Page last updated: 2024-10-28

lidocaine and Amyotrophic Neuralgia

lidocaine has been researched along with Amyotrophic Neuralgia in 5 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's2 (40.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Stav, A1
Ovadia, L1
Sternberg, A1
Kaadan, M1
Weksler, N1
Dennert, R1
Münzenberg, KJ1
Haase, W1
Palermo, S1
Riello, R1
Cammardella, MP1
Carossino, D1
Orlandini, G1
Casigliani, R1
Launo, C1
Schopen, RD1
Caminiti, G1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Do Cervical Interlaminar Epidural Steroid Injections With Low-dose Lidocaine Cause Transient Objective Upper Extremity Weakness? A Prospective Randomized Controlled Trial[NCT03127137]Phase 4123 participants (Actual)Interventional2018-08-01Completed
Do Cervical Interlaminar Epidural Steroid Injections With Low-dose Lidocaine Cause Transient Objective Upper Extremity Weakness? A Prospective Randomized[NCT03382925]Phase 416 participants (Actual)Interventional2017-12-20Terminated (stopped due to Not enough cervical interlaminar patients who meet criteria in order to meet recruitment goals.)
A Prospective Randomized Comparative Trial of Targeted Injection Via a Transforaminal Approach With Dexamethasone Versus an Epidural Catheter Via an Interlaminar Approach With Particulate Steroid for the Treatment of Cervical Radicular Pain[NCT03382821]Phase 4120 participants (Actual)Interventional2017-09-15Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in Strength in Both Groups After CESI.

Change in strength in both groups greater than or equal to 20% weakness in one or more myotomes 30 minutes after CESI using a hand held Dynamometer. (NCT03127137)
Timeframe: 30 minutes after the CESI procedure

,
InterventionParticipants (Count of Participants)
Yes, greater or equal to 20% weakness in greater or equal to 1 or more myotomeNo, greater or equal to 20% weakness in greater or equal to 1 or more myotome
Experimental Group 1 With Lidocaine2535
Experimental Group 2 With Saline3030

The Percentage of Participants With Reduction of 50% or More of Neck and Arm Pain NRS Score

The Percentage of Participants with Reduction of 50% or More of Neck and Arm Pain NRS score (NCT03382821)
Timeframe: 1 month follow up

Interventionpercentage of participants (Number)
Transforaminal ESI With Dexamethasone49.1
Interlaminar Catheter-targeted ESI With Triamcinolone68.5

"The Percentage of Participants Reporting Patient Global Impression of Change Score of 6-7 (Indicating Much Improved and Very Much Improved)"

"Patient Global Impression of Change is a scale which measures participant reported satisfaction after an intervention. The outcome was measured as the percent of patients reporting a PGIC score of 6-7 (indicating much improved and very much improved)" (NCT03382821)
Timeframe: 1 month, 3 month, 6 month, and 1 year follow up

,
Interventionpercentage of participants (Number)
One monthThree monthsSix monthsOne year
Transforaminal Catheter-targeted ESI With Triamcinolone59575361
Transforaminal ESI With Dexamethasone41425557

Neck Disability Index-5

Percentage of patients with >30% improvement in Neck Disability Index-5 score. (NCT03382821)
Timeframe: 1 month, 3 month, 6 month, and 1 year follow up

,
Interventionpercentage of participants (Number)
One monthThree monthSix monthOne year
Transforaminal Catheter-targeted ESI With Triamcinolone62585660
Transforaminal ESI With Dexamethasone48565547

Percentage of Participants Reporting >6.8 Reduction on the Medication Quantification Scale III

The Medication Quantification Scale (MQS) is an instrument used for clinical and research applications for quantifying medication regimen use in chronic pain populations. A 6.8 point reduction is considered equivalent to 10 morphine eqivalents. (NCT03382821)
Timeframe: 1 month, 3 month, 6 month, and 1 year follow up

,
Interventionpercentage of participants (Number)
One monthThree monthSix monthOne year
Transforaminal Catheter-targeted ESI With Triamcinolone1917198
Transforaminal ESI With Dexamethasone1620157

