Page last updated: 2024-10-28

lidocaine and Ankle Injuries

lidocaine has been researched along with Ankle Injuries in 9 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Ankle Injuries: Harm or hurt to the ankle or ankle joint usually inflicted by an external source.

Research Excerpts

ExcerptRelevanceReference
" The results of this study led us to conclude that the hematoma block with or without supplemental analgesia for the manipulation of ankle fractures was safe and effective and is a useful technique."1.29Hematoma block for ankle fractures: a safe and efficacious technique for manipulations. ( Alioto, RJ; Furia, JP; Marquardt, JD, 1995)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19902 (22.22)18.7374
1990's2 (22.22)18.2507
2000's3 (33.33)29.6817
2010's2 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sin, B1
Gritsenko, D1
Tam, G1
Koop, K1
Mok, E1
Mohammed, A1
Down, S1
Waddington, G1
Adams, R1
Thomson, M1
Fullerton, BD1
White, BJ1
Walsh, M1
Egol, KA1
Tejwani, NC1
Alioto, RJ1
Furia, JP1
Marquardt, JD1
Farquhar, I1
Fairclough, JA1
Fitzgerald, M1
Millard, C1
McIntosh, N1
Brady, TA1
Arnold, A1

Clinical Trials (7)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Rotator Cuff Tendinopathy: A Randomized and Blinded Comparison of Superficial and Deep Injection Methods[NCT01402011]77 participants (Actual)Interventional2010-11-30Completed
The Effect of Intra-articular Local Anesthetic Injection and Hematoma Aspiration on Pain and Narcotic Analgesia Use Following Tibial Plateau Fractures[NCT02951884]Phase 42 participants (Actual)Interventional2016-06-15Terminated (stopped due to The study was stopped for feasibility (low enrollment))
Postoperative Pain Control in Extracapsular Hip Fracture Patients: Fascia Iliaca Compartment Block Versus Fracture Block[NCT04335461]Early Phase 10 participants (Actual)Interventional2021-08-05Withdrawn (stopped due to Study was withdrawn. Study expired in IRB system and no patients enrolled as per institutional CTMS and IRB systems. Primary and Study Completion Dates reflect date IRB approval expired.)
Efficacy of Hematoma Block on Postoperative Pain After Femoral Intramedullary Rodding: A Randomized Trial[NCT04860856]Phase 488 participants (Actual)Interventional2019-08-17Completed
"Comparison of Ultrasound-guided Hematoma Block and Blind Hematoma Block for Analgesia in Distal Radius Fractures"[NCT02346929]115 participants (Anticipated)Interventional2014-08-31Recruiting
Diagnostic Accuracy of the Vegetative and Minimally Conscious State: Clinical Consensus Versus Standardized Neurobehavioral Assessment[NCT04139239]150 participants (Actual)Observational2017-07-01Completed
The Efficacy of the Eutectic Mixture of Local Anesthetics (EMLA) Cream Versus the Synera Patch for Pain Reduction During Venipuncture in Children[NCT00530803]Phase 2100 participants (Actual)Interventional2007-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change From Baseline in Maximum Pain Score at 9 Months

Participants were asked about pain at rest, at work, doing sports. The maximum pain reported on a scale ranging from 0 (no pain at all) to 10 (extreme pain) was recorded for each participant. Maximum of pain scores rest, work, sport recorded. Calculated as pain at baseline - pain at 9 months. (NCT01402011)
Timeframe: baseline and 9 months

Interventionunits on a scale (Mean)
25% Dextrose in Ligaments and Tendons2.9
.1% Lidocaine in Ligaments and Tendons1.8
.1% Lidocaine Subcutaneous1.3

Change From Baseline of Visual Analog Pain Scale at 3 Months

Subject marks his pain level at rest, at work, doing sports on a 10 cm scale. Maximum of pain scores rest, work, sport recorded. Calculated as pain at baseline - pain at 3 months. VAS scale is from 0 = no pain to 10 = maximum pain (NCT01402011)
Timeframe: baseline and three months

Interventionunits on a scale (Mean)
25% Dextrose in Ligaments and Tendons3.0
.1% Lidocaine in Ligaments and Tendons2.7
.1% Lidocaine Subcutaneous2.7

Nine Month Satisfaction Questionnaire

Phone call asking how satisfied were they with their treatment 10 = extremely satisfied, 0 = extremely dissatisfied ) (NCT01402011)
Timeframe: Nine months after first injection treatment appointment

