated: 2024-10-28

lidocaine and Atrioventricular Block

lidocaine has been researched along with Atrioventricular Block in 3 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Atrioventricular Block: Impaired impulse conduction from HEART ATRIA to HEART VENTRICLES. AV block can mean delayed or completely blocked impulse conduction.

Research Excerpts

ExcerptRelevanceReference
"This study investigated whether ranolazine reduces dofetilide-induced torsades de pointes (TdP) in a model of long QT syndrome with down-regulated K(+) currents due to hypertrophic remodeling in the dog with chronic atrioventricular block (cAVB)."7.76Late na(+) current inhibition by ranolazine reduces torsades de pointes in the chronic atrioventricular block dog model. ( Antoons, G; Beekman, JD; Belardinelli, L; Engelen, MA; Houtman, MJ; Oros, A; Stengl, M; Vos, MA, 2010)
"Pharmacokinetics of pilsicainide transdermal patch and its electropharmacological effects were simultaneously assessed using chronic atrioventricular block dogs."7.75Simultaneous assessment of pharmacokinetics of pilsicainide transdermal patch and its electropharmacological effects on atria of chronic atrioventricular block dogs. ( Iwasaki, H; Nagai, T; Nakamura, Y; Satoh, Y; Shinkai, N; Sugiyama, A; Takahara, A, 2009)
" However, we found an unusual in utero presentation of intermittent atrioventricular block and ventricular tachycardia (spontaneous or lidocaine-induced) in a fetus and his sibling with LQTS."7.74In utero onset of long QT syndrome with atrioventricular block and spontaneous or lidocaine-induced ventricular tachycardia: compound effects of hERG pore region mutation and SCN5A N-terminus variant. ( Chahine, M; Chang, CC; Chiu, SN; Christé, G; Ficker, E; Huang, H; Lin, MT; Thériault, O; Wu, MH, 2008)
"This study investigated whether ranolazine reduces dofetilide-induced torsades de pointes (TdP) in a model of long QT syndrome with down-regulated K(+) currents due to hypertrophic remodeling in the dog with chronic atrioventricular block (cAVB)."3.76Late na(+) current inhibition by ranolazine reduces torsades de pointes in the chronic atrioventricular block dog model. ( Antoons, G; Beekman, JD; Belardinelli, L; Engelen, MA; Houtman, MJ; Oros, A; Stengl, M; Vos, MA, 2010)
"Pharmacokinetics of pilsicainide transdermal patch and its electropharmacological effects were simultaneously assessed using chronic atrioventricular block dogs."3.75Simultaneous assessment of pharmacokinetics of pilsicainide transdermal patch and its electropharmacological effects on atria of chronic atrioventricular block dogs. ( Iwasaki, H; Nagai, T; Nakamura, Y; Satoh, Y; Shinkai, N; Sugiyama, A; Takahara, A, 2009)
" However, we found an unusual in utero presentation of intermittent atrioventricular block and ventricular tachycardia (spontaneous or lidocaine-induced) in a fetus and his sibling with LQTS."3.74In utero onset of long QT syndrome with atrioventricular block and spontaneous or lidocaine-induced ventricular tachycardia: compound effects of hERG pore region mutation and SCN5A N-terminus variant. ( Chahine, M; Chang, CC; Chiu, SN; Christé, G; Ficker, E; Huang, H; Lin, MT; Thériault, O; Wu, MH, 2008)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lin, MT1
Wu, MH1
Chang, CC1
Chiu, SN1
Thériault, O1
Huang, H1
Christé, G1
Ficker, E1
Chahine, M1
Iwasaki, H1
Takahara, A1
Nakamura, Y1
Satoh, Y1
Nagai, T1
Shinkai, N1
Sugiyama, A1
Antoons, G1
Oros, A1
Beekman, JD1
Engelen, MA1
Houtman, MJ1
Belardinelli, L1
Stengl, M1
Vos, MA1

Other Studies

3 other studies available for lidocaine and Atrioventricular Block

ArticleYear
In utero onset of long QT syndrome with atrioventricular block and spontaneous or lidocaine-induced ventricular tachycardia: compound effects of hERG pore region mutation and SCN5A N-terminus variant.
    Heart rhythm, 2008, Volume: 5, Issue:11

    Topics: Age of Onset; Anti-Arrhythmia Agents; Atrioventricular Block; ERG1 Potassium Channel; Ether-A-Go-Go

2008
Simultaneous assessment of pharmacokinetics of pilsicainide transdermal patch and its electropharmacological effects on atria of chronic atrioventricular block dogs.
    Journal of pharmacological sciences, 2009, Volume: 110, Issue:3

    Topics: Administration, Cutaneous; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrioventricular Bl

2009
Late na(+) current inhibition by ranolazine reduces torsades de pointes in the chronic atrioventricular block dog model.
    Journal of the American College of Cardiology, 2010, Feb-23, Volume: 55, Issue:8

    Topics: Acetanilides; Animals; Anti-Arrhythmia Agents; Atrioventricular Block; Dogs; Lidocaine; Models, Anim

2010