Page last updated: 2024-10-28

lidocaine and Asthma, Bronchial

lidocaine has been researched along with Asthma, Bronchial in 79 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Research Excerpts

ExcerptRelevanceReference
"Nebulized lidocaine may be a corticosteroid-sparing drug in human asthmatics, reducing airway resistance and peripheral blood eosinophilia."9.17Nebulized lidocaine blunts airway hyper-responsiveness in experimental feline asthma. ( Cohn, LA; Dodam, JR; Guntur, VP; Lee-Fowler, TM; Nafe, LA; Reinero, CR, 2013)
"We conducted two double-blind, placebo-controlled, clinical studies assessing lidocaine solution for inhalation (LSI; 40 mg twice daily; eFlow(®) nebulizer) to treat asthma."9.14Inhaled lidocaine for the treatment of asthma: lack of efficacy in two double-blind, randomized, placebo-controlled clinical studies. ( Abuan, T; Montgomery, AB; Yeager, M, 2010)
"Although prophylactic IV administration of lidocaine attenuates the response to a variety of inhalation challenges, its effect on airway resistance after endotracheal intubation in patients with asthma is unclear."9.12Intravenous lidocaine after tracheal intubation mitigates bronchoconstriction in patients with asthma. ( Adamzik, M; Farahani, R; Groeben, H; Lehmann, N; Peters, J, 2007)
"We tested the safety and efficacy of nebulized lidocaine in a randomized, placebo-controlled study in patients with mild-to-moderate asthma."9.11Treatment of asthma with nebulized lidocaine: a randomized, placebo-controlled study. ( Blomgren, J; Butterfield, JH; Dunnette, SL; Frigas, E; Gleich, GJ; Hunt, LW; Kita, H; Offord, KP, 2004)
"Inhaled albuterol blunted airway response to tracheal intubation in asthmatic patients, whereas intravenous lidocaine did not."9.09Inhaled albuterol, but not intravenous lidocaine, protects against intubation-induced bronchoconstriction in asthma. ( Boughton, R; Darvish, A; Israel, E; Loring, SH; Maslow, AD; Mehrez, M; Regan, MM, 2000)
" placebo in 15 mild asthmatic patients, selected by their response to a histamine challenge (decrease in FEV1 > 20% to less than 18 mg mL-1 of histamine [PC20])."9.09Lidocaine inhalation for local anaesthesia and attenuation of bronchial hyper-reactivity with least airway irritation. Effect of three different dose regimens. ( Beste, M; Groeben, H; Grosswendt, T; Peters, J; Silvanus, M, 2000)
" The aim was to study cough and other capsaicin-induced symptoms and to test the effect of a drug (lidocaine) that inhibits nerve transmission in sensory nerves."9.09Cough provocation with capsaicin is an objective way to test sensory hyperreactivity in patients with asthma-like symptoms. ( Millqvist, E, 2000)
"Inhaled topical lidocaine, used to produce anesthesia of the respiratory tract prior to bronchoscopy, may cause bronchoconstriction in asthmatic patients."9.06Lidocaine-induced bronchoconstriction in asthmatic patients. Relation to histamine airway responsiveness and effect of preservative. ( McAlpine, LG; Thomson, NC, 1989)
"The effect of 4% lidocaine inhalation was studied in a single-blind fashion in 18 patients with chronic stable asthma."9.06Effect of 4% lidocaine inhalation in bronchial asthma. ( Pande, JN; Prakash, GS; Sharma, SK, 1990)
" Seven studies (6 descriptive studies and 1 clinical trial) evaluating the use of nebulized lidocaine in intractable cough reported efficacy in doses ranging from 10 mg to 400 mg."8.89Evidence for therapeutic uses of nebulized lidocaine in the treatment of intractable cough and asthma. ( Mbathi, JW; Slaton, RM; Thomas, RH, 2013)
"Evidence suggests that nebulized lidocaine is beneficial in asthma therapy, but to what extent and the mechanisms underlying this effect remain poorly understood."7.78Nebulized lidocaine prevents airway inflammation, peribronchial fibrosis, and mucus production in a murine model of asthma. ( Anjos-Valotta, EA; Arantes, AC; Cordeiro, RS; Cotias, AC; Couto, GC; Ferreira, TP; Jurgilas, PB; Martins, MA; Olsen, PC; Pão, CR; Pires, AL; Serra, MF; Silva, PM, 2012)
"Small, medium, and large airways (2-5, 5-8, >8 mm diameter) were analyzed by computed tomography in 15 asthmatic volunteers under baseline conditions and during infusion of lidocaine."7.74The effects of systemic lidocaine on airway tone and pulmonary function in asthmatic subjects. ( Brown, RH; Chang, HY; Togias, A, 2007)
"Fentanyl-induced cough may be suppressed by aging, cigarette smoking, prior epidural injection of lidocaine, or a priming dose of vecuronium."7.73Identification of independent risk factors for fentanyl-induced cough. ( Dohi, S; Kasuya, Y; Murakami, T; Okumura, Y; Oshima, T, 2006)
"We report a case of a pregnant woman with severe asthma that was not controlled with ordinary medications but was effectively treated by inhalational lidocaine treatment."7.73[A pregnant woman with severe asthma effectively treated by inhalational lidocaine therapy]. ( Hagiwara, K; Kanazawa, M; Nagata, M; Saito, K; Sato, N; Shimono, N, 2006)
"The purpose of this study was to observe the effectiveness of lidocaine in suppressing cough which is a logical extension of its established use in bronchoscopy."7.71Lidocaine inhalation for cough suppression. ( Udezue, E, 2001)
"We sought to investigate the effect of lidocaine on T cells from patients with allergic asthma."7.71Inhibitory effect of lidocaine on T cells from patients with allergic asthma. ( Adachi, M; Matsuo, H; Minoguchi, K; Oda, N; Okada, S; Tanaka, A; Tasaki, T; Yokoe, T, 2002)
