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lidocaine and Ataxia

lidocaine has been researched along with Ataxia in 17 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Ataxia: Impairment of the ability to perform smoothly coordinated voluntary movements. This condition may affect the limbs, trunk, eyes, pharynx, larynx, and other structures. Ataxia may result from impaired sensory or motor function. Sensory ataxia may result from posterior column injury or PERIPHERAL NERVE DISEASES. Motor ataxia may be associated with CEREBELLAR DISEASES; CEREBRAL CORTEX diseases; THALAMIC DISEASES; BASAL GANGLIA DISEASES; injury to the RED NUCLEUS; and other conditions.

Research Excerpts

ExcerptRelevanceReference
"Intrathecal administration of [D-Pro2,D-Trp7,9]-substance P to rats produced an irreversible flaccid paralysis of the hind limbs (paraplegia) which was irreversible with an ED50 of 2."3.67Species differences in the behavioral toxicity produced by intrathecal substance P antagonists: relationship to analgesia. ( Scott, R; Vaught, JL, 1987)
"The kinetics of tocainide, a new antiarrhythmic, and two of its metabolites, lactoxylidide (LX) and tocainide carbamoyl glucuronide (TG), were examined in patients given tocainide for 7 days following an acute myocardial infarction."3.66On the kinetics and dynamics of tocainide and its metabolites. ( Block, AJ; Ronfeld, RA; Wolshin, EM, 1982)
"All treatments induced mild or moderate ataxia."2.77Efficacy of concurrent epidural administration of neostigmine and lidocaine for perineal analgesia in geldings. ( DeRossi, R; Maciel, FB; Módolo, TJ; Pagliosa, RC, 2012)
"Development of any ataxia and/or sedation was recorded."2.71A comparison of the analgesic effects of caudal epidural methadone and lidocaine in the horse. ( Mosing, M; Olbrich, VH, 2003)
" The patient's central nervous system symptoms were mild and transient but remind us that to avoid adverse side effects, orally administered drugs with fairly high hepatic extraction ratio given to patients with chronic liver disease need to be given in reduced dosages."1.39Even 'safe' medications need to be administered with care. ( Dill, C; Gambetta, R; Howland, MA; Lutwak, N, 2013)
"Evaluations of analgesia, sedation, ataxia, heart rate, arterial pressure, respiratory rate, skin temperature and rectal temperature were obtained at 0 (basal), 5, 10, 15, 30, 45, 60, 75, 90 minutes after epidural injection, and then at 30-minute intervals until loss of analgesia occurred."1.36Segmental dorsolumbar epidural analgesia via the caudal approach using multiple port catheters with ketamine or lidocaine or in combination in cattle. ( Bertoni, RA; DeRossi, R; Frazílio, FO; Ruzzon, RH; Verde-Selva, AB, 2010)
"Evaluations of anaesthesia, ataxia, heart rate, arterial pressures, respiratory rate and rectal temperature were obtained at 0 (basal), 5, 10, 15, 30, 45, 60, 75, and 90 min after epidural injection and then at 30-min intervals until loss of anaesthesia."1.36Lignocaine versus bupivacaine for flank anaesthesia using multiport catheters via a caudal epidural approach in cattle. ( Bertoni, RA; DeRossi, R; Ruzzon, RH; Silva-Neto, AB; Verde-Selva, AB, 2010)
"Initial manifestations included hemiparesis, nystagmus, and ataxia."1.31Medial medullary injury during adenoidectomy. ( Dure, LS; Handler, SD; Kang, PB; Phuah, HK; Ryan, SG; Zimmerman, RA, 2001)
"Orphenadrine is an anticholinergic drug used mainly in the treatment of Parkinson's disease."1.30Orphenadrine poisoning in a child: clinical and analytical data. ( Maes, V; Mertens, K; Ramet, J; Van Herreweghe, I, 1999)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19905 (29.41)18.7374
1990's4 (23.53)18.2507
2000's3 (17.65)29.6817
2010's5 (29.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Catalano, A1
Desaphy, JF1
Lentini, G1
Carocci, A1
Di Mola, A1
Bruno, C1
Carbonara, R1
De Palma, A1
Budriesi, R1
Ghelardini, C1
Perrone, MG1
Colabufo, NA1
Conte Camerino, D1
Franchini, C1
DeRossi, R4
Bertoni, RA2
Ruzzon, RH2
Verde-Selva, AB2
Frazílio, FO1
Silva-Neto, AB1
Maciel, FB1
Módolo, TJ1
Pagliosa, RC1
Lutwak, N1
Howland, MA1
Gambetta, R1
Dill, C1
Junqueira, AL1
Beretta, MP1
Olbrich, VH1
Mosing, M1
Ronfeld, RA1
Wolshin, EM1
Block, AJ1
Shenkman, Z1
Findler, M1
Lossos, A1
Barak, S1
Katz, J1
Junge, RE1
Van Herreweghe, I1
Mertens, K1
Maes, V1
Ramet, J1
Kang, PB1
Phuah, HK1
Zimmerman, RA1
Handler, SD1
Dure, LS1
Ryan, SG1
de Jong, PT1
de Jong, JM1
Cohen, B1
Jongkees, LB1
Grubb, TL1
Riebold, TW1
Huber, MJ1
Vaught, JL1
Scott, R1
Breithardt, G1
Loogen, F1
Seipel, L1
Adamson, JE1
Cohen, BI1
Horton, CE1
Mladick, RA1
Gwyn, PP1