Trials

2 trials available for lidocaine and Amyotrophic Neuralgia

ArticleYear
Cervical epidural steroid injection for cervicobrachialgia.
    Acta anaesthesiologica Scandinavica, 1993, Volume: 37, Issue:6

    Topics: Adult; Aged; Analgesia, Epidural; Brachial Plexus Neuritis; Cervical Vertebrae; Chronic Disease; Dru

1993
Cervical epidural steroid injection for cervicobrachialgia.
    Acta anaesthesiologica Scandinavica, 1993, Volume: 37, Issue:6

    Topics: Adult; Aged; Analgesia, Epidural; Brachial Plexus Neuritis; Cervical Vertebrae; Chronic Disease; Dru

1993
Cervical epidural steroid injection for cervicobrachialgia.
    Acta anaesthesiologica Scandinavica, 1993, Volume: 37, Issue:6

    Topics: Adult; Aged; Analgesia, Epidural; Brachial Plexus Neuritis; Cervical Vertebrae; Chronic Disease; Dru

1993
Cervical epidural steroid injection for cervicobrachialgia.
    Acta anaesthesiologica Scandinavica, 1993, Volume: 37, Issue:6

    Topics: Adult; Aged; Analgesia, Epidural; Brachial Plexus Neuritis; Cervical Vertebrae; Chronic Disease; Dru

1993
Cervical epidural steroid injection for cervicobrachialgia.
    Acta anaesthesiologica Scandinavica, 1993, Volume: 37, Issue:6

    Topics: Adult; Aged; Analgesia, Epidural; Brachial Plexus Neuritis; Cervical Vertebrae; Chronic Disease; Dru

1993
Cervical epidural steroid injection for cervicobrachialgia.
    Acta anaesthesiologica Scandinavica, 1993, Volume: 37, Issue:6

    Topics: Adult; Aged; Analgesia, Epidural; Brachial Plexus Neuritis; Cervical Vertebrae; Chronic Disease; Dru

1993
Cervical epidural steroid injection for cervicobrachialgia.
    Acta anaesthesiologica Scandinavica, 1993, Volume: 37, Issue:6

    Topics: Adult; Aged; Analgesia, Epidural; Brachial Plexus Neuritis; Cervical Vertebrae; Chronic Disease; Dru

1993
Cervical epidural steroid injection for cervicobrachialgia.
    Acta anaesthesiologica Scandinavica, 1993, Volume: 37, Issue:6

    Topics: Adult; Aged; Analgesia, Epidural; Brachial Plexus Neuritis; Cervical Vertebrae; Chronic Disease; Dru

1993
Cervical epidural steroid injection for cervicobrachialgia.
    Acta anaesthesiologica Scandinavica, 1993, Volume: 37, Issue:6

    Topics: Adult; Aged; Analgesia, Epidural; Brachial Plexus Neuritis; Cervical Vertebrae; Chronic Disease; Dru

1993
[Therapy of cervico-brachialgia. Controlled clinical comparison of a high-dose combination of neurotropic vitamins with an analgesic].
    Fortschritte der Medizin, 1976, Apr-08, Volume: 94, Issue:10

    Topics: Adult; Brachial Plexus Neuritis; Clinical Trials as Topic; Drug Combinations; Female; Humans; Lidoca

1976

Other Studies

3 other studies available for lidocaine and Amyotrophic Neuralgia

ArticleYear
[TENS + mesotherapy association in the therapy of cervico-brachialgia: preliminary data].
    Minerva anestesiologica, 1991, Volume: 57, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Brachial Plexus Neuritis; Colchicine; Combined Modality Therapy; Dic

1991
[Dexamonosone as a rheuma therapeutic agent].
    Munchener medizinische Wochenschrift (1950), 1970, Jul-17, Volume: 29

    Topics: Anti-Inflammatory Agents; Arm; Arthritis; Brachial Plexus Neuritis; Dosage Forms; Erythema Nodosum;

1970
[Therapy of pain in cervicobrachialgia].
    Rassegna internazionale di clinica e terapia, 1966, Oct-31, Volume: 46, Issue:20

    Topics: Autonomic Nerve Block; Brachial Plexus Neuritis; Cervical Plexus; Humans; Lidocaine; Stellate Gangli

1966