"To determine how often serum lidocaine concentrations (SLC) fall into the potentially toxic range (> 5 mg/L) in asthmatics undergoing research bronchoscopy, and to determine whether subject or procedure characteristics are associated with higher SLC."7.70Serum lidocaine concentrations in asthmatics undergoing research bronchoscopy. ( Kraft, M; Langmack, EL; Martin, RJ; Pak, J, 2000)
"After further study, lidocaine may prove to be the first non-toxic, steroid alternative to patients with severe steroid-dependent asthma."7.70Nebulized lidocaine in the treatment of severe asthma in children: a pilot study. ( Decco, ML; Hunt, LW; Neeno, TA; O'Connell, EJ; Sachs, MI; Yunginger, JW, 1999)
"To determine whether nebulized lidocaine is a useful therapy in patients with severe glucocorticoid-dependent asthma."7.69Effect of nebulized lidocaine on severe glucocorticoid-dependent asthma. ( Gleich, GJ; Hunt, LW; Swedlund, HA, 1996)
"We measured the effect of inhaled lidocaine on pulmonary function in 8 asthmatic subjects."7.66Effects of inhaled lidocaine on airway function in asthmatic subjects. ( Fish, JE; Peterman, VI, 1979)
"An aerosol of 4% lidocaine was delivered during the last third of inspiration to patients with bronchial asthma while they were quietly breathing."7.66Effect of lidocaine on the ventilatory and airway responses to exercise in asthmatics. ( Enright, PL; McNally, JF; Souhrada, JF, 1980)
"Pretreatment with lidocaine, the beta-receptor agonist, terbutaline, or the adenosine non-blocking xanthine, enprofylline, inhibited the capsaicine induced inflammatory response."5.27Anti-asthma drugs and capsaicine-induced microvascular effects in lower airways. ( Erjefält, I; Persson, CG, 1985)
"Nebulized lidocaine may be a corticosteroid-sparing drug in human asthmatics, reducing airway resistance and peripheral blood eosinophilia."5.17Nebulized lidocaine blunts airway hyper-responsiveness in experimental feline asthma. ( Cohn, LA; Dodam, JR; Guntur, VP; Lee-Fowler, TM; Nafe, LA; Reinero, CR, 2013)
"We conducted two double-blind, placebo-controlled, clinical studies assessing lidocaine solution for inhalation (LSI; 40 mg twice daily; eFlow(®) nebulizer) to treat asthma."5.14Inhaled lidocaine for the treatment of asthma: lack of efficacy in two double-blind, randomized, placebo-controlled clinical studies. ( Abuan, T; Montgomery, AB; Yeager, M, 2010)
"Although prophylactic IV administration of lidocaine attenuates the response to a variety of inhalation challenges, its effect on airway resistance after endotracheal intubation in patients with asthma is unclear."5.12Intravenous lidocaine after tracheal intubation mitigates bronchoconstriction in patients with asthma. ( Adamzik, M; Farahani, R; Groeben, H; Lehmann, N; Peters, J, 2007)
"We tested the safety and efficacy of nebulized lidocaine in a randomized, placebo-controlled study in patients with mild-to-moderate asthma."5.11Treatment of asthma with nebulized lidocaine: a randomized, placebo-controlled study. ( Blomgren, J; Butterfield, JH; Dunnette, SL; Frigas, E; Gleich, GJ; Hunt, LW; Kita, H; Offord, KP, 2004)
"In asthmatics, awake fiberoptic intubation evokes a more than 50% decrease in FEV1 following dyclonine inhalation."5.10Both local anesthetics and salbutamol pretreatment affect reflex bronchoconstriction in volunteers with asthma undergoing awake fiberoptic intubation. ( Groeben, H; Pavlakovic, G; Peters, J; Schlicht, M; Stieglitz, S, 2002)
" placebo in 15 mild asthmatic patients, selected by their response to a histamine challenge (decrease in FEV1 > 20% to less than 18 mg mL-1 of histamine [PC20])."5.09Lidocaine inhalation for local anaesthesia and attenuation of bronchial hyper-reactivity with least airway irritation. Effect of three different dose regimens. ( Beste, M; Groeben, H; Grosswendt, T; Peters, J; Silvanus, M, 2000)
"Inhaled albuterol blunted airway response to tracheal intubation in asthmatic patients, whereas intravenous lidocaine did not."5.09Inhaled albuterol, but not intravenous lidocaine, protects against intubation-induced bronchoconstriction in asthma. ( Boughton, R; Darvish, A; Israel, E; Loring, SH; Maslow, AD; Mehrez, M; Regan, MM, 2000)
" The aim was to study cough and other capsaicin-induced symptoms and to test the effect of a drug (lidocaine) that inhibits nerve transmission in sensory nerves."5.09Cough provocation with capsaicin is an objective way to test sensory hyperreactivity in patients with asthma-like symptoms. ( Millqvist, E, 2000)
"The effect of 4% lidocaine inhalation was studied in a single-blind fashion in 18 patients with chronic stable asthma."5.06Effect of 4% lidocaine inhalation in bronchial asthma. ( Pande, JN; Prakash, GS; Sharma, SK, 1990)
"Inhaled topical lidocaine, used to produce anesthesia of the respiratory tract prior to bronchoscopy, may cause bronchoconstriction in asthmatic patients."5.06Lidocaine-induced bronchoconstriction in asthmatic patients. Relation to histamine airway responsiveness and effect of preservative. ( McAlpine, LG; Thomson, NC, 1989)
" Seven studies (6 descriptive studies and 1 clinical trial) evaluating the use of nebulized lidocaine in intractable cough reported efficacy in doses ranging from 10 mg to 400 mg."4.89Evidence for therapeutic uses of nebulized lidocaine in the treatment of intractable cough and asthma. ( Mbathi, JW; Slaton, RM; Thomas, RH, 2013)
"Evidence suggests that nebulized lidocaine is beneficial in asthma therapy, but to what extent and the mechanisms underlying this effect remain poorly understood."3.78Nebulized lidocaine prevents airway inflammation, peribronchial fibrosis, and mucus production in a murine model of asthma. ( Anjos-Valotta, EA; Arantes, AC; Cordeiro, RS; Cotias, AC; Couto, GC; Ferreira, TP; Jurgilas, PB; Martins, MA; Olsen, PC; Pão, CR; Pires, AL; Serra, MF; Silva, PM, 2012)