Reviews

1 review available for lidocaine and Ataxia

ArticleYear
[Long-term treatment of arrhythmias].
    Zeitschrift fur Kardiologie, 1974, Volume: 63, Issue:3

    Topics: Ajmaline; Arrhythmias, Cardiac; Ataxia; Electric Countershock; Gastrointestinal Diseases; Humans; Li

1974

Trials

2 trials available for lidocaine and Ataxia

ArticleYear
Efficacy of concurrent epidural administration of neostigmine and lidocaine for perineal analgesia in geldings.
    American journal of veterinary research, 2012, Volume: 73, Issue:9

    Topics: Analgesia, Epidural; Anesthetics, Local; Animals; Ataxia; Blood Pressure; Body Temperature; Cholines

2012
A comparison of the analgesic effects of caudal epidural methadone and lidocaine in the horse.
    Veterinary anaesthesia and analgesia, 2003, Volume: 30, Issue:3

    Topics: Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Animals; Ataxia; Cross-Over Studies; De

2003

Other Studies

14 other studies available for lidocaine and Ataxia

ArticleYear
Synthesis and toxicopharmacological evaluation of m-hydroxymexiletine, the first metabolite of mexiletine more potent than the parent compound on voltage-gated sodium channels.
    Journal of medicinal chemistry, 2012, Feb-09, Volume: 55, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Aorta; Ataxia; ATP Binding Cassette Transporter, Subfamily B, Membe

2012
Segmental dorsolumbar epidural analgesia via the caudal approach using multiple port catheters with ketamine or lidocaine or in combination in cattle.
    Veterinary anaesthesia and analgesia, 2010, Volume: 37, Issue:5

    Topics: Analgesia, Epidural; Analgesics; Animals; Ataxia; Blood Pressure; Body Temperature; Catheters; Cattl

2010
Lignocaine versus bupivacaine for flank anaesthesia using multiport catheters via a caudal epidural approach in cattle.
    Australian veterinary journal, 2010, Volume: 88, Issue:9

    Topics: Anesthesia, Epidural; Anesthetics, Local; Animals; Ataxia; Blood Pressure; Body Temperature; Bupivac

2010
Even 'safe' medications need to be administered with care.
    BMJ case reports, 2013, Jan-02, Volume: 2013

    Topics: Anesthetics, Local; Ataxia; Diplopia; Humans; Lidocaine; Liver Cirrhosis; Male; Middle Aged

2013
Analgesic and systemic effects of ketamine, xylazine, and lidocaine after subarachnoid administration in goats.
    American journal of veterinary research, 2003, Volume: 64, Issue:1

    Topics: Adrenergic alpha-Agonists; Analgesia; Anesthetics, Dissociative; Anesthetics, Local; Animals; Ataxia

2003
On the kinetics and dynamics of tocainide and its metabolites.
    Clinical pharmacology and therapeutics, 1982, Volume: 31, Issue:3

    Topics: Aged; Animals; Anti-Arrhythmia Agents; Ataxia; Female; Heart Conduction System; Humans; In Vitro Tec

1982
Permanent neurologic deficit after inferior alveolar nerve block: a case report.
    International journal of oral and maxillofacial surgery, 1996, Volume: 25, Issue:5

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Ataxia; Cranial Nerve Diseases; Facial Paralysis; Gai

1996
Epidural analgesia in addax (Addax nasomaculatus).
    Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 1998, Volume: 29, Issue:3

    Topics: Acepromazine; Adrenergic alpha-Agonists; Analgesia, Epidural; Anesthetics, Local; Animals; Antelopes

1998
Orphenadrine poisoning in a child: clinical and analytical data.
    Intensive care medicine, 1999, Volume: 25, Issue:10

    Topics: Akathisia, Drug-Induced; Anti-Arrhythmia Agents; Anticonvulsants; Antiparkinson Agents; Ataxia; Chil

1999
Medial medullary injury during adenoidectomy.
    The Journal of pediatrics, 2001, Volume: 138, Issue:5

    Topics: Adenoidectomy; Anesthetics, Local; Ataxia; Brain Stem; Child; Child, Preschool; Epinephrine; Humans;

2001
Ataxia and nystagmus induced by injection of local anesthetics in the Neck.
    Annals of neurology, 1977, Volume: 1, Issue:3

    Topics: Afferent Pathways; Animals; Ataxia; Cats; Haplorhini; Humans; Injections; Lidocaine; Macaca mulatta;

1977
Comparison of lidocaine, xylazine, and xylazine/lidocaine for caudal epidural analgesia in horses.
    Journal of the American Veterinary Medical Association, 1992, Oct-15, Volume: 201, Issue:8

    Topics: Analgesia, Epidural; Animals; Ataxia; Catheters, Indwelling; Drug Combinations; Female; Horses; Lido

1992
Species differences in the behavioral toxicity produced by intrathecal substance P antagonists: relationship to analgesia.
    Life sciences, 1987, Jan-12, Volume: 40, Issue:2

    Topics: Analgesia; Animals; Ataxia; Behavior, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Injecti

1987
Intravenous diazepam: a helpful adjunct in plastic surgery.
    Plastic and reconstructive surgery, 1971, Volume: 47, Issue:2

    Topics: Adolescent; Adult; Aged; Amnesia; Anesthesia, Local; Arrhythmias, Cardiac; Ataxia; Child; Diazepam;

1971