lidocaine has been researched along with Anxiety in 92 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study evaluated the analgesic efficacy and emotional response to intravenous lidocaine infusion compared with placebo in patients with postherpetic neuralgia (PHN)." | 9.27 | The Analgesic and Emotional Response to Intravenous Lidocaine Infusion in the Treatment of Postherpetic Neuralgia: A Randomized, Double-Blinded, Placebo-controlled Study. ( Li, J; Liu, H; Lu, F; Song, L; Xiao, H; Yang, B; Ye, L; Yin, Y; Zhou, D, 2018) |
| "The group that was premedicated with dextromethorphan had lower complaint scores, significantly less coughing, significantly less stress assessed by the patient and the physician evaluation, shorter total procedure time, and fewer midazolam requirements during FB (P-value <0." | 9.24 | The Effect of Dextromethorphan Premedication on Cough and Patient Tolerance During Flexible Bronchoscopy: A Randomized, Double-blind, Placebo-controlled Trial. ( Amini, S; Ghalamkari, M; Khatuni, M; Peiman, S; Rahimi, B, 2017) |
| " Patient anxiety levels were measured 24 hours pre-operatively; 48 hours post-operatively, before saline or lidocaine infiltration; and 15 minutes after lidocaine or saline infiltration into the packing." | 9.20 | Effect on patient anxiety of lidocaine infiltration into nasal packing after septoplasty: prospective, controlled study. ( Aras, HI; Sahin, C, 2015) |
| " In this study, the efficacy of local lidocaine application on anxiety and depression and its curative effect in patients with chronic TTH was investigated." | 9.17 | Efficacy of local lidocaine application on anxiety and depression and its curative effect on patients with chronic tension-type headache. ( Inan, LE; Karadaş, Ö; Odabaşi, Z; Ulaş, Ü, 2013) |
| " High dose intravenous opioids form the mainstay of procedural burns pain management; however it was suggested that intravenous lidocaine assists with minimising the pain experience." | 9.15 | Adjuvant use of intravenous lidocaine for procedural burn pain relief: a randomized double-blind, placebo-controlled, cross-over trial. ( Cleland, H; Costello, V; Ferraro, F; Konstantatos, A; Paul, E; Spinks, A; Wasiak, J, 2011) |
| "To evaluate five different preoperative anxiolytic regimens in cataract surgery performed under regional anesthesia; to quantify the pain associated with combined peri- and retrobulbar injection (PRBI) of local anesthetic drugs; and to describe a technique of painless eye block." | 9.08 | Evaluation of anxiolysis and pain associated with combined peri- and retrobulbar eye block for cataract surgery. ( Berry, RA; Boezaart, AP; Laubscher, JJ; Nell, ML, 1998) |
| "To assess the efficacy of 4% topical lidocaine in spheno-palatine blocks, a randomized controlled trial was carried out on patients with chronic muscle pain syndromes." | 9.08 | The use of topical 4% lidocaine in spheno-palatine ganglion blocks for the treatment of chronic muscle pain syndromes: a randomized, controlled trial. ( Delaney, G; Heck, C; Janzen, V; McCain, GA; Russell, AL; Scudds, RA; Teasell, RW; Varkey, G; Woodbury, GM, 1995) |
| "The local analgesic efficacy of a cream formulation of lidocaine and prilocaine (EMLA) in reducing pain at venous cannulation was investigated in children scheduled for elective surgery." | 9.06 | Reduction of pain at venous cannulation in children with a eutectic mixture of lidocaine and prilocaine (EMLA cream): comparison with placebo cream and no local premedication. ( Iisalo, E; Kanto, J; Lindberg, R; Manner, T; Scheinin, M; Viinamäki, O, 1987) |
| " Prior to the procedure, subjects rated anxiety on a numerical rating scale (NRS) from 0 (no anxiety) to 3 (extreme anxiety), and received standardized subcutaneous injections of lidocaine (using 25-G needle to infiltrate 2 cc 1% lidocaine) as local anesthesia." | 7.77 | Judging pain sensitivity with subcutaneous lidocaine injections. ( Hunt, P; Manabat, ER; Pujol, LA; Wang, D, 2011) |
| "Intent-to-treat multilevel analyses showed that for women, CBCT yielded significantly more improvements than lidocaine in pain unpleasantness at 6-month follow-up, pain anxiety and pain catastrophizing at post-treatment and 6-month follow-up, and sexual distress at post-treatment, and resulted in better treatment satisfaction and global sexuality improvements at both time points." | 5.41 | Cognitive-behavioral couple therapy versus lidocaine for provoked vestibulodynia: A randomized clinical trial. ( Bergeron, S; Corsini-Munt, S; Delisle, I; Mayrand, MH; Rosen, NO; Steben, M; Vaillancourt-Morel, MP, 2021) |
| "This was secondary analysis of prospectively obtained data from a randomized controlled trial comparing vapocoolant spray with jet-injected lidocaine for venipuncture pain." | 5.41 | An Evaluation of High Preprocedural Anxiety and Venipuncture Pain Experienced by Young Children. ( Bolin, AE; Drendel, AL; Lunoe, MM, 2021) |
| "Adjuvant oral hydrocodone/acetaminophen is more effective than placebo in reducing pain in children younger than 8 years undergoing topical lidocaine-treated laceration repair, but it does not decrease pain or anxiety in older children." | 5.34 | Evaluation of Hydrocodone/Acetaminophen for Pediatric Laceration Repair: A Randomized Trial. ( Camp, EA; Caviness, AC; Chumpitazi, CE; Grawe, GH; Shah, MI, 2020) |
| "This study evaluated the analgesic efficacy and emotional response to intravenous lidocaine infusion compared with placebo in patients with postherpetic neuralgia (PHN)." | 5.27 | The Analgesic and Emotional Response to Intravenous Lidocaine Infusion in the Treatment of Postherpetic Neuralgia: A Randomized, Double-Blinded, Placebo-controlled Study. ( Li, J; Liu, H; Lu, F; Song, L; Xiao, H; Yang, B; Ye, L; Yin, Y; Zhou, D, 2018) |
| "The group that was premedicated with dextromethorphan had lower complaint scores, significantly less coughing, significantly less stress assessed by the patient and the physician evaluation, shorter total procedure time, and fewer midazolam requirements during FB (P-value <0." | 5.24 | The Effect of Dextromethorphan Premedication on Cough and Patient Tolerance During Flexible Bronchoscopy: A Randomized, Double-blind, Placebo-controlled Trial. ( Amini, S; Ghalamkari, M; Khatuni, M; Peiman, S; Rahimi, B, 2017) |
| "Lidocaine gel and spray combination is the most ideal pharyngeal anesthesia to ensure the adaptation of the patient to the procedure and to decrease anxiety and discomfort during the procedure." | 5.22 | Study of ideal topical pharyngeal anesthesia in upper gastrointestinal system endoscopy: A double-blind, randomized, controlled trial. ( Çam, H; Dağ, MS; Demir, U; Gülşen, MT; Pehlivan, S; Yılmaz, N, 2016) |
| "4 mL of 2% lidocaine with epinephrine neither caused hyperglycemia nor had any significant impact on hemodynamic or anxiety parameters." | 5.20 | Local anesthesia with epinephrine is safe and effective for oral surgery in patients with type 2 diabetes mellitus and coronary disease: a prospective randomized study. ( Neves, IL; Neves, RS; Ramires, JA; Santos-Paul, MA, 2015) |
| " In this study, the efficacy of local lidocaine application on anxiety and depression and its curative effect in patients with chronic TTH was investigated." | 5.17 | Efficacy of local lidocaine application on anxiety and depression and its curative effect on patients with chronic tension-type headache. ( Inan, LE; Karadaş, Ö; Odabaşi, Z; Ulaş, Ü, 2013) |
| " High dose intravenous opioids form the mainstay of procedural burns pain management; however it was suggested that intravenous lidocaine assists with minimising the pain experience." | 5.15 | Adjuvant use of intravenous lidocaine for procedural burn pain relief: a randomized double-blind, placebo-controlled, cross-over trial. ( Cleland, H; Costello, V; Ferraro, F; Konstantatos, A; Paul, E; Spinks, A; Wasiak, J, 2011) |
| "We compare pain and anxiety associated with peripheral intravenous (IV) cannula insertion after pretreatment with no local anesthesia, 4% lidocaine cream, or subcutaneously injected, buffered 1% lidocaine." | 5.14 | A randomized, crossover comparison of injected buffered lidocaine, lidocaine cream, and no analgesia for peripheral intravenous cannula insertion. ( Kennedy, R; McNaughton, C; Robert, L; Storrow, A; Zhou, C, 2009) |
| "Infiltration anaesthesia with articaine, a local anaesthetic able to penetrate bone, may relieve procedural pain better than lidocaine in bone marrow aspiration and biopsy." | 5.14 | Comparison of articaine and lidocaine for infiltration anaesthesia in patients undergoing bone marrow aspiration and biopsy. ( Elonen, E; Kuivalainen, AM; Niemi-Murola, L; Rosenberg, PH; Widenius, T, 2010) |
| "Subjective measures of pain intensity and the total pain experience were greater with lidocaine vaginal gel compared with lidocaine paracervical block." | 5.11 | Lidocaine vaginal gel versus lidocaine paracervical block for analgesia during oocyte retrieval. ( Lee, C; Martin, J; Newton, C; Tummon, I, 2004) |
| "The pretreatment with nitrous oxide is a time effective and safe method for use at paediatric outpatient departments to reduce pain, facilitate venous cannulation, and thereby reduce the number of costly cancellations of planned procedures." | 5.11 | Nitrous oxide inhalation is a safe and effective way to facilitate procedures in paediatric outpatient departments. ( Ekbom, K; Jakobsson, J; Marcus, C, 2005) |
| "These data show that cerebral protection by lidocaine, which is unrelated to any effect on depression or anxiety, and is at a level that is noticed by the patients." | 5.09 | Cerebral protection by lidocaine during cardiac operations. ( Gorman, DF; Mitchell, SJ; Pellett, O, 1999) |
| "The efficacy of lignocaine-prilocaine cream (EMLA) and amethocaine gel (Ametop) in reducing the pain and distress of venepuncture was compared in a single-blind randomized study of 34 children aged 1-14 y." | 5.09 | Comparison of lignocaine-prilocaine cream and amethocaine gel for local analgesia before venepuncture in children. ( Choy, L; Collier, J; Watson, AR, 1999) |
| "To assess the efficacy of 4% topical lidocaine in spheno-palatine blocks, a randomized controlled trial was carried out on patients with chronic muscle pain syndromes." | 5.08 | The use of topical 4% lidocaine in spheno-palatine ganglion blocks for the treatment of chronic muscle pain syndromes: a randomized, controlled trial. ( Delaney, G; Heck, C; Janzen, V; McCain, GA; Russell, AL; Scudds, RA; Teasell, RW; Varkey, G; Woodbury, GM, 1995) |
| "5% prilocaine) in reducing distress, anxiety, and pain associated with phlebotomy in pediatric outpatients." | 5.08 | EMLA cream as a topical anesthetic before office phlebotomy in children. ( Schwartz, R; Sheridan, MJ; Young, SS, 1996) |