"Inhalation of JMF2-1, an analog of lidocaine with reduced anesthetic activity, prevents airway contraction and lung inflammation in experimental asthma models."3.78Two for one: cyclic AMP mediates the anti-inflammatory and anti-spasmodic properties of the non-anesthetic lidocaine analog JMF2-1. ( Coelho, LP; Cordeiro, RS; da Costa, JC; Martins, MA; Olsen, PC; Silva, PM, 2012)
"Small, medium, and large airways (2-5, 5-8, >8 mm diameter) were analyzed by computed tomography in 15 asthmatic volunteers under baseline conditions and during infusion of lidocaine."3.74The effects of systemic lidocaine on airway tone and pulmonary function in asthmatic subjects. ( Brown, RH; Chang, HY; Togias, A, 2007)
"We report a case of a pregnant woman with severe asthma that was not controlled with ordinary medications but was effectively treated by inhalational lidocaine treatment."3.73[A pregnant woman with severe asthma effectively treated by inhalational lidocaine therapy]. ( Hagiwara, K; Kanazawa, M; Nagata, M; Saito, K; Sato, N; Shimono, N, 2006)
"Fentanyl-induced cough may be suppressed by aging, cigarette smoking, prior epidural injection of lidocaine, or a priming dose of vecuronium."3.73Identification of independent risk factors for fentanyl-induced cough. ( Dohi, S; Kasuya, Y; Murakami, T; Okumura, Y; Oshima, T, 2006)
"The purpose of this study was to observe the effectiveness of lidocaine in suppressing cough which is a logical extension of its established use in bronchoscopy."3.71Lidocaine inhalation for cough suppression. ( Udezue, E, 2001)
"We sought to investigate the effect of lidocaine on T cells from patients with allergic asthma."3.71Inhibitory effect of lidocaine on T cells from patients with allergic asthma. ( Adachi, M; Matsuo, H; Minoguchi, K; Oda, N; Okada, S; Tanaka, A; Tasaki, T; Yokoe, T, 2002)
"To determine how often serum lidocaine concentrations (SLC) fall into the potentially toxic range (> 5 mg/L) in asthmatics undergoing research bronchoscopy, and to determine whether subject or procedure characteristics are associated with higher SLC."3.70Serum lidocaine concentrations in asthmatics undergoing research bronchoscopy. ( Kraft, M; Langmack, EL; Martin, RJ; Pak, J, 2000)
"After further study, lidocaine may prove to be the first non-toxic, steroid alternative to patients with severe steroid-dependent asthma."3.70Nebulized lidocaine in the treatment of severe asthma in children: a pilot study. ( Decco, ML; Hunt, LW; Neeno, TA; O'Connell, EJ; Sachs, MI; Yunginger, JW, 1999)
"To determine whether nebulized lidocaine is a useful therapy in patients with severe glucocorticoid-dependent asthma."3.69Effect of nebulized lidocaine on severe glucocorticoid-dependent asthma. ( Gleich, GJ; Hunt, LW; Swedlund, HA, 1996)
" Since bronchoscopy was performed after pretreatment with atropine and under topical anesthesia with lignocaine, histamine chloride tests were also performed in 6 asthmatics before and after atropine, and in 6 asthmatics before and after local anesthesia with lignocaine."3.67Flexible fiberoptic bronchoscopy does not alter airway responsiveness. ( Lundgren, R; Söderberg, M, 1989)
"An aerosol of 4% lidocaine was delivered during the last third of inspiration to patients with bronchial asthma while they were quietly breathing."3.66Effect of lidocaine on the ventilatory and airway responses to exercise in asthmatics. ( Enright, PL; McNally, JF; Souhrada, JF, 1980)
"We measured the effect of inhaled lidocaine on pulmonary function in 8 asthmatic subjects."3.66Effects of inhaled lidocaine on airway function in asthmatic subjects. ( Fish, JE; Peterman, VI, 1979)
"To investigate the possibility that stimulation of neural receptors in the posterior pharynx plays a role in the pathogenesis of exercise-induced asthma, we had 10 asthmatic subjects simulate the hyperpnea of exercise by performing eucapnic hypervenilation in the presence and absence of oropharyngeal anesthesia induced by lidocaine."3.66A reassessment of the effects of oropharyngeal anesthesia in exercise-induced asthma. ( Fanta, CH; Ingram, RH; McFadden, ER, 1980)
" PD20 was interpolated from the dose-response curve, relating the dose of cold air on a non-cumulative logarithmic scale on the abscissa and the percentage change in FEV1 on the ordinate."2.66Inhaled lignocaine does not alter bronchial hyperresponsiveness to hyperventilation of dry cold air in asthmatic subjects. ( Caire, N; Cartier, A; Ghezzo, H; L'Archevêque, J; Malo, JL, 1989)
"Episodic airway obstruction and reversible bronchial hyperresponsiveness to non-specific irritants are the major symptoms of asthma."1.33Bronchial epilepsy or broncho-pulmonary hyper-excitability as a model of asthma pathogenesis. ( Graeme Shaw, D; Hoang, BX; Hoang, C; Levine, SA; Pham, P, 2006)
"Lidocaine aerosols have been ineffective at preventing airway constriction provoked by non-reflex stimuli."1.27Comparison of local anesthetics as bronchodilator aerosols. ( Downes, H; Hirshman, CA; Leon, DA, 1983)
" We performed the distilled water dose-response curves after no treatment and after treatment with cromolyn aerosol, lidocaine aerosol, or atropine aerosol in doses of 0."1.27Mechanism of cough and bronchoconstriction induced by distilled water aerosol. ( Bethel, RA; Boushey, HA; Rizk, NW; Sheppard, D, 1983)
"Pretreatment with lidocaine, the beta-receptor agonist, terbutaline, or the adenosine non-blocking xanthine, enprofylline, inhibited the capsaicine induced inflammatory response."1.27Anti-asthma drugs and capsaicine-induced microvascular effects in lower airways. ( Erjefält, I; Persson, CG, 1985)

