lidocaine has been researched along with Anemia in 5 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Anemia: A reduction in the number of circulating ERYTHROCYTES or in the quantity of HEMOGLOBIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tocainide is an effective oral antiarrhythmic agent." | 5.27 | Tocainide-induced reversible agranulocytosis and anemia. ( Kadin, ME; Soff, GA, 1987) |
| "Pain was assessed using a visual analogue scale, a verbal descriptive scale and a direct comparison between paired treatments." | 2.67 | Pain after subcutaneous injection of recombinant human erythropoietin: does Emla cream help? ( Coulthard, MG; Hardy, SP; Hughes, C; Matthews, JN; Morris, KP, 1994) |
| "Tocainide is an effective oral antiarrhythmic agent." | 1.27 | Tocainide-induced reversible agranulocytosis and anemia. ( Kadin, ME; Soff, GA, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guay, J | 1 |
| Morris, KP | 1 |
| Hughes, C | 1 |
| Hardy, SP | 1 |
| Matthews, JN | 1 |
| Coulthard, MG | 1 |
| Soff, GA | 1 |
| Kadin, ME | 1 |
| Dudley, AG | 1 |
| Conrad, LL | 1 |
| Markham, SM | 1 |
| Greaves, MW | 1 |
| Birkett, D | 1 |
| Johnson, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Methemoglobin Levels in Generally Anesthetized Pediatric Dental Patients Receiving Prilocaine Versus Lidocaine[NCT01402869] | 91 participants (Actual) | Interventional | 2011-08-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Change in percentage of methemoglobin in blood from baseline level to peak level (NCT01402869)
Timeframe: From administration of local anesthetic or start of restorative procedures to time at which maximum methemoglobin blood level was documented during dental treatment for an average of 2 hours
| Intervention | percentage of methemoglobin in blood (Mean) |
|---|---|
| Prilocaine | 2.73 |
| Lidocaine | 0.78 |
| No Local Anesthetic | 0.76 |
The maximum percentage of methemoglobin in blood (NCT01402869)
Timeframe: Measured at 10 second intervals during dental treatment for an average of 2 hours
| Intervention | percentage of methemoglobin in blood (Mean) |
|---|---|
| Prilocaine | 3.55 |
| Lidocaine | 1.63 |
| No Local Anesthetic | 1.60 |
The length of time between the administration of local anesthetic (Prilocaine and Lidocaine Groups) or start of restorative dental procedures (No local anesthetic Group) and the time at which the maximum methemoglobin blood level is observed. (NCT01402869)
Timeframe: Measured at 10 second intervals during dental treatment for an average of 2 hours
| Intervention | minutes (Mean) |
|---|---|
| Prilocaine | 62.73 |
| Lidocaine | 57.50 |
| No Local Anesthetic | 29.50 |
1 review available for lidocaine and Anemia
| Article | Year |
|---|---|
Methemoglobinemia related to local anesthetics: a summary of 242 episodes.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anemia; Anesthetics, Local; Benzocaine; Chi | 2009 |
1 trial available for lidocaine and Anemia
| Article | Year |
|---|---|
Pain after subcutaneous injection of recombinant human erythropoietin: does Emla cream help?
Topics: Adult; Aged; Anemia; Anesthetics, Local; Double-Blind Method; Drug Combinations; Erythropoietin; Fem | 1994 |
3 other studies available for lidocaine and Anemia
| Article | Year |
|---|---|
Tocainide-induced reversible agranulocytosis and anemia.
Topics: Aged; Agranulocytosis; Anemia; Anti-Arrhythmia Agents; Erythropoiesis; Humans; Lidocaine; Male; Toca | 1987 |
Continuous intrapartum lumbar epidural block: a comparative study employing propitocaine 2 percent, lidocaine 1.5 percent with epinephrine, and 1.5 percent lidocaine.
Topics: Anemia; Anesthesia, Conduction; Anesthesia, Epidural; Anesthesia, Obstetrical; Epinephrine; Female; | 1971 |
Nevus anemicus: a unique catecholamine-dependent nevus.
Topics: Administration, Oral; Adolescent; Adult; Anemia; Angiokeratoma; Blood Vessels; Bradykinin; Capillari | 1970 |