lidocaine has been researched along with Acute Rheumatic Fever in 5 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Use of lidocaine hydrochloride as a diluent for benzathine penicillin G does not change the penicillin concentration in body fluids and significantly reduces the pain of injection." | 5.08 | Lidocaine as a diluent for administration of benzathine penicillin G. ( Amir, J; Cohen, YH; Ginat, S; Keller, N; Marcus, TE; Varsano, I, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Russell, K | 1 |
| Nicholson, R | 1 |
| Naidu, R | 1 |
| MOSE, K | 1 |
| ROSSEL, IB | 1 |
| STRANDBERG, B | 1 |
| Amir, J | 1 |
| Ginat, S | 1 |
| Cohen, YH | 1 |
| Marcus, TE | 1 |
| Keller, N | 1 |
| Varsano, I | 1 |
| Horiguti, S | 1 |
| Tanaka, S | 1 |
| Oppermann, J | 1 |
| Petermann, HD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| "Do NSAIDS or Executing Exercise Decrease Local Erythema, Site Swelling & Pain After INoculation: the NEED LESS PAIN Study"[NCT02807623] | 300 participants (Actual) | Interventional | 2016-09-30 | Completed | |||
| Pain Perception of Children and Youth Receiving Non-sedated Botulinum Toxin-A Injections Using the Buzzy®[NCT02273284] | 50 participants (Anticipated) | Interventional | 2014-12-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Swelling at vaccination site (NCT02807623)
Timeframe: baseline, 48-72 hours, and 21- 28 days (3 points)
| Intervention | Participants (Count of Participants) |
|---|---|
| Baseline | 0 |
| 48-72 Hours After Vaccination | 0 |
| 21-28 Days After Vaccination | 0 |
Reddening of the skin at vaccination site reported as the total number of participants with erythema over the duration of the study. (NCT02807623)
Timeframe: baseline, 48- 72 hours, 21-28 days (3 points)
| Intervention | Participants (Count of Participants) |
|---|---|
| Baseline | 0 |
| 48-72 Hours After Vaccination | 0 |
| 21-28 Days After Vaccination | 0 |
A Lactate meter was used to test the exercise group for lactate readings. Two lactate tests was performed for the exercise group at Visit 1, both pre and post Influenza vaccination. The first lactate reading was taken after the blood draw.The second lactate reading was obtained from a fingerstick from the hand opposite to the vaccination arm, ideally within 3-8 minutes after the study subject completes pushups. (NCT02807623)
Timeframe: Immediately prior to Influenza vaccine and 3-8 minutes after Influenza vaccine was administered and after push-ups were completed.
| Intervention | mmol/L (Mean) | |
|---|---|---|
| Lactate before pushups | Lactate after pushups | |
| Compound Exercise of Push-ups | 1.51 | 7.69 |
Level of Pain will be measured by validated pain scale, using a scale of 0 ( best, no pain) to 10 (worst, as bad as imaginable, completely interferes). (NCT02807623)
Timeframe: baseline, 48-72 hours and at 21-28 days ( 3 points )
| Intervention | units on a scale (Mean) | ||
|---|---|---|---|
| Visit 1 | Visit 2 | Visit 3 | |
| Compound Exercise of Push-ups | .14 | .19 | .13 |
| Ibuprofen | .39 | .56 | .28 |
| Placebo | .19 | .22 | .06 |
Baseline lab specimen (visit 1, day 0, before immunization) and repeated between 21-28 days (visit 3) after immunization to measure serologic response (NCT02807623)
Timeframe: Day 0 and between 21-28 days (2 points)
| Intervention | Titer (Mean) | |
|---|---|---|
| Baseline (day 0, visit 1) | Followup (between 21-28 days, visit 3) | |
| Compound Exercise of Push-ups | 214.80 | 345.09 |
| Ibuprofen | 171.00 | 239.25 |
| Placebo | 216.75 | 343.03 |
Baseline lab specimen (visit 1, day 0, before immunization) and repeated between 21-28 days (visit 3) after immunization to measure serologic response (NCT02807623)
Timeframe: Day 0 and between 21-28 days (2 points)
| Intervention | Titer (Mean) | |
|---|---|---|
| Baseline (day 0, visit 1) | Followup (between 21-28 days, visit 3) | |
| Compound Exercise of Push-ups | 149.22 | 232.58 |
| Ibuprofen | 177.78 | 243.13 |
| Placebo | 221.09 | 296.66 |
Baseline lab specimen (visit 1, day 0, before immunization) and repeated between 21-28 days (visit 3) after immunization to measure serologic response (NCT02807623)
Timeframe: Day 0 and between 21-28 days (2 points)
| Intervention | Titer (Mean) | |
|---|---|---|
| Baseline (day 0, visit 1) | Followup (between 21-28 days, visit 3) | |
| Compound Exercise of Push-ups | 26.00 | 41.02 |
| Ibuprofen | 17.41 | 25.47 |
| Placebo | 26.09 | 34.09 |
Baseline lab specimen (visit 1, day 0, before immunization) and repeated between 21-28 days (visit 3) after immunization to measure serologic response (NCT02807623)
Timeframe: Day 0 and between 21-28 days (2 points)
| Intervention | Titer (Mean) | |
|---|---|---|
| Baseline (day 0, visit 1) | Followup (between 21-28 days, visit 3) | |
| Compound Exercise of Push-ups | 32.89 | 49.07 |
| Ibuprofen | 40.16 | 47.34 |
| Placebo | 36.69 | 44.78 |
1 trial available for lidocaine and Acute Rheumatic Fever
| Article | Year |
|---|---|
Lidocaine as a diluent for administration of benzathine penicillin G.
Topics: Adolescent; Anesthetics, Local; Antibiotic Prophylaxis; Child; Cross-Over Studies; Double-Blind Meth | 1998 |
4 other studies available for lidocaine and Acute Rheumatic Fever
| Article | Year |
|---|---|
Reducing the pain of intramuscular benzathine penicillin injections in the rheumatic fever population of Counties Manukau District Health Board.
Topics: Adolescent; Adult; Analysis of Variance; Anesthetics, Local; Child; Child, Preschool; Fear; Female; | 2014 |
Reducing the pain of intramuscular benzathine penicillin injections in the rheumatic fever population of Counties Manukau District Health Board.
Topics: Adolescent; Adult; Analysis of Variance; Anesthetics, Local; Child; Child, Preschool; Fear; Female; | 2014 |
Reducing the pain of intramuscular benzathine penicillin injections in the rheumatic fever population of Counties Manukau District Health Board.
Topics: Adolescent; Adult; Analysis of Variance; Anesthetics, Local; Child; Child, Preschool; Fear; Female; | 2014 |
Reducing the pain of intramuscular benzathine penicillin injections in the rheumatic fever population of Counties Manukau District Health Board.
Topics: Adolescent; Adult; Analysis of Variance; Anesthetics, Local; Child; Child, Preschool; Fear; Female; | 2014 |
[ARTHRITIS CAUSED BY SALMONELLA TYPHIMURIUM].
Topics: Arthritis; Child; Diagnosis, Differential; Humans; Injections; Injections, Intra-Articular; Lidocain | 1964 |
Epipharyngitis and rheumatism.
Topics: Adolescent; Adult; Arthritis, Rheumatoid; Blood Sedimentation; Body Temperature; Child; Chlorides; E | 1965 |
[Clarification of non-allergic reactions after benzathine penicillin injections in children with rheumatic fever by means of electroencephalographic studies].
Topics: Adolescent; Central Nervous System; Child; Electroencephalography; Electrophysiology; Female; Humans | 1970 |