Research

Studies (79)

TimeframeStudies, this research(%)All Research%
pre-199034 (43.04)18.7374
1990's17 (21.52)18.2507
2000's19 (24.05)29.6817
2010's8 (10.13)24.3611
2020's1 (1.27)2.80

Authors

AuthorsStudies
Mahalingam-Dhingra, A1
Mazan, MR1
Bedenice, D1
Ceresia, M1
Minuto, J1
Deveney, EF1
Slaton, RM1
Thomas, RH1
Mbathi, JW1
Harrington, M1
King, G1
Byrne, A1
Fleming, P1
Burches, BR1
Warner, DO1
Abuan, T1
Yeager, M1
Montgomery, AB1
Olsen, PC2
Coelho, LP1
da Costa, JC1
Cordeiro, RS3
Silva, PM2
Martins, MA3
Serra, MF2
Anjos-Valotta, EA1
Couto, GC1
Jurgilas, PB1
Cotias, AC1
Pão, CR1
Ferreira, TP1
Arantes, AC1
Pires, AL1
Ripley, A1
Castro, J1
Gadsden, J1
Nafe, LA1
Guntur, VP1
Dodam, JR1
Lee-Fowler, TM1
Cohn, LA1
Reinero, CR1
Groeben, H5
Schlicht, M1
Stieglitz, S1
Pavlakovic, G1
Peters, J3
ZICHA, L1
SCHEIFFARTH, F1
SCHEPP, F1
BERGNER, D1
METZLER, K1
RAJKA, G1
SKOG, E1
DESCOMPS, H1
GAIN, EA1
TULLOCH, A1
CASHELL, GT1
THOMAS, KB1
Govindarajan, R1
Chaudhry, R1
Babalola, O1
Nguyen, N1
Michael, R1
Sultan, S1
Hunt, LW3
Frigas, E1
Butterfield, JH1
Kita, H2
Blomgren, J1
Dunnette, SL1
Offord, KP1
Gleich, GJ3
Siqueira, RA1
Costa, JC1
e Silva, PM1
Hoang, BX1
Levine, SA1
Graeme Shaw, D1
Pham, P1
Hoang, C1
Oshima, T1
Kasuya, Y1
Okumura, Y1
Murakami, T1
Dohi, S1
Saito, K1
Sato, N1
Shimono, N1
Hagiwara, K1
Kanazawa, M1
Nagata, M1
Adamzik, M1
Farahani, R1
Lehmann, N1
Chang, HY1
Togias, A1
Brown, RH2
Gottlieb, SJ1
Falliers, CJ1
Tullett, WM1
Patel, KR1
Berkin, KE1
Kerr, JW1
Stirt, JA1
Sullivan, SF1
Hida, W1
Arai, M1
Shindoh, C1
Liu, YN1
Sasaki, H1
Takishima, T1
Sheppard, D1
Rizk, NW1
Boushey, HA1
Bethel, RA1
Krasnowska, M1
Liebhart, E1
Małolepszy, J1
Downes, H1
Hirshman, CA1
Leon, DA1
Griffin, MP1
McFadden, ER2
Ingram, RH2
Pardee, S1
Fanta, CH1
Runovich, AA1
Baturin, SM1
Varnakov, AA1
Enright, PL1
McNally, JF1
Souhrada, JF1
Zemenick, RB3
Rabold, M1
Tintinalli, J1
Kuwahara, B1
Goresky, GV1
Walls, RM1
Ohnishi, T1
Mayeno, AN1
Okada, S2
Sur, S1
Broide, DH1
Swedlund, HA1
Foster, WM1
Floreani, AA1
Rennard, SI1
Decco, ML1
Neeno, TA1
O'Connell, EJ1
Yunginger, JW1
Sachs, MI1
Harrison, TW1
Tattersfield, AE1
Deykin, A1
Israel, E2
Patel, J1
Langmack, EL1
Martin, RJ1
Pak, J1
Kraft, M1
Millqvist, E1
Grosswendt, T1
Silvanus, M1
Beste, M1
Rosario, NA1
Riedi, CA1
Farias, L1
Maslow, AD1
Regan, MM1
Darvish, A1
Mehrez, M1
Boughton, R1
Loring, SH1
Udezue, E1
Cetinkaya, F1
Tanaka, A1
Minoguchi, K1
Oda, N1
Yokoe, T1
Matsuo, H1
Tasaki, T1
Adachi, M1
Weiss, EB1
Patwardhan, AV1
Fish, JE1
Peterman, VI1
Miller, MM1
Patterson, R1
Harris, KE1
Strashnov, VI1
Tuleutaev, TB1
Nakai, S1
Iikura, Y1
Akimoto, K1
Shiraki, K1
Erjefält, I2
Persson, CG2
Prakash, GS1
Sharma, SK1
Pande, JN1
Söderberg, M1
Lundgren, R1
Caire, N1
Cartier, A1
Ghezzo, H1
L'Archevêque, J1
Malo, JL1
McAlpine, LG1
Thomson, NC1
Chen, WY1
Chai, H1
Fink, A1
Bibi, H1
Eliraz, A1
Tabachnik, E1
Bentwich, Z1
Hopfer, F1
Shields, PW1
Rodriguez-Martinez, F1
Mascia, AV1
Mellins, RB1
Helm, WH1
Barran, KM1
Mukerjee, SC1
Gruszecka, M1
Kralisz, W1
Bennett, DJ1
Torda, TA1
Horton, DA1
Wright, JS1
Eisele, JH1
Jain, SK1
Borisko, AS1
Chernobrovyĭ, NP1