| "To evaluate five different preoperative anxiolytic regimens in cataract surgery performed under regional anesthesia; to quantify the pain associated with combined peri- and retrobulbar injection (PRBI) of local anesthetic drugs; and to describe a technique of painless eye block." | 5.08 | Evaluation of anxiolysis and pain associated with combined peri- and retrobulbar eye block for cataract surgery. ( Berry, RA; Boezaart, AP; Laubscher, JJ; Nell, ML, 1998) |
| "Emla cream combined with nitrous oxide is effective for venous cannulation in providing satisfactory analgesia and in controlling anxiety elicited by the vision of needle." | 5.08 | [Combination of Emla cream and nitrous oxide for venous cannulation in children]. ( Benaguida, M; Benslama, A; Idali, B; Mjahed, K; Sadraoui, A, 1997) |
| "3 mg/kg) and buffered lidocaine in reducing the anxiety associated with the repair of childhood lacerations." | 5.08 | A randomized, controlled trial of oral midazolam and buffered lidocaine for suturing lacerations in children (the SLIC Trial). ( Fatovich, DM; Jacobs, IG, 1995) |
| "The local analgesic efficacy of EMLA Cream (a eutectic mixture of lidocaine and prilocaine; Astra Pharmaceuticals, Sweden) in reducing the pain at Venous cannulation was investigated in a randommized blind study in 75 children scheduled for elective surgery." | 5.06 | Our experience with EMLA Cream (for painless venous cannulation in children). ( Johl, KS; Wig, J, 1990) |
| "The local analgesic efficacy of a cream formulation of lidocaine and prilocaine (EMLA) in reducing pain at venous cannulation was investigated in children scheduled for elective surgery." | 5.06 | Reduction of pain at venous cannulation in children with a eutectic mixture of lidocaine and prilocaine (EMLA cream): comparison with placebo cream and no local premedication. ( Iisalo, E; Kanto, J; Lindberg, R; Manner, T; Scheinin, M; Viinamäki, O, 1987) |
| "Although lidocaine alone will serve as an excellent anesthetic for most patients, using less painful injectable agents, topical anesthetics, and occasionally oral sedation will offer the frightened or pain-intolerant patient an acceptable and effective alternative system of local anesthesia." | 4.79 | Choosing a local anesthetic. ( Holmes, HS, 1994) |
| "In this cohort study, we surveyed 30 adolescents and young adults at their implant insertion visit about pre-procedure anxiety and pain experienced during lidocaine injection and Nexplanon™ placement." | 4.02 | A Pilot Study to Understand the Adolescent Pain Experience During Contraceptive Implant Insertion. ( Bentsianov, SD; Brandi, K; Chen, P; Shimoni, N, 2021) |
| " Here, we examine the effects of experimental lidocaine-induced anosmia on anxiety-like behavior and whole-body cortisol levels in adult zebrafish (Danio rerio)." | 3.83 | The smell of "anxiety": Behavioral modulation by experimental anosmia in zebrafish. ( Abreu, MS; Barcellos, LJ; Giacomini, AC; Kalueff, AV, 2016) |
| " Prior to the procedure, subjects rated anxiety on a numerical rating scale (NRS) from 0 (no anxiety) to 3 (extreme anxiety), and received standardized subcutaneous injections of lidocaine (using 25-G needle to infiltrate 2 cc 1% lidocaine) as local anesthesia." | 3.77 | Judging pain sensitivity with subcutaneous lidocaine injections. ( Hunt, P; Manabat, ER; Pujol, LA; Wang, D, 2011) |
| " Temporary inactivation of fimbria-fornix with lidocaine 4% promoted an anxiolytic-like effect per se, suggesting a tonic control of this pathway on the modulation of anxiety-related behaviors." | 3.76 | Short- and long-term anxiogenic effects induced by a single injection of subconvulsant doses of pilocarpine in rats: investigation of the putative role of hippocampal pathways. ( Canteras, NS; De Lima, TC; Duarte, FS; Duzzioni, M; Gavioli, EC; Hoeller, AA, 2010) |
| " In contrast, pain intensity evaluated by the patient tended to be lower in the Entonox group (mean VAS: 2." | 3.74 | [Value of nitrous oxide-oxygen mixture (Entonox) in transrectal prostate biopsies]. ( Dubruille, T; Michel, F; Spie, R; Watfa, J, 2008) |
| "Some children report significant pain with peripheral intravenous catheter (IV) insertion, despite the appropriate use of topical lidocaine anesthetics." | 3.74 | Predictors of topical anesthetic effectiveness in children. ( Floria-Santos, M; Hanrahan, K; Kleiber, C; McCarthy, AM; Murray, JC; Schutte, DL, 2007) |
| "Provoked vestibulodynia (PVD) is a highly prevalent and debilitating condition yet its management relies mainly on non-empirically validated interventions." | 2.82 | Randomized clinical trial of multimodal physiotherapy treatment compared to overnight lidocaine ointment in women with provoked vestibulodynia: Design and methods. ( Bergeron, S; Dubois, MF; Dumoulin, C; Khalifé, S; Mayrand, MH; Morin, M; Waddell, G, 2016) |
| "Pain was assessed by visual analogue scale (VAS) and anxiety levels by the State-Trait Anxiety Inventory (STAI-I and STA-II)." | 2.77 | No effect of perianal application of topical anaesthetic on patient comfort during nonsedated flexible sigmoidoscopy: a randomized, placebo-controlled clinical trial. ( Boyacioglu, S; Cengiz, C; Kuzu, MA; Ozdemir, B; Pampal, HK, 2012) |
| "Heat facial hyperalgesia was assessed on day 6 after the inoculation, and on this time point rats were submitted to the elevated plus maze and the light-dark transition tests." | 1.43 | Evaluation of heat hyperalgesia and anxiety like-behaviors in a rat model of orofacial cancer. ( Chichorro, JG; Dos Reis, RC; Gambeta, E; Kopruszinski, CM; Zanoveli, JM, 2016) |
| "We tested the hypothesis that ulcerative colitis-like inflammation induced by dextran sodium sulfate (DSS) exacerbates the ongoing spontaneous activity in colon-projecting afferent neurons that induces abdominal discomfort and anxiety, and depressive-like behaviors in rats." | 1.42 | Genesis of anxiety, depression, and ongoing abdominal discomfort in ulcerative colitis-like colon inflammation. ( Chen, J; Fu, Y; Green, TA; Guptarak, J; Jensen, KL; Sarna, SK; Shi, XZ; Winston, JH, 2015) |
| "FNAC-related pain is frequent and correlates with the number of nodules biopsied, age under 25 years, female sex, and anxiety." | 1.39 | Frequency and intensity of pain related to thyroid nodule fine-needle aspiration cytology. ( Azoulay, S; Baudin, E; Berdelou, A; Bidault, S; Borget, I; Chougnet, CN; Dauchy, S; Deandreis, D; Girard, E; Hartl, D; Labro, S; Laurent, S; Leboulleux, S; Lumbroso, J; Mirghani, H; Schlumberger, M; Vielh, P, 2013) |
| "In fact, the nurse coached more, and trends suggested that children coped more with typical care than with EMLA." | 1.30 | Comparative study of distraction versus topical anesthesia for pediatric pain management during immunizations. ( Blount, RL; Cohen, LL; Cohen, RJ; Schaen, ER; Zaff, JF, 1999) |
| "In a study of 7 cases of adverse reactions to local anaesthetics the early symptoms of toxicity (malaise, anxiety, feeling of impending death, peripheral paresthesias and tachycardia) are reviewed." | 1.26 | [Minor toxic effects of local anaesthetics. 7 cases (author's transl)]. ( Dry, J; Leynadier, F, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (9.78) | 18.7374 |
| 1990's | 24 (26.09) | 18.2507 |
| 2000's | 22 (23.91) | 29.6817 |
| 2010's | 30 (32.61) | 24.3611 |
| 2020's | 7 (7.61) | 2.80 |
| Authors | Studies |
|---|---|
| Lunoe, MM | 1 |
| Bolin, AE | 1 |
| Drendel, AL | 1 |
| França, AJB | 1 |
| Barbirato, DDS | 1 |
| Vasconcellos, RJH | 1 |
| Pellizzer, EP | 1 |
| Moraes, SLD | 1 |
| Vasconcelos, BCDE | 1 |
| Chumpitazi, CE | 1 |
| Caviness, AC | 1 |
| Grawe, GH | 1 |
| Camp, EA | 1 |
| Shah, MI | 1 |
| Tripathi, SJ | 2 |
| Chakraborty, S | 2 |
| Rao, BSS | 1 |
| Bentsianov, SD | 1 |
| Brandi, K | 1 |
| Chen, P | 1 |
| Shimoni, N | 1 |
| Seyhan Ak, E | 1 |
| Culha, Y | 1 |
| Culha, MG | 1 |
| Ozer, M | 1 |
| Ozbas, A | 1 |
| Bergeron, S | 2 |
| Vaillancourt-Morel, MP | 1 |
| Corsini-Munt, S | 1 |
| Steben, M | 1 |
| Delisle, I | 1 |
| Mayrand, MH | 2 |
| Rosen, NO | 1 |
| Amini, S | 1 |
| Peiman, S | 1 |
| Khatuni, M | 1 |
| Ghalamkari, M | 1 |
| Rahimi, B | 1 |
| Liu, H | 1 |
| Lu, F | 1 |
| Zhou, D | 1 |
| Yin, Y | 1 |
| Li, J | 1 |
| Yang, B | 1 |
| Song, L | 1 |
| Ye, L | 1 |
| Xiao, H | 1 |
| Srikumar, BN | 1 |
| Raju, TR | 1 |
| Shankaranarayana Rao, BS | 1 |
| de Abreu, MS | 1 |
| Giacomini, ACVV | 1 |
| Dos Santos, BE | 1 |
| Genario, R | 1 |
| Marchiori, NI | 1 |
| Rosa, LGD | 1 |
| Kalueff, AV | 2 |
| Karadaş, Ö | 1 |
| Inan, LE | 1 |
| Ulaş, Ü | 1 |
| Odabaşi, Z | 1 |
| Atalay, NS | 1 |
| Sahin, F | 1 |
| Atalay, A | 1 |
| Akkaya, N | 1 |
| Zhang, ZS | 1 |
| Wang, XL | 1 |
| Xu, CL | 1 |
| Zhang, C | 1 |
| Cao, Z | 1 |
| Xu, WD | 1 |
| Wei, RC | 1 |
| Sun, YH | 1 |
| Chen, J | 1 |
| Winston, JH | 1 |
| Fu, Y | 1 |
| Guptarak, J | 1 |
| Jensen, KL | 1 |
| Shi, XZ | 1 |
| Green, TA | 1 |
| Sarna, SK | 1 |
| Laurent, B | 1 |
| Vicaut, E | 1 |
| Leplège, A | 1 |
| Bloch, K | 1 |
| Leutenegger, E | 1 |
| Chang, YH | 1 |
| Oh, TH | 1 |
| Lee, JW | 1 |
| Park, SC | 1 |
| Seo, IY | 1 |
| Jeong, HJ | 1 |
| Kwon, WA | 1 |
| Santos-Paul, MA | 1 |
| Neves, IL | 1 |
| Neves, RS | 1 |
| Ramires, JA | 1 |
| Sahin, C | 1 |
| Aras, HI | 1 |
| Morin, M | 1 |
| Dumoulin, C | 1 |
| Khalifé, S | 1 |
| Waddell, G | 1 |
| Dubois, MF | 1 |
| Abreu, MS | 1 |
| Giacomini, AC | 1 |
| Barcellos, LJ | 1 |
| Çam, H | 1 |
| Pehlivan, S | 1 |
| Dağ, MS | 1 |
| Yılmaz, N | 1 |
| Demir, U | 1 |
| Gülşen, MT | 1 |
| Gambeta, E | 1 |
| Kopruszinski, CM | 1 |
| Dos Reis, RC | 1 |
| Zanoveli, JM | 1 |
| Chichorro, JG | 1 |
| Dalvandi, A | 1 |
| Ranjbar, H | 1 |
| Hatamizadeh, M | 1 |
| Rahgoi, A | 1 |
| Bernstein, C | 1 |
| Spie, R | 1 |
| Watfa, J | 1 |
| Dubruille, T | 1 |
| Michel, F | 1 |
| McNaughton, C | 1 |
| Zhou, C | 1 |
| Robert, L | 1 |
| Storrow, A | 1 |
| Kennedy, R | 1 |
| Kuivalainen, AM | 1 |
| Niemi-Murola, L | 1 |
| Widenius, T | 1 |
| Elonen, E | 1 |
| Rosenberg, PH | 1 |
| Lamprea, MR | 1 |
| Garcia, AM | 1 |
| Morato, S | 1 |
| Carson, C | 1 |
| Wyllie, M | 1 |
| Duarte, FS | 1 |
| Gavioli, EC | 1 |
| Duzzioni, M | 1 |
| Hoeller, AA | 1 |
| Canteras, NS | 1 |
| De Lima, TC | 1 |
| Chiaretti, A | 1 |
| Barone, G | 2 |
| Rigante, D | 1 |
| Ruggiero, A | 1 |
| Pierri, F | 1 |
| Barbi, E | 1 |
| Riccardi, R | 1 |
| Manabat, ER | 1 |
| Pujol, LA | 1 |
| Hunt, P | 1 |
| Wang, D | 1 |
| Wasiak, J | 1 |
| Spinks, A | 1 |
| Costello, V | 1 |
| Ferraro, F | 1 |
| Paul, E | 1 |
| Konstantatos, A | 1 |
| Cleland, H | 1 |
| Cengiz, C | 1 |
| Pampal, HK | 1 |
| Ozdemir, B | 1 |
| Boyacioglu, S | 1 |
| Kuzu, MA | 1 |
| Berger, A | 1 |
| Sadosky, A | 1 |
| Dukes, E | 1 |
| Edelsberg, J | 1 |
| Oster, G | 1 |
| Beiderbeck, DI | 1 |
| Reber, SO | 1 |
| Havasi, A | 1 |
| Bredewold, R | 1 |
| Veenema, AH | 1 |
| Neumann, ID | 1 |
| Polat, F | 1 |
| Tuncel, A | 2 |
| Balci, M | 1 |
| Aslan, Y | 2 |
| Sacan, O | 1 |
| Kisa, C | 2 |
| Kayali, M | 1 |
| Atan, A | 2 |
| Teo, I | 1 |
| Lam, W | 1 |
| Muthayya, P | 1 |
| Steele, K | 1 |
| Alexander, S | 1 |
| Miller, G | 1 |
