lidocaine has been researched along with Adenocarcinoma in 24 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Adenocarcinoma: A malignant epithelial tumor with a glandular organization.
| Excerpt | Relevance | Reference |
|---|---|---|
| "NCI-H838 lung adenocarcinoma cells were incubated with ropivacaine or lidocaine (1 nM-100 µM) in absence/presence of TNFα (20 ng ml(-1)) for 20 min or 4 h, respectively." | 7.81 | Clinically relevant concentrations of lidocaine and ropivacaine inhibit TNFα-induced invasion of lung adenocarcinoma cells in vitro by blocking the activation of Akt and focal adhesion kinase. ( Beck-Schimmer, B; Borgeat, A; Dull, RO; Minshall, RD; Piegeler, T; Schläpfer, M; Schwartz, DE, 2015) |
| "A patient twice developed the adult respiratory distress syndrome following an adverse reaction to administration of lidocaine." | 7.66 | Adult respiratory distress syndrome following administration of lidocaine. ( Howard, JJ; Mohsenifar, Z; Simons, SM, 1982) |
| "The combination of periprostatic nerve blockade and intrarectal lidocain gel provides a more meaningful pain relief compared to group of patients undergoing intrarectal lidocaine gel." | 5.17 | The effectivity of periprostatic nerve blockade for the pain control during transrectal ultrasound guided prostate biopsy. ( Besiroglu, H; Cakir, SS; Can Polat, E; Dursun, M; Karadeniz, T; Otunctemur, A; Ozbek, E, 2013) |
| "The use of 40% DMSO with lidocaine instilled into the rectal vault for 10 minutes avoids any need for injection and is capable of decreasing the discomfort or pain experienced during probe insertion and prostate biopsy comparable to the perianal and periprostatic protocols." | 5.11 | Comparison of different local anesthesia techniques during TRUS-guided biopsies: a prospective pilot study. ( Ben-Dor, D; Cytron, S; Dorfman, D; Kesari, D; Kravchick, S; Peled, R, 2005) |
| "Lidocaine is the most commonly used local anaesthetic in clinical and can inhibit proliferation, suppress invasion and migration and induce apoptosis in human lung adenocarcinoma (LAD) cells." | 3.85 | Lidocaine inhibits the proliferation of lung cancer by regulating the expression of GOLT1A. ( Cheng, Y; Hu, R; Jiang, H; Sun, Y; Wu, X; Xi, S; Zhang, L, 2017) |
| "NCI-H838 lung adenocarcinoma cells were incubated with ropivacaine or lidocaine (1 nM-100 µM) in absence/presence of TNFα (20 ng ml(-1)) for 20 min or 4 h, respectively." | 3.81 | Clinically relevant concentrations of lidocaine and ropivacaine inhibit TNFα-induced invasion of lung adenocarcinoma cells in vitro by blocking the activation of Akt and focal adhesion kinase. ( Beck-Schimmer, B; Borgeat, A; Dull, RO; Minshall, RD; Piegeler, T; Schläpfer, M; Schwartz, DE, 2015) |
| "A patient with disseminated cancer pain failed to obtain pain relief despite the intravenous infusion of hydromorphone at a rate equivalent to over 7 g of morphine/day." | 3.67 | Failure of epidural opioid to control cancer pain in a patient previously treated with massive doses of intravenous opioid. ( Cousins, MJ; Tanelian, DL, 1989) |
| "A patient twice developed the adult respiratory distress syndrome following an adverse reaction to administration of lidocaine." | 3.66 | Adult respiratory distress syndrome following administration of lidocaine. ( Howard, JJ; Mohsenifar, Z; Simons, SM, 1982) |