Reviews

6 reviews available for lidocaine and Asthma, Bronchial

ArticleYear
Evidence for therapeutic uses of nebulized lidocaine in the treatment of intractable cough and asthma.
    The Annals of pharmacotherapy, 2013, Volume: 47, Issue:4

    Topics: Administration, Inhalation; Anti-Arrhythmia Agents; Asthma; Clinical Trials as Topic; Cough; Humans;

2013
Effects of high thoracic epidural anesthesia and local anesthetics on bronchial hyperreactivity.
    Journal of clinical monitoring and computing, 2000, Volume: 16, Issue:5-6

    Topics: Anesthesia, Epidural; Anesthetics, Local; Asthma; Bronchial Hyperreactivity; Humans; Lidocaine; Post

2000
Local anaesthetic medication for the treatment of asthma.
    Memorias do Instituto Oswaldo Cruz, 2005, Volume: 100 Suppl 1

    Topics: Anesthetics, Local; Anti-Asthmatic Agents; Asthma; Humans; Lidocaine

2005
Aminophylline.
    Anesthesia and analgesia, 1981, Volume: 60, Issue:8

    Topics: Adult; Aminophylline; Anesthesia; Animals; Anticonvulsants; Arrhythmias, Cardiac; Asthma; Biotransfo

1981
Experimental treatments for asthma.
    Current opinion in pulmonary medicine, 1997, Volume: 3, Issue:1

    Topics: Administration, Inhalation; Anti-Inflammatory Agents; Antirheumatic Agents; Asthma; Auranofin; Brady

1997
Newer therapeutic agents for asthma.
    Disease-a-month : DM, 1999, Volume: 45, Issue:4

    Topics: Adrenergic beta-Agonists; Albuterol; Androstadienes; Anti-Asthmatic Agents; Asthma; Bronchodilator A

1999

Trials

16 trials available for lidocaine and Asthma, Bronchial

ArticleYear
A CONSORT-guided, randomized, double-blind, controlled pilot clinical trial of inhaled lidocaine for the treatment of equine asthma.
    Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 2022, Volume: 86, Issue:2

    Topics: Administration, Inhalation; Animals; Asthma; Bronchoalveolar Lavage; Budesonide; Double-Blind Method

2022
Inhaled lidocaine for the treatment of asthma: lack of efficacy in two double-blind, randomized, placebo-controlled clinical studies.
    Journal of aerosol medicine and pulmonary drug delivery, 2010, Volume: 23, Issue:6

    Topics: Administration, Inhalation; Adrenal Cortex Hormones; Adult; Anti-Asthmatic Agents; Asthma; Double-Bl

2010
Nebulized lidocaine blunts airway hyper-responsiveness in experimental feline asthma.
    Journal of feline medicine and surgery, 2013, Volume: 15, Issue:8

    Topics: Airway Resistance; Allergens; Anesthetics, Local; Animals; Asthma; Bronchoconstrictor Agents; Cat Di

2013
Both local anesthetics and salbutamol pretreatment affect reflex bronchoconstriction in volunteers with asthma undergoing awake fiberoptic intubation.
    Anesthesiology, 2002, Volume: 97, Issue:6

    Topics: Adult; Airway Resistance; Albuterol; Anesthetics, Local; Asthma; Bronchial Provocation Tests; Bronch

2002
Treatment of asthma with nebulized lidocaine: a randomized, placebo-controlled study.
    The Journal of allergy and clinical immunology, 2004, Volume: 113, Issue:5

    Topics: Administration, Inhalation; Adolescent; Adult; Anti-Asthmatic Agents; Asthma; Eosinophils; Female; F

2004
Intravenous lidocaine after tracheal intubation mitigates bronchoconstriction in patients with asthma.
    Anesthesia and analgesia, 2007, Volume: 104, Issue:1

    Topics: Adult; Aged; Airway Resistance; Anesthetics, Local; Asthma; Blood Pressure; Bronchoconstriction; Hea

2007
Effect of lignocaine, sodium cromoglycate, and ipratropium bromide in exercise-induced asthma.
    Thorax, 1982, Volume: 37, Issue:10

    Topics: Adolescent; Adult; Aerosols; Asthma; Asthma, Exercise-Induced; Atropine Derivatives; Clinical Trials

1982
Intravenous lidocaine and oral mexiletine block reflex bronchoconstriction in asthmatic subjects.
    American journal of respiratory and critical care medicine, 1996, Volume: 154, Issue:4 Pt 1

    Topics: Adult; Anesthetics, Local; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Double-Blind Me

1996
Effect of single doses of inhaled lignocaine on FEV1 and bronchial reactivity in asthma.
    Respiratory medicine, 1998, Volume: 92, Issue:12

    Topics: Administration, Inhalation; Adult; Albuterol; Anesthetics, Local; Asthma; Bronchial Hyperreactivity;

1998
Cough provocation with capsaicin is an objective way to test sensory hyperreactivity in patients with asthma-like symptoms.
    Allergy, 2000, Volume: 55, Issue:6

    Topics: Administration, Inhalation; Adult; Anesthetics, Local; Asthma; Capsaicin; Cough; Dose-Response Relat

2000
Lidocaine inhalation for local anaesthesia and attenuation of bronchial hyper-reactivity with least airway irritation. Effect of three different dose regimens.
    European journal of anaesthesiology, 2000, Volume: 17, Issue:11

    Topics: Adult; Airway Resistance; Anesthetics, Inhalation; Anesthetics, Local; Asthma; Bronchi; Bronchial Hy

2000
Inhaled albuterol, but not intravenous lidocaine, protects against intubation-induced bronchoconstriction in asthma.
    Anesthesiology, 2000, Volume: 93, Issue:5

    Topics: Administration, Inhalation; Adult; Albuterol; Anesthesia, Inhalation; Anesthetics, Inhalation; Anest

2000
The response to lidocaine in bronchial asthma.
    Chest, 1977, Volume: 72, Issue:4

    Topics: Adult; Aerosols; Airway Resistance; Asthma; Clinical Trials as Topic; Dose-Response Relationship, Dr