Interventionunits on a scale (Mean)
25% Dextrose in Ligaments and Tendons6.7
.1% Lidocaine in Ligaments and Tendons4.7
.1% Lidocaine Subcutaneous3.9

Visual Analog Pain Scale 0= no Pain 10 = Maximum Pain

Subject marks his pain level at rest, at work, doing sports on a 10 cm scale. The maximum pain level among the 3 different activities was recorded. (NCT01402011)
Timeframe: 20 minutes before first injection on first day of patient visit

Interventionunits on a scale (Mean)
25% Dextrose in Shoulder Entheses7.3
.1% Lidocaine in Shoulder Entheses6.9
.1% Lidocaine Subcu. Above Shouldr Enth.6.9

Disabilities of the Arm Shoulder and Hand Questionnaire

http://www.dash.iwh.on.ca/assets/images/pdfs/DASH_quest06.pdf 30 questions assessing ability to use shoulder in everyday activities, each question scored 1 to 5, where one is normal, no problem and five is unable to perform. No data was collected at 9 months. The score ranges from 30 to 150. Higher scores represent worse outcomes. (NCT01402011)
Timeframe: 20 minutes before the first injection and at 3 months

,,
Interventionunits on a scale (Mean)
Baseline3 months
.1% Lidocaine in Ligaments and Tendons71.354.7
.1% Lidocaine Subcutaneous69.661
25% Dextrose in Ligaments and Tendons72.461.3

Physical Examination of the Shoulder Scale

From Steven W. Brose, DO, Michael L. Boninger, MD, Bradley Fullerton, MD, Thane McCann, MD, From: Jennifer L. Collinger, BSE, Bradley G. Impink, BSE, Trevor A. Dyson-Hudson, MD Shoulder ultrasound abnormalities, physical examination findings, and pain in manual wheelchair users with spinal cord injury. Arch Phys Med Rehabil 2008 Nov; 89:2086-93, appendix 1 12 parameters of shoulder examination: Biceps tendon/bicipital groove tenderness, Supraspinatus tendon/greater tuberosity tenderness Acromioclavicular joint tenderness Resisted external rotation. Resisted internal rotation. Supraspinatus test. Painful Arc Test. Neer impingement sign. Hawkins-Kennedy impingement sign. O'Brien Active Compression Test for AC Joint Pathology O'Brien Active Compression Test for Labral Pathology impingement sign. each test scored 0 = no pain, 1 = tenderness, 2 = pain. All 12 scores added. Range 0-24. Higher scores = more pathology (NCT01402011)
Timeframe: 20 minutes before first injection on first day of patient visit and at 3 months

,,
Interventionunits on a scale (Mean)
Baseline3 months
.1% Lidocaine in Ligaments and Tendons13.110.7
.1% Lidocaine Subcutaneous1312.9
25% Dextrose in Ligaments and Tendons13.211.4

Rotator Cuff Ultrasound, Ultrasound Shoulder Pathology Rating Scale

"From Brose et al. shoulder ultrasound abnormalities, physical examination findings, and pain in manual wheelchair users with spinal cord injury Arch Phys Med Rehabil 2008 Nov, 89: 2086-93 appendix 2. rates biceps tendinopathy (0-6), supraspinatus tendinopathy (0-5), greater tuberosity the cortical surface (0-3), dynamics supraspinatus impingement (0-3), dynamic subscapularis/ biceps/ coracoid impingement (0-3). The total score ranged from 0 to 20 with higher scores indicating a worse outcome. The change was calculated by taking the final score - the baseline score." (NCT01402011)
Timeframe: 20 minutes before first injection on first day of patient visit and at on average 9.4 months

,,
Interventionunits on a scale (Mean)
Baselinechange at 9.4 +/- 2.2 months
.1% Lidocaine in Ligaments and Tendons4.3-0.6
.1% Lidocaine Subcutaneous4.3-0.6
25% Dextrose in Ligaments and Tendons4.0-0.3

Numerical Rating Scale (NRS) Pain Scores

Twenty-four hours after injury, patients will self report their numerical rating scale (NRS) score. The NRS score ranges from 0 to 10 with higher scores indicating greater pain. (NCT02951884)
Timeframe: 24 hours

Interventionunits on a scale (Number)
Aspiration With Injection7
Control2

Supplemental Analgesia

Twenty-four hours after injury, the researchers will record the number of participants that required supplemental analgesia. (NCT02951884)
Timeframe: 24 hours

InterventionParticipants (Count of Participants)
Aspiration0
Aspiration With Injection0
Control1