| "Lidocaine infusion of a CA755 mammary adenocarcinoma growing in the hind leg of BDF1 mice results in a significant increase in the animals' survival when combined with heating for 1 hour in a 43." | 3.66 | Hyperthermia and local anesthetics: potentiation of survival of tumor-bearing mice. ( Clifton, KH; Dennis, WH; Yatvin, MB, 1979) |
| "Lidocaine is a short-acting local anesthetic, and intravenous lidocaine has been shown to have analgesic efficacy in surgical settings." | 2.82 | Efficacy of Intravenous Lidocaine During Endoscopic Submucosal Dissection for Gastric Neoplasm: A Randomized, Double-Blind, Controlled Study. ( Choi, JB; Jeong, HW; Kim, JE; Kim, SY; Koo, BN; Lee, BH, 2016) |
| "Cancer-induced bone pain is described as dull, aching ongoing pain." | 1.42 | Behavioral and neurochemical analysis of ongoing bone cancer pain in rats. ( King, T; Navratilova, E; Okun, A; Porreca, F; Remeniuk, B; Sukhtankar, D; Xie, JY, 2015) |
| "Treatment with lidocaine caused an increase in the percentage of migrating cells (up to 75." | 1.31 | Influence of non-volatile anesthetics on the migration behavior of the human breast cancer cell line MDA-MB-468. ( Brandt, L; Garib, V; Kubens, BS; Niggemann, B; Zänker, KS, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (33.33) | 18.7374 |
| 1990's | 3 (12.50) | 18.2507 |
| 2000's | 5 (20.83) | 29.6817 |
| 2010's | 8 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gessner, DM | 1 |
| Sang, CN | 1 |
| Zhang, L | 1 |
| Hu, R | 1 |
| Cheng, Y | 1 |
| Wu, X | 1 |
| Xi, S | 1 |
| Sun, Y | 1 |
| Jiang, H | 1 |
| Remeniuk, B | 2 |
| King, T | 2 |
| Sukhtankar, D | 2 |
| Nippert, A | 1 |
| Li, N | 1 |
| Li, F | 1 |
| Cheng, K | 1 |
| Rice, KC | 1 |
| Porreca, F | 2 |
| Otunctemur, A | 1 |
| Dursun, M | 1 |
| Besiroglu, H | 1 |
| Can Polat, E | 1 |
| Cakir, SS | 1 |
| Ozbek, E | 1 |
| Karadeniz, T | 1 |
| Okun, A | 1 |
| Navratilova, E | 1 |
| Xie, JY | 1 |
| Piegeler, T | 2 |
| Schläpfer, M | 1 |
| Dull, RO | 1 |
| Schwartz, DE | 2 |
| Borgeat, A | 2 |
| Minshall, RD | 2 |
| Beck-Schimmer, B | 2 |
| Kim, JE | 1 |
| Choi, JB | 1 |
| Koo, BN | 1 |
| Jeong, HW | 1 |
| Lee, BH | 1 |
| Kim, SY | 1 |
| Votta-Velis, EG | 1 |
| Liu, G | 1 |
| Place, AT | 1 |
| Garib, V | 1 |
| Niggemann, B | 1 |
| Zänker, KS | 1 |
| Brandt, L | 1 |
| Kubens, BS | 1 |
| Sánchez Zalabardo, JM | 1 |
| Sánchez Elipe, MA | 1 |
| Regojo Zapata, O | 1 |
| Elizalde Benito, A | 1 |
| Valle Gerhold, J | 1 |
| López López, JA | 1 |
| Valdivia Uría, JG | 1 |
| Kravchick, S | 1 |
| Peled, R | 1 |
| Ben-Dor, D | 1 |
| Dorfman, D | 1 |
| Kesari, D | 1 |
| Cytron, S | 1 |
| Miyabe, M | 1 |
| Mayumi, T | 1 |
| Horikawa, D | 1 |
| Motohara, T | 1 |
| Itoh, N | 1 |
| Hayashi, H | 1 |
| Aoki, H | 1 |
| Kubota, H | 1 |
| Murakami, T | 1 |
| Dohi, S | 1 |
| Yatvin, MB | 3 |
| Abuirmeileh, NM | 1 |
| Vorpahl, JW | 2 |
| Elson, CE | 1 |
| Clark, AW | 1 |
| Robins, HI | 1 |
| Howard, JJ | 1 |
| Mohsenifar, Z | 1 |
| Simons, SM | 1 |
| Fratacci, MD | 1 |
| Kimball, WR | 1 |
| Wain, JC | 1 |
| Kacmarek, RM | 1 |
| Polaner, DM | 1 |
| Zapol, WM | 1 |
