lidocaine has been researched along with Amyotrophic Lateral Sclerosis in 3 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cramps were quite easily induced by volitional exertion and high-frequency stimulation of the peripheral nerves." | 1.29 | Muscle cramp as the result of impaired GABA function--an electrophysiological and pharmacological observation. ( Matsuoka, H; Mizoguchi, K; Nishimura, Y; Obi, T; Takatsu, M, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anger, T | 1 |
| Madge, DJ | 1 |
| Mulla, M | 1 |
| Riddall, D | 1 |
| GEJROT, T | 1 |
| Obi, T | 1 |
| Mizoguchi, K | 1 |
| Matsuoka, H | 1 |
| Takatsu, M | 1 |
| Nishimura, Y | 1 |
1 review available for lidocaine and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Medicinal chemistry of neuronal voltage-gated sodium channel blockers.
Topics: Amyotrophic Lateral Sclerosis; Analgesics; Anticonvulsants; Epilepsy; Humans; Ion Channel Gating; Mo | 2001 |
2 other studies available for lidocaine and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
THE INFLUENCE OF XYLOCAINE ON INDUCED AND SPONTANEOUS NYSTAGMUS. A PRELIMINARY REPORT.
Topics: Alcoholism; Amyotrophic Lateral Sclerosis; Brain Neoplasms; Dimenhydrinate; Epilepsy; Lidocaine; Men | 1963 |
Muscle cramp as the result of impaired GABA function--an electrophysiological and pharmacological observation.
Topics: Amyotrophic Lateral Sclerosis; Baclofen; Clomipramine; Diazepam; Electric Stimulation; Evoked Potent | 1993 |