1977
Effect of 4% lidocaine inhalation in bronchial asthma.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 1990, Volume: 27, Issue:2

    Topics: Administration, Inhalation; Adolescent; Adult; Asthma; Carbon Dioxide; Female; Humans; Lidocaine; Lu

1990
Inhaled lignocaine does not alter bronchial hyperresponsiveness to hyperventilation of dry cold air in asthmatic subjects.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1989, Volume: 19, Issue:1

    Topics: Administration, Inhalation; Adolescent; Adult; Aged; Asthma; Bronchi; Bronchial Provocation Tests; C

1989
Lidocaine-induced bronchoconstriction in asthmatic patients. Relation to histamine airway responsiveness and effect of preservative.
    Chest, 1989, Volume: 96, Issue:5

    Topics: Administration, Inhalation; Adult; Anesthesia, Local; Asthma; Bronchi; Bronchial Provocation Tests;

1989

Other Studies

57 other studies available for lidocaine and Asthma, Bronchial

ArticleYear
Hitting a nerve to ease asthma.
    Lab animal, 2015, Volume: 44, Issue:8

    Topics: Anesthetics, Local; Animals; Asthma; Bronchial Spasm; Inflammation; Lidocaine; Lung; Mice; Nocicepto

2015
A case of severe NSAID exacerbated respiratory disease (NERD) following a dental procedure in a child.
    European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, 2016, Volume: 17, Issue:4

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Cyclooxygenase 2 Inhibitors; Drug Hyper

2016
Bronchospasm after intravenous lidocaine.
    Anesthesia and analgesia, 2008, Volume: 107, Issue:4

    Topics: Anesthetics, Local; Asthma; Bronchial Spasm; Female; Humans; Infant; Injections, Intravenous; Intuba

2008
Two for one: cyclic AMP mediates the anti-inflammatory and anti-spasmodic properties of the non-anesthetic lidocaine analog JMF2-1.
    European journal of pharmacology, 2012, Apr-05, Volume: 680, Issue:1-3

    Topics: Adenylyl Cyclases; Animals; Anti-Inflammatory Agents; Apoptosis; Asthma; Carbachol; Caspase 8; Cell

2012
Nebulized lidocaine prevents airway inflammation, peribronchial fibrosis, and mucus production in a murine model of asthma.
    Anesthesiology, 2012, Volume: 117, Issue:3

    Topics: Anesthetics, Local; Animals; Asthma; Bronchi; Disease Models, Animal; Fibrosis; GATA3 Transcription

2012
Local anesthetics, neuraxial anesthesia, and the Brugada syndrome.
    Journal of clinical anesthesia, 2013, Volume: 25, Issue:1

    Topics: Anesthesia, Conduction; Anesthetics, Local; Asthma; Brugada Syndrome; Humans; Intestine, Small; Lido

2013
[STUDIES ON THE ACETYLCHOLINE- ANTAGONISTIC EFFECTS OF GLUCOCORTICOID ESTERS].
    Allergie und Asthma, 1963, Volume: 9

    Topics: Acetylcholine; Anti-Allergic Agents; Asthma; Cholinergic Antagonists; Dexamethasone; Esters; Glucoco

1963
[BRONCHIAL ASTHMA AS A RESULT OF LIDOCAINE ALLERGY].
    Allergie und Asthma, 1963, Volume: 9

    Topics: Asthma; Drug Hypersensitivity; Humans; Lidocaine; Sinusitis; Skin Tests; Surgical Procedures, Operat

1963
[STIMULATION OF HYPOTHALAMO-HYPOPHYSIAL SECRETIONS IN MAN BY RETRO-STYLOID ANESTHETIC INFILTRATION].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1963, Sep-10, Volume: 39

    Topics: Adrenocorticotropic Hormone; Anesthetics; Asthma; Autonomic Nerve Block; Eczema; Endocrinology; Huma

1963
ANAESTHESIA FOR GLOMECTOMY IN THE ASTHMATIC PATIENT.
    Canadian Anaesthetists' Society journal, 1964, Volume: 11

    Topics: Adolescent; Adrenal Cortex Hormones; Anesthesia; Anesthesia, Inhalation; Anesthesia, Local; Anesthes

1964
CATARACT EXTRACTION UNDER COMBINED LOCAL AND GENERAL ANALGESIA USING PHENAZOCINE.
    The British journal of ophthalmology, 1964, Volume: 48

    Topics: Analgesia; Anesthesia; Anesthesia, Intravenous; Anesthesia, Local; Asthma; Bronchitis; Cataract Extr

1964
Airway management in acute respiratory distress secondary to tracheal stenosis following one time intubation.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2004, Volume: 51, Issue:4

    Topics: Adolescent; Analgesics; Anesthesia, Inhalation; Anesthetics, Local; Asthma; Emergency Treatment; Fib

2004
Bronchial epilepsy or broncho-pulmonary hyper-excitability as a model of asthma pathogenesis.
    Medical hypotheses, 2006, Volume: 67, Issue:5

    Topics: Airway Obstruction; Asthma; Bronchi; Bronchial Hyperreactivity; Cell Membrane; gamma-Aminobutyric Ac

2006
Identification of independent risk factors for fentanyl-induced cough.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2006, Volume: 53, Issue:8

    Topics: Adult; Age Factors; Anesthesia, Epidural; Anesthetics, Intravenous; Anesthetics, Local; Angiotensin-

2006
[A pregnant woman with severe asthma effectively treated by inhalational lidocaine therapy].
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2006, Volume: 44, Issue:11

    Topics: Administration, Inhalation; Adult; Asthma; Female; Humans; Lidocaine; Nebulizers and Vaporizers; Pre

2006
The effects of systemic lidocaine on airway tone and pulmonary function in asthmatic subjects.
    Anesthesia and analgesia, 2007, Volume: 104, Issue:5

    Topics: Adolescent; Adult; Asthma; Bronchoconstriction; Female; Humans; Infusions, Intravenous; Lidocaine; L