| Sugitachi, A | 1 |
| Nagano, T | 1 |
| Suzuki, A | 1 |
| Ozawa, M | 1 |
| Illek, B | 2 |
| Lizarzaburu, ME | 1 |
| Lee, V | 1 |
| Nantz, MH | 1 |
| Kurth, MJ | 1 |
| Fischer, H | 2 |
| Lahav, M | 1 |
| Levite, M | 1 |
| Bassani, L | 1 |
| Lang, A | 1 |
| Fidder, H | 1 |
| Tal, R | 1 |
| Bar-Meir, S | 1 |
| Mayer, L | 1 |
| Chowers, Y | 1 |
| Clifton, KH | 1 |
| Dennis, WH | 1 |
| Cunningham, IG | 1 |
| Lee, YK | 1 |
| Kreusel, KM | 1 |
| Hegel, U | 1 |
| Clauss, W | 1 |
| Tanelian, DL | 1 |
| Cousins, MJ | 1 |
| Ameer, B | 1 |
| Burlingame, MB | 1 |
| Harman, EM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Improving Perioperative Pain Management for Laparoscopic Surgery Due to Colon Cancer Using the Ultrasound-guided Transmuscular Quadratus Lumborum Block. A Double Blind, Randomized, Placebo Controlled Trial.[NCT03570541] | Phase 4 | 69 participants (Actual) | Interventional | 2018-06-28 | Completed | ||
| Anesthesia and Immunological and Oxidative Stress in Relation to Abdominal Cancer Surgery[NCT03974984] | 0 participants (Actual) | Observational | 2020-06-04 | Withdrawn (stopped due to Not feasable due to logistics) | |||
| Effects of Epidural Anesthesia-analgesia on Long-term Survival in Patients After Lung Cancer Surgery: A Randomized Controlled Trial[NCT02801409] | 400 participants (Actual) | Interventional | 2015-05-25 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 trials available for lidocaine and Adenocarcinoma
| Article | Year |
|---|---|
The effectivity of periprostatic nerve blockade for the pain control during transrectal ultrasound guided prostate biopsy.
Topics: Adenocarcinoma; Administration, Rectal; Aged; Anesthesia, Local; Anesthetics, Local; Biopsy, Needle; | 2013 |
Efficacy of Intravenous Lidocaine During Endoscopic Submucosal Dissection for Gastric Neoplasm: A Randomized, Double-Blind, Controlled Study.
Topics: Abdominal Pain; Adenocarcinoma; Adenoma; Administration, Intravenous; Aged; Analgesics, Opioid; Anes | 2016 |
Comparison of different local anesthesia techniques during TRUS-guided biopsies: a prospective pilot study.
Topics: Adenocarcinoma; Adjuvants, Anesthesia; Administration, Rectal; Aged; Anesthesia, Local; Anesthetics, | 2005 |
Diaphragmatic shortening after thoracic surgery in humans. Effects of mechanical ventilation and thoracic epidural anesthesia.
Topics: Adenocarcinoma; Aged; Anesthesia, Epidural; Autonomic Nerve Block; Diaphragm; Female; Humans; Lidoca | 1993 |
20 other studies available for lidocaine and Adenocarcinoma
| Article | Year |
|---|---|
Revisiting Mechanisms of Extraterritorial Allodynia.
Topics: Adenocarcinoma; Humans; Hyperalgesia; Lidocaine; Male; Middle Aged; Pain; Pain Threshold; Spinal Cor | 2017 |
Lidocaine inhibits the proliferation of lung cancer by regulating the expression of GOLT1A.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Anesthetics, Local; Antineoplastic Agents; Cell Cycle; Cell | 2017 |
Disease modifying actions of interleukin-6 blockade in a rat model of bone cancer pain.
Topics: Adenocarcinoma; Analgesics; Analysis of Variance; Anesthetics, Local; Animals; Bone Neoplasms; Bufan | 2018 |
Behavioral and neurochemical analysis of ongoing bone cancer pain in rats.