Blinded Observer's Subjective Ratings of Participants' Pain Level at Tourniquet Placement, Using a 6-point NRS

The NRS (Numerical Rating Scale) is a 6-point rating scale where 0= no pain and 5 = worst pain. Blinded observers reported their own subjective evaluation of the level of pain experienced by the participants at tourniquet placement. Total number of participants subjectively evaluated as experiencing each pain level is reported. (NCT00530803)
Timeframe: before venipuncture

,
InterventionParticipants (Count of Participants)
Participants evaluated at NRS = 0 (No pain)Participants evaluated at NRS = 1Participants evaluated at NRS = 2Participants evaluated at NRS = 3Participants evaluated at NRS = 4Participants evaluated at NRS = 5
EMLA Cream4162100
Synera Patch3765110

Blinded Observer's Subjective Ratings of the Participant's Pain Level at 5 Minutes Post Venipuncture Procedure, Using a 6-point NRS

The NRS (Numerical Rating Scale) is a 6-point rating scale where 0= no pain and 5 = worst pain. Blinded observers reported their own subjective evaluation of the level of pain participants were experiencing 5 minutes after the venipuncture was completed. Total number of participants subjectively evaluated as experiencing each pain level is reported. (NCT00530803)
Timeframe: 5 minutes post venipuncture

,
InterventionParticipants (Count of Participants)
Participants evaluated at NRS = 0 (No pain)Participants evaluated at NRS = 1Participants evaluated at NRS = 2Participants evaluated at NRS = 3Participants evaluated at NRS = 4Participants evaluated at NRS = 5
EMLA Cream4531100
Synera Patch4541000

Blinded Observer's Subjective Ratings of the Participant's Pain Level at Needle Insertion, Using a 6-point NRS

The NRS (Numerical Rating Scale) is a 6-point rating scale where 0= no pain and 5 = worst pain. Blinded observers reported their own subjective evaluation of the level of pain experienced by the participants at needle insertion. Total number of participants subjectively evaluated as experiencing each pain level is reported. (NCT00530803)
Timeframe: during needle insertion

,
InterventionParticipants (Count of Participants)
Participants evaluated at NRS = 0 (No pain)Participants evaluated at NRS = 1Participants evaluated at NRS = 2Participants evaluated at NRS = 3Participants evaluated at NRS = 4Participants evaluated at NRS = 5
EMLA Cream32142200
Synera Patch25129220

Parent Rating of Child's Pain Using a 6-point NRS

The Numerical Rating Scale (NRS) is a 6-point rating scale where 0= no pain and 5 = worst pain. Parents reported their own subjective evaluation of participants pain level. Each participant had only one parental assessment. Total number of parental assessment for each pain level on the 6-point NRS is reported as total number of participants experiencing that pain level. (NCT00530803)
Timeframe: immediately after venipuncture is completed

,
InterventionParticipants (Count of Participants)
number of participants with NRS=0 (no pain)number of participants with NRS=1number of participants with NRS=2number of participants with NRS=3number of participants with NRS=4number of participants with NRS=5
EMLA Cream4261100
Synera Patch4151201

Participants Self-rating of Pain Using the Wong-Baker FACES Pain Rating Scale.

"Participants were asked to report their level of pain using a 6-point Wong-Baker FACES Pain Rating Scale ranging from 0, no pain, to 5, the most pain you can have. The Wong-Baker FACES Pain Rating Scale is a validated tool for measuring pain in patients as young as 3 years old. A FACES pain score less than or equal to 2 is considered no pain to mild pain, and is clinically acceptable. Studies have shown average FACES pain scores for children receiving vascular access with placebo to be 2.2 to 3.5." (NCT00530803)
Timeframe: immediately after completion of venipuncture

,
InterventionParticipants (Count of Participants)
Participants with FACES Score = 0 (No pain)Participants with FACES Score = 1Participants with FACES Score = 2Participants with FACES Score = 3Participants with FACES Score = 4Participants with FACES Score = 5
EMLA Cream4262000
Synera Patch3883100

Trials

3 trials available for lidocaine and Ankle Injuries

ArticleYear
Movement discrimination after intra-articular local anaesthetic of the ankle joint.
    British journal of sports medicine, 2007, Volume: 41, Issue:8

    Topics: Adolescent; Adult; Anesthetics, Local; Ankle Injuries; Area Under Curve; Athletic Injuries; Cross-Ov

2007
Intra-articular block compared with conscious sedation for closed reduction of ankle fracture-dislocations. A prospective randomized trial.
    The Journal of bone and joint surgery. American volume, 2008, Volume: 90, Issue:4