| Leboulleux, S | 1 |
| Borget, I | 1 |
| Labro, S | 1 |
| Bidault, S | 1 |
| Vielh, P | 1 |
| Hartl, D | 1 |
| Dauchy, S | 1 |
| Chougnet, CN | 1 |
| Girard, E | 1 |
| Azoulay, S | 1 |
| Mirghani, H | 1 |
| Berdelou, A | 1 |
| Lumbroso, J | 1 |
| Deandreis, D | 1 |
| Baudin, E | 1 |
| Schlumberger, M | 1 |
| Laurent, S | 1 |
| Hee, HI | 1 |
| Goy, RW | 1 |
| Ng, AS | 1 |
| Eisenberg, E | 1 |
| Konopniki, M | 1 |
| Veitsman, E | 1 |
| Kramskay, R | 1 |
| Gaitini, D | 1 |
| Baruch, Y | 1 |
| Gerard, LL | 1 |
| Cooper, CS | 1 |
| Duethman, KS | 1 |
| Gordley, BM | 1 |
| Kleiber, CM | 1 |
| Soloway, MS | 1 |
| Adriansson, C | 1 |
| Suserud, BO | 1 |
| Bergbom, I | 1 |
| Tummon, I | 1 |
| Newton, C | 1 |
| Lee, C | 1 |
| Martin, J | 1 |
| Yiannakopoulos, CK | 1 |
| Kanellopoulos, AD | 1 |
| Wall, PM | 1 |
| Blanchard, RJ | 1 |
| Yang, M | 1 |
| Blanchard, DC | 1 |
| Zempsky, WT | 1 |
| Cravero, JP | 1 |
| Vase, L | 1 |
| Robinson, ME | 1 |
| Verne, NG | 1 |
| Price, DD | 1 |
| Ekbom, K | 1 |
| Jakobsson, J | 1 |
| Marcus, C | 1 |
| Batra, S | 1 |
| Sarasin, S | 1 |
| Bertoglio, LJ | 1 |
| Joca, SR | 1 |
| Guimarães, FS | 2 |
| Kleiber, C | 1 |
| Schutte, DL | 1 |
| McCarthy, AM | 1 |
| Floria-Santos, M | 1 |
| Murray, JC | 1 |
| Hanrahan, K | 1 |
| Akay, S | 1 |
| Karasu, Z | 1 |
| Noyan, A | 1 |
| Pala, S | 1 |
| Musoglu, A | 1 |
| Ilter, T | 1 |
| Batur, Y | 1 |
| Jonas, NE | 1 |
| Visser, MF | 1 |
| Oomen, A | 1 |
| Albertyn, R | 1 |
| van Dijk, M | 1 |
| Prescott, CA | 1 |
| Tekdogan, U | 1 |
| Nalcacioglu, V | 1 |
| Resstel, LB | 1 |
| Souza, RF | 1 |
| Koenig, J | 1 |
| Cosquer, B | 1 |
| Cassel, JC | 1 |
| Hilgart, L | 1 |
| Dry, J | 1 |
| Leynadier, F | 1 |
| Scudds, RA | 1 |
| Janzen, V | 1 |
| Delaney, G | 1 |
| Heck, C | 1 |
| McCain, GA | 1 |
| Russell, AL | 1 |
| Teasell, RW | 1 |
| Varkey, G | 1 |
| Woodbury, GM | 1 |
| Holmes, HS | 1 |
| Fatovich, DM | 1 |
| Jacobs, IG | 1 |
| Stein, M | 1 |
| Lubetkin, D | 1 |
| Taub, HC | 1 |
| Skinner, WK | 1 |
| Haberman, J | 1 |
| Kreutzer, ER | 1 |
| Sutherland, R | 1 |
| Vetter, TR | 1 |
| Tan, CC | 1 |
| Freeman, JG | 1 |
| Martin, JP | 1 |
| Arlett, PA | 1 |
| Holdstock, G | 1 |
| Holland, IS | 1 |
| Stassen, LF | 1 |
| Lander, J | 1 |
| Hodgins, M | 1 |
| Nazarali, S | 1 |
| McTavish, J | 1 |
| Ouellette, J | 1 |
| Friesen, E | 1 |
| Young, SS | 1 |
| Schwartz, R | 1 |
| Sheridan, MJ | 1 |
| Davies, SJ | 1 |
| Paech, MJ | 1 |
| Welch, H | 1 |
| Evans, SF | 1 |
| Pavy, TJ | 1 |
| Fein, JA | 1 |
| Boardman, CR | 1 |
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| Boezaart, AP | 1 |
| Berry, RA | 1 |
| Laubscher, JJ | 1 |
| Nell, ML | 1 |
| Mjahed, K | 1 |
| Sadraoui, A | 1 |
| Benslama, A | 1 |
| Idali, B | 1 |
| Benaguida, M | 1 |
| Mitchell, SJ | 1 |
| Pellett, O | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Use Of The Needle Free Jet-Injection System With Buffered Lidocaine (J-Tip) For The Treatment Of Pain During Venipuncture For Blood Draws In Young Children[NCT01890642] | 205 participants (Actual) | Interventional | 2013-07-31 | Completed | |||
| Lidocaine Administration During Flexible Bronchoscopy and Endobronchial Ultrasound[NCT03829618] | Phase 3 | 29 participants (Actual) | Interventional | 2019-04-01 | Terminated (stopped due to COVID lack of cases/recruitment) | ||
| Effectiveness of HYPNOsis Masks in the Management of Pain and Anxiety During Botulinum TOXin Injections in the Treatment of Idiopathic Overactive Bladder: a Multicenter Randomized Parallel Group Study.[NCT05352945] | 70 participants (Anticipated) | Interventional | 2022-06-30 | Not yet recruiting | |||
| The Effect of Watching Relaxing Video on Pain and Anxiety Levels of Female Patients During Cystoscopy: A Randomized Controlled Trial[NCT03865459] | 60 participants (Actual) | Interventional | 2017-12-01 | Completed | |||
| The Effects of Listening Music During Breathing Exercises on Vital Sings and Pulmonary Functions After Video-assisted Thoracoscopic Surgery:A Randomized-controlled Study[NCT05329519] | 30 participants (Actual) | Interventional | 2016-06-15 | Completed | |||
| Effectiveness of the Distraction Methods on Pain, Anxiety and Satisfaction During Cystoscopy[NCT02764294] | 120 participants (Actual) | Interventional | 2016-03-31 | Completed | |||
| The Effect of Music With Structured Verbal Training on Pain, Anxiety and Satisfaction During Prostate Biopsy[NCT04466202] | 100 participants (Actual) | Interventional | 2020-01-22 | Completed | |||
| The Postoperative Analgesic Effect of Dexamethasone Added to Topical Bupivacaine in Endoscopic Nasal Surgery[NCT03036605] | Phase 4 | 60 participants (Actual) | Interventional | 2017-03-15 | Completed | ||
| Efficacy of Treatments for Provoked Vestivulodynia : a Randomised Clinical Trial Comparing Multimodal Physiotherapy Treatments to Topical Lidocaine[NCT01455350] | 212 participants (Actual) | Interventional | 2011-10-31 | Completed | |||
| A Comparison of Lidocaine, Buffered Lidocaine, and Bacteriostatic Normal Saline for Local Anesthesia Prior to Peripheral Intravenous Catheterization[NCT01759459] | Phase 4 | 150 participants (Actual) | Interventional | 2013-01-31 | Completed | ||
| Intranasal Lidocaine to Treat Pediatric Migraine in the Emergency Department[NCT03576820] | Phase 3 | 50 participants (Anticipated) | Interventional | 2018-10-15 | Recruiting | ||
| Intranasal Sufentanil for Analgesia of Severe Sickle Cell Vaso-occlusive Pain Crisis in the Pediatric Emergency Department: a Double Blind Randomized Versus Placebo Controlled Trial[NCT06181695] | Phase 3 | 182 participants (Anticipated) | Interventional | 2024-05-02 | Not yet recruiting | ||
| Cognitive Changes Associated With Initiation of Gabapentin Treatment in Adults With Chronic Pain[NCT04106011] | 3 participants (Actual) | Observational | 2020-01-10 | Terminated (stopped due to PI request - low enrollment) | |||
| The Effect of Playing Games With Tablet on Pain and Anxiety During Circumcision in Children: A Randomized Controlled Study[NCT04220346] | 70 participants (Actual) | Interventional | 2018-10-01 | Completed | |||
| Comparison of Outcome of Post Burn Flexion Contracture Release Under Tourniquet Verses Tumescent Technique in Children[NCT02501720] | 80 participants (Anticipated) | Interventional | 2015-09-30 | Not yet recruiting | |||
| Efficacy of Inhaled 50% Equimolar Nitrous Oxide/Oxygen Gas Premix (Kalinox®) as Compared to Topically Administered 5% Eutectic Mixture of Lidocaine/Prilocaine (EMLA®) in Chronic Leg Ulcer Debridement[NCT02696460] | 21 participants (Actual) | Interventional | 2010-04-30 | Completed | |||
| 19-Gauge Fine Needle Aspirate (FNA) Versus 19-Gauge Fine Needle Biopsy (FNB) Needles for Endoscopic Ultrasound Guided Liver Biopsy (EUS-LB): A Randomized Prospective Trial[NCT03408171] | 40 participants (Actual) | Interventional | 2017-10-02 | Completed | |||
| 19 Versus 22-Gauge Fine Needle Biopsy (FNB) Needles for Endoscopic Ultrasound Guided Liver Biopsy (EUS-LB): A Prospective Pilot Study[NCT02967991] | 20 participants (Actual) | Interventional | 2016-08-31 | Completed | |||
| Comparison of Pain Scores Between Endoscopic Ultrasound (EUS)-Guided Liver Biopsy and Percutaneous Liver Biopsy[NCT02947516] | 0 participants (Actual) | Interventional | 2017-01-31 | Withdrawn (stopped due to Funding n/a) | |||
| Contribution of Hypnosis in Guided Hepatic Biopsy[NCT05413174] | 70 participants (Actual) | Interventional | 2022-09-29 | Completed | |||
| A Comparison of Amethocaine Creams Versus Liposomal Lidocaine Cream as Pain Reliever Prior to Venipuncture in Children at the Paediatric Emergency Department.[NCT00353002] | 0 participants (Actual) | Interventional | 2006-07-31 | Withdrawn | |||
| A Randomized, Placebo-Controlled Trial to Evaluate Pain and Anxiety During Venipuncture in Pediatric Patients With or Without Pre-treatment by a Topical Anesthetic[NCT00676364] | Phase 4 | 114 participants (Actual) | Interventional | 2003-03-31 | Completed | ||
| Randomized Controlled Trial of IN Midazolam vs IN Dexmedetomidine vs IN Ketamine Evaluating Length of Stay After Medication Administration and Anxiolysis During Minimal Procedures in Pediatric Population in Pediatric Emergency Department[NCT05934669] | Phase 4 | 90 participants (Anticipated) | Interventional | 2024-01-31 | Not yet recruiting | ||
| Prospective Comparison of Single vs. Staged Extractions: OHRQoL Outcomes for Wisdom Teeth Removal[NCT05820867] | 59 participants (Actual) | Interventional | 2018-03-01 | Completed | |||
| Topical Analgesia Before Inhalational Anaesthesia: A Retrospective Observational Study[NCT04959409] | 500 participants (Actual) | Observational | 2020-08-01 | Completed | |||
| Lidocaine For Neuroprotection During Cardiac Surgery[NCT00938964] | 550 participants (Actual) | Interventional | 2009-07-31 | Completed | |||
| Use of Handheld Audiovisual Devices to Treat Pediatric Preoperative Anxiety: A Randomized Control Trial.[NCT02286674] | 200 participants (Actual) | Interventional | 2014-11-30 | Completed | |||
| Effectivity of 0.5 mg/kg Propofol in the End of Anesthesia to Reduce the Incidence of Postanesthetic Emergence Agitation in Pediatric Patients Under General Inhalation Anesthesia[NCT03528954] | 54 participants (Actual) | Interventional | 2018-05-31 | Completed | |||
| Understanding Pediatric Symptoms and Other Symptoms[NCT00166231] | 156 participants (Actual) | Observational | 2004-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Pain score assessed by video reviewer before intervention (0 minute) and at venipuncture (3 minutes). The score at baseline was subtracted from the score at venipuncture to give a number indicating the change in pain scores.~The FLACC (Face, legs, activity, cry and consolability) Scale, ranging from 0 (no pain) to 10 (worst pain), was used to assess pain." (NCT01890642)
Timeframe: 3 min
| Intervention | units on a scale (Mean) |
|---|---|
| J Tip Noise | 2.32 |
| Pain Ease | 3.7 |
| J Tip | 1.58 |
"Pain score assessed by video reviewer at J-tip, J-tip noise or researcher approach (1 minute) and at venipuncture (3 minutes). The score at J-tip noise/researcher approach was subtracted from the score at venipuncture to give a number indicating the change in pain scores.~The FLACC (Face, legs, activity, cry and consolability) Scale, ranging from 0 (no pain) to 10 (worst pain), was used to assess pain." (NCT01890642)
Timeframe: 3 min
| Intervention | units on a scale (Mean) |
|---|---|
| J Tip Noise | 1.71 |
| Pain Ease | 2.82 |
| J Tip | 0.23 |
Proportion of patients where blood draw was successful on first attempt (NCT01890642)
Timeframe: up to 3 minutes
| Intervention | participants (Number) |
|---|---|
| J Tip Noise | 52 |
| Pain Ease | 48 |
| J Tip | 86 |
Pain when J-tip deployed assessed by video reviewers using pain scale. The FLACC (Face, legs, activity, cry and consolability) Scale, ranging from 0 (no pain) to 10 (worst pain), was used to assess pain. (NCT01890642)