Topics: Adenocarcinoma; Analgesics, Opioid; Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Stero | 2015 |
Clinically relevant concentrations of lidocaine and ropivacaine inhibit TNFα-induced invasion of lung adenocarcinoma cells in vitro by blocking the activation of Akt and focal adhesion kinase.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Amides; Anesthetics, Local; Caveolin 1; Cell Movement; Drug | 2015 |
Clinically relevant concentrations of lidocaine and ropivacaine inhibit TNFα-induced invasion of lung adenocarcinoma cells in vitro by blocking the activation of Akt and focal adhesion kinase.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Amides; Anesthetics, Local; Caveolin 1; Cell Movement; Drug | 2015 |
Clinically relevant concentrations of lidocaine and ropivacaine inhibit TNFα-induced invasion of lung adenocarcinoma cells in vitro by blocking the activation of Akt and focal adhesion kinase.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Amides; Anesthetics, Local; Caveolin 1; Cell Movement; Drug | 2015 |
Clinically relevant concentrations of lidocaine and ropivacaine inhibit TNFα-induced invasion of lung adenocarcinoma cells in vitro by blocking the activation of Akt and focal adhesion kinase.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Amides; Anesthetics, Local; Caveolin 1; Cell Movement; Drug | 2015 |
Antimetastatic potential of amide-linked local anesthetics: inhibition of lung adenocarcinoma cell migration and inflammatory Src signaling independent of sodium channel blockade.
Topics: Adenocarcinoma; Amides; Anesthetics, Local; Cell Line, Tumor; Cell Movement; Humans; Intercellular A | 2012 |
Influence of non-volatile anesthetics on the migration behavior of the human breast cancer cell line MDA-MB-468.
Topics: Adenocarcinoma; Anesthetics; Anesthetics, Intravenous; Anesthetics, Local; Breast Neoplasms; Cell Mo | 2002 |
[Modified technique for transurethral resection of the prostate with suprapubic drainage and local anesthesia].
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Cystost | 2003 |
[Anesthetic managements for major surgery in a patient with myocardial revascularization].
Topics: Adenocarcinoma; Anesthesia, Epidural; Coronary Artery Bypass; Gastrectomy; Humans; Lidocaine; Male; | 1983 |
Biological optimization of hyperthermia: modification of tumor membrane lipids.
Topics: Adenocarcinoma; Animals; Dietary Fats; Fatty Acids; Hot Temperature; Lidocaine; Linoleic Acids; Live | 1983 |
Structural changes in murine cancer associated with hyperthermia and lidocaine.
Topics: Adenocarcinoma; Animals; Hot Temperature; Lidocaine; Mammary Neoplasms, Experimental; Mice; Mice, In | 1983 |
Adult respiratory distress syndrome following administration of lidocaine.
Topics: Adenocarcinoma; Female; Humans; Intubation, Intratracheal; Lidocaine; Lung Neoplasms; Middle Aged; R | 1982 |
[A case report of stage IV ovarian carcinoma treated with cancer chemotherapy and surgery].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; D | 1993 |
Structural determinants for activation and block of CFTR-mediated chloride currents by apigenin.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenocarcinoma; Anesthetics, Local; Apigenin; Biol | 2000 |
Lidocaine inhibits secretion of IL-8 and IL-1beta and stimulates secretion of IL-1 receptor antagonist by epithelial cells.
Topics: Adenocarcinoma; Anesthetics, Local; Bupivacaine; Colitis, Ulcerative; Colonic Neoplasms; Epithelial | 2002 |
Hyperthermia and local anesthetics: potentiation of survival of tumor-bearing mice.
Topics: Adenocarcinoma; Anesthetics, Local; Animals; Female; Hot Temperature; Lidocaine; Mammary Neoplasms, | 1979 |
The management of solitary thyroid nodules under local anaesthesia.
Topics: Adenocarcinoma; Adenoma; Adult; Anesthesia, Local; Carcinoma, Papillary; Cysts; Ethnicity; Female; H | 1975 |
Volume-sensitive basolateral K+ channels in HT-29/B6 cells: block by lidocaine, quinidine, NPPB, and Ba2+.
Topics: Adenocarcinoma; Animals; Barium; Cell Membrane Permeability; Chlorides; Colonic Neoplasms; Electroph | 1992 |
Failure of epidural opioid to control cancer pain in a patient previously treated with massive doses of intravenous opioid.
Topics: Adenocarcinoma; Bupivacaine; Cecal Neoplasms; Clonidine; Female; Humans; Hydromorphone; Infusions, I | 1989 |
Rapid mucosal absorption of topical lidocaine during bronchoscopy in the presence of oral candidiasis.
Topics: Absorption; Adenocarcinoma; Administration, Topical; Bronchoscopy; Candidiasis, Oral; Humans; Lidoca | 1989 |