2007
Dental anesthesia with lidocaine hydrochloride for children with intractable asthma and associated allergies.
    Journal of oral therapeutics and pharmacology, 1967, Volume: 3, Issue:6

    Topics: Adolescent; Anesthesia, Dental; Anesthesia, Local; Asthma; Child; Child, Institutionalized; Dentistr

1967
Effect of inspiratory flow rate on bronchomotor tone in normal and asthmatic subjects.
    Thorax, 1984, Volume: 39, Issue:2

    Topics: Adult; Airway Resistance; Asthma; Bronchi; Bronchial Provocation Tests; Bronchospirometry; Female; H

1984
Mechanism of cough and bronchoconstriction induced by distilled water aerosol.
    The American review of respiratory disease, 1983, Volume: 127, Issue:6

    Topics: Adolescent; Adult; Aerosols; Airway Resistance; Asthma; Bronchi; Bronchial Spasm; Cough; Cromolyn So

1983
[Effect of lidocaine on histamine-induced bronchial spasm].
    Pneumonologia polska, 1983, Volume: 51, Issue:12

    Topics: Adult; Aged; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Female; Histamine; Histamine Anta

1983
Comparison of local anesthetics as bronchodilator aerosols.
    Anesthesiology, 1983, Volume: 58, Issue:3

    Topics: Anesthetics, Local; Animals; Asthma; Bronchi; Bronchial Provocation Tests; Bronchodilator Agents; Bu

1983
Controlled-analysis of the effects of inhaled lignocaine in exercise-induced asthma.
    Thorax, 1982, Volume: 37, Issue:10

    Topics: Adult; Aerosols; Asthma; Asthma, Exercise-Induced; Female; Humans; Lidocaine; Lung; Male

1982
A reassessment of the effects of oropharyngeal anesthesia in exercise-induced asthma.
    The American review of respiratory disease, 1980, Volume: 122, Issue:3

    Topics: Adult; Asthma; Asthma, Exercise-Induced; Efferent Pathways; Female; Forced Expiratory Volume; Humans

1980
[Prolonged peridural block in the overall treatment of the infectious-allergic form of bronchial asthma].
    Vestnik khirurgii imeni I. I. Grekova, 1980, Volume: 125, Issue:8

    Topics: Adolescent; Adult; Aged; Anesthesia, Epidural; Asthma; Evaluation Studies as Topic; Female; Humans;

1980
Effect of lidocaine on the ventilatory and airway responses to exercise in asthmatics.
    The American review of respiratory disease, 1980, Volume: 122, Issue:6

    Topics: Adolescent; Adult; Airway Resistance; Asthma; Child; Female; Humans; Lidocaine; Lung; Lung Volume Me

1980
No support for intravenous lidocaine airway reflex suppression during rapid sequence intubation.
    Annals of emergency medicine, 1995, Volume: 26, Issue:5

    Topics: Asthma; Cough; Drug Therapy, Combination; Humans; Infusions, Intravenous; Intubation, Intratracheal;

1995
Tracheal lidocaine stops airway hyperresponsiveness.
    Annals of emergency medicine, 1995, Volume: 25, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Asthma; Female; Humans; Lidocaine; Male; Respiratory Insufficiency;

1995
Anaesthetic management of an asthmatic child for appendicectomy.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1994, Volume: 41, Issue:6

    Topics: Adolescent; Albuterol; Anesthesia, Epidural; Appendectomy; Asthma; Beclomethasone; Bupivacaine; Fent

1994
Lidocaine and rapid sequence intubation.
    Annals of emergency medicine, 1996, Volume: 27, Issue:4

    Topics: Anesthetics, Local; Asthma; Bronchial Spasm; Humans; Intubation, Intratracheal; Lidocaine

1996
Lidocaine in bronchoalveolar lavage fluid (BALF) is an inhibitor of eosinophil-active cytokines.
    Clinical and experimental immunology, 1996, Volume: 104, Issue:2

    Topics: Adult; Aged; Anesthetics, Local; Asthma; Bronchoalveolar Lavage Fluid; Cell Survival; Cytokines; Eos

1996
Effect of nebulized lidocaine on severe glucocorticoid-dependent asthma.
    Mayo Clinic proceedings, 1996, Volume: 71, Issue:4

    Topics: Administration, Inhalation; Adult; Aged; Asthma; Bronchodilator Agents; Female; Glucocorticoids; Hum

1996
Lidocaine and oral mexiletine block reflex bronchoconstriction in asthmatic subjects.
    American journal of respiratory and critical care medicine, 1997, Volume: 156, Issue:5

    Topics: Administration, Oral; Aerosols; Anesthetics, Local; Asthma; Bronchoconstriction; Humans; Injections,

1997
Nebulized lidocaine in the treatment of severe asthma in children: a pilot study.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 1999, Volume: 82, Issue:1

    Topics: Administration, Inhalation; Adolescent; Adrenocortical Hyperfunction; Asthma; Child; Female; Glucoco

1999
Anaesthesia for LSCS in a morbidly obese patient.
    Anaesthesia and intensive care, 1999, Volume: 27, Issue:2

    Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthetics, Local; Asthma; Body Mass Index; C

1999
Pretreatment intravenous lidocaine for intubation of the asthmatic patient: more data are needed.
    Anesthesiology, 1999, Volume: 91, Issue:1

    Topics: Anesthetics, Local; Asthma; Bronchoconstriction; Histamine; Humans; Intubation, Intratracheal; Lidoc

1999
Serum lidocaine concentrations in asthmatics undergoing research bronchoscopy.
    Chest, 2000, Volume: 117, Issue:4

    Topics: Academic Medical Centers; Administration, Topical; Adult; Anesthesia, Local; Anesthetics, Local; Ast

2000
Lidocaine nebulization for treatment of asthma.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2000, Volume: 85, Issue:3

    Topics: Asthma; Child; Humans; Lidocaine; Male; Nebulizers and Vaporizers

2000
Lidocaine inhalation for cough suppression.
    The American journal of emergency medicine, 2001, Volume: 19, Issue:3