Timeframe: 1 minute
| Intervention | units on a scale (Median) |
|---|---|
| J Tip Noise | 3.25 |
| Pain Ease | 2.5 |
| J Tip | 4.0 |
Pain score as assessed by video reviewers. The FLACC (Face, legs, activity, cry and consolability) Scale, ranging from 0 (no pain) to 10 (worst pain), was used to assess pain. (NCT01890642)
Timeframe: At venipuncture (3 minutes)
| Intervention | units on a scale (Median) |
|---|---|
| J Tip Noise | 5.75 |
| Pain Ease | 8 |
| J Tip | 5.25 |
Total alfentanyl dosing by anesthesia in mcg/kg (NCT03829618)
Timeframe: 1 day
| Intervention | mcg/kg (Mean) |
|---|---|
| Topical Lidocaine | 16.61 |
| Nebuliser Solution | 47.99 |
| Atomizer Solution | 4.40 |
time in minutes from scope out until ready for transport to post anesthesia care unit (NCT03829618)
Timeframe: 1 day
| Intervention | minutes (Mean) |
|---|---|
| Topical Lidocaine | 8.47 |
| Nebuliser Solution | 13.00 |
| Atomizer Solution | 6.14 |
Number of coughs during procedure as defined by cough requiring stopping procedure or treatment by anesthesiologist with propofol or alfentanyl (NCT03829618)
Timeframe: 1 day
| Intervention | coughs (Mean) |
|---|---|
| Topical Lidocaine | 1.20 |
| Nebuliser Solution | 1.71 |
| Atomizer Solution | 1.00 |
total fentanyl dosing by anesthesia in mcg/kg (NCT03829618)
Timeframe: 1 day
| Intervention | mcg/kg (Mean) |
|---|---|
| Topical Lidocaine | 0.30 |
| Nebuliser Solution | 0.24 |
| Atomizer Solution | 0.48 |
Total propofol dosing by anesthesia in mg/kg (NCT03829618)
Timeframe: 1 day
| Intervention | mg/kg (Mean) |
|---|---|
| Topical Lidocaine | 5.30 |
| Nebuliser Solution | 6.93 |
| Atomizer Solution | 3.26 |
A secondary outcome includes a pharmacoeconomic analysis that will look specifically at the cost-savings of using one agent over the other and will take into account the daily time allocated to pharmacy technicians and pharmacists for compounding and verifying buffered lidocaine. The outcome data was measured and reported in a single value dollar amount per group, tallied over a 3 month period. The dollar amounts were estimated by adding up the costs of drug purchasing, technician compounding time, and pharmacist verifying time. Buffered lidocaine required both drug purchasing and compounding time, where the lidocaine and bacteriostatic normal saline required drug purchasing alone and labor costs were not taken into account. (NCT01759459)
Timeframe: 3 months
| Intervention | Dollars (Number) |
|---|---|
| Buffered Lidocaine Cost | 13400 |
| Lidocaine Cost | 9100 |
| Bacteriostatic Normal Saline Cost | 4840 |
The primary outcome measured in this study will be the level of pain reported, on a scale of 0 to 10, 0 being no pain at all and 10 being the worst pain ever felt, by the patient upon administration of the local anesthetic and upon insertion of the peripheral intravenous catheter. (NCT01759459)
Timeframe: Day 1
| Intervention | units on a scale (Mean) |
|---|---|
| Lidocaine | 2.81 |
| Buffered Lidocaine | 1.64 |
| Bacteriostatic Normal Saline | 2.05 |
The primary outcome measured in this study will be the level of pain reported, on a scale of 0 to 10, 0 being no pain at all and 10 being the worst pain ever felt, by the patient upon administration of the local anesthetic and upon insertion of the peripheral intravenous catheter. (NCT01759459)
Timeframe: Baseline and day 1
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Average pain score following medication injection | Average pain score following IV inserti | |
| Bacteriostatic Normal Saline | 2.10 | 3.05 |
| Buffered Lidocaine | 1.6 | 1.81 |
| Lidocaine | 2.58 | 1.81 |
(NCT03408171)
Timeframe: Number Analyzed
| Intervention | mm (Median) |
|---|---|
| 19-gauge FNA Needle | 32.3 |
| 19-gauge FNB Needle | 30.2 |
Number of portal triads (PT) in the specimen. (NCT03408171)
Timeframe: 3-5 days
| Intervention | Portal Triads (Mean) |
|---|---|
| 19-gauge FNA Needle | 18.1 |
| 19-gauge FNB Needle | 42.6 |
Number of portal triads (PT) in the specimen. (NCT03408171)
Timeframe: 3-5 days
| Intervention | Complete number of portal triads (Median) |
|---|---|
| 19-gauge FNA Needle | 16.5 |
| 19-gauge FNB Needle | 38 |
Post-processing Aggregate specimen length (ASL) measured in centimeter (NCT03408171)
Timeframe: 3-5 days
| Intervention | centimeter (Mean) |
|---|---|
| 19-gauge FNA Needle | 11.4 |
| 19-gauge FNB Needle | 15.32 |
Post-processing Length of the longest piece (LLP) measured in centimeter (NCT03408171)
Timeframe: 3-5 days
| Intervention | centimeter (Mean) |
|---|---|
| 19-gauge FNA Needle | 1.05 |
| 19-gauge FNB Needle | 1.78 |
Pre-processing Aggregate specimen length (ASL) measured in centimeter (NCT03408171)
Timeframe: 3-5 days
| Intervention | centimeter (Mean) |
|---|---|
| 19-gauge FNA Needle | 10.89 |
| 19-gauge FNB Needle | 15.78 |
Pre-processing Length of the longest piece (LLP) measured in centimeter (NCT03408171)
Timeframe: up to 5 days
| Intervention | centimeter (Mean) |
|---|---|
| 19-gauge FNA Needle | 1.47 |
| 19-gauge FNB Needle | 2.09 |
Number of cases for which a histologic diagnosis could be made based upon the amount of tissue obtained with the needle. (NCT03408171)
Timeframe: 3-5 days
| Intervention | Participants (Count of Participants) |
|---|---|
| 19-gauge FNA Needle | 20 |
| 19-gauge FNB Needle | 20 |
No. of fragments > 9 mm, mean (SD) Pre-processing Post-processing (NCT03408171)
Timeframe: 3-5 days
| Intervention | Number of Fragments (Mean) | |
|---|---|---|
| Pre-processing | Post-processing | |
| 19-gauge FNA Needle | 3.5 | 1.1 |
| 19-gauge FNB Needle | 7.7 | 4.8 |
"Length of all the tissue (centimeters) by adding the sum of all pieces Subjects underwent a left liver biopsy using a 19-gauge FNA needle, 22-gauge FNB needle, right liver biopsies also using the 19-gauge FNA and 22-gauge FNB.~FNA-fine needle aspiration FNB-fine needle biopsy" (NCT02967991)
Timeframe: 7 days
| Intervention | cm for portal tracts of specimens (Mean) |
|---|---|
| 19 Gauge FNA | 76.5 |
| 22 Gauge FNB | 66.9 |
"length of the longest tissue biopsy piece (centimeters) as measured by pathology Subjects underwent a left liver biopsy using a 19-gauge FNA needle, 22-gauge FNB needle, right liver biopsies also using the 19-gauge FNA and 22-gauge FNB.~FNA-fine needle aspiration FNB-fine needle biopsy" (NCT02967991)
Timeframe: 7 days
| Intervention | mean cm for portal tracts of specimens (Mean) |
|---|---|
| 19 Gauge FNA | 13.2 |
| 22 Gauge FNB | 10.8 |
"Number of portal tracts (PT) in the specimen (total) under histologic examination Subjects underwent a left liver biopsy using a 19-gauge FNA needle, 22-gauge FNB needle, right liver biopsies also using the 19-gauge FNA and 22-gauge FNB.~FNA-fine needle aspiration FNB-fine needle biopsy" (NCT02967991)
Timeframe: 7 days
| Intervention | mean portal tracts (Mean) |
|---|---|
| 19 Gauge FNA | 7.4 |
| 22 Gauge FNB | 6.1 |
"Defined by total portal structures > 5 or length of the longest piece > 15 mm) Subjects underwent a left liver biopsy using a 19-gauge FNA needle, 22-gauge FNB needle, right liver biopsies also using the 19-gauge FNA and 22-gauge FNB.~FNA-fine needle aspiration FNB-fine needle biopsy" (NCT02967991)
Timeframe: 7 days
| Intervention | specimens (Number) |
|---|---|
| 19 Gauge FNA | 17 |
| 22 Gauge FNB | 14 |
"Patient requiring visit to healthcare center (emergency room, hospital, call to service) within time 7 days Subjects underwent a left liver biopsy using a 19-gauge FNA needle, 22-gauge FNB needle, right liver biopsies also using the 19-gauge FNA and 22-gauge FNB.~FNA-fine needle aspiration FNB-fine needle biopsy" (NCT02967991)
Timeframe: 7 Days
| Intervention | Participants (Count of Participants) |
|---|---|
| Total Population | 1 |
"Pain using Likert score 0-10 (10 worst) Subjects underwent a left liver biopsy using a 19-gauge FNA needle, 22-gauge FNB needle, right liver biopsies also using the 19-gauge FNA and 22-gauge FNB.~FNA-fine needle aspiration FNB-fine needle biopsy" (NCT02967991)
Timeframe: 1 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Total Population | 0 |
"Pain using Likert score 0-10 (10 worst) Subjects underwent a left liver biopsy using a 19-gauge FNA needle, 22-gauge FNB needle, right liver biopsies also using the 19-gauge FNA and 22-gauge FNB.~FNA-fine needle aspiration FNB-fine needle biopsy" (NCT02967991)
Timeframe: 7 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Total Population | 1 |
"Patient with blood visible from patient's mouth, rectum with a 2 gram drop in hemoglobin Subjects underwent a left liver biopsy using a 19-gauge FNA needle, 22-gauge FNB needle, right liver biopsies also using the 19-gauge FNA and 22-gauge FNB.~FNA-fine needle aspiration FNB-fine needle biopsy" (NCT02967991)
Timeframe: 7 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Total Population | 0 |
"Presence of visible clots in specimen (yes/no) Subjects underwent a left liver biopsy using a 19-gauge FNA needle, 22-gauge FNB needle, right liver biopsies also using the 19-gauge FNA and 22-gauge FNB.~FNA-fine needle aspiration FNB-fine needle biopsy" (NCT02967991)
Timeframe: Day of Procedure
| Intervention | specimens (Number) |
|---|---|
| 19 Gauge FNA | 4 |
| 22 Gauge FNB | 1 |
"Presence of a visible core specimen (yes/no) Subjects underwent a left liver biopsy using a 19-gauge FNA needle, 22-gauge FNB needle, right liver biopsies also using the 19-gauge FNA and 22-gauge FNB.~FNA-fine needle aspiration FNB-fine needle biopsy" (NCT02967991)
Timeframe: Day of Procedure
| Intervention | specimens (Number) |
|---|---|
| 19 Gauge FNA | 20 |
| 22 Gauge FNB | 19 |
Participant anxiety was measured by the study participant and the objective observer before (anticipatory), during (venipuncture) and after (recovery) venipuncture using a validated visual analog scale (VAS). The VAS is a validated scale that is used to detect small changes in many types of observations. The scale ranges from 0-100 scores on a scale, and here the higher scores indicate higher anxiety levels. Only the participant's mean venipuncture (during venipuncture) anxiety scores are presented in outcome measure results here. (NCT00676364)
Timeframe: During venipuncture
| Intervention | scores on a scale (Mean) |
|---|---|
| ControI Group Receiving Placebo Cream | 43.1 |
| Investigational Group | 40.5 |
"Pain was measured immediately after venipuncture by the participant using the six-point FACES scale. FACES in not an acronym, but rather a description of a pain scale that uses pictures of faces in various states of pain. The FACES pain scale is a common scale used to measure pain with scores on a scale. The scale we used had six points from zero (0) to five (5) indicating different levels of pain. Lower scores indicate lower levels of pain, and higher scores indicate higher levels of pain." (NCT00676364)
Timeframe: Pain was measured immediately after venipuncture.