    Topics: Adult; Aged; Anesthetics, Local; Ankle Injuries; Conscious Sedation; Female; Fractures, Bone; Humans

2008
Intra-articular block compared with conscious sedation for closed reduction of ankle fracture-dislocations. A prospective randomized trial.
    The Journal of bone and joint surgery. American volume, 2008, Volume: 90, Issue:4

    Topics: Adult; Aged; Anesthetics, Local; Ankle Injuries; Conscious Sedation; Female; Fractures, Bone; Humans

2008
Intra-articular block compared with conscious sedation for closed reduction of ankle fracture-dislocations. A prospective randomized trial.
    The Journal of bone and joint surgery. American volume, 2008, Volume: 90, Issue:4

    Topics: Adult; Aged; Anesthetics, Local; Ankle Injuries; Conscious Sedation; Female; Fractures, Bone; Humans

2008
Intra-articular block compared with conscious sedation for closed reduction of ankle fracture-dislocations. A prospective randomized trial.
    The Journal of bone and joint surgery. American volume, 2008, Volume: 90, Issue:4

    Topics: Adult; Aged; Anesthetics, Local; Ankle Injuries; Conscious Sedation; Female; Fractures, Bone; Humans

2008
Cutaneous hypersensitivity following peripheral tissue damage in newborn infants and its reversal with topical anaesthesia.
    Pain, 1989, Volume: 39, Issue:1

    Topics: Anesthetics, Local; Ankle Injuries; Blood Specimen Collection; Double-Blind Method; Drug Combination

1989

Other Studies

6 other studies available for lidocaine and Ankle Injuries

ArticleYear
The Use of Intravenous Lidocaine for the Management of Acute Pain Secondary to Traumatic Ankle Injury: A Case Report.
    Journal of pharmacy practice, 2018, Volume: 31, Issue:1

    Topics: Acute Pain; Adolescent; Anesthetics, Local; Ankle Injuries; Humans; Lidocaine; Male; Pain Management

2018
Towards evidence-based emergency medicine: best BETs from the Manchester Royal Infirmary. Bet 1: ankle lidocaine.
    Emergency medicine journal : EMJ, 2011, Volume: 28, Issue:5

    Topics: Accidental Falls; Anesthetics, Local; Ankle Injuries; Evidence-Based Emergency Medicine; Fractures,

2011
High-resolution ultrasound and magnetic resonance imaging to document tissue repair after prolotherapy: a report of 3 cases.
    Archives of physical medicine and rehabilitation, 2008, Volume: 89, Issue:2

    Topics: Adolescent; Adult; Anesthetics, Local; Ankle Injuries; Athletic Injuries; Chronic Disease; Female; G

2008
Hematoma block for ankle fractures: a safe and efficacious technique for manipulations.
    Journal of orthopaedic trauma, 1995, Volume: 9, Issue:2

    Topics: Adolescent; Adult; Aged; Anesthesia, Intravenous; Anesthesia, Local; Ankle Injuries; Child; Female;

1995
Hematoma block for ankle fractures: a safe and efficacious technique for manipulations.
    Journal of orthopaedic trauma, 1995, Volume: 9, Issue:2

    Topics: Adolescent; Adult; Aged; Anesthesia, Intravenous; Anesthesia, Local; Ankle Injuries; Child; Female;

1995
Hematoma block for ankle fractures: a safe and efficacious technique for manipulations.
    Journal of orthopaedic trauma, 1995, Volume: 9, Issue:2

    Topics: Adolescent; Adult; Aged; Anesthesia, Intravenous; Anesthesia, Local; Ankle Injuries; Child; Female;

1995
Hematoma block for ankle fractures: a safe and efficacious technique for manipulations.
    Journal of orthopaedic trauma, 1995, Volume: 9, Issue:2

    Topics: Adolescent; Adult; Aged; Anesthesia, Intravenous; Anesthesia, Local; Ankle Injuries; Child; Female;

1995
Sciatic block in lower limb surgery.
    Injury, 1990, Volume: 21, Issue:2

    Topics: Adolescent; Adult; Aged; Ankle Injuries; Ankle Joint; Femoral Nerve; Humans; Lidocaine; Male; Middle

1990
Aspiration injection treatment for varus sprain of the ankle. A preliminary report.
    The Journal of bone and joint surgery. American volume, 1972, Volume: 54, Issue:6

    Topics: Ankle; Ankle Injuries; Athletic Injuries; Bandages; Evaluation Studies as Topic; Humans; Hyaluronogl

1972