    Topics: Administration, Inhalation; Adult; Aged; Albuterol; Anesthetics, Local; Antitussive Agents; Asthma;

2001
Sensitivity to local anaesthetics among asthmatic children.
    International journal of paediatric dentistry, 2001, Volume: 11, Issue:6

    Topics: Adolescent; Allergens; Anesthetics, Local; Animals; Asthma; Child; Drug Hypersensitivity; Female; Hu

2001
Inhibitory effect of lidocaine on T cells from patients with allergic asthma.
    The Journal of allergy and clinical immunology, 2002, Volume: 109, Issue:3

    Topics: Allergens; Animals; Anti-Inflammatory Agents; Asthma; CD4-Positive T-Lymphocytes; Cytokines; Dexamet

2002
Effects of inhaled lidocaine on airway function in asthmatic subjects.
    Respiration; international review of thoracic diseases, 1979, Volume: 37, Issue:4

    Topics: Adult; Aerosols; Anesthesia, Inhalation; Asthma; Atropine; Bronchial Spasm; Female; Forced Expirator

1979
A comparison of immunologic asthma to two types of cholinergic respiratory responses in the rhesus monkey.
    The Journal of laboratory and clinical medicine, 1976, Volume: 88, Issue:6

    Topics: Acetylcholine; Aerosols; Airway Resistance; Animals; Antigens; Ascaris; Asthma; Atropine; Carbachol;

1976
[Intensive acre and resuscitation in bronchial asthma and the asthmatic state].
    Terapevticheskii arkhiv, 1975, Volume: 47, Issue:8

    Topics: Acidosis; Adolescent; Adult; Aminophylline; Anesthesia; Asthma; Critical Care; Droperidol; Ephedrine

1975
Substance p-induced cutaneous and bronchial reactions in children with bronchial asthma.
    Annals of allergy, 1991, Volume: 66, Issue:2

    Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Child; Child, Preschool; Erythema; Female; F

1991
Pharmacologic control of plasma exudation into tracheobronchial airways.
    The American review of respiratory disease, 1991, Volume: 143, Issue:5 Pt 1

    Topics: Animals; Asthma; Bronchi; Bronchodilator Agents; Capillary Permeability; Cromolyn Sodium; Guinea Pig

1991
Flexible fiberoptic bronchoscopy does not alter airway responsiveness.
    Respiration; international review of thoracic diseases, 1989, Volume: 56, Issue:3-4

    Topics: Adult; Asthma; Atropine; Bronchi; Bronchial Provocation Tests; Bronchoscopy; Fiber Optic Technology;

1989
Effects of inhaled lidocaine on exercise-induced asthma.
    Respiration; international review of thoracic diseases, 1987, Volume: 51, Issue:2

    Topics: Administration, Inhalation; Adolescent; Adult; Aerosols; Asthma; Asthma, Exercise-Induced; Female; H

1987
Leukotrienes (LTC4, LTD4) confer glass non-adherence on leukocytes of asthmatic individuals. Dependency on cyclooxygenase products and calcium ion.
    Immunology letters, 1985, Volume: 10, Issue:6

    Topics: Asthma; Calcium; Cell Adhesion; Child; Cyclooxygenase Inhibitors; Dinoprostone; Glass; Humans; Indom

1985
Anti-asthma drugs and capsaicine-induced microvascular effects in lower airways.
    Agents and actions, 1985, Volume: 16, Issue:1-2

    Topics: Animals; Asthma; Bronchodilator Agents; Capillary Permeability; Capsaicin; Guinea Pigs; Lidocaine; M

1985
[Bronchial asthma and neural therapy (author's transl)].
    Wiener klinische Wochenschrift, 1974, Feb-22, Volume: 86, Issue:4

    Topics: Adult; Asthma; Child, Preschool; Cicatrix; Female; Humans; Immunotherapy; Injections, Intradermal; L

1974
Local anaesthetic sensitivity. Case report.
    Australian dental journal, 1972, Volume: 17, Issue:1

    Topics: Antigen-Antibody Reactions; Asthma; Drug Hypersensitivity; Edema; Epinephrine; Female; Humans; Hyper

1972
The effect of environmental temperature on airway resistance in the asthmatic child.
    Pediatric research, 1973, Volume: 7, Issue:7

    Topics: Adolescent; Airway Resistance; Anesthesia, Local; Asthma; Bronchi; Child; Chronic Disease; Cold Temp

1973
Bronchial lavage in asthma and bronchitis.
    Annals of allergy, 1972, Volume: 30, Issue:9

    Topics: Asthma; Bronchitis; Bronchoscopy; Catheterization; Halothane; Humans; Isotonic Solutions; Lidocaine;

1972
[Allergic skin reactions to topical anesthetics in patients with bronchial asthma].
    Czasopismo stomatologiczne, 1971, Volume: 24, Issue:5

    Topics: Asthma; Drug Hypersensitivity; Humans; Lidocaine; Procaine; Skin Tests

1971
Severe bronchospasm complicating thoracotomy.
    Archives of surgery (Chicago, Ill. : 1960), 1970, Volume: 101, Issue:5

    Topics: Adult; Asthma; Bronchial Spasm; Female; Humans; Lidocaine; Male; Mitral Valve Insufficiency; Mitral

1970
Circulatory and respiratory changes during unilateral and bilateral cranial nerve IX and X block in two asthmatics.
    Clinical science, 1971, Volume: 40, Issue:2

    Topics: Adult; Anesthesia, Conduction; Anilides; Asthma; Blood Pressure; Carbon Dioxide; Cranial Nerves; Fem

1971
[Bronchoscopic sanitation in the treatment of chronic pneumonia with an asthmatic component].
    Vestnik khirurgii imeni I. I. Grekova, 1971, Volume: 106, Issue:1

    Topics: Asthma; Bronchoscopy; Child; Chronic Disease; Drainage; Humans; Lidocaine; Pneumonia; Povidone; Ther

1971