| Intervention | scores on a scale (Mean) |
|---|---|
| ControI Group Receiving Placebo Cream | 2.2 |
| Investigational Group Receiving 4% Lidocaine Cream | 2.1 |
"Center for Epidemiological Studies Depression Scale (CES-D). The CES-D is a 20-item self-report examination designed to measure symptoms of depression. Subjects rate the degree to which they have experienced a range of symptoms of depression, such as I had crying spells and I felt lonely. Scores range from 0 to 60, with higher scores indicating greater depressive symptoms. Scores greater than 16 are typically considered indicative of clinically significant depression." (NCT00938964)
Timeframe: baseline, 1-year
| Intervention | units on a scale (Mean) |
|---|---|
| Lidocaine | -1.27 |
| Placebo | -0.89 |
"Center for Epidemiological Studies Depression Scale (CES-D). The CES-D is a 20-item self-report examination designed to measure symptoms of depression. Subjects rate the degree to which they have experienced a range of symptoms of depression, such as I had crying spells and I felt lonely. Scores range from 0 to 60, with higher scores indicating greater depressive symptoms. Scores greater than 16 are typically considered indicative of clinically significant depression." (NCT00938964)
Timeframe: baseline, 6-weeks
| Intervention | units on a scale (Mean) |
|---|---|
| Lidocaine | 0.57 |
| Placebo | 0.16 |
To characterize cognitive function over time, while minimizing potential redundancy in the cognitive measures, a factor analysis was performed on the 14 cognitive test scores from baseline. We chose a five-factor solution, which represents 5 cognitive domains: structured verbal memory, unstructured verbal memory, executive function, visual memory and attention/concentration. To quantify overall cognitive function, a baseline cognitive index was first calculated as the mean of the 5 preoperative domain scores. The cognitive index score has a mean of zero, thus any positive score is above the mean, any negative score is below the mean. A continuous change score was then calculated by subtracting the baseline from the 1 year cognitive index. The resulting outcome measure is unbounded with standard deviation of 0.35. A negative change score indicating decline and a positive score indicating improvement (NCT00938964)
Timeframe: 1 year after surgery
| Intervention | units on a scale (Mean) |
|---|---|
| Lidocaine | 0.09 |
| Placebo | 0.07 |
To characterize cognitive function over time, while minimizing potential redundancy in the cognitive measures, a factor analysis was performed on the 14 cognitive test scores from baseline. We chose a five-factor solution, which represents 5 cognitive domains: structured verbal memory, unstructured verbal memory, executive function, visual memory and attention/concentration. To quantify overall cognitive function, a baseline cognitive index was first calculated as the mean of the 5 preoperative domain scores. The cognitive index score has a mean of zero, thus any positive score is above the mean, any negative score is below the mean. A continuous change score was then calculated by subtracting the baseline from the 6-week cognitive index. The resulting outcome measure is unbounded with standard deviation of 0.35. A negative change score indicating decline and a positive score indicating improvement. (NCT00938964)
Timeframe: Preoperative to 6 weeks after surgery
| Intervention | units on a scale (Mean) |
|---|---|
| Lidocaine | 0.07 |
| Placebo | 0.07 |
"The DASI is a 12-item scale of functional capacity that has been found to correlate well with objective measures of maximal exercise capacity. Items reflect activities of personal care, ambulation, household tasks, sexual function, and recreational activities. Activities done with no difficulty receive scores, which are weighted and summed, for a quantitative measure of functional status. Scores range from 0 to 60; a higher-weighted score indicates better function." (NCT00938964)
Timeframe: baseline, 1-year
| Intervention | units on a scale (Mean) |
|---|---|
| Lidocaine | 6.3 |
| Placebo | 6.96 |
"The DASI is a 12-item scale of functional capacity that has been found to correlate well with objective measures of maximal exercise capacity. Items reflect activities of personal care, ambulation, household tasks, sexual function, and recreational activities. Activities done with no difficulty receive scores, which are weighted and summed, for a quantitative measure of functional status. Scores range from 0 to 60; a higher-weighted score indicates better function." (NCT00938964)
Timeframe: baseline, 6-weeks
| Intervention | units on a scale (Mean) |
|---|---|
| Lidocaine | -10.98 |
| Placebo | -11.67 |
The National Institutes of Health Stroke Scale (NIHSS) is a 15-item neurologic examination stroke scale used to evaluate the effect of acute cerebral infarction on the levels of consciousness, language, neglect, visual-field loss, extraocular movement, motor strength, ataxia, dysarthria, and sensory loss. A trained observer rates the patent's ability to answer questions and perform activities. Ratings for each item are scored with 3 to 5 grades with 0 as normal, and there is an allowance for untestable items. The range of scores is from 0 (normal) to 42 (profound effect of stroke on patient). (NCT00938964)
Timeframe: baseline, 1-year
| Intervention | units on a scale (Mean) |
|---|---|
| Lidocaine | 0.05 |
| Placebo | 0.07 |
The National Institutes of Health Stroke Scale (NIHSS) is a 15-item neurologic examination stroke scale used to evaluate the effect of acute cerebral infarction on the levels of consciousness, language, neglect, visual-field loss, extraocular movement, motor strength, ataxia, dysarthria, and sensory loss. A trained observer rates the patent's ability to answer questions and perform activities. Ratings for each item are scored with 3 to 5 grades with 0 as normal, and there is an allowance for untestable items. The range of scores is from 0 (normal) to 42 (profound effect of stroke on patient). (NCT00938964)
Timeframe: baseline, 6-weeks
| Intervention | units on a scale (Mean) |
|---|---|
| Lidocaine | 0.05 |
| Placebo | 0.04 |
The Western perioperative neurologic scale was designed to detect neurologic deficits after cardiac surgery. It includes 14 items classified into eight domains (mentation, speech, cranial nerve function, motor weakness, sensation and cerebellum, reflexes, and gait). Each item is scored from 0 (severe deficit) to3 (normal), and a maximum score of 42 indicates normal neurological function. (NCT00938964)
Timeframe: baseline, 1-year
| Intervention | units on a scale (Mean) |
|---|---|
| Lidocaine | 0.02 |
| Placebo | -0.02 |
The Western perioperative neurologic scale was designed to detect neurologic deficits after cardiac surgery. It includes 14 items classified into eight domains (mentation, speech, cranial nerve function, motor weakness, sensation and cerebellum, reflexes, and gait). Each item is scored from 0 (severe deficit) to3 (normal), and a maximum score of 42 indicates normal neurological function. (NCT00938964)
Timeframe: baseline, 6-weeks
| Intervention | units on a scale (Mean) |
|---|---|
| Lidocaine | 0.04 |
| Placebo | -0.01 |
"Perceived Social Support Scale: Twelve items indicate how strongly subjects agree that there is a special person who is around when I am in need and my family really tries to help me. Choices range from very strongly disagree to very strongly agree. Items are summed for a range of 12 to 84, with a high score meaning more social support." (NCT00938964)
Timeframe: baseline, 1-year
| Intervention | units on a scale (Mean) |
|---|---|
| Lidocaine | 0.71 |
| Placebo | -1.16 |
"Perceived Social Support Scale: Twelve items indicate how strongly subjects agree that there is a special person who is around when I am in need and my family really tries to help me. Choices range from very strongly disagree to very strongly agree. Items are summed for a range of 12 to 84, with a high score meaning more social support." (NCT00938964)
Timeframe: baseline, 6-weeks
| Intervention | units on a scale (Mean) |
|---|---|
| Lidocaine | 1.23 |
| Placebo | -0.49 |
"Social Activity: This measure consisted of eight items that indicate the degree of social interaction. Sample items are How often do you talk on the telephone with friends and relatives? and How often do you attend meetings of social groups, clubs, or civic organizations? Scores range from 8 to 32. A lower score indicates more social activity." (NCT00938964)
Timeframe: baseline, 1-year
| Intervention | units on a scale (Mean) |
|---|---|
| Lidocaine | -0.20 |
| Placebo | 0.03 |
"Social Activity: This measure consisted of eight items that indicate the degree of social interaction. Sample items are How often do you talk on the telephone with friends and relatives? and How often do you attend meetings of social groups, clubs, or civic organizations? Scores range from 8 to 32. A lower score indicates more social activity." (NCT00938964)
Timeframe: baseline, 6-weeks
| Intervention | units on a scale (Mean) |
|---|---|
| Lidocaine | 0.95 |
| Placebo | 1.59 |
"Spielberger State Anxiety Inventory (STAI): The STAI consists of two 20-item scales that measure anxiety. Representative items include statements such as I feel nervous and I feel worried. These items are rated on a 4-point scale, based on how well they describe the patient's current or typical mood, from not at all to very much so. Scores range from 20 to 80, with higher scores indicating greater anxiety." (NCT00938964)
Timeframe: baseline, 1-year
| Intervention | units on a scale (Mean) |
|---|---|
| Lidocaine | -6.70 |
| Placebo | -6.39 |
"Spielberger State Anxiety Inventory (STAI): The STAI consists of two 20-item scales that measure anxiety. Representative items include statements such as I feel nervous and I feel worried. These items are rated on a 4-point scale, based on how well they describe the patient's current or typical mood, from not at all to very much so. Scores range from 20 to 80, with higher scores indicating greater anxiety." (NCT00938964)
Timeframe: baseline, 6-weeks
| Intervention | units on a scale (Mean) |
|---|---|
| Lidocaine | -7.12 |
| Placebo | -6.31 |
Symptom limitations: Patients were given a list of eight symptoms and asked to rate the degree to which the symptom limited daily activities. The symptoms were angina, shortness of breath, arthritis, back trouble, leg pains, headaches, fatigue, and other. Scores range from 8 to 32, with higher scores indicating greater limitations. (NCT00938964)
Timeframe: baseline, 1-year
| Intervention | units on a scale (Mean) |
|---|---|
| Lidocaine | -1.39 |
| Placebo | -1.48 |
Symptom limitations: Patients were given a list of eight symptoms and asked to rate the degree to which the symptom limited daily activities. The symptoms were angina, shortness of breath, arthritis, back trouble, leg pains, headaches, fatigue, and other. Scores range from 8 to 32, with higher scores indicating greater limitations. (NCT00938964)
Timeframe: baseline, 6-weeks
| Intervention | units on a scale (Mean) |
|---|---|
| Lidocaine | -0.67 |
| Placebo | -0.8 |
"Cognitive Difficulties Scale: a 39-item scale, is a self-report assessment of perceived problems in long- and short-term memory, concentration, attention, and psycho-motor coordination. Sample items are I forget errands I planned to do and I fail to recognize people I know. Scores range from 39 to 164, with higher scores indicating greater cognitive difficulty." (NCT00938964)
Timeframe: baseline, 1-year
| Intervention | units on a scale (Mean) |
|---|---|
| Lidocaine | -0.46 |
| Placebo | -1.02 |
"Cognitive Difficulties Scale: a 39-item scale, is a self-report assessment of perceived problems in long- and short-term memory, concentration, attention, and psycho-motor coordination. Sample items are I forget errands I planned to do and I fail to recognize people I know. Scores range from 39 to 164, with higher scores indicating greater cognitive difficulty." (NCT00938964)
Timeframe: baseline, 6-weeks
| Intervention | units on a scale (Mean) |
|---|---|
| Lidocaine | -3 |
| Placebo | -3.21 |
"Duke Older Americans Resources and Services Procedures- Instrumental Activities of Daily Living (OARS-IADL): This measure contains six items that assess the ability to perform important tasks for daily living (e.g., Could you prepare your own meals? Could you drive a car?). Scores range from 6 to 24. Higher scores indicate increasing difficulty in engaging in daily activities." (NCT00938964)
Timeframe: baseline, 1-year
| Intervention | units on a scale (Mean) |
|---|---|
| Lidocaine | -0.15 |
| Placebo | -0.31 |
"Duke Older Americans Resources and Services Procedures- Instrumental Activities of Daily Living (OARS-IADL): This measure contains six items that assess the ability to perform important tasks for daily living (e.g., Could you prepare your own meals? Could you drive a car?). Scores range from 6 to 24. Higher scores indicate increasing difficulty in engaging in daily activities." (NCT00938964)
Timeframe: baseline, 6-weeks
| Intervention | units on a scale (Mean) |
|---|---|
| Lidocaine | 2.46 |
| Placebo | 2.1 |
To characterize cognitive function over time, while minimizing potential redundancy in the cognitive measures, a factor analysis was performed on the 14 cognitive test scores from baseline. We chose a five-factor solution, which represents 5 cognitive domains: structured verbal memory, unstructured verbal memory, executive function, visual memory and attention/concentration. Each domain score is normally distributed with a mean of zero. A change score was calculated for each domain by subtracting the baseline from the 6-week score. A dichotomous outcome variable of post-operative cognitive deficit was defined as a decline of ≥1 standard deviation in 1 or more of the 5 domains. (NCT00938964)
Timeframe: Preoperative to 6 weeks after surgery
| Intervention | Participants (Count of Participants) |
|---|---|
| Lidocaine | 87 |
| Placebo | 83 |
The Medical Outcomes Study 36-Item Short Form Health Survey (SF-36): The SF-36 was designed to measure general health status. Two scales were used: Work Activities (four items) and General Health (one item). For the work activities scale, the reported score was the sum of four questions, each with values ranging from 1 to 4, the total score could range from 4 to 16. A higher score on Work Activities indicates more health-related problems For the general health question, the patients ranked their health from Excellent (1) to poor (5), the scale ranged from 1 to 5 with 1 being best health and 5 being worst. A high score in General Health indicates poorer health state. (NCT00938964)
Timeframe: baseline, 1-year
| Intervention | units on a scale (Mean) | |
|---|---|---|
| 1 year Change Work Activities | 1 year Change General health perception | |
| Lidocaine | -1.37 | -0.28 |
| Placebo | -1.42 | -0.43 |
The Medical Outcomes Study 36-Item Short Form Health Survey (SF-36): The SF-36 was designed to measure general health status. Two scales were used: Work Activities (four items) and General Health (one item). For the work activities scale, the reported score was the sum of four questions, each with values ranging from 1 to 4, the total score could range from 4 to 16. A higher score on Work Activities indicates more health-related problems For the general health question, the patients ranked their health from Excellent (1) to poor (5), the scale ranged from 1 to 5 with 1 being best health and 5 being worst. A high score in General Health indicates poorer health state. (NCT00938964)
Timeframe: baseline, 6-weeks
| Intervention | units on a scale (Mean) | |
|---|---|---|
| 6-Week Change Work activities | 6-Week Change General health perception | |
| Lidocaine | 2.71 | -0.004 |
| Placebo | 3 | -0.03 |
Paired jugular venous and radial arterial blood samples were drawn at baseline, cross-clamp removal, end of cardiopulmonary bypass, and 6 hours post cross-clamp removalime points and analyzed by fluorescence-activated cell sorting to identify activated platelets. Transcerebral activation gradients were calculated by subtracting arterial values from venous values and were compared between groups (NCT00938964)
Timeframe: Baseline to 6 hours post cross-clamp removal
| Intervention | Mean linear fluorescence intensity-MLFI (Mean) | |||
|---|---|---|---|---|
| Baseline | Cross-clamp removal | End of Bypass | 6 hours post cross-clamp removal | |
| Lidocaine | -0.15 | 0.02 | -0.73 | -0.10 |
| Placebo | -0.43 | -0.73 | -0.40 | 0.19 |
Paired jugular venous and radial arterial blood samples were drawn at baseline, cross-clamp removal, end of cardiopulmonary bypass, and 6 hours post cross-clamp removalime points and analyzed by fluorescence-activated cell sorting to identify activated platelets. Transcerebral activation gradients were calculated by subtracting arterial values from venous values and were compared between groups (NCT00938964)
Timeframe: Baseline to 6 hours post cross-clamp removal
| Intervention | Mean linear fluorescence intensity-MLFI (Mean) | |||
|---|---|---|---|---|
| Baseline | Cross-clamp removal | End of Bypass | 6 hours post cross-clamp removal | |
| Lidocaine | -4.22 | -2.46 | -0.34 | 1.21 |
| Placebo | -0.04 | 1.83 | 2.64 | 0.54 |
Paired jugular venous and radial arterial blood samples were drawn at baseline, cross-clamp removal, end of cardiopulmonary bypass, and 6 hours post cross-clamp removal and analyzed by fluorescence-activated cell sorting to identify activated platelets. Transcerebral activation gradients were calculated by subtracting arterial values from venous values and were compared between groups (NCT00938964)
Timeframe: Baseline to 6 hours post cross-clamp removal
| Intervention | Mean linear fluorescence intensity-MLFI (Mean) | |||
|---|---|---|---|---|
| Baseline | Cross-clamp removal | End of Bypass | 6 hours post cross-clamp removal | |
| Lidocaine | -2.02 | 0.56 | 0.58 | 1.04 |
| Placebo | -0.08 | 0.17 | 1.19 | -0.68 |
Paired jugular venous and radial arterial blood samples were drawn at baseline, cross-clamp removal, end of cardiopulmonary bypass, and 6 hours post cross-clamp removalime points and analyzed by fluorescence-activated cell sorting to identify activated platelets. Transcerebral activation gradients were calculated by subtracting arterial values from venous values and were compared between groups (NCT00938964)
Timeframe: Baseline to 6 hours post cross-clamp removal
| Intervention | Mean linear fluorescence intensity-MLFI (Mean) | |||
|---|---|---|---|---|
| Baseline | Cross-clamp removal | End of Bypass | 6 hours post cross-clamp removal | |
| Lidocaine | -0.03 | 0.03 | 0.33 | 0.37 |
| Placebo | 0.35 | 0.43 | 0.05 | 0.27 |
2 reviews available for lidocaine and Anxiety
| Article | Year |
|---|---|
Do Computerized Delivery Systems Promote Less Pain and Anxiety Compared to Traditional Local Anesthesia in Dental Procedures? A Systematic Review of the Literature.
Topics: Adult; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Anxiety; Carticaine; Humans; Lidoc | 2022 |
Choosing a local anesthetic.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Anxiety; Child; Humans; Injections, Intradermal; Lidoc | 1994 |
46 trials available for lidocaine and Anxiety
| Article | Year |
|---|---|
An Evaluation of High Preprocedural Anxiety and Venipuncture Pain Experienced by Young Children.
Topics: Anesthetics, Local; Anxiety; Child; Child, Preschool; Humans; Lidocaine; Male; Pain; Pain Measuremen | 2021 |
Evaluation of Hydrocodone/Acetaminophen for Pediatric Laceration Repair: A Randomized Trial.
Topics: Acetaminophen; Administration, Topical; Adolescent; Age Factors; Anxiety; Child; Child, Preschool; D | 2020 |
Cognitive-behavioral couple therapy versus lidocaine for provoked vestibulodynia: A randomized clinical trial.
Topics: Adult; Anxiety; Catastrophization; Cognitive Behavioral Therapy; Couples Therapy; Female; Humans; In | 2021 |
The Effect of Dextromethorphan Premedication on Cough and Patient Tolerance During Flexible Bronchoscopy: A Randomized, Double-blind, Placebo-controlled Trial.
Topics: Analgesics; Anesthetics, Local; Anti-Anxiety Agents; Antitussive Agents; Anxiety; Bronchoscopy; Coug | 2017 |
The Analgesic and Emotional Response to Intravenous Lidocaine Infusion in the Treatment of Postherpetic Neuralgia: A Randomized, Double-Blinded, Placebo-controlled Study.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anxiety; Depression; Double-Blind Method; Emotio | 2018 |
Efficacy of local lidocaine application on anxiety and depression and its curative effect on patients with chronic tension-type headache.
Topics: Adult; Anesthetics, Local; Anxiety; Depression; Double-Blind Method; Female; Humans; Injections; Lid | 2013 |
Music reduces panic: an initial study of listening to preferred music improves male patient discomfort and anxiety during flexible cystoscopy.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anxiety; Cystoscopy; Heart Rate; Humans; Lidocai | 2014 |
Music reduces panic: an initial study of listening to preferred music improves male patient discomfort and anxiety during flexible cystoscopy.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anxiety; Cystoscopy; Heart Rate; Humans; Lidocai | 2014 |
Music reduces panic: an initial study of listening to preferred music improves male patient discomfort and anxiety during flexible cystoscopy.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anxiety; Cystoscopy; Heart Rate; Humans; Lidocai | 2014 |
Music reduces panic: an initial study of listening to preferred music improves male patient discomfort and anxiety during flexible cystoscopy.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anxiety; Cystoscopy; Heart Rate; Humans; Lidocai | 2014 |
Music reduces panic: an initial study of listening to preferred music improves male patient discomfort and anxiety during flexible cystoscopy.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anxiety; Cystoscopy; Heart Rate; Humans; Lidocai | 2014 |
Music reduces panic: an initial study of listening to preferred music improves male patient discomfort and anxiety during flexible cystoscopy.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anxiety; Cystoscopy; Heart Rate; Humans; Lidocai | 2014 |
Music reduces panic: an initial study of listening to preferred music improves male patient discomfort and anxiety during flexible cystoscopy.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anxiety; Cystoscopy; Heart Rate; Humans; Lidocai | 2014 |
Music reduces panic: an initial study of listening to preferred music improves male patient discomfort and anxiety during flexible cystoscopy.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anxiety; Cystoscopy; Heart Rate; Humans; Lidocai | 2014 |
Music reduces panic: an initial study of listening to preferred music improves male patient discomfort and anxiety during flexible cystoscopy.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anxiety; Cystoscopy; Heart Rate; Humans; Lidocai | 2014 |
Music reduces panic: an initial study of listening to preferred music improves male patient discomfort and anxiety during flexible cystoscopy.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anxiety; Cystoscopy; Heart Rate; Humans; Lidocai | 2014 |
Music reduces panic: an initial study of listening to preferred music improves male patient discomfort and anxiety during flexible cystoscopy.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anxiety; Cystoscopy; Heart Rate; Humans; Lidocai | 2014 |
Music reduces panic: an initial study of listening to preferred music improves male patient discomfort and anxiety during flexible cystoscopy.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anxiety; Cystoscopy; Heart Rate; Humans; Lidocai | 2014 |
Music reduces panic: an initial study of listening to preferred music improves male patient discomfort and anxiety during flexible cystoscopy.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anxiety; Cystoscopy; Heart Rate; Humans; Lidocai | 2014 |
Music reduces panic: an initial study of listening to preferred music improves male patient discomfort and anxiety during flexible cystoscopy.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anxiety; Cystoscopy; Heart Rate; Humans; Lidocai | 2014 |
Music reduces panic: an initial study of listening to preferred music improves male patient discomfort and anxiety during flexible cystoscopy.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anxiety; Cystoscopy; Heart Rate; Humans; Lidocai | 2014 |
Music reduces panic: an initial study of listening to preferred music improves male patient discomfort and anxiety during flexible cystoscopy.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anxiety; Cystoscopy; Heart Rate; Humans; Lidocai | 2014 |
Listening to music during transrectal ultrasound-guided prostate biopsy decreases anxiety, pain and dissatisfaction in patients: a pilot randomized controlled trial.
Topics: Aged; Anxiety; Biopsy; Biopsy, Needle; Humans; Lidocaine; Male; Middle Aged; Music; Pain; Pain Measu | 2015 |
Local anesthesia with epinephrine is safe and effective for oral surgery in patients with type 2 diabetes mellitus and coronary disease: a prospective randomized study.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Anxiety; Blood Glucose; Blood | 2015 |
Effect on patient anxiety of lidocaine infiltration into nasal packing after septoplasty: prospective, controlled study.
Topics: Administration, Intranasal; Adult; Anxiety; Female; Humans; Lidocaine; Male; Middle Aged; Nasal Sept | 2015 |
Randomized clinical trial of multimodal physiotherapy treatment compared to overnight lidocaine ointment in women with provoked vestibulodynia: Design and methods.
Topics: Academic Medical Centers; Administration, Topical; Adult; Anesthetics, Local; Anxiety; Catastrophiza | 2016 |
Study of ideal topical pharyngeal anesthesia in upper gastrointestinal system endoscopy: A double-blind, randomized, controlled trial.
Topics: Adult; Anesthetics, Combined; Anesthetics, Local; Anxiety; Cough; Double-Blind Method; Endoscopy, Ga | 2016 |
Comparing the effectiveness of vapocoolant spray and lidocaine/procaine cream in reducing pain of intravenous cannulation: A randomized clinical trial.
Topics: Administration, Topical; Aerosols; Anesthetics, Local; Anxiety; Catheterization, Peripheral; Child; | 2017 |
A randomized, crossover comparison of injected buffered lidocaine, lidocaine cream, and no analgesia for peripheral intravenous cannula insertion.
Topics: Administration, Topical; Adult; Anesthetics, Local; Anxiety; Catheterization, Peripheral; Cross-Over | 2009 |
Comparison of articaine and lidocaine for infiltration anaesthesia in patients undergoing bone marrow aspiration and biopsy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Anxiety; Biopsy, | 2010 |
Improved ejaculatory latency, control and sexual satisfaction when PSD502 is applied topically in men with premature ejaculation: results of a phase III, double-blind, placebo-controlled study.
Topics: Administration, Topical; Adolescent; Adult; Aged; Anesthetics, Local; Anxiety; Coitus; Double-Blind | 2010 |
Intranasal lidocaine and midazolam for procedural sedation in children.
Topics: Administration, Intranasal; Anesthetics, Local; Anxiety; Child, Preschool; Conscious Sedation; Diagn | 2011 |
Intranasal lidocaine and midazolam for procedural sedation in children.
Topics: Administration, Intranasal; Anesthetics, Local; Anxiety; Child, Preschool; Conscious Sedation; Diagn | 2011 |
Intranasal lidocaine and midazolam for procedural sedation in children.
Topics: Administration, Intranasal; Anesthetics, Local; Anxiety; Child, Preschool; Conscious Sedation; Diagn | 2011 |
Intranasal lidocaine and midazolam for procedural sedation in children.
Topics: Administration, Intranasal; Anesthetics, Local; Anxiety; Child, Preschool; Conscious Sedation; Diagn | 2011 |
Adjuvant use of intravenous lidocaine for procedural burn pain relief: a randomized double-blind, placebo-controlled, cross-over trial.
Topics: Adolescent; Adult; Aged; Analgesia; Analgesics, Opioid; Anxiety; Burns; Cross-Over Studies; Double-B | 2011 |
No effect of perianal application of topical anaesthetic on patient comfort during nonsedated flexible sigmoidoscopy: a randomized, placebo-controlled clinical trial.
Topics: Administration, Topical; Adolescent; Adult; Aged; Anesthesia, Local; Anxiety; Female; Humans; Lidoca | 2012 |
Comparison of local anesthetic effects of lidocaine versus tramadol and effect of child anxiety on pain level in circumcision procedure.
Topics: Anesthetics, Local; Anxiety; Child; Circumcision, Male; Humans; Lidocaine; Male; Pain, Postoperative | 2013 |
Effective reduction of anxiety and pain during venous cannulation in children: a comparison of analgesic efficacy conferred by nitrous oxide, EMLA and combination.
Topics: Adolescent; Analysis of Variance; Anesthetics, Combined; Anesthetics, Inhalation; Anesthetics, Local | 2003 |
Prevalence and characteristics of pain induced by percutaneous liver biopsy.
Topics: Adult; Aged; Anesthetics, Local; Anti-Anxiety Agents; Anxiety; Biopsy; Diazepam; Female; Humans; Lid | 2003 |
Prevalence and characteristics of pain induced by percutaneous liver biopsy.
Topics: Adult; Aged; Anesthetics, Local; Anti-Anxiety Agents; Anxiety; Biopsy; Diazepam; Female; Humans; Lid | 2003 |
Prevalence and characteristics of pain induced by percutaneous liver biopsy.
Topics: Adult; Aged; Anesthetics, Local; Anti-Anxiety Agents; Anxiety; Biopsy; Diazepam; Female; Humans; Lid | 2003 |
Prevalence and characteristics of pain induced by percutaneous liver biopsy.
Topics: Adult; Aged; Anesthetics, Local; Anti-Anxiety Agents; Anxiety; Biopsy; Diazepam; Female; Humans; Lid | 2003 |
Prevalence and characteristics of pain induced by percutaneous liver biopsy.
Topics: Adult; Aged; Anesthetics, Local; Anti-Anxiety Agents; Anxiety; Biopsy; Diazepam; Female; Humans; Lid | 2003 |
Prevalence and characteristics of pain induced by percutaneous liver biopsy.
Topics: Adult; Aged; Anesthetics, Local; Anti-Anxiety Agents; Anxiety; Biopsy; Diazepam; Female; Humans; Lid | 2003 |
Prevalence and characteristics of pain induced by percutaneous liver biopsy.
Topics: Adult; Aged; Anesthetics, Local; Anti-Anxiety Agents; Anxiety; Biopsy; Diazepam; Female; Humans; Lid | 2003 |
Prevalence and characteristics of pain induced by percutaneous liver biopsy.
Topics: Adult; Aged; Anesthetics, Local; Anti-Anxiety Agents; Anxiety; Biopsy; Diazepam; Female; Humans; Lid | 2003 |
Prevalence and characteristics of pain induced by percutaneous liver biopsy.
Topics: Adult; Aged; Anesthetics, Local; Anti-Anxiety Agents; Anxiety; Biopsy; Diazepam; Female; Humans; Lid | 2003 |
Prevalence and characteristics of pain induced by percutaneous liver biopsy.
Topics: Adult; Aged; Anesthetics, Local; Anti-Anxiety Agents; Anxiety; Biopsy; Diazepam; Female; Humans; Lid | 2003 |
Prevalence and characteristics of pain induced by percutaneous liver biopsy.
Topics: Adult; Aged; Anesthetics, Local; Anti-Anxiety Agents; Anxiety; Biopsy; Diazepam; Female; Humans; Lid | 2003 |
Prevalence and characteristics of pain induced by percutaneous liver biopsy.
Topics: Adult; Aged; Anesthetics, Local; Anti-Anxiety Agents; Anxiety; Biopsy; Diazepam; Female; Humans; Lid | 2003 |
Prevalence and characteristics of pain induced by percutaneous liver biopsy.
Topics: Adult; Aged; Anesthetics, Local; Anti-Anxiety Agents; Anxiety; Biopsy; Diazepam; Female; Humans; Lid | 2003 |
Prevalence and characteristics of pain induced by percutaneous liver biopsy.
Topics: Adult; Aged; Anesthetics, Local; Anti-Anxiety Agents; Anxiety; Biopsy; Diazepam; Female; Humans; Lid | 2003 |
Prevalence and characteristics of pain induced by percutaneous liver biopsy.
Topics: Adult; Aged; Anesthetics, Local; Anti-Anxiety Agents; Anxiety; Biopsy; Diazepam; Female; Humans; Lid | 2003 |
Prevalence and characteristics of pain induced by percutaneous liver biopsy.
Topics: Adult; Aged; Anesthetics, Local; Anti-Anxiety Agents; Anxiety; Biopsy; Diazepam; Female; Humans; Lid | 2003 |
Effectiveness of lidocaine lubricant for discomfort during pediatric urethral catheterization.
Topics: Anesthetics, Local; Anxiety; Child; Child Behavior; Child, Preschool; Double-Blind Method; Female; H | 2003 |
The use of topical anaesthesia at children's minor lacerations: an experimental study.
Topics: Administration, Topical; Adolescent; Anesthesia, Local; Anesthetics, Local; Anxiety; Child; Female; | 2004 |
Lidocaine vaginal gel versus lidocaine paracervical block for analgesia during oocyte retrieval.
Topics: Administration, Intravaginal; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Anxiety; Female; F | 2004 |
Innoxious removal of suction drains.
Topics: Adolescent; Aged; Anesthesia, Local; Anesthetics, Local; Anxiety; Arthroplasty, Replacement, Hip; Ch | 2004 |
Increased placebo analgesia over time in irritable bowel syndrome (IBS) patients is associated with desire and expectation but not endogenous opioid mechanisms.
Topics: Adult; Analgesia; Anesthetics, Local; Anxiety; Attitude to Health; Female; Humans; Irritable Bowel S | 2005 |
Nitrous oxide inhalation is a safe and effective way to facilitate procedures in paediatric outpatient departments.
Topics: Adolescent; Analgesics; Anesthetics, Inhalation; Anxiety; Catheterization; Child; Female; Humans; Li | 2005 |
Is topical local anaesthesia necessary when performing paediatric flexible nasendoscopy? A double-blind randomized controlled trial.
Topics: Administration, Topical; Anesthetics, Local; Anxiety; Child; Double-Blind Method; Drug Combinations; | 2007 |
Is the pain level of patients affected by anxiety during transrectal prostate needle biopsy?
Topics: Aged; Anesthetics, Local; Anxiety; Biopsy, Needle; Humans; Lidocaine; Male; Middle Aged; Pain Measur | 2008 |
The use of topical 4% lidocaine in spheno-palatine ganglion blocks for the treatment of chronic muscle pain syndromes: a randomized, controlled trial.
Topics: Administration, Topical; Adult; Anxiety; Autonomic Nerve Block; Chronic Disease; Depression; Double- | 1995 |
A randomized, controlled trial of oral midazolam and buffered lidocaine for suturing lacerations in children (the SLIC Trial).
Topics: Administration, Oral; Anesthesia, Local; Anxiety; Buffers; Child; Child, Preschool; Double-Blind Met | 1995 |
The effects of intraurethral lidocaine anesthetic and patient anxiety on pain perception during cystoscopy.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anxiety; Cystoscopy; Double-Blind Method; Female; | 1994 |
A comparison of EMLA cream versus nitrous oxide for pediatric venous cannulation.
Topics: Administration, Topical; Analgesics, Non-Narcotic; Anesthetics, Local; Anxiety; Catheterization, Per | 1995 |
Bilateral block: is it safe and more efficient during removal of third molars?
Topics: Absenteeism; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Anxiety; Conscious Sedation; | 1996 |
Determinants of success and failure of EMLA.
Topics: Administration, Topical; Adolescent; Adolescent Behavior; Anesthetics; Anxiety; Bandages; Catheteriz | 1996 |
Determinants of success and failure of EMLA.
Topics: Administration, Topical; Adolescent; Adolescent Behavior; Anesthetics; Anxiety; Bandages; Catheteriz | 1996 |
Determinants of success and failure of EMLA.
Topics: Administration, Topical; Adolescent; Adolescent Behavior; Anesthetics; Anxiety; Bandages; Catheteriz | 1996 |
Determinants of success and failure of EMLA.
Topics: Administration, Topical; Adolescent; Adolescent Behavior; Anesthetics; Anxiety; Bandages; Catheteriz | 1996 |
EMLA cream as a topical anesthetic before office phlebotomy in children.
Topics: Adolescent; Ambulatory Care; Anesthetics, Local; Anxiety; Child; Child, Preschool; Double-Blind Meth | 1996 |
Maternal experience during epidural or combined spinal-epidural anesthesia for cesarean section: a prospective, randomized trial.
Topics: Adult; Analgesics, Opioid; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesth | 1997 |
Saline with benzyl alcohol as intradermal anesthesia for intravenous line placement in children.
Topics: Adolescent; Anesthesia, Local; Anesthetics, Local; Anxiety; Benzyl Alcohol; Child; Drug Combinations | 1998 |
Evaluation of anxiolysis and pain associated with combined peri- and retrobulbar eye block for cataract surgery.
Topics: Aged; Alprazolam; Anesthesia, Local; Anesthetics, Local; Anti-Anxiety Agents; Anxiety; Bromazepam; B | 1998 |
[Combination of Emla cream and nitrous oxide for venous cannulation in children].
Topics: Administration, Cutaneous; Anesthesia, Inhalation; Anesthesia, Local; Anesthetics, Combined; Anesthe | 1997 |
Cerebral protection by lidocaine during cardiac operations.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Anxiety; Brain Diseases; Depression; Double-Blind Method; Femal | 1999 |
Efficacy of parental application of eutectic mixture of local anesthetics for intravenous insertion.
Topics: Adolescent; Anesthesia, Local; Anesthetics, Local; Anxiety; Child; Child, Preschool; Female; Humans; | 1999 |
Comparison of lignocaine-prilocaine cream and amethocaine gel for local analgesia before venepuncture in children.
Topics: Adolescent; Analgesia; Anesthetics, Combined; Anesthetics, Local; Anxiety; Child; Child, Preschool; | 1999 |
Our experience with EMLA Cream (for painless venous cannulation in children).
Topics: Anesthetics, Local; Anxiety; Catheterization, Peripheral; Child; Child, Preschool; Drug Combinations | 1990 |
Reduction of pain at venous cannulation in children with a eutectic mixture of lidocaine and prilocaine (EMLA cream): comparison with placebo cream and no local premedication.
Topics: Administration, Cutaneous; Anesthetics, Local; Anxiety; Catecholamines; Catheterization, Peripheral; | 1987 |
44 other studies available for lidocaine and Anxiety
| Article | Year |
|---|---|
Remediation of chronic immobilization stress-induced negative affective behaviors and altered metabolism of monoamines in the prefrontal cortex by inactivation of basolateral amygdala.
Topics: Animals; Anxiety; Basolateral Nuclear Complex; Behavior, Animal; Biogenic Monoamines; Depression; Ib | 2020 |
A Pilot Study to Understand the Adolescent Pain Experience During Contraceptive Implant Insertion.
Topics: Adolescent; Anesthetics, Local; Anxiety; Cohort Studies; Contraceptive Agents, Female; Desogestrel; | 2021 |
The Effect on Pain and Anxiety of Hot Pad Applied to Patients During Transrectal Prostate Biopsy.
Topics: Anesthetics, Local; Anxiety; Biopsy; Humans; Hyperthermia, Induced; Lidocaine; Male; Pain; Pain Meas | 2021 |
Basolateral amygdalar inactivation blocks chronic stress-induced lamina-specific reduction in prefrontal cortex volume and associated anxiety-like behavior.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Anxiety; Avoidance Learning; Basolateral Nuclear | 2019 |
Effects of lidocaine on adult zebrafish behavior and brain acetylcholinesterase following peripheral and systemic administration.
Topics: Acetylcholinesterase; Animals; Anxiety; Behavior, Animal; Brain; Exploratory Behavior; Female; Lidoc | 2019 |
Comparison of efficacy of neural therapy and physical therapy in chronic low back pain.
Topics: Activities of Daily Living; Adult; Anxiety; Depression; Disability Evaluation; Female; Humans; Injec | 2013 |
Genesis of anxiety, depression, and ongoing abdominal discomfort in ulcerative colitis-like colon inflammation.
Topics: Abdominal Pain; Action Potentials; Anesthetics, Local; Animals; Anxiety; Behavior, Animal; Colitis, | 2015 |
Prevalence and impact on quality of life of post-herpetic neuralgia in French medical centers specialized in chronic pain management: the ZOCAD study.
Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Analgesics; Anesthetics, Local; Anticonvu | 2014 |
The smell of "anxiety": Behavioral modulation by experimental anosmia in zebrafish.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Antidepressive Agents, Second-Generation; Anxiety | 2016 |
Evaluation of heat hyperalgesia and anxiety like-behaviors in a rat model of orofacial cancer.
Topics: Analgesics; Animals; Anti-Anxiety Agents; Anxiety; Cell Line, Tumor; Facial Neoplasms; Hot Temperatu | 2016 |
[Value of nitrous oxide-oxygen mixture (Entonox) in transrectal prostate biopsies].
Topics: Administration, Inhalation; Administration, Rectal; Aged; Anxiety; Biopsy; Gels; Humans; Lidocaine; | 2008 |
Effects of reversible inactivation of the medial septum on rat exploratory behavior in the elevated plus-maze using a test-retest paradigm.
Topics: Anesthetics, Local; Animals; Anxiety; Exploratory Behavior; Lidocaine; Male; Maze Learning; Memory; | 2010 |
Short- and long-term anxiogenic effects induced by a single injection of subconvulsant doses of pilocarpine in rats: investigation of the putative role of hippocampal pathways.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Anxiety; Behavior, Animal; Dose-Response Relation | 2010 |
Judging pain sensitivity with subcutaneous lidocaine injections.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anesthetics, Local; Anxiety; Behavior; Female; H | 2011 |
Clinical characteristics and patterns of healthcare utilization in patients with painful neuropathic disorders in UK general practice: a retrospective cohort study.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory Agents, Non-Stero | 2012 |
High and abnormal forms of aggression in rats with extremes in trait anxiety--involvement of the dopamine system in the nucleus accumbens.
Topics: Aggression; Animals; Animals, Inbred Strains; Anxiety; Brain; Dopamine Antagonists; Dopaminergic Neu | 2012 |
Patients' perspective of wide-awake hand surgery--100 consecutive cases.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anxiety; Consciousness; Epinephrine; Female; Han | 2013 |
Frequency and intensity of pain related to thyroid nodule fine-needle aspiration cytology.
Topics: Acetaminophen; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Ambulatory Care Facilities; | 2013 |
Do unto others--why I would want anesthesia for my prostate biopsy.
Topics: Analgesia; Anxiety; Biopsy, Needle; Humans; Lidocaine; Male; Nerve Block; Pain; Prostate; Randomized | 2003 |
Differential effects of infralimbic vs. ventromedial orbital PFC lidocaine infusions in CD-1 mice on defensive responding in the mouse defense test battery and rat exposure test.
Topics: Anesthetics, Local; Animals; Anxiety; Behavior, Animal; Brain Mapping; Discrimination Learning; Esca | 2004 |
Relief of pain and anxiety in pediatric patients in emergency medical systems.
Topics: Administration, Oral; Analgesics; Anesthetics, Combined; Anxiety; Child; Conscious Sedation; Emergen | 2004 |
Relief of pain and anxiety in pediatric patients in emergency medical systems.
Topics: Administration, Oral; Analgesics; Anesthetics, Combined; Anxiety; Child; Conscious Sedation; Emergen | 2004 |
Relief of pain and anxiety in pediatric patients in emergency medical systems.
Topics: Administration, Oral; Analgesics; Anesthetics, Combined; Anxiety; Child; Conscious Sedation; Emergen | 2004 |
Relief of pain and anxiety in pediatric patients in emergency medical systems.
Topics: Administration, Oral; Analgesics; Anesthetics, Combined; Anxiety; Child; Conscious Sedation; Emergen | 2004 |
Relief of pain and anxiety in pediatric patients in emergency medical systems.
Topics: Administration, Oral; Analgesics; Anesthetics, Combined; Anxiety; Child; Conscious Sedation; Emergen | 2004 |
Relief of pain and anxiety in pediatric patients in emergency medical systems.
Topics: Administration, Oral; Analgesics; Anesthetics, Combined; Anxiety; Child; Conscious Sedation; Emergen | 2004 |
Relief of pain and anxiety in pediatric patients in emergency medical systems.
Topics: Administration, Oral; Analgesics; Anesthetics, Combined; Anxiety; Child; Conscious Sedation; Emergen | 2004 |
Relief of pain and anxiety in pediatric patients in emergency medical systems.
Topics: Administration, Oral; Analgesics; Anesthetics, Combined; Anxiety; Child; Conscious Sedation; Emergen | 2004 |
Relief of pain and anxiety in pediatric patients in emergency medical systems.
Topics: Administration, Oral; Analgesics; Anesthetics, Combined; Anxiety; Child; Conscious Sedation; Emergen | 2004 |
Re: the use of a fine-gauge needle reduces pain in open carpal tunnel decompression: a randomized controlled trial. Watts AC, McEachan J (2005). Journal of Hand Surgery, 30B: 6: 615-617.
Topics: Anesthesia, Local; Anesthetics, Local; Anxiety; Buffers; Carpal Tunnel Syndrome; Decompression, Surg | 2006 |
Further evidence that anxiety and memory are regionally dissociated within the hippocampus.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Anxiety; Avoidance Learning; Behavior, Animal; Br | 2006 |
Predictors of topical anesthetic effectiveness in children.
Topics: Administration, Topical; Age Factors; Anesthetics, Local; Anxiety; Catheterization, Peripheral; Chil | 2007 |
Liver biopsy: is the pain for real or is it only the fear of it?
Topics: Adult; Aged; Anesthetics, Local; Anxiety; Biopsy, Needle; Fear; Female; Health Knowledge, Attitudes, | 2007 |
Anxiolytic-like effects induced by medial prefrontal cortex inhibition in rats submitted to the Vogel conflict test.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Anxiety; Avoidance Learning; Cobalt; Conflict, Ps | 2008 |
Activation of septal 5-HT1A receptors alters spatial memory encoding, interferes with consolidation, but does not affect retrieval in rats subjected to a water-maze task.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Anesthetics, Local; Animals; Anxiety; | 2008 |
[Local anesthesia in gynecological practice].
Topics: Adolescent; Adult; Aged; Anesthesia, Local; Anxiety; Atropine; Diazepam; Female; Genital Diseases, F | 1980 |
[Minor toxic effects of local anaesthetics. 7 cases (author's transl)].
Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Anxiety; Drug Hypersensitivity; Female; Humans; Hyper | 1980 |
Fit with finger block.
Topics: Anxiety; Fingers; Humans; Lidocaine; Nerve Block; Seizures; Syncope | 1993 |
Throat spray for upper gastrointestinal endoscopy is quite acceptable to patients.
Topics: Adolescent; Adult; Aerosols; Aged; Aged, 80 and over; Anesthesia, Local; Anxiety; Conscious Sedation | 1996 |
Development of a sedation policy for upper GI endoscopy based on an audit of patients' perception of the procedure.
Topics: Administration, Topical; Anesthetics, Local; Anxiety; Choice Behavior; Diazepam; Endoscopy, Gastroin | 1996 |
Preoperative anxiety is associated with a high incidence of problematic behavior on emergence after halothane anesthesia in boys.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Local; Anxiety; Awareness; Bupivacaine | 1999 |
Preoperative anxiety is associated with a high incidence of problematic behavior on emergence after halothane anesthesia in boys.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Local; Anxiety; Awareness; Bupivacaine | 1999 |
Preoperative anxiety is associated with a high incidence of problematic behavior on emergence after halothane anesthesia in boys.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Local; Anxiety; Awareness; Bupivacaine | 1999 |
Preoperative anxiety is associated with a high incidence of problematic behavior on emergence after halothane anesthesia in boys.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Local; Anxiety; Awareness; Bupivacaine | 1999 |
Role of the dorsomedial hypothalamus in mediating the response to benzodiazepines on trial 2 in the elevated plus-maze test of anxiety.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Chlordiazepoxide; Dorsomedial Hypothalamic Nucleus; Functiona | 1999 |
Comparative study of distraction versus topical anesthesia for pediatric pain management during immunizations.
Topics: Anesthetics, Local; Anxiety; Child; Child Behavior; Female; Humans; Immunization; Lidocaine; Lidocai | 1999 |
Topical pharyngeal anesthesia during gastroscopy.
Topics: Anesthesia, Local; Anesthetics, Local; Anxiety; Gastroscopy; Humans; Larynx; Lidocaine; Midazolam; P | 2001 |
Fit with finger block.
Topics: Anxiety; Epilepsy; Female; Fingers; Humans; Hyperventilation; Lidocaine; Male; Nerve Block | 1992 |
Iontophoresis versus subcutaneous injection: a comparison of two methods of local anesthesia delivery in children.
Topics: Adolescent; Adult; Anesthetics, Local; Anxiety; Child; Female; Humans; Injections, Subcutaneous; Ion | 1991 |
Restless leg syndrome: unusual cause of agitation under anesthesia.
Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Anxiety; Female; Humans; Infant, Newborn; Lidocaine; | 1987 |
A new method for measuring the stress effects in minor oral surgery.
Topics: Achilles Tendon; Action Potentials; Anesthesia, Local; Anxiety; Electrocardiography; Electromagnetic | 1974 |
Pre-hospital management of acute myocardial infarction.
Topics: Acute Disease; Anxiety; Atropine; Communication; Heart Massage; Heparin; Home Care Services; Humans; | 1973 |
Drug therapy in the coronary care unit--how much is really necessary?
Topics: Analgesics; Anxiety; Arrhythmias, Cardiac; Coronary Care Units; Digoxin; Diuretics; Heparin; Home Ca | 1973 |
Management of rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Amitriptyline; Anxiety; Arthritis, Rheumatoid; Aspirin; Attitude of Health | 1969 |
Bronchoscopy with the aid of diazepam.
Topics: Adolescent; Adult; Aged; Amnesia; Anxiety; Blood Pressure; Bronchoscopy; Consciousness; Diazepam; Fe